Detailed information for compound 2073769

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 461.513 | Formula: C25H27N5O4
  • H donors: 1 H acceptors: 3 LogP: 1.86 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)N1N=C(C2C1C(=O)N(CC2)c1ccc(cc1)N1CCCCC1=O)C(=O)N
  • InChi: 1S/C25H27N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12,20,23H,2-4,13-15H2,1H3,(H2,26,32)
  • InChiKey: HPROUOWNFHBVDH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni jumonji/arid domain-containing protein 0.0027 0.04 0.0253
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0264 0.0115
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0018 0.02 0.0049
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0032 0.05 0.3352
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0264 0.0263
Echinococcus granulosus voltage gated hydrogen channel 1 0.0018 0.02 0.0198
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.02 0.0198
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.02 0.0198
Onchocerca volvulus 0.0022 0.028 0.0787
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.02 0.0556
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0018 0.02 0.1311
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0018 0.02 0.0198
Schistosoma mansoni alpha(13)fucosyltransferase 0.021 0.4358 0.4272
Brugia malayi cation channel family protein 0.0018 0.02 0.0207
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Toxoplasma gondii hypothetical protein 0.0018 0.02 0.1311
Echinococcus multilocularis purine nucleoside phosphorylase 0.0116 0.2316 0.2314
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0229 0.0227
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0229 0.0227
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0041 0.0698 0.0743
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0263 0.1743
Brugia malayi alpha1,3-fucosyltransferase homologue 0.021 0.4358 0.4676
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Loa Loa (eye worm) voltage-gated calcium channel 0.0018 0.02 0.0207
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0069 0.1301 0.1299
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0192 0.1258
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Toxoplasma gondii phosphorylase family protein 0.003 0.0462 0.3094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Schistosoma mansoni hypothetical protein 0.0471 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0028 0.0405 0.0403
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.02 0.0049
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0077 0.1479 1
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.003 0.0462 0.0683
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.02 0.0207
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0018 0.02 0.0198
Brugia malayi cation channel family protein 0.0018 0.02 0.0207
Echinococcus granulosus sodium leak channel non selective protein 0.0018 0.02 0.0198
Echinococcus granulosus potassium large conductance calcium activated 0.0018 0.02 0.0198
Plasmodium vivax SET domain protein, putative 0.0022 0.028 0.6046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Echinococcus multilocularis potassium large conductance calcium activated 0.0018 0.02 0.0198
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0229 0.0227
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Echinococcus multilocularis conserved hypothetical protein 0.0018 0.02 0.0198
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0018 0.02 0.0198
Schistosoma mansoni hypothetical protein 0.013 0.2621 0.2508
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0018 0.02 0.0049
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0146 0.2971 0.4445
Schistosoma mansoni uridine phosphorylase 0.003 0.0462 0.0316
Schistosoma mansoni cpg binding protein 0.0033 0.0523 0.0378
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.02 0.0049
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Echinococcus granulosus Transcription initiation factor TFIID subunit 0.0054 0.0972 0.0971
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0021 0.0263 0.0276
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.02 0.0198
Plasmodium falciparum phd finger protein, putative 0.0021 0.0263 0.5697
Brugia malayi Transient-receptor-potential like protein 0.0018 0.02 0.0207
Leishmania major eukaryotic translation initiation factor-like protein 0.0077 0.1479 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0698 0.0696
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0018 0.02 0.0198
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0077 0.1479 0.1478
Toxoplasma gondii phosphorylase family protein 0.003 0.0462 0.3094
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Brugia malayi translation initiation factor 4E 0.0077 0.1479 0.1583
Entamoeba histolytica hypothetical protein 0.0028 0.0405 0.0597
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Schistosoma mansoni vesicular amine transporter 0.0018 0.02 0.0049
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0192 0.5
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.003 0.0462 0.091
