Detailed information for compound 2073745

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 334.372 | Formula: C19H18N4O2
  • H donors: 1 H acceptors: 4 LogP: 1.69 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1nc2ccncc2c(c1)c1ccncc1)NCC1CCCO1
  • InChi: 1S/C19H18N4O2/c24-19(22-11-14-2-1-9-25-14)18-10-15(13-3-6-20-7-4-13)16-12-21-8-5-17(16)23-18/h3-8,10,12,14H,1-2,9,11H2,(H,22,24)
  • InChiKey: NPAQSLUMSZMPLL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus phd:f box containing protein 0.0016 0.0124 0.0124
Mycobacterium ulcerans ferredoxin reductase 0.0011 0.0036 0.0004
Echinococcus granulosus multidrug resistance protein 1 0.0037 0.0441 0.0441
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Brugia malayi ABC transporter family protein 0.0012 0.0052 0.0096
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0069 0.0939 0.1716
Brugia malayi hypothetical protein 0.0012 0.0052 0.0096
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0048 0.0048
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0069 0.0939 0.163
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0675 0.0675
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0209 0.0339
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0209 0.0339
Plasmodium vivax PST-A protein 0.003 0.0332 0.0559
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.0882 0.1628
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0048 0.0048
Mycobacterium ulcerans hypothetical protein 0.0011 0.0036 0.0004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0048 0.0088
Onchocerca volvulus 0.0011 0.0036 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0209 0.0263
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0053 0.0033
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0561 0.1015
Giardia lamblia MRP-like ABC transporter 0.0012 0.0052 0.0331
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0823 0.1503
Brugia malayi hypothetical protein 0.0024 0.0241 0.0444
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0011 0.0036 0.0004
Giardia lamblia Hypothetical protein 0.0011 0.0046 0.0216
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.1893 0.3598
Brugia malayi multidrug resistance protein 3 0.0037 0.0441 0.0814
Trichomonas vaginalis esterase, putative 0.0069 0.0939 0.1471
Brugia malayi nuclear receptor NHR-88 0.0011 0.0048 0.0089
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0944 0.1761
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.004 0.0483 0.0483
Trichomonas vaginalis penicillin-binding protein, putative 0.0069 0.0939 0.1471
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0209 0.0339
Brugia malayi multidrug resistance related protein 1 0.0012 0.0052 0.0096
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0124 0.0124
Mycobacterium ulcerans esterase/lipase LipP 0.0069 0.0939 0.1753
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0048 0.0088
Trypanosoma brucei DNA polymerase eta, putative 0.0037 0.045 0.0802
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.045 0.083
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0343 0.0579
Loa Loa (eye worm) hypothetical protein 0.0052 0.0675 0.1171
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0215
Trichomonas vaginalis ABC transporter, putative 0.0037 0.0441 0.0661
Brugia malayi MGC83647 protein 0.003 0.0332 0.0612
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0153 0.0193
Echinococcus granulosus dna polymerase kappa 0.007 0.0944 0.0944
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0037 0.0441 0.0765
Mycobacterium tuberculosis Probable dehydrogenase 0.0261 0.388 0.579
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0441 0.0661
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0209 0.0263
Brugia malayi intermediate filament protein 0.0041 0.0502 0.0926
Mycobacterium leprae conserved hypothetical protein 0.0069 0.0939 0.1749
Trichomonas vaginalis abcb9, putative 0.0037 0.0441 0.0661
Giardia lamblia Thioredoxin reductase 0.0011 0.0036 0.004
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.004 0.0483 0.0844
Plasmodium vivax PST-A protein 0.0346 0.5199 0.9753
Onchocerca volvulus 0.0024 0.0241 0.0389
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0012 0.0052 0.003
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0052 0.0052
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0012 0.0052 0.003
Echinococcus granulosus multidrug resistance protein 1 0.0037 0.0441 0.0441
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0241 0.0241
Schistosoma mansoni multidrug resistance protein 0.0037 0.0441 0.0806
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0944 0.1758
Loa Loa (eye worm) cytochrome P450 0.0022 0.0209 0.0363
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0209 0.0339
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0939 0.1749
Echinococcus multilocularis cpg binding protein 0.0016 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0059
Brugia malayi P-glycoprotein-like protein 0.0012 0.0052 0.0096
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0209 0.0263
Plasmodium falciparum multidrug resistance protein 1 0.0037 0.0441 0.0765
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.042 0.2067
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0944 0.1758
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0052 0.0035
Toxoplasma gondii hypothetical protein 0.003 0.0332 0.0559
Loa Loa (eye worm) hypothetical protein 0.0041 0.0502 0.0871
Plasmodium vivax lysophospholipase, putative 0.003 0.0332 0.0559
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0012 0.0052 0.0035
Schistosoma mansoni disulfide oxidoreductase 0.0011 0.0036 0.0066
Entamoeba histolytica P-glycoprotein 5, putative 0.0037 0.0441 0.0765
Treponema pallidum NADH oxidase 0.004 0.0483 0.2407
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0261 0.388 0.579
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Schistosoma mansoni hypothetical protein 0.0279 0.416 0.7599
Schistosoma mansoni inositol monophosphatase 0.0045 0.0561 0.1024
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.1893 0.3596
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.029 0.4327 0.831
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Toxoplasma gondii hypothetical protein 0.0355 0.533 1
Brugia malayi jmjC domain containing protein 0.0016 0.0124 0.0229
Plasmodium falciparum lysophospholipase, putative 0.0346 0.5199 0.9753
Echinococcus multilocularis musashi 0.0041 0.0502 0.0502
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0012 0.0052 0.003
Trichomonas vaginalis abcb9, putative 0.0037 0.0441 0.0661
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0053 0.0033
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0012 0.0052 0.003
Echinococcus multilocularis GPCR, family 2 0.003 0.0341 0.0341
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.081 0.081
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0048 0.0078
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0012 0.0052 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0823 0.1503
Plasmodium vivax glutathione reductase, putative 0.0114 0.1631 0.3012
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0012 0.0052 0.003
Onchocerca volvulus 0.0015 0.0106 0.0172
Echinococcus multilocularis geminin 0.0279 0.416 0.416
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0346 0.5199 0.8394
Schistosoma mansoni hypothetical protein 0.003 0.0341 0.0623
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.1893 0.3596
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Schistosoma mansoni inositol monophosphatase 0.0045 0.0561 0.1024
Schistosoma mansoni hypothetical protein 0.0215 0.3173 0.5797
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0048 0.0089
