Detailed information for compound 2074435

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 357.336 | Formula: C18H16FN3O4
  • H donors: 4 H acceptors: 4 LogP: 1.46 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CNC(=O)c1c(C)[nH]c(c1C)/C=C/1\C(=O)Nc2c1cc(F)cc2
  • InChi: 1S/C18H16FN3O4/c1-8-14(21-9(2)16(8)18(26)20-7-15(23)24)6-12-11-5-10(19)3-4-13(11)22-17(12)25/h3-6,21H,7H2,1-2H3,(H,20,26)(H,22,25)(H,23,24)/b12-6-
  • InChiKey: PCPTUYGTADXVFI-SDQBBNPISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax vivapain-2 0.0019 0.0089 0.2767
Onchocerca volvulus 0.0019 0.0089 0.0151
Echinococcus multilocularis lamin 0.003 0.0221 0.0221
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1274 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0252 0.5
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0089 0.0151
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0055 0.0505 0.1019
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0018 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0055 0.0505 0.0849
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0323 0.2538
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1274 1
Brugia malayi prostaglandin transporter 0.0033 0.0249 0.0503
Schistosoma mansoni hypothetical protein 0.0081 0.08 0.1615
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0171 0.0289
Brugia malayi cathepsin L-like precursor 0.0013 0.0018 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0505 0.1019
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.006 0.0121
Onchocerca volvulus Phospholipase A2 homolog 0.0111 0.1152 0.1938
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0171 0.0346
Leishmania major ATP-dependent phosphofructokinase 0.0122 0.1274 1
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0121 0.0244
Echinococcus multilocularis agrin 0.0022 0.013 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Loa Loa (eye worm) phosphofructokinase 0.0122 0.1274 0.2144
Onchocerca volvulus 0.0033 0.0249 0.0419
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0149 0.03
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.2746 1
Brugia malayi nuclear receptor NHR-88 0.0026 0.0171 0.0346
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0221 0.0372
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1274 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0171 0.0289
Brugia malayi photoreceptor-specific nuclear receptor 0.0055 0.0505 0.1019
Echinococcus granulosus cathepsin l1 0.0019 0.0089 0.0181
Loa Loa (eye worm) RecQ helicase 0.0024 0.0149 0.025
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0055 0.0505 0.1019
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0121 0.0244
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0081 0.08 0.08
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0121 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0323 0.2416
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0121 0.0244
Echinococcus granulosus lamin 0.003 0.0221 0.0447
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0171 0.0346
Schistosoma mansoni sodium-bile acid cotransporter 0.0147 0.1565 0.3159
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0121 0.0121
Brugia malayi steroid hormone receptor 0.0055 0.0505 0.1019
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0055 0.0505 0.0849
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Brugia malayi beta-lactamase family protein 0.0039 0.0323 0.0653
Onchocerca volvulus 0.0026 0.0171 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0055 0.0505 0.0849
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0323 0.0653
Schistosoma mansoni follistatin 0.0022 0.013 0.0262
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.007
Brugia malayi PXA domain containing protein 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0121 0.0121
Echinococcus granulosus lamin dm0 0.003 0.0221 0.0447
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0696 0.5385
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0323 0.0544
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0121 0.0244
Loa Loa (eye worm) DR-78 0.0026 0.0171 0.0289
Entamoeba histolytica hypothetical protein 0.0021 0.0121 0.0948
Brugia malayi nuclear hormone receptor 0.0055 0.0505 0.1019
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0323 0.0653
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0252 0.7795
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0121 0.0244
Onchocerca volvulus 0.0039 0.0323 0.0544
Brugia malayi Cathepsin L-like precursor 0.0013 0.0018 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Echinococcus granulosus follistatin 0.0022 0.013 0.0262
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0171 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0055 0.0505 0.1019
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0021 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0041 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.003 0.0221 0.0372
Loa Loa (eye worm) hypothetical protein 0.0528 0.5943 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Onchocerca volvulus 0.0019 0.0089 0.0151
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0323 0.2538
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1274 0.2572
Brugia malayi hypothetical protein 0.0033 0.0249 0.0503
Brugia malayi conserved hypotetical protein 0.0026 0.0171 0.0346
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Brugia malayi SPARC precursor 0.0022 0.013 0.0262
Onchocerca volvulus 0.003 0.0221 0.0372
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0349
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0252 0.7795
Leishmania major hypothetical protein, conserved 0.0039 0.0323 0.2538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Brugia malayi 6-phosphofructokinase 0.0122 0.1275 0.2575
