Detailed information for compound 2075224

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 396.486 | Formula: C21H28N6O2
  • H donors: 0 H acceptors: 3 LogP: 1.85 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cn1c(=O)n(C)c2c(c1=O)n(CCCCN1CCN(CC1)c1ccccc1)cn2
  • InChi: 1S/C21H28N6O2/c1-23-19-18(20(28)24(2)21(23)29)27(16-22-19)11-7-6-10-25-12-14-26(15-13-25)17-8-4-3-5-9-17/h3-5,8-9,16H,6-7,10-15H2,1-2H3
  • InChiKey: SXXWLOKXKYIUHW-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Loa Loa (eye worm) hypothetical protein 0.006 0.066 0.0681
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0035
Echinococcus granulosus multidrug resistance protein 1 0.0073 0.085 0.0946
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Trypanosoma cruzi agmatinase, putative 0.0092 0.1143 0.8264
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.0123
Leishmania major hypothetical protein, conserved 0.0034 0.0249 0.0473
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Plasmodium vivax plasmepsin V, putative 0.0027 0.0146 0.0179
Entamoeba histolytica P-glycoprotein-2 0.0073 0.085 0.2204
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0073 0.085 0.0946
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0029 0.0177 0.1313
Mycobacterium ulcerans putative regulatory protein 0.0029 0.0177 0.1313
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0955 0.2648
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0057 0.0605 0.0673
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0177 0.0491
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0117 0.1526 0.7471
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0199 0.1477
Brugia malayi Carboxylesterase family protein 0.0102 0.1298 0.1394
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0102 0.1298 0.1443
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0071 0.0196
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0034 0.0249 0.0277
Schistosoma mansoni inositol monophosphatase 0.0035 0.0277 0.0227
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0023 0.0083 0.0035
Echinococcus multilocularis solute carrier family 5 0.0237 0.3366 0.3743
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0028 0.0162 0.018
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Brugia malayi MBOAT family protein 0.0034 0.0249 0.0222
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0073 0.085 0.2357
Echinococcus multilocularis para nitrobenzyl esterase 0.0102 0.1298 0.1443
Leishmania major glycerol uptake protein, putative 0.0034 0.0249 0.0473
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0022
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0075 0.0884 0.6595
Loa Loa (eye worm) hypothetical protein 0.0029 0.0177 0.0141
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0083 0.0092
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0121 0.1587 0.1765
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0249 0.0691
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0149 0.2015 0.2241
Entamoeba histolytica hypothetical protein, conserved 0.0034 0.0249 0.0505
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0406 0.0397
Mycobacterium ulcerans hypothetical protein 0.0026 0.013 0.0964
Onchocerca volvulus 0.0102 0.1298 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0249 0.0691
Leishmania major arginase 0.0253 0.3608 1
Leishmania major glycerol uptake protein, putative 0.0034 0.0249 0.0473
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0057 0.0605 0.062
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0237 0.3366 0.3743
Loa Loa (eye worm) hypothetical protein 0.0155 0.2117 0.231
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Loa Loa (eye worm) hypothetical protein 0.006 0.066 0.0681
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0034 0.0249 0.0277
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Leishmania major glycerol uptake protein, putative 0.0034 0.0249 0.0473
Loa Loa (eye worm) carboxylesterase 0.0102 0.1298 0.1394
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0223
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0057 0.0605 0.1678
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0223
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0023 0.0083 0.0599
Entamoeba histolytica ATP-binding cassette protein, putative 0.0023 0.0083 0.0034
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0149 0.2015 0.2241
Trichomonas vaginalis ABC transporter, putative 0.0073 0.085 0.2357
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0448
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0073 0.085 0.2357