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0011 0.0036 0.0004
Brugia malayi cytochrome P450 0.0022 0.0209 0.0386
Plasmodium falciparum epoxide hydrolase 2 0.003 0.0332 0.0559
Schistosoma mansoni coup transcription factor 0.0011 0.0048 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0394 0.0693
Leishmania major cytochrome p450-like protein 0.0041 0.0505 0.0908
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.042 0.8585
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.004 0.0483 0.0866
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0046 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0343 0.0579
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0079
Brugia malayi MGC79044 protein 0.003 0.0332 0.0612
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0011 0.0036 0.0003
Leishmania major pentamidine resistance protein 1 0.0012 0.0052 0.003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0053 0.0032
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0053 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0011 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.0019 0.0171 0.0296
Mycobacterium tuberculosis Conserved protein 0.0069 0.0939 0.1363
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0675 0.1233
Plasmodium falciparum BEM46-like protein, putative 0.003 0.0332 0.0559
Echinococcus granulosus abhydrolase domain containing 3 0.003 0.0332 0.0332
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0053 0.0033
Plasmodium falciparum ABC transporter B family member 4, putative 0.0012 0.0052 0.003
Leishmania major p-glycoprotein 0.0037 0.0441 0.0784
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Plasmodium falciparum ABC transporter B family member 3, putative 0.0012 0.0052 0.003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0019 0.0172 0.0318
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0037 0.0441 0.0441
Toxoplasma gondii protein c14orf29, putative 0.003 0.0332 0.0559
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0048 0.0088
Loa Loa (eye worm) ABC transporter 0.0012 0.0052 0.009
Schistosoma mansoni multidrug resistance protein 0.0012 0.0052 0.0095
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Plasmodium falciparum lysophospholipase, putative 0.0346 0.5199 0.9753
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0053 0.0033
Brugia malayi 6-phosphofructokinase 0.0132 0.1899 0.3502
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Echinococcus granulosus Phospholipase carboxylesterase 0.003 0.0332 0.0332
Toxoplasma gondii histone lysine methyltransferase SET1 0.003 0.0343 0.0579
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0209 0.0263
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0241 0.0241
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0037 0.0441 0.0441
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0505 0.0908
Loa Loa (eye worm) hypothetical protein 0.003 0.0332 0.0576
Entamoeba histolytica P-glycoprotein-1 0.0037 0.0441 0.0765
Schistosoma mansoni glutamate synthase 0.0011 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.0037 0.0441 0.0765
Brugia malayi Cytochrome P450 family protein 0.0022 0.0209 0.0386
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.003 0.0332 0.0559
Brugia malayi ABC transporter 0.0012 0.0052 0.0096
Brugia malayi Inositol-1 0.0045 0.0561 0.1034
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0048 0.0078
Plasmodium falciparum ABC transporter B family member 7, putative 0.0012 0.0052 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0069 0.0939 0.1716
Trypanosoma brucei monoglyceride lipase, putative 0.0346 0.5199 1
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0012 0.0052 0.003
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.042 0.0627
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.004 0.0483 1
Plasmodium vivax hypothetical protein, conserved 0.0069 0.0939 0.1706
Mycobacterium ulcerans monoxygenase 0.0011 0.0036 0.0004
Brugia malayi jmjC domain containing protein 0.0062 0.0823 0.1518
Echinococcus multilocularis glutamate synthase 0.0011 0.0036 0.0036
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.003 0.0332 0.0332
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0209 0.0263
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0209 0.0263
Mycobacterium ulcerans hypothetical protein 0.0069 0.0939 0.1753
Plasmodium falciparum glutathione reductase 0.0114 0.1631 0.3012
Entamoeba histolytica multidrug resistance protein, putative 0.0012 0.0052 0.003
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.003 0.0332 0.0573
Trichomonas vaginalis glutamate synthase, putative 0.0011 0.0036 0.0003
Brugia malayi Melibiase family protein 0.0036 0.0426 0.0785
Chlamydia trachomatis hydrolase 0.003 0.0332 0.6619
Onchocerca volvulus 0.0041 0.0502 0.0811
Giardia lamblia Multidrug resistance-associated protein 1 0.0012 0.0052 0.0331
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Echinococcus multilocularis multidrug resistance associated protein 7 0.0012 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.003 0.0332 0.0573
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0011 0.0036 0.0004
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.003 0.0332 0.0484
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0041 0.0502 0.0871
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Echinococcus multilocularis RUN 0.0024 0.0241 0.0241
Echinococcus multilocularis neuropeptide s receptor 0.0659 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0012 0.0052 0.003
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.042 0.0725
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0069 0.0939 0.1363
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.003 0.0332 0.0484
Mycobacterium ulcerans flavoprotein disulfide reductase 0.004 0.0483 0.0869
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0036 0.0435 0.0435
Schistosoma mansoni hypothetical protein 0.0011 0.0036 0.0066
Echinococcus granulosus geminin 0.0279 0.416 0.416
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0675 0.1233
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0343 0.0594
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0209 0.0339
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0547 0.0989
Mycobacterium tuberculosis Probable hydrolase 0.0069 0.0939 0.1363
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0441 0.0661
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.005 0.064 0.064
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0547 0.0989
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0332 0.0576
Plasmodium vivax hypothetical protein, conserved 0.003 0.0332 0.0559
Echinococcus granulosus RUN 0.0024 0.0241 0.0241
Echinococcus granulosus multidrug resistance associated protein 1 0.0012 0.0052 0.0052
Loa Loa (eye worm) CXXC zinc finger family protein 0.0015 0.0106 0.0185
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0048 0.0089
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0209 0.0339
Brugia malayi hypothetical protein 0.001 0.0034 0.0063
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0209 0.0339
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.003 0.0332 0.0559
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.004 0.0483 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0048 0.0089
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0124 0.0227
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.1349 0.2488
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0241 0.0241
Brugia malayi ABC transporter transmembrane region family protein 0.0011 0.0046 0.0084
Loa Loa (eye worm) hypothetical protein 0.004 0.049 0.0851
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.045 0.045
