Detailed information for compound 2073760

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 356.462 | Formula: C20H28N4O2
  • H donors: 1 H acceptors: 3 LogP: 1.18 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1CCN(CC1)Cc1c(C2CC2)n(c2c1cccn2)CC(=O)N(C)C
  • InChi: 1S/C20H28N4O2/c1-22(2)18(26)13-24-19(14-5-6-14)17(16-4-3-9-21-20(16)24)12-23-10-7-15(25)8-11-23/h3-4,9,14-15,25H,5-8,10-13H2,1-2H3
  • InChiKey: AKDBSMNBKWNUQQ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Arginase, putative 0.0251 0.3027 1
Echinococcus granulosus neuroligin 0.0137 0.1605 0.1605
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0027 0.0229 0.0991
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.3027 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0035 0.0336 0.0312
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Brugia malayi multidrug resistance related protein 1 0.0027 0.0229 0.0207
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0629 0.1413
Echinococcus granulosus dnaJ subfamily B 0.0468 0.5729 0.5729
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0093 0.0124
Schistosoma mansoni DNA helicase recq1 0.0023 0.0181 0.0181
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0127 0.0986
Brugia malayi Carboxylesterase family protein 0.0137 0.1605 0.1585
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0134 0.011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0059 0.0635 0.1596
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0442 0.0442
Echinococcus granulosus multidrug resistance protein 1 0.0085 0.0953 0.0953
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0446 0.1906
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0229 0.0229
Leishmania major agmatinase-like protein 0.0091 0.1037 0.2392
Loa Loa (eye worm) hypothetical protein 0.0013 0.0065 0.004
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0308 0.0283
Echinococcus multilocularis multidrug resistance associated protein 7 0.0027 0.0229 0.0229
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0027 0.0229 0.0205
Brugia malayi polk-prov protein 0.0027 0.0232 0.0209
Echinococcus granulosus ATP binding cassette sub family G 0.0012 0.0051 0.0051
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0181 0.0482
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Trypanosoma cruzi arginase, putative 0.0091 0.1037 0.2392
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0023 0.0181 0.0436
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0336 0.0545
Entamoeba histolytica P-glycoprotein 6, putative 0.0027 0.0229 0.0644
Loa Loa (eye worm) ABC transporter 0.0027 0.0229 0.0205
Echinococcus granulosus multidrug resistance protein 1 0.0059 0.0635 0.0635
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Loa Loa (eye worm) cytochrome P450 family protein 0.0011 0.0041 0.0016
Echinococcus granulosus acetylcholinesterase 0.081 1 1
Echinococcus multilocularis acetylcholinesterase 0.081 1 1
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.1605 0.1605
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0085 0.0953 0.2713
Mycobacterium ulcerans hypothetical protein 0.0182 0.2166 1
Brugia malayi Carboxylesterase family protein 0.0137 0.1605 0.1585
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0229 0.0644
Loa Loa (eye worm) hypothetical protein 0.0079 0.0888 0.0865
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0345 0.4204 1
Schistosoma mansoni cpg binding protein 0.0035 0.0331 0.0331
Mycobacterium ulcerans carboxylesterase, LipT 0.0137 0.1605 0.736
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0035 0.0337 0.1004
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0093 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0229 0.0229
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0093 0.0124
Entamoeba histolytica hypothetical protein 0.0027 0.0229 0.0644
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0456 0.4572
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.005 0.0524 0.0501
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0232 0.0458
Brugia malayi ImpB/MucB/SamB family protein 0.005 0.0524 0.0502
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0181 0.0158
Schistosoma mansoni gliotactin 0.0137 0.1605 0.1605
Echinococcus multilocularis dna polymerase eta 0.0079 0.0888 0.0888
Loa Loa (eye worm) hypothetical protein 0.0029 0.0259 0.0235
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0093 0.0124
