Detailed information for compound 2075335

Basic information

Technical information
  • TDR Targets ID: 2075335
  • Name: 2-(5-bromo-2-ethoxyphenyl)pyrrolidine hydrobr omide
  • MW: 351.077 | Formula: C12H17Br2NO
  • H donors: 1 H acceptors: 0 LogP: 3.81 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1C1CCCN1)Br.Br
  • InChi: 1S/C12H16BrNO.BrH/c1-2-15-12-6-5-9(13)8-10(12)11-4-3-7-14-11;/h5-6,8,11,14H,2-4,7H2,1H3;1H
  • InChiKey: PQZIJNMDWGCOFP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(5-bromo-2-ethoxy-phenyl)pyrrolidine hydrobromide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0081 0.0683 0.0923
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.0289 0.0289
Brugia malayi mbt repeat family protein 0.005 0.0324 0.0438
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0289 0.0289
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0035 0.0225
Echinococcus granulosus raf serine:threonine protein kinase 0.0036 0.0168 0.0168
Echinococcus multilocularis protein kinase c iota type 0.0087 0.0749 0.0749
Schistosoma mansoni amine GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0051 0.0338 0.0338
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.0036 0.0168 0.0168
Leishmania major endonuclease G, putative 0.0058 0.0417 0.1094
Entamoeba histolytica Flap nuclease, putative 0.003 0.0102 0.0338
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis protein kinase c eta type 0.0036 0.0168 0.0168
Echinococcus granulosus N chimaerin 0.0036 0.0168 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0218 0.0294
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.0338 0.0457
Schistosoma mansoni serine/threonine protein kinase 0.0231 0.2397 0.2397
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0102 0.0338
Schistosoma mansoni hypothetical protein 0.0047 0.0289 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0218 0.0294
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0218 0.0218
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0251 0.0865
Loa Loa (eye worm) acetyltransferase 0.0317 0.3386 0.4575
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0593 0.2068
Onchocerca volvulus 0.0047 0.0289 0.0618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.0289 0.039
Onchocerca volvulus 0.0047 0.0289 0.0618
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.0289 0.0289
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0096 0.0856 0.0856
Brugia malayi RhoGAP domain containing protein 0.0036 0.0168 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Brugia malayi RE15519p 0.0047 0.0289 0.039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0218 0.0294
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0051 0.0338 0.0338
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Schistosoma mansoni cpg binding protein 0.0063 0.0475 0.0475
Echinococcus granulosus protein kinase c eta type 0.0036 0.0168 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0024 0.0036 0.0165
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.0289 0.0289
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0103 0.0753
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.0289 0.039
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.1282 0.1282
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0251 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.3762 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0218 0.0218
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0289 0.0289
Brugia malayi diacylglycerol kinase 0.0036 0.0168 0.0226
Brugia malayi polk-prov protein 0.0036 0.0164 0.0222
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni endonuclease related 0.0058 0.0417 0.0417
Schistosoma mansoni hypothetical protein 0.0306 0.326 0.326
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0251 0.0865
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.0289 0.0289
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0073 0.0593 0.0801
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.0289 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.018 0.018
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0446 0.1551
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0024 0.0036 0.0165
Schistosoma mansoni hypothetical protein 0.0024 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis Diacylglycerol kinase theta 0.0036 0.0168 0.0168
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.0165 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Toxoplasma gondii peptidylprolyl isomerase 0.0071 0.0573 0.4406
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0446 0.1172
Brugia malayi Flap endonuclease-1 0.003 0.0102 0.0137
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0096 0.0856 0.0856
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0072
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0324 0.0324
Echinococcus granulosus g protein coupled receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0324 0.0438
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0289 0.0289
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0268 0.0697
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0035 0.118
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi Ras association domain family 1 isoform A 0.0036 0.0168 0.0226
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0324 0.0324
Echinococcus multilocularis protein kinase c epsilon type 0.014 0.1358 0.1358
Echinococcus granulosus jumonji domain containing protein 0.013 0.125 0.125
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0035 0.0156
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0024 0.0036 0.0165
Schistosoma mansoni rac gtpase activating protein 0.0036 0.0168 0.0168
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.0165 0.0424
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Loa Loa (eye worm) MBCTL1 0.0056 0.0403 0.0544
Echinococcus granulosus serine:threonine protein kinase N2 0.0051 0.0338 0.0338
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.0289 0.0289
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0301 0.0301
Mycobacterium tuberculosis Conserved hypothetical protein 0.0184 0.1866 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0132 0.1265 1
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0446 0.2367
Schistosoma mansoni tar DNA-binding protein 0.0286 0.3031 0.3031
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0097 0.0868 0.0868
Echinococcus multilocularis tar DNA binding protein 0.0286 0.3031 0.3031
Loa Loa (eye worm) hypothetical protein 0.0096 0.0856 0.1156
Brugia malayi steroid hormone receptor 0.004 0.0218 0.0294
Brugia malayi Bromodomain containing protein 0.0101 0.0918 0.1241
