Detailed information for compound 2075795

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 297.804 | Formula: C13H16ClN3OS
  • H donors: 2 H acceptors: 3 LogP: 2.47 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cc(nc(n1)c1cscc1)C1CCNCC1.Cl
  • InChi: 1S/C13H15N3OS.ClH/c17-12-7-11(9-1-4-14-5-2-9)15-13(16-12)10-3-6-18-8-10;/h3,6-9,14H,1-2,4-5H2,(H,15,16,17);1H
  • InChiKey: WWYSTTMCGMORAJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0263 0.0583 0.0746
Loa Loa (eye worm) glutathione reductase 0.0103 0.0185 0.0185
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0134 0.0262 0.2613
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.006 0.0078 0.118
Toxoplasma gondii ABC1 family protein 0.006 0.008 0.1162
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0105 0.0191 0.1872
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0091 0.0157 0.0201
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1003 0.2418 0.2418
Mycobacterium tuberculosis Probable oxidoreductase 0.026 0.0575 0.5992
Mycobacterium ulcerans glutamine synthetase GlnA1 0.0089 0.015 0.0637
Loa Loa (eye worm) hypothetical protein 0.0373 0.0857 0.0857
Echinococcus granulosus chromobox protein 1 0.0087 0.0146 0.0187
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0043 0.0098
Schistosoma mansoni hypothetical protein 0.0092 0.016 0.0205
Schistosoma mansoni cpg binding protein 0.0047 0.0048 0.0061
Echinococcus granulosus neuropeptide s receptor 0.2198 0.5381 0.6893
Schistosoma mansoni nuclear hormone receptor 0.1003 0.2418 0.3097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Trypanosoma cruzi importin beta-1 subunit, putative 0.0045 0.0043 0.0525
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0172 0.0357 0.4626
Brugia malayi PAS domain containing protein 0.121 0.2932 0.2932
Loa Loa (eye worm) 6-phosphofructokinase 0.0239 0.0523 0.0523
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0225 0.339
Echinococcus granulosus histone acetyltransferase KAT2B 0.0182 0.0382 0.0489
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0172 0.0357 0.0457
Loa Loa (eye worm) hypothetical protein 0.0056 0.007 0.007
Schistosoma mansoni alpha-glucosidase 0.0286 0.0641 0.0821
Brugia malayi Cytochrome P450 family protein 0.0105 0.0191 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0109 0.1593
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0105 0.0192 0.0192
Echinococcus granulosus thioredoxin glutathione reductase 0.0103 0.0185 0.0237
Loa Loa (eye worm) hypothetical protein 0.053 0.1245 0.1245
Mycobacterium tuberculosis Conserved protein 0.006 0.008 0.0675
Leishmania major glutamine synthetase, putative 0.0138 0.0272 0.3475
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0108 0.0199 0.0255
Brugia malayi hypothetical protein 0.0473 0.1104 0.1104
Plasmodium vivax glutamine synthetase, putative 0.0089 0.015 0.2216
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0105 0.0191 0.0832
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0036 0.002 0.002
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0473 0.1104 0.1414
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0182 0.0382 0.5568
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.009 0.0155 0.0155
Trichomonas vaginalis bromodomain-containing protein, putative 0.0182 0.0382 0.0935
Brugia malayi orphan nuclear receptor NR2E1 0.0473 0.1104 0.1104
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0337 0.0767 0.0982
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0019 0.0037
Entamoeba histolytica hypothetical protein 0.1043 0.2518 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.002 0.0218
Leishmania major ATP-dependent phosphofructokinase 0.0239 0.0523 0.6904
Brugia malayi Matrixin family protein 0.0337 0.0767 0.0767
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0172 0.0357 0.0457
Echinococcus multilocularis FTZ F1 alpha 0.1003 0.2418 0.2424
Brugia malayi Calcitonin receptor-like protein seb-1 0.0292 0.0655 0.0655
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.014 0.0277 0.0355
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0105 0.0192 0.0192
Schistosoma mansoni ankyrin 23/unc44 0.009 0.0155 0.0198
Trichomonas vaginalis guanylate cyclase, putative 0.0329 0.0747 0.1836
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.0073 0.0094
Schistosoma mansoni hypothetical protein 0.0092 0.016 0.0205