Plasmodium falciparum multidrug resistance-associated protein 1 0.0027 0.0229 0.0599
Echinococcus multilocularis ATP binding cassette sub family G 0.0012 0.0051 0.0051
Echinococcus granulosus bloom syndrome protein 0.0023 0.0181 0.0181
Toxoplasma gondii ABC transporter, putative 0.0027 0.0229 0.2102
Giardia lamblia DNA damage repair protein 0.0016 0.0093 0.105
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0229 0.0644
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0442 0.0418
Plasmodium vivax arginase, putative 0.0251 0.3027 1
Trichomonas vaginalis aldehyde oxidase, putative 0.0158 0.1869 0.5932
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0365 0.0777
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0664 0.1496
Echinococcus multilocularis dna polymerase kappa 0.0061 0.0664 0.0664
Loa Loa (eye worm) hypothetical protein 0.081 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0026 0.0216 0.0216
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0085 0.0953 0.2713
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0664 0.1496
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Brugia malayi Cytochrome P450 family protein 0.0011 0.0041 0.0018
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0664 0.293
Schistosoma mansoni DNA polymerase IV / kappa 0.0016 0.0093 0.0093
Trichomonas vaginalis taga, putative 0.0085 0.0953 0.2713
Echinococcus multilocularis ATP binding cassette sub family B 0.0084 0.094 0.094
Echinococcus granulosus ATP binding cassette sub family B 0.0027 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0345 0.4204 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0012 0.0042 0.006
Loa Loa (eye worm) acetylcholinesterase 1 0.081 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0093 0.0124
Echinococcus granulosus arginase 2 mitochondrial 0.0251 0.3027 0.3027
Schistosoma mansoni cpg binding protein 0.0035 0.0331 0.0331
Loa Loa (eye worm) latrophilin receptor protein 2 0.0013 0.0065 0.004
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0085 0.0953 0.5
Echinococcus multilocularis BC026374 protein (S09 family) 0.0137 0.1605 0.1605
Trypanosoma cruzi multidrug resistance protein E, putative 0.0027 0.0229 0.0452
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0205
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Plasmodium falciparum ABC transporter B family member 6, putative 0.0027 0.0229 0.0599
Mycobacterium ulcerans hypothetical protein 0.0016 0.0093 0.0242
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0137 0.1605 0.1605
Echinococcus granulosus microtubule associated protein 2 0.0789 0.9736 0.9736
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0345 0.4204 1
Onchocerca volvulus 0.0137 0.1605 1
Echinococcus granulosus carboxylesterase 5A 0.081 1 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0023 0.0181 0.0181
Plasmodium falciparum ABC transporter B family member 4, putative 0.0027 0.0229 0.0599
Echinococcus granulosus 3'partial|arginase 2 mitochondrial 0.0251 0.3027 0.3027
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0035 0.0336 0.9906
Mycobacterium tuberculosis Conserved hypothetical protein 0.0182 0.2166 1
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0023 0.0181 0.0181
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0023 0.0181 0.0156
Trypanosoma brucei ATP-binding cassette protein, putative 0.0012 0.0051 0.0024
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0012 0.0051 0.0024
Trypanosoma brucei multidrug resistance protein E 0.0027 0.0229 0.0452
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0027 0.0229 0.0452
Leishmania major DNA polymerase kappa, putative 0.0016 0.0093 0.0124
Plasmodium falciparum multidrug resistance-associated protein 2 0.0027 0.0229 0.0599
Loa Loa (eye worm) RecQ helicase 0.0023 0.0181 0.0156
Entamoeba histolytica ABC transporter, putative 0.0012 0.0051 0.0048
Loa Loa (eye worm) ABC transporter 0.0011 0.003 0.0005
Trypanosoma brucei p-glycoprotein 0.0027 0.0229 0.0452
Schistosoma mansoni multidrug resistance protein 0.0027 0.0229 0.0229
Trichomonas vaginalis abcb9, putative 0.0085 0.0953 0.2713
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.003 0.0275 0.1201
Mycobacterium ulcerans hypothetical protein 0.0026 0.0219 0.0835
Schistosoma mansoni aldehyde dehydrogenase 0.0044 0.0446 0.0446
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0181 0.0158
Loa Loa (eye worm) hypothetical protein 0.081 1 1
