Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0163 | 0.0673 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | conserved hypotetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0077 | 0.0021 | 0.0021 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0163 | 0.0673 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0086 | 0.0091 | 0.0091 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0077 | 0.0021 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Schistosoma mansoni | zinc finger protein | 0.0077 | 0.0021 | 0.0024 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0219 | 0.0219 |
Brugia malayi | tailless protein | 0.0077 | 0.0021 | 0.0021 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0163 | 0.0673 | 0.0653 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0077 | 0.0021 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0219 | 0.0219 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0163 | 0.0673 | 0.0833 |
Echinococcus granulosus | FTZ F1 alpha | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0077 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0163 | 0.0673 | 0.0771 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0077 | 0.0021 | 0.0024 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0163 | 0.0673 | 0.0673 |
Schistosoma mansoni | coup transcription factor | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0086 | 0.0091 | 0.0091 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0163 | 0.0673 | 0.0833 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0163 | 0.0673 | 0.0673 |
Schistosoma mansoni | nuclear hormone receptor | 0.0077 | 0.0021 | 0.0024 |
Echinococcus granulosus | geminin | 0.0396 | 0.2441 | 0.2798 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0163 | 0.0673 | 0.0673 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.2441 | 0.2798 |
Brugia malayi | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Schistosoma mansoni | eyes absent homolog | 0.0103 | 0.0219 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0163 | 0.0673 | 0.0673 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0077 | 0.0021 | 0.0024 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0077 | 0.0021 | 0.0024 |
Brugia malayi | hypothetical protein | 0.0103 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0163 | 0.0673 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | nuclear receptor RXR | 0.0077 | 0.0021 | 0.0021 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.0673 | 0.0771 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0163 | 0.0673 | 0.0833 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0163 | 0.0673 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.1392 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0086 | 0.0091 | 0.0091 |
Brugia malayi | ecdysone receptor | 0.0077 | 0.0021 | 0.0021 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0086 | 0.0091 | 0.0104 |
Brugia malayi | nuclear receptor NHR-67 | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0163 | 0.0673 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0163 | 0.0673 | 0.0673 |
Schistosoma mansoni | nuclear hormone receptor | 0.0077 | 0.0021 | 0.0024 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0077 | 0.0021 | 0.0026 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | nuclear receptor | 0.0077 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0077 | 0.0021 | 0.0021 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1392 | 1 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0874 | 0.607 | 0.7519 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0077 | 0.0021 | 0.0026 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0163 | 0.0673 | 0.0833 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0077 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0163 | 0.0673 | 0.0833 |
Brugia malayi | nuclear receptor NHR-88 | 0.0077 | 0.0021 | 0.0021 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0086 | 0.0091 | 0.0112 |
Schistosoma mansoni | nuclear hormone receptor | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0086 | 0.0091 | 0.0091 |
Schistosoma mansoni | nuclear receptor | 0.0077 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Echinococcus multilocularis | geminin | 0.0396 | 0.2441 | 0.3024 |
Brugia malayi | steroid hormone receptor | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0077 | 0.0021 | 0.0024 |
Schistosoma mansoni | thyroid hormone receptor | 0.0163 | 0.0673 | 0.0771 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.1224 | 0.8724 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0163 | 0.0673 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | nuclear hormone receptor | 0.0077 | 0.0021 | 0.0021 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0077 | 0.0021 | 0.0021 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0163 | 0.0673 | 0.0833 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0163 | 0.0673 | 0.0771 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.0673 | 0.0833 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0163 | 0.0673 | 0.0771 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0086 | 0.0091 | 0.0104 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | nuclear hormone receptor | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0077 | 0.0021 | 0.0024 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0077 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0091 | 0.0091 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0077 | 0.0021 | 0.0021 |
Onchocerca volvulus | 0.0163 | 0.0673 | 0.0653 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0077 | 0.0021 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.2441 | 0.2798 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | nuclear receptor NHR-88 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | DR-78 | 0.0077 | 0.0021 | 0.0021 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0163 | 0.0673 | 0.0771 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0163 | 0.0673 | 0.0771 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1224 | 0.8724 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0673 | 0.0673 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1138 | 0.8072 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0163 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0163 | 0.0673 | 0.0673 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0163 | 0.0673 | 0.0673 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0077 | 0.0021 | 0.0024 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0086 | 0.0091 | 0.0104 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0077 | 0.0021 | 0.0021 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.