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Echinococcus granulosus two pore calcium channel protein 1 0.0018 0.02 0.0198
Leishmania major glycosyl transferase, putative 0.0035 0.0574 0.3853
Echinococcus granulosus shaker cognate 0.0018 0.02 0.0198
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.0263 0.0114
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.0263 0.0262
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Schistosoma mansoni hypothetical protein 0.0021 0.0263 0.0114
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Loa Loa (eye worm) hypothetical protein 0.0089 0.1739 0.1862
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.1583
Echinococcus multilocularis shaker cognate 0.0018 0.02 0.0198
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.02 0.0198
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0146 0.2971 0.9356
Schistosoma mansoni alpha 13/4 fucosyltransferase Lewis 1 0.0121 0.2426 0.231
Brugia malayi jmjC domain containing protein 0.0027 0.04 0.0423
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0264 0.0115
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0018 0.02 0.0207
Echinococcus granulosus lysine specific demethylase 5A 0.0027 0.04 0.0398
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.02 0.0198
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.02 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0462 0.049
Schistosoma mansoni hypothetical protein 0.0018 0.02 0.0049
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0264 0.0263
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.003 0.0462 0.049
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0264 0.0277
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0523 0.0555
Loa Loa (eye worm) glutaminase 0.0439 0.9312 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0018 0.02 0.0198
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0077 0.1479 1
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.02 0.0198
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0032 0.05 0.3352
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0032 0.05 0.0499
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.003 0.0462 0.0683
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0146 0.2971 0.3185
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0264 0.0263
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0018 0.02 0.1311
Leishmania major hypothetical protein, conserved 0.0018 0.02 0.1311
Entamoeba histolytica DNA repair and recombination protein, putative 0.0032 0.05 0.074
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0146 0.2971 0.3185
Trypanosoma cruzi nucleoside phosphorylase, putative 0.003 0.0462 0.3094
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.003 0.0462 0.3094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Schistosoma mansoni glutaminase 0.0439 0.9312 0.9301
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0317 0.6674 1
Echinococcus granulosus eukaryotic translation initiation factor 4E type 0.0009 0.0007 0.0005
Giardia lamblia UPL-1 0.003 0.0462 0.0683
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.02 0.0198
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0229 0.0227
Brugia malayi hypothetical protein 0.0028 0.0405 0.0428
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.02 0.0198
Echinococcus multilocularis transfer RNA-Gly 0.0018 0.02 0.0198
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0007 0.0144
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0146 0.2971 0.8544
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.02 0.0198
Echinococcus multilocularis transient receptor potential gamma protein 0.0018 0.02 0.0198
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.1342 0.1209
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0264 0.0115
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.002 0.0247 0.0245
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0032 0.05 0.3352
Echinococcus multilocularis purine nucleoside phosphorylase 0.0116 0.2316 0.2314
Echinococcus granulosus hypothetical protein 0.0018 0.02 0.0198
Schistosoma mansoni purine nucleoside phosphorylase 0.0146 0.2971 0.2863
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0264 0.0263
Onchocerca volvulus Alhambra homolog 0.0021 0.0263 0.074
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.003 0.0462 0.3094
Giardia lamblia Fructose-bisphosphate aldolase 0.0317 0.6674 1
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.05 0.0531
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0018 0.02 0.0207
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0229 0.0227
Leishmania major eukaryotic translation initiation factor-like 0.0077 0.1479 1
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.02 0.1311
Onchocerca volvulus 0.0018 0.02 0.0556
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0264 0.0263
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Entamoeba histolytica hypothetical protein 0.0028 0.0405 0.0597
Echinococcus granulosus transient receptor potential cation channel 0.0018 0.02 0.0198
