Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0045 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.4622 | 0.4354 |
Echinococcus granulosus | lamin | 0.0028 | 0.4622 | 0.4622 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.4622 | 0.4622 |
Echinococcus multilocularis | musashi | 0.0028 | 0.4622 | 0.4622 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0045 | 1 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.4622 | 0.4622 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Onchocerca volvulus | 0.0028 | 0.4622 | 0.5 | |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0045 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4622 | 0.4622 |
Onchocerca volvulus | 0.0028 | 0.4622 | 0.5 | |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.4622 | 0.4622 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0045 | 1 | 1 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0045 | 1 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0045 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 1 | 0.5 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0045 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0045 | 1 | 0.5 |
Echinococcus multilocularis | lamin | 0.0028 | 0.4622 | 0.4622 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.4622 | 0.4354 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0045 | 1 | 0.5 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0045 | 1 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0474 | 0.0474 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0045 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.4458 | 0.4458 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0045 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.4622 | 0.4622 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0045 | 1 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0045 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.