Echinococcus multilocularis ATP binding cassette sub family B 0.0072 0.0838 0.0932
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0117 0.1526 0.165
Plasmodium vivax aspartyl proteinase, putative 0.0027 0.0146 0.0179
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0955 0.2648
Schistosoma mansoni inositol transporter 0.0237 0.3366 0.3331
Loa Loa (eye worm) MBOAT family protein 0.0034 0.0249 0.0222
Echinococcus granulosus sterol O acyltransferase 1 0.0189 0.2633 0.2928
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0027 0.0146 0.0106
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Trypanosoma brucei p-glycoprotein 0.0023 0.0083 0.0599
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.1168
Echinococcus multilocularis inositol monophosphatase 1 0.0035 0.0277 0.0308
Loa Loa (eye worm) MBOAT family protein 0.0034 0.0249 0.0222
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0028 0.0162 0.0223
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Schistosoma mansoni smdr2 0.0073 0.085 0.0803
Loa Loa (eye worm) hypothetical protein 0.0027 0.0146 0.0106
Entamoeba histolytica P-glycoprotein-1 0.0073 0.085 0.2204
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0028 0.0162 0.0123
Echinococcus multilocularis sterol O acyltransferase 1 0.0189 0.2633 0.2928
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0073 0.085 0.2177
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Plasmodium falciparum plasmepsin III 0.0027 0.0146 0.0179
Trichomonas vaginalis taga, putative 0.0073 0.085 0.2357
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0073 0.085 0.5
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0034 0.0249 0.0199
Brugia malayi ABC transporter transmembrane region family protein 0.0023 0.0083 0.0035
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Trypanosoma brucei multidrug resistance protein E 0.0023 0.0083 0.0599
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0028 0.0162 0.1168
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0023 0.0083 0.0599
Schistosoma mansoni hypothetical protein 0.0029 0.018 0.013
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.022 0.1128
Brugia malayi MBOAT family protein 0.0034 0.0249 0.0222
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0054 0.0557 0.4129
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0028 0.0162 0.018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trichomonas vaginalis abcb9, putative 0.0073 0.085 0.2357
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0028 0.0162 0.0223
Loa Loa (eye worm) carboxylesterase 0.0604 0.8991 1
Trypanosoma cruzi multidrug resistance protein E, putative 0.0023 0.0083 0.0599
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0406 0.0357
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0162 0.1168
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0028 0.0162 0.1168
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0955 0.2648
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0034 0.0249 0.0277
Entamoeba histolytica ATP-binding cassette protein, putative 0.0023 0.0083 0.0034
Onchocerca volvulus 0.006 0.066 0.4886
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0149 0.2015 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0073 0.085 0.0894
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0277 0.0767
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0162 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0162 0.0448
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0028 0.0162 0.1168
Schistosoma mansoni multidrug resistance protein 0.0023 0.0083 0.0032
Echinococcus multilocularis 0.0023 0.0083 0.0092
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0047 0.0457 0.3384
Echinococcus granulosus neuroligin 0.0102 0.1298 0.1443
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0023 0.0083 0.0599
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0043 0.0387 0.0375
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0023 0.0083 0.0599
Brugia malayi Carboxylesterase family protein 0.0102 0.1298 0.1394
Loa Loa (eye worm) aspartyl protease 6 0.0027 0.0146 0.0106
Entamoeba histolytica vacuolar protein sorting 26 0.0034 0.0249 0.0505
Trypanosoma brucei glycerol uptake protein, putative 0.0034 0.0249 0.1803
Loa Loa (eye worm) hypothetical protein 0.0027 0.0146 0.0106
Brugia malayi aspartic protease BmAsp-1, identical 0.0027 0.0146 0.0106
Trichomonas vaginalis inositol monophosphatase, putative 0.0035 0.0277 0.0767
Schistosoma mansoni high-affinity choline transporter 0.006 0.066 0.0612
