Detailed information for compound 2070182

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 316.358 | Formula: C15H20N6O2
  • H donors: 1 H acceptors: 5 LogP: 0.55 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1nc(C)ncc1C(=O)N1CCOC(C1)c1[nH]nc(n1)C
  • InChi: 1S/C15H20N6O2/c1-4-12-11(7-16-9(2)17-12)15(22)21-5-6-23-13(8-21)14-18-10(3)19-20-14/h7,13H,4-6,8H2,1-3H3,(H,18,19,20)
  • InChiKey: CINMOTCHTWFJED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0164 0.6787 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.1424 0.2674
Schistosoma mansoni coup transcription factor 0.0042 0.1424 0.2674
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0435 0.0745
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0435 0.0435
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0435 0.0435
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0435 0.0641
Brugia malayi hypothetical protein 0.0022 0.0541 0.0702
Echinococcus granulosus cathepsin L cysteine proteinase 0.0012 0.0069 0.0069
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0043 0.1429 0.9347
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.1424 0.2098
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.1424 0.2017
Brugia malayi nuclear hormone receptor 0.0042 0.1424 0.2017
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.1424 0.2674
Echinococcus granulosus nuclear factor of activated T cells 5 0.0052 0.1829 0.1829
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.1424 0.2017
Brugia malayi conserved hypotetical protein 0.002 0.0435 0.0544
Echinococcus multilocularis cysteine protease 0.0012 0.0069 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Brugia malayi hypothetical protein 0.0046 0.1591 0.2265
Brugia malayi nuclear receptor NHR-88 0.0042 0.1424 0.2017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.1424 0.2098
Schistosoma mansoni hypothetical protein 0.0025 0.0664 0.1244
Loa Loa (eye worm) hypothetical protein 0.0022 0.0541 0.0797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.1424 0.276
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.1424 0.2017
Echinococcus granulosus neuroglian 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Brugia malayi hypoxia-induced factor 1 0.0105 0.4207 0.616
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.1524 1
Schistosoma mansoni nuclear hormone receptor 0.002 0.0435 0.0813
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.1424 0.1424
Echinococcus multilocularis netrin receptor unc 5 0.0013 0.0113 0.0113
Echinococcus multilocularis thyroid hormone receptor alpha 0.0131 0.5317 0.5317
Schistosoma mansoni nuclear receptor 0.002 0.0435 0.0813
Entamoeba histolytica hypothetical protein 0.0025 0.0664 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0059 0.2148 0.2148
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0541 0.1012
Echinococcus granulosus netrin receptor unc 5 0.0013 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0057 0.2077 0.3061
Brugia malayi hypothetical protein 0.0114 0.4598 0.6742
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0541 0.0702
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0069 0.0069
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.1424 0.2017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0435 0.0813
Echinococcus multilocularis tumor protein p63 0.0237 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0069 0.0125
Brugia malayi Fibroblast growth factor family protein 0.0077 0.2941 0.4275
Trypanosoma cruzi major cysteine proteinase, putative 0.0035 0.1102 0.7098
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.1424 0.2017
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0435 0.0435
Echinococcus granulosus cathepsin l1 0.0012 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0025 0.0664 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0012 0.0069 0.0069
Brugia malayi Nuclear hormone receptor E75 0.002 0.0435 0.0544
Loa Loa (eye worm) hypothetical protein 0.0011 0.0029 0.0042
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0041 0.1353 0.8824
Schistosoma mansoni jun-related protein 0.0048 0.1662 0.3122
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.1424 0.276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.1424 0.2017
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0435 0.0435
Giardia lamblia Hypothetical protein 0.0077 0.2941 0.5
Onchocerca volvulus 0.0035 0.1081 0.2061
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.1424 0.2674
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.1424 0.1424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Onchocerca volvulus 0.0042 0.1424 0.276
Loa Loa (eye worm) DR-78 0.002 0.0435 0.0641
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.1424 0.2017
Onchocerca volvulus 0.0046 0.1591 0.3099
Onchocerca volvulus 0.002 0.0435 0.0745
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0435 0.0813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus granulosus jun protein 0.0059 0.2148 0.2148
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0043 0.1429 0.5
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.1424 0.1424
Onchocerca volvulus Tyrosine kinase homolog 0.0123 0.4978 1
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0435 0.0641