Entamoeba histolytica P-glyco protein 6, putative 0.0085 0.0953 0.3064
Loa Loa (eye worm) hypothetical protein 0.0085 0.0953 0.093
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0023 0.0181 0.0181
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Schistosoma mansoni microtubule-associated protein tau 0.0789 0.9736 0.9736
Plasmodium vivax ABC transporter B family member 3, putative 0.0027 0.0229 0.0644
Onchocerca volvulus 0.0085 0.0953 0.4975
Loa Loa (eye worm) inositol-1 0.0035 0.0337 0.0313
Loa Loa (eye worm) CYP4Cod1 0.0011 0.0041 0.0016
Loa Loa (eye worm) hypothetical protein 0.0085 0.0953 0.093
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0291 0.1278
Schistosoma mansoni hypothetical protein 0.0013 0.0065 0.0065
Loa Loa (eye worm) carboxylesterase 0.0137 0.1605 0.1584
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0012 0.0051 0.0051
Leishmania major p-glycoprotein e 0.0027 0.0229 0.0452
Giardia lamblia MRP-like ABC transporter 0.0027 0.0229 0.3676
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0027 0.0229 0.0171
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0027 0.0229 0.0452
Brugia malayi ABC transporter 0.0027 0.0229 0.0207
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Trypanosoma brucei unspecified product 0.0035 0.033 0.0694
Echinococcus multilocularis dnaJ subfamily B 0.0468 0.5729 0.5729
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0275 0.1098
Leishmania major arginase 0.0251 0.3027 0.7174
Schistosoma mansoni aldehyde dehydrogenase 0.0044 0.0446 0.0446
Plasmodium falciparum ABC transporter B family member 3, putative 0.0027 0.0229 0.0599
Leishmania major DNA polymerase eta, putative 0.0045 0.0456 0.0996
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0168 0.1988 0.1968
Echinococcus multilocularis para nitrobenzyl esterase 0.0137 0.1605 0.1605
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0232 0.0458
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0035 0.0336 0.0336
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.1605 0.1605
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Echinococcus granulosus multidrug resistance associated protein 7 0.0027 0.0229 0.0229
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0085 0.0953 0.0953
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0013 0.0065 0.0065
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0336 0.0958
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0012 0.0051 0.0024
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0504 0.1111
Schistosoma mansoni acetylcholinesterase 0.0137 0.1605 0.1605
Echinococcus multilocularis arginase 2, mitochondrial 0.0251 0.3027 0.3027
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0012 0.0051 0.0024
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.1605 0.7391
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Giardia lamblia Hypothetical protein 0.0026 0.0216 0.3424
Echinococcus granulosus dna polymerase kappa 0.0061 0.0664 0.0664
Entamoeba histolytica P-glycoprotein 5, putative 0.0085 0.0953 0.3064
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0061 0.0664 0.1697
Brugia malayi Cytochrome P450 family protein 0.0011 0.0041 0.0018
Schistosoma mansoni BC026374 protein (S09 family) 0.0137 0.1605 0.1605
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0044 0.0446 0.0446
Brugia malayi ABC transporter family protein 0.0027 0.0229 0.0207
Treponema pallidum hypothetical protein 0.0026 0.0219 0.6004
Echinococcus multilocularis ATP binding cassette sub family G 0.0012 0.0051 0.0051
Trichomonas vaginalis DNA polymerase eta, putative 0.0061 0.0664 0.1697
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0229 0.0644
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0053 0.0564 0.2459
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0767 0.0767
Trichomonas vaginalis abcb9, putative 0.0085 0.0953 0.2713
Brugia malayi latrophilin 2 splice variant baaae 0.0029 0.0259 0.0236
Entamoeba histolytica multidrug resistance protein, putative 0.0027 0.0229 0.0644
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Trypanosoma cruzi DNA polymerase eta, putative 0.0079 0.0888 0.2033
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0137 0.1605 0.1605
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0442 0.0442
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0059 0.0636 0.1429
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0013 0.0065 0.0065
Echinococcus multilocularis 0.0027 0.0229 0.0229