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0073 0.085 0.0946
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0083 0.0092
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0028 0.0162 0.018
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0071 0.0196
Brugia malayi MH2 domain containing protein 0.0115 0.1489 0.1609
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0159 0.2174 0.6026
Echinococcus granulosus arginase 2 mitochondrial 0.0253 0.3608 0.4012
Loa Loa (eye worm) hypothetical protein 0.0043 0.0387 0.0375
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0073 0.085 0.2357
Giardia lamblia Multidrug resistance-associated protein 1 0.0023 0.0083 0.0063
Trichomonas vaginalis spcc417.12 protein, putative 0.0102 0.1298 0.3597
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0083 0.0092
Loa Loa (eye worm) ABC transporter 0.0023 0.0083 0.0035
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0117 0.1526 0.1483
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0022 0.0071 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Echinococcus granulosus acetylcholinesterase 0.0604 0.8991 1
Plasmodium falciparum plasmepsin I 0.0027 0.0146 0.0179
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0034 0.0249 0.0222
Echinococcus granulosus o acyltransferase membrane bound domain 0.0034 0.0249 0.0277
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0073 0.085 0.3972
Leishmania major cAMP-specific phosphodiesterase, putative 0.0028 0.0162 0.0223
Entamoeba histolytica P-glyco protein 6, putative 0.0073 0.085 0.2204
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0117 0.1526 0.4095
Echinococcus granulosus high affinity choline transporter 1 0.006 0.066 0.0734
Brugia malayi latrophilin 2 splice variant baaae 0.0029 0.018 0.0144
Plasmodium falciparum plasmepsin IV 0.0027 0.0146 0.0179
Trypanosoma cruzi GUP1, putative 0.0034 0.0249 0.1803
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0073 0.085 0.3972
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0277 0.2001
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0054 0.0557 0.4129
Toxoplasma gondii hypothetical protein 0.0034 0.0249 0.0862
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0102 0.1298 0.1253
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.006 0.066 0.0734
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0117 0.1526 0.1698
Loa Loa (eye worm) multidrug resistance protein 3 0.0073 0.085 0.0894
Toxoplasma gondii aspartyl protease 0.0027 0.0146 0.0326
Entamoeba histolytica Arginase, putative 0.0253 0.3608 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0073 0.085 0.0946
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Onchocerca volvulus 0.0027 0.0146 0.0759
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0028 0.0162 0.018
Brugia malayi aspartic protease BmAsp-2, identical 0.0027 0.0146 0.0106
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Schistosoma mansoni arginase 0.0253 0.3608 0.3575
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0406 0.0452
Brugia malayi MBOAT family protein 0.0034 0.0249 0.0222
Echinococcus granulosus sodium:glucose cotransporter 0.0237 0.3366 0.3743
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.022 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0073 0.085 0.0946
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Loa Loa (eye worm) hypothetical protein 0.0604 0.8991 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Giardia lamblia ABC transporter, putative 0.0023 0.0083 0.0063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0022
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0035 0.0277 0.205
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Onchocerca volvulus 0.0027 0.0146 0.0759
Schistosoma mansoni multidrug resistance protein 0.0023 0.0083 0.0032
Loa Loa (eye worm) ABC transporter 0.0023 0.0083 0.0035
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Leishmania major glycerol uptake protein, putative 0.0034 0.0249 0.0473
Brugia malayi ABC transporter transmembrane region family protein 0.0022 0.0071 0.0022
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0034 0.0249 0.0199
Schistosoma mansoni hypothetical protein 0.0034 0.0249 0.0199
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Plasmodium falciparum plasmepsin II 0.0027 0.0146 0.0179
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0034 0.0249 0.0277
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0034 0.0249 0.0277
Leishmania major hypothetical protein, conserved 0.0028 0.0162 0.0223
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0028 0.0162 0.1168