Trypanosoma cruzi tyrosine aminotransferase 0.019 0.0401 0.533
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0019 0.0019
Echinococcus multilocularis thyroid hormone receptor alpha 0.1143 0.2765 0.2771
Mycobacterium ulcerans 6-phosphofructokinase 0.0239 0.0523 0.2412
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0058 0.0726
Brugia malayi cathepsin L-like precursor 0.0039 0.0026 0.0026
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0105 0.0191 0.0462
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0329 0.0747 0.9976
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0613 0.145 0.1857
Schistosoma mansoni hypothetical protein 0.1043 0.2518 0.3225
Loa Loa (eye worm) hypothetical protein 0.0408 0.0943 0.0943
Echinococcus granulosus single minded 2 0.0881 0.2115 0.2709
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0036 0.002 0.004
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0036 0.002 0.002
Echinococcus granulosus serine:threonine protein kinase PLK1 0.008 0.013 0.0166
Leishmania major cathepsin L-like protease 0.0058 0.0073 0.0751
Schistosoma mansoni thyroid hormone receptor 0.1143 0.2765 0.3541
Brugia malayi Cytochrome P450 family protein 0.0268 0.0595 0.0595
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0073 0.0171
Echinococcus multilocularis 0.0105 0.0191 0.0192
Schistosoma mansoni jumonji/arid domain-containing protein 0.0106 0.0194 0.0248
Entamoeba histolytica glutamine synthetase, putative 0.0035 0.0017 0.005
Echinococcus granulosus snurportin 1 0.0599 0.1415 0.1813
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0329 0.0747 0.9977
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0019 0.0009
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0033 0.0033
Onchocerca volvulus 0.006 0.008 0.0169
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0239 0.0523 0.5431
Echinococcus multilocularis jumonji domain containing protein 0.0034 0.0016 0.0016
Echinococcus granulosus nuclear receptor nhr 48 0.0473 0.1104 0.1414
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.1003 0.2418 0.3097
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0599 0.1415 0.1415
Loa Loa (eye worm) hypothetical protein 0.0193 0.041 0.041
Brugia malayi Pre-SET motif family protein 0.021 0.0452 0.0452
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0191 0.2826
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Brugia malayi Ets-domain containing protein 0.0078 0.0125 0.0125
Onchocerca volvulus 0.006 0.008 0.0169
Onchocerca volvulus 0.0417 0.0964 0.2355
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0019 0.0281
Onchocerca volvulus 0.0235 0.0514 0.1242
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0042 0.0034 0.0044
Onchocerca volvulus Netrin receptor homolog 0.009 0.0155 0.0355
Echinococcus multilocularis lamin 0.0417 0.0964 0.0966
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0053 0.0121
Trypanosoma cruzi polo-like protein kinase, putative 0.008 0.013 0.1686
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0105 0.0191 0.1872
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0296 0.0664 1
Schistosoma mansoni ets-related 0.0238 0.052 0.0666
Brugia malayi MH1 domain containing protein 0.005 0.0056 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0191 0.2504
Loa Loa (eye worm) hypothetical protein 0.0193 0.041 0.041
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0211 0.0453 0.0453
Echinococcus multilocularis Smad4 0.005 0.0056 0.0056
Brugia malayi hypothetical protein 0.0031 0.0006 0.0006
Onchocerca volvulus Matrilysin homolog 0.0337 0.0767 0.1867
Loa Loa (eye worm) hypothetical protein 0.0051 0.0058 0.0058
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0087 0.0146 0.0147
Brugia malayi Fli-1 protein 0.0238 0.052 0.052
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1226 0.297 0.2977
Loa Loa (eye worm) fibroinase 0.0058 0.0073 0.0073
Brugia malayi glutathione reductase 0.0103 0.0185 0.0185
Schistosoma mansoni hypothetical protein 0.0105 0.0191 0.0245
Schistosoma mansoni bromodomain containing protein 0.0091 0.0157 0.0201
Loa Loa (eye worm) CXXC zinc finger family protein 0.0047 0.0048 0.0048
Onchocerca volvulus Glutamine synthetase homolog 0.0089 0.015 0.0344
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0119 0.0225 0.6315
Echinococcus multilocularis snurportin 1 0.0599 0.1415 0.1419