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Echinococcus multilocularis multidrug resistance protein 1 0.0085 0.0953 0.0953
Brugia malayi CXXC zinc finger family protein 0.0033 0.0308 0.0285
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0085 0.0953 0.2713
Echinococcus granulosus dna polymerase eta 0.0079 0.0888 0.0888
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0205
Loa Loa (eye worm) hypothetical protein 0.0027 0.0229 0.0205
Schistosoma mansoni multidrug resistance protein 0.0085 0.0953 0.0953
Schistosoma mansoni multidrug resistance protein 0.0085 0.0953 0.0953
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0035 0.0337 0.3277
Entamoeba histolytica Arginase, putative 0.0251 0.3027 1
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0027 0.0229 0.0452
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0446 0.1906
Plasmodium vivax multidrug resistance protein 2, putative 0.0027 0.0229 0.0644
Trichomonas vaginalis ABC transporter, putative 0.0085 0.0953 0.2713
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0085 0.0953 0.2713
Schistosoma mansoni neuroligin 3 (S09 family) 0.0137 0.1605 0.1605
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0027 0.0229 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0365 0.0777
Entamoeba histolytica P-glycoprotein 6, putative 0.0027 0.0229 0.0644
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0181 0.0158
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0051 0.0046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0446 0.1906
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0027 0.0229 0.0452
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0035 0.0336 0.0708
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0158 0.1869 0.5932
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0053 0.0564 0.2459
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0075 0.0828 0.3701
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0027 0.0229 0.0207
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0026 0.0216 0.0216
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0181 0.0335
Brugia malayi ABC transporter transmembrane region family protein 0.0027 0.0229 0.0207
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0035 0.0336 0.1388
Loa Loa (eye worm) carboxylesterase 0.081 1 1
Echinococcus granulosus inositol monophosphatase 1 0.0035 0.0337 0.0337
Toxoplasma gondii aldehyde dehydrogenase 0.0044 0.0446 0.4467
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0016 0.0093 0.0609
Schistosoma mansoni hypothetical protein 0.0013 0.0065 0.0065
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0053 0.0559 0.1244
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0051 0.0024
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0085 0.0953 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0035 0.0337 0.1392
Echinococcus multilocularis ATP binding cassette sub family B 0.0027 0.0229 0.0229
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0035 0.0336 0.0708
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0025 0.0025
Loa Loa (eye worm) ABC transporter 0.0027 0.0229 0.0205
Entamoeba histolytica P-glycoprotein 5, putative 0.0026 0.0216 0.06
Brugia malayi ImpB/MucB/SamB family protein 0.0079 0.0888 0.0866
Toxoplasma gondii hypothetical protein 0.0056 0.0593 0.6067
Treponema pallidum hypothetical protein 0.0021 0.0162 0.408
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0337 0.0549
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0023 0.0181 0.0181
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0013 0.0065 0.0065
Echinococcus granulosus geminin 0.0194 0.2314 0.2314
Brugia malayi Latrophilin receptor protein 2 0.0013 0.0065 0.0042
Leishmania major pentamidine resistance protein 1 0.0027 0.0229 0.0452
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0027 0.0229 0.0886
Trypanosoma brucei ABC transporter, putative 0.0012 0.0051 0.0024
Echinococcus multilocularis multidrug resistance associated protein 1 0.0027 0.0229 0.0229
Schistosoma mansoni DNA helicase recq5 0.0023 0.0181 0.0181
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0042 0.0426 0.0404
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0027 0.0229 0.0452
Brugia malayi Carboxylesterase family protein 0.0137 0.1605 0.1585
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0181 0.1572
Schistosoma mansoni hypothetical protein 0.0009 0.0016 0.0016
