Detailed information for compound 2073060

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.25 | Formula: C14H14IN3OS
  • H donors: 2 H acceptors: 2 LogP: 4.07 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1csc(n1)NCC(=O)c1c[nH]c2c1cccc2.I
  • InChi: 1S/C14H13N3OS.HI/c1-9-8-19-14(17-9)16-7-13(18)11-6-15-12-5-3-2-4-10(11)12;/h2-6,8,15H,7H2,1H3,(H,16,17);1H
  • InChiKey: KIJUCBAIWGHDEG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.0023 0.0154 0.0122
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0012 0.006 0.0494
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0598 0.0568
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0046 0.0014
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.114 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0012 0.006 0.0028
Leishmania major serine-threonine dehydratase, putative 0.0055 0.0439 0.7182
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0598 0.0598
Loa Loa (eye worm) hypothetical protein 0.0052 0.0412 0.0397
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0119 0.0087
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0154 0.0139
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0154 0.2982
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0012 0.006 0.0028
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0012 0.006 0.0494
Echinococcus multilocularis neutral amino acid transporter A 0.114 1 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0119 0.2135
Echinococcus multilocularis excitatory amino acid transporter 2 0.114 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0578 0.0578
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0119 0.1991
Echinococcus granulosus excitatory amino acid transporter 2 0.114 1 1
Giardia lamblia Threonine dehydratase lateral transfer candidate 0.0055 0.0439 1
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0119 0.0087
Mycobacterium leprae Conserved hypothetical protein 0.0012 0.006 0.0688
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0308 0.6773
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0012 0.006 0.0494
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0201 0.2981
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0046 0.0014
Echinococcus multilocularis 0.0012 0.006 0.0028
Mycobacterium tuberculosis Probable threonine dehydratase IlvA 0.0055 0.0439 0.0408
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0012 0.006 0.0494
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0012 0.006 0.0494
Echinococcus granulosus bloom syndrome protein 0.0026 0.0179 0.0147
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0012 0.006 0.0494
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.0578 0.0548
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0119 0.0087
Toxoplasma gondii succinyl-CoA-synthetase alpha SCSA 0.0009 0.0032 0.054
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0074 0.1544
Trypanosoma cruzi serine-threonine dehydratase, putative 0.0055 0.0439 1
Loa Loa (eye worm) cytochrome P450 0.0012 0.006 0.0046
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0119 0.0104
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.8583 0.8578
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0012 0.006 0.0028
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0012 0.006 0.0494
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0578 0.0564
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0012 0.006 0.0028
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0837 0.0807
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0119 0.0104
Leishmania major cytochrome p450-like protein 0.0012 0.006 0.0494
Mycobacterium ulcerans threonine dehydratase 0.0055 0.0439 0.7182
Echinococcus granulosus Excitatory amino acid transporter 0.114 1 1
Leishmania major cytochrome p450-like protein 0.0023 0.0154 0.2141
Loa Loa (eye worm) hypothetical protein 0.0021 0.0133 0.0119
Plasmodium vivax JmjC domain containing protein 0.0019 0.0119 0.5144
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0598 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0012 0.006 0.0028
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0012 0.006 0.0494
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.006 0.0494
Loa Loa (eye worm) hypothetical protein 0.0011 0.0045 0.0031
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0119 0.2135
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0012 0.006 0.0688
Leishmania major cytochrome p450-like protein 0.0012 0.006 0.0494
Echinococcus granulosus excitatory amino acid transporter 2 0.114 1 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0308 0.0293
Loa Loa (eye worm) hypothetical protein 0.0019 0.0119 0.0104
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0119 0.0104
Brugia malayi cytochrome P450 0.0012 0.006 0.0028
Echinococcus multilocularis Excitatory amino acid transporter 0.114 1 1
Brugia malayi jmjC domain containing protein 0.0071 0.0578 0.0548
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0119 0.0087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0598 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0012 0.006 0.0494
Schistosoma mansoni DNA helicase recq1 0.0011 0.0046 0.0046
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0012 0.006 0.0028
Toxoplasma gondii ATP-citrate lyase, putative 0.0046 0.0361 0.6037
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0598 0.0568
Echinococcus granulosus sodium:dicarboxylate symporter 0.114 1 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0837 0.0807
Onchocerca volvulus Serine racemase homolog 0.0055 0.0439 0.0408
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0028 0.0201 0.2981