Echinococcus granulosus g-protein coupled receptor 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0047 0.0289 0.0618
Brugia malayi RhoGEF domain containing protein 0.0036 0.0168 0.0226
Loa Loa (eye worm) RNA binding protein 0.0286 0.3031 0.4096
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0024 0.0036 0.0165
Brugia malayi Protein kinase domain containing protein 0.0051 0.0338 0.0457
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0746 0.0746
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0093 0.0824 0.6353
Mycobacterium leprae putative cytochrome p450 0.0024 0.0036 0.0014
Schistosoma mansoni hypothetical protein 0.0079 0.0659 0.0659
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0096 0.0856 0.0856
Brugia malayi Thrombospondin type 1 domain containing protein 0.0207 0.213 0.2877
Brugia malayi C1-like domain containing protein 0.0037 0.018 0.0243
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0746 0.1008
Echinococcus granulosus somatostatin receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi Cytochrome P450 family protein 0.0024 0.0036 0.0049
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0218 0.0218
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.0289 0.0289
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0006 0.0008
Echinococcus granulosus g protein coupled receptor 0.0047 0.0289 0.0289
Brugia malayi neuropeptide F receptor 0.0047 0.0289 0.039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Brugia malayi small heat shock protein 0.0668 0.7401 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0251 0.0865
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0218 0.0218
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0035 0.0352
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Echinococcus granulosus NDR protein kinase 0.0051 0.0338 0.0338
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0218 0.0218
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0165 0.0223
Onchocerca volvulus 0.0047 0.0289 0.0618
Schistosoma mansoni tar DNA-binding protein 0.0286 0.3031 0.3031
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0024 0.0036 0.0165
Brugia malayi larval opioid receptor 0.0047 0.0289 0.039
Giardia lamblia DINP protein human, muc B family 0.0042 0.0235 0.0807
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0024 0.0036 0.0165
Brugia malayi Serotonin receptor 0.0047 0.0289 0.039
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0218 0.0256
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0037 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0096 0.0856 0.1156
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0746 0.0746
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0199 0.134
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus protein kinase c iota type 0.0087 0.0749 0.0749
Echinococcus granulosus flap endonuclease 1 0.003 0.0102 0.0102
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0403 0.0544
Brugia malayi PHD-finger family protein 0.0094 0.0829 0.1121
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0218 0.0218
Onchocerca volvulus 0.0047 0.0289 0.0618
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0286 0.3031 0.4096
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0289 0.0289
Schistosoma mansoni tar DNA-binding protein 0.0286 0.3031 0.3031
Echinococcus multilocularis Endonuclease G 0.0058 0.0417 0.0417
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Schistosoma mansoni opsin-like receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0103 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0036 0.0168 0.0168
Echinococcus granulosus Endonuclease G 0.0058 0.0417 0.0417
Echinococcus granulosus serine:threonine protein kinase N2 0.0049 0.0317 0.0317
Brugia malayi Serotonin receptor 0.0047 0.0289 0.039
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0134 0.1293 0.1293
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0218 0.0294
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0289 0.0289
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.0011 0.0013
Brugia malayi GnHR receptor homolog 0.0047 0.0289 0.039
Brugia malayi acetyltransferase, GNAT family protein 0.0317 0.3386 0.4575
Leishmania major hypothetical protein, conserved 0.0026 0.0053 0.0126
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.0289 0.0289
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.0289 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Loa Loa (eye worm) zinc finger protein 0.0261 0.2743 0.3706
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) cytochrome P450 0.0024 0.0036 0.0049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0301 0.0407
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0218 0.0218
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0218 0.0294
Schistosoma mansoni inositol monophosphatase 0.0043 0.0251 0.0251
Plasmodium falciparum histone acetyltransferase GCN5 0.0085 0.0735 0.8851
Brugia malayi diacylglycerol kinase 0.0036 0.0168 0.0226
Brugia malayi Cytochrome P450 family protein 0.0045 0.0268 0.0362
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.0289 0.0289
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0102 0.0255
Trypanosoma brucei endonuclease G, putative 0.0058 0.0417 0.1094
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0576
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0024 0.0036 0.0165
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Schistosoma mansoni opsin-like receptor 0.0047 0.0289 0.0289
Brugia malayi Dopamine receptor protein 1 0.0047 0.0289 0.039
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0024 0.0036 0.0165
Onchocerca volvulus 0.0047 0.0289 0.0618
Trichomonas vaginalis bromodomain-containing protein, putative 0.0093 0.0824 0.2881
Echinococcus granulosus serotonin receptor 0.0047 0.0289 0.0289
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0024 0.0036 0.0082
Schistosoma mansoni ap endonuclease 0.0022 0.0006 0.0006
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0218 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.0289 0.0618
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0093 0.0824 0.993
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0218 0.0294
Schistosoma mansoni biogenic amine receptor 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0047 0.0289 0.0618
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0126
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0035 0.0077
Echinococcus granulosus neuropeptide receptor 0.0047 0.0289 0.0289
Brugia malayi protein kinase C3,putative 0.0037 0.018 0.0243
Echinococcus granulosus neuropeptide receptor 0.0047 0.0289 0.0289
Treponema pallidum fructose-bisphosphate aldolase 0.027 0.2845 1
