Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.008 | 0.083 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0152 | 0.2616 | 0.2616 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.2616 | 0.3614 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0152 | 0.2616 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0152 | 0.2616 | 0.2616 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.008 | 0.083 | 0.5 |
Echinococcus multilocularis | expressed protein | 0.0451 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0152 | 0.2616 | 0.2616 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 0.5772 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.008 | 0.083 | 0.5 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.008 | 0.083 | 0.083 |
Loa Loa (eye worm) | carboxylesterase | 0.0152 | 0.2616 | 0.3614 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.008 | 0.083 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0152 | 0.2616 | 0.3614 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.008 | 0.083 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0152 | 0.2616 | 0.2616 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.008 | 0.083 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2616 | 0.3614 |
Echinococcus granulosus | acetylcholinesterase | 0.0152 | 0.2616 | 0.2616 |
Brugia malayi | follicle stimulating hormone receptor | 0.028 | 0.5772 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0152 | 0.2616 | 0.3614 |
Echinococcus multilocularis | acetylcholinesterase | 0.0152 | 0.2616 | 0.2616 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2616 | 0.3614 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.