Detailed information for compound 2073149

Basic information

Technical information
  • TDR Targets ID: 2073149
  • Name: (1S,2R)-1-phenyl-2-[[(1S)-1-phenylpropyl]amin o]propan-1-ol
  • MW: 269.381 | Formula: C18H23NO
  • H donors: 2 H acceptors: 1 LogP: 3.5 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H](c1ccccc1)N[C@@H]([C@H](c1ccccc1)O)C
  • InChi: 1S/C18H23NO/c1-3-17(15-10-6-4-7-11-15)19-14(2)18(20)16-12-8-5-9-13-16/h4-14,17-20H,3H2,1-2H3/t14-,17+,18-/m1/s1
  • InChiKey: UPWWPDXPFCAURY-FHLIZLRMSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0088 0.0191 0.0122
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0606 0.2013 0.1957
Trypanosoma brucei transcription elongation factor s-II, putative 0.0176 0.05 0.1436
Echinococcus granulosus peptide allatostatin:somatostatin 0.0216 0.0641 0.0619
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0176 0.05 0.1436
Echinococcus multilocularis hepatoma derived growth factor protein 0.0176 0.05 0.0434
Schistosoma mansoni amine GPCR 0.0216 0.0641 0.0632
Echinococcus granulosus histone h3 methyltransferase 0.2879 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Echinococcus granulosus 7tm_1 domain containing protein 0.0216 0.0641 0.0619
Echinococcus multilocularis fmrfamide receptor 0.0216 0.0641 0.0576
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0143 0.0386 0.0787
Brugia malayi putative neuropeptide receptor 0.0216 0.0641 0.0632
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0053 0.007 0.006
Trichomonas vaginalis poly(p)/ATP NAD kinase, putative 0.0347 0.1102 0.2248
Loa Loa (eye worm) hypothetical protein 0.0629 0.2093 0.2084
Trypanosoma cruzi spermidine synthase, putative 0.0741 0.2486 0.7192
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus disco interacting protein 2 0.0629 0.2093 0.2074
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0104 0.0249 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Echinococcus multilocularis uridine phosphorylase 1 0.0188 0.0544 0.0477
Toxoplasma gondii histone lysine methyltransferase SET1 0.0101 0.0237 0.047
Echinococcus granulosus g protein coupled receptor 0.0216 0.0641 0.0619
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Schistosoma mansoni bromo adjacent homology domain containing 0.0073 0.0137 0.0128
Echinococcus multilocularis cpg binding protein 0.0593 0.1967 0.1911
Brugia malayi jmjC domain containing protein 0.0075 0.0146 0.0136
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0188 0.0544 0.1562
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0046 0.0044 0.0103
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0019 0.0008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1281 0.4383 0.4377
Echinococcus granulosus neuropeptide Y receptor 0.0216 0.0641 0.0619
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0698 0.2336 0.2282
Brugia malayi NNMT/PNMT/TEMT family protein 0.1512 0.5197 0.5192
Echinococcus granulosus G protein coupled receptor 139 0.0216 0.0641 0.0619
Schistosoma mansoni adenosylhomocysteinase 0.0853 0.2879 0.2872
Onchocerca volvulus 0.0176 0.05 0.1005
Echinococcus multilocularis methylthioadenosine phosphorylase 0.1016 0.3454 0.3408
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0188 0.0544 0.3535
Loa Loa (eye worm) hypothetical protein 0.0039 0.002 0.001
Schistosoma mansoni hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0698 0.2336 0.6758
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Toxoplasma gondii hypothetical protein 0.1382 0.4738 1
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.006 0.0093 0.0255
Onchocerca volvulus 0.0216 0.0641 0.1295
Brugia malayi Nucleoside transporter family protein 0.0104 0.0249 0.0239
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.2879 1 1
Echinococcus granulosus somatostatin receptor 0.0216 0.0641 0.0619
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0365 0.1167 0.3368
Echinococcus granulosus histone lysine methyltransferase setb 0.0214 0.0634 0.0612
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0216 0.0641 0.1295
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus hypothetical protein 0.0216 0.0641 0.0619
Trypanosoma cruzi arginine N-methyltransferase, type I 0.004 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0253 0.0772 0.1563
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0216 0.0641 0.0576
Onchocerca volvulus 0.0216 0.0641 0.1295
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0042 0.0029 0.004
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0083 0.0172 0.0539
Onchocerca volvulus 0.0216 0.0641 0.1295
Schistosoma mansoni biogenic amine receptor 0.0216 0.0641 0.0632
Toxoplasma gondii hypothetical protein 0.0365 0.1167 0.2439
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0083 0.0172 0.0334
Schistosoma mansoni adenosylhomocysteinase 0.0528 0.1737 0.1729
Echinococcus multilocularis DNA methyltransferase 2, putative 0.087 0.294 0.289
Toxoplasma gondii phosphorylase family protein 0.0188 0.0544 0.112
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1783
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0216 0.0641 0.0576
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0075 0.0146 0.0077
Echinococcus granulosus metastasis associated protein MTA1 0.0073 0.0137 0.0114
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0268 0.0823 0.1677
Schistosoma mansoni hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni neuropeptide receptor 0.0216 0.0641 0.0632