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0114 0.0272
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0329 0.0747 0.1836
Echinococcus granulosus cathepsin L 0.003 0.0004 0.0005
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0063 0.0088 0.0088
Echinococcus granulosus ubiquitin specific protease 41 0.0172 0.0357 0.0457
Brugia malayi latrophilin 2 splice variant baaae 0.02 0.0426 0.0426
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1226 0.297 0.3804
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0053 0.0121
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0114 0.0272
Loa Loa (eye worm) hypothetical protein 0.02 0.0426 0.0426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Loa Loa (eye worm) hypothetical protein 0.0163 0.0334 0.0334
Brugia malayi Muscleblind-like protein 0.0296 0.0666 0.0666
Brugia malayi Cathepsin L-like precursor 0.0039 0.0026 0.0026
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0305 0.0686 0.0688
Schistosoma mansoni glutamine synthetase 1 2 (glutamate-amonia ligase) (gs) 0.0138 0.0272 0.0349
Schistosoma mansoni chromobox protein 0.0087 0.0146 0.0187
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Plasmodium vivax SET domain protein, putative 0.021 0.0452 0.6791
Schistosoma mansoni RAR-like nuclear receptor 0.1003 0.2418 0.3097
Echinococcus granulosus GPCR family 2 0.0092 0.016 0.0205
Echinococcus granulosus dna polymerase eta 0.0061 0.0083 0.0106
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0172 0.0357 0.0357
Brugia malayi hypothetical protein 0.1187 0.2874 0.2874
Entamoeba histolytica phosphofructokinase, putative 0.0239 0.0523 0.2064
Brugia malayi intermediate filament protein 0.0417 0.0964 0.0964
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.033 0.0749 1
Loa Loa (eye worm) hypothetical protein 0.0337 0.0767 0.0767
Brugia malayi nuclear hormone receptor family member odr-7 0.0473 0.1104 0.1104
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0036 0.002 0.0025
Brugia malayi small heat shock protein 0.1764 0.4307 0.4307
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0105 0.0191 0.1872
Brugia malayi PHD-finger family protein 0.0047 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0329 0.0747 0.0747
Loa Loa (eye worm) hypothetical protein 0.0201 0.0429 0.0429
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0083 0.0705
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.000000000031631 0.00000000046086
Leishmania major importin beta-1 subunit, putative 0.0045 0.0043 0.0338
Entamoeba histolytica hypothetical protein 0.1043 0.2518 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0296 0.0664 0.0666
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0105 0.0191 0.1872
Loa Loa (eye worm) CHromoDomain protein family member 0.003 0.0004 0.0004
Trypanosoma brucei unspecified product 0.0042 0.0035 0.0472
Loa Loa (eye worm) MH2 domain-containing protein 0.005 0.0056 0.0056
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0036 0.002 0.002
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0073 0.0171
Loa Loa (eye worm) hypothetical protein 0.0061 0.0083 0.0083
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Schistosoma mansoni glutamine synthetase bacteria 0.0035 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.053 0.1245 0.1245
Schistosoma mansoni ap endonuclease 0.0119 0.0225 0.0288
Echinococcus granulosus Ankyrin repeat domain containing protein 0.01 0.0178 0.0228
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0019 0.0194
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.0033 0.0495
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0058 0.0726
Giardia lamblia DINP protein human, muc B family 0.0072 0.0109 0.3066
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0105 0.0191 0.0832
Brugia malayi hypothetical protein 0.0033 0.0013 0.0013
Echinococcus multilocularis muscleblind protein 0.0296 0.0666 0.0667
Echinococcus granulosus neutral alpha glucosidase AB 0.0074 0.0114 0.0146
Echinococcus granulosus 6 phosphofructokinase 0.0239 0.0523 0.067
Loa Loa (eye worm) RNA binding protein 0.0119 0.0226 0.0226
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.026 0.0575 0.598
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Loa Loa (eye worm) hypothetical protein 0.035 0.0799 0.0799
Mycobacterium tuberculosis Probable hydrolase 0.006 0.008 0.0675