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0209 0.0339
Schistosoma mansoni peptidase 0.003 0.0332 0.0607
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0209 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Schistosoma mansoni glutamate synthase 0.0011 0.0036 0.0066
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0209 0.0339
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0124 0.017
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0261 0.388 0.7444
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0012 0.0052 0.003
Plasmodium falciparum esterase, putative 0.0355 0.533 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1893 0.3596
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0137 0.0137
Plasmodium vivax ABC transporter B family member 5, putative 0.0012 0.0052 0.003
Onchocerca volvulus 0.0069 0.0939 0.1518
Brugia malayi cytoplasmic intermediate filament protein 0.0022 0.0211 0.0389
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0209 0.0263
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0483 0.0866
Mycobacterium tuberculosis Possible lysophospholipase 0.0346 0.5199 0.7776
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0209 0.0339
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.2064 0.2064
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0346 0.5199 0.9753
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0037 0.0441 0.0661
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0022 0.0211 0.0366
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0048 0.0048
Giardia lamblia Glutamate synthase 0.0011 0.0036 0.004
Schistosoma mansoni rab6-interacting 0.0024 0.0241 0.044
Brugia malayi Doublecortin family protein 0.0024 0.0241 0.0444
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0012 0.0052 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0124 0.0227
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0209 0.0339
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.003 0.0332 0.0573
Echinococcus granulosus cytoplasmic intermediate filament protein 0.002 0.0177 0.0177
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0012 0.0052 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0573 0.1039
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0037 0.0441 0.0441
Plasmodium vivax PST-A protein 0.003 0.0332 0.0559
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0441 0.0661
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0561 0.1015
Leishmania major DNA polymerase eta, putative 0.0012 0.0053 0.0033
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.003 0.0332 0.0484
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0054 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0019 0.0172 0.0299
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0172 0.0172
Loa Loa (eye worm) ABC transporter 0.0012 0.0052 0.009
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1893 0.3596
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0483 0.0866
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0011 0.0036 0.0004
Loa Loa (eye worm) programmed cell death 8 0.0011 0.0036 0.0063
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0048 0.0088
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Schistosoma mansoni smdr2 0.0037 0.0441 0.0806
Plasmodium vivax hypothetical protein, conserved 0.003 0.0332 0.0559
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0011 0.0036 0.0036
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0209 0.0335
Echinococcus granulosus dnaJ subfamily B 0.0215 0.3173 0.3173
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0069 0.0939 0.1363
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0341 0.0341
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0561 0.099
Plasmodium vivax lysophospholipase, putative 0.003 0.0332 0.0559
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0332 0.0484
Echinococcus granulosus GPCR family 2 0.003 0.0341 0.0341
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0012 0.0052 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0053 0.0032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0054 0.0701 0.128
Schistosoma mansoni multidrug resistance protein 0.0011 0.0046 0.0084
Loa Loa (eye worm) hypothetical protein 0.0017 0.0133 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0355 0.533 0.8606
Trypanosoma cruzi DNA polymerase eta, putative 0.0012 0.0053 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0675 0.1233
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0012 0.0052 0.0095
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0346 0.5199 0.8394
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0505 0.0908
Trichomonas vaginalis conserved hypothetical protein 0.0346 0.5199 0.8394
Plasmodium falciparum ABC transporter B family member 5, putative 0.0012 0.0052 0.003
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1893 0.3507
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.002 0.0177 0.0177
Mycobacterium tuberculosis Conserved protein 0.0069 0.0939 0.1363
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0561 0.0855
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0053 0.0033
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Echinococcus granulosus dna polymerase eta 0.0037 0.045 0.045
Schistosoma mansoni hypothetical protein 0.0022 0.0209 0.0382
Brugia malayi Cytochrome P450 family protein 0.0041 0.0505 0.0931
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0332 0.0484
Onchocerca volvulus 0.0052 0.0675 0.1091
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0209 0.0263
Onchocerca volvulus 0.0162 0.2358 0.3811
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0011 0.0036 0.0004
Brugia malayi Sulfatase family protein 0.001 0.0034 0.0063
Entamoeba histolytica hypothetical protein 0.003 0.0332 0.0559
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Loa Loa (eye worm) hypothetical protein 0.0096 0.1349 0.234
Leishmania major hypothetical protein, conserved 0.0016 0.0124 0.017
Plasmodium vivax ABC transporter B family member 3, putative 0.0012 0.0052 0.003
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.042 0.0725
Echinococcus multilocularis multidrug resistance protein 1 0.0037 0.0441 0.0441
Trichomonas vaginalis taga, putative 0.0037 0.0441 0.0661
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0011 0.0036 0.004
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0209 0.0339
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0241 0.0241
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.004 0.0483 0.0891
Loa Loa (eye worm) glutathione reductase 0.0114 0.1631 0.2829
Toxoplasma gondii hypothetical protein 0.003 0.0332 0.0559
Brugia malayi Protein C20orf22 0.003 0.0332 0.0612
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0054 0.0701 0.128
Plasmodium falciparum esterase, putative 0.0355 0.533 1
Echinococcus granulosus ATP binding cassette sub family B 0.0012 0.0052 0.0052
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0441 0.0661
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0011 0.0036 0.0036
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0037 0.0441 0.0441
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0052 0.0675 0.0675
Mycobacterium leprae putative cytochrome p450 0.0022 0.0209 0.0335
Plasmodium vivax ABC transporter B family member 4, putative 0.0012 0.0052 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0053 0.0033
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0011 0.0036 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0341 0.0592
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Brugia malayi glutathione reductase 0.0114 0.1631 0.3007
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0012 0.0052 0.003
