Detailed information for compound 2071310

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 321.418 | Formula: C16H27N5O2
  • H donors: 1 H acceptors: 3 LogP: 1.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(CN1CCCC1Cn1nc(nc1C)C)NC1CCOCC1
  • InChi: 1S/C16H27N5O2/c1-12-17-13(2)21(19-12)10-15-4-3-7-20(15)11-16(22)18-14-5-8-23-9-6-14/h14-15H,3-11H2,1-2H3,(H,18,22)
  • InChiKey: CZRKFOKSUHELBC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans hypothetical protein 0.0038 0.014 0.1653
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0364 1
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0175 0.0178
Brugia malayi nuclear hormone receptor 0.0249 0.1781 0.1761
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.014 0.1162
Echinococcus granulosus cathepsin L 0.0078 0.045 0.0502
Giardia lamblia Cysteine protease 0.0028 0.0061 0.1548
Onchocerca volvulus 0.0249 0.1781 0.4422
Echinococcus multilocularis serotonin receptor 0.0043 0.0175 0.0178
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1114 0.8508 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.0246
Schistosoma mansoni opsin-like receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0524 0.3914 0.3899
Onchocerca volvulus 0.0122 0.0795 0.1887
Schistosoma mansoni coup transcription factor 0.0528 0.395 0.4627
Brugia malayi Dopamine receptor 0.0043 0.0175 0.0151
Onchocerca volvulus 0.0043 0.0175 0.0292
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Echinococcus granulosus GA binding protein alpha chain 0.0084 0.0498 0.0558
Trichomonas vaginalis esterase, putative 0.0038 0.014 0.1162
Echinococcus granulosus lamin 0.0058 0.0298 0.0323
Schistosoma mansoni opsin-like receptor 0.0043 0.0175 0.0178
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0096 0.0041
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0151 0.1021 0.1175
Schistosoma mansoni cathepsin F (C01 family) 0.0151 0.1021 0.1175
Onchocerca volvulus 0.0388 0.2859 0.7195
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0167 0.0168
Echinococcus granulosus neuropeptide receptor 0.0043 0.0175 0.0178
Giardia lamblia Cathepsin L-like protease 0.0028 0.0061 0.1548
Schistosoma mansoni gabp alpha 0.0084 0.0498 0.0558
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0528 0.395 0.4627
Schistosoma mansoni hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni cathepsin s 0.005 0.0233 0.0246
Brugia malayi nuclear receptor NHR-67 0.0249 0.1781 0.1761
Brugia malayi Cytochrome P450 family protein 0.0032 0.0096 0.0072
Echinococcus granulosus lamin dm0 0.0058 0.0298 0.0323
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0249 0.1781 0.2071
Brugia malayi CXXC zinc finger family protein 0.0035 0.0114 0.009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0136 0.0132
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1057 0.8063 0.9476
Schistosoma mansoni biogenic amine receptor 0.0043 0.0175 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0249 0.1781 0.2071
Brugia malayi GnHR receptor homolog 0.0043 0.0175 0.0151
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0176 0.0298
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0528 0.395 0.3935
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0167 0.0125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Echinococcus multilocularis GA binding protein alpha chain 0.0084 0.0498 0.0558
Leishmania major cathepsin L-like protease 0.0151 0.1021 0.1156
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.014 0.0579
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.0632 0.0716
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.023 0.027
Schistosoma mansoni nuclear receptor 0.0249 0.1781 0.2071
Entamoeba histolytica cysteine proteinase, putative 0.0078 0.045 0.4276
Echinococcus granulosus Nuclear hormone receptor HR96 0.0249 0.1781 0.2071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0528 0.395 0.4627
Echinococcus granulosus cathepsin l1 0.0101 0.0632 0.0716
Brugia malayi follicle stimulating hormone receptor 0.0043 0.0175 0.0151
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0167 0.0143
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0364 0.0785
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0115 0.0091
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Brugia malayi ecdysone receptor 0.0249 0.1781 0.1761
Brugia malayi Melatonin receptor type 1A 0.0043 0.0175 0.0151
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0175 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0528 0.395 0.4627
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0175 0.0178
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Onchocerca volvulus 0.0151 0.1021 0.2467
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0249 0.1781 0.4422
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0043 0.0175 0.0151
Echinococcus multilocularis cathepsin b 0.0028 0.0061 0.0044
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.055 0.4116 0.4823
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0528 0.395 0.3935
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0175 0.0178
Schistosoma mansoni cathepsin B (C01 family) 0.0028 0.0061 0.0044
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0175 0.0178
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0364 0.0401
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0175 0.0178
Brugia malayi hypothetical protein 0.0249 0.1781 0.1761
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0647 0.4876 0.5718
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0151 0.1021 0.1175
Echinococcus granulosus somatostatin receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0167 0.0168
Schistosoma mansoni hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni carbonic anhydrase-related 0.0524 0.3914 0.4585
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0528 0.395 0.3935
Brugia malayi Serotonin receptor 0.0043 0.0175 0.0151
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0176 0.0179
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Trypanosoma brucei carbonic anhydrase-like protein 0.1114 0.8508 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0528 0.395 0.3935
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Schistosoma mansoni neuropeptide F-like receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0167 0.0168
Toxoplasma gondii protease inhibitor PI2 0.0043 0.0176 0.0298
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0078 0.045 0.0502