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Toxoplasma gondii ABC1 family protein 0.0039 0.0323 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0171 0.0346
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0505 0.1019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0323 0.2538
Leishmania major cathepsin L-like protease 0.0071 0.0696 0.546
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0121 0.0948
Leishmania major cathepsin L-like protease 0.0019 0.0089 0.0702
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0121 0.0121
Echinococcus multilocularis follistatin 0.0022 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0093 0.0157
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0349
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0121 0.0244
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0022 0.013 0.0219
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0089 0.355
Mycobacterium ulcerans 6-phosphofructokinase 0.0122 0.1274 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0057 0.1777
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0171 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0323 0.0323
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0089 0.355
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.0249 0.7699
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0121 0.0121
Echinococcus granulosus sodium bile acid cotransporter 0.0442 0.4953 1
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0033 0.0249 0.0249
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0121 0.0121
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0252 1
Entamoeba histolytica hypothetical protein 0.0021 0.0121 0.0948
Schistosoma mansoni zinc finger protein 0.0026 0.0171 0.0346
Onchocerca volvulus 0.0019 0.0089 0.0151
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0055 0.0505 0.1019
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0089 0.0181
Echinococcus granulosus bloom syndrome protein 0.0024 0.0149 0.03
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0089 0.0151
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0121 0.0121
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0505 0.1019
Loa Loa (eye worm) cysteine protease 0.0019 0.0089 0.0151
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0171 0.0346
Loa Loa (eye worm) hypothetical protein 0.0022 0.013 0.0219
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Schistosoma mansoni intermediate filament proteins 0.003 0.0221 0.0447
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0207 0.0418
Onchocerca volvulus 0.0033 0.0249 0.0419
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0089 0.0702
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Echinococcus multilocularis cysteine protease 0.0019 0.0089 0.0089
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Brugia malayi Nuclear hormone receptor-like 1 0.0207 0.2259 0.4561
Onchocerca volvulus 0.0033 0.0249 0.0419
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0249 0.0419
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0089 0.0181
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0022 0.013 0.0219
Schistosoma mansoni thyroid hormone receptor 0.0135 0.1431 0.2889
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0696 0.5385
Brugia malayi Nuclear hormone receptor-like 1 0.0182 0.1961 0.396
Loa Loa (eye worm) hypothetical protein 0.0019 0.0089 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0323 0.2538
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0081 0.08 0.1615
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.013 0.0262
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0252 0.7795
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.003 0.0215 0.0361
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0089 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0171 0.0346
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0252 0.1979
Schistosoma mansoni nuclear receptor 0.0026 0.0171 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0055 0.0505 0.1019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Echinococcus multilocularis geminin 0.0184 0.199 0.199
Mycobacterium tuberculosis Conserved protein 0.0039 0.0323 0.1178
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0121 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1274 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0055 0.0505 0.1019
Brugia malayi Phospholipase A2 family protein 0.0111 0.1152 0.2325
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0696 0.5385
Echinococcus multilocularis sodium bile acid cotransporter 0.0442 0.4953 0.4953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0122 0.1274 1
Leishmania major cathepsin L-like protease 0.0071 0.0696 0.546
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.013 0.0262
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0121 0.0121
Schistosoma mansoni agrin 0.0022 0.013 0.0262
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0505 0.0505
Brugia malayi beta-lactamase 0.0039 0.0323 0.0653
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.006 0.0101
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0178 0.1926 0.324
Onchocerca volvulus 0.0442 0.4953 0.8333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0018 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0121 0.0244
Schistosoma mansoni hypothetical protein 0.0184 0.199 0.4018
Loa Loa (eye worm) beta-lactamase 0.0039 0.0323 0.0544
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0055 0.0505 0.0849
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0055 0.0505 0.1019
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Onchocerca volvulus 0.0033 0.0249 0.0419
Echinococcus multilocularis sodium bile acid cotransporter 0.0442 0.4953 0.4953
