Detailed information for compound 2075321

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 289.376 | Formula: C15H23N5O
  • H donors: 1 H acceptors: 3 LogP: -0.34 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)N1CCN(CC1)c1cncc(n1)C1CCNCC1
  • InChi: 1S/C15H23N5O/c1-12(21)19-6-8-20(9-7-19)15-11-17-10-14(18-15)13-2-4-16-5-3-13/h10-11,13,16H,2-9H2,1H3
  • InChiKey: DXBRWIPBQRBVNO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi ecdysone receptor 0.0033 0.0041 0.0183
Trypanosoma brucei histone deacetylase 1 0.0753 0.2238 1
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0069 0.0152 0.068
Echinococcus granulosus histone deacetylase 6 0.0304 0.0868 0.3878
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0069 0.0152 0.068
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0753 0.2238 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0069 0.0152 0.068
Brugia malayi Histone deacetylase family protein 0.0304 0.0868 0.3878
Echinococcus multilocularis lamin 0.0033 0.0041 0.0184
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0069 0.0152 0.068
Echinococcus multilocularis histone deacetylase 7 0.0304 0.0868 0.3878
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0067 0.0301
Echinococcus granulosus transcription factor btf3 0.0042 0.0071 0.0315
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Echinococcus granulosus histone deacetylase 0.0304 0.0868 0.3878
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0069 0.0152 0.068
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0125 0.0561
Brugia malayi nuclear receptor NHR-67 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0069 0.0152 0.068
Onchocerca volvulus 0.0048 0.0088 0.0631
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0041 0.0183
Loa Loa (eye worm) histone deacetylase 7A 0.0304 0.0868 0.3878
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0041 0.0183
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0041 0.0183
Plasmodium vivax cysteine--tRNA ligase, putative 0.0048 0.0088 0.0395
Trypanosoma brucei histone deacetylase 2 0.0279 0.0793 0.3542
Schistosoma mansoni transcription factor btf3 0.0042 0.0071 0.0315
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0048 0.0088 0.0395
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0069 0.0152 0.068
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0048 0.0088 0.5
Brugia malayi hypothetical protein 0.0033 0.0041 0.0183
Schistosoma mansoni lamin 0.0033 0.0041 0.0184
Echinococcus granulosus ecdysone induced protein 78C 0.0069 0.0152 0.068
Brugia malayi nuclear receptor NHR-88 0.0069 0.0152 0.068
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0041 0.0183
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0041 0.0183
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Echinococcus granulosus lamin 0.0033 0.0041 0.0184
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0041 0.0183
Echinococcus granulosus tar DNA binding protein 0.0076 0.0175 0.0783
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0069 0.0152 0.068
Schistosoma mansoni steroid hormone receptor ad4bp 0.0069 0.0152 0.068
Leishmania major histone deacetylase, putative 0.0753 0.2238 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0069 0.0152 0.068
Schistosoma mansoni hypothetical protein 0.0205 0.0566 0.2529
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0053 0.0236
Plasmodium vivax histone deacetylase 2, putative 0.0304 0.0868 0.3878
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0041 0.0183
Brugia malayi Cytochrome P450 family protein 0.0043 0.0073 0.0324
Loa Loa (eye worm) RNA binding protein 0.0076 0.0175 0.0783
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0069 0.0152 0.068
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0048 0.0088 0.0395
Schistosoma mansoni histone deacetylase 4 5 0.0304 0.0868 0.3878
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0069 0.0152 0.068
Schistosoma mansoni hypothetical protein 0.0041 0.0067 0.0301
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0036 0.0053 0.0236
Schistosoma mansoni histone deacetylase hda2 0.0279 0.0793 0.3542
Trypanosoma brucei histone deacetylase 4 0.0304 0.0868 0.3878
Loa Loa (eye worm) histone deacetylase 1 0.0753 0.2238 1
Echinococcus multilocularis histone deacetylase 1 0.0753 0.2238 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0041 0.0183
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0041 0.0183
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0041 0.0183
Plasmodium vivax histone deacetylase, putative 0.0304 0.0868 0.3878
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0041 0.0184
Schistosoma mansoni histone deacetylase 4 5 0.0304 0.0868 0.3878
