Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0059 | 0.057 | 0.057 |
Brugia malayi | nuclear hormone receptor | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0059 | 0.057 | 0.057 |
Schistosoma mansoni | thyroid hormone receptor | 0.0059 | 0.057 | 0.057 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0059 | 0.057 | 0.057 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.0921 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0419 | 0.7904 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.0921 | 0.0921 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0059 | 0.057 | 0.0609 |
Schistosoma mansoni | nuclear hormone receptor | 0.0059 | 0.057 | 0.057 |
Brugia malayi | ecdysteroid receptor | 0.0419 | 0.7904 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 0.3532 | 0.3773 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0059 | 0.057 | 0.057 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0059 | 0.057 | 0.057 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0059 | 0.057 | 0.0609 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0059 | 0.057 | 0.0721 |
Echinococcus granulosus | FTZ F1 alpha | 0.0059 | 0.057 | 0.057 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0921 | 0.0921 |
Brugia malayi | RNA binding protein | 0.0076 | 0.0921 | 0.1165 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0059 | 0.057 | 0.057 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.0921 | 0.1165 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0059 | 0.057 | 0.0609 |
Echinococcus granulosus | geminin | 0.0205 | 0.3532 | 0.3532 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0059 | 0.057 | 0.0609 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0059 | 0.057 | 0.057 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0491 | 0.9362 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0921 | 0.0921 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.3532 | 0.3532 |
Schistosoma mansoni | coup transcription factor | 0.0059 | 0.057 | 0.057 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.0921 | 0.1165 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.0921 | 0.1165 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | steroid hormone receptor | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0059 | 0.057 | 0.057 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0059 | 0.057 | 0.057 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.0921 | 0.1165 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.0921 | 0.0983 |
Schistosoma mansoni | thyroid hormone receptor | 0.0059 | 0.057 | 0.057 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0059 | 0.057 | 0.0609 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0059 | 0.057 | 0.0609 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0522 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0059 | 0.057 | 0.0721 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0059 | 0.057 | 0.0609 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0059 | 0.057 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0059 | 0.057 | 0.057 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0419 | 0.7904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0921 | 0.0921 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0059 | 0.057 | 0.0609 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0059 | 0.057 | 0.0721 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0059 | 0.057 | 0.057 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0059 | 0.057 | 0.057 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0059 | 0.057 | 0.057 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0059 | 0.057 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0059 | 0.057 | 0.0721 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0059 | 0.057 | 0.057 |
Brugia malayi | nuclear receptor NHR-88 | 0.0059 | 0.057 | 0.0721 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0059 | 0.057 | 0.057 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.3532 | 0.3532 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.057 | 0.0721 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.