Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0147 | 0.2971 | 0.2971 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0396 | 0.9028 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0396 | 0.9028 | 0.9028 |
Echinococcus granulosus | acetylcholinesterase | 0.0147 | 0.2971 | 0.2971 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0396 | 0.9028 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.027 | 0.5976 | 0.6619 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.027 | 0.5976 | 0.6619 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0396 | 0.9028 | 0.9028 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0147 | 0.2971 | 0.3292 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.1271 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0147 | 0.2971 | 0.2971 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0045 | 0.0481 | 0.0481 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0147 | 0.2971 | 0.2971 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0045 | 0.0481 | 0.0481 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0147 | 0.2971 | 0.3292 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1271 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0396 | 0.9028 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0147 | 0.2971 | 0.3292 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.1271 | 0.1408 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.2971 | 0.3292 |
Brugia malayi | Carboxylesterase family protein | 0.0147 | 0.2971 | 0.3292 |
Brugia malayi | Carboxylesterase family protein | 0.0147 | 0.2971 | 0.3292 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1271 | 0.1271 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1271 | 0.1408 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1271 | 0.5 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.2971 | 0.3292 |
Echinococcus multilocularis | expressed protein | 0.0436 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0147 | 0.2971 | 0.2971 |
Echinococcus granulosus | acetylcholinesterase | 0.0147 | 0.2971 | 0.2971 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.1271 | 0.5 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.1271 | 0.5 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.1271 | 0.1271 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.1271 | 0.1408 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.