Detailed information for compound 2075370

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 175.182 | Formula: C7H13NO4
  • H donors: 3 H acceptors: 4 LogP: -1.81 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1[C@@H](O)[C@@H](CN1C(=O)C)O
  • InChi: 1S/C7H13NO4/c1-4(10)8-2-6(11)7(12)5(8)3-9/h5-7,9,11-12H,2-3H2,1H3/t5-,6-,7-/m1/s1
  • InChiKey: XDOMDUAGAGUPQX-FSDSQADBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0203 0.1299 0.1603
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0035 0.0034
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0035 0.0242
Mycobacterium tuberculosis Probable lipase LipD 0.0165 0.1029 0.1284
Schistosoma mansoni hypothetical protein 0.0494 0.3381 0.338
Echinococcus granulosus cpg binding protein 0.0047 0.0191 0.0189
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.1513 0.1606
Echinococcus multilocularis dna polymerase kappa 0.0155 0.0956 0.0955
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0259 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.0609 0.0751
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0095 0.0116
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0103 0.0108
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0188 0.1197 0.127
Echinococcus multilocularis cpg binding protein 0.0047 0.0191 0.0189
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.005 0.021 0.0209
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.005 0.021 0.0258
Leishmania major pyruvate kinase 0.0034 0.0095 0.0099
Trypanosoma brucei unspecified product 0.0066 0.0325 0.0344
Schistosoma mansoni phosphoglycerate kinase 0.0191 0.1216 0.1215
Echinococcus granulosus phosphoglycerate kinase 1 0.0191 0.1216 0.1215
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0046 0.018 0.0221
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0214 0.0231
Brugia malayi CHD4 protein 0.0025 0.0034 0.0041
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0609 0.0646
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0084 0.0452 0.3709
Brugia malayi beta-lactamase family protein 0.0165 0.1029 0.1269
Schistosoma mansoni methyl-cpg binding protein mbd 0.0095 0.0534 0.0532
Loa Loa (eye worm) hypothetical protein 0.0021 0.0001 0.00000028588
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0149 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0609 0.0608
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) PHD-finger family protein 0.0115 0.0677 0.0834
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0165 0.1029 0.1284
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1513 0.1638
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0149 0.0147
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0095 0.0101
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0127 0.076 0.0759
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0095 0.0116
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0147
Loa Loa (eye worm) RecQ helicase 0.0093 0.0515 0.0634
Onchocerca volvulus Phospholipase A2 homolog 0.0455 0.3104 0.3359
Echinococcus granulosus PHD finger protein rhinoceros 0.0127 0.076 0.0759
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0065 0.0064
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0149 0.0147
Schistosoma mansoni kinase 0.0054 0.0237 0.0236
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0103 0.0108
Echinococcus granulosus peregrin 0.0148 0.0909 0.0908
Echinococcus multilocularis phd:f box containing protein 0.0057 0.0259 0.0258
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0214 0.0231
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0046 0.018 0.0221
Echinococcus multilocularis peregrin 0.0148 0.0909 0.0908
Echinococcus granulosus lysine specific demethylase 6a 0.0057 0.0259 0.0258
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0434 0.295 0.8879
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Plasmodium falciparum pyruvate kinase 0.0034 0.0095 0.077
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0059 0.0276 0.0436
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0258
Mycobacterium ulcerans phosphoglycerate kinase 0.0191 0.1216 0.2386
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0024 0.0024 0.0024
Trichomonas vaginalis hypothetical protein 0.0021 0.0001 0.0001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0044 0.0163 0.02
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0633 0.4377 0.4649
Trichomonas vaginalis D-aminoacylase, putative 0.0165 0.1029 0.1114
Loa Loa (eye worm) MBCTL1 0.018 0.1139 0.1406
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1339 0.9413 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0059 0.0276 0.2259
Echinococcus granulosus jumonji domain containing 1A 0.0057 0.0259 0.0258
Schistosoma mansoni DNA polymerase eta 0.0125 0.0742 0.0741
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0165 0.1029 0.1998
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus chromobox protein 1 0.0078 0.0411 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0166 0.104 0.1039
Schistosoma mansoni hypothetical protein 0.0042 0.0149 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0166 0.104 0.7454
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0024 0.0024 0.016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus GTP binding nuclear protein Ran 0.0046 0.018 0.0179
Echinococcus granulosus snurportin 1 0.0666 0.4609 0.4608
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0104 0.0598 0.4914
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0298 0.0315
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0179 0.1131 0.113
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0191 0.1216 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0149 0.0147
Schistosoma mansoni methyl-cpg binding protein mbd 0.0095 0.0534 0.0532
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.01 0.0122
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0476 0.3253 0.3252
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis jumonji domain containing 1A 0.0057 0.0259 0.0258
Mycobacterium tuberculosis Conserved protein 0.0165 0.1029 0.1284
Brugia malayi jmjC domain containing protein 0.0057 0.0259 0.0319
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0332 0.0409
Echinococcus granulosus geminin 0.0958 0.6694 0.6693
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.1513 0.1512
Echinococcus granulosus phd:f box containing protein 0.0057 0.0259 0.0258
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.0538 0.0775
Leishmania major DNA polymerase eta, putative 0.0058 0.0269 0.0285
Loa Loa (eye worm) hypothetical protein 0.0061 0.0291 0.0358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0332 0.0352