Loa Loa (eye worm) cathepsin B 0.0028 0.0061 0.0044
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0528 0.395 0.3935
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0151 0.1021 0.1175
Echinococcus granulosus sex peptide receptor 0.0043 0.0175 0.0178
Schistosoma mansoni agrin 0.0043 0.0176 0.0179
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni hypothetical protein 0.0305 0.2216 0.2583
Brugia malayi nuclear hormone receptor 0.0528 0.395 0.3935
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus granulosus g protein coupled receptor 0.0043 0.0175 0.0178
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.014 0.0093
Brugia malayi Dopamine receptor protein 2 0.0043 0.0175 0.0151
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0061 0.0373
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.014 0.0579
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0175 0.0178
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1114 0.8508 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0042 0.005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0279 0.2013 0.2345
Brugia malayi polk-prov protein 0.0038 0.0136 0.0112
Schistosoma mansoni alpha-1 adrenergic receptor 0.0043 0.0175 0.0178
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0043 0.0175 0.0151
Schistosoma mansoni follistatin 0.0043 0.0176 0.0179
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0355 0.0762
Schistosoma mansoni retinoic acid receptor RXR 0.0647 0.4876 0.5718
Onchocerca volvulus Neuropeptide F receptor homolog 0.0043 0.0175 0.0292
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0028 0.0061 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0028 0.0061 0.0373
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0368 0.2707 0.3162
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0249 0.1781 0.2071
Echinococcus granulosus serotonin receptor 0.0043 0.0175 0.0178
Toxoplasma gondii hypothetical protein 0.0524 0.3914 1
Echinococcus multilocularis neuropeptides capa receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0028 0.0061 0.1548
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Schistosoma mansoni zinc finger protein 0.0249 0.1781 0.2071
Giardia lamblia Cysteine protease 0.0028 0.0061 0.1548
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Brugia malayi nuclear receptor NHR-88 0.0249 0.1781 0.1761
Brugia malayi SPARC precursor 0.0043 0.0176 0.0152
Trypanosoma brucei RNA helicase, putative 0.0055 0.0271 0.0318
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1114 0.8508 1
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0175 0.0178
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0528 0.395 0.4627
Brugia malayi G protein-coupled receptor F59B2.13 0.0043 0.0175 0.0151
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0364 0.038
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0364 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0528 0.395 0.4627
Leishmania major cathepsin L-like protease 0.0577 0.4327 0.5061
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0176 0.0152
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0096 0.0084
Entamoeba histolytica cysteine proteinase 1, putative 0.0078 0.045 0.4276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0167 0.143
Brugia malayi ORL1-like opioid receptor 0.0043 0.0175 0.0151
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Brugia malayi larval opioid receptor 0.0043 0.0175 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0528 0.395 0.3935
Onchocerca volvulus 0.0043 0.0175 0.0292
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0043 0.0176 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.045 0.4276
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.0078 0.045 0.4276
Brugia malayi prostaglandin transporter 0.0063 0.0331 0.0307
Echinococcus multilocularis neuropeptide receptor 0.0043 0.0175 0.0178
Brugia malayi neuropeptide F receptor 0.0043 0.0175 0.0151
Loa Loa (eye worm) hypothetical protein 0.0279 0.2013 0.2345
Echinococcus multilocularis g-protein coupled receptor 0.0043 0.0175 0.0178
Onchocerca volvulus Cathepsin F homolog 0.0151 0.1021 0.2467
Onchocerca volvulus 0.0101 0.0632 0.1467
Loa Loa (eye worm) hypothetical protein 0.0043 0.0176 0.0179
Schistosoma mansoni growth hormone secretagogue receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0279 0.2013 0.2345
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0528 0.395 0.4627
Plasmodium vivax unspecified product 0.005 0.0233 0.0636
Schistosoma mansoni thyroid hormone receptor 0.1078 0.8222 0.9663
Onchocerca volvulus Putative organic anion transporter 0.0063 0.0331 0.0692
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0249 0.1781 0.2071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus multilocularis carbonic anhydrase 0.0524 0.3914 0.4585
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0176 0.0298
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0043 0.0175 0.0178
Echinococcus granulosus g-protein coupled receptor 0.0043 0.0175 0.0178
Trypanosoma cruzi cysteine proteinase, putative 0.0078 0.045 0.046
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0043 0.0175 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0632 0.6097
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0096 0.0084
Loa Loa (eye worm) hypothetical protein 0.0058 0.0298 0.0323
Echinococcus multilocularis sodium bile acid cotransporter 0.0388 0.2859 0.3342
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0046
Echinococcus multilocularis cysteine protease 0.0151 0.1021 0.1175
Loa Loa (eye worm) hypothetical protein 0.0051 0.024 0.0254
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.023 0.0199
Mycobacterium ulcerans beta-lactamase 0.0038 0.014 0.1653
Echinococcus multilocularis allatostatin A receptor 0.0043 0.0175 0.0178
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1114 0.8508 0.8504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Echinococcus granulosus hypothetical protein 0.0043 0.0175 0.0178
Echinococcus granulosus cysteine protease 0.0078 0.045 0.0502
Echinococcus granulosus g protein coupled receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis cathepsin L 0.0028 0.0061 0.0044
Brugia malayi Cathepsin L-like precursor 0.0101 0.0632 0.0609
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Trypanosoma brucei DNA polymerase IV, putative 0.005 0.023 0.027