Schistosoma mansoni smdr1 0.0027 0.0229 0.0229
Leishmania major DNA damage repair protein, putative 0.0016 0.0093 0.0124
Trypanosoma brucei DNA polymerase eta, putative 0.0079 0.0888 0.2033
Entamoeba histolytica P-glycoprotein-5 0.0085 0.0953 0.3064
Loa Loa (eye worm) multidrug resistance protein 3 0.0085 0.0953 0.093
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0035 0.0336 0.0708
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0075 0.0828 0.3773
Schistosoma mansoni hypothetical protein 0.0194 0.2314 0.2314
Loa Loa (eye worm) hypothetical protein 0.0026 0.0216 0.0192
Schistosoma mansoni terminal deoxycytidyl transferase 0.005 0.0524 0.0524
Trypanosoma cruzi agmatinase, putative 0.0091 0.1037 0.2392
Echinococcus granulosus multidrug resistance associated protein 1 0.0027 0.0229 0.0229
Plasmodium vivax ABC transporter B family member 5, putative 0.0027 0.0229 0.0644
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0035 0.0336 0.1487
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0337 0.0711
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Brugia malayi ABC transporter family protein 0.0027 0.0229 0.0207
Entamoeba histolytica P-glycoprotein-2, putative 0.0026 0.0216 0.06
Loa Loa (eye worm) hypothetical protein 0.0026 0.0216 0.0192
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0027 0.0229 0.0644
Brugia malayi ABC transporter transmembrane region family protein 0.0027 0.0229 0.0207
Leishmania major mitochondrial DNA polymerase beta 0.0345 0.4204 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0291 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0085 0.0953 0.0953
Echinococcus granulosus ATP binding cassette sub family G 0.0012 0.0051 0.0051
Echinococcus granulosus multidrug resistance protein 1 0.0059 0.0635 0.0635
Entamoeba histolytica ABC transporter, putative 0.0027 0.0229 0.0644
Trypanosoma brucei unspecified product 0.0059 0.0629 0.1413
Schistosoma mansoni ap endonuclease 0.0035 0.0336 0.0336
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0674 0.6953
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0559 0.1244
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0085 0.0953 0.0953
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Trichomonas vaginalis ABC transporter, putative 0.0085 0.0953 0.2713
Echinococcus granulosus ATP binding cassette sub family B 0.0027 0.0229 0.0229
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Treponema pallidum quinoline 2-oxidoreductase 0.0025 0.0211 0.5751
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0084 0.094 0.094
Schistosoma mansoni hypothetical protein 0.0013 0.0065 0.0065
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0456 0.0996
Schistosoma mansoni blooms syndrome DNA helicase 0.0011 0.0037 0.0037
Onchocerca volvulus 0.0137 0.1605 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0085 0.0953 0.0953
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0035 0.0337 1
Echinococcus multilocularis microtubule associated protein 2 0.0789 0.9736 0.9736
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0093 0.0124
Schistosoma mansoni hypothetical protein 0.0013 0.0065 0.0065
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.081 1 1
Giardia lamblia DINP protein human, muc B family 0.0053 0.0559 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0027 0.0229 0.0886
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0035 0.0336 0.1001
Plasmodium falciparum multidrug resistance protein 2 0.0027 0.0229 0.0599
Schistosoma mansoni smdr2 0.0085 0.0953 0.0953
Plasmodium vivax ABC transporter B family member 4, putative 0.0027 0.0229 0.0644
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0085 0.0953 0.0953
Trichomonas vaginalis conserved hypothetical protein 0.0251 0.3027 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0232 0.0208
Loa Loa (eye worm) cytochrome P450 family protein 0.0011 0.0041 0.0016
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0027 0.0229 0.0452
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0504 0.1111
Schistosoma mansoni hypothetical protein 0.0194 0.2314 0.2314
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0085 0.0953 0.0953
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0085 0.0953 0.2191
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0027 0.0229 0.0452
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.005 0.0524 0.0524
Echinococcus granulosus para nitrobenzyl esterase 0.0137 0.1605 0.1605
