Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0491 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0491 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0491 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0491 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0491 | 1 | 1 |
Leishmania major | adenine aminohydrolase | 0.0491 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0491 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0491 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0491 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0491 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0491 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0491 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0491 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0491 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.