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0175 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.0246
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus granulosus cathepsin b 0.0028 0.0061 0.0044
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0176 0.0298
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi fibroinase precursor 0.0028 0.0061 0.0037
Brugia malayi Ets-domain containing protein 0.0084 0.0498 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1114 0.8508 1
Echinococcus multilocularis geminin 0.0384 0.2827 0.3304
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0028 0.0061 0.1548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Brugia malayi G-protein coupled receptor 0.0043 0.0175 0.0151
Echinococcus granulosus neuropeptide receptor A26 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Echinococcus multilocularis expressed protein 0.0043 0.0176 0.0179
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Brugia malayi beta-lactamase 0.0038 0.014 0.0116
Echinococcus multilocularis orexin receptor type 2 0.0043 0.0175 0.0178
Leishmania major cathepsin L-like protease 0.0577 0.4327 0.5061
Echinococcus multilocularis thyroid hormone receptor alpha 0.1078 0.8222 0.9663
Leishmania major hypothetical protein, conserved 0.0038 0.014 0.0116
Echinococcus granulosus FTZ F1 alpha 0.0528 0.395 0.4627
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0373
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0043 0.0175 0.0151
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0298 0.0323
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0057 0.029 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Echinococcus multilocularis nuclear receptor nhr 48 0.0249 0.1781 0.2071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0528 0.395 0.4627
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0249 0.1781 0.2071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Trypanosoma cruzi cysteine peptidase, putative 0.005 0.0233 0.0203
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0028 0.0061 0.0373
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Brugia malayi ecdysteroid receptor 0.0528 0.395 0.3935
Schistosoma mansoni amine GPCR 0.0043 0.0175 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Brugia malayi steroid hormone receptor 0.0528 0.395 0.3935
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0375 0.2763 1
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.045 0.0529
Brugia malayi Steroid receptor seven-up type 2 0.0528 0.395 0.3935
Brugia malayi sodium-independent organic anion transporter family protein 0.0063 0.0331 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0528 0.395 0.3935
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus multilocularis carbonic anhydrase 0.0524 0.3914 0.4585
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0061 0.0037
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) agrin synaptic family protein 0.0043 0.0176 0.0179
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0167 1
Trypanosoma cruzi cysteine peptidase, putative 0.0151 0.1021 0.1136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Brugia malayi Cathepsin L-like precursor 0.0101 0.0632 0.0609
Brugia malayi Nuclear hormone receptor-like 1 0.1057 0.8063 0.8059
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Trypanosoma brucei unspecified product 0.0042 0.0168 0.0197
Mycobacterium leprae Probable lipase LipE 0.0038 0.014 0.5
Brugia malayi Cathepsin L-like cysteine proteinase 0.0101 0.0632 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Schistosoma mansoni hypothetical protein 0.055 0.4116 0.4823
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Echinococcus multilocularis serotonin receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0151 0.1021 0.2467
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.0632 0.6097
Echinococcus multilocularis lamin dm0 0.0058 0.0298 0.0323
Brugia malayi Sodium Bile acid symporter family protein 0.0388 0.2859 0.2842
Schistosoma mansoni opsin-like receptor 0.0043 0.0175 0.0178
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.014 0.1162
Echinococcus granulosus neuropeptide FF receptor 2 0.0043 0.0175 0.0178
Toxoplasma gondii aminopeptidase N, putative 0.0375 0.2763 0.7012
Loa Loa (eye worm) hypothetical protein 0.0151 0.1021 0.1175
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Schistosoma mansoni neuropeptide receptor 0.0043 0.0175 0.0178
Plasmodium vivax vivapain-3 0.0078 0.045 0.144
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0364 1
Loa Loa (eye worm) steroid hormone receptor 0.0528 0.395 0.4627
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0524 0.3914 0.4585
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Echinococcus multilocularis cpg binding protein 0.0037 0.0129 0.0124
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Echinococcus granulosus carbonic anhydrase 0.0524 0.3914 0.4585
Loa Loa (eye worm) hypothetical protein 0.0524 0.3914 0.4585
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.045 0.046
Trypanosoma cruzi cruzipain precursor, putative 0.0577 0.4327 0.505
Echinococcus multilocularis neuropeptide receptor A26 0.0043 0.0175 0.0178
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0151 0.1021 0.249
Brugia malayi putative neuropeptide receptor NPR1 0.0043 0.0175 0.0151
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.014 0.0579
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0063 0.0331 0.0361
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0288 0.2081 0.2424
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0122 0.0795 0.0773
Echinococcus multilocularis carbonic anhydrase 0.0524 0.3914 0.4585
Loa Loa (eye worm) fli-1 protein 0.0255 0.1827 0.2125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Schistosoma mansoni myosin xvIII 0.0043 0.0175 0.0178
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.014 0.0137
Echinococcus granulosus alpha 1A adrenergic receptor 0.0043 0.0175 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Trypanosoma cruzi cysteine protease, putative 0.0078 0.045 0.046
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0528 0.395 0.3935
Schistosoma mansoni hypothetical protein 0.0035 0.0115 0.0106
Brugia malayi cathepsin Z-like cysteine proteinase 0.0028 0.0061 0.0037
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0043 0.0175 0.0178
Brugia malayi Nuclear hormone receptor E75 0.0249 0.1781 0.1761
Onchocerca volvulus 0.0043 0.0175 0.0292
