Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0055 | 0.0759 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0055 | 0.0759 | 0.0759 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0055 | 0.0759 | 1 |
Brugia malayi | steroid hormone receptor | 0.0055 | 0.0759 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0081 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0055 | 0.0759 | 0.196 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0029 | 0.0081 | 0.0081 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0055 | 0.0759 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0759 | 0.858 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0055 | 0.0759 | 0.858 |
Brugia malayi | nuclear hormone receptor | 0.0055 | 0.0759 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0759 | 0.0759 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0759 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0055 | 0.0759 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0759 | 0.0759 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0055 | 0.0759 | 0.0759 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0055 | 0.0759 | 0.196 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0759 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0055 | 0.0759 | 0.196 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0759 | 0.858 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0055 | 0.0759 | 0.196 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0081 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0759 | 0.858 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0029 | 0.0081 | 0.021 |
Onchocerca volvulus | 0.0055 | 0.0759 | 0.858 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0174 | 0.3875 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0081 | 0.0919 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0055 | 0.0759 | 0.858 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0055 | 0.0759 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0055 | 0.0759 | 0.196 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0081 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0759 | 0.858 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0759 | 0.858 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0055 | 0.0759 | 0.858 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.0759 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0174 | 0.3875 | 0.3875 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0759 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0055 | 0.0759 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.0759 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0055 | 0.0759 | 0.196 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0089 | 0.1649 | 0.1649 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0081 | 0.0919 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0055 | 0.0759 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0029 | 0.0081 | 0.0919 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0081 | 0.0919 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0029 | 0.0081 | 0.0081 |
Schistosoma mansoni | thyroid hormone receptor | 0.0055 | 0.0759 | 0.196 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0055 | 0.0759 | 0.0759 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0759 | 0.858 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0055 | 0.0759 | 0.196 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0029 | 0.0081 | 0.021 |
Echinococcus multilocularis | tumor protein p63 | 0.0408 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0055 | 0.0759 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0055 | 0.0759 | 0.858 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.0759 | 0.0759 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0055 | 0.0759 | 0.196 |
Echinococcus granulosus | FTZ F1 alpha | 0.0055 | 0.0759 | 0.0759 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.0759 | 0.0759 |
Schistosoma mansoni | thyroid hormone receptor | 0.0055 | 0.0759 | 0.196 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0759 | 0.858 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0055 | 0.0759 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.0759 | 0.0759 |
Schistosoma mansoni | nuclear hormone receptor | 0.0055 | 0.0759 | 0.196 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0081 | 0.0919 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0055 | 0.0759 | 0.858 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0055 | 0.0759 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.0759 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0055 | 0.0759 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0081 | 0.0919 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0055 | 0.0759 | 0.0759 |
Brugia malayi | nuclear receptor RXR | 0.0029 | 0.0081 | 0.1071 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0081 | 0.1071 |
Onchocerca volvulus | 0.006 | 0.0885 | 1 | |
Schistosoma mansoni | cellular tumor antigen P53 | 0.006 | 0.0885 | 0.2284 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0089 | 0.1649 | 0.1649 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0145 | 0.3115 | 0.3115 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0885 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0055 | 0.0759 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0055 | 0.0759 | 0.196 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0055 | 0.0759 | 0.0759 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0055 | 0.0759 | 0.0759 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.