Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4458 | 0.4458 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0045 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.4622 | 0.4622 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0045 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 1 | 0.5 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0045 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 1 | 1 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0045 | 1 | 0.5 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0045 | 1 | 1 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0045 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.4622 | 0.4354 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.4622 | 0.4354 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0045 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0028 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.4622 | 0.4622 |
Onchocerca volvulus | 0.0028 | 0.4622 | 0.5 | |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0045 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0045 | 1 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.4622 | 0.4622 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0045 | 1 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Echinococcus multilocularis | musashi | 0.0028 | 0.4622 | 0.4622 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.4622 | 0.4622 |
Echinococcus multilocularis | lamin | 0.0028 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.4622 | 0.4622 |
Onchocerca volvulus | 0.0028 | 0.4622 | 0.5 | |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0474 | 0.0474 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0045 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0045 | 1 | 0.5 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0045 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.