Mycobacterium tuberculosis Conserved protein 0.0038 0.014 0.0579
Schistosoma mansoni amine GPCR 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.0151 0.1021 1
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Brugia malayi hypothetical protein 0.0063 0.0331 0.0307
Brugia malayi Fli-1 protein 0.0255 0.1827 0.1808
Onchocerca volvulus 0.0038 0.014 0.0202
Echinococcus granulosus sodium bile acid cotransporter 0.0388 0.2859 0.3342
Onchocerca volvulus 0.0038 0.014 0.0202
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0175 0.0178
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0632 0.6097
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0364 0.0401
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Brugia malayi putative neuropeptide receptor 0.0043 0.0175 0.0151
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Schistosoma mansoni nuclear hormone receptor 0.0249 0.1781 0.2071
Brugia malayi cathepsin B-like cysteine proteinase 0.0028 0.0061 0.0037
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0364 0.0401
Brugia malayi tailless protein 0.0249 0.1781 0.1761
Brugia malayi Nuclear hormone receptor E75 0.0249 0.1781 0.1761
Brugia malayi RE15519p 0.0043 0.0175 0.0151
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Schistosoma mansoni carbonic anhydrase 0.0524 0.3914 0.4585
Onchocerca volvulus 0.0043 0.0175 0.0292
Entamoeba histolytica hypothetical protein 0.0028 0.0061 0.0373
Schistosoma mansoni histamine h1 receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis sex peptide receptor 0.0043 0.0175 0.0178
Echinococcus granulosus follistatin 0.0043 0.0176 0.0179
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0043 0.0175 0.0178
Brugia malayi neuropeptide F receptor 0.0043 0.0175 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Echinococcus granulosus dnaJ subfamily B 0.0494 0.3684 0.4314
Schistosoma mansoni sodium-bile acid cotransporter 0.0147 0.0987 0.1135
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.014 0.0579
Echinococcus granulosus cathepsin l cysteine peptidase 0.0151 0.1021 0.1175
Plasmodium vivax vivapain-2 0.0151 0.1021 0.3551
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) melatonin receptor type 1A 0.0043 0.0175 0.0178
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.014 0.0093
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Schistosoma mansoni cathepsin C 0.0028 0.0061 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0175 0.0178
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0028 0.0061 0.0044
Onchocerca volvulus 0.0043 0.0175 0.0292
Schistosoma mansoni cpg binding protein 0.0037 0.0129 0.0124
Schistosoma mansoni nuclear receptor nhr-48 0.0249 0.1781 0.2071
Mycobacterium ulcerans DNA polymerase IV 0.005 0.023 0.4997
Schistosoma mansoni lamin 0.0058 0.0298 0.0323
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Brugia malayi hypothetical protein 0.0063 0.0331 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0167 0.0168
Echinococcus multilocularis carbonic anhydrase II 0.1114 0.8508 1
Onchocerca volvulus 0.0043 0.0175 0.0292
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus granulosus cathepsin L cysteine proteinase 0.0151 0.1021 0.1175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0084 0.0498 0.0558
Toxoplasma gondii aminopeptidase n, putative 0.0375 0.2763 0.7012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0063 0.0046
Schistosoma mansoni organic anion transporter 0.0063 0.0331 0.0361
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Echinococcus granulosus ecdysone induced protein 78C 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.005 0.023 0.2063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Giardia lamblia Cysteine protease 0.0028 0.0061 0.1548
Schistosoma mansoni adenoreceptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0043 0.0175 0.0178
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.014 0.1653
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0028 0.0061 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0167 0.0196
Onchocerca volvulus 0.0058 0.0298 0.0609
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.014 0.1162
Schistosoma mansoni neuropeptide receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0119 0.0112
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0176 0.0152
Brugia malayi beta-lactamase family protein 0.0038 0.014 0.0116
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0528 0.395 0.4627
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Brugia malayi nuclear receptor RXR 0.0279 0.2013 0.1994
Brugia malayi nuclear hormone receptor family member odr-7 0.0249 0.1781 0.1761
Echinococcus multilocularis fmrfamide receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis neuropeptide FF receptor 2 0.0043 0.0175 0.0178
Trypanosoma cruzi cruzipain precursor, putative 0.005 0.0233 0.0203
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0043 0.0175 0.0178
Echinococcus multilocularis lamin 0.0058 0.0298 0.0323
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Plasmodium vivax vivapain-1 0.0078 0.045 0.144
Echinococcus multilocularis somatostatin receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Leishmania major cathepsin L-like protease 0.0151 0.1021 0.1156
Echinococcus multilocularis cathepsin L 0.0078 0.045 0.0502
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0061 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0078 0.045 0.4276
Schistosoma mansoni amine GPCR 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0167 0.0168
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.014 0.0137
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.014 0.0137
Schistosoma mansoni amine GPCR 0.0043 0.0175 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0176 0.0152
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Echinococcus granulosus 7tm_1 domain containing protein 0.0043 0.0175 0.0178
Giardia lamblia Hypothetical protein 0.0028 0.0061 0.1548
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0175 0.0178
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Schistosoma mansoni cpg binding protein 0.0035 0.0114 0.0106
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.014 0.0579
Leishmania major cytochrome p450-like protein 0.0032 0.0096 0.0063
Echinococcus granulosus cathepsin b 0.0028 0.0061 0.0044
Plasmodium falciparum cysteine proteinase falcipain 3 0.0151 0.1021 0.249