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0249 0.0503
Brugia malayi nuclear receptor RXR 0.0029 0.0207 0.0418
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0033 0.0249 0.0419
Echinococcus multilocularis 6 phosphofructokinase 0.0122 0.1274 0.1274
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1274 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.0221 0.0372
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0121 0.0244
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0055 0.0505 0.0849
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0121 0.0244
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0089 0.0181
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0021 0.0162
Loa Loa (eye worm) fibroinase 0.0019 0.0089 0.0151
Loa Loa (eye worm) hypothetical protein 0.0022 0.013 0.0219
Echinococcus granulosus agrin 0.0022 0.013 0.0262
Brugia malayi hypothetical protein 0.0021 0.0121 0.0244
Toxoplasma gondii protease inhibitor PI2 0.0022 0.013 0.4018
Brugia malayi Cathepsin L-like precursor 0.0013 0.0018 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0059
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0171 0.0346
Schistosoma mansoni nuclear receptor 0.0026 0.0171 0.0346
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0323 0.1178
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0055 0.0505 0.1019
Echinococcus granulosus Solute carrier organic anion transporter family 0.0033 0.0249 0.0503
Echinococcus multilocularis expressed protein 0.0418 0.4682 0.4682
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0323 0.1178
Schistosoma mansoni sodium-bile acid cotransporter related 0.0442 0.4953 1
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0089 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0349
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0089 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0055 0.0505 0.1019
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0171 0.0289
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0121 0.0203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0149 0.0149
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0089 0.0151
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.013 0.4018
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.013 0.0262
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0021 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0018 0.0143
Loa Loa (eye worm) ctsf protein 0.0019 0.0089 0.0151
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0122 0.1274 0.4639
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0089 0.0151
Brugia malayi hypothetical protein 0.0026 0.0171 0.0346
Loa Loa (eye worm) hypothetical protein 0.0022 0.013 0.0219
Brugia malayi phosphofructokinase 0.0122 0.1274 0.2572
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Echinococcus multilocularis sodium bile acid cotransporter 0.0442 0.4953 0.4953
Entamoeba histolytica cysteine protease, putative 0.0019 0.0089 0.0702
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0055 0.0505 0.0505
Echinococcus granulosus expressed protein 0.0418 0.4682 0.9454
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0182 0.1961 0.33
Echinococcus multilocularis ecdysone induced protein 78C 0.0055 0.0505 0.0505
Brugia malayi nuclear hormone receptor 0.0026 0.0171 0.0346
Schistosoma mansoni lamin 0.003 0.0221 0.0447
Echinococcus multilocularis lamin dm0 0.003 0.0221 0.0221
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0089 0.0702
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0055 0.0505 0.1019
Toxoplasma gondii cathepsin CPL 0.0019 0.0089 0.2767
Brugia malayi hypothetical protein 0.0021 0.0121 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0055 0.0505 0.1019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0031
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0171 0.0346
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0055 0.0505 0.1019
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0121 0.0203
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0149 0.1167
Brugia malayi tailless protein 0.0026 0.0171 0.0346
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0171 0.0289
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.006 0.1845
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0149 0.1167
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0121 0.0203
Onchocerca volvulus 0.0013 0.0018 0.0031
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0033 0.0249 0.0249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0207 0.0418
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0033 0.0249 0.0503
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0323 0.1178
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0121 0.0244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0055 0.0505 0.0849
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0055 0.0505 0.1019
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0055 0.0505 0.1019
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0055 0.0505 0.0505
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0041 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Echinococcus granulosus geminin 0.0184 0.199 0.4018
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0252 0.1979
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0121 0.0203
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1274 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0505 0.1019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0171 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0018 0.0143
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0115 0.4574
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0031
Brugia malayi hypothetical protein 0.0029 0.0207 0.0418