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.005 0.0524 0.0524
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0027 0.0229 0.0452
Leishmania major DNA polymerase eta, putative 0.0079 0.0888 0.2033
Plasmodium vivax ABC transporter B family member 7, putative 0.0027 0.0229 0.0644
Loa Loa (eye worm) hypothetical protein 0.0023 0.0181 0.0156
Brugia malayi ABC transporter family protein 0.0085 0.0953 0.0932
Plasmodium falciparum ABC transporter B family member 5, putative 0.0027 0.0229 0.0599
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0337 0.0711
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0442 0.0442
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0026 0.0216 0.3424
Plasmodium falciparum arginase 0.0251 0.3027 1
Trypanosoma brucei chrX additional, unordered contigs 0.0016 0.0093 0.0124
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0051 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Schistosoma mansoni inositol monophosphatase 0.0035 0.0337 0.0337
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.0504 0.1111
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0013 0.0065 0.0042
Echinococcus multilocularis multidrug resistance protein 1 0.0085 0.0953 0.0953
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0137 0.1605 0.5004
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0027 0.0229 0.0452
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0158 0.1869 0.5932
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Loa Loa (eye worm) carboxylesterase 0.0137 0.1605 0.1584
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0027 0.0229 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0026 0.0216 0.0125
Echinococcus granulosus cpg binding protein 0.0035 0.0331 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0504 0.1111
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0023 0.0181 0.0436
Echinococcus multilocularis 0.0251 0.3027 0.3027
Trypanosoma brucei agmatinase, putative 0.0091 0.1037 0.2392
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0012 0.0051 0.0046
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0075 0.0828 0.3701
Entamoeba histolytica deoxycytidyl transferase, putative 0.005 0.0524 0.163
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0336 0.0545
Toxoplasma gondii ABC transporter family protein 0.0027 0.0229 0.2102
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0042 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0025 0.0025
Mycobacterium tuberculosis Carboxylesterase LipT 0.0137 0.1605 0.7391
Schistosoma mansoni arginase 0.0251 0.3027 0.3027
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0137 0.1605 0.1605
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0275 0.1098
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0047 0.0483 0.2077
Brugia malayi Cytochrome P450 family protein 0.0019 0.0134 0.0111
Brugia malayi ABC transporter 0.0026 0.0216 0.0193
Trichomonas vaginalis ABC transporter, putative 0.0085 0.0953 0.2713
Loa Loa (eye worm) hypothetical protein 0.0012 0.0042 0.0017
Echinococcus multilocularis multidrug resistance protein 1 0.0059 0.0635 0.0635
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0044 0.0446 0.1999
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0053 0.0564 0.2546
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0027 0.0229 0.0886
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0027 0.0229 0.0452
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0336 0.1001
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0216 0.0125
Entamoeba histolytica ATP-binding cassette protein, putative 0.0027 0.0229 0.0644
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0027 0.0229 0.0452
Entamoeba histolytica recQ family DNA helicase 0.0012 0.0042 0.0018
Plasmodium vivax DNA repair protein REV1, putative 0.0016 0.0093 0.0187
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0442 0.0442
Toxoplasma gondii exonuclease III APE 0.0035 0.0336 0.3266
Schistosoma mansoni ABC transporter 0.0011 0.003 0.003
Trichomonas vaginalis spcc417.12 protein, putative 0.0137 0.1605 0.5004
Schistosoma mansoni multidrug resistance protein 0.0027 0.0229 0.0229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0442 0.0442
Brugia malayi MH2 domain containing protein 0.0114 0.1317 0.1296
Trichomonas vaginalis ABC transporter, putative 0.0085 0.0953 0.2713
Schistosoma mansoni hypothetical protein 0.0029 0.0259 0.0259