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0455 0.3104 0.3832
Brugia malayi F/Y-rich N-terminus family protein 0.0069 0.0345 0.0424
Trichomonas vaginalis hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0332 0.0477
Onchocerca volvulus 0.0158 0.0983 0.1063
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Giardia lamblia Transcription regulatory protein SNF2 0.0021 0.0001 0.00000000021303
Trichomonas vaginalis DNA helicase recq, putative 0.0093 0.0515 0.0557
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0189 0.0205
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Giardia lamblia Histone acetyltransferase GCN5 0.0084 0.0449 0.0647
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0034 0.0033
Brugia malayi jmjC domain containing protein 0.0057 0.0259 0.0319
Entamoeba histolytica ankyrin repeat protein, putative 0.0021 0.0001 0.00000007144
Plasmodium vivax phosphoglycerate kinase, putative 0.0191 0.1216 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0042 0.0149 0.1061
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1513 0.1638
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Trypanosoma brucei phosphoglycerate kinase 0.007 0.0353 0.0374
Schistosoma mansoni zinc finger protein 0.0119 0.0703 0.0702
Plasmodium vivax thioredoxin reductase, putative 0.0171 0.1074 0.883
Echinococcus granulosus flap endonuclease 1 0.0029 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0022 0.0025
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0191 0.1216 0.872
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0269 0.0285
Onchocerca volvulus 0.1314 0.9236 1
Brugia malayi Phospholipase A2 family protein 0.0096 0.0537 0.0662
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0149 0.0157
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0233 0.1513 0.2144
Loa Loa (eye worm) bromodomain containing protein 0.0106 0.0612 0.0755
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0191 0.1216 0.1317
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0188 0.1197 0.127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0061 0.0291 0.029
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0034 0.0033
Giardia lamblia DINP protein human, muc B family 0.0111 0.0642 0.0925
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0155 0.0956 0.1036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0632 0.4365 0.4364
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0149 0.0213
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.0323 0.2162 0.2668
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1513 0.2182
Toxoplasma gondii histone lysine methyltransferase SET1 0.0093 0.0514 0.3681
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0165 0.1029 0.1284
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0633 0.4377 0.4649
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Brugia malayi mbt repeat family protein 0.0158 0.0983 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Toxoplasma gondii ABC1 family protein 0.0165 0.1029 0.7377
Loa Loa (eye worm) glutaminase 0.0637 0.4401 0.5434
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.013 0.0129
Loa Loa (eye worm) hypothetical protein 0.0062 0.0298 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.014 0.0147
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0125 0.0742 0.0741
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0065 0.0068
Loa Loa (eye worm) ATP-dependent DNA helicase 0.005 0.021 0.0258
Toxoplasma gondii PHD-finger domain-containing protein 0.0127 0.076 0.5448
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0046 0.018 0.1285
Loa Loa (eye worm) hypothetical protein 0.0057 0.0259 0.0319
Echinococcus granulosus Peptidase C54 0.0061 0.0291 0.029
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0301 0.184
Brugia malayi 6-phosphofructokinase 0.0233 0.1513 0.1867
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0191 0.1216 0.1291
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.014 0.0152
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0609 0.0877
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0191 0.1216 0.1291
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0024 0.0024 0.0024
Mycobacterium ulcerans hypothetical protein 0.0165 0.1029 0.1998
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0429 0.0455
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0104 0.0598 0.4285
Mycobacterium tuberculosis Conserved protein 0.0165 0.1029 0.1284
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0059 0.0276 0.0249
Schistosoma mansoni hypothetical protein 0.097 0.6782 0.6782
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0165 0.1029 0.1284
Brugia malayi Flap endonuclease-1 0.0029 0.0061 0.0074
Leishmania major DNA polymerase kappa, putative 0.003 0.0065 0.0068
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis dna polymerase eta 0.0125 0.0742 0.0741
Plasmodium vivax basic transcription factor 3b, putative 0.0077 0.0401 0.329
Trichomonas vaginalis glutathione reductase, putative 0.0059 0.0276 0.0299
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Loa Loa (eye worm) hypothetical protein 0.0191 0.1216 0.15
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0103 0.0108
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0171 0.1074 0.1346
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0259 0.0319
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Mycobacterium ulcerans lipase LipD 0.0165 0.1029 0.1998
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0434 0.295 0.3925
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) BRM protein 0.0021 0.0001 0.00000000018232
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0214 0.0226
Toxoplasma gondii HEAT repeat-containing protein 0.0062 0.0298 0.213
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0484 0.0512
Echinococcus multilocularis flap endonuclease 1 0.0029 0.0061 0.006
Echinococcus granulosus SAM and MBT domain containing protein 0.0158 0.0983 0.0982
Echinococcus multilocularis lysine specific demethylase 6a 0.0057 0.0259 0.0258
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0025 0.0028 0.022
Schistosoma mansoni zinc finger protein 0.0086 0.0464 0.0462
Schistosoma mansoni cpg binding protein 0.0035 0.01 0.0099
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0165 0.0179
Loa Loa (eye worm) phosphofructokinase 0.0233 0.1513 0.1867
Echinococcus multilocularis phosphoglycerate kinase 1 0.0191 0.1216 0.1215
Echinococcus multilocularis importin subunit beta 1 0.0062 0.0298 0.0297
Trichomonas vaginalis mercuric reductase, putative 0.0059 0.0276 0.0299