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.01 0.0178 0.0228
Leishmania major hypothetical protein, conserved 0.006 0.008 0.0836
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Leishmania major cathepsin L-like protease 0.022 0.0475 0.6249
Brugia malayi Nuclear hormone receptor family member nhr-40 0.1003 0.2418 0.2418
Onchocerca volvulus 0.0124 0.0239 0.0563
Brugia malayi hypothetical protein 0.0174 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0067 0.0097 0.0097
Echinococcus multilocularis dnaJ subfamily B 0.0374 0.0857 0.0859
Brugia malayi hypothetical protein 0.0039 0.0027 0.0027
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0053 0.0652
Echinococcus multilocularis expressed protein 0.0414 0.0957 0.096
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.007 0.1014
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.007 0.0991
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1003 0.2418 0.2424
Echinococcus granulosus adam 17 protease 0.0245 0.0539 0.069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Echinococcus multilocularis dna polymerase kappa 0.0105 0.0191 0.0191
Leishmania major protein kinase, putative 0.033 0.0749 1
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0053 0.0121
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.014 0.0277 0.0278
Schistosoma mansoni alpha glucosidase 0.0074 0.0114 0.0146
Loa Loa (eye worm) cytochrome P450 family protein 0.0268 0.0595 0.0595
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.1003 0.2418 0.2418
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0292 0.0655 0.0655
Brugia malayi Nuclear hormone receptor E75 0.0473 0.1104 0.1104
Echinococcus multilocularis neutral alpha glucosidase AB 0.0074 0.0114 0.0114
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.053 0.1245 0.1245
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Loa Loa (eye worm) DR-78 0.0473 0.1104 0.1104
Brugia malayi nuclear hormone receptor family member nhr-6 0.0473 0.1104 0.1104
Schistosoma mansoni hypothetical protein 0.014 0.0277 0.0355
Schistosoma mansoni ran 0.0041 0.0033 0.0042
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0047 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0599 0.1415 0.1813
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.006 0.008 0.0102
Brugia malayi Steroid receptor seven-up type 2 0.1003 0.2418 0.2418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Mycobacterium leprae conserved hypothetical protein 0.006 0.008 0.0647
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0026 0.0088
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0329 0.0747 0.1836
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0105 0.0191 0.1872
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0036 0.002 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0226 0.0289
Schistosoma mansoni aldehyde dehydrogenase 0.0305 0.0686 0.0879
Loa Loa (eye worm) hypothetical protein 0.0082 0.0134 0.0134
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0004 0.0005
Echinococcus granulosus death domain containing protein 0.009 0.0155 0.0198
Entamoeba histolytica tartrate dehydrogenase, putative 0.0036 0.002 0.0062
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0092 0.016 0.016
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1003 0.2418 0.595
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0065 0.0152
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0053 0.0121
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0263 0.0583 0.2696
Brugia malayi steroid hormone receptor 0.1003 0.2418 0.2418
Treponema pallidum exodeoxyribonuclease (exoA) 0.0119 0.0225 0.4095
Onchocerca volvulus Protein cycle homolog 0.0047 0.0047 0.0088
Schistosoma mansoni nuclear hormone receptor 0.0473 0.1104 0.1414
Trypanosoma cruzi tyrosine aminotransferase, putative 0.019 0.0401 0.533
Echinococcus multilocularis lysosomal alpha glucosidase 0.0333 0.0756 0.0758
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0065 0.0091 0.0987
Leishmania major cytochrome p450-like protein 0.0105 0.0191 0.2364
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0043 0.0626
Schistosoma mansoni transcription factor LCR-F1 0.1043 0.2518 0.3225
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Loa Loa (eye worm) cytochrome P450 0.0105 0.0191 0.0191
Leishmania major cathepsin L-like protease 0.0058 0.0073 0.0751