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0698 0.2336 0.2328
Leishmania major hypothetical protein, conserved 0.0365 0.1167 0.3368
Brugia malayi S-adenosylmethionine synthetase 0.0101 0.0238 0.0228
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0188 0.0544 0.1521
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0365 0.1167 0.3368
Trichomonas vaginalis CDC6, putative 0.0073 0.0137 0.0271
Onchocerca volvulus 0.0114 0.0282 0.0557
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.087 0.294 1
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Echinococcus granulosus neuropeptides capa receptor 0.0216 0.0641 0.0619
Echinococcus multilocularis neuropeptide receptor 0.0216 0.0641 0.0576
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus neuropeptide s receptor 0.0216 0.0641 0.0619
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Schistosoma mansoni purine nucleoside phosphorylase 0.0188 0.0544 0.0534
Onchocerca volvulus 0.0216 0.0641 0.1295
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1016 0.3454 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis S adenosylmethionine synthase type 1 0.0101 0.0238 0.017
Schistosoma mansoni neuropeptide F-like receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis g protein coupled receptor 0.0216 0.0641 0.0576
Echinococcus granulosus biogenic amine 5HT receptor 0.0216 0.0641 0.0619
Schistosoma mansoni protein arginine n-methyltransferase 0.0109 0.0265 0.0256
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0143 0.0386 0.0319
Leishmania major S-adenosylmethionine decarboxylase 0.0698 0.2336 0.6758
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0086 0.0185 0.0116
Brugia malayi Disco-interacting protein 2 homolog 0.0629 0.2093 0.2084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Entamoeba histolytica nucleoside transporter, putative 0.0104 0.0249 0.0772
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0853 0.2879 0.6065
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0365 0.1167 0.3368
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0216 0.0641 0.0576
Schistosoma mansoni uridine phosphorylase 0.0188 0.0544 0.0534
Schistosoma mansoni neuropeptide F-like receptor 0.0216 0.0641 0.0632
Plasmodium vivax protein arginine N-methyltransferase 5, putative 0.0055 0.0074 0.0202
Leishmania major methylthioadenosine phosphorylase, putative 0.1016 0.3454 1
Brugia malayi ELM2 domain containing protein 0.0073 0.0137 0.0127
Toxoplasma gondii histone arginine methyltransferase PRMT5 0.0055 0.0074 0.0125
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0216 0.0641 0.0576
Echinococcus multilocularis peregrin 0.0199 0.0581 0.0515
Brugia malayi SET domain containing protein 0.0606 0.2013 0.2005
Loa Loa (eye worm) uridine phosphorylase 0.0188 0.0544 0.0534
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi G-protein coupled receptor 0.0216 0.0641 0.0632
Brugia malayi SET domain containing protein 0.0182 0.0522 0.0513
Loa Loa (eye worm) CXXC zinc finger family protein 0.0591 0.1959 0.195
Mycobacterium ulcerans 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.1027 0.3493 1
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Toxoplasma gondii IMP dehydrogenas 0.0088 0.0191 0.0373
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0075 0.0146 0.0123
Loa Loa (eye worm) hypothetical protein 0.0253 0.0772 0.0763
Echinococcus multilocularis somatostatin receptor 0.0216 0.0641 0.0576
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0073 0.0137 0.0128
Plasmodium falciparum adenosylhomocysteinase 0.0853 0.2879 0.6065
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0216 0.0641 0.0632
Echinococcus granulosus fmrfamide receptor 0.0216 0.0641 0.0619
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0088 0.0191 0.0181
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0088 0.0191 0.0506
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0188 0.0544 0.0534
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1512 0.5197 0.5192
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis disco interacting protein 2 0.0629 0.2093 0.2037
Echinococcus granulosus biogenic amine 5HT receptor 0.0216 0.0641 0.0619
Trypanosoma cruzi GMP reductase 0.0088 0.0191 0.0539
Echinococcus multilocularis serotonin receptor 0.0216 0.0641 0.0576
Schistosoma mansoni cpg binding protein 0.0593 0.1967 0.1959
Schistosoma mansoni phd finger protein 0.0176 0.05 0.0491
Toxoplasma gondii hypothetical protein 0.0176 0.05 0.1028
Echinococcus multilocularis dro:myosuppressin receptor 0.0216 0.0641 0.0576
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0195 0.0567 0.0501
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi Dopamine receptor protein 2 0.0216 0.0641 0.0632
Loa Loa (eye worm) spermidine synthase 0.0741 0.2486 0.2478
Leishmania major hypothetical protein, conserved 0.0176 0.05 0.1436
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0216 0.0641 0.0632
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0111 0.0271 0.0262
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0071 0.0133 0.037
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0698 0.2336 0.2318
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0161 0.0449 0.0919
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Onchocerca volvulus 0.0216 0.0641 0.1295
Plasmodium falciparum S-adenosylmethionine synthetase 0.0101 0.0238 0.0474
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0088 0.0191 0.0539
Schistosoma mansoni poly(p)/ATP NAD kinase 0.0347 0.1102 0.1093