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Toxoplasma gondii 6-phosphofructokinase 0.0063 0.0301 0.2152
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0095 0.0099
Mycobacterium tuberculosis Probable lipase LipE 0.0165 0.1029 0.1284
Entamoeba histolytica peptidase, C54 family 0.0024 0.0024 0.0032
Echinococcus granulosus fetal alzheimer antigen falz 0.0128 0.0767 0.0766
Plasmodium falciparum thioredoxin reductase 0.0059 0.0276 0.2259
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0095 0.0116
Echinococcus granulosus pyruvate kinase 0.0034 0.0095 0.0094
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0057 0.0259 0.0258
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0191 0.1216 0.1317
Schistosoma mansoni phd/f-box containing protein 0.0057 0.0259 0.0258
Schistosoma mansoni transcription factor btf3 0.0077 0.0401 0.04
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0301 0.2468
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0061 0.0291 0.0315
Brugia malayi Heterochromatin protein 1 0.0078 0.0411 0.0506
Echinococcus granulosus ATP dependent DNA helicase Q5 0.005 0.021 0.0209
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0165 0.0179
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.014 0.0147
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0147
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0059 0.0273 0.0289
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0059 0.0276 0.197
Schistosoma mansoni jumonji domain containing protein 0.0391 0.2642 0.2641
Plasmodium vivax hypothetical protein, conserved 0.0127 0.076 0.6247
Schistosoma mansoni ap endonuclease 0.004 0.014 0.0139
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0065 0.0068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0158 0.0983 0.0982
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0063 0.0301 0.0433
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0022 0.0025
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0301 0.2468
Trypanosoma cruzi DNA polymerase eta, putative 0.0125 0.0742 0.0787
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0059 0.0276 0.0292
Echinococcus granulosus jumonji domain containing protein 0.0177 0.1116 0.1115
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0029 0.0061 0.0064
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0059 0.0276 0.0292
Schistosoma mansoni hypothetical protein 0.0115 0.0677 0.0675
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Plasmodium falciparum thioredoxin reductase 0.0171 0.1074 0.883
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0103 0.0108
Plasmodium vivax 6-phosphofructokinase, putative 0.0063 0.0301 0.2468
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0063 0.0301 0.184
Brugia malayi polk-prov protein 0.0088 0.0484 0.0596
Trypanosoma brucei trypanothione reductase 0.0171 0.1074 0.114
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0095 0.0103
Mycobacterium tuberculosis Probable reductase 0.039 0.2639 0.3497
Plasmodium falciparum phosphoglycerate kinase 0.0191 0.1216 1
Brugia malayi Pre-SET motif family protein 0.0166 0.104 0.1283
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.018 0.1139 0.1138
Plasmodium vivax glutathione reductase, putative 0.0171 0.1074 0.883
Brugia malayi PHD-finger family protein 0.0149 0.0916 0.113
Trypanosoma brucei DNA polymerase eta, putative 0.0125 0.0742 0.0787
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0945 0.6604 0.6603
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0065 0.0068
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0104 0.0598 0.0597
Loa Loa (eye worm) hypothetical protein 0.0215 0.1385 0.1709
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0227 0.0246
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.014 0.0171
Entamoeba histolytica phosphoglycerate kinase, putative 0.0191 0.1216 0.1753
Brugia malayi N-terminal motif family protein 0.0203 0.1299 0.1603
Schistosoma mansoni hypothetical protein 0.0666 0.4609 0.4608
Loa Loa (eye worm) glutaminase 2 0.0637 0.4401 0.5434
Mycobacterium tuberculosis Probable hydrolase 0.0165 0.1029 0.1284
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.1513 0.1867
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0262 0.1721 0.172
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.0609 0.0608
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0538 0.0609
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0956 0.1848
Brugia malayi Phosphoglycerate kinase 0.0191 0.1216 0.15
Leishmania major DNA damage repair protein, putative 0.003 0.0065 0.0068
Entamoeba histolytica peptidase, C54 family 0.0024 0.0024 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis 6 phosphofructokinase 0.0233 0.1513 0.1512
Echinococcus granulosus 6 phosphofructokinase 0.0233 0.1513 0.1512
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0609 0.0646
Plasmodium vivax flap endonuclease 1, putative 0.0029 0.0061 0.0493
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0046 0.018 0.1474
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0063 0.0301 0.2468
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0128 0.0767 0.0766
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0332 0.0409
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0111 0.0642 0.0752
Schistosoma mansoni DNA helicase recq5 0.005 0.021 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0111 0.0642 0.0681
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0411 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trypanosoma brucei phosphoglycerate kinase 0.0191 0.1216 0.1291
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Mycobacterium ulcerans esterase/lipase LipP 0.0165 0.1029 0.1998
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0165 0.1029 0.1028
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0065 0.0527
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0029 0.0061 0.0429
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.007 0.035 0.0349
Echinococcus granulosus beta LACTamase domain containing family member 0.0165 0.1029 0.1028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Echinococcus granulosus transcription factor btf3 0.0077 0.0401 0.04
Echinococcus granulosus pyruvate kinase 0.0034 0.0095 0.0094
Echinococcus multilocularis beta LACTamase domain containing family member 0.0165 0.1029 0.1028
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.005 0.021 0.1501
Entamoeba histolytica Ran family GTPase 0.0046 0.018 0.0258
Schistosoma mansoni hypothetical protein 0.0958 0.6694 0.6693
Echinococcus granulosus global transcription activator snf2l2 0.0021 0.0001 0.00000000014763