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Entamoeba histolytica glutamine synthetase, putative 0.0035 0.0017 0.005
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0105 0.0191 0.1872
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0105 0.0191 0.1872
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0296 0.0664 0.0851
Brugia malayi Protein kinase domain containing protein 0.0091 0.0157 0.0157
Schistosoma mansoni hypothetical protein 0.009 0.0155 0.0198
Brugia malayi conserved hypotetical protein 0.0473 0.1104 0.1104
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0058 0.0877
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0063 0.0088 0.095
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0119 0.0225 0.2967
Mycobacterium tuberculosis Probable lipase LipD 0.006 0.008 0.0675
Onchocerca volvulus 0.0881 0.2116 0.5203
Brugia malayi Nuclear hormone receptor family member nhr-31 0.1003 0.2418 0.2418
Brugia malayi hypothetical protein 0.0031 0.0006 0.0006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0088 0.1126
Entamoeba histolytica hypothetical protein 0.0045 0.0043 0.0156
Echinococcus multilocularis bloom syndrome protein 0.0068 0.0099 0.0099
Echinococcus multilocularis microtubule associated protein 2 0.0664 0.1577 0.1581
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.1003 0.2418 0.2424
Schistosoma mansoni smad1 5 8 and 0.005 0.0056 0.0071
Brugia malayi Death domain containing protein 0.009 0.0155 0.0155
Brugia malayi isocitrate dehydrogenase 0.0296 0.0664 0.0664
Schistosoma mansoni DNA polymerase eta 0.0061 0.0083 0.0106
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0058 0.0073 0.0074
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0282 0.063 0.063
Trypanosoma brucei hypothetical protein, conserved 0.006 0.008 0.1145
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0105 0.0191 0.0832
Echinococcus granulosus muscleblind protein 0.0296 0.0666 0.0853
Loa Loa (eye worm) hypothetical protein 0.0411 0.0949 0.0949
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0239 0.0523 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0263 0.0583 0.0584
Brugia malayi hypothetical protein 0.053 0.1245 0.1245
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0019 0.0219
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0105 0.0191 0.2512
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0092 0.016 0.016
Trypanosoma cruzi cytochrome P450, putative 0.0268 0.0595 0.7933
Brugia malayi Latrophilin receptor protein 2 0.0092 0.016 0.016
Onchocerca volvulus Matrix metalloproteinase homolog 0.0748 0.1785 0.4384
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0033 0.0435
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Entamoeba histolytica cysteine protease, putative 0.0058 0.0073 0.0276
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0053 0.0736
Trypanosoma cruzi tyrosine aminotransferase 0.019 0.0401 0.533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.0033 0.0923
Brugia malayi beta-lactamase family protein 0.006 0.008 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0225 0.0547
Trichomonas vaginalis DNA polymerase eta, putative 0.0105 0.0191 0.0462
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0083 0.1051
Loa Loa (eye worm) nuclear receptor NHR-67 0.0473 0.1104 0.1104
Toxoplasma gondii exonuclease III APE 0.0119 0.0225 0.3281
Loa Loa (eye worm) hypothetical protein 0.0125 0.0241 0.0241
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Loa Loa (eye worm) RecQ helicase 0.0068 0.0099 0.0099
Loa Loa (eye worm) phosphofructokinase 0.0239 0.0523 0.0523
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.0015 0.0015
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0463 0.108 0.1082
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0019 0.0194
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.033 0.0749 1
Echinococcus granulosus cytochrome P450 2K1 0.0105 0.0191 0.0245
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0034 0.0015 0.0212
Brugia malayi MH2 domain containing protein 0.005 0.0056 0.0056
Echinococcus granulosus dna polymerase kappa 0.0105 0.0191 0.0244
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1003 0.2418 0.2418
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0329 0.0747 0.1836
Onchocerca volvulus 0.0473 0.1104 0.2701