Trichomonas vaginalis aldehyde oxidase, putative 0.0159 0.2174 0.6026
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0028 0.0162 0.018
Loa Loa (eye worm) hypothetical protein 0.0034 0.0249 0.0222
Echinococcus granulosus multidrug resistance associated protein 1 0.0023 0.0083 0.0092
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0027 0.0146 0.0106
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0034 0.0249 0.0277
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0237 0.3366 0.3743
Trypanosoma brucei agmatinase, putative 0.0092 0.1143 0.8264
Brugia malayi Carboxylesterase family protein 0.0604 0.8991 1
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0028 0.0162 0.0223
Entamoeba histolytica multidrug resistance protein, putative 0.0023 0.0083 0.0034
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0035 0.0277 0.0583
Brugia malayi Carboxylesterase family protein 0.0604 0.8991 1
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0023 0.0083 0.0614
Trichomonas vaginalis Arginase, putative 0.0253 0.3608 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Schistosoma mansoni multidrug resistance protein 0.0023 0.0083 0.0032
Plasmodium vivax aspartyl protease, putative 0.0027 0.0146 0.0179
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0023 0.0083 0.0599
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0034 0.0249 0.0277
Loa Loa (eye worm) PDE1B protein 0.0028 0.0162 0.0123
Entamoeba histolytica hypothetical protein 0.0034 0.0249 0.0505
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0023 0.0083 0.023
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0035 0.0277 1
Trichomonas vaginalis abcb9, putative 0.0073 0.085 0.2357
Entamoeba histolytica ATP-binding cassette protein, putative 0.0023 0.0083 0.0034
Loa Loa (eye worm) hhat protein 0.0034 0.0249 0.0222
Plasmodium vivax aspartyl protease, putative 0.0027 0.0146 0.0179
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Plasmodium vivax arginase, putative 0.0253 0.3608 1
Brugia malayi ABC transporter 0.0023 0.0083 0.0035
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0028 0.0162 0.0123
Onchocerca volvulus 0.0102 0.1298 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Toxoplasma gondii aspartyl protease ASP3 0.0027 0.0146 0.0326
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0028 0.0162 0.0111
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0102 0.1298 0.1443
Treponema pallidum alginate O-acetylation protein (algI) 0.0034 0.0249 1
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0023 0.0083 0.0599
Giardia lamblia MRP-like ABC transporter 0.0023 0.0083 0.0063
Loa Loa (eye worm) hypothetical protein 0.0029 0.018 0.0144
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0057 0.0605 0.1678
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0223
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0027 0.0146 0.0326
Echinococcus granulosus acetylcholinesterase 0.0604 0.8991 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0079 0.0939 0.6792
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0073 0.085 0.2357
Entamoeba histolytica ATP-binding cassette protein, putative 0.0023 0.0083 0.0034
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0102 0.1298 1
Echinococcus granulosus multidrug resistance protein 1 0.0073 0.085 0.0946
Echinococcus granulosus multidrug resistance protein 1 0.0073 0.085 0.0946
Echinococcus granulosus multidrug resistance protein 1 0.0051 0.0513 0.0571
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0023 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0604 0.8991 1
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Echinococcus multilocularis peroxidasin 0.0021 0.0051 0.0057
Echinococcus multilocularis high affinity choline transporter 1 0.006 0.066 0.0734
Plasmodium falciparum plasmepsin X 0.0027 0.0146 0.0179
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Toxoplasma gondii hypothetical protein 0.0029 0.0177 0.0489
Mycobacterium ulcerans putative regulatory protein 0.0029 0.0177 0.1313
Echinococcus granulosus sodium:glucose cotransporter 2 0.0237 0.3366 0.3743
Echinococcus granulosus peroxidasin 0.0021 0.0051 0.0057
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0149 0.2015 1
Loa Loa (eye worm) MBOAT family protein 0.0034 0.0249 0.0222
Plasmodium vivax aspartyl protease, putative 0.0027 0.0146 0.0179
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0027 0.0146 0.0162
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0199 0.1477
Brugia malayi Hhat protein 0.0034 0.0249 0.0222
Plasmodium falciparum plasmepsin IX 0.0027 0.0146 0.0179