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0059 0.0276 0.0292
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1513 0.1638
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.014 0.114
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.0609 0.0608
Loa Loa (eye worm) hypothetical protein 0.0158 0.0983 0.1212
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0029 0.0061 0.0064
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0332 0.0331
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Brugia malayi Peptidase family C54 containing protein 0.0061 0.0291 0.0358
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0158 0.0983 0.1063
Giardia lamblia Phosphoglycerate kinase 0.0191 0.1216 0.1753
Mycobacterium ulcerans glutaminase 0.0637 0.4401 0.8989
Leishmania major hypothetical protein, conserved 0.0086 0.0464 0.0491
Echinococcus multilocularis snurportin 1 0.0666 0.4609 0.4608
Toxoplasma gondii exonuclease III APE 0.004 0.014 0.0994
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0429 0.0455
Trichomonas vaginalis ap endonuclease, putative 0.004 0.014 0.0151
Echinococcus multilocularis histone acetyltransferase MYST2 0.018 0.1139 0.1138
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0061 0.0291 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis DNA polymerase eta, putative 0.0155 0.0956 0.1036
Echinococcus multilocularis jumonji domain containing protein 0.0177 0.1116 0.1115
Echinococcus multilocularis cysteine protease atg4b 0.0061 0.0291 0.029
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0095 0.0099
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0063 0.0301 0.0386
Loa Loa (eye worm) glutathione reductase 0.0171 0.1074 0.1325
Trypanosoma brucei phosphoglycerate kinase 0.0191 0.1216 0.1291
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0001 0.00000040749
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0059 0.0276 0.2259
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0149 0.0157
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0095 0.0103
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.014 0.0147
Brugia malayi chromobox protein homolog 3 0.0044 0.0165 0.0203
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0059 0.0276 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0705 0.4888 1
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0065 0.0068
Echinococcus multilocularis chromobox protein 1 0.0078 0.0411 0.0409
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0095 0.0672
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0128 0.0767 0.0766
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0484 0.331 0.6728
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0103 0.0102
Schistosoma mansoni importin beta-1 0.0062 0.0298 0.0297
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0095 0.077
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0046 0.018 0.0179
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1339 0.9413 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0084 0.0449 0.0647
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0275
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.0276 0.1263
Schistosoma mansoni cpg binding protein 0.0047 0.0191 0.0189
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0434 0.295 0.3925
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0103 0.0108
Brugia malayi BRM protein 0.0021 0.0001 0.00000000018232
Brugia malayi Pre-SET motif family protein 0.1154 0.8097 1
Brugia malayi CXXC zinc finger family protein 0.0035 0.01 0.0122
Echinococcus multilocularis SAM and MBT domain containing protein 0.0158 0.0983 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0074 0.008
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0401 0.0425
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0436
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0484 0.331 0.442
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.005 0.021 0.1722
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0095 0.0099
Echinococcus granulosus methyl CpG binding domain protein 2 0.0095 0.0534 0.0532
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.0538 0.0663
Entamoeba histolytica hypothetical protein 0.0051 0.0214 0.0307
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0095 0.0116
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.018 0.1139 0.1406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0059 0.0273 0.0289
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.0538 0.0537
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.014 0.0147
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Brugia malayi PHD-finger family protein 0.0054 0.024 0.0294
Loa Loa (eye worm) hypothetical protein 0.018 0.1139 0.1406
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Schistosoma mansoni chromobox protein 0.0078 0.0411 0.0409
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0292
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0058 0.0269 0.1925
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0191 0.1216 0.872
Toxoplasma gondii bromodomain-containing protein 0.0021 0.0001 0.00000035532
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei ISWI complex protein 0.0086 0.0464 0.0491
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0165 0.1029 0.846
Toxoplasma gondii thioredoxin reductase 0.0171 0.1074 0.77
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0065 0.0068
Schistosoma mansoni ran 0.0046 0.018 0.0179
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0046 0.018 0.1474
Schistosoma mansoni ap endonuclease 0.004 0.014 0.0139
Plasmodium falciparum bromodomain protein 1 0.0021 0.0001 0.00000040749
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0149 0.0161
Schistosoma mansoni helicase 0.0021 0.0001 0.00000000014763
Giardia lamblia Kinase, PLK 0.0106 0.0609 0.0877
Entamoeba histolytica peptidase, C54 family 0.0061 0.0291 0.0418
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.0276 0.0292
Plasmodium vivax JmjC domain containing protein 0.0057 0.0259 0.2125
Trichomonas vaginalis DNA helicase recq, putative 0.0059 0.0273 0.0296
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0476 0.3253 0.3252
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0061 0.0291 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Schistosoma mansoni chromobox protein 0.0078 0.0411 0.0409
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0058 0.0269 0.1925
Echinococcus granulosus zinc finger protein 0.0119 0.0703 0.0702
Loa Loa (eye worm) hypothetical protein 0.0096 0.0537 0.0662
Trichomonas vaginalis DNA helicase recq1, putative 0.0093 0.0515 0.0557