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0209 0.0339
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0341 0.0629
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0483 0.0866
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0209 0.0335
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0124 0.0227
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0012 0.0052 0.009
Brugia malayi ABC transporter 0.0011 0.0046 0.0084
Onchocerca volvulus 0.0411 0.6188 1
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.003 0.0332 0.0484
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0011 0.0036 0.0036
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0346 0.5199 0.8394
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0037 0.0441 0.0441
Brugia malayi beta-lactamase 0.0069 0.0939 0.1733
Entamoeba histolytica P-glycoprotein 6, putative 0.0012 0.0052 0.003
Brugia malayi glutamate synthase 0.0011 0.0036 0.0067
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1893 0.302
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0355 0.533 1
Trypanosoma brucei unspecified product 0.0026 0.0272 0.0456
Leishmania major monoglyceride lipase, putative 0.0346 0.5199 1
Entamoeba histolytica hypothetical protein 0.003 0.0332 0.0559
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0124 0.0124
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0048 0.0088
Entamoeba histolytica P-glycoprotein-2, putative 0.0037 0.0441 0.0765
Leishmania major DNA polymerase eta, putative 0.0037 0.045 0.0802
Schistosoma mansoni hypothetical protein 0.003 0.0341 0.0623
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0048 0.0048
Brugia malayi jmjC domain containing protein 0.0016 0.0124 0.0229
Plasmodium vivax PST-A protein 0.003 0.0332 0.0559
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.003 0.0332 0.0607
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0048 0.0048
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0346 0.5199 0.8394
Trypanosoma brucei multidrug resistance protein E 0.0012 0.0052 0.003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0341 0.0341
Echinococcus granulosus monoacylglycerol lipase abhd12 0.003 0.0332 0.0332
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0341 0.0341
Leishmania major DNA polymerase kappa, putative 0.0012 0.0053 0.0033
Plasmodium vivax unspecified product 0.0355 0.533 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0036 0.0426 0.0777
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0823 0.1428
Loa Loa (eye worm) hypothetical protein 0.0024 0.0241 0.0418
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Echinococcus multilocularis thioredoxin glutathione reductase 0.0114 0.1631 0.1631
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0939 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0048 0.0089
Echinococcus granulosus lamin dm0 0.0041 0.0502 0.0502
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0012 0.0052 0.0299
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0209 0.0339
Brugia malayi Pre-SET motif family protein 0.0361 0.5422 1
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.003 0.0332 0.0484
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Brugia malayi jmjC domain containing protein 0.0016 0.0124 0.0229
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0048 0.0084
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.003 0.0332 0.0573
Schistosoma mansoni hypothetical protein 0.0014 0.0085 0.0155
Trypanosoma cruzi serine peptidase, putative 0.003 0.0332 0.0573
Brugia malayi ABC transporter family protein 0.0037 0.0441 0.0814
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0048 0.0048
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.042 0.0725
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0048 0.0048
Echinococcus multilocularis multidrug resistance protein 1 0.0037 0.0441 0.0441
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0124 0.0124
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.045 0.0823
Entamoeba histolytica P-glycoprotein-2 0.0037 0.0441 0.0765
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Schistosoma mansoni loxhd1 0.0024 0.0241 0.044
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1893 0.3507
Plasmodium vivax alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0241 0.0241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0124 0.0124
Schistosoma mansoni hypothetical protein 0.003 0.0341 0.0623
Schistosoma mansoni polycystin 1-related 0.0024 0.0241 0.044
Leishmania major hypothetical protein, conserved 0.003 0.0332 0.0573
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.004 0.0483 0.0844
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0209 0.0335
Mycobacterium ulcerans lipase LipD 0.0069 0.0939 0.1753
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0286 0.4271 0.7408
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0346 0.5199 0.8394
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0209 0.0327
Trichomonas vaginalis abcb9, putative 0.0037 0.0441 0.0661
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.003 0.0332 0.0573
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0011 0.0036 0.0004
Loa Loa (eye worm) hypothetical protein 0.0037 0.0441 0.0765
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1893 0.302
Loa Loa (eye worm) intermediate filament protein 0.0041 0.0502 0.0871
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0209 0.0339
Echinococcus granulosus abhydrolase domain containing protein 13 0.003 0.0332 0.0332
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0085 0.0085
Plasmodium vivax alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0124 0.0215
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0048 0.0088
Brugia malayi ABC transporter family protein 0.0012 0.0052 0.0096
Echinococcus multilocularis dna polymerase eta 0.0037 0.045 0.045
Echinococcus multilocularis dna polymerase kappa 0.007 0.0944 0.0944
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.003 0.0332 0.0607
Schistosoma mansoni jumonji domain containing protein 0.0061 0.081 0.1479
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0012 0.0052 0.003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0048 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0048 0.0089
Toxoplasma gondii ABC transporter family protein 0.0012 0.0052 0.003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0048 0.0048
Onchocerca volvulus 0.0069 0.0939 0.1518
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0054 0.0701 0.128
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0048 0.0048
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0209 0.0263
Loa Loa (eye worm) hypothetical protein 0.0383 0.5765 1
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0241 0.0418
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0209 0.0263
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0395 0.0722
Plasmodium falciparum multidrug resistance protein 2 0.0012 0.0052 0.003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0505 0.0911
Toxoplasma gondii melibiase subfamily protein 0.0054 0.0701 0.1255
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.081 0.081
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0209 0.0335
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0361 0.5422 0.9406
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0012 0.0052 0.003
Echinococcus multilocularis abhydrolase domain containing 3 0.003 0.0332 0.0332
Entamoeba histolytica hypothetical protein 0.0012 0.0052 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0048 0.0084
Entamoeba histolytica ATP-binding cassette protein, putative 0.0012 0.0052 0.003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0241 0.0241
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0052 0.0035