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0121 0.1587 0.1718
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0034 0.0249 0.0199
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0117 0.1526 0.1698
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0406 0.0397
Plasmodium falciparum arginase 0.0253 0.3608 1
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0108 0.1383 0.1538
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0079 0.0939 0.2604
Treponema pallidum hypothetical protein 0.0026 0.013 0.3699
Brugia malayi ABC transporter transmembrane region family protein 0.0023 0.0083 0.0035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0604 0.8991 0.8986
Brugia malayi hypothetical protein 0.0027 0.0146 0.0106
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0073 0.085 0.2357
Brugia malayi hypothetical protein 0.0027 0.0146 0.0106
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0105 0.135 1
Schistosoma mansoni multidrug resistance protein 0.0023 0.0083 0.0032
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0448
Echinococcus multilocularis arginase 2, mitochondrial 0.0253 0.3608 0.4012
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0071 0.0196
Giardia lamblia Hypothetical protein 0.0028 0.0162 0.0467
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0406 0.0357
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0159 0.2174 0.6026
Brugia malayi Pepsin A precursor 0.0027 0.0146 0.0106
Brugia malayi Calcitonin receptor-like protein seb-1 0.0043 0.0387 0.0375
Echinococcus multilocularis multidrug resistance associated protein 1 0.0023 0.0083 0.0092
Toxoplasma gondii hypothetical protein 0.008 0.0955 0.4515
Schistosoma mansoni BC026374 protein (S09 family) 0.0102 0.1298 0.1253
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0406 0.0452
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0057 0.0605 0.062
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Plasmodium falciparum phosphodiesterase gamma, putative 0.0028 0.0162 0.0223
Brugia malayi multidrug resistance protein 3 0.0073 0.085 0.0894
Brugia malayi diacylglycerol acyltransferase 0.0117 0.1526 0.165
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Schistosoma mansoni cathepsin D (A01 family) 0.0027 0.0146 0.0095
Echinococcus multilocularis 0.0253 0.3608 0.4012
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1489 0.1609
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0073 0.085 0.0946
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Brugia malayi multidrug resistance related protein 1 0.0023 0.0083 0.0035
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0277 0.0767
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0149 0.2015 0.2241
Plasmodium vivax aspartyl proteinase, putative 0.0027 0.0146 0.0179
Echinococcus granulosus ATP binding cassette sub family B 0.0023 0.0083 0.0092
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0023 0.0083 0.0614
Schistosoma mansoni multidrug resistance protein 0.0023 0.0083 0.0032
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0027 0.0146 0.0404
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0029 0.0177 0.0777
Brugia malayi P-glycoprotein-like protein 0.0023 0.0083 0.0035
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0034 0.0249 0.0199
Loa Loa (eye worm) inositol-1 0.0035 0.0277 0.0252
Plasmodium falciparum plasmepsin VI 0.0027 0.0146 0.0179
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Echinococcus granulosus multidrug resistance protein 1 0.0051 0.0513 0.0571
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Plasmodium vivax multidrug resistance protein 1, putative 0.0073 0.085 0.2177
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0023 0.0083 0.0599
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0073 0.085 0.0946
Trichomonas vaginalis abcb9, putative 0.0073 0.085 0.2357
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Brugia malayi ABC transporter family protein 0.0023 0.0083 0.0035
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0108 0.1383 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Schistosoma mansoni acetylcholinesterase 0.0102 0.1298 0.1253
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0028 0.0162 0.1168
Brugia malayi Carboxylesterase family protein 0.0102 0.1298 0.1394
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0223
Echinococcus multilocularis BC026374 protein (S09 family) 0.0102 0.1298 0.1443
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0034 0.0249 0.0277
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.006 0.066 0.2989
Brugia malayi GH02984p 0.006 0.066 0.0681