Trichomonas vaginalis set domain proteins, putative 0.1663 0.4054 1
Trypanosoma brucei protein kinase, putative 0.0049 0.0053 0.0736
Trypanosoma cruzi tyrosine aminotransferase, putative 0.019 0.0401 0.533
Brugia malayi nuclear receptor RXR 0.053 0.1245 0.1245
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0105 0.0192 0.0245
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0105 0.0191 0.0832
Brugia malayi phosphofructokinase 0.0239 0.0523 0.0523
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.033 0.0748 0.075
Echinococcus multilocularis cathepsin L cysteine protease 0.0058 0.0073 0.0074
Echinococcus multilocularis adam 0.0039 0.0027 0.0027
Leishmania major trypanothione reductase 0.0103 0.0185 0.2274
Entamoeba histolytica phosphofructokinase, putative 0.0239 0.0523 0.2064
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0019 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.1003 0.2418 0.3097
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0053 0.0467
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0019 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0296 0.0664 0.0666
Giardia lamblia Histone acetyltransferase GCN5 0.0164 0.0338 0.9485
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.0747 0.1836
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0058 0.0073 0.0073
Entamoeba histolytica Ran family GTPase 0.0041 0.0033 0.0114
Mycobacterium leprae Conserved hypothetical protein 0.0105 0.0191 0.1848
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.006 0.008 0.008
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0019 0.0272
Onchocerca volvulus 0.0478 0.1116 0.2731
Echinococcus granulosus lysosomal alpha glucosidase 0.0333 0.0756 0.0968
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.1003 0.2418 0.3097
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0073 0.0111 0.0247
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Trypanosoma cruzi polo-like protein kinase, putative 0.008 0.013 0.1686
Loa Loa (eye worm) hypothetical protein 0.0337 0.0767 0.0767
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0086 0.1238
Mycobacterium tuberculosis Probable esterase LipL 0.006 0.008 0.0675
Loa Loa (eye worm) hypothetical protein 0.0045 0.0041 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0114 0.147
Schistosoma mansoni lamin 0.0417 0.0964 0.1235
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0296 0.0664 0.8861
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0409 0.0945 0.0945
Brugia malayi Bromodomain containing protein 0.0105 0.0191 0.0191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0033 0.0435
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0033 0.0033
Loa Loa (eye worm) isocitrate dehydrogenase 0.0296 0.0664 0.0664
Onchocerca volvulus 0.0058 0.0073 0.0154
Schistosoma mansoni smad 0.005 0.0056 0.0071
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0245 0.0539 0.0539
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0296 0.0664 0.0666
Toxoplasma gondii cytochrome p450 superfamily protein 0.0105 0.0191 0.2788
Trypanosoma cruzi glutamine synthetase, putative 0.0138 0.0272 0.3601
Loa Loa (eye worm) matrix metalloproteinase 0.0337 0.0767 0.0767
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0105 0.0191 0.1872
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0417 0.0964 0.0964
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0083 0.0083
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0613 0.145 0.1453
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0092 0.016 0.0205
Schistosoma mansoni retinoid-x-receptor (RXR) 0.1003 0.2418 0.3097
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0329 0.0747 0.1836
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0473 0.1104 0.1414
Loa Loa (eye worm) Smad1 0.005 0.0056 0.0056
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0005 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.0015 0.0219
Schistosoma mansoni nuclear receptor 0.0473 0.1104 0.1414
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0172 0.0357 0.0457
Schistosoma mansoni nuclear hormone receptor 0.0473 0.1104 0.1414
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0172 0.0357 0.1402
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.1003 0.2418 0.3097
Mycobacterium tuberculosis Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) 0.0089 0.015 0.1434
