TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 258.276 | Formula: C13H14N4O2
H donors: 1 H acceptors: 3 LogP: 0.25 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: CNc1nnc2c(c1)CN(CC2)C(=O)c1cocc1
InChi: 1S/C13H14N4O2/c1-14-12-6-10-7-17(4-2-11(10)15-16-12)13(18)9-3-5-19-8-9/h3,5-6,8H,2,4,7H2,1H3,(H,14,16)
InChiKey: YGLLAINVOHZJOK-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Chlamydia trachomatis	neutral amino acid transporter	0.0092	0.1613	0.4046
Echinococcus granulosus	voltage dependent calcium channel	0.0021	0.0144	0.0184
Schistosoma mansoni	integrin alpha	0.0031	0.0355	0.0575
Schistosoma mansoni	hypothetical protein	0.0019	0.0109	0.0177
Plasmodium falciparum	amino acid transporter, putative	0.0014	0	0.5
Echinococcus multilocularis	integrin alpha ps	0.0015	0.0026	0.0033
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.003	0.0345	0.5
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0076	0.0076
Brugia malayi	EGF-like domain containing protein	0.0017	0.0076	0.0076
Schistosoma mansoni	high voltage-activated calcium channel Cav1	0.0059	0.093	0.1507
Echinococcus granulosus	Excitatory amino acid transporter	0.0209	0.3986	0.5088
Brugia malayi	hypothetical protein	0.007	0.1155	0.1155
Echinococcus granulosus	integrin alpha ps	0.0015	0.0026	0.0033
Brugia malayi	hypothetical protein	0.0081	0.1387	0.1387
Toxoplasma gondii	hypothetical protein	0.0018	0.0093	0.1469
Echinococcus multilocularis	microsomal glutathione S transferase 3	0.0045	0.0634	0.0809
Brugia malayi	Integrin alpha cytoplasmic region family protein	0.0015	0.0026	0.0026
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0023	0.0196	0.0196
Echinococcus granulosus	geminin	0.0079	0.1328	0.1696
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0046	0.0046
Echinococcus granulosus	sterol regulatory element binding protein	0.002	0.0124	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0144	0.0144
Echinococcus granulosus	excitatory amino acid transporter 2	0.0209	0.3986	0.5088
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0093	0.0093
Schistosoma mansoni	hypothetical protein	0.0079	0.1328	0.2153
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0017	0.0064	0.0082
Brugia malayi	gamma-secretase subunit aph-1	0.0184	0.3489	0.3489
Echinococcus multilocularis	fibrillin 2	0.0017	0.0076	0.0098
Brugia malayi	Integrin alpha pat-2 precursor	0.0031	0.0355	0.0355
Echinococcus granulosus	expressed conserved protein	0.0043	0.0599	0.0765
Trypanosoma cruzi	Aph-1 protein, putative	0.0072	0.1191	1
Echinococcus multilocularis	integrin alpha 3	0.0015	0.0026	0.0033
Echinococcus multilocularis	excitatory amino acid transporter 2	0.0209	0.3986	0.5088
Brugia malayi	latrophilin 2 splice variant baaae	0.0016	0.0046	0.0046
Brugia malayi	Excitatory amino acid transporter	0.0209	0.3986	0.3986
Mycobacterium ulcerans	aldehyde dehydrogenase	0.003	0.0345	0.5
Loa Loa (eye worm)	kelch domain-containing protein family protein	0.0081	0.1387	0.1387
Echinococcus multilocularis	neutral amino acid transporter excitatory amino acid transporter	0.0209	0.3986	0.5088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0024	0.0215	0.0275
Echinococcus multilocularis	neutral amino acid transporter A	0.0209	0.3986	0.5088
Giardia lamblia	Tenascin-37	0.0017	0.0076	0.5
Schistosoma mansoni	hypothetical protein	0.0016	0.0046	0.0075
Toxoplasma gondii	aldehyde dehydrogenase	0.003	0.0345	0.5445
Loa Loa (eye worm)	transcription factor SMAD2	0.0055	0.0854	0.0854
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0059	0.093	0.1187
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.0048	0.0706	0.09
Giardia lamblia	High cysteine protein	0.0017	0.0076	0.5
Treponema pallidum	glutamate transporter	0.0092	0.1613	1
Echinococcus multilocularis	integrin alpha ps	0.0031	0.0355	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0093	0.0093
Echinococcus granulosus	fibrillin 1	0.0017	0.0076	0.0098
Echinococcus granulosus	excitatory amino acid transporter 2	0.0209	0.3986	0.5088
Onchocerca volvulus		0.007	0.1155	0.2897
Echinococcus multilocularis	neutral amino acid transporter excitatory amino acid transporter	0.0092	0.1613	0.2059