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0088 0.0063
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.023 0.0199
Plasmodium vivax unspecified product 0.0078 0.045 0.144
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0043 0.0176 0.0152
Echinococcus granulosus orexin receptor type 2 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0038 0.014 0.0202
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0249 0.1781 0.2071
Schistosoma mansoni ets-related 0.0255 0.1827 0.2125
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.023 0.0199
Trypanosoma cruzi DNA polymerase kappa, putative 0.005 0.023 0.0199
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0249 0.1781 0.2071
Echinococcus multilocularis follistatin 0.0043 0.0176 0.0179
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0061 0.0044
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0279 0.2013 0.2345
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0136 0.016
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0043 0.0175 0.0292
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0028 0.0061 0.1548
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Schistosoma mansoni carbonic anhydrase-related 0.0524 0.3914 0.4585
Toxoplasma gondii ABC1 family protein 0.0038 0.014 0.0204
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0524 0.3914 0.3899
Echinococcus granulosus sodium bile acid cotransporter 0.0388 0.2859 0.3342
Onchocerca volvulus Putative organic anion transporter 0.0063 0.0331 0.0692
Loa Loa (eye worm) hypothetical protein 0.0524 0.3914 0.4585
Brugia malayi Cathepsin L-like precursor 0.005 0.0233 0.021
Onchocerca volvulus Bile acid receptor homolog 0.0528 0.395 1
Echinococcus granulosus nuclear receptor nhr 48 0.0249 0.1781 0.2071
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0036
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0114 0.0106
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0249 0.1781 0.2071
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.014 0.0137
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0063 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Loa Loa (eye worm) nuclear hormone receptor 0.0249 0.1781 0.2071
Onchocerca volvulus 0.0063 0.0331 0.0692
Echinococcus granulosus 7TM GPCR rhodopsin 0.0043 0.0175 0.0178
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0096 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.1027 0.7831 0.9202
Loa Loa (eye worm) hypothetical protein 0.0101 0.0632 0.0716
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Echinococcus multilocularis G-protein coupled receptor, putative 0.0043 0.0175 0.0178
Trypanosoma cruzi major cysteine proteinase, putative 0.0453 0.3368 0.3914
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0373
Brugia malayi nuclear hormone receptor family member nhr-6 0.0249 0.1781 0.1761
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0088 0.0075
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0043 0.0175 0.0178
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0298 0.0323
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Trypanosoma cruzi cysteine proteinase, putative 0.0078 0.045 0.046
Schistosoma mansoni lamin 0.0058 0.0298 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0167 0.143
Toxoplasma gondii transporter, major facilitator family protein 0.0063 0.0331 0.0699
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Schistosoma mansoni amine GPCR 0.0043 0.0175 0.0178
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0167 0.0125
Leishmania major cathepsin L-like protease 0.0151 0.1021 0.1156
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0527 0.3938 0.4589
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0063 0.0331 0.0361
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0063 0.0331 0.0361
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0528 0.395 0.4627
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0028 0.0061 0.0044
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Onchocerca volvulus 0.0151 0.1021 0.2467
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0175 0.0178
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0279 0.2013 0.2345
Schistosoma mansoni nuclear receptor 0.0249 0.1781 0.2071
Entamoeba histolytica cysteine proteinase 2 0.0078 0.045 0.4276
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Brugia malayi hypothetical protein 0.0249 0.1781 0.1761
Echinococcus granulosus cathepsin L cysteine protease 0.0078 0.045 0.0502
Brugia malayi Cytochrome P450 family protein 0.0032 0.0096 0.0072
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0288 0.2081 0.2424
Loa Loa (eye worm) DR-78 0.0249 0.1781 0.2071
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0063 0.0331 0.0692
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1734 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0078 0.045 0.4276
Brugia malayi cathepsin L precursor 0.0028 0.0061 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0577 0.4327 0.505
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Echinococcus granulosus peptide allatostatin:somatostatin 0.0043 0.0175 0.0178
Giardia lamblia Cathepsin L precursor 0.0028 0.0061 0.1548
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Brugia malayi sodium-independent organic anion transporter family protein 0.0063 0.0331 0.0307
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0524 0.3914 0.3899
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0524 0.3914 0.3899
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Echinococcus granulosus g protein coupled receptor 0.0043 0.0175 0.0178
Brugia malayi Dopamine receptor protein 1 0.0043 0.0175 0.0151
Schistosoma mansoni thyroid hormone receptor 0.1078 0.8222 0.9663
Brugia malayi beta-lactamase family protein 0.0038 0.014 0.0116
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0035 0.0115 0.0106
Echinococcus multilocularis cathepsin b 0.0028 0.0061 0.0044
Loa Loa (eye worm) carbonic anhydrase 3 0.1114 0.8508 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0249 0.1781 0.1761
Loa Loa (eye worm) hypothetical protein 0.0072 0.0403 0.0446
Leishmania major cathepsin L-like protease 0.0151 0.1021 0.1156
Onchocerca volvulus 0.0043 0.0175 0.0292
Schistosoma mansoni cathepsin F (C01 family) 0.0151 0.1021 0.1175
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0043 0.0175 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0528 0.395 0.4627