Loa Loa (eye worm) hypothetical protein 0.0094 0.0211 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0214 0.0634 0.0625
Brugia malayi Tachykinin-like peptides receptor 99D 0.0216 0.0641 0.0632
Brugia malayi uridine phosphorylase family protein 0.0188 0.0544 0.0534
Schistosoma mansoni uridine phosphorylase 0.0188 0.0544 0.0534
Echinococcus multilocularis neuropeptides capa receptor 0.0216 0.0641 0.0576
Onchocerca volvulus 0.0216 0.0641 0.1295
Trypanosoma brucei GMP reductase 0.0088 0.0191 0.0539
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus microtubule associated protein 2 0.0614 0.204 0.2022
Onchocerca volvulus 0.0216 0.0641 0.1295
Onchocerca volvulus 0.0629 0.2093 0.4273
Echinococcus granulosus protein arginine N methyltransferase 5 0.0055 0.0074 0.005
Echinococcus granulosus cpg binding protein 0.0593 0.1967 0.1948
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi ORL1-like opioid receptor 0.0216 0.0641 0.0632
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0853 0.2879 0.5892
Echinococcus multilocularis spermidine synthase 0.0741 0.2486 0.2433
Echinococcus multilocularis PWWP domain containing protein 2A 0.0176 0.05 0.0434
Loa Loa (eye worm) hypothetical protein 0.0073 0.0137 0.0127
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0585 0.1937 0.671
Brugia malayi hypothetical protein 0.0094 0.0211 0.0201
Entamoeba histolytica hypothetical protein 0.0188 0.0544 0.1783
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0088 0.0191 0.0539
Onchocerca volvulus 0.0216 0.0641 0.1295
Trypanosoma cruzi spermidine synthase, putative 0.0741 0.2486 0.7192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Schistosoma mansoni S-adenosylmethionine synthetase 0.0101 0.0238 0.0229
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0853 0.2879 0.8332
Loa Loa (eye worm) hypothetical protein 0.0075 0.0146 0.0136
Mycobacterium leprae Probable2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin 0.1027 0.3493 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0216 0.0641 0.0619
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0038 0.0015 0.0617
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Loa Loa (eye worm) hypothetical protein 0.0073 0.0137 0.0127
Echinococcus granulosus g protein coupled receptor 0.0216 0.0641 0.0619
Schistosoma mansoni suppressor of variegation 4-20-related 0.0128 0.0332 0.0322
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.1016 0.3454 0.3448
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.1382 0.4738 1
Echinococcus granulosus neuropeptides capa receptor 0.0216 0.0641 0.0619
Brugia malayi Melatonin receptor type 1A 0.0216 0.0641 0.0632
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Loa Loa (eye worm) hypothetical protein 0.0104 0.0249 0.0239
Brugia malayi AKH receptor 0.0216 0.0641 0.0632
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0149 0.0407 0.1165
Echinococcus multilocularis neuropeptide receptor 0.0216 0.0641 0.0576
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.007 0.0133
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0104 0.0249 0.05
Schistosoma mansoni amine GPCR 0.0216 0.0641 0.0632
Loa Loa (eye worm) Skb1 methyltransferase 0.0055 0.0074 0.0063
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis orexin receptor type 2 0.0216 0.0641 0.0576
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0214 0.0634 0.0625
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0629 0.2093 0.2085
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0073 0.0137 0.0128
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0081 0.0168 0.0325
Onchocerca volvulus 0.0216 0.0641 0.1295
Brugia malayi neuropeptide F receptor 0.0216 0.0641 0.0632
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0071 0.0133 0.037
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.05 0.1436
Schistosoma mansoni hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.087 0.294 0.8508
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0053 0.007 0.006
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0104 0.0249 0.0226
Trypanosoma brucei histone-lysine n-methyltransferase 0.0365 0.1167 0.3368
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0216 0.0641 0.0632
Schistosoma mansoni biogenic amine (5HT) receptor 0.0216 0.0641 0.0632
Brugia malayi hypothetical protein 0.0176 0.05 0.049
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1783
Leishmania major guanosine monophosphate reductase 0.0088 0.0191 0.0539
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0216 0.0641 0.0576
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0853 0.2879 0.8332
Echinococcus granulosus 7TM GPCR rhodopsin 0.0216 0.0641 0.0619
Onchocerca volvulus 0.0216 0.0641 0.1295
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0216 0.0641 0.0632
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Plasmodium vivax S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0765
Echinococcus multilocularis G-protein coupled receptor, putative 0.0216 0.0641 0.0576
Echinococcus multilocularis arginine glutamic acid dipeptide (RE) repeats 0.0073 0.0137 0.0068
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0128 0.0332 0.0309
Brugia malayi Spermidine synthase 0.0741 0.2486 0.2478
Loa Loa (eye worm) hypothetical protein 0.0163 0.0456 0.0446
Echinococcus granulosus tm gpcr rhodopsin 0.0216 0.0641 0.0619
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0365 0.1167 0.3368
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0216 0.0641 0.0576