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Brugia malayi glutaminase DH11.1 0.0637 0.4401 0.5434
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0057 0.0259 0.1853
Loa Loa (eye worm) hypothetical protein 0.0034 0.0098 0.0119
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0001 0.0001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0226 0.1469 0.1468
Trypanosoma brucei polo-like protein kinase 0.0106 0.0609 0.0646
Plasmodium falciparum flap endonuclease 1 0.0029 0.0061 0.0493
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0411 0.0445
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0034 0.0041
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0111 0.0642 0.0681
Entamoeba histolytica recQ family DNA helicase 0.0026 0.0035 0.0049
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.018 0.019
Giardia lamblia NADH oxidase lateral transfer candidate 0.0059 0.0276 0.0396
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0061 0.0291 0.0308
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.005 0.021 0.0209
Mycobacterium ulcerans beta-lactamase 0.0165 0.1029 0.1998
Trichomonas vaginalis lymphoid specific helicase, putative 0.0021 0.0001 0.0001
Schistosoma mansoni glutaminase 0.0637 0.4401 0.44
Leishmania major trypanothione reductase 0.0171 0.1074 0.114
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0158 0.0983 0.0982
Plasmodium falciparum histone acetyltransferase GCN5 0.0084 0.0449 0.3689
Trypanosoma brucei importin beta-1 subunit, putative 0.0062 0.0298 0.0315
Plasmodium vivax SET domain containing protein 0.0028 0.005 0.0402
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.014 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0165 0.1029 0.1114
Loa Loa (eye worm) hypothetical protein 0.0054 0.024 0.0294
Mycobacterium tuberculosis Probable oxidoreductase 0.0434 0.295 0.3925
Schistosoma mansoni protein phosphatase 2C 0.0057 0.0259 0.0258
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.0276 0.1263
Trypanosoma cruzi hypothetical protein, conserved 0.0165 0.1029 0.1092
Leishmania major phosphoglycerate kinase B, cytosolic 0.0191 0.1216 0.1291
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0065 0.0527
Schistosoma mansoni jumonji/arid domain-containing protein 0.0226 0.1469 0.1468
Leishmania major DNA polymerase eta, putative 0.0125 0.0742 0.0787
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.0538 0.0537
Brugia malayi Importin beta-1 subunit 0.0062 0.0298 0.0366
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0103 0.0731
Trichomonas vaginalis bromodomain-containing protein, putative 0.0104 0.0598 0.0648
Loa Loa (eye worm) hypothetical protein 0.0234 0.1523 0.1879
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.039 0.2639 0.3497
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0059 0.0276 0.2259
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0059 0.0276 0.0292
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.014 0.0154
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0059 0.0276 0.2264
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0189 0.0203
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0021 0.0001 0.0000000010595
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0233 0.1513 0.4411
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus polycomb protein SCMH1 0.0158 0.0983 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Leishmania major GTP-binding protein, putative 0.0046 0.018 0.019
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0188 0.1197 0.127
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.039 0.2639 0.3497
Trypanosoma cruzi transcription factor btf3, putative 0.0077 0.0401 0.0425
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0254 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis glutaminase, putative 0.0637 0.4401 0.4765
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0149 0.0182
Schistosoma mansoni pyruvate kinase 0.0034 0.0095 0.0094
Onchocerca volvulus 0.0179 0.1131 0.1223
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Leishmania major pyruvate kinase 0.0034 0.0095 0.0099
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Treponema pallidum phosphoglycerate kinase 0.0191 0.1216 0.1713
Loa Loa (eye worm) hypothetical protein 0.0041 0.0149 0.0182
Giardia lamblia Fructose-bisphosphate aldolase 0.0991 0.6931 1
Treponema pallidum fructose-bisphosphate aldolase 0.0991 0.6931 1
Leishmania major hypothetical protein, conserved 0.0057 0.0259 0.0274
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0165 0.1029 0.1269
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.0538 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0066 0.0325 0.0344
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0095 0.0534 0.0532
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0057 0.0259 0.1853
Trypanosoma cruzi trypanothione reductase, putative 0.0059 0.0276 0.0292
Loa Loa (eye worm) mbt repeat family protein 0.0158 0.0983 0.1212
Brugia malayi translation initiation factor 4E 0.0035 0.0103 0.0126
Brugia malayi jmjC domain containing protein 0.0057 0.0259 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0956 0.1015
Schistosoma mansoni bromodomain containing protein 0.0033 0.0092 0.009
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0112
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0538 0.0663
Giardia lamblia DNA damage repair protein 0.003 0.0065 0.0092
Loa Loa (eye worm) hypothetical protein 0.0125 0.0742 0.0915
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0042 0.0149 0.0157
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0248 0.1624 0.2005
Echinococcus multilocularis polycomb protein SCMH1 0.0158 0.0983 0.0982
Brugia malayi beta-NAC-like protein 0.0077 0.0401 0.0494
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0149 0.0157
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Brugia malayi beta-lactamase 0.0165 0.1029 0.1269
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.014 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0476 0.3253 0.4016
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0149 0.0157
Echinococcus granulosus thioredoxin glutathione reductase 0.0173 0.1086 0.1084
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0201 0.1288 0.1287
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0292
Brugia malayi acetyltransferase, GNAT family protein 0.0323 0.2162 0.2668
Onchocerca volvulus Alhambra homolog 0.0127 0.076 0.0822
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0034 0.0033
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0229 0.1491 0.1583
Brugia malayi Bromodomain containing protein 0.0148 0.0909 0.1121