Plasmodium vivax unspecified product 0.003 0.0332 0.0559
Brugia malayi hypothetical protein 0.0024 0.0241 0.0444
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0346 0.5199 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0209 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0124 0.0215
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0048 0.0048
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0048 0.0088
Mycobacterium ulcerans hypothetical protein 0.003 0.0332 0.0577
Echinococcus granulosus thioredoxin glutathione reductase 0.0114 0.1631 0.1631
Plasmodium vivax multidrug resistance protein 2, putative 0.0012 0.0052 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0124 0.0124
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0939 0.1749
Echinococcus multilocularis dnaJ subfamily B 0.0215 0.3173 0.3173
Schistosoma mansoni multidrug resistance protein 0.0037 0.0441 0.0806
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Mycobacterium tuberculosis Probable reductase 0.0261 0.388 0.579
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0209 0.0339
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0037 0.0441 0.0441
Toxoplasma gondii ABC transporter, putative 0.0012 0.0052 0.003
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0124 0.0124
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0048 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0048 0.0084
Entamoeba histolytica P-glycoprotein-2 0.0037 0.0441 0.0765
Mycobacterium leprae Probable lipase LipE 0.0069 0.0939 0.1749
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.1893 0.1893
Mycobacterium ulcerans hypothetical protein 0.0346 0.5199 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0053 0.0033
Schistosoma mansoni intermediate filament proteins 0.0041 0.0502 0.0917
Toxoplasma gondii peptidase S15, putative 0.003 0.0332 0.0559
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0124 0.0166
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.004 0.0483 0.0866
Echinococcus multilocularis lamin dm0 0.0041 0.0502 0.0502
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.02 0.0365
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0209 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0012 0.0052 0.003
Entamoeba histolytica ATP-binding cassette protein, putative 0.0012 0.0052 0.003
Echinococcus granulosus glutamate synthase 0.0011 0.0036 0.0036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0019 0.0166 0.0288
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0018 0.0153 0.0193
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0052 0.0052
Schistosoma mansoni glutamate synthase 0.0011 0.0036 0.0066
Trypanosoma brucei trypanothione reductase 0.0114 0.1631 0.3088
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0048 0.0089
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.029 0.4327 0.6462
Schistosoma mansoni multidrug resistance protein 0.0012 0.0052 0.0095
Brugia malayi Cytochrome P450 family protein 0.0041 0.0505 0.0931
Chlamydia trachomatis acyltransferase family protein 0.003 0.0332 0.6619
Entamoeba histolytica ABC transporter, putative 0.0012 0.0052 0.003
Echinococcus multilocularis beta LACTamase domain containing family member 0.0069 0.0939 0.0939
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0012 0.0052 0.0299
Plasmodium falciparum lysophospholipase, putative 0.003 0.0332 0.0559
Loa Loa (eye worm) hypothetical protein 0.003 0.0332 0.0576
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.004 0.0483 0.0866
Brugia malayi follicle stimulating hormone receptor 0.0286 0.4271 0.7876
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0036 0.0426 0.0636
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0048 0.0048
Plasmodium falciparum thioredoxin reductase 0.004 0.0483 0.0844
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0011 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0029 0.0322 0.0593
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.045 0.0781
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.042 0.0725
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.003 0.0332 0.0573
Trypanosoma brucei unspecified product 0.0026 0.0272 0.0456
Echinococcus granulosus multidrug resistance protein 1 0.0026 0.027 0.027
Mycobacterium tuberculosis Conserved hypothetical protein 0.003 0.0332 0.0449
Plasmodium falciparum exported lipase 1 0.003 0.0332 0.0559
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0011 0.0036 0.0063
Plasmodium vivax hypothetical protein, conserved 0.003 0.0332 0.0559
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0209 0.0263
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Plasmodium vivax SET domain protein, putative 0.0052 0.0675 0.1206
Brugia malayi hypothetical protein 0.0162 0.2358 0.435
Loa Loa (eye worm) hypothetical protein 0.002 0.0177 0.0308
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0011 0.0036 0.0036
Leishmania major DNA damage repair protein, putative 0.0012 0.0053 0.0033
Trypanosoma brucei unspecified product 0.0062 0.0821 0.1521
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Brugia malayi hypothetical protein 0.0147 0.2135 0.3937
Brugia malayi CXXC zinc finger family protein 0.0015 0.0106 0.0196
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0346 0.5199 0.8394
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0241 0.0386
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1893 0.3284
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0124 0.0227
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0069 0.0939 0.1363
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0054 0.0701 0.0701
Toxoplasma gondii thioredoxin reductase 0.0114 0.1631 0.3012
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0037 0.0441 0.9058
Brugia malayi phosphofructokinase 0.0131 0.1893 0.3491
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0944 0.1758
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0011 0.0036 0.0003
Plasmodium falciparum multidrug resistance-associated protein 2 0.0012 0.0052 0.003
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0011 0.0036 0.0003
Brugia malayi Thioredoxin reductase 0.0114 0.1631 0.3007
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0048 0.0088
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.004 0.0483 0.0866
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0048 0.0084
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.003 0.0332 0.0559
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0052 0.0029
Echinococcus granulosus multidrug resistance protein 1 0.0037 0.0441 0.0441
Trypanosoma brucei p-glycoprotein 0.0012 0.0052 0.003
Onchocerca volvulus 0.0024 0.0241 0.0389
Toxoplasma gondii phospholipase 0.003 0.0332 0.0559
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0561 0.0561
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.042 0.0725
Schistosoma mansoni cpg binding protein 0.0016 0.012 0.0218
Onchocerca volvulus 0.0041 0.0502 0.0811
Onchocerca volvulus 0.0011 0.0048 0.0078
Brugia malayi beta-lactamase family protein 0.0069 0.0939 0.1733
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.007 0.0944 0.1479
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0036 0.0426 0.0777
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0048 0.0084
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0011 0.0036 0.0004
Onchocerca volvulus 0.0037 0.0441 0.0713
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0209 0.0263
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0124 0.017
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.004 0.0483 0.0869
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0489 0.0876
Brugia malayi polk-prov protein 0.0044 0.0547 0.1009