Schistosoma mansoni	voltage-gated cation channel	0.0059	0.093	0.1507
Schistosoma mansoni	jumonji domain containing protein	0.0035	0.0442	0.0716
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0197	0.0197
Schistosoma mansoni	hypothetical protein	0.0019	0.0109	0.0177
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0044	0.0628	0.0801
Loa Loa (eye worm)	hypothetical protein	0.005	0.0736	0.0736
Echinococcus granulosus	adam	0.0017	0.0076	0.0098
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.003	0.0345	0.044
Onchocerca volvulus		0.0017	0.0076	0.0192
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Echinococcus multilocularis	expressed conserved protein	0.0043	0.0599	0.0765
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0052	0.0052
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0046	0.067	0.1086
Echinococcus multilocularis	gamma secretase subunit aph 1	0.0184	0.3489	0.4453
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0196	0.0196
Schistosoma mansoni	high voltage-activated calcium channel Cav2A	0.0059	0.093	0.1507
Giardia lamblia	Neurogenic locus notch-like protein	0.0017	0.0076	0.5
Schistosoma mansoni	hypothetical protein	0.0079	0.1328	0.2153
Plasmodium vivax	hypothetical protein, conserved	0.0014	0	0.5
Schistosoma mansoni	integrin alpha-ps	0.0016	0.0052	0.0085
Schistosoma mansoni	sodium/chloride dependent transporter	0.005	0.0736	0.1193
Brugia malayi	EGF-like domain containing protein	0.0017	0.0076	0.0076
Echinococcus multilocularis	neutral amino acid transporter A	0.0209	0.3986	0.5088
Toxoplasma gondii	MAPEG family protein	0.0045	0.0634	1
Loa Loa (eye worm)	solute carrier family 6 member 4	0.005	0.0736	0.0736
Giardia lamblia	High cysteine protein	0.0017	0.0076	0.5
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.003	0.0345	0.044
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0016	0.0058	0.0094
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0024	0.0215	0.0275
Echinococcus granulosus	jumonji domain containing protein	0.0019	0.0108	0.0138
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0024	0.0215	0.0349
Echinococcus multilocularis	Niemann Pick C1 protein	0.0046	0.0656	0.0837
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0706	0.0706
Echinococcus multilocularis	serotonin transporter	0.005	0.0736	0.094
Brugia malayi	jmjC domain containing protein	0.0044	0.0628	0.0628
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.0046	0.0656	1
Echinococcus multilocularis	voltage dependent calcium channel	0.0059	0.093	0.1187
Schistosoma mansoni	hypothetical protein	0.0019	0.0109	0.0177
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0076	0.0076
Echinococcus multilocularis	adam	0.0017	0.0076	0.0098
Giardia lamblia	hypothetical protein	0.0017	0.0076	0.5
Echinococcus multilocularis	neutral amino acid transporter A	0.0209	0.3986	0.5088
Echinococcus granulosus	neutral amino acid transporter A	0.0209	0.3986	0.5088
Loa Loa (eye worm)	hypothetical protein	0.005	0.0736	0.0736
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0024	0.0215	0.0215
Loa Loa (eye worm)	integrin alpha pat-2	0.0031	0.0355	0.0355
Echinococcus granulosus	serotonin transporter	0.005	0.0736	0.094
Echinococcus multilocularis	Excitatory amino acid transporter	0.0209	0.3986	0.5088
Echinococcus granulosus	voltage dependent L type calcium channel subunit\|voltage dependent calcium channel	0.0059	0.093	0.1187
Loa Loa (eye worm)	norepinephrine transporter	0.005	0.0736	0.0736
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.005	0.0736	0.0736
Loa Loa (eye worm)	jmjC domain-containing protein	0.0028	0.0294	0.0294
Echinococcus granulosus	integrin alpha ps	0.0031	0.0355	0.0453
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0052	0.0052
Mycobacterium tuberculosis	Probable C4-dicarboxylate-transport transmembrane protein DctA	0.0209	0.3986	1
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Loa Loa (eye worm)	hypothetical protein	0.0081	0.1387	0.1387
Mycobacterium ulcerans	aldehyde dehydrogenase	0.003	0.0345	0.5
Brugia malayi	jmjC domain containing protein	0.0016	0.0058	0.0058
Schistosoma mansoni	sodium/dicarboxylate symporter-related	0.0092	0.1613	0.2614