Schistosoma mansoni alpha(13)fucosyltransferase 0.021 0.4358 0.4272
Echinococcus multilocularis methylthioadenosine phosphorylase 0.003 0.0462 0.0461
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0018 0.02 0.0198
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.028 0.0131
Brugia malayi jmjC domain containing protein 0.0069 0.1301 0.1391
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0018 0.02 0.0207
Schistosoma mansoni methylthioadenosine phosphorylase 0.003 0.0462 0.0316
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0018 0.02 0.0207
Loa Loa (eye worm) uridine phosphorylase 0.003 0.0462 0.049
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.3162 1
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.02 0.0198
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0263 0.1743
Trypanosoma cruzi nucleoside phosphorylase, putative 0.003 0.0462 0.3094
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0192 0.4153
Loa Loa (eye worm) hypothetical protein 0.0021 0.0264 0.0277
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0264 0.0263
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.02 0.1311
Giardia lamblia PHD finger protein 15 0.0021 0.0263 0.0385
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0018 0.02 0.0049
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0018 0.02 0.0049
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0018 0.02 0.0198
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.04 0.0423
Plasmodium vivax purine nucleoside phosphorylase, putative 0.003 0.0462 1
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Schistosoma mansoni hypothetical protein 0.0032 0.05 0.0355
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0041 0.0698 0.0743
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Echinococcus multilocularis voltage dependent calcium channel 0.0018 0.02 0.0198
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.028 0.0293
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0146 0.2971 0.9292
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.0359 0.0358
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0146 0.2971 0.3047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0698 0.0696
Echinococcus multilocularis ryanodine receptor 44f 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0018 0.02 0.0049
Loa Loa (eye worm) hypothetical protein 0.0054 0.0972 0.1038
Brugia malayi voltage-dependent calcium channel 0.0018 0.02 0.0207
Schistosoma mansoni transient receptor potential channel 0.0019 0.0229 0.008
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0018 0.02 0.0049
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0018 0.02 0.0556
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0018 0.02 0.0207
Loa Loa (eye worm) translation initiation factor 4E 0.0077 0.1479 0.1583
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0116 0.2316 0.2481
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0022 0.028 0.0131
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0077 0.1479 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0264 0.0115
Echinococcus granulosus histone lysine methyltransferase setb 0.0022 0.028 0.0278
Echinococcus granulosus transient receptor potential gamma protein 0.0018 0.02 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0574 0.3853
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.02 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0574 0.3853
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.02 0.0207
Schistosoma mansoni methylthioadenosine phosphorylase 0.003 0.0462 0.0316
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0138 0.2805 0.8067
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0022 0.028 0.0278
Echinococcus multilocularis sodium leak channel non selective protein 0.0018 0.02 0.0198
Echinococcus multilocularis two pore calcium channel protein 2 0.0018 0.02 0.0198
Leishmania major methylthioadenosine phosphorylase, putative 0.003 0.0462 0.3094
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0032 0.05 0.3352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0698 0.0555
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0028 0.0405 0.0403
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0192 0.0199
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0698 0.0696
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0264 0.0263
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0192 0.019
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.003 0.0462 0.0683
Echinococcus multilocularis two pore calcium channel protein 1 0.0018 0.02 0.0198
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.003 0.0462 0.0683
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0018 0.02 0.0207
Brugia malayi Bromodomain containing protein 0.0021 0.0263 0.0276
Schistosoma mansoni alpha(13)fucosyltransferase 0.021 0.4358 0.4272
Brugia malayi N-terminal motif family protein 0.0138 0.2805 0.3008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.02 0.1311
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.02 0.0198