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1274 0.2144
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0089 0.355
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0323 0.2416
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Brugia malayi ecdysteroid receptor 0.0055 0.0505 0.1019
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0171 0.0289
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0207 0.0418
Onchocerca volvulus 0.0019 0.0089 0.0151
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0055 0.0505 0.0505
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0018 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0323 1
Brugia malayi Sodium Bile acid symporter family protein 0.0442 0.4953 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0055 0.0505 0.0849
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0323 0.2538
Loa Loa (eye worm) steroid hormone receptor 0.0055 0.0505 0.0849
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0323 0.0653
Echinococcus granulosus intermediate filament protein 0.003 0.0221 0.0447
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0171 0.0171
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Brugia malayi PXA domain containing protein 0.0021 0.0121 0.0244
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0171 0.0346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Schistosoma mansoni steroid hormone receptor ad4bp 0.0055 0.0505 0.1019
Brugia malayi nuclear receptor RXR 0.0026 0.0171 0.0346
Onchocerca volvulus 0.0019 0.0089 0.0151
Schistosoma mansoni lamin 0.003 0.0221 0.0447
Echinococcus granulosus 6 phosphofructokinase 0.0122 0.1274 0.2572
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.052 0.3982
Leishmania major cathepsin L-like protease 0.0019 0.0089 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Brugia malayi nuclear receptor NHR-67 0.0026 0.0171 0.0346
Leishmania major cathepsin L-like protease 0.0019 0.0089 0.0702
Entamoeba histolytica hypothetical protein 0.0021 0.0121 0.0948
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0121 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Onchocerca volvulus 0.0055 0.0505 0.0849
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0089 0.0089
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1274 0.2144
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0121 0.0244
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0121 0.0121
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0323 0.0653
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0089 0.0549
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Echinococcus granulosus sodium bile acid cotransporter 0.0442 0.4953 1
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0121 0.0244
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1274 1
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0249 0.0503
Echinococcus granulosus FTZ F1 alpha 0.0055 0.0505 0.1019
Echinococcus granulosus sodium bile acid cotransporter 0.0442 0.4953 1
Brugia malayi beta-lactamase family protein 0.0039 0.0323 0.0653
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0323 0.1178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0089 0.0702
Leishmania major cathepsin L-like protease 0.0019 0.0089 0.0702
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0505 0.1019
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0349
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1274 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0089 0.0181
Loa Loa (eye worm) hypothetical protein 0.0029 0.0207 0.0349
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0207 0.0207
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0171 0.0346
Onchocerca volvulus Bile acid receptor homolog 0.0055 0.0505 0.0849
Trichomonas vaginalis esterase, putative 0.0039 0.0323 0.2538
Trypanosoma cruzi MFS transporter, putative 0.0033 0.0249 0.1822
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0055 0.0505 0.1019
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0059
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0323 0.1178
Mycobacterium tuberculosis Conserved protein 0.0039 0.0323 0.1178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0505 0.1019
Leishmania major cathepsin L-like protease 0.0019 0.0089 0.0702
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0055 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Onchocerca volvulus Protein ultraspiracle homolog 0.0055 0.0505 0.0849
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Onchocerca volvulus 0.0033 0.0249 0.0419
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0323 0.2416
Brugia malayi ecdysone receptor 0.0026 0.0171 0.0346
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0252 0.7795
Brugia malayi nuclear receptor NHR-88 0.0055 0.0505 0.1019
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0171 0.0346
Schistosoma mansoni hypothetical protein 0.0184 0.199 0.4018
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.013 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0121 0.0244
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0089 0.0089
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0121 0.0244
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0091 0.0183
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0055 0.0505 0.1019
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0171 0.0171
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0171 0.0346
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0121 0.0244
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0055 0.0505 0.1019
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0121 0.0244
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0252 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.013 0.4018