Schistosoma mansoni adenoreceptor 0.0047 0.0289 0.0289
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.0289 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Trypanosoma brucei endonuclease G, putative 0.0058 0.0417 0.1094
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Echinococcus multilocularis neuropeptide receptor A26 0.0525 0.5767 0.5767
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0024 0.0036 0.0165
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0233 0.2428 0.2428
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0041 0.0228 0.0308
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1293 0.692
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0446 0.1172
Schistosoma mansoni jumonji domain containing protein 0.003 0.0103 0.0103
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.005 0.0325 0.1126
Schistosoma mansoni phd/f-box containing protein 0.003 0.0103 0.0103
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0053 0.0576
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0301 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0218 0.0294
Trypanosoma brucei unspecified product 0.0025 0.0038 0.0087
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.0289 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.0289 0.0289
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0103 0.0103
Brugia malayi mbt repeat family protein 0.005 0.0324 0.0438
Schistosoma mansoni diacylglycerol kinase theta 0.0036 0.0168 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0024 0.0036 0.0165
Schistosoma mansoni inositol monophosphatase 0.0043 0.0251 0.0251
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.0289 0.039
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0164 0.0422
Brugia malayi ORL1-like opioid receptor 0.0047 0.0289 0.039
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0268 0.0697
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0094 0.0829 0.0829
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0218 0.0294
Onchocerca volvulus 0.005 0.0324 0.0799
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0102 0.0255
Schistosoma mansoni hypothetical protein 0.0047 0.0289 0.0289
Echinococcus multilocularis jumonji domain containing protein 0.013 0.125 0.125
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0035 0.5
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0268 0.0697
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Echinococcus granulosus dna polymerase kappa 0.006 0.0446 0.0446
Brugia malayi Variant SH3 domain containing protein 0.0036 0.0168 0.0226
Entamoeba histolytica diacylglycerol kinase, putative 0.0036 0.0168 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Leishmania major hypothetical protein, conserved 0.003 0.0103 0.0258
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0107 0.0787
Echinococcus multilocularis serine:threonine protein kinase N2 0.0099 0.0886 0.0886
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Schistosoma mansoni myosin xvIII 0.0047 0.0289 0.0289
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0134 0.1293 0.692
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0307 0.3271 0.3271
Echinococcus granulosus expressed protein 0.0073 0.0593 0.0593
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.0289 0.0289
Schistosoma mansoni protein phosphatase 2C 0.003 0.0103 0.0103
Onchocerca volvulus 0.0063 0.0475 0.157
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0024 0.0036 0.0165
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.0289 0.039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Brugia malayi Zinc finger, C2H2 type family protein 0.0261 0.2743 0.3706
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0218 0.0294
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0289 0.0289
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.0094 0.0829 0.0829
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0338 0.0338
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0093 0.0824 0.2881
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0108 0.0272
Brugia malayi TAR-binding protein 0.0286 0.3031 0.4096
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0268 0.0362
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0103 0.0258
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0036 0.0168 0.0226
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0103 0.0753
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0024 0.0036 0.0165
Brugia malayi hypothetical protein 0.0076 0.0629 0.085
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0235 0.061
Schistosoma mansoni rotamase 0.0073 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.003 0.0103 0.0139
Onchocerca volvulus 0.0047 0.0289 0.0618
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0475 0.0642
Loa Loa (eye worm) AGC/PKN protein kinase 0.0051 0.0338 0.0457
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.0289 0.0289
Schistosoma mansoni histamine h1 receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0668 0.7401 1
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0251 0.0251
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0073 0.0593 0.0801
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0094 0.0829 0.6398
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0024 0.0036 0.0165
Echinococcus multilocularis jun protein 0.0097 0.0868 0.0868
Schistosoma mansoni diacylglycerol kinase theta 0.0036 0.0168 0.0168
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0289 0.0289
Brugia malayi G protein-coupled receptor 0.0047 0.0289 0.039
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0024 0.0036 0.0165
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0218 0.0294
Trypanosoma brucei DNA polymerase IV, putative 0.0054 0.0376 0.0987
Loa Loa (eye worm) hypothetical protein 0.0242 0.253 0.3418
Schistosoma mansoni hypothetical protein 0.0047 0.0289 0.0289
Leishmania major cytochrome p450-like protein 0.0045 0.0268 0.0697
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0289 0.0289
Entamoeba histolytica protein kinase, putative 0.0051 0.0338 0.117
Schistosoma mansoni neuropeptide receptor 0.0047 0.0289 0.0289
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0218 0.0218
Echinococcus granulosus sex peptide receptor 0.0047 0.0289 0.0289
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0218 0.0256
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.0165 0.0165
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0051 0.0338 0.0457
Echinococcus granulosus zinc finger transcription factor gli2 0.0261 0.2743 0.2743
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0289 0.0289
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0218 0.0218