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0263 0.5697
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0018 0.02 0.1311
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0032 0.05 0.0499
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0018 0.02 0.0198
Echinococcus granulosus uridine phosphorylase 1 0.003 0.0462 0.0461
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0032 0.05 0.3352
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0264 0.0277
Entamoeba histolytica hypothetical protein 0.003 0.0462 0.0683
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.0263 0.0262
Plasmodium falciparum eukaryotic translation initiation factor 4E, putative 0.0009 0.0007 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Brugia malayi glutaminase DH11.1 0.0439 0.9312 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0018 0.02 0.0198
Brugia malayi Fucosyl transferase family protein 0.021 0.4358 0.4676
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0018 0.02 0.1311
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Brugia malayi uridine phosphorylase family protein 0.003 0.0462 0.049
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0192 0.019
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0264 0.0263
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0018 0.02 0.0198
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.2209
Schistosoma mansoni two-pore calcium channel 0.0018 0.02 0.0049
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0192 0.0199
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.02 0.0198
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.05 0.074
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0022 0.028 0.1853
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0018 0.02 0.0207
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.1583
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Leishmania major nucleoside phosphorylase-like protein 0.003 0.0462 0.3094
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus multilocularis cpg binding protein 0.0035 0.0564 0.0562
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0018 0.02 0.1311
Schistosoma mansoni transient receptor potential channel 0.0018 0.02 0.0049
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0264 0.0115
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.003 0.0462 0.0683
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0264 0.0263
Echinococcus granulosus geminin 0.013 0.2621 0.262
Echinococcus multilocularis sodium channel protein 0.0018 0.02 0.0198
Treponema pallidum pfs protein (pfs) 0.003 0.0462 0.0417
Schistosoma mansoni calcium-activated potassium channel 0.0018 0.02 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0046 0.0044
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.003 0.0462 0.0683
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0032 0.05 0.3352
Echinococcus multilocularis transient receptor potential cation channel 0.0018 0.02 0.0198
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.02 0.0049
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0032 0.05 0.3352
Brugia malayi ion channel NompC 0.0018 0.02 0.0207
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0077 0.1479 1
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0046 0.0042
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Loa Loa (eye worm) ion channel NompC 0.0018 0.02 0.0207
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0263 0.0276
Schistosoma mansoni uridine phosphorylase 0.003 0.0462 0.0316
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0018 0.02 0.0198
Schistosoma mansoni ryanodine receptor related 0.0018 0.02 0.0049
Echinococcus multilocularis purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0264 0.0263
Brugia malayi CXXC zinc finger family protein 0.0033 0.0523 0.0555
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.02 0.0198
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0192 0.1258
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0264 0.0263
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0077 0.1479 0.1478
Schistosoma mansoni hypothetical protein 0.0028 0.0405 0.0258
Brugia malayi hypothetical protein 0.0018 0.02 0.0207
Brugia malayi Pre-SET motif family protein 0.0148 0.3006 0.3224
Plasmodium vivax translation initiation factor 4E, putative 0.0009 0.0007 0.0144
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0018 0.02 0.0198
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0192 0.1258
Mycobacterium ulcerans glutaminase 0.0439 0.9312 1
Echinococcus multilocularis jumonji domain containing protein 0.0029 0.0442 0.044
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0077 0.1479 0.1349
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0022 0.028 0.0278
Onchocerca volvulus Alpha 1,3 fucosyltransferase homolog 0.0089 0.1739 0.4994
Brugia malayi PHD-finger family protein 0.0021 0.0263 0.0276
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0264 0.0263
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.2209
Echinococcus multilocularis geminin 0.013 0.2621 0.262