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Echinococcus multilocularis sodium bile acid cotransporter 0.0388 0.2859 0.3342
Giardia lamblia Cathepsin L-like protease 0.0028 0.0061 0.1548
Trypanosoma cruzi MFS transporter, putative 0.0063 0.0331 0.0319
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus granulosus agrin 0.0043 0.0176 0.0179
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0528 0.395 0.4627
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Echinococcus granulosus tm gpcr rhodopsin 0.0043 0.0175 0.0178
Brugia malayi cathepsin F-like cysteine proteinase 0.0028 0.0061 0.0037
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Onchocerca volvulus 0.0151 0.1021 0.2467
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0249 0.1781 0.2071
Brugia malayi conserved hypotetical protein 0.0249 0.1781 0.1761
Schistosoma mansoni hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0028 0.0061 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0167 0.143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Onchocerca volvulus 0.0151 0.1021 0.2467
Echinococcus granulosus cpg binding protein 0.0037 0.0129 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0028 0.0061 0.0373
Mycobacterium leprae conserved hypothetical protein 0.0038 0.014 0.5
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.005 0.0233 0.021
Trypanosoma cruzi cysteine peptidase, putative 0.0577 0.4327 0.505
Echinococcus multilocularis dna polymerase kappa 0.005 0.023 0.0242
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0249 0.1781 0.4422
Echinococcus granulosus neuropeptide s receptor 0.0043 0.0175 0.0178
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0038 0.014 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0528 0.395 0.3935
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0028 0.0061 0.0037
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0528 0.395 0.4627
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0078 0.045 0.0502
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni sodium-bile acid cotransporter related 0.0241 0.1716 0.1994
Echinococcus multilocularis expressed protein 0.0451 0.3348 0.3918
Echinococcus granulosus neuropeptide receptor 0.0043 0.0175 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Loa Loa (eye worm) TYRA-2 protein 0.0043 0.0175 0.0178
Toxoplasma gondii cathepsin CPL 0.0151 0.1021 0.249
Loa Loa (eye worm) G-protein coupled receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Brugia malayi cathepsin L-like cysteine proteinase 0.0028 0.0061 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0298 0.0275
Loa Loa (eye worm) hypothetical protein 0.0524 0.3914 0.4585
Plasmodium vivax hypothetical protein, conserved 0.0038 0.014 0.0291
Loa Loa (eye worm) fibroinase 0.0151 0.1021 0.1175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine protease, putative 0.0078 0.045 0.4276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Trypanosoma cruzi cysteine peptidase, putative 0.0577 0.4327 0.505
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.024 0.0254
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0528 0.395 0.4627
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0028 0.0061 0.1548
Schistosoma mansoni intermediate filament proteins 0.0058 0.0298 0.0323
Echinococcus granulosus carbonic anhydrase II 0.1114 0.8508 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0528 0.395 0.4627
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.014 0.1162
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0528 0.395 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Schistosoma mansoni carbonic anhydrase-related 0.0524 0.3914 0.4585
Schistosoma mansoni hypothetical protein 0.0384 0.2827 0.3304
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0078 0.045 0.046
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0043 0.0175 0.0178
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0151 0.1021 0.1175
Echinococcus multilocularis G protein coupled receptor 139 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Onchocerca volvulus 0.0528 0.395 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0028 0.0061 0.0072
Loa Loa (eye worm) hypothetical protein 0.0101 0.0632 0.0716
Plasmodium falciparum carbonic anhydrase 0.0524 0.3914 1
Schistosoma mansoni biogenic amine receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0043 0.0175 0.0178
Mycobacterium tuberculosis Conserved protein 0.0038 0.014 0.0579
Brugia malayi sodium-independent organic anion transporter family protein 0.0063 0.0331 0.0307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Brugia malayi Tachykinin-like peptides receptor 99D 0.0043 0.0175 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.045 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0028 0.0061 0.0373
Entamoeba histolytica cysteine proteinase, putative 0.0151 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0078 0.045 0.0502
Onchocerca volvulus 0.0043 0.0175 0.0292
Schistosoma mansoni hypothetical protein 0.0055 0.0271 0.029
Onchocerca volvulus Cathepsin L homolog 0.0151 0.1021 0.2467
Echinococcus multilocularis agrin 0.0043 0.0176 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0028 0.0061 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0249 0.1781 0.2071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Brugia malayi Papain family cysteine protease containing protein 0.0078 0.045 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Loa Loa (eye worm) hypothetical protein 0.0101 0.0632 0.0716
Brugia malayi photoreceptor-specific nuclear receptor 0.0528 0.395 0.3935
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0528 0.395 0.3935
Leishmania major cathepsin L-like protease 0.0577 0.4327 0.5061
Brugia malayi sulfakinin receptor protein 0.0043 0.0175 0.0151
Brugia malayi intermediate filament protein 0.0058 0.0298 0.0275
Loa Loa (eye worm) hypothetical protein 0.0279 0.2013 0.2345
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0168 0.0197
Onchocerca volvulus 0.0063 0.0331 0.0692
Echinococcus multilocularis sodium bile acid cotransporter 0.0388 0.2859 0.3342
Echinococcus granulosus intermediate filament protein 0.0058 0.0298 0.0323
Echinococcus granulosus dna polymerase kappa 0.005 0.023 0.0242
Loa Loa (eye worm) hypothetical protein 0.0388 0.2859 0.3342
Echinococcus granulosus cathepsin l1 0.0151 0.1021 0.1175
Onchocerca volvulus 0.0151 0.1021 0.2467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0043 0.0175 0.0178