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0199 0.1042
Echinococcus multilocularis dna polymerase kappa 0.006 0.0446 0.0446
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0024 0.0036 0.0165
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0035 0.0352
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0058 0.0417 0.3192
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0108 0.0272
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0446 0.1172
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.0289 0.0289
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1293 0.1293
Loa Loa (eye worm) hypothetical protein 0.0191 0.1948 0.2632
Echinococcus multilocularis flap endonuclease 1 0.003 0.0102 0.0102
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.0011 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0218 0.0294
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0338 0.0338
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0102 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0036 0.0168 0.0168
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0324 0.0324
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi putative neuropeptide receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0094 0.0829 0.1121
Plasmodium vivax hypothetical protein, conserved 0.0094 0.0829 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0049 0.0317 0.1096
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0218 0.0256
Schistosoma mansoni serine/threonine protein kinase 0.014 0.1358 0.1358
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0289 0.0289
Echinococcus multilocularis neuropeptide s receptor 0.0525 0.5767 0.5767
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.0289 0.0289
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0022 0.0011 0.0199
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Echinococcus multilocularis raf serine:threonine protein kinase 0.0036 0.0168 0.0168
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0081 0.0683 0.0683
Brugia malayi p70 ribosomal S6 kinase beta 0.0051 0.0338 0.0457
Echinococcus multilocularis orexin receptor type 2 0.0047 0.0289 0.0289
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0324 0.0324
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1293 0.692
Onchocerca volvulus 0.0041 0.0228 0.0308
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0144 0.0144
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0047 0.0289 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0024 0.0036 0.0165
Brugia malayi G-protein coupled receptor 0.0047 0.0289 0.039
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0289 0.0289
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0024 0.0036 0.0082
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0053 0.0126
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0058 0.0417 0.1094
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0022 0.0011 0.0013
Trypanosoma brucei unspecified product 0.0025 0.0038 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0218 0.0294
Toxoplasma gondii cytochrome p450 superfamily protein 0.0024 0.0036 0.0238
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis zinc finger transcription factor gli2 0.0261 0.2743 0.2743
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0006 0.0006
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.0289 0.039
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0024 0.0036 0.0165
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0006 0.0008
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0031 0.0107 0.027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0289 0.0289
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0006 0.0008
Onchocerca volvulus 0.0047 0.0289 0.0618
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.0289 0.0289
Brugia malayi AF-10 protein 0.0031 0.0107 0.0145
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0024 0.0036 0.0165
Plasmodium falciparum flap endonuclease 1 0.003 0.0102 0.1165
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0443 0.1163
Schistosoma mansoni jumonji domain containing protein 0.0244 0.2549 0.2549
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0103 0.0103
Schistosoma mansoni flap endonuclease-1 0.0027 0.0068 0.0068
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0022 0.0011 0.0013
Echinococcus granulosus ectonucleotide 0.0081 0.0683 0.0683
Schistosoma mansoni thyroid hormone receptor 0.004 0.0218 0.0218
Schistosoma mansoni opsin-like receptor 0.0047 0.0289 0.0289
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0071 0.0573 0.151
Brugia malayi AKH receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0096 0.0856 0.1156
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi cytochrome P450 0.0024 0.0036 0.0049
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0051 0.0338 0.0457
Echinococcus granulosus phd:f box containing protein 0.003 0.0103 0.0103
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0165 0.0424
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0165 0.0857
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0446 0.2367
Echinococcus granulosus histone acetyltransferase KAT2B 0.0308 0.3284 0.3284
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0289 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0301 0.0301
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0103 0.0139
Schistosoma mansoni cpg binding protein 0.0066 0.0516 0.0516
Loa Loa (eye worm) RasGEF domain-containing protein 0.0036 0.0168 0.0226
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0403 0.0403
Giardia lamblia PHD finger protein 15 0.0094 0.0829 0.2902
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0051 0.0338 0.0338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Echinococcus multilocularis geminin 0.0372 0.4022 0.4022
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0134 0.1293 0.3428
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0338 0.0338
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0268 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis Rac GTPase activating protein 1 0.0036 0.0168 0.0168
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0051 0.0338 0.0457
Brugia malayi hypothetical protein 0.0026 0.0053 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0218 0.0294
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0324 0.0799
Brugia malayi nuclear receptor NHR-88 0.004 0.0218 0.0294
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi RNA binding protein 0.0286 0.3031 0.4096
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0403 0.0403