Brugia malayi Steroid receptor seven-up type 2 0.0069 0.0152 0.068
Brugia malayi RNA binding protein 0.0076 0.0175 0.0783
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0175 0.0783
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0069 0.0152 0.068
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0175 0.0783
Brugia malayi nuclear receptor RXR 0.0033 0.0041 0.0183
Echinococcus multilocularis geminin 0.0205 0.0566 0.2529
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0125 0.0561
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0073 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0069 0.0152 0.068
Brugia malayi conserved hypotetical protein 0.0033 0.0041 0.0183
Brugia malayi ecdysteroid receptor 0.0069 0.0152 0.068
Treponema pallidum cysteinyl-tRNA synthetase 0.0048 0.0088 0.5
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0082
Echinococcus granulosus FTZ F1 alpha 0.0069 0.0152 0.068
Toxoplasma gondii histone deacetylase HDAC5 0.0279 0.0793 0.3542
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0036 0.0053 0.0236
Echinococcus multilocularis thyroid hormone receptor alpha 0.0069 0.0152 0.068
Leishmania major cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0395
Brugia malayi Histone deacetylase family protein 0.0304 0.0868 0.3878
Toxoplasma gondii histone deacetylase HDAC1 0.0304 0.0868 0.3878
Onchocerca volvulus 0.0033 0.0041 0.0002
Brugia malayi histone deacetylase 3 (HD3) 0.0753 0.2238 1
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0753 0.2238 1
Brugia malayi Nuclear hormone receptor-like 1 0.0069 0.0152 0.068
Trypanosoma cruzi histone deacetylase, putative 0.0304 0.0868 0.3878
Brugia malayi Nuclear hormone receptor-like 1 0.0036 0.0053 0.0236
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0279 0.0793 0.3542
Schistosoma mansoni nuclear hormone receptor 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0236
Schistosoma mansoni lamin 0.0033 0.0041 0.0184
Trypanosoma brucei histone deacetylase, putative 0.0304 0.0868 0.3878
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Echinococcus multilocularis histone deacetylase 6 0.0309 0.0884 0.3951
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0041 0.0184
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0069 0.0152 0.068
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0048 0.0088 0.0016
Echinococcus multilocularis transcription factor btf3 0.0042 0.0071 0.0315
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0073 0.0324
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0156
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0069 0.0152 0.068
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0069 0.0152 0.068
Brugia malayi photoreceptor-specific nuclear receptor 0.0069 0.0152 0.068
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0069 0.0152 0.068
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0069 0.0152 0.068
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Plasmodium falciparum cysteine--tRNA ligase 0.0048 0.0088 0.0395
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0041 0.0183
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0041 0.0183
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0149
Loa Loa (eye worm) DR-78 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0041 0.0067 0.0301
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Schistosoma mansoni zinc finger protein 0.0033 0.0041 0.0183
Schistosoma mansoni intermediate filament proteins 0.0033 0.0041 0.0184
Echinococcus multilocularis histone deacetylase 6 0.0304 0.0868 0.3878
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0071 0.0315
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0041 0.0183
Brugia malayi steroid hormone receptor 0.0069 0.0152 0.068
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0175 0.0783
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0041 0.0183
Schistosoma mansoni hypothetical protein 0.0205 0.0566 0.2529
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.3296 1 1
Toxoplasma gondii histone deacetylase HDAC4 0.0279 0.0793 0.3542
Echinococcus multilocularis lamin dm0 0.0033 0.0041 0.0184
Echinococcus granulosus histone deacetylase 6 0.0309 0.0884 0.3951
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0048 0.0088 0.0395
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0041 0.0184
Brugia malayi histone deacetylase 11 0.0279 0.0793 0.3542
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0069 0.0152 0.068
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0395
Plasmodium falciparum histone deacetylase 2 0.0304 0.0868 0.3878
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0395
