Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | TAR-binding protein | 0.0124 | 0.4522 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0642 | 0.1039 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.4504 | 0.4397 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1319 | 0.115 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4522 | 0.4415 |
Echinococcus granulosus | tar DNA binding protein | 0.0124 | 0.4522 | 0.4415 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4522 | 0.4415 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4522 | 0.4415 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4522 | 0.4415 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1319 | 0.2604 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0028 | 0.0399 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.025 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0124 | 0.4522 | 0.4415 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.19 | 0.1742 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0063 | 0.19 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0124 | 0.4522 | 0.4415 |
Loa Loa (eye worm) | TAR-binding protein | 0.0124 | 0.4522 | 0.4415 |
Leishmania major | hypothetical protein, conserved | 0.0063 | 0.19 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.025 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4522 | 0.4415 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0399 | 0.0211 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0063 | 0.19 | 1 |
Trichomonas vaginalis | importin beta-1, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0124 | 0.4522 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0028 | 0.0399 | 0.0211 |
Echinococcus multilocularis | geminin | 0.0123 | 0.4504 | 0.4397 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0097 | 0.3375 | 0.3246 |
Echinococcus granulosus | geminin | 0.0123 | 0.4504 | 0.4397 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1319 | 0.115 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0063 | 0.19 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0063 | 0.19 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.4504 | 0.4397 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.025 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0124 | 0.4522 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1319 | 0.2604 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0063 | 0.19 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0642 | 0.0459 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0097 | 0.3375 | 0.3246 |
Entamoeba histolytica | hypothetical protein | 0.0019 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0935 | 0.1717 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0642 | 0.0459 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0124 | 0.4522 | 0.4415 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0063 | 0.19 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0067 | 0.2061 | 0.4316 |
Brugia malayi | hypothetical protein | 0.0063 | 0.19 | 0.3945 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0063 | 0.19 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0097 | 0.3375 | 0.7351 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.