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0307 0.3271 0.3271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Entamoeba histolytica acetyltransferase, GNAT family 0.0085 0.0735 0.2568
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0446 0.1172
Leishmania major cytochrome p450-like protein 0.0024 0.0036 0.0082
Entamoeba histolytica protein kinase, putative 0.0051 0.0338 0.117
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) TAR-binding protein 0.0286 0.3031 0.4096
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0746 0.0746
Brugia malayi RhoGAP domain containing protein 0.0036 0.0168 0.0226
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0218 0.0294
Loa Loa (eye worm) jmjC domain-containing protein 0.0117 0.1096 0.1481
Brugia malayi Dopamine receptor protein 2 0.0047 0.0289 0.039
Onchocerca volvulus 0.0047 0.0289 0.0618
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0132 0.1265 0.6768
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis serine threonine protein kinase 0.0195 0.1986 0.1986
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.0289 0.0289
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Echinococcus multilocularis unc 13 (munc13) 0.0041 0.0228 0.0228
Schistosoma mansoni serine/threonine kinase 0.0051 0.0338 0.0338
Echinococcus granulosus tar DNA binding protein 0.0286 0.3031 0.3031
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi PHD-finger family protein 0.0034 0.0148 0.02
Echinococcus multilocularis lysine specific demethylase 5A 0.0113 0.1055 0.1055
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0132 0.1265 0.6768
Leishmania major DNA polymerase kappa, putative 0.0042 0.0235 0.061
Loa Loa (eye worm) raf kinase 0.0036 0.0168 0.0226
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0301 0.0407
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0103 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0006 0.0006
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0024 0.0036 0.0165
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0034 0.0151 0.1762
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0235 0.061
Brugia malayi Hr1 repeat family protein 0.0051 0.0338 0.0457
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0058 0.0417 0.1094
Schistosoma mansoni nuclear hormone receptor 0.004 0.0218 0.0218
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0096 0.0856 0.0856
Schistosoma mansoni coup transcription factor 0.004 0.0218 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0327 0.0441
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0081 0.0683 0.0683
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0165 0.0223
Echinococcus multilocularis N chimaerin 0.0036 0.0168 0.0168
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0324 0.0324
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0058 0.0417 0.1094
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0289 0.0289
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0289 0.0289
Trypanosoma cruzi endonuclease G, putative 0.0058 0.0417 0.1094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.032 0.0835
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0071 0.0573 0.151
Schistosoma mansoni jumonji/arid domain-containing protein 0.0117 0.1096 0.1096
Schistosoma mansoni hypothetical protein 0.0895 1 1
Plasmodium vivax JmjC domain containing protein 0.003 0.0103 0.1177
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0151 0.1762
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0218 0.0218
Echinococcus multilocularis expressed protein 0.0403 0.4374 0.4374
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.0094 0.0837 0.1131
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0037 0.018 0.0243
Loa Loa (eye worm) hypothetical protein 0.0191 0.1948 0.2632
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0317 0.3386 0.3386
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Onchocerca volvulus Alhambra homolog 0.0094 0.0829 0.3374
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Schistosoma mansoni DNA polymerase eta 0.0036 0.0165 0.0165
Echinococcus granulosus neuropeptide receptor A26 0.0525 0.5767 0.5767
Echinococcus granulosus protein kinase C gamma type 0.0195 0.1986 0.1986
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0036 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0168 0.0168
Trichomonas vaginalis rotamase, putative 0.0073 0.0593 0.2068
Schistosoma mansoni jun-related protein 0.0079 0.0659 0.0659
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0037 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0372 0.4022 0.4022
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0218 0.0218
Echinococcus multilocularis sex peptide receptor 0.0047 0.0289 0.0289
Echinococcus granulosus Diacylglycerol kinase theta 0.0036 0.0168 0.0168
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0041 0.0228 0.0228
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0024 0.0036 0.0165
Entamoeba histolytica diacylglycerol kinase, putative 0.0036 0.0168 0.057
Toxoplasma gondii aldehyde dehydrogenase 0.0134 0.1293 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0036 0.0168 0.0226
Schistosoma mansoni unc-13 (munc13) 0.0041 0.0228 0.0228
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0289 0.039
Toxoplasma gondii PHD-finger domain-containing protein 0.0094 0.0829 0.6398
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0046 0.0286 0.0286
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0053 0.0369
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0446 0.1172
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.0289 0.0289
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0103 0.0258
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0102 0.0137
Brugia malayi Protein kinase c protein 2 0.0181 0.1828 0.247
Echinococcus granulosus Protein kinase C brain isozyme 0.0231 0.2397 0.2397
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0051 0.0338 0.0338
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.0175 0.1755 0.2371
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0036 0.0082
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0103 0.0103
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0097 0.0868 0.0868
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0218 0.0218
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0086 0.0746 0.295
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Schistosoma mansoni amine GPCR 0.0047 0.0289 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0006 0.0006
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.032 0.0835
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0843 0.9413 0.9413
Schistosoma mansoni atypical protein kinase C 0.0087 0.0749 0.0749
Schistosoma mansoni biogenic amine receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.0165 0.0223