Loa Loa (eye worm) hypothetical protein 0.0044 0.0547 0.0949
Leishmania major trypanothione reductase 0.0114 0.1631 0.3088
Echinococcus granulosus multidrug resistance associated protein 7 0.0012 0.0052 0.0052
Plasmodium vivax ABC transporter B family member 7, putative 0.0012 0.0052 0.003
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0209 0.0339
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0939 0.1749
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0012 0.0052 0.003
Echinococcus multilocularis Phospholipase carboxylesterase 0.003 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0394 0.0693
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0053 0.0033
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0011 0.0036 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0046 0.0019
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0343 0.0579
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.02 0.0365
Giardia lamblia NADH oxidase lateral transfer candidate 0.004 0.0483 0.8337
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0012 0.0052 0.003
Echinococcus granulosus lamin 0.0041 0.0502 0.0502
Leishmania major cytochrome p450-like protein 0.0022 0.0209 0.0335
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0046 0.0019
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0241 0.0386
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0483 0.8525
Leishmania major ABC-thiol transporter 0.0012 0.0052 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0069 0.0939 0.1363
Echinococcus granulosus beta LACTamase domain containing family member 0.0069 0.0939 0.0939
Mycobacterium ulcerans hypothetical protein 0.0012 0.0053 0.0037
Plasmodium falciparum multidrug resistance-associated protein 1 0.0012 0.0052 0.003
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0053 0.0098
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0209 0.0339
Brugia malayi jmjC domain containing protein 0.0061 0.081 0.1493
Plasmodium vivax PST-A protein 0.003 0.0332 0.0559
Giardia lamblia DNA damage repair protein 0.0012 0.0053 0.0358
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0124 0.0227
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0069 0.0939 0.1753
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0048 0.0088
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0332 0.0484
Plasmodium falciparum alpha/beta-hydrolase, putative 0.003 0.0332 0.0559
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0012 0.0052 0.0035
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0052 0.0052
Mycobacterium tuberculosis Probable oxidoreductase 0.029 0.4327 0.6462
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0011 0.0046 0.0084
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0505 0.0876
Plasmodium falciparum thioredoxin reductase 0.0114 0.1631 0.3012
Schistosoma mansoni lamin 0.0041 0.0502 0.0917
Loa Loa (eye worm) hypothetical protein 0.003 0.0332 0.0576
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0505 0.0908
Mycobacterium tuberculosis Probable lipase LipD 0.0069 0.0939 0.1363
Plasmodium vivax JmjC domain containing protein 0.0016 0.0124 0.0166
Giardia lamblia ABC transporter, putative 0.0012 0.0052 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Loa Loa (eye worm) inositol-1 0.0045 0.0561 0.0972
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0124 0.017
Schistosoma mansoni cpg binding protein 0.0015 0.0106 0.0194
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0012 0.0052 0.003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0442 0.6676 1
Echinococcus multilocularis neuropeptide receptor A26 0.0659 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0012 0.0052 0.0052
Trichomonas vaginalis penicillin-binding protein, putative 0.0069 0.0939 0.1471
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0261 0.388 0.579
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0048 0.0048
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0561 0.1015
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0114 0.1631 0.2403
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0037 0.0441 0.0784
Brugia malayi Latrophilin receptor protein 2 0.003 0.0341 0.0629
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1893 0.3458
Brugia malayi Cytochrome P450 family protein 0.0022 0.0209 0.0386
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0209 0.0263
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0209 0.0263
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0012 0.0052 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0048 0.0089
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0944 0.1761
Toxoplasma gondii hypothetical protein 0.003 0.0332 0.0559
Schistosoma mansoni hypothetical protein 0.0024 0.0241 0.044
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.029 0.4327 0.6462
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0069 0.0939 0.1733
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.045 0.083
Schistosoma mansoni DNA polymerase eta 0.0037 0.045 0.0823
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.045 0.0802
Echinococcus granulosus multidrug resistance protein 1 0.0026 0.027 0.027
Trichomonas vaginalis glutamate synthase, putative 0.0011 0.0036 0.0003
Brugia malayi steroid hormone receptor 0.0011 0.0048 0.0089
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0048 0.0088
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.003 0.0332 0.0484
Trypanosoma cruzi serine peptidase, putative 0.003 0.0332 0.0573
Loa Loa (eye worm) phosphofructokinase 0.0131 0.1893 0.3284
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0011 0.0036 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0011 0.0036 0.0067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0048 0.0048
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.004 0.0483 0.0844
Trichomonas vaginalis ABC transporter, putative 0.0037 0.0441 0.0661
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.009
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1893 0.3284
Echinococcus multilocularis 0.0012 0.0052 0.0052
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.004 0.0483 0.8525
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1893 0.3458
Loa Loa (eye worm) hypothetical protein 0.0019 0.0166 0.0288
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0505 0.0876
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0346 0.5199 0.8394
Echinococcus multilocularis 0.0022 0.0209 0.0209
Plasmodium falciparum glutathione reductase 0.004 0.0483 0.0844
Mycobacterium ulcerans hydrolase 0.003 0.0332 0.0577
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0124 0.0124
Brugia malayi ecdysteroid receptor 0.0011 0.0048 0.0089
Plasmodium vivax thioredoxin reductase, putative 0.0114 0.1631 0.3012
Onchocerca volvulus 0.0069 0.0939 0.1518
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0048 0.0048
Schistosoma mansoni multidrug resistance protein 0.0012 0.0052 0.0095
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.004 0.0483 0.0483
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0561 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.042 0.0725
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0011 0.0036 0.0067
Trichomonas vaginalis ABC transporter, putative 0.0037 0.0441 0.0661
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0048 0.0089
Leishmania major p-glycoprotein e 0.0012 0.0052 0.003
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0343 0.0594
Loa Loa (eye worm) hypothetical protein 0.0066 0.0882 0.1531
Plasmodium falciparum lysophospholipase, putative 0.0355 0.533 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.004 0.0483 0.0883
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0053 0.0033
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0011 0.0036 0.0003
