Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0903 | 1 | 1 |
Onchocerca volvulus | 0.0253 | 0 | 0.5 | |
Schistosoma mansoni | adenosylhomocysteinase | 0.0903 | 1 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0903 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0903 | 1 | 1 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0903 | 1 | 1 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0903 | 1 | 1 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0903 | 1 | 1 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0903 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0559 | 0.4706 | 0.4706 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0903 | 1 | 1 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0903 | 1 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0903 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0903 | 1 | 1 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0903 | 1 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0903 | 1 | 1 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0903 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0559 | 0.4706 | 0.4706 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0903 | 1 | 1 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0903 | 1 | 1 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0903 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0559 | 0.4706 | 0.4706 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0559 | 0.4706 | 0.4706 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.