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0323 0.1178
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0696 0.5385
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0121 0.0121
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0252 0.1979
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0323 0.1178
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0249 0.0419
Loa Loa (eye worm) hypothetical protein 0.0039 0.0323 0.0544
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0122 0.1274 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.013 0.4018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0121 0.0121
Brugia malayi Nuclear hormone receptor-like 1 0.0182 0.1961 0.396
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0505 0.1019
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0121 0.0244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0055 0.0505 0.0849
Echinococcus multilocularis expressed protein 0.0022 0.013 0.013
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0121 0.0244
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0442 0.4953 0.8333
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0249 0.0503
Echinococcus multilocularis cysteine protease 0.0019 0.0089 0.0089
Schistosoma mansoni sodium-bile acid cotransporter related 0.0295 0.3262 0.6586
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0089 0.0702
Brugia malayi Steroid receptor seven-up type 2 0.0055 0.0505 0.1019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0505 0.1019
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0171 0.0346
Brugia malayi intermediate filament protein 0.003 0.0221 0.0447
Echinococcus granulosus cathepsin l1 0.0013 0.0018 0.0037
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0121 0.0244
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0252 0.7795
Onchocerca volvulus 0.0039 0.0323 0.0544
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0171 0.0346
Echinococcus granulosus ecdysone induced protein 78C 0.0055 0.0505 0.1019
Schistosoma mansoni thyroid hormone receptor 0.0135 0.1431 0.2889
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Schistosoma mansoni organic anion transporter 0.0033 0.0249 0.0503
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0171 0.0171
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0252 1
Onchocerca volvulus 0.0019 0.0089 0.0151
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0121 0.0203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Brugia malayi 6-phosphofructokinase 0.0122 0.1274 0.2572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Loa Loa (eye worm) agrin synaptic family protein 0.0022 0.013 0.0219
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1274 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0505 0.1019
Brugia malayi hypothetical protein 0.0033 0.0249 0.0503
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0033 0.0249 0.0419
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0031
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0171 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0089 0.0702
Onchocerca volvulus 0.0019 0.0089 0.0151
Echinococcus multilocularis thyroid hormone receptor alpha 0.0135 0.1431 0.1431
Brugia malayi secreted modular calcium-binding protein 1 0.0022 0.013 0.0262
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Brugia malayi hypothetical protein 0.0029 0.0207 0.0418
Schistosoma mansoni coup transcription factor 0.0055 0.0505 0.1019
Brugia malayi Cathepsin L-like precursor 0.0019 0.0089 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Echinococcus multilocularis FTZ F1 alpha 0.0055 0.0505 0.0505
Schistosoma mansoni nuclear hormone receptor 0.0055 0.0505 0.1019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Onchocerca volvulus Phospholipase A2 homolog 0.0528 0.5943 1
Leishmania major cathepsin L-like protease 0.0071 0.0696 0.546
Loa Loa (eye worm) hypothetical protein 0.0026 0.0171 0.0289
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0121 0.0244
Mycobacterium tuberculosis Conserved protein 0.0039 0.0323 0.1178
Schistosoma mansoni RAR-like nuclear receptor 0.0055 0.0505 0.1019
Schistosoma mansoni retinoic acid receptor RXR 0.0055 0.0505 0.1019
Onchocerca volvulus 0.0026 0.0171 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.0505 0.0849
Echinococcus multilocularis musashi 0.003 0.0221 0.0221
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0696 0.5385
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0121 0.0948
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0171 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Onchocerca volvulus 0.003 0.0221 0.0372
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.013 0.4018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.0203
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0089 0.0702
Brugia malayi hypothetical protein 0.0026 0.0171 0.0346
Onchocerca volvulus 0.0022 0.013 0.0219
Schistosoma mansoni organic anion transporter 0.0033 0.0249 0.0503
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0221 0.0447
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0121 0.0244
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0252 1
Onchocerca volvulus 0.0039 0.0323 0.0544
Plasmodium vivax vivapain-2 0.0019 0.0089 0.2767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0089 0.0702
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1274 0.2572
Loa Loa (eye worm) hypothetical protein 0.0111 0.1152 0.1938
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0624 0.4816
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0171 0.0346
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0249 0.0419

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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