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0012 0.0069 0.0102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.1424 0.2098
Loa Loa (eye worm) hypothetical protein 0.0022 0.0541 0.0797
Brugia malayi nuclear receptor NHR-67 0.002 0.0435 0.0544
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0435 0.0544
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.1424 0.1424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Loa Loa (eye worm) hypothetical protein 0.0022 0.0541 0.0797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus multilocularis jun protein 0.0059 0.2148 0.2148
Brugia malayi Nuclear hormone receptor E75 0.002 0.0435 0.0544
Brugia malayi nuclear receptor RXR 0.0022 0.0541 0.0702
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.1424 0.1424
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Plasmodium vivax vivapain-2 0.0012 0.0069 0.5
Echinococcus multilocularis transfer RNA-Lys 0.0025 0.0665 0.0665
Schistosoma mansoni single-minded 0.0034 0.1056 0.1981
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.1424 0.2017
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0088 0.3444 0.3444
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0435 0.0435
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0541 0.0541
Echinococcus multilocularis neuroglian 0.001 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.0045 0.1524 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0025 0.0664 0.0664
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.1429 1
Loa Loa (eye worm) fibroinase 0.0012 0.0069 0.0102
Loa Loa (eye worm) hypothetical protein 0.0077 0.2941 0.4334
Schistosoma mansoni thyroid hormone receptor 0.0131 0.5317 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.1424 0.2098
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.1424 0.2017
Brugia malayi bHLH-PAS transcription factor 0.0025 0.0665 0.0887
Schistosoma mansoni zinc finger protein 0.002 0.0435 0.0813
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Brugia malayi hypothetical protein 0.0025 0.0664 0.0885
Leishmania major cathepsin L-like protease 0.0045 0.1524 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Trypanosoma cruzi cruzipain precursor, putative 0.0045 0.1524 1
Brugia malayi nuclear hormone receptor 0.002 0.0435 0.0544
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0541 0.0541
Schistosoma mansoni cell adhesion molecule 0.0011 0.0029 0.0048
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0435 0.0435
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.1424 0.1424
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.1424 0.2098
Onchocerca volvulus 0.0025 0.0665 0.1213
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.1424 0.2017
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0052 0.1829 0.1829
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Echinococcus granulosus twitchin 0.001 0.0003 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0069 0.0069
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.1424 0.1424
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0435 0.0544
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.5363 0.788
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.1424 0.1424
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.1424 0.1424
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.1429 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.1424 0.1424
Brugia malayi hypothetical protein 0.0022 0.0541 0.0702
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0012 0.0069 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Schistosoma mansoni hypothetical protein 0.0088 0.3444 0.6476
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Onchocerca volvulus 0.002 0.0435 0.0745
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0043 0.1429 0.2684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Schistosoma mansoni transcription factor LCR-F1 0.0025 0.0664 0.1244
Schistosoma mansoni nuclear hormone receptor 0.0042 0.1424 0.2674
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0435 0.0435
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0132 0.5363 0.7902
Brugia malayi Fibroblast growth factor family protein 0.0077 0.2941 0.4275
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0435 0.0544
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0541 0.1012
Loa Loa (eye worm) hypothetical protein 0.0114 0.4598 0.6775
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.1524 1
Brugia malayi tailless protein 0.002 0.0435 0.0544
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0435 0.0641
Brugia malayi hypothetical protein 0.002 0.0435 0.0544
Schistosoma mansoni hypothetical protein 0.0048 0.1662 0.3122
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0069 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Loa Loa (eye worm) hypothetical protein 0.0012 0.0069 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0025 0.0664 0.0664
Brugia malayi nuclear receptor NHR-88 0.002 0.0435 0.0544
Mycobacterium ulcerans aldehyde dehydrogenase 0.0043 0.1429 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.1424 0.1424
Loa Loa (eye worm) cysteine protease 0.0012 0.0069 0.0102
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0059 0.2148 0.2148
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0435 0.0813
Plasmodium falciparum cysteine proteinase falcipain 3 0.0012 0.0069 0.5