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0018 0.02 0.0207
Schistosoma mansoni purine nucleoside phosphorylase 0.0146 0.2971 0.2863
Echinococcus multilocularis peregrin 0.0021 0.0263 0.0262
Echinococcus granulosus sodium channel protein 0.0018 0.02 0.0198
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0192 0.4153
Echinococcus multilocularis short transient receptor potential channel 6 0.0018 0.02 0.0198
Onchocerca volvulus 0.0169 0.3476 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0192 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0589 0.0626
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0018 0.02 0.0207
Echinococcus granulosus peregrin 0.0021 0.0263 0.0262
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.02 0.0049
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0192 0.0199
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0264 0.0277
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Echinococcus granulosus alpha13fucosyltransferase 0.0089 0.1739 0.1738
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0021 0.0264 0.0277
Loa Loa (eye worm) hypothetical protein 0.0138 0.2805 0.3008
Loa Loa (eye worm) fucosyl transferase 0.021 0.4358 0.4676
Brugia malayi olfactory channel protein osm-9 0.0019 0.0229 0.0239
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0018 0.02 0.0207
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0698 0.0555
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.3162 0.3256
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0148 0.3006 0.3224
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0018 0.02 0.0049
Brugia malayi Pre-SET motif family protein 0.0022 0.028 0.0293
Entamoeba histolytica hypothetical protein 0.0028 0.0405 0.0597
Schistosoma mansoni hypothetical protein 0.006 0.1096 0.096
Toxoplasma gondii transporter, cation channel family protein 0.0018 0.02 0.1311
Echinococcus granulosus glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0021 0.0264 0.0277
Echinococcus granulosus TRP transient receptor potential channel 0.0018 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0077 0.1479 1
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0018 0.02 0.0198
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.003 0.0462 0.0417
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0192 0.1258
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0018 0.02 0.0198
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0116 0.2316 0.2314
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.003 0.0462 0.0683
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.02 0.0049
Loa Loa (eye worm) glutaminase 2 0.0439 0.9312 1
Schistosoma mansoni cpg binding protein 0.0035 0.0564 0.0419
Echinococcus multilocularis uridine phosphorylase 1 0.003 0.0462 0.0461
Toxoplasma gondii hypothetical protein 0.0018 0.02 0.1311
Schistosoma mansoni voltage-gated cation channel 0.0018 0.02 0.0049
Trypanosoma cruzi nucleoside phosphorylase, putative 0.003 0.0462 0.3094
Schistosoma mansoni methylthioadenosine phosphorylase 0.003 0.0462 0.0316
Mycobacterium tuberculosis Conserved hypothetical protein 0.003 0.0462 0.091
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0021 0.0264 0.0263
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.003 0.0462 0.0683
Echinococcus granulosus voltage gated potassium channel 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated ion channel 0.0018 0.02 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.003 0.0462 0.0296
Onchocerca volvulus 0.0033 0.0523 0.1488
Entamoeba histolytica hypothetical protein 0.0028 0.0405 0.0597
Trichomonas vaginalis glutaminase, putative 0.0439 0.9312 1
Echinococcus multilocularis glycoprotein 3 alpha L fucosyltransferase 0.0089 0.1739 0.1738
Chlamydia trachomatis AMP nucleosidase 0.003 0.0462 0.5
Echinococcus granulosus purine nucleoside phosphorylase 0.0146 0.2971 0.2969
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.02 0.0198
Schistosoma mansoni jumonji/arid domain-containing protein 0.0027 0.04 0.0253
Schistosoma mansoni alpha(13)fucosyltransferase 0.021 0.4358 0.4272
Echinococcus granulosus methylthioadenosine phosphorylase 0.003 0.0462 0.0461
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0192 0.0199
Schistosoma mansoni transient receptor potential channel 0.0018 0.02 0.0049
Echinococcus granulosus ryanodine receptor 44f 0.0018 0.02 0.0198
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0089 0.1739 0.1738
Toxoplasma gondii Purine nucleoside phosphorylase 0.003 0.0462 0.3094
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.003 0.0462 0.3094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.6674 0.7165
Loa Loa (eye worm) voltage-dependent calcium channel 0.0018 0.02 0.0207
Loa Loa (eye worm) hypothetical protein 0.021 0.4358 0.4676
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0264 0.0115
Giardia lamblia Rrm3p helicase 0.0032 0.05 0.074
Mycobacterium tuberculosis Hypothetical protein 0.003 0.0462 0.091
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0192 0.0278
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.1583