Echinococcus multilocularis	voltage dependent calcium channel	0.0059	0.093	0.1187
Giardia lamblia	Neurogenic locus Notch protein precursor	0.0017	0.0076	0.5
Schistosoma mansoni	gamma-secretase subunit aph-1	0.0184	0.3489	0.5653
Loa Loa (eye worm)	excitatory amino acid transporter	0.0209	0.3986	0.3986
Trypanosoma cruzi	Aph-1 protein, putative	0.0072	0.1191	1
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.005	0.0736	0.1193
Echinococcus multilocularis	Niemann Pick C1 protein	0.0065	0.1056	0.1348
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0024	0.0215	0.0275
Echinococcus multilocularis	integrin alpha ps	0.0031	0.0355	0.0453
Giardia lamblia	Tenascin-like	0.0017	0.0076	0.5
Echinococcus multilocularis	excitatory amino acid transporter 2	0.0209	0.3986	0.5088
Brugia malayi	Niemann-Pick C1 protein precursor	0.0046	0.0656	0.0656
Trichomonas vaginalis	conserved hypothetical protein	0.002	0.0124	0.035
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0048	0.0706	0.1143
Echinococcus granulosus	integrin alpha 3	0.0015	0.0026	0.0033
Echinococcus granulosus	neutral amino acid transporter A	0.0209	0.3986	0.5088
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0376	0.7404	0.945
Loa Loa (eye worm)	hypothetical protein	0.007	0.1155	0.1155
Echinococcus multilocularis	protein patched	0.002	0.0124	0.0158
Echinococcus multilocularis	integrin beta 2	0.0397	0.7835	1
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0048	0.0706	0.1143
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0024	0.0215	0.0275
Echinococcus granulosus	Niemann Pick C1 protein	0.0065	0.1056	0.1348
Schistosoma mansoni	hypothetical protein	0.0015	0.0026	0.0042
Echinococcus granulosus	integrin beta 2	0.0397	0.7835	1
Onchocerca volvulus		0.005	0.0736	0.1847
Brugia malayi	MH2 domain containing protein	0.0055	0.0854	0.0854
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.0059	0.093	0.1187
Treponema pallidum	glutamate/aspartate transporter	0.0092	0.1613	1
Schistosoma mansoni	integrin alpha-4	0.0132	0.2423	0.3927
Echinococcus multilocularis	fibrillin 1	0.0017	0.0076	0.0098
Mycobacterium ulcerans	aldehyde dehydrogenase	0.003	0.0345	0.5
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0059	0.093	0.1187
Brugia malayi	CHE-14 protein	0.002	0.0124	0.0124
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0024	0.0215	0.0349
Brugia malayi	EGF-like domain containing protein	0.0017	0.0076	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0656	0.0656
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0076	0.0076
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0706	0.0706
Echinococcus multilocularis	sterol regulatory element binding protein	0.002	0.0124	0.0158
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0024	0.0215	0.0349
Loa Loa (eye worm)	jmjC domain-containing protein	0.0016	0.0058	0.0058
Schistosoma mansoni	patched 1	0.002	0.0124	0.02
Schistosoma mansoni	integrin beta subunit	0.0316	0.6171	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0214	0.0214
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0024	0.0215	0.0215
Giardia lamblia	Tenascin precursor	0.0017	0.0076	0.5
Schistosoma mansoni	membrane associated proteins in eicosanoid and glutathione metabolism family member	0.0194	0.3694	0.5986
Loa Loa (eye worm)	hypothetical protein	0.002	0.0124	0.0124
Loa Loa (eye worm)	calcium channel	0.0059	0.093	0.093
Schistosoma mansoni	hypothetical protein	0.0019	0.0109	0.0177
Echinococcus granulosus	lysine specific demethylase 5A	0.0016	0.0058	0.0074
Wolbachia endosymbiont of Brugia malayi	Na+/H+-dicarboxylate symporter	0.0209	0.3986	0.5
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0017	0.0064	0.0082
Onchocerca volvulus	Excitatory amino acid transporter homolog	0.0209	0.3986	1
Brugia malayi	Kelch motif family protein	0.0081	0.1387	0.1387
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.0059	0.093	0.1187
Echinococcus granulosus	excitatory amino acid transporter 3	0.0209	0.3986	0.5088
Echinococcus granulosus	Protein patched homolog 1	0.002	0.0124	0.0158
Echinococcus multilocularis	sodium:dicarboxylate symporter	0.0092	0.1613	0.2059