Brugia malayi nuclear hormone receptor 0.0473 0.1104 0.1104
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0201 0.0429 0.055
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0072 0.0109 0.1242
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0073 0.093
Echinococcus multilocularis neuropeptide s receptor 0.2198 0.5381 0.5394
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0065 0.0091 0.2541
Brugia malayi nuclear receptor RXR 0.0473 0.1104 0.1104
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0172 0.0357 0.5339
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0033 0.0386
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Echinococcus multilocularis cathepsin L 0.003 0.0004 0.0004
Entamoeba histolytica heat shock transcription factor, putative 0.0073 0.0111 0.0427
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1003 0.2418 0.3097
Schistosoma mansoni hypothetical protein 0.3176 0.7808 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.1764 0.4307 0.4307
Plasmodium falciparum glutamine synthetase, putative 0.0089 0.015 0.2265
Loa Loa (eye worm) nuclear hormone receptor 0.0473 0.1104 0.1104
Trypanosoma cruzi cruzipain precursor, putative 0.022 0.0475 0.6322
Echinococcus multilocularis ecdysone induced protein 78C 0.1003 0.2418 0.2424
Leishmania major cathepsin L-like protease 0.0058 0.0073 0.0751
Brugia malayi Nuclear hormone receptor E75 0.0473 0.1104 0.1104
Toxoplasma gondii aldehyde dehydrogenase 0.0305 0.0686 1
Schistosoma mansoni glutamine synthetase bacteria 0.0035 0.0017 0.0022
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0105 0.0191 0.0832
Brugia malayi bHLH-PAS transcription factor 0.0881 0.2115 0.2115
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Loa Loa (eye worm) MH2 domain-containing protein 0.0741 0.1769 0.1769
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0063 0.0088 0.0113
Trypanosoma cruzi cytochrome P450, putative 0.0268 0.0595 0.7933
Mycobacterium leprae Probable lipase LipE 0.006 0.008 0.0647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.053 0.1245 0.1594
Schistosoma mansoni netrin receptor unc5 0.009 0.0155 0.0198
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0305 0.0686 0.7184
Brugia malayi Isocitrate dehydrogenase 0.0296 0.0664 0.0664
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.009 0.0155 0.0198
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0105 0.0191 0.1872
Schistosoma mansoni cpg binding protein 0.0052 0.006 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Loa Loa (eye worm) hypothetical protein 0.0296 0.0666 0.0666
Echinococcus granulosus dnaJ subfamily B 0.0374 0.0857 0.1098
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0058 0.0073 0.0173
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0473 0.1104 0.1107
Loa Loa (eye worm) hypothetical protein 0.406 1 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0376 0.0864 0.0866
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0226 0.0289
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.0511 0.5298
Echinococcus granulosus thyroid hormone receptor alpha 0.0473 0.1104 0.1414
Echinococcus multilocularis survival motor neuron protein 1 0.1187 0.2874 0.2881
Loa Loa (eye worm) hypothetical protein 0.0174 0.0362 0.0362
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0172 0.0357 0.4731
Schistosoma mansoni cathepsin F (C01 family) 0.0039 0.0026 0.0034
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0047 0.0046 0.0046
Brugia malayi hypothetical protein 0.0051 0.0058 0.0058
Brugia malayi tyrosine aminotransferase 0.019 0.0401 0.0401
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.1043 0.2518 0.3225
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0105 0.0191 0.1872
Brugia malayi TAR-binding protein 0.0119 0.0226 0.0226
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.021 0.0452 0.6593
Onchocerca volvulus 0.0058 0.0073 0.0154
Schistosoma mansoni importin beta-1 0.0056 0.007 0.0089
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.1003 0.2418 0.3097
Loa Loa (eye worm) 6-phosphofructokinase 0.0239 0.0523 0.0523
Echinococcus granulosus jumonji domain containing protein 0.0034 0.0016 0.002
Brugia malayi hypothetical protein 0.053 0.1245 0.1245
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0105 0.0191 0.0832
Brugia malayi Cytochrome P450 family protein 0.0263 0.0582 0.0582