Echinococcus multilocularis Transcription initiation factor TFIID subunit 0.0054 0.0972 0.0971
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0077 0.1479 0.1583
Toxoplasma gondii exonuclease III APE 0.0018 0.0192 0.1258
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Loa Loa (eye worm) calcium channel 0.0018 0.02 0.0207
Echinococcus granulosus two pore calcium channel protein 2 0.0018 0.02 0.0198
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0264 0.0277
Echinococcus granulosus jumonji domain containing protein 0.0029 0.0442 0.044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.028 0.0131
Echinococcus multilocularis potassium voltage gated channel protein 0.0018 0.02 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0264 0.0115
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.118 0.7967
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0698 0.0696
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus granulosus voltage dependent calcium channel 0.0018 0.02 0.0198
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Trichomonas vaginalis set domain proteins, putative 0.0168 0.3446 0.3696
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0264 0.0115
Loa Loa (eye worm) ryanodine receptor 0.0018 0.02 0.0207
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus granulosus short transient receptor potential channel 6 0.0018 0.02 0.0198
Treponema pallidum fructose-bisphosphate aldolase 0.0317 0.6674 1
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.003 0.0462 0.0296
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0698 0.0555
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0264 0.0263
Trypanosoma brucei uridine phosphorylase 0.003 0.0462 0.3094
Echinococcus multilocularis dnaJ subfamily B 0.0471 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.028 0.0131
Schistosoma mansoni ap endonuclease 0.0018 0.0192 0.0042
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0192 0.0199
Schistosoma mansoni ap endonuclease 0.0018 0.0192 0.0042
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0317 0.6674 1
Leishmania major hypothetical protein, unknown function 0.0018 0.02 0.1311
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0264 0.0115
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.003 0.0462 0.049
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0069 0.1301 0.1299
Loa Loa (eye worm) voltage-gated potassium channel 0.0018 0.02 0.0207
Schistosoma mansoni cpg binding protein 0.0035 0.0564 0.0419
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0264 0.0263
Echinococcus granulosus cpg binding protein 0.0035 0.0564 0.0562
Schistosoma mansoni transient receptor potential channel 4 0.0018 0.02 0.0049
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0264 0.0277
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0021 0.0264 0.0277
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0749 0.0798
Brugia malayi MTAP 0.003 0.0462 0.049
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.3162 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.02 0.0207
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0046 0.0044
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0021 0.0264 0.0277
Schistosoma mansoni transcription factor LCR-F1 0.0028 0.0405 0.0258
Plasmodium falciparum purine nucleoside phosphorylase 0.003 0.0462 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0018 0.02 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0462 0.049
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0018 0.02 0.0207
Schistosoma mansoni alpha(13)fucosyltransferase 0.021 0.4358 0.4272
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0021 0.0264 0.0263
Schistosoma mansoni voltage-dependent calcium channel 0.0018 0.02 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.02 0.0049
Schistosoma mansoni alpha(13)fucosyltransferase 0.0035 0.0574 0.043
Plasmodium falciparum eukaryotic translation initiation factor 4E 0.0009 0.0007 0.0144
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0018 0.02 0.0207
Schistosoma mansoni hypothetical protein 0.013 0.2621 0.2508
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0264 0.0263
Echinococcus multilocularis alpha(13)fucosyltransferase 0.0089 0.1739 0.1738
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0018 0.02 0.1311
Schistosoma mansoni jumonji domain containing protein 0.0055 0.0994 0.0856
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0264 0.0115
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0018 0.02 0.0198
Echinococcus granulosus potassium voltage gated channel protein 0.0018 0.02 0.0198
Echinococcus granulosus calcium activated potassium channel 0.0018 0.02 0.0198
Loa Loa (eye worm) hypothetical protein 0.0019 0.0229 0.0239
Treponema pallidum uridine phosphorylase (udp) 0.003 0.0462 0.0417

Activities

Activity type Activity value Assay description Source Reference
T1/2 (ADMET) = 12 hr Half life in human administered bid orally ChEMBL. 23386703

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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