Brugia malayi beta-lactamase family protein 0.0069 0.0939 0.1733
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0011 0.0036 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0944 0.1758
Brugia malayi ABC transporter family protein 0.0012 0.0052 0.0096
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0944 0.1758
Schistosoma mansoni sulfide quinone reductase 0.0011 0.0036 0.0066
Trichomonas vaginalis set domain proteins, putative 0.0411 0.6188 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0675 0.1233
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0011 0.0036 0.0003
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0037 0.0441 0.0765
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0059
Plasmodium vivax lysophospholipase, putative 0.0355 0.533 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0332 0.0576
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.003 0.0332 0.0559
Loa Loa (eye worm) ABC transporter 0.0012 0.0052 0.009
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0209 0.0263
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.003 0.0332 0.0573
Loa Loa (eye worm) beta-lactamase 0.0069 0.0939 0.163
Trichomonas vaginalis mercuric reductase, putative 0.004 0.0483 0.073
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.1893 0.2798
Echinococcus multilocularis multidrug resistance protein 1 0.0026 0.027 0.027
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0045 0.0573 0.0811
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0052 0.003
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0037 0.0441 0.0661
Trichomonas vaginalis DNA polymerase eta, putative 0.007 0.0944 0.1479
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0046 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.009
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.045 0.045
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0037 0.0441 0.0613
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0048 0.0089
Giardia lamblia DINP protein human, muc B family 0.0045 0.0573 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0435 0.0755
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0048 0.0089
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.002 0.0176 0.0264
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0037 0.0441 0.0441
Trypanosoma cruzi multidrug resistance protein E, putative 0.0012 0.0052 0.003
Brugia malayi hypothetical protein 0.003 0.0343 0.0632
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0346 0.5199 0.9753
Echinococcus granulosus ATP binding cassette sub family B 0.0011 0.0046 0.0046
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0085 0.0085
Leishmania major DNA polymerase kappa, putative 0.0045 0.0573 0.1039
Entamoeba histolytica P-glyco protein 6, putative 0.0037 0.0441 0.0765
Schistosoma mansoni lipoxygenase 0.0142 0.2064 0.3771
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0048 0.0089
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0011 0.0036 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0561 0.1015
Mycobacterium ulcerans dehydrogenase 0.0011 0.0036 0.0004
Schistosoma mansoni multidrug resistance protein 0.0037 0.0441 0.0806
Mycobacterium ulcerans beta-lactamase 0.0069 0.0939 0.1753
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0124 0.0166
Leishmania major hypothetical protein, conserved 0.0069 0.0939 0.1749
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0209 0.0263
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0821 0.1521
Trypanosoma brucei monoglyceride lipase, putative 0.0346 0.5199 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0209 0.0263
Brugia malayi MH2 domain containing protein 0.0106 0.1507 0.278
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Plasmodium falciparum ABC transporter B family member 6, putative 0.0012 0.0052 0.003
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0137 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0048 0.0089
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Leishmania major dihydrolipoamide dehydrogenase, putative 0.004 0.0483 0.0866
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0012 0.0052 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.045 0.0781
Loa Loa (eye worm) thioredoxin reductase 0.0114 0.1631 0.2829
Trichomonas vaginalis apoptosis inducing factor, putative 0.0011 0.0036 0.0003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0037 0.0441 0.0661
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0048 0.0048
Plasmodium falciparum exported lipase 2 0.003 0.0332 0.0559
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0011 0.0036 0.0036
Leishmania major cytochrome p450-like protein 0.0022 0.0209 0.0335
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0052 0.0675 0.1206
Plasmodium falciparum lysophospholipase, putative 0.0346 0.5199 0.9753
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.004 0.0483 0.0866
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0011 0.0036 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0029 0.0322 0.0593
Trichomonas vaginalis ABC transporter, putative 0.0037 0.0441 0.0661
Schistosoma mansoni smdr1 0.0012 0.0052 0.0095
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0209 0.0339
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0037 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0079
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0037 0.0441 0.0765
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.042 0.0627
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.042 0.0725
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0046 0.0018
Brugia malayi hypothetical protein 0.002 0.0177 0.0326
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0561 0.099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0241 0.0418
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0052 0.0035
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0011 0.0036 0.0036
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0124 0.0166
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0011 0.0036 0.0003
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0011 0.0036 0.0036
Brugia malayi Pre-SET motif family protein 0.0052 0.0675 0.1245
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Brugia malayi ABC transporter transmembrane region family protein 0.0012 0.0052 0.0096
Schistosoma mansoni hypothetical protein 0.0066 0.0882 0.1612
Toxoplasma gondii NADPH-glutathione reductase 0.004 0.0483 0.0844
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.009
Schistosoma mansoni hypothetical protein 0.003 0.0341 0.0623
Schistosoma mansoni multidrug resistance protein 0.0012 0.0052 0.0095
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.1349 0.2488
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0048 0.0089
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0209 0.0335
Brugia malayi nuclear hormone receptor 0.0011 0.0048 0.0089
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0823 0.0823
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0209 0.0363
Mycobacterium tuberculosis Conserved protein 0.0069 0.0939 0.1363
Schistosoma mansoni lipoxygenase 0.01 0.1406 0.2568
Loa Loa (eye worm) hypothetical protein 0.0069 0.0939 0.163
Loa Loa (eye worm) hypothetical protein 0.0036 0.0426 0.0738
Loa Loa (eye worm) MH2 domain-containing protein 0.0106 0.1507 0.2614
Mycobacterium ulcerans hypothetical protein 0.003 0.0332 0.0577
Plasmodium vivax ABC transporter B family member 6, putative 0.0012 0.0052 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0944 0.1758
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0675 0.0675
Echinococcus multilocularis lamin 0.0041 0.0502 0.0502
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0037 0.0441 0.0661