Brugia malayi multidrug resistance protein 3 0.0085 0.0953 0.0932
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0085 0.0953 0.2713
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0027 0.0229 0.0886
Echinococcus multilocularis cpg binding protein 0.0035 0.0331 0.0331
Echinococcus multilocularis neuroligin 0.0137 0.1605 0.1605
Schistosoma mansoni multidrug resistance protein 0.0027 0.0229 0.0229
Echinococcus granulosus acetylcholinesterase 0.081 1 1
Onchocerca volvulus 0.0137 0.1605 1
Loa Loa (eye worm) transcription factor SMAD2 0.0114 0.1317 0.1295
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0105 0.1204 0.5472
Trypanosoma cruzi agmatinase, putative 0.0091 0.1037 0.2392
Plasmodium vivax ABC transporter B family member 6, putative 0.0027 0.0229 0.0644
Loa Loa (eye worm) MH2 domain-containing protein 0.0114 0.1317 0.1295
Plasmodium falciparum multidrug resistance protein 1 0.0085 0.0953 0.3031
Schistosoma mansoni DNA polymerase eta 0.0079 0.0888 0.0888
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0137 0.1605 0.7391
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0365 0.0777
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0012 0.0051 0.0155
Leishmania major DNA polymerase kappa, putative 0.0053 0.0559 0.1244
Brugia malayi hypothetical protein 0.0027 0.0229 0.0207
Plasmodium falciparum ABC transporter B family member 7, putative 0.0027 0.0229 0.0599
Brugia malayi exodeoxyribonuclease III family protein 0.0035 0.0336 0.0313
Echinococcus granulosus GPCR family 2 0.0013 0.0065 0.0065
Plasmodium falciparum DNA repair protein REV1, putative 0.0016 0.0093 0.014
Schistosoma mansoni ap endonuclease 0.0035 0.0336 0.0336
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0027 0.0229 0.0991
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0085 0.0953 0.4357
Giardia lamblia Multidrug resistance-associated protein 1 0.0027 0.0229 0.3676
Echinococcus granulosus multidrug resistance protein 1 0.0085 0.0953 0.0953
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0035 0.0336 0.0708
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0035 0.0336 0.5722
Schistosoma mansoni blooms syndrome DNA helicase 0.0012 0.0042 0.0042
Giardia lamblia Multidrug resistance-associated protein 1 0.0027 0.0229 0.3676
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0085 0.0953 0.0953
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0181 0.0335
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0085 0.0953 0.2713
Schistosoma mansoni multidrug resistance protein 0.0026 0.0216 0.0216
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0442 0.0419
Echinococcus multilocularis inositol monophosphatase 1 0.0035 0.0337 0.0337
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0044 0.0446 0.0973
Trypanosoma cruzi arginase, putative 0.0091 0.1037 0.2392
Entamoeba histolytica P-glycoprotein-2 0.0085 0.0953 0.3064
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0181 0.0335
Treponema pallidum exodeoxyribonuclease (exoA) 0.0035 0.0336 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0442 0.0442
Plasmodium vivax multidrug resistance protein 1, putative 0.0085 0.0953 0.3064
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0012 0.0042 0.0018
Trypanosoma brucei DNA damage repair protein, putative 0.0016 0.0093 0.0124
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0337 0.0549
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Giardia lamblia Multidrug resistance-associated protein 1 0.0026 0.0216 0.3424
Brugia malayi follicle stimulating hormone receptor 0.0168 0.1988 0.1969
Trypanosoma brucei unspecified product 0.0035 0.033 0.0694
Loa Loa (eye worm) hypothetical protein 0.0012 0.0042 0.0017
Echinococcus multilocularis ATP binding cassette sub family G 0.0012 0.0051 0.0051
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0027 0.0229 0.0886
Schistosoma mansoni multidrug resistance protein 0.0027 0.0229 0.0229
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0042 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0337 0.0711
Echinococcus granulosus multidrug resistance protein 1 0.0085 0.0953 0.0953
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0163 0.1936 0.4552
Schistosoma mansoni multidrug resistance protein 0.0027 0.0229 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Brugia malayi ABC transporter family protein 0.0027 0.0229 0.0207
Brugia malayi Carboxylesterase family protein 0.0137 0.1605 0.1585