Schistosoma mansoni rotamase 0.004 0.0308 0.0308
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0012 0.006 0.0494
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.006 0.0688
Onchocerca volvulus Excitatory amino acid transporter homolog 0.114 1 1
Echinococcus granulosus cytochrome P450 2K1 0.0012 0.006 0.0028
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0012 0.006 0.0028
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0119 0.0087
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0201 0.0169
Chlamydia trachomatis neutral amino acid transporter 0.0505 0.4406 0.4388
Trichomonas vaginalis rotamase, putative 0.0039 0.0299 0.6567
Brugia malayi Cytochrome P450 family protein 0.0023 0.0154 0.0122
Echinococcus multilocularis neutral amino acid transporter A 0.114 1 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0299 0.682
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0299 0.6567
Entamoeba histolytica threonine dehydratase, putative 0.0055 0.0439 1
Schistosoma mansoni DNA helicase recq5 0.0011 0.0046 0.0046
Toxoplasma gondii cytochrome p450 superfamily protein 0.0012 0.006 0.1008
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0046 0.0014
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0299 0.4716
Brugia malayi Bloom's syndrome protein homolog 0.0026 0.0179 0.0147
Echinococcus granulosus Excitatory amino acid transporter 0.114 1 1
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0119 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0012 0.006 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0012 0.006 0.0028
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0119 0.0119
Schistosoma mansoni cytochrome P450 0.0012 0.006 0.006
Trichomonas vaginalis DNA helicase recq1, putative 0.0026 0.0179 0.3615
Brugia malayi jmjC domain containing protein 0.0019 0.0119 0.0087
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0201 0.336
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0299 0.6567
Loa Loa (eye worm) succinate-CoA ligase 0.0009 0.0032 0.0018
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0154 0.2141
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0012 0.006 0.0028
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0119 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0012 0.006 0.0028
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0201 0.2981
Brugia malayi jmjC domain containing protein 0.0071 0.0578 0.0548
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0154 0.2982
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0012 0.006 0.0494
Loa Loa (eye worm) RecQ helicase 0.0026 0.0179 0.0165
Treponema pallidum glutamate/aspartate transporter 0.0505 0.4406 1
Echinococcus multilocularis expressed protein 0.004 0.0308 0.0276
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0119 0.1991
Brugia malayi Cytochrome P450 family protein 0.0012 0.006 0.0028
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0011 0.0046 0.0808
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0578 0.0548
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0012 0.006 0.0028
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0299 0.5002
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0074 0.1676
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0046 0.0014
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0598 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0201 0.336
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0837 0.0807
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0837 0.0837
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.006 0.1008
Brugia malayi jmjC domain containing protein 0.0019 0.0119 0.0087
Echinococcus granulosus excitatory amino acid transporter 3 0.114 1 1
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0012 0.006 0.0494
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0505 0.4406 0.4406
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.006 0.0688
Echinococcus granulosus phd:f box containing protein 0.0019 0.0119 0.0087
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0106 0.4352
Schistosoma mansoni hypothetical protein 0.0012 0.006 0.006
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.006 0.1048
Echinococcus granulosus expressed protein 0.004 0.0308 0.0276
Chlamydia trachomatis glutamate symporter 0.114 1 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0505 0.4406 0.4406
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0012 0.006 0.0028
Loa Loa (eye worm) ATP-citrate synthase 0.0046 0.0361 0.0347
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.0578 0.0548
Echinococcus multilocularis excitatory amino acid transporter 3 0.114 1 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0046 0.0014
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.114 1 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0012 0.006 0.0494
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.0055 0.0439 1
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0308 0.0276
Schistosoma mansoni ATP-citrate synthase 0.0039 0.0299 0.0299
Entamoeba histolytica threonine dehydratase, putative 0.0055 0.0439 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0119 0.0104
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.0055 0.0439 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0012 0.006 0.0494
Loa Loa (eye worm) hypothetical protein 0.01 0.0837 0.0824
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0598 0.0568
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0119 0.0087
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0074 0.1014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0012 0.006 0.0028
