Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | adenine aminohydrolase | 0.0284 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0284 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0284 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0284 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0284 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0284 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0284 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0284 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0284 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0284 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0284 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0284 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0284 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0284 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0284 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0284 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0284 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0284 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.