Trypanosoma cruzi glycerol uptake protein, putative 0.0034 0.0249 0.1803
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0406 0.0452
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Onchocerca volvulus 0.0102 0.1298 1
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0028 0.0162 0.0111
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0102 0.1298 0.1253
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0277 0.2001
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0034 0.0249 0.0505
Brugia malayi ABC transporter family protein 0.0023 0.0083 0.0035
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0028 0.0162 0.1168
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0073 0.085 0.2357
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0027 0.0146 0.0326
Loa Loa (eye worm) hypothetical protein 0.0027 0.0146 0.0106
Echinococcus multilocularis multidrug resistance protein 1 0.0051 0.0513 0.0571
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0051 0.0513 0.1422
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0149 0.2015 0.1974
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0054 0.0557 0.3906
Brugia malayi hypothetical protein 0.0102 0.1298 0.1394
Entamoeba histolytica P-glycoprotein-2, putative 0.0073 0.085 0.2204
Trypanosoma cruzi glycerol uptake protein, putative 0.0034 0.0249 0.1803
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0035
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0073 0.085 0.2357
Onchocerca volvulus 0.0102 0.1298 1
Schistosoma mansoni cathepsin D (A01 family) 0.0027 0.0146 0.0095
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0149 0.2015 0.2241
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0035
Brugia malayi ABC transporter 0.0022 0.0071 0.0022
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0028 0.0162 0.018
Brugia malayi ABC transporter family protein 0.0023 0.0083 0.0035
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0023 0.0083 0.0032
Brugia malayi MBOAT family protein 0.0034 0.0249 0.0222
Mycobacterium leprae conserved hypothetical protein 0.0029 0.0177 0.689
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Leishmania major agmatinase-like protein 0.0092 0.1143 0.3008
Leishmania major hypothetical protein, conserved 0.0028 0.0162 0.0223
Loa Loa (eye worm) hypothetical protein 0.0073 0.085 0.0894
Trypanosoma cruzi arginase, putative 0.0092 0.1143 0.8264
Echinococcus multilocularis multidrug resistance protein 1 0.0073 0.085 0.0946
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0121 0.1587 0.1718
Echinococcus granulosus para nitrobenzyl esterase 0.0102 0.1298 0.1443
Echinococcus multilocularis carboxylesterase 5A 0.0604 0.8991 1
Entamoeba histolytica P-glycoprotein-5 0.0073 0.085 0.2204
Echinococcus multilocularis acetylcholinesterase 0.0604 0.8991 1
Toxoplasma gondii hypothetical protein 0.0029 0.0177 0.0489
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0035 0.0277 0.1004
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0448
Loa Loa (eye worm) hypothetical protein 0.0057 0.0605 0.062
Loa Loa (eye worm) hypothetical protein 0.0189 0.2633 0.2887
Trypanosoma cruzi GUP1, putative 0.0034 0.0249 0.1803
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0108 0.1383 0.1339
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.1383 0.3834
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.0123
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0108 0.1383 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.1168
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0083 0.0092
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Trypanosoma brucei glycerol uptake protein, putative 0.0034 0.0249 0.1803
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0023 0.0083 0.0614
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0223
Echinococcus multilocularis acetylcholinesterase 0.0604 0.8991 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0043 0.0387 0.0375
Entamoeba histolytica P-glycoprotein 6, putative 0.0023 0.0083 0.0034
Schistosoma mansoni multidrug resistance protein 0.0073 0.085 0.0803
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0102 0.1298 0.1253
Loa Loa (eye worm) hypothetical protein 0.0083 0.101 0.1073
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0079 0.0939 0.2604
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0075 0.0884 0.6549
Plasmodium vivax phosphodiesterase gamma, putative 0.0028 0.0162 0.0223
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0028 0.0162 0.0123
Brugia malayi Sodium:solute symporter family protein 0.006 0.066 0.0681