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0012 0.006 0.0494
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0201 0.6321
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0119 0.0087
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0074 0.1014
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0201 1
Schistosoma mansoni threonine dehydratase/deaminase 0.0055 0.0439 0.0439
Brugia malayi jmjC domain containing protein 0.0019 0.0119 0.0087
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0299 1
Trichomonas vaginalis DNA helicase recq, putative 0.0026 0.0179 0.3615
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0132 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0012 0.006 0.0028
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.114 1 1
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0201 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0074 0.0728
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0012 0.006 0.0494
Echinococcus granulosus neutral amino acid transporter A 0.114 1 1
Mycobacterium leprae Probable threonine dehydratase IlvA 0.0055 0.0439 1
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.114 1 1
Echinococcus multilocularis excitatory amino acid transporter 2 0.114 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0104 0.1737
Leishmania major hypothetical protein, conserved 0.0019 0.0119 0.1533
Schistosoma mansoni jumonji domain containing protein 0.0071 0.0578 0.0578
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0012 0.006 0.0494
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0028 0.0201 0.0169
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0154 0.0139
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0578 0.0578
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0012 0.006 0.0028
Brugia malayi Cytochrome P450 family protein 0.0041 0.0313 0.0282
Echinococcus multilocularis Excitatory amino acid transporter 0.114 1 1
Entamoeba histolytica threonine dehydratase, putative 0.0055 0.0439 1
Trypanosoma cruzi serine-threonine dehydratase, putative 0.0055 0.0439 1
Onchocerca volvulus 0.01 0.0837 0.0807
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0012 0.006 0.0494
Trichomonas vaginalis threonine dehydratase/deaminase, putative 0.0055 0.0439 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.006 0.0688
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0598 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0119 0.3251
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0598 0.0598
Echinococcus granulosus neutral amino acid transporter 0.114 1 1
Mycobacterium leprae putative cytochrome p450 0.0012 0.006 0.0688
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0012 0.006 0.0494
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0012 0.006 0.0028
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0046 0.0014
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0119 0.0119
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0119 0.0119
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0028 0.0201 0.0169
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0012 0.006 0.0028
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0598 1
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0505 0.4406 0.4388
Brugia malayi ATP-citrate synthase 0.0046 0.0361 0.033
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0012 0.006 0.0028
Trichomonas vaginalis rotamase, putative 0.004 0.0308 0.6773
Schistosoma mansoni succinyl-CoA synthetase-related 0.0009 0.0032 0.0032
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0505 0.4406 0.4388
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0154 0.0139
Brugia malayi Pyridoxal-phosphate dependent enzyme family protein 0.0055 0.0439 0.0408
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0578 0.0548
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0012 0.006 0.0028
Loa Loa (eye worm) excitatory amino acid transporter 0.114 1 1
Echinococcus multilocularis bloom syndrome protein 0.0026 0.0179 0.0147
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0119 0.0087
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0012 0.006 0.0494
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0119 0.5144
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0012 0.006 0.1048
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0313 0.0299
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0154 0.454
Entamoeba histolytica hypothetical protein 0.0028 0.0201 0.4582
Echinococcus multilocularis neutral amino acid transporter A 0.114 1 1
Brugia malayi jmjC domain containing protein 0.0019 0.0119 0.0087
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0119 0.0087
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0152 0.7076
Loa Loa (eye worm) hypothetical protein 0.0019 0.0119 0.0104
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0012 0.006 0.0494
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0046 0.0768
Echinococcus granulosus neutral amino acid transporter A 0.114 1 1
Treponema pallidum glutamate transporter 0.0505 0.4406 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0046 0.0768
Echinococcus multilocularis sodium:dicarboxylate symporter 0.114 1 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0046 0.0031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0012 0.006 0.0688
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0201 0.4151
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0012 0.006 0.0028

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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