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.014 0.0579
Onchocerca volvulus 0.0035 0.0114 0.0135
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0528 0.395 0.4627
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0151 0.1021 0.2467
Brugia malayi Papain family cysteine protease containing protein 0.0151 0.1021 0.0999
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi G protein-coupled receptor 0.0043 0.0175 0.0151
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Echinococcus granulosus carbonic anhydrase 0.0524 0.3914 0.4585
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Schistosoma mansoni sodium-bile acid cotransporter related 0.0388 0.2859 0.3342
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Echinococcus granulosus G protein coupled receptor 139 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi Ets-domain containing protein 0.0084 0.0498 0.0474
Brugia malayi cathepsin L-like precursor 0.0101 0.0632 0.0609
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0043 0.0175 0.0292
Mycobacterium ulcerans lipase LipD 0.0038 0.014 0.1653
Loa Loa (eye worm) hypothetical protein 0.0043 0.0176 0.0179
Loa Loa (eye worm) neuropeptide F receptor 0.0043 0.0175 0.0178
Leishmania major cysteine peptidase A (CPA) 0.0151 0.1021 0.1156
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Schistosoma mansoni cathepsin S (C01 family) 0.0028 0.0061 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi nuclear receptor RXR 0.0249 0.1781 0.1761
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0043 0.0175 0.0178
Schistosoma mansoni organic anion transporter 0.0063 0.0331 0.0361
Schistosoma mansoni biogenic amine receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0279 0.2013 0.2345
Onchocerca volvulus 0.0249 0.1781 0.4422
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0043 0.0175 0.0292
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0528 0.395 0.4627
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0028 0.0061 0.0373
Echinococcus multilocularis FTZ F1 alpha 0.0528 0.395 0.4627
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.0061 0.0044
Onchocerca volvulus Protein ultraspiracle homolog 0.0528 0.395 1
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0524 0.3914 0.3899
Echinococcus granulosus tachykinin peptides receptor 99D 0.0043 0.0175 0.0178
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0096 0.0084
Echinococcus granulosus Solute carrier organic anion transporter family 0.0063 0.0331 0.0361
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0528 0.395 0.3935
Onchocerca volvulus 0.0063 0.0331 0.0692
Brugia malayi orphan nuclear receptor NR2E1 0.0249 0.1781 0.1761
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0528 0.395 0.4627
Brugia malayi secreted modular calcium-binding protein 1 0.0043 0.0176 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Onchocerca volvulus 0.0063 0.0331 0.0692
Echinococcus granulosus Nuclear hormone receptor HR96 0.0249 0.1781 0.2071
Loa Loa (eye worm) hypothetical protein 0.0528 0.395 0.4627
Schistosoma mansoni hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi Nuclear hormone receptor-like 1 0.1057 0.8063 0.8059
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0176 0.0298
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0043 0.0175 0.0178
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Plasmodium vivax vivapain-2 0.0151 0.1021 0.3551
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Schistosoma mansoni hypothetical protein 0.0494 0.3684 0.4314
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0043 0.0175 0.0178
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0028 0.0061 0.0373
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.0061 0.0373
Loa Loa (eye worm) hypothetical protein 0.0043 0.0176 0.0179
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0043 0.0175 0.0178
Echinococcus multilocularis musashi 0.0058 0.0298 0.0323
Brugia malayi Papain family cysteine protease containing protein 0.0078 0.045 0.0427
Brugia malayi hypothetical protein 0.0043 0.0175 0.0151
Brugia malayi cathepsin F-like cysteine proteinase 0.005 0.0233 0.021
Schistosoma mansoni cpg binding protein 0.0037 0.0129 0.0124
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0028 0.0061 0.0373
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.055 0.4116 0.4823
Echinococcus granulosus cathepsin L 0.0028 0.0061 0.0044
Brugia malayi Cytochrome P450 family protein 0.0035 0.0119 0.0095
Loa Loa (eye worm) cysteine protease 0.0151 0.1021 0.1175
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Echinococcus multilocularis cathepsin L cysteine protease 0.0151 0.1021 0.1175
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0375 0.2763 0.7012
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0136 0.016
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0167 0.143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.1021 1
Loa Loa (eye worm) ctsf protein 0.0151 0.1021 0.1175
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.3684 0.4314
Echinococcus granulosus allatostatin A receptor 0.0043 0.0175 0.0178
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0043 0.0175 0.0178
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.0061 0.0037
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0167 0.0168
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0528 0.395 0.4627
Echinococcus granulosus biogenic amine 5HT receptor 0.0043 0.0175 0.0178
Echinococcus granulosus dro:myosuppressin receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) hypothetical protein 0.0028 0.0061 0.0044
Loa Loa (eye worm) hypothetical protein 0.005 0.0233 0.0246
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.014 0.1653
Echinococcus multilocularis cysteine protease 0.0151 0.1021 0.1175
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0167 0.0168
Leishmania major carbonic anhydrase-like protein 0.1114 0.8508 1
Echinococcus granulosus fmrfamide receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) nuclear receptor NHR-67 0.0249 0.1781 0.2071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Toxoplasma gondii aminopeptidase N protein 0.0375 0.2763 0.7012
Echinococcus granulosus carbonic anhydrase 0.0524 0.3914 0.4585
Loa Loa (eye worm) hypothetical protein 0.0041 0.0167 0.0168
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0028 0.0061 0.0023
Schistosoma mansoni hypothetical protein 0.0524 0.3914 0.4585