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.014 0.0062
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0332 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0074 0.008
Loa Loa (eye worm) hypothetical protein 0.0235 0.1534 0.1893
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0046 0.018 0.0258
Echinococcus multilocularis lysine specific demethylase 5A 0.0214 0.1379 0.1377
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0233 0.1513 0.195
Loa Loa (eye worm) hypothetical protein 0.0057 0.0259 0.0319
Loa Loa (eye worm) beta-lactamase 0.0165 0.1029 0.1269
Giardia lamblia Sgs1 DNA helicase, putative 0.005 0.021 0.0302
Trypanosoma brucei hypothetical protein, conserved 0.0165 0.1029 0.1092
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.014 0.114
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0095 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Brugia malayi PHD-finger family protein 0.0127 0.076 0.0937
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei unspecified product 0.014 0.0853 0.0905
Plasmodium vivax SET domain protein, putative 0.0166 0.104 0.8548
Echinococcus multilocularis pyruvate kinase 0.0034 0.0095 0.0094
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0149 0.0147
Trichomonas vaginalis penicillin-binding protein, putative 0.0165 0.1029 0.1114
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0063 0.0301 0.2152
Leishmania major basic transcription factor 3a, putative 0.0077 0.0401 0.0425
Echinococcus multilocularis pyruvate kinase 0.0027 0.0044 0.0043
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1154 0.8097 1
Echinococcus granulosus JmjC domain containing protein 4 0.0057 0.0259 0.0258
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0259 0.0319
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis bloom syndrome protein 0.0093 0.0515 0.0514
Mycobacterium tuberculosis Putative ferredoxin reductase 0.039 0.2639 0.3497
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0024 0.0024 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.008 0.0421 0.042
Trichomonas vaginalis flap endonuclease-1, putative 0.0029 0.0061 0.0066
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase 0.039 0.2639 0.3497
Toxoplasma gondii PHD-finger domain-containing protein 0.0127 0.076 0.5448
Brugia malayi Phosphoglycerate kinase 0.007 0.0353 0.0434
Toxoplasma gondii hypothetical protein 0.0216 0.1395 1
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0103 0.0112
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Echinococcus granulosus transcription factor Dp 1 0.0039 0.013 0.0129
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Brugia malayi ATPase, AAA family protein 0.0021 0.0001 0.00000028588
Mycobacterium leprae Probable lipase LipE 0.0165 0.1029 0.2905
Plasmodium falciparum cysteine protease ATG4, putative 0.0024 0.0024 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0165 0.1029 0.1092
Echinococcus multilocularis transcription factor btf3 0.0077 0.0401 0.04
Entamoeba histolytica peptidase, C54 family 0.0024 0.0024 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0401 0.0434
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.014 0.02
Giardia lamblia Pyruvate kinase 0.0034 0.0095 0.0135
Treponema pallidum NADH oxidase 0.0059 0.0276 0.0349
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.005 0.021 0.1501
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0125 0.0742 0.0915
Loa Loa (eye worm) flap endonuclease-1 0.0029 0.0061 0.0074
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0057 0.0259 0.0274
Onchocerca volvulus Phospholipase A2 homolog 0.0096 0.0537 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0095 0.0061
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0059 0.0276 0.2259
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0065 0.0068
Echinococcus multilocularis JmjC domain containing protein 4 0.0057 0.0259 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0401 0.0434
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0484 0.0596
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0991 0.6931 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0301 0.2005 0.2004
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0149 0.0147
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.0538 0.0537
Trypanosoma cruzi ISWI complex protein 0.0086 0.0464 0.0491
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.039 0.2639 0.7912
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.3381 0.338
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0149 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0227 0.0246
Schistosoma mansoni microtubule-associated protein tau 0.1421 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0061 0.0291 0.0315
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0233 0.1513 0.1606
Trichomonas vaginalis D-aminoacylase, putative 0.0165 0.1029 0.1114
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Echinococcus granulosus bloom syndrome protein 0.0093 0.0515 0.0514
Plasmodium falciparum importin beta, putative 0.0062 0.0298 0.2442
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.0276 0.0292
Schistosoma mansoni cpg binding protein 0.0047 0.0191 0.0189
Entamoeba histolytica transcription factor BTF3, putative 0.0077 0.0401 0.0577
Onchocerca volvulus 0.0034 0.0098 0.0104
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0332 0.0331
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0332 0.0352
Onchocerca volvulus 0.0165 0.1029 0.1113
Brugia malayi jmjC domain containing protein 0.0226 0.1469 0.1813
Echinococcus multilocularis microtubule associated protein 2 0.1421 1 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.0609 0.0751
Brugia malayi jmjC domain containing protein 0.0057 0.0259 0.0319
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0159 0.0991 0.099
Loa Loa (eye worm) ICD-1 protein 0.0077 0.0401 0.0494
Leishmania major importin beta-1 subunit, putative 0.0051 0.0214 0.0226
Brugia malayi mbt repeat family protein 0.0158 0.0983 0.1212
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.0609 0.0658
Giardia lamblia Flap structure-specific endonuclease 0.0029 0.0061 0.0086
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0065 0.0068
Plasmodium falciparum glutathione reductase 0.0171 0.1074 0.883
Leishmania major DNA polymerase kappa, putative 0.0111 0.0642 0.0681
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0095 0.0101
Plasmodium falciparum phd finger protein, putative 0.0127 0.076 0.6247
Leishmania major phosphoglycerate kinase C, glycosomal 0.0191 0.1216 0.1291
Loa Loa (eye worm) hypothetical protein 0.0034 0.0095 0.0116
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0158 0.0983 0.0982