Schistosoma mansoni zinc finger protein 0.0034 0.0249 0.0199
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0162 0.0123
Schistosoma mansoni gliotactin 0.0102 0.1298 0.1253
Echinococcus granulosus o acyltransferase membrane bound domain 0.0034 0.0249 0.0277
Schistosoma mansoni neuroligin 3 (S09 family) 0.0102 0.1298 0.1253
Plasmodium vivax plasmepsin IV, putative 0.0027 0.0146 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0253 0.3608 1
Plasmodium falciparum plasmepsin VIII, putative 0.0027 0.0146 0.0179
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0177 0.0268
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0277 0.2001
Echinococcus granulosus carboxylesterase 5A 0.0604 0.8991 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0073 0.085 0.0946
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.006 0.066 0.0734
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0023 0.0083 0.0614
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0277 0.055
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Mycobacterium tuberculosis Carboxylesterase LipT 0.0102 0.1298 1
Entamoeba histolytica ABC transporter, putative 0.0023 0.0083 0.0034
Entamoeba histolytica P-glycoprotein 5, putative 0.0073 0.085 0.2204
Plasmodium falciparum multidrug resistance protein 1 0.0073 0.085 0.2177
Trichomonas vaginalis ABC transporter, putative 0.0073 0.085 0.2357
Trichomonas vaginalis porcupine, putative 0.0034 0.0249 0.0691
Schistosoma mansoni multidrug resistance protein 0.0073 0.085 0.0803
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0034 0.0249 0.0505
Schistosoma mansoni sterol O-acyltransferase 1 0.0189 0.2633 0.2595
Echinococcus granulosus ATP binding cassette sub family B 0.0022 0.0071 0.0079
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0073 0.085 0.0946
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0075 0.0884 0.6549
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0034 0.0249 0.0199
Leishmania major p-glycoprotein 0.0073 0.085 0.2177
Trichomonas vaginalis conserved hypothetical protein 0.0253 0.3608 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0023 0.0083 0.0063
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0034 0.0249 0.0277
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Brugia malayi hypothetical protein 0.0023 0.0083 0.0035
Trichomonas vaginalis transmembrane protein nessy, putative 0.0034 0.0249 0.0691
Echinococcus granulosus 3'partial|arginase 2 mitochondrial 0.0253 0.3608 0.4012
Brugia malayi ABC transporter family protein 0.0073 0.085 0.0894
Echinococcus granulosus ATP binding cassette sub family B 0.0023 0.0083 0.0092
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Plasmodium falciparum GAF domain-related protein, putative 0.0029 0.0177 0.0268
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0249 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0162 0.0448
Loa Loa (eye worm) hhat protein 0.0034 0.0249 0.0222
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0102 0.1298 1
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0108 0.1383 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0162 0.0111
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trypanosoma cruzi glycerol uptake protein, putative 0.0034 0.0249 0.1803
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0102 0.1298 0.3597
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0028 0.0162 0.018
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0027 0.0146 0.0095
Echinococcus granulosus BC026374 protein S09 family 0.0102 0.1298 0.1443
Onchocerca volvulus 0.0102 0.1298 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0162 0.0448
Loa Loa (eye worm) hypothetical protein 0.0102 0.1298 0.1394
Trypanosoma cruzi agmatinase, putative 0.0092 0.1143 0.8264
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Schistosoma mansoni multidrug resistance protein 0.0022 0.0071 0.002
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0073 0.085 0.0946
Onchocerca volvulus 0.0073 0.085 0.6409
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0073 0.085 0.2357
Echinococcus granulosus inositol monophosphatase 1 0.0035 0.0277 0.0308
Plasmodium falciparum plasmepsin VII 0.0027 0.0146 0.0179
Schistosoma mansoni sodium/solute symporter 0.006 0.066 0.0612
Echinococcus multilocularis multidrug resistance associated protein 7 0.0023 0.0083 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Echinococcus granulosus o acyltransferase membrane bound domain 0.0034 0.0249 0.0277
Loa Loa (eye worm) hypothetical protein 0.0034 0.0249 0.0222
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0034 0.0249 0.0277