Schistosoma mansoni purine nucleoside phosphorylase 0.0188 0.0544 0.0534
Onchocerca volvulus Neuropeptide F receptor homolog 0.0216 0.0641 0.1295
Echinococcus granulosus protein arginine N methyltransferase 8 0.0053 0.007 0.0046
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0698 0.2336 0.6758
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0161 0.0449 0.0382
Schistosoma mansoni microtubule-associated protein tau 0.0614 0.204 0.2033
Entamoeba histolytica hypothetical protein 0.0176 0.05 0.1635
Plasmodium falciparum spermidine synthase 0.0741 0.2486 0.5232
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0195 0.0567 0.0544
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0216 0.0641 0.0576
Toxoplasma gondii orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase 0.006 0.0093 0.0165
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.1016 0.3454 0.989
Entamoeba histolytica Skb1 methyltransferase, putative 0.0055 0.0074 0.0172
Mycobacterium ulcerans inorganic polyphosphate/ATP-NAD kinase 0.0347 0.1102 0.3125
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0149 0.0407 0.1165
Echinococcus granulosus allatostatin A receptor 0.0216 0.0641 0.0619
Loa Loa (eye worm) hypothetical protein 0.0214 0.0634 0.0624
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0149 0.0407 0.1165
Echinococcus granulosus protein arginine methyltransferase 0.0053 0.007 0.0046
Schistosoma mansoni hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus uridine 5' monophosphate synthase 0.0071 0.0133 0.0109
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Giardia lamblia Hypothetical protein 0.0104 0.0249 0.0119
Brugia malayi G protein-coupled receptor 0.0216 0.0641 0.0632
Trypanosoma cruzi arginine N-methyltransferase, type I 0.004 0.0024 0.0054
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0104 0.0249 0.05
Echinococcus granulosus protein arginine N methyltransferase 7 0.0149 0.0407 0.0384
Echinococcus granulosus methylthioadenosine phosphorylase 0.1016 0.3454 0.3439
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0216 0.0641 0.0632
Schistosoma mansoni hypothetical protein 0.0073 0.0137 0.0128
Schistosoma mansoni neuropeptide receptor 0.0216 0.0641 0.0632
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0698 0.2336 0.2328
Echinococcus granulosus adenosylhomocysteinase 0.0853 0.2879 0.2862
Brugia malayi G-protein coupled receptor 0.0216 0.0641 0.0632
Plasmodium vivax spermidine synthase, putative 0.0741 0.2486 0.8447
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Echinococcus granulosus arginine glutamic acid dipeptide RE repeats 0.0073 0.0137 0.0114
Echinococcus multilocularis histone h3 methyltransferase 0.2879 1 1
Loa Loa (eye worm) SET domain-containing protein 0.0606 0.2013 0.2005
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Giardia lamblia UPL-1 0.0188 0.0544 0.3535
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1783
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Brugia malayi Protein arginine N-methyltransferase 0.0149 0.0407 0.0397
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0216 0.0641 0.0632
Loa Loa (eye worm) Carm1-pending protein 0.0143 0.0386 0.0376
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Schistosoma mansoni hypothetical protein 0.004 0.0024 0.0014
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0073 0.0137 0.0128
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0853 0.2879 0.9793
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0216 0.0641 0.0632
Echinococcus granulosus NAD kinase 0.0347 0.1102 0.1081
Plasmodium vivax SET domain protein, putative 0.0161 0.0449 0.1484
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0698 0.2336 0.6758
Schistosoma mansoni hepatoma derived growth factor 0.0176 0.05 0.0491
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0188 0.0544 0.1562
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0053 0.007 0.0116
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0365 0.1167 0.3368
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Echinococcus granulosus SET and MYND domain containing protein 3 0.0063 0.0102 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.0614 0.204 0.1985
Treponema pallidum hypothetical protein 0.0347 0.1102 1
Trypanosoma cruzi GMP reductase 0.0088 0.0191 0.0539
Echinococcus multilocularis serotonin receptor 0.0216 0.0641 0.0576
Mycobacterium ulcerans spermidine synthase 0.0585 0.1937 0.5527
Mycobacterium ulcerans S-adenosylmethionine synthetase 0.0101 0.0238 0.0643
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Echinococcus multilocularis neuropeptide s receptor 0.0216 0.0641 0.0576
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.004 0.0024 0.0038
Brugia malayi GATA zinc finger family protein 0.0073 0.0137 0.0127
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1808
Echinococcus multilocularis fmrfamide receptor 0.0216 0.0641 0.0576
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus tm gpcr rhodopsin 0.0216 0.0641 0.0619
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0073 0.0137 0.0068
Echinococcus granulosus neuropeptide FF receptor 2 0.0216 0.0641 0.0619
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Echinococcus granulosus peregrin 0.0199 0.0581 0.0559
Onchocerca volvulus 0.1423 0.4883 1
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0104 0.0249 0.0489
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Leishmania major spermidine synthase 0.0741 0.2486 0.7192