Schistosoma mansoni histone deacetylase hda2 0.0309 0.0884 0.3951
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0236
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0036 0.0053 0.0236
Echinococcus multilocularis histone deacetylase 8 0.0279 0.0793 0.3542
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0236
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0048 0.0088 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0069 0.0152 0.068
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.0073 0.0324
Echinococcus multilocularis histone deacetylase 3 0.0753 0.2238 1
Echinococcus granulosus geminin 0.0205 0.0566 0.2529
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi nuclear receptor RXR 0.0036 0.0053 0.0236
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0036 0.0053 0.0236
Brugia malayi nuclear receptor NHR-88 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Echinococcus multilocularis FTZ F1 alpha 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Chlamydia trachomatis cysteine--tRNA ligase 0.0048 0.0088 0.5
Brugia malayi tailless protein 0.0033 0.0041 0.0183
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.0795 0.3553
Echinococcus granulosus histone deacetylase 6 0.0304 0.0868 0.3878
Trypanosoma cruzi histone deacetylase 1, putative 0.0753 0.2238 1
Onchocerca volvulus Histone deacetylase 10 homolog 0.0279 0.0793 1
Loa Loa (eye worm) steroid hormone receptor 0.0069 0.0152 0.068
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0175 0.0783
Echinococcus granulosus intermediate filament protein 0.0033 0.0041 0.0184
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0041 0.0183
Entamoeba histolytica histone deacetylase, putative 0.0753 0.2238 1
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.0071 0.0315
Brugia malayi hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi histone deacetylase 1 (HD1) 0.0753 0.2238 1
Trypanosoma brucei histone deacetylase 3 0.0304 0.0868 0.3878
Onchocerca volvulus Bile acid receptor homolog 0.0069 0.0152 0.1478
Brugia malayi nuclear hormone receptor 0.0069 0.0152 0.068
Schistosoma mansoni thyroid hormone receptor 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0175 0.0783
Echinococcus multilocularis ecdysone induced protein 78C 0.0069 0.0152 0.068
Loa Loa (eye worm) CYP4Cod1 0.0043 0.0073 0.0324
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0069 0.0152 0.068
Brugia malayi Histone deacetylase 1 0.0753 0.2238 1
Plasmodium falciparum cysteine--tRNA ligase 0.0048 0.0088 0.0395
Loa Loa (eye worm) hypothetical protein 0.006 0.0125 0.0561
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.0071 0.0315
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0071 0.0315
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0048 0.0088 0.0395
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0175 0.0783
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0236
Onchocerca volvulus Protein ultraspiracle homolog 0.0069 0.0152 0.1478
Brugia malayi beta-NAC-like protein 0.0042 0.0071 0.0315
Plasmodium falciparum histone deacetylase, putative 0.0304 0.0868 0.3878
Onchocerca volvulus 0.0033 0.0041 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0069 0.0152 0.068
Toxoplasma gondii NAC domain-containing protein 0.0042 0.0071 0.0315
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Schistosoma mansoni nuclear receptor 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Plasmodium falciparum histone deacetylase 1 0.0753 0.2238 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi nuclear hormone receptor 0.0033 0.0041 0.0183
Leishmania major histone deacetylase, putative 0.0753 0.2238 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0175 0.0783
Plasmodium vivax histone deacetylase, putative 0.0279 0.0793 0.3542
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Leishmania major cytochrome p450-like protein 0.0043 0.0073 0.0324
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0753 0.2238 1
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.0071 0.0315
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0041 0.0183
Onchocerca volvulus 0.0069 0.0152 0.1478
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0069 0.0152 0.068
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0069 0.0152 0.068
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.3296 1 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0152 0.0404 0.1806
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0175 0.0783
Trypanosoma cruzi histone deacetylase, putative 0.0279 0.0793 0.3542
Echinococcus granulosus histone deacetylase 8 0.0279 0.0793 0.3542