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0028 0.0162 0.018
Schistosoma mansoni smdr1 0.0023 0.0083 0.0032
Loa Loa (eye worm) hypothetical protein 0.0034 0.0249 0.0222
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0023 0.0083 0.0599
Schistosoma mansoni multidrug resistance protein 0.0073 0.085 0.0803
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0057 0.0605 0.0557
Echinococcus multilocularis multidrug resistance protein 1 0.0073 0.085 0.0946
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0029 0.0177 0.0777
Plasmodium falciparum plasmepsin V 0.0027 0.0146 0.0179
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0117 0.1526 0.4095
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0034 0.0249 0.0277
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0108 0.1383 0.1538
Echinococcus granulosus sodium:myo inositol cotransporter 0.0237 0.3366 0.3743
Loa Loa (eye worm) hypothetical protein 0.0072 0.0838 0.088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0073 0.085 0.2357
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0108 0.1383 0.3834
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0108 0.1383 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0071 0.0196
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0108 0.1383 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Loa Loa (eye worm) acetylcholinesterase 1 0.0604 0.8991 1
Trypanosoma cruzi arginase, putative 0.0092 0.1143 0.8264
Loa Loa (eye worm) carboxylesterase 0.0102 0.1298 0.1394
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0406 0.0357
Toxoplasma gondii GAF domain-containing protein 0.0029 0.0177 0.0489
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0057 0.0605 0.0673
Loa Loa (eye worm) ABC transporter 0.0023 0.0083 0.0035
Echinococcus multilocularis neuroligin 0.0102 0.1298 0.1443
Leishmania major glycerol uptake protein, putative 0.0034 0.0249 0.0473
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0108 0.1383 0.3834
Entamoeba histolytica P-glycoprotein 6, putative 0.0023 0.0083 0.0034
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1489 0.1609
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0117 0.1526 0.7471
Brugia malayi MBOAT family protein 0.0034 0.0249 0.0222
Loa Loa (eye worm) hypothetical protein 0.0149 0.2015 0.2196
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0108 0.1383 0.3834
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.003 0.0199 0.0959
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0121 0.1587 0.1765
Brugia malayi Carboxylesterase family protein 0.0102 0.1298 0.1394
Loa Loa (eye worm) hypothetical protein 0.0073 0.085 0.0894
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0027 0.0146 0.0162
Brugia malayi Eukaryotic aspartyl protease family protein 0.0027 0.0146 0.0106
Treponema pallidum quinoline 2-oxidoreductase 0.0025 0.0121 0.3211
Trichomonas vaginalis ABC transporter, putative 0.0073 0.085 0.2357
Schistosoma mansoni inositol monophosphatase 0.0035 0.0277 0.0227
Mycobacterium ulcerans carboxylesterase, LipT 0.0102 0.1298 0.9613
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0162 0.1168
Plasmodium falciparum phosphodiesterase delta, putative 0.0028 0.0162 0.0223
Echinococcus granulosus solute carrier family 5 0.0237 0.3366 0.3743
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0034 0.0249 0.0505
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0057 0.0605 0.1678
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0406 0.0452
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0162 0.0407
Entamoeba histolytica hypothetical protein 0.0023 0.0083 0.0034
Toxoplasma gondii aspartyl protease ASP1 0.0027 0.0146 0.0326
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0023 0.0083 0.0614
Echinococcus granulosus multidrug resistance associated protein 7 0.0023 0.0083 0.0092
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0108 0.1383 0.3834
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0073 0.085 0.6316
Entamoeba histolytica P-glycoprotein-2 0.0073 0.085 0.2204
Brugia malayi Inositol-1 0.0035 0.0277 0.0252
Schistosoma mansoni inositol transporter 0.0237 0.3366 0.3331
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0162 0.0448
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0072 0.0838 0.0932
Onchocerca volvulus 0.0034 0.0249 0.159
Trichomonas vaginalis ABC transporter, putative 0.0073 0.085 0.2357
Giardia lamblia hypothetical protein 0.0028 0.0162 0.0467

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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