Brugia malayi GnHR receptor homolog 0.0216 0.0641 0.0632
Brugia malayi G protein-coupled receptor F59B2.13 0.0216 0.0641 0.0632
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0188 0.0544 0.1783
Brugia malayi Skb1 methyltransferase family protein 0.0055 0.0074 0.0063
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0188 0.0544 0.1521
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.004 0.0024 0.0038
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0216 0.0641 0.0619
Trypanosoma brucei spermidine synthase 0.0741 0.2486 0.7192
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0216 0.0641 0.0632
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0324 0.1022 0.1014
Echinococcus granulosus neuropeptide receptor A26 0.0216 0.0641 0.0619
Echinococcus granulosus tachykinin peptides receptor 99D 0.0216 0.0641 0.0619
Echinococcus granulosus sex peptide receptor 0.0216 0.0641 0.0619
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Leishmania major modification methylase-like protein 0.087 0.294 0.8508
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.034 0.1077 0.225
Giardia lamblia Inorganic polyphosphate/ATP-NAD kinase, putative 0.0347 0.1102 1
Echinococcus multilocularis bromo adjacent y domain containing 1 0.0073 0.0137 0.0068
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.087 0.294 0.6193
Echinococcus granulosus DNA methyltransferase 2, putative 0.087 0.294 0.2923
Trichomonas vaginalis poly(p)/ATP NAD kinase, putative 0.0347 0.1102 0.2248
Leishmania major hypothetical protein, conserved 0.0365 0.1167 0.3368
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0216 0.0641 0.1295
Schistosoma mansoni neuropeptide receptor 0.0216 0.0641 0.0632
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0698 0.2336 0.6758
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni neuropeptide f receptor 76f 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0365 0.1167 0.3368
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0606 0.2013 0.1994
Schistosoma mansoni biogenic amine receptor 0.0216 0.0641 0.0632
Treponema pallidum pfs protein (pfs) 0.0188 0.0544 0.3535
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0088 0.0191 0.7996
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0188 0.0544 0.1521
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni alpha-1 adrenergic receptor 0.0216 0.0641 0.0632
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0216 0.0641 0.0576
Brugia malayi neuropeptide F receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis neuropeptides capa receptor 0.0216 0.0641 0.0576
Brugia malayi hypothetical protein 0.0253 0.0772 0.0763
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0216 0.0641 0.0576
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.0544 0.1104
Brugia malayi RE15519p 0.0216 0.0641 0.0632
Leishmania major arginine N-methyltransferase, type I 0.004 0.0024 0.0054
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0216 0.0641 0.0619
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.087 0.294 0.6193
Loa Loa (eye worm) methionine adenosyltransferase 0.0101 0.0238 0.0228
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0088 0.0191 0.0539
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Loa Loa (eye worm) hypothetical protein 0.0104 0.0249 0.0239
Schistosoma mansoni amine GPCR 0.0216 0.0641 0.0632
Schistosoma mansoni methylthioadenosine phosphorylase 0.1016 0.3454 0.3448
Schistosoma mansoni shk1 kinase-binding protein 0.0055 0.0074 0.0064
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0088 0.0191 0.0168
Schistosoma mansoni adenosylhomocysteinase 0.0528 0.1737 0.1729
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1783
Mycobacterium tuberculosis Inorganic polyphosphate/ATP-NAD kinase PpnK (poly(P)/ATP NAD kinase) 0.0319 0.1002 0.3446
Brugia malayi PWWP domain containing protein 0.0176 0.05 0.049
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0128 0.0332 0.0264
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.007 0.0133
Schistosoma mansoni hepatoma derived growth factor 0.0176 0.05 0.0491
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0104 0.0249 0.05
Onchocerca volvulus 0.0324 0.1022 0.2077
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0188 0.0544 0.1094
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0479
Schistosoma mansoni SET domain protein 0.0197 0.0575 0.0566
Trypanosoma brucei uridine phosphorylase 0.0188 0.0544 0.1562
Brugia malayi follicle stimulating hormone receptor 0.0216 0.0641 0.0632
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0071 0.0133 0.037
Loa Loa (eye worm) IMP dehydrogenase 1 0.0088 0.0191 0.018
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1016 0.3454 1
Echinococcus granulosus g protein coupled receptor 0.0216 0.0641 0.0619
Echinococcus granulosus PWWP domain containing protein 2A 0.0176 0.05 0.0478
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0053 0.007 0.0116
Schistosoma mansoni protein arginine n-methyltransferase 0.0143 0.0386 0.0377
Echinococcus multilocularis allatostatin A receptor 0.0216 0.0641 0.0576
Trypanosoma cruzi spermidine synthase, putative 0.0741 0.2486 0.7192
Brugia malayi orotate phosphoribosyltransferase family protein 0.0071 0.0133 0.0122
Echinococcus multilocularis neuropeptide receptor A26 0.0216 0.0641 0.0576
Leishmania major nucleoside phosphorylase-like protein 0.0188 0.0544 0.1562
Mycobacterium leprae probable uridine phosphorylase 0.0188 0.0544 0.1521