Echinococcus multilocularis PHD finger protein rhinoceros 0.0127 0.076 0.0759
Brugia malayi AF-10 protein 0.0042 0.0149 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.0165 0.1029 0.1114
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0104 0.0598 0.4285
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0035 0.0036
Schistosoma mansoni 6-phosphofructokinase 0.0233 0.1513 0.1512
Loa Loa (eye worm) hypothetical protein 0.0044 0.0165 0.0203
Brugia malayi Bromodomain containing protein 0.0222 0.1437 0.1773
Echinococcus multilocularis Peptidase C54 0.0061 0.0291 0.029
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0332 0.0352
Echinococcus multilocularis global transcription activator snf2l2 0.0021 0.0001 0.00000000014763
Mycobacterium tuberculosis Conserved hypothetical protein 0.0705 0.4888 0.659
Schistosoma mansoni hypothetical protein 0.0127 0.076 0.0759
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0149 0.0147
Schistosoma mansoni phosphoglycerate kinase 0.0191 0.1216 0.1215
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0149 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0088 0.0484 0.0512
Schistosoma mansoni bromodomain containing protein 0.0363 0.2449 0.2448
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0411 0.0506
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1513 0.2182
Schistosoma mansoni DNA helicase recq1 0.005 0.021 0.0209
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Echinococcus granulosus lysine specific demethylase 5A 0.0226 0.1469 0.1468
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.014 0.02
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0259 0.0258
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0065 0.0068
Brugia malayi Thioredoxin reductase 0.0171 0.1074 0.1325
Echinococcus granulosus cysteine protease atg4b 0.0061 0.0291 0.029
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0666 0.4609 0.5691
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0165 0.1029 0.1269
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Brugia malayi glutathione reductase 0.0171 0.1074 0.1325
Echinococcus multilocularis chromobox protein 1 0.0078 0.0411 0.0409
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Schistosoma mansoni hypothetical protein 0.0958 0.6694 0.6693
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0061 0.0291 0.0315
Schistosoma mansoni autophagin-1 (C54 family) 0.0061 0.0291 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0401 0.0434
Schistosoma mansoni ran 0.0046 0.018 0.0179
Trichomonas vaginalis phosphofructokinase, putative 0.0233 0.1513 0.1638
Brugia malayi RNA, U transporter 1 0.0177 0.1119 0.1381
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0275
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0061 0.0291 0.0308
Schistosoma mansoni flap endonuclease-1 0.0026 0.0041 0.004
Echinococcus multilocularis thioredoxin glutathione reductase 0.0173 0.1086 0.1084
Leishmania major mitochondrial DNA polymerase beta 0.1339 0.9413 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0059 0.0276 0.0436
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.0609 0.0646
Entamoeba histolytica recQ family helicase, putative 0.0059 0.0273 0.0393
Loa Loa (eye worm) thioredoxin reductase 0.0171 0.1074 0.1325
Loa Loa (eye worm) hypothetical protein 0.0127 0.076 0.0937
Entamoeba histolytica hypothetical protein 0.0077 0.0401 0.0577
Onchocerca volvulus 0.0035 0.01 0.0107
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0201 0.1288 0.1287
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0262 0.1721 0.172
Brugia malayi Bromodomain containing protein 0.0429 0.2917 0.3601
Trypanosoma brucei DNA polymerase IV, putative 0.0155 0.0956 0.1015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0262 0.1721 0.172
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Plasmodium falciparum JmjC domain-containing protein, putative 0.0057 0.0259 0.2125
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0353 0.0374
Mycobacterium tuberculosis Probable esterase LipL 0.0165 0.1029 0.1284
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0189 0.0205
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0063 0.0301 0.0433
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.018 0.1139 0.1138
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0149 0.0161
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0095 0.0099
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0029 0.0061 0.0064
Loa Loa (eye worm) 6-phosphofructokinase 0.0233 0.1513 0.1867
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0042 0.0149 0.0157
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0035 0.0036
Schistosoma mansoni blooms syndrome DNA helicase 0.0067 0.0332 0.0331
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0095 0.0101
Schistosoma mansoni pyruvate kinase 0.0034 0.0095 0.0094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0166 0.104 0.1039
Entamoeba histolytica Flap nuclease, putative 0.0029 0.0061 0.0086
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0028 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0343 0.2306 0.2305
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1339 0.9413 1
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0022 0.0029
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0484 0.331 1
Plasmodium falciparum glutathione reductase 0.0059 0.0276 0.2259
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0991 0.6931 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.1154 0.1424
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0061 0.0291 0.029
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0323 0.2162 0.216
Schistosoma mansoni myelin transcription factor 1 myt1 0.018 0.1139 0.1138
Echinococcus multilocularis pyruvate kinase 0.0034 0.0095 0.0094
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0103 0.0102
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1052 0.7369 1
Toxoplasma gondii phosphofructokinase PFKII 0.0063 0.0301 0.2152
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma brucei AAA ATPase, putative 0.0021 0.0001 0.00000024592
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Chlamydia trachomatis phosphoglycerate kinase 0.0191 0.1216 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0262 0.1721 0.172
Onchocerca volvulus 0.0165 0.1029 0.1113
Trichomonas vaginalis ran, putative 0.0046 0.018 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Mycobacterium ulcerans 6-phosphofructokinase 0.0233 0.1513 0.3002
Loa Loa (eye worm) PHD-finger family protein 0.0127 0.076 0.0937
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0059 0.0276 0.1613