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.1424 0.2017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.1424 0.1424
Leishmania major cathepsin L-like protease 0.0045 0.1524 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.012 0.0177
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.1424 0.2674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0113 0.0066
Brugia malayi steroid hormone receptor 0.0042 0.1424 0.2017
Loa Loa (eye worm) ctsf protein 0.0012 0.0069 0.0102
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0541 0.0797
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Echinococcus granulosus roundabout 2 0.0013 0.012 0.012
Brugia malayi PAS domain containing protein 0.0034 0.1056 0.1469
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.1081 0.2028
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0069 0.0069
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0043 0.1429 0.1429
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0435 0.0544
Echinococcus multilocularis cysteine protease 0.0012 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.1424 0.2017
Echinococcus granulosus single minded 2 0.0025 0.0665 0.0665
Brugia malayi hypothetical protein 0.002 0.0435 0.0544
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.1424 0.2098
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.1424 0.1424
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.1424 0.1424
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0012 0.0069 0.5
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.1424 0.2674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.1424 0.276
Loa Loa (eye worm) hypothetical protein 0.0077 0.2941 0.4334
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.1424 0.2674
Loa Loa (eye worm) hypoxia-induced factor 1 0.0105 0.4207 0.6199
Schistosoma mansoni nuclear hormone receptor 0.002 0.0435 0.0813
Loa Loa (eye worm) hypothetical protein 0.0035 0.1081 0.1593
Loa Loa (eye worm) hypothetical protein 0.0022 0.0541 0.0797
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0012 0.0069 0.5
Loa Loa (eye worm) hypothetical protein 0.0013 0.012 0.0177
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Brugia malayi bZIP transcription factor family protein 0.0059 0.2148 0.3095
Onchocerca volvulus Netrin receptor homolog 0.0012 0.0088 0.0038
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0088 0.3444 0.3444
Plasmodium vivax vivapain-2 0.0012 0.0069 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.1424 0.2098
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Schistosoma mansoni nuclear receptor 0.002 0.0435 0.0813
Entamoeba histolytica hypothetical protein 0.0025 0.0664 1
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.1524 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.1424 0.2674
Brugia malayi nuclear receptor RXR 0.002 0.0435 0.0544
Brugia malayi follicle stimulating hormone receptor 0.0164 0.6787 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0043 0.1429 0.1429
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0435 0.0435
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.1424 0.1424
Toxoplasma gondii aldehyde dehydrogenase 0.0043 0.1429 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0435 0.0745
Schistosoma mansoni aldehyde dehydrogenase 0.0043 0.1429 0.2684
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.1424 0.2098
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.1424 0.2674
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0012 0.0069 0.5
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.1424 0.2017
Echinococcus granulosus FTZ F1 alpha 0.0042 0.1424 0.1424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0435 0.0435
Brugia malayi ecdysteroid receptor 0.0042 0.1424 0.2017
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.1424 0.2017
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.1424 0.2017
Brugia malayi ecdysone receptor 0.002 0.0435 0.0544
Schistosoma mansoni aryl hydrocarbon receptor 0.0034 0.1056 0.1981
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Entamoeba histolytica hypothetical protein 0.0025 0.0664 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0011 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0435 0.0641
Loa Loa (eye worm) hypothetical protein 0.0022 0.0541 0.0797
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0541 0.0702
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.1424 0.1424
Schistosoma mansoni thyroid hormone receptor 0.0131 0.5317 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0435 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0069 0.5
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0069 0.0125
Onchocerca volvulus 0.0121 0.4886 0.9813
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.1424 0.2674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.1524 0.5
Schistosoma mansoni netrin receptor unc5 0.0013 0.0113 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.1424 0.2017
Loa Loa (eye worm) hypothetical protein 0.0042 0.1424 0.2098
Echinococcus multilocularis roundabout 2 0.0013 0.012 0.012
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0069 0.0069

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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