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.0048	0.0706	0.09
Schistosoma mansoni	sodium/dicarboxylate symporter-related	0.0092	0.1613	0.2614
Echinococcus granulosus	gamma secretase subunit aph 1	0.0184	0.3489	0.4453
Plasmodium falciparum	transporter, putative	0.0014	0	0.5
Echinococcus multilocularis	lysine specific demethylase 5A	0.0016	0.0058	0.0074
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.002	0.0124	0.0124
Echinococcus granulosus	sodium:dicarboxylate symporter	0.0209	0.3986	0.5088
Echinococcus multilocularis	Excitatory amino acid transporter	0.0209	0.3986	0.5088
Schistosoma mansoni	solute carrier family 1 (glial high affinity glutamate transporter	0.0209	0.3986	0.6459
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0048	0.0706	0.1143
Brugia malayi	hypothetical protein	0.0017	0.0064	0.0064
Echinococcus multilocularis	jumonji domain containing protein	0.0019	0.0108	0.0138
Echinococcus multilocularis	geminin	0.0079	0.1328	0.1696
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Giardia lamblia	Tenascin-X	0.0017	0.0076	0.5
Echinococcus granulosus	neutral amino acid transporter	0.0209	0.3986	0.5088
Echinococcus granulosus	Niemann Pick C1 protein	0.0046	0.0656	0.0837
Loa Loa (eye worm)	voltage-dependent calcium channel	0.0021	0.0144	0.0144
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0044	0.0628	0.0801
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0059	0.093	0.093
Echinococcus multilocularis	protein jagged 2	0.0017	0.0076	0.0098
Toxoplasma gondii	transporter, cation channel family protein	0.0021	0.0144	0.2269
Echinococcus multilocularis	sodium:dicarboxylate symporter	0.0209	0.3986	0.5088
Loa Loa (eye worm)	serotonin transporter b	0.005	0.0736	0.0736
Schistosoma mansoni	integrin alpha-ps	0.0031	0.0355	0.0575
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0023	0.0196	0.0196
Schistosoma mansoni	aldehyde dehydrogenase	0.003	0.0345	0.0559
Echinococcus multilocularis	excitatory amino acid transporter 3	0.0209	0.3986	0.5088
Trichomonas vaginalis	hypothetical protein	0.0083	0.1427	1
Echinococcus granulosus	voltage dependent calcium channel	0.0059	0.093	0.1187
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0076	0.0076
Loa Loa (eye worm)	MH2 domain-containing protein	0.0055	0.0854	0.0854
Chlamydia trachomatis	glutamate symporter	0.0209	0.3986	1
Echinococcus granulosus	microsomal glutathione S transferase 3	0.0045	0.0634	0.0809
Echinococcus granulosus	fibrillin 2	0.0017	0.0076	0.0098
Brugia malayi	Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog	0.0059	0.093	0.093
Schistosoma mansoni	microsomal glutathione s-transferase	0.0045	0.0634	0.1027
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel\|voltage dependent L type calcium channel subu	0.0059	0.093	0.1187
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel alpha 1	0.0059	0.093	0.1187
Loa Loa (eye worm)	integrin beta-2	0.0503	1	1
Loa Loa (eye worm)	gamma-secretase subunit aph-1	0.0184	0.3489	0.3489
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Brugia malayi	EGF-like domain containing protein	0.0017	0.0076	0.0076
Echinococcus multilocularis	protein dispatched 1	0.0022	0.018	0.023
Trypanosoma brucei	Aph-1 protein, putative	0.0072	0.1191	1
Toxoplasma gondii	hypothetical protein	0.0017	0.0076	0.1207
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0016	0.0058	0.0094
Trichomonas vaginalis	conserved hypothetical protein	0.0083	0.1427	1
Echinococcus granulosus	Excitatory amino acid transporter	0.0209	0.3986	0.5088
Schistosoma mansoni	transcription factor LCR-F1	0.0017	0.0064	0.0104
Plasmodium vivax	amine transporter, putative	0.0014	0	0.5
Schistosoma mansoni	hypothetical protein	0.0017	0.0064	0.0104
Schistosoma mansoni	aldehyde dehydrogenase	0.003	0.0345	0.0559
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0023	0.0196	0.0196
Loa Loa (eye worm)	hypothetical protein	0.005	0.0736	0.0736

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3497123

Bibliographic References

No literature references available for this target.

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Detailed information for compound 2071555