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0041 0.0183
Toxoplasma gondii histone deacetylase HDAC3 0.0753 0.2238 1
Brugia malayi follicle stimulating hormone receptor 0.028 0.0795 0.3553
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0175 0.0783
Schistosoma mansoni coup transcription factor 0.0069 0.0152 0.068
Loa Loa (eye worm) hypothetical protein 0.0753 0.2238 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0069 0.0152 0.068
Echinococcus granulosus leucyl tRNA synthetase 0.0048 0.0088 0.0395
Loa Loa (eye worm) hypothetical protein 0.0069 0.0152 0.068
Schistosoma mansoni thyroid hormone receptor 0.0069 0.0152 0.068
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0041 0.0183
Echinococcus granulosus histone deacetylase 7 0.0304 0.0868 0.3878
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0041 0.0183
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0176
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0184
Schistosoma mansoni RAR-like nuclear receptor 0.0069 0.0152 0.068
Schistosoma mansoni retinoic acid receptor RXR 0.0188 0.0515 0.2303
Trypanosoma cruzi histone deacetylase, putative 0.0304 0.0868 0.3878
Schistosoma mansoni histone deacetylase 1 2 3 0.0279 0.0793 0.3542
Echinococcus granulosus histone deacetylase 1 0.0753 0.2238 1
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0236
Echinococcus granulosus histone deacetylase 3 0.0753 0.2238 1
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0041 0.0183
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0041 0.0183
Loa Loa (eye worm) ICD-1 protein 0.0042 0.0071 0.0315
Giardia lamblia Histone deacetylase 0.0753 0.2238 1
Schistosoma mansoni histone deacetylase 0.0753 0.2238 1
Leishmania major basic transcription factor 3a, putative 0.0042 0.0071 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0069 0.0152 0.068
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0069 0.0152 0.068
Loa Loa (eye worm) histone deacetylase 11 0.0279 0.0793 0.3542
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0048 0.0088 0.0395
Brugia malayi hypothetical protein 0.0036 0.0053 0.0236
Loa Loa (eye worm) hypothetical protein 0.0033 0.0041 0.0183
Brugia malayi TAR-binding protein 0.0076 0.0175 0.0783
Loa Loa (eye worm) histone deacetylase 3 0.0753 0.2238 1
Echinococcus granulosus lamin dm0 0.0033 0.0041 0.0184
Leishmania major histone deacetylase, putative 0.0304 0.0868 0.3878
Echinococcus multilocularis histone deacetylase 0.0304 0.0868 0.3878
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Trypanosoma brucei cytochrome P450, putative 0.0043 0.0073 0.0324
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0069 0.0152 0.068
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0125 0.0561
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0036 0.0053 0.0236
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0075
Schistosoma mansoni histone deacetylase 0.0753 0.2238 1
Plasmodium vivax histone deacetylase 1, putative 0.0753 0.2238 1
Toxoplasma gondii histone deacetylase HDAC2 0.0753 0.2238 1
Brugia malayi hypothetical protein 0.0036 0.0053 0.0236
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0041 0.0183
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.0073 0.0324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0069 0.0152 0.068
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0048 0.0088 0.0395
Trypanosoma cruzi histone deacetylase, putative 0.0304 0.0868 0.3878
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0069 0.0152 0.068
Echinococcus granulosus cysteinyl tRNA synthetase 0.0048 0.0088 0.0395
Trypanosoma cruzi histone deacetylase, putative 0.0279 0.0793 0.3542
Leishmania major histone deacetylase, putative 0.0304 0.0868 0.3878
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0069 0.0152 0.068
Brugia malayi Cytochrome P450 family protein 0.0043 0.0073 0.0324
Echinococcus multilocularis histone deacetylase 6 0.0304 0.0868 0.3878
Brugia malayi intermediate filament protein 0.0033 0.0041 0.0184
Schistosoma mansoni nuclear receptor 0.0033 0.0041 0.0183
Trypanosoma cruzi histone deacetylase 1, putative 0.0753 0.2238 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0069 0.0152 0.1478
Trichomonas vaginalis histone deacetylase, putative 0.0753 0.2238 1
Loa Loa (eye worm) histone deacetylase 0.0304 0.0868 0.3878
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0048 0.0088 0.0395
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0041 0.0183
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0188 0.0515 0.2303
Echinococcus multilocularis musashi 0.0033 0.0041 0.0184

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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