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0161 0.0449 0.0439
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Loa Loa (eye worm) TYRA-2 protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) PWWP domain-containing protein 0.0176 0.05 0.049
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0216 0.0641 0.0632
Treponema pallidum uridine phosphorylase (udp) 0.0188 0.0544 0.3535
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Trypanosoma cruzi spermidine synthase, putative 0.0741 0.2486 0.7192
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Plasmodium falciparum protein arginine N-methyltransferase 5, putative 0.0055 0.0074 0.0125
Trichomonas vaginalis set domain proteins, putative 0.1423 0.4883 1
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0053 0.007 0.0133
Onchocerca volvulus 0.0216 0.0641 0.1295
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus PWWP domain containing protein 2A 0.0176 0.05 0.0478
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0853 0.2879 0.5892
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Schistosoma mansoni myosin xvIII 0.0216 0.0641 0.0632
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0053 0.007 0.006
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0149 0.0407 0.0397
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0149 0.0407 0.1165
Echinococcus granulosus tm gpcr rhodopsin 0.0216 0.0641 0.0619
Loa Loa (eye worm) G-protein coupled receptor 0.0216 0.0641 0.0632
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0061 0.0096 0.0086
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Schistosoma mansoni neuropeptide receptor 0.0216 0.0641 0.0632
Echinococcus granulosus serotonin receptor 0.0216 0.0641 0.0619
Echinococcus granulosus geminin 0.0133 0.0351 0.0328
Loa Loa (eye worm) hypothetical protein 0.0169 0.0477 0.0467
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni histamine h1 receptor 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0216 0.0641 0.1295
Echinococcus granulosus neuropeptide receptor 0.0216 0.0641 0.0619
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0094 0.0211 0.0643
Schistosoma mansoni polybromo-1 0.0073 0.0137 0.0128
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0063 0.0102 0.0032
Leishmania major inosine-5-monophosphate dehydrogenase 0.0088 0.0191 0.0539
Brugia malayi larval opioid receptor 0.0216 0.0641 0.0632
Trypanosoma cruzi hypothetical protein, conserved 0.0176 0.05 0.1436
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0104 0.0249 0.018
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0853 0.2879 0.8332
Schistosoma mansoni hypothetical protein 0.0176 0.05 0.0491
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1783
Brugia malayi MTAP 0.1016 0.3454 0.3448
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0188 0.0544 0.3535
Schistosoma mansoni opsin-like receptor 0.0216 0.0641 0.0632
Schistosoma mansoni hypothetical protein 0.0133 0.0351 0.0341
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0188 0.0544 0.1104
Brugia malayi Serotonin receptor 0.0216 0.0641 0.0632
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0071 0.0133 0.0123
Brugia malayi CXXC zinc finger family protein 0.0591 0.1959 0.195
Schistosoma mansoni hypothetical protein 0.0176 0.05 0.0491
Toxoplasma gondii phosphorylase family protein 0.0188 0.0544 0.112
Echinococcus multilocularis neuropeptide FF receptor 2 0.0216 0.0641 0.0576
Echinococcus granulosus hepatoma derived growth factor protein 0.0176 0.05 0.0478
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0216 0.0641 0.0576
Leishmania major S-adenosylhomocysteine hydrolase 0.0853 0.2879 0.8332
Toxoplasma gondii dihydropteroate synthase 0.0236 0.0712 0.1476
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.087 0.294 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0071 0.0133 0.0122
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0071 0.0133 0.037
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0188 0.0544 0.1846
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0216 0.0641 0.0619
Onchocerca volvulus 0.0216 0.0641 0.1295
Echinococcus granulosus uridine phosphorylase 1 0.0188 0.0544 0.0521
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.004 0.0024 0.0038
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0188 0.0544 0.3535
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0216 0.0641 0.0619
Echinococcus granulosus g-protein coupled receptor 0.0216 0.0641 0.0619
Plasmodium vivax hydroxymethylpterin pyrophosphokinase-dihydropteroate synthetase, putative 0.0236 0.0712 0.2383
Brugia malayi hypothetical protein 0.0176 0.05 0.049
Echinococcus granulosus polybromo 1 0.0073 0.0137 0.0114
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0071 0.0133 0.0063
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0088 0.0191 0.0506
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0149 0.0407 0.034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0216 0.0641 0.0632
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.087 0.294 0.2933
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.004 0.0024 0.0019
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Plasmodium falciparum purine nucleoside phosphorylase 0.0188 0.0544 0.112
Echinococcus multilocularis protein arginine N methyltransferase 5 0.0055 0.0074 0.0004
Loa Loa (eye worm) adenosylhomocysteinase 0.0853 0.2879 0.2872
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0088 0.0191 0.0614