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0065 0.0068
Mycobacterium tuberculosis Conserved protein 0.0165 0.1029 0.1284
Trypanosoma brucei transcription factor BTF3, putative 0.0077 0.0401 0.0425
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0059 0.0273 0.0289
Trypanosoma brucei DNA polymerase IV, putative 0.014 0.0853 0.0905
Loa Loa (eye worm) hypothetical protein 0.0396 0.2677 0.3305
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Toxoplasma gondii NADPH-glutathione reductase 0.0059 0.0276 0.197
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.014 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0081 0.0429 0.0455
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0057 0.0259 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0323 0.2162 0.216
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.0276 0.0292
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.005 0.021 0.0258
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0063 0.0301 0.0326
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0009 0.001
Brugia malayi Bloom's syndrome protein homolog 0.0093 0.0515 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.1299 0.1405
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0044 0.0163 0.02
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0046 0.018 0.019
Toxoplasma gondii NAC domain-containing protein 0.0077 0.0401 0.2868
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.007 0.0353 0.0374
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.007 0.035 0.0349
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Onchocerca volvulus 0.0165 0.1029 0.1113
Loa Loa (eye worm) hypothetical protein 0.0026 0.0035 0.0042
Leishmania major ATP-dependent phosphofructokinase 0.0233 0.1513 0.1606
Echinococcus multilocularis zinc finger protein 0.0119 0.0703 0.0702
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0046 0.018 0.019
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0165 0.1029 0.1028
Loa Loa (eye worm) hypothetical protein 0.0262 0.1721 0.2124
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0065 0.046
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0155 0.0956 0.1848
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0103 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Brugia malayi phosphofructokinase 0.0233 0.1513 0.1867
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.039 0.2639 0.3497
Schistosoma mansoni hypothetical protein 0.0086 0.0464 0.0462
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0633 0.4377 0.4649
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0022 0.0009 0.001
Trichomonas vaginalis bromodomain containing protein, putative 0.0021 0.0001 0.0001
Echinococcus granulosus ATP dependent DNA helicase Q1 0.005 0.021 0.0209
Echinococcus granulosus chromobox protein 1 0.0078 0.0411 0.0409
Mycobacterium leprae conserved hypothetical protein 0.0165 0.1029 0.2905
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0057 0.0259 0.0274
Trypanosoma cruzi trypanothione reductase, putative 0.0171 0.1074 0.114
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0059 0.0276 0.0275
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0343 0.2306 0.2305
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0044 0.0169 0.1204
Loa Loa (eye worm) jmjC domain-containing protein 0.0262 0.1727 0.2131
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0021 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0609 0.066
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0188 0.1197 0.127
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Schistosoma mansoni phosphatidylserine receptor 0.0057 0.0259 0.0258
Trichomonas vaginalis esterase, putative 0.0165 0.1029 0.1114
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0214 0.0231
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0021 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0024 0.0024 0.0024
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0632 0.4365 0.4364
Loa Loa (eye worm) jmjC domain-containing protein 0.0226 0.1469 0.1813
Trypanosoma brucei DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Echinococcus granulosus importin subunit beta 1 0.0062 0.0298 0.0297
Brugia malayi beta-lactamase family protein 0.0165 0.1029 0.1269
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0104 0.0598 0.0648
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0103 0.0108
Echinococcus multilocularis geminin 0.0958 0.6694 0.6693
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0103 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.004 0.014 0.0151
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0021 0.0001 0.00000023148
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0021 0.0001 0.00000023148
Loa Loa (eye worm) hypothetical protein 0.0165 0.1029 0.1269
Echinococcus granulosus dna polymerase kappa 0.0155 0.0956 0.0955
Trichomonas vaginalis phosphofructokinase, putative 0.0063 0.0301 0.0326
Brugia malayi 6-phosphofructokinase 0.0233 0.1513 0.1867
Plasmodium falciparum basic transcription factor 3b, putative 0.0077 0.0401 0.329
Trichomonas vaginalis bromodomain-containing protein, putative 0.0021 0.0001 0.0001
Trypanosoma cruzi ISWI complex protein 0.0086 0.0464 0.0491
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0061 0.0291 0.0315
Plasmodium vivax importin-beta 2, putative 0.0062 0.0298 0.2442
Entamoeba histolytica phosphofructokinase, putative 0.0233 0.1513 0.2182
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0991 0.6931 0.7504
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0191 0.1216 0.1541
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0165 0.0178
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0042 0.0149 0.1061
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0149 0.0161
Leishmania major hypothetical protein, conserved 0.0165 0.1029 0.1092
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0191 0.1216 0.3487
Echinococcus granulosus dnaJ subfamily B 0.0494 0.3381 0.338
Giardia lamblia PHD finger protein 15 0.0127 0.076 0.1095
Echinococcus granulosus histone acetyltransferase MYST2 0.018 0.1139 0.1138
Trypanosoma cruzi DNA polymerase kappa, putative 0.0155 0.0956 0.1015
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0164 0.1342
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0044 0.0164 0.1342
Entamoeba histolytica peptidase, C54 family 0.0024 0.0024 0.0032
Trichomonas vaginalis set domain proteins, putative 0.1314 0.9236 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0332 0.0331

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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