Schistosoma mansoni hypothetical protein 0.0468 0.5729 0.5729
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0027 0.0229 0.0229
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0053 0.0559 0.2524
Onchocerca volvulus 0.0137 0.1605 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0013 0.0065 0.0065
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0027 0.0229 0.0644
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0026 0.0216 0.0125
Brugia malayi ABC transporter family protein 0.0011 0.003 0.0006
Schistosoma mansoni inositol monophosphatase 0.0035 0.0337 0.0337
Leishmania major ABC-thiol transporter 0.0027 0.0229 0.0452
Brugia malayi ABC transporter transmembrane region family protein 0.0026 0.0216 0.0193
Echinococcus granulosus ATP binding cassette sub family G 0.0012 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584
Entamoeba histolytica P-glycoprotein-2, putative 0.0085 0.0953 0.3064
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0044 0.0446 0.0446
Echinococcus multilocularis geminin 0.0194 0.2314 0.2314
Brugia malayi Inositol-1 0.0035 0.0337 0.0314
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0181 0.0181
Onchocerca volvulus 0.0137 0.1605 1
Schistosoma mansoni cpg binding protein 0.0033 0.0308 0.0308
Echinococcus granulosus BC026374 protein S09 family 0.0137 0.1605 0.1605
Brugia malayi P-glycoprotein-like protein 0.0027 0.0229 0.0207
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0027 0.0229 0.2102
Trichomonas vaginalis inositol monophosphatase, putative 0.0035 0.0337 0.0549
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0442 0.0442
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0085 0.0953 0.093
Schistosoma mansoni multidrug resistance protein 0.0085 0.0953 0.0953
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Leishmania major p-glycoprotein 0.0085 0.0953 0.2191
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0085 0.0953 1
Brugia malayi Carboxylesterase family protein 0.081 1 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0337 0.0711
Plasmodium vivax ABC transporter G family member 2, putative 0.0012 0.0051 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0664 0.1496
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0664 0.293
Entamoeba histolytica P-glycoprotein-2 0.0085 0.0953 0.3064
Loa Loa (eye worm) hypothetical protein 0.0084 0.094 0.0917
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0035 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0042 0.0426 0.0402
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0181 0.1572
Brugia malayi Calcitonin receptor-like protein seb-1 0.0042 0.0426 0.0404
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0163 0.1936 0.4552
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0042 0.0426 0.0402
Trichomonas vaginalis abcb9, putative 0.0085 0.0953 0.2713
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0026 0.0216 0.0125
Trypanosoma cruzi DNA damage repair protein, putative 0.0016 0.0093 0.0124
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0085 0.0953 0.2713
Echinococcus multilocularis acetylcholinesterase 0.081 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0085 0.0953 0.0953
Brugia malayi hypothetical protein 0.0137 0.1605 0.1585
Mycobacterium tuberculosis Conserved hypothetical protein 0.005 0.0524 0.2363
Entamoeba histolytica P-glycoprotein-1 0.0085 0.0953 0.3064
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0027 0.0229 0.0452
Echinococcus multilocularis carboxylesterase 5A 0.081 1 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.005 0.0524 0.0524
Giardia lamblia Sgs1 DNA helicase, putative 0.0023 0.0181 0.2743
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0085 0.0953 0.2713
Loa Loa (eye worm) ABC transporter 0.0027 0.0229 0.0205
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0027 0.0229 0.0452
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0085 0.0953 0.2713
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0027 0.0229 0.2102
Echinococcus multilocularis GPCR, family 2 0.0013 0.0065 0.0065
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0085 0.0953 0.0953
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0163 0.1936 0.4552
Giardia lamblia ABC transporter, putative 0.0027 0.0229 0.3676
Loa Loa (eye worm) hypothetical protein 0.0137 0.1605 0.1584

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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