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0049 0.0038
Schistosoma mansoni histone J3 methyltransferase 0.2879 1 1
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0143 0.0386 0.0363
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0176 0.05 0.049
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0053 0.007 0.0188
Toxoplasma gondii bicoid-interacting protein BIN3 0.004 0.0024 0.0019
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0853 0.2879 1
Schistosoma mansoni amine GPCR 0.0216 0.0641 0.0632
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0216 0.0641 0.0576
Loa Loa (eye worm) hypothetical protein 0.0073 0.0137 0.0127
Echinococcus granulosus S adenosylmethionine synthase type 1 0.0101 0.0238 0.0215
Plasmodium vivax orotidine 5'-phosphate decarboxylase, putative 0.006 0.0093 0.0267
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0737
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis geminin 0.0133 0.0351 0.0283
Echinococcus granulosus equilibrative nucleoside transporter 0.0104 0.0249 0.0226
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0094 0.0211 0.0597
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus spermidine synthase 0.0741 0.2486 0.2468
Schistosoma mansoni hypothetical protein 0.0044 0.0038 0.0028
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0176 0.05 0.1436
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.034 0.1077 0.3633
Loa Loa (eye worm) hypothetical protein 0.1512 0.5197 0.5192
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0088 0.0191 0.018
Toxoplasma gondii adenosylhomocysteinase, putative 0.0853 0.2879 0.6065
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus granulosus neuropeptide Y receptor 0.0216 0.0641 0.0619
Echinococcus multilocularis PWWP domain containing protein 2A 0.0176 0.05 0.0434
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0104 0.0249 0.0489
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0216 0.0641 0.0632
Echinococcus multilocularis g-protein coupled receptor 0.0216 0.0641 0.0576
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0083 0.0172 0.0453
Echinococcus granulosus alpha 1A adrenergic receptor 0.0216 0.0641 0.0619
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Entamoeba histolytica hypothetical protein 0.0094 0.0211 0.0643
Toxoplasma gondii DNA methyltransferase 2, putative 0.087 0.294 0.6193
Brugia malayi Serotonin receptor 0.0216 0.0641 0.0632
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0216 0.0641 0.0619
Loa Loa (eye worm) neuropeptide F receptor 0.0216 0.0641 0.0632
Loa Loa (eye worm) melatonin receptor type 1A 0.0216 0.0641 0.0632
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0073 0.0137 0.0128
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0104 0.0249 0.0239
Loa Loa (eye worm) SET domain-containing protein 0.0128 0.0332 0.0322
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0216 0.0641 0.0576
Mycobacterium ulcerans orotidine 5'-phosphate decarboxylase 0.006 0.0093 0.0225
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0853 0.2879 0.8236
Schistosoma mansoni methylthioadenosine phosphorylase 0.1016 0.3454 0.3448
Echinococcus granulosus dro:myosuppressin receptor 0.0216 0.0641 0.0619
Echinococcus multilocularis purine nucleoside phosphorylase 0.0188 0.0544 0.0477
Schistosoma mansoni adenosylhomocysteinase 0.0528 0.1737 0.1729
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi hypothetical protein 0.0104 0.0249 0.0239
Echinococcus multilocularis NAD kinase 0.0347 0.1102 0.1039
Echinococcus multilocularis G protein coupled receptor 139 0.0216 0.0641 0.0576
Brugia malayi Adenosylhomocysteinase 0.0853 0.2879 0.2872
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Brugia malayi SET domain containing protein 0.0094 0.0212 0.0202
Brugia malayi Pre-SET motif family protein 0.0191 0.0554 0.0544
Leishmania major histone-lysine N-methyltransferase, putative 0.0365 0.1167 0.3368
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Brugia malayi SET domain containing protein 0.0128 0.0332 0.0322
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0094 0.0211 0.0597
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0042 0.0029 0.004
Leishmania major arginine N-methyltransferase-like protein 0.0053 0.007 0.0188
Wolbachia endosymbiont of Brugia malayi S-adenosylmethionine synthetase 0.0101 0.0238 1
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0737
Loa Loa (eye worm) hypothetical protein 0.0253 0.0772 0.0763
Mycobacterium leprae Inorganic polyphosphate/ATP-NAD kinase PpnK (Poly(P)/ATP NAD kinase) 0.0319 0.1002 0.2838
Toxoplasma gondii Purine nucleoside phosphorylase 0.0188 0.0544 0.112
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0088 0.0191 0.0539
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0216 0.0641 0.0632
Leishmania major S-adenosylmethionine synthetase 0.0101 0.0238 0.0677
Schistosoma mansoni biogenic amine receptor 0.0216 0.0641 0.0632
Schistosoma mansoni biogenic amine (5HT) receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis sex peptide receptor 0.0216 0.0641 0.0576
Echinococcus granulosus bromo adjacent y domain containing 1 0.0073 0.0137 0.0114
Brugia malayi Dopamine receptor protein 1 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni cpg binding protein 0.0591 0.1959 0.1951
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0216 0.0641 0.0576
Loa Loa (eye worm) neuropeptide F receptor 0.0216 0.0641 0.0632
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0046 0.0044 0.0085