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0048 0.0084
Plasmodium falciparum prodrug activation and resistance esterase 0.003 0.0332 0.0559
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0054 0.0701 0.0701
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0394 0.0693
Mycobacterium tuberculosis Probable lipase LipE 0.0069 0.0939 0.1363
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0489 0.0684
Plasmodium falciparum esterase, putative 0.0346 0.5199 0.9753
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.1893 0.1893
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0261 0.388 0.579
Loa Loa (eye worm) hypothetical protein 0.0011 0.0036 0.0063
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0011 0.0036 0.0036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0561 0.0855
Loa Loa (eye worm) hypothetical protein 0.003 0.0343 0.0595
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0011 0.0046 0.0216
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.004 0.0483 0.0676
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.003 0.0332 0.0573
Entamoeba histolytica P-glycoprotein-5 0.0037 0.0441 0.0765
Echinococcus multilocularis ATP binding cassette sub family B 0.0036 0.0435 0.0435
Entamoeba histolytica ;Alias 0.003 0.0332 0.0559
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0561 0.1019
Mycobacterium ulcerans NADH dehydrogenase 0.0011 0.0036 0.0004
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0209 0.0335
Schistosoma mansoni rab6-interacting 0.0024 0.0241 0.044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0037 0.0441 0.0441
Trichomonas vaginalis glutathione reductase, putative 0.004 0.0483 0.073
Plasmodium falciparum alpha/beta hydrolase, putative 0.003 0.0332 0.0559
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0048 0.0088
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1893 0.302
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.1349 0.234
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.045 0.0823
Leishmania major hypothetical protein, conserved 0.003 0.0343 0.0594
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0053 0.0032
Schistosoma mansoni lamin 0.0041 0.0502 0.0917
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0012 0.0052 0.003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.2064 0.2064
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.042 0.8585
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0172 0.0172
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.003 0.0332 0.0573
Mycobacterium ulcerans glutamate synthase subunit beta 0.0011 0.0036 0.0004
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.042 0.7163
Echinococcus granulosus neuropeptide receptor A26 0.0659 1 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0011 0.0046 0.0216
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1893 0.302
Schistosoma mansoni cytochrome P450 0.0022 0.0209 0.0382
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0048 0.0084
Brugia malayi 6-phosphofructokinase 0.0131 0.1893 0.3491
Entamoeba histolytica P-glycoprotein 6, putative 0.0012 0.0052 0.003
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1893 0.3507
Loa Loa (eye worm) multidrug resistance protein 3 0.0037 0.0441 0.0765
Brugia malayi Intermediate filament tail domain containing protein 0.0041 0.0502 0.0926
Echinococcus multilocularis multidrug resistance associated protein 1 0.0012 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0046 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.0106 0.1507 0.2614
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0939 0.1471
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.081 0.081
Plasmodium vivax PST-A protein 0.003 0.0332 0.0559
Leishmania major acetoin dehydrogenase e3 component-like protein 0.004 0.0483 0.0866
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0209 0.0263
Schistosoma mansoni cpg binding protein 0.0016 0.012 0.0218
Plasmodium vivax multidrug resistance protein 1, putative 0.0037 0.0441 0.0765
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0505 0.0876
Echinococcus granulosus intermediate filament protein 0.0041 0.0502 0.0502
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0124 0.0215
Giardia lamblia Cgi67 serine protease precursor-like protein 0.003 0.0332 0.5532
Mycobacterium ulcerans lysophospholipase 0.0346 0.5199 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0048 0.0088
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.042 0.0725
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0341 0.0592
Brugia malayi ABC transporter transmembrane region family protein 0.0012 0.0052 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0944 0.1758
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0261 0.388 0.579
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.1893 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.045 0.0782
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.001 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0162 0.2358 0.4091
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Schistosoma mansoni hypothetical protein 0.0279 0.416 0.7599
Entamoeba histolytica ATP-binding cassette protein, putative 0.0012 0.0052 0.003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.045 0.0626
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0012 0.0052 0.003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0045 0.0573 0.1039
Toxoplasma gondii phospholipase/carboxylesterase 0.003 0.0332 0.0559
Trichomonas vaginalis D-aminoacylase, putative 0.0069 0.0939 0.1471
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0011 0.0036 0.0067
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0012 0.0052 0.0096
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.004 0.0483 0.0844
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0561 0.0855
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Trypanosoma cruzi monoglyceride lipase, putative 0.0346 0.5199 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0012 0.0052 0.0331
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0048 0.0078
Echinococcus granulosus cpg binding protein 0.0016 0.012 0.012
Schistosoma mansoni multidrug resistance protein 0.0012 0.0052 0.0095
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0052 0.0052
Brugia malayi jmjC domain containing protein 0.0016 0.0124 0.0229
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0048 0.0084
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0054 0.0701 0.128
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0332 0.0484
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0026 0.027 0.0383
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.003 0.0332 0.0573
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0343 0.0579
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0011 0.0036 0.0003
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0011 0.0036 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0037 0.0441 0.0661
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0048 0.0048
Toxoplasma gondii ABC1 family protein 0.0069 0.0939 0.1706
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0561 0.0561
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.004 0.0483 0.0869
Loa Loa (eye worm) hypothetical protein 0.0011 0.0048 0.0084
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0209 0.0209
Trypanosoma cruzi trypanothione reductase, putative 0.0114 0.1631 0.3088
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0343 0.0594
Loa Loa (eye worm) hypothetical protein 0.0016 0.0124 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0048 0.0089

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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