Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0448 | 0.2972 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0172 | 0.0998 | 0.0998 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0111 | 0.056 | 0.056 |
Echinococcus granulosus | glutamyl tRNAGln amidotransferase subunit A | 0.0172 | 0.0998 | 0.0998 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.0275 | 0.0275 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0209 | 0.0209 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0209 | 0.0209 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0105 | 0.0518 | 0.0518 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.0512 | 0.0512 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0111 | 0.056 | 0.056 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0448 | 0.2972 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.1428 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0287 | 0.1823 | 0.1823 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0199 | 0.1187 | 0.1892 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0209 | 0.0209 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0277 | 0.1749 | 0.1749 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1428 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0209 | 0.0209 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0448 | 0.2972 | 1 |
Brugia malayi | Amidase family protein | 0.0172 | 0.0998 | 0.0998 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0277 | 0.1749 | 0.1749 |
Brugia malayi | Amidase family protein | 0.0172 | 0.0998 | 0.0998 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0199 | 0.1187 | 0.1892 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0209 | 0.0209 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0448 | 0.2972 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0111 | 0.056 | 0.056 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0209 | 0.0209 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0188 | 0.1114 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0522 | 0.0522 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0448 | 0.2972 | 0.5 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0448 | 0.2972 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0209 | 0.0209 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0448 | 0.2972 | 1 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0448 | 0.2972 | 0.2972 |
Brugia malayi | putative amidase | 0.0172 | 0.0998 | 0.0998 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0448 | 0.2972 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0209 | 0.0209 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1428 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0448 | 0.2972 | 0.2972 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0448 | 0.2972 | 0.2972 |
Loa Loa (eye worm) | hypothetical protein | 0.1428 | 1 | 1 |
Echinococcus multilocularis | glutamyl tRNA(Gln) amidotransferase subunit A | 0.0172 | 0.0998 | 0.0998 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.1428 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0209 | 0.0209 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0172 | 0.0998 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0275 | 0.0275 |
Schistosoma mansoni | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0172 | 0.0998 | 0.0998 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0172 | 0.0998 | 0.5 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0448 | 0.2972 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0209 | 0.0209 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0448 | 0.2972 | 1 |
Brugia malayi | Adenosylhomocysteinase | 0.0448 | 0.2972 | 0.2972 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0277 | 0.1749 | 0.1749 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0172 | 0.0998 | 0.0998 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | amidase | 0.0172 | 0.0998 | 0.0998 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.0512 | 0.0512 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.0275 | 0.0275 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0448 | 0.2972 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.1428 | 1 | 1 |
Schistosoma mansoni | amidase | 0.1428 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0277 | 0.1749 | 0.1749 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0448 | 0.2972 | 0.2972 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0287 | 0.1823 | 0.1823 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0448 | 0.2972 | 0.5 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0448 | 0.2972 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0209 | 0.0209 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0448 | 0.2972 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0172 | 0.0998 | 0.0998 |
Loa Loa (eye worm) | amidase | 0.0172 | 0.0998 | 0.0998 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0209 | 0.0209 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0172 | 0.0998 | 0.5 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0209 | 0.0209 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0287 | 0.1823 | 0.4778 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0188 | 0.1114 | 0.1562 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.