Echinococcus multilocularis metastasis associated protein MTA1 0.0073 0.0137 0.0068
Echinococcus multilocularis adenosylhomocysteinase 0.0853 0.2879 0.2829
Plasmodium falciparum orotidine 5'-phosphate decarboxylase 0.006 0.0093 0.0165
Schistosoma mansoni methylthioadenosine phosphorylase 0.0188 0.0544 0.0534
Brugia malayi polybromodomain protein 0.0073 0.0137 0.0127
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0216 0.0641 0.0632
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0216 0.0641 0.0632
Echinococcus granulosus purine nucleoside phosphorylase 0.0188 0.0544 0.0521
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0188 0.0544 0.3535
Leishmania major S-adenosylmethionine synthetase 0.0101 0.0238 0.0677
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0094 0.0211 0.0597
Schistosoma mansoni adenosylhomocysteinase 0.0528 0.1737 0.1729
Brugia malayi Pre-SET motif family protein 0.1281 0.4383 0.4377
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Brugia malayi hypothetical protein 0.0253 0.0772 0.0763
Echinococcus multilocularis polybromo 1 0.0073 0.0137 0.0068
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0216 0.0641 0.1295
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Schistosoma mansoni opsin-like receptor 0.0216 0.0641 0.0632
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0216 0.0641 0.0576
Brugia malayi putative neuropeptide receptor NPR1 0.0216 0.0641 0.0632
Schistosoma mansoni amine GPCR 0.0216 0.0641 0.0632
Echinococcus multilocularis rhodopsin orphan GPCR 0.0216 0.0641 0.0576
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.1016 0.3454 1
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0176 0.05 0.1436
Onchocerca volvulus 0.0216 0.0641 0.1295
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0214 0.0634 0.0568
Mycobacterium leprae Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) 0.006 0.0093 0.0225
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0216 0.0641 0.0619
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0104 0.0249 0.05
Chlamydia trachomatis bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase 0.0236 0.0712 1
Onchocerca volvulus 0.0176 0.05 0.1005
Echinococcus granulosus neuropeptide receptor 0.0216 0.0641 0.0619
Echinococcus multilocularis neuropeptide Y receptor 0.0216 0.0641 0.0576
Mycobacterium tuberculosis 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) ( 0.0791 0.2663 0.9245
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0737
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0188 0.0544 0.1846
Schistosoma mansoni adenoreceptor 0.0216 0.0641 0.0632
Brugia malayi Carm1-pending protein 0.0143 0.0386 0.0376
Mycobacterium tuberculosis Hypothetical protein 0.0188 0.0544 0.1846
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0172 0.0488 0.0465
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0828 0.2793 0.9699
Mycobacterium tuberculosis Conserved hypothetical protein 0.0188 0.0544 0.1846
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Schistosoma mansoni jumonji domain containing protein 0.006 0.0092 0.0082
Echinococcus multilocularis neuropeptide Y receptor 0.0216 0.0641 0.0576
Trichomonas vaginalis conserved hypothetical protein 0.0188 0.0544 0.1104
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0216 0.0641 0.0632
Toxoplasma gondii S-adenosyl methionine synthetase 0.0101 0.0238 0.0474
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0101 0.0238 0.0677
Brugia malayi hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0253 0.0772 0.0763
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0081 0.0168 0.0525
Brugia malayi Dopamine receptor 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0591 0.1959 0.3998
Echinococcus granulosus orexin receptor type 2 0.0216 0.0641 0.0619
Loa Loa (eye worm) G-protein coupled receptor 0.0216 0.0641 0.0632
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0188 0.0544 0.1104
Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 0.0236 0.0712 0.1476
Echinococcus granulosus metastasis associated protein 1 mta1 0.0073 0.0137 0.0114
Schistosoma mansoni enhancer of zeste ezh 0.0606 0.2013 0.2005
Schistosoma mansoni hypothetical protein 0.0133 0.0351 0.0341
Loa Loa (eye worm) hypothetical protein 0.1512 0.5197 0.5192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0216 0.0641 0.0632
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0216 0.0641 0.0632
Schistosoma mansoni hypothetical protein 0.0176 0.05 0.0491
Brugia malayi sulfakinin receptor protein 0.0216 0.0641 0.0632
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0188 0.0544 0.1562
Loa Loa (eye worm) hypothetical protein 0.0216 0.0641 0.0632
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0216 0.0641 0.0632
Trichomonas vaginalis origin recognition complex subunit, putative 0.0073 0.0137 0.0271
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0853 0.2879 0.8236
Schistosoma mansoni cpg binding protein 0.0593 0.1967 0.1959
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0698 0.2336 0.6758
Entamoeba histolytica adenosylhomocysteinase, putative 0.0853 0.2879 0.9792
Echinococcus multilocularis g protein coupled receptor 0.0216 0.0641 0.0576
Schistosoma mansoni opsin-like receptor 0.0216 0.0641 0.0632
Onchocerca volvulus 0.0216 0.0641 0.1295
Echinococcus multilocularis g protein coupled receptor 0.0216 0.0641 0.0576

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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