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0093 0.0824 0.6353
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0006 0.0008
Brugia malayi Melatonin receptor type 1A 0.0047 0.0289 0.039
Brugia malayi protein kinase C II. 0.014 0.1358 0.1835
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0251 0.132
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0036 0.0168 0.0226
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0289 0.0289
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Loa Loa (eye worm) hypothetical protein 0.0227 0.2359 0.3188
Loa Loa (eye worm) hypothetical protein 0.0139 0.1344 0.1816
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0024 0.0036 0.0165
Trypanosoma brucei unspecified product 0.0054 0.0376 0.0987
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0403 0.0403
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0103 0.0139
Schistosoma mansoni vav2 0.0036 0.0168 0.0168
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0166 0.1652 0.4383
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0251 0.0865
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Brugia malayi Protein kinase domain containing protein 0.0051 0.0338 0.0457
Echinococcus multilocularis RNA directed DNA polymerase 0.014 0.1362 0.1362
Brugia malayi CXXC zinc finger family protein 0.0063 0.0475 0.0642
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0035 0.0102
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0324 0.0324
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0268 0.0362
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0251 0.0654
Brugia malayi bZIP transcription factor family protein 0.0097 0.0868 0.1172
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.032 0.0835
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi G-protein coupled receptor 0.0047 0.0289 0.039
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0403 0.0403
Schistosoma mansoni neuropeptide receptor 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0191 0.1948 0.9074
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0024 0.0036 0.0165
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0289 0.0289
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0289 0.0289
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0218 0.0294
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.0289 0.039
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.005 0.0324 0.0438
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0231 0.2397 0.2397
Entamoeba histolytica protein kinase, putative 0.0051 0.0338 0.117
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0024 0.0036 0.0165
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.0289 0.039
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.0165 0.0165
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0446 0.1551
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.0289 0.0289
Brugia malayi Protein kinase domain containing protein 0.0051 0.0338 0.0457
Echinococcus granulosus protein kinase c epsilon type 0.014 0.1358 0.1358
Brugia malayi follicle stimulating hormone receptor 0.0047 0.0289 0.039
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0024 0.0036 0.0165
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0251 0.0654
Trichomonas vaginalis rotamase, putative 0.0071 0.0573 0.1999
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.1652 0.4383
Echinococcus multilocularis PHD finger protein rhinoceros 0.0094 0.0829 0.0829
Echinococcus granulosus neuropeptide s receptor 0.0525 0.5767 0.5767
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Toxoplasma gondii diacylglycerol kinase, putative 0.0036 0.0168 0.1257
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0251 0.0654
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0251 0.0251
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.0338 0.0885
Plasmodium falciparum phd finger protein, putative 0.0094 0.0829 1
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.027 0.2845 1
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0096 0.0856 0.0856
Schistosoma mansoni hypothetical protein 0.007 0.0563 0.0563
Brugia malayi ecdysteroid receptor 0.004 0.0218 0.0294
Schistosoma mansoni protein kinase C 0.0041 0.0228 0.0228
Brugia malayi Inositol-1 0.0043 0.0251 0.034
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0096 0.0856 0.1156
Echinococcus multilocularis serotonin receptor 0.0047 0.0289 0.0289
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1293 0.692
Echinococcus granulosus geminin 0.0372 0.4022 0.4022
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0289 0.0289
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus RNA directed DNA polymerase 0.014 0.1362 0.1362
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0024 0.0036 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0338 0.117
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus cpg binding protein 0.0066 0.0516 0.0516
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0034 0.0148 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0035 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0218 0.0294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0218 0.0294
Brugia malayi jmjC domain containing protein 0.0307 0.3271 0.442
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0006 0.0006
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0218 0.0218
Echinococcus granulosus hypothetical protein 0.0047 0.0289 0.0289
Brugia malayi Cytochrome P450 family protein 0.0068 0.054 0.0729
Onchocerca volvulus 0.0047 0.0289 0.0618
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0035 0.0225
Loa Loa (eye worm) hypothetical protein 0.0056 0.0403 0.0544
Schistosoma mansoni jumonji/arid domain-containing protein 0.0117 0.1096 0.1096
Giardia lamblia Fructose-bisphosphate aldolase 0.027 0.2845 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0024 0.0036 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.0289 0.039
Echinococcus granulosus orexin receptor type 2 0.0047 0.0289 0.0289
Loa Loa (eye worm) PHD-finger family protein 0.0094 0.0829 0.1121
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0024 0.0036 0.0165
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0301 0.0301
Brugia malayi jmjC domain containing protein 0.003 0.0103 0.0139
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0235 0.1232
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.1652 0.4383
Loa Loa (eye worm) jmjC domain-containing protein 0.0194 0.1972 0.2665
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.0289 0.039
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0289 0.0289
