Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.021 | 0.2782 | 0.2755 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.021 | 0.2782 | 0.2755 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0151 | 0.1964 | 0.1933 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0724 | 1 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.021 | 0.2782 | 0.2755 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0535 | 0.7348 | 0.7338 |
Leishmania major | prostaglandin f synthase, putative | 0.0724 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0724 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0514 | 0.7057 | 0.7046 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.021 | 0.2782 | 0.2755 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.021 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | oxidoreductase | 0.0724 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.021 | 0.2782 | 0.2755 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 0.3765 | 0.3742 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.021 | 0.2782 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0724 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0724 | 1 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0151 | 0.1964 | 0.1933 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.021 | 0.2782 | 0.2782 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.021 | 0.2782 | 0.2755 |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Echinococcus granulosus | snurportin 1 | 0.0151 | 0.1964 | 0.1933 |
Entamoeba histolytica | aldose reductase, putative | 0.0724 | 1 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.021 | 0.2782 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.7348 | 0.7338 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0724 | 1 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.004 | 0.0405 | 0.0368 |
Loa Loa (eye worm) | runx1 | 0.0067 | 0.0781 | 0.0746 |
Brugia malayi | NADH-dependent xylose reductase | 0.021 | 0.2782 | 0.2755 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.021 | 0.2782 | 0.2782 |
Echinococcus multilocularis | aldo keto reductase | 0.0724 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0724 | 1 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.021 | 0.2782 | 0.2782 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0724 | 1 | 1 |
Schistosoma mansoni | potassium channel beta | 0.021 | 0.2782 | 0.2755 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0514 | 0.7057 | 0.7046 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.021 | 0.2782 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.021 | 0.2782 | 0.2782 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.021 | 0.2782 | 0.2755 |
Toxoplasma gondii | aldose reductase, putative | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.021 | 0.2782 | 0.2782 |
Entamoeba histolytica | aldose reductase, putative | 0.0724 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0724 | 1 | 0.5 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.021 | 0.2782 | 0.2782 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.021 | 0.2782 | 0.2782 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0724 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0724 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.028 | 0.3765 | 0.3742 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0514 | 0.7057 | 0.5922 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Echinococcus granulosus | hypothetical protein | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0724 | 1 | 1 |
Onchocerca volvulus | 0.0535 | 0.7348 | 0.6326 | |
Schistosoma mansoni | lozenge | 0.0067 | 0.0781 | 0.0746 |
Loa Loa (eye worm) | oxidoreductase | 0.0724 | 1 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.021 | 0.2782 | 0.2755 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0724 | 1 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.021 | 0.2782 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0724 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.021 | 0.2782 | 0.2782 |
Trypanosoma cruzi | aldo-keto reductase | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0724 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0724 | 1 | 0.5 |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Onchocerca volvulus | 0.0724 | 1 | 1 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0724 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Toxoplasma gondii | aldo-keto reductase | 0.021 | 0.2782 | 0.2755 |
Loa Loa (eye worm) | oxidoreductase | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0724 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0724 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0724 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0724 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.7348 | 0.7338 |
Schistosoma mansoni | hypothetical protein | 0.0151 | 0.1964 | 0.1933 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0724 | 1 | 1 |
Echinococcus multilocularis | Protein lozenge | 0.0067 | 0.0781 | 0.0746 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.