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0305 0.2216 0.2583
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0096 0.0041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.014 0.0137
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0279 0.2013 0.2345
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0063 0.0331 0.0361
Onchocerca volvulus 0.0058 0.0298 0.0609
Giardia lamblia Cathepsin B precursor 0.0028 0.0061 0.1548
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0151 0.1021 1
Entamoeba histolytica cysteine protease, putative 0.0151 0.1021 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0577 0.4327 0.5086
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0043 0.0175 0.0178
Giardia lamblia Encystation-specific protease 0.0028 0.0061 0.1548
Brugia malayi Cathepsin L-like precursor 0.0151 0.1021 0.0999
Echinococcus granulosus neuropeptide Y receptor 0.0043 0.0175 0.0178
Loa Loa (eye worm) papain family cysteine protease containing protein 0.005 0.0233 0.0246
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0151 0.1021 0.249
Brugia malayi nuclear receptor NHR-88 0.0528 0.395 0.3935
Schistosoma mansoni RAR-like nuclear receptor 0.0528 0.395 0.4627
Brugia malayi Serotonin receptor 0.0043 0.0175 0.0151
Loa Loa (eye worm) hypothetical protein 0.0122 0.0795 0.0909
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0061 0.0373
Schistosoma mansoni nuclear hormone receptor 0.0528 0.395 0.4627
Echinococcus granulosus rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0364 0.1903
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.024 0.0216
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Brugia malayi cathepsin Z-like cysteine proteinase 0.0028 0.0061 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0528 0.395 0.3935
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0043 0.0175 0.0178
Mycobacterium tuberculosis Conserved protein 0.0038 0.014 0.0579
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0364 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0028 0.0061 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0028 0.0061 0.0373
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0028 0.0061 0.0373
Mycobacterium ulcerans DNA polymerase IV 0.005 0.023 0.4997
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.1021 1
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0528 0.395 0.4627
Onchocerca volvulus 0.0043 0.0175 0.0292
Echinococcus granulosus expressed protein 0.0451 0.3348 0.3918
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0528 0.395 0.4627
Onchocerca volvulus Putative organic anion transporter 0.0063 0.0331 0.0692
Echinococcus multilocularis neuropeptide s receptor 0.0043 0.0175 0.0178
Echinococcus granulosus neuropeptides capa receptor 0.0043 0.0175 0.0178
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0043 0.0175 0.0151
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0167 0.0147
Echinococcus multilocularis dro:myosuppressin receptor 0.0043 0.0175 0.0178
Entamoeba histolytica cysteine proteinase, putative 0.0078 0.045 0.4276
Echinococcus multilocularis neuropeptide Y receptor 0.0043 0.0175 0.0178
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0416 0.0462
Entamoeba histolytica cysteine protease, putative 0.0028 0.0061 0.0373
Giardia lamblia Cysteine protease 0.0028 0.0061 0.1548
Schistosoma mansoni hypothetical protein 0.0384 0.2827 0.3304
Loa Loa (eye worm) hypothetical protein 0.0063 0.0331 0.0361
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.014 0.0579
Schistosoma mansoni neuropeptide f receptor 76f 0.0043 0.0175 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.023 0.027
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Echinococcus granulosus geminin 0.0384 0.2827 0.3304
Brugia malayi hypothetical protein 0.0279 0.2013 0.1994
Loa Loa (eye worm) beta-lactamase 0.0038 0.014 0.0137
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1114 0.8508 0.8504
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0528 0.395 0.4627
Echinococcus multilocularis ecdysone induced protein 78C 0.0528 0.395 0.4627
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.0061 0.0373
Loa Loa (eye worm) hypothetical protein 0.0249 0.1781 0.2071
Plasmodium falciparum cysteine proteinase falcipain 1 0.0078 0.045 0.101
Schistosoma mansoni neuropeptide receptor 0.0043 0.0175 0.0178
Schistosoma mansoni neuropeptide receptor 0.0043 0.0175 0.0178
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1114 0.8508 1
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.014 0.0165
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.024 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0028 0.0061 0.0373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0043 0.0175 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0043 0.0175 0.0178
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0043 0.0175 0.0178
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.014 0.1162
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0043 0.0176 0.0179
Brugia malayi hypothetical protein 0.0279 0.2013 0.1994
Leishmania major cathepsin L-like protease 0.0151 0.1021 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0151 0.1021 1
Trichomonas vaginalis DNA polymerase eta, putative 0.005 0.023 0.2063
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0028 0.0061 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0528 0.395 0.3935
Echinococcus multilocularis cathepsin L cysteine protease 0.0151 0.1021 0.1175
Brugia malayi AKH receptor 0.0043 0.0175 0.0151
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0528 0.395 0.4627
Loa Loa (eye worm) hypothetical protein 0.0279 0.2013 0.2345
Echinococcus granulosus sodium bile acid cotransporter 0.0388 0.2859 0.3342
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0167 0.0168
Onchocerca volvulus 0.0043 0.0175 0.0292
Giardia lamblia Hypothetical protein 0.0028 0.0061 0.1548
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0043 0.0175 0.0178
Onchocerca volvulus Cathepsin L homolog 0.0151 0.1021 0.2467
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0249 0.1781 0.2071
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.014 0.0116
Schistosoma mansoni biogenic amine (5HT) receptor 0.0043 0.0175 0.0178
Brugia malayi G-protein coupled receptor 0.0043 0.0175 0.0151

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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