Echinococcus multilocularis ectonucleotide 0.0081 0.0683 0.0683
Echinococcus multilocularis cpg binding protein 0.0066 0.0516 0.0516
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.0031 0.0107 0.0107
Echinococcus multilocularis allatostatin A receptor 0.0047 0.0289 0.0289
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Echinococcus granulosus endonuclease exonuclease phosphatase 0.02 0.2045 0.2045
Schistosoma mansoni neuropeptide receptor 0.0047 0.0289 0.0289
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.014 0.1362 0.1362
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0301 0.0301
Schistosoma mansoni cytochrome P450 0.0024 0.0036 0.0036
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0051 0.0338 0.0338
Brugia malayi jmjC domain containing protein 0.0117 0.1096 0.1481
Onchocerca volvulus 0.0096 0.0856 0.3507
Echinococcus multilocularis myotubularin protein 13 0.0036 0.0168 0.0168
Echinococcus multilocularis expressed protein 0.0073 0.0593 0.0593
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.0289 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.2416 0.2416
Brugia malayi sulfakinin receptor protein 0.0047 0.0289 0.039
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0006 0.0008
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0035 0.0156
Loa Loa (eye worm) cytochrome P450 family protein 0.0068 0.054 0.0729
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.0289 0.0289
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0103 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0218 0.0294
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0289 0.039
Leishmania major DNA polymerase eta, putative 0.0036 0.0165 0.0424
Trypanosoma brucei endonuclease G, putative 0.0058 0.0417 0.1094
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.0289 0.0289
Leishmania major cytochrome p450-like protein 0.0024 0.0036 0.0082
Giardia lamblia Histone acetyltransferase GCN5 0.0085 0.0735 0.2568
Brugia malayi RNA recognition motif domain containing protein 0.0286 0.3031 0.4096
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0024 0.0036 0.0082
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) inositol-1 0.0043 0.0251 0.034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0289 0.0289
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.0165 0.0165
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0324 0.0324
Brugia malayi Pleckstrin Homology Domain 0.0036 0.0168 0.0226
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.0289 0.0289
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.0165 0.0165
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0022 0.0011 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0301 0.0301
Echinococcus granulosus lysine specific demethylase 5A 0.0117 0.1096 0.1096
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0053 0.0126
Echinococcus granulosus g protein coupled receptor 0.0047 0.0289 0.0289
Echinococcus granulosus FTZ F1 alpha 0.004 0.0218 0.0218
Schistosoma mansoni tar DNA-binding protein 0.0286 0.3031 0.3031
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0289 0.0289
Onchocerca volvulus 0.0047 0.0289 0.0618
Schistosoma mansoni amine GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0051 0.0338 0.0338
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0031 0.0107 0.0787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0218 0.0294
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0446 0.1172
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.032 0.0835
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0161 0.1596 0.2157
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0218 0.0218
Brugia malayi endonuclease G, mitochondrial precursor 0.0058 0.0417 0.0563
Schistosoma mansoni unc-13 (munc13) 0.0041 0.0228 0.0228
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0102 0.1165
Echinococcus multilocularis serine:threonine protein kinase 38 0.0051 0.0338 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0164 0.0422
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0289 0.0289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0218 0.0218
Echinococcus multilocularis dna polymerase eta 0.0036 0.0165 0.0165
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0035 0.0156
Toxoplasma gondii hypothetical protein 0.0056 0.0402 0.3081
Echinococcus granulosus fmrfamide receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0218 0.0294
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0403 0.0403
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.0289 0.0289
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.0289 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0289 0.039
Brugia malayi jmjC domain containing protein 0.003 0.0103 0.0139
Onchocerca volvulus 0.0047 0.0289 0.0618
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0071 0.0573 0.1999
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.3762 1
Brugia malayi Dopamine receptor 0.0047 0.0289 0.039
Schistosoma mansoni hypothetical protein 0.0372 0.4022 0.4022
Echinococcus granulosus unc 13 munc13 0.0041 0.0228 0.0228
Onchocerca volvulus 0.0096 0.0856 0.3507
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Entamoeba histolytica hypothetical protein 0.0024 0.0035 0.0102
Brugia malayi Protein kinase domain containing protein 0.0037 0.018 0.0243
Trypanosoma brucei mitochondrial DNA polymerase beta 0.035 0.3762 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0093 0.0824 0.0824
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0037 0.018 0.0243
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0024 0.0036 0.0082
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0041 0.0228 0.0228
Schistosoma mansoni tar DNA-binding protein 0.0286 0.3031 0.3031
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0024 0.0036 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Schistosoma mansoni hypothetical protein 0.0207 0.213 0.213
Echinococcus granulosus PHD finger protein rhinoceros 0.0094 0.0829 0.0829
Trypanosoma cruzi endonuclease G, putative 0.0058 0.0417 0.1094
Echinococcus multilocularis 0.0024 0.0036 0.0036
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0024 0.0036 0.0165
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0251 0.0654
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0134 0.1293 0.1293
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0024 0.0036 0.0165
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0268 0.1407
Schistosoma mansoni hypothetical protein 0.0047 0.0289 0.0289
Brugia malayi jmjC domain containing protein 0.003 0.0103 0.0139
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0218 0.0294
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0024 0.0036 0.0165
Echinococcus granulosus myotubularin protein 13 0.0036 0.0168 0.0168
Onchocerca volvulus 0.0047 0.0289 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0165 0.0223
Onchocerca volvulus 0.0207 0.213 1
Echinococcus multilocularis somatostatin receptor 0.0047 0.0289 0.0289
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0103 0.1177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.0289 0.0289
Echinococcus granulosus expressed protein 0.0403 0.4374 0.4374
Entamoeba histolytica hypothetical protein 0.0036 0.0168 0.057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0289 0.0289
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0071 0.0573 0.151
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0218 0.0218
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0037 0.018 0.0243
Entamoeba histolytica protein kinase, putative 0.0051 0.0338 0.117
Onchocerca volvulus 0.0076 0.0629 0.2352
Loa Loa (eye worm) hypothetical protein 0.003 0.0103 0.0139
Loa Loa (eye worm) AGC/NDR protein kinase 0.0051 0.0338 0.0457
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0024 0.0036 0.0165
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0218 0.0218
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0218 0.0294
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0024 0.0036 0.0165
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0024 0.0036 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0289 0.0289
Schistosoma mansoni cpg binding protein 0.0066 0.0516 0.0516
Schistosoma mansoni neuropeptide receptor 0.0047 0.0289 0.0289
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1293 0.1293
Echinococcus granulosus peregrin 0.0101 0.0918 0.0918
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0251 0.1908
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0145 0.1417 0.1914
Echinococcus granulosus Rac GTPase activating protein 1 0.0036 0.0168 0.0168
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0218 0.0294
Echinococcus multilocularis serine:threonine protein kinase N2 0.0051 0.0338 0.0338
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.0289 0.039
Schistosoma mansoni thyroid hormone receptor 0.004 0.0218 0.0218
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0024 0.0036 0.0165
Toxoplasma gondii histone lysine methyltransferase SET1 0.0127 0.1208 0.9336
Schistosoma mansoni protein kinase C mu 0.0036 0.0168 0.0168
Schistosoma mansoni ap endonuclease 0.0022 0.0006 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0338 0.0338
Brugia malayi neuropeptide F receptor 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0191 0.1948 0.2632
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.0289 0.039
Echinococcus granulosus jun protein 0.0097 0.0868 0.0868
Brugia malayi hypothetical protein 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0086 0.0746 0.1008
Loa Loa (eye worm) hypothetical protein 0.004 0.0218 0.0294
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.027 0.2845 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Schistosoma mansoni protein kinase C mu 0.0037 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi Cytochrome P450 family protein 0.0045 0.0268 0.0362
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.0289 0.0289
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.0289 0.039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Onchocerca volvulus 0.0047 0.0289 0.0618
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.0289 0.0289
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.014 0.1358 0.1835
Trypanosoma brucei RNA helicase, putative 0.007 0.0563 0.1484
Mycobacterium leprae Conserved hypothetical protein 0.0024 0.0036 0.0014
Onchocerca volvulus 0.0047 0.0289 0.0618
Echinococcus multilocularis dnaJ subfamily B 0.0895 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0218 0.0218
Echinococcus multilocularis phd:f box containing protein 0.003 0.0103 0.0103
Brugia malayi jmjC domain containing protein 0.003 0.0103 0.0139
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.027 0.2845 1
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0207 0.213 0.2877
Echinococcus granulosus allatostatin A receptor 0.0047 0.0289 0.0289
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.0289 0.0289
Onchocerca volvulus 0.004 0.0218 0.0256
Mycobacterium ulcerans hypothetical protein 0.0184 0.1866 1
Leishmania major mitochondrial DNA polymerase beta 0.035 0.3762 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.0289 0.0289
Echinococcus granulosus cytochrome P450 2K1 0.0024 0.0036 0.0036
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0103 0.0258
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0036 0.0168 0.0168
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0053 0.0576
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0289 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0289 0.0289
Schistosoma mansoni biogenic amine receptor 0.0047 0.0289 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.018 0.018
Echinococcus multilocularis serotonin receptor 0.0047 0.0289 0.0289
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0102 0.0338
Schistosoma mansoni amine GPCR 0.0047 0.0289 0.0289
Echinococcus granulosus dna polymerase eta 0.0036 0.0165 0.0165
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0051 0.0338 0.0457
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0102 0.0745
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0031 0.0107 0.027
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.0289 0.0289
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0289 0.0289
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0047 0.0289 0.039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0218 0.0294
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0226
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.0289 0.0289
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0108 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0446 0.1172
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0222
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0071 0.0573 0.151
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0144 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0289 0.0289
Brugia malayi nuclear hormone receptor 0.004 0.0218 0.0294
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0317 0.3386 0.3386
Echinococcus multilocularis peregrin 0.0101 0.0918 0.0918
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0218 0.0218
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0289 0.0289
Toxoplasma gondii AGC kinase 0.0051 0.0338 0.2581
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.02 0.2045 0.2045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.