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.009 0.0155 0.0155
Schistosoma mansoni jumonji domain containing protein 0.0136 0.0267 0.0342
Onchocerca volvulus Cathepsin F homolog 0.0058 0.0073 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0226 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0296 0.0664 1
Echinococcus granulosus expressed protein 0.0414 0.0957 0.1226
Onchocerca volvulus 0.0047 0.0048 0.0091
Mycobacterium tuberculosis Probable reductase 0.0234 0.0511 0.5298
Leishmania major DNA polymerase kappa, putative 0.0072 0.0109 0.1242
Echinococcus multilocularis nuclear receptor nhr 48 0.0473 0.1104 0.1107
Leishmania major isocitrate dehydrogenase, putative 0.0036 0.002 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.0741 0.1769 0.1769
Trypanosoma brucei unspecified product 0.0094 0.0164 0.2419
Loa Loa (eye worm) ctsf protein 0.0058 0.0073 0.0073
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0134 0.0262 0.0639
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0305 0.0686 0.0879
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0223 0.0484 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0004 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0058 0.0073 0.0073
Schistosoma mansoni coup transcription factor 0.1003 0.2418 0.3097
Loa Loa (eye worm) hypothetical protein 0.009 0.0155 0.0155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0134 0.0262 0.117
Brugia malayi Cathepsin L-like precursor 0.0039 0.0026 0.0026
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0105 0.0191 0.2835
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.405 0.9976 1
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0036 0.002 0.0136
Schistosoma mansoni jumonji/arid domain-containing protein 0.0106 0.0194 0.0248
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0047 0.0047 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.1003 0.2418 0.3097
Echinococcus granulosus cathepsin L cysteine proteinase 0.0058 0.0073 0.0094
Schistosoma mansoni survival motor neuron protein 0.0242 0.0531 0.068
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0105 0.0191 0.1872
Trichomonas vaginalis penicillin-binding protein, putative 0.006 0.008 0.0188
Echinococcus granulosus intermediate filament protein 0.0417 0.0964 0.1235
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0058 0.0073 0.1106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0191 0.2504
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0119 0.0225 0.0993
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.1003 0.2418 0.2424
Brugia malayi Intermediate filament tail domain containing protein 0.0417 0.0964 0.0964
Leishmania major cathepsin L-like protease 0.022 0.0475 0.6249
Mycobacterium leprae Possible regulatory protein 0.0329 0.0747 0.7833
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0087 0.0146 0.0188
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Loa Loa (eye worm) acetyltransferase 0.0613 0.145 0.145
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0033 0.0386
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0211 0.0453 0.0454
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1003 0.2418 0.3097
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.0747 0.1836
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.014 0.0277 0.0278
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0473 0.1104 0.1414
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0114 0.0272
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.008 0.013 0.013
Mycobacterium ulcerans lipase LipD 0.006 0.008 0.03
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0119 0.0225 0.0225
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0119 0.0225 0.3348
Echinococcus granulosus neuropeptide receptor A26 0.2198 0.5381 0.6893
Loa Loa (eye worm) hypothetical protein 0.023 0.0502 0.0502
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0125 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0473 0.1104 0.1107
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0105 0.0191 0.0832
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0329 0.0747 0.1836
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Plasmodium falciparum glutathione reductase 0.0103 0.0185 0.2782
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0329 0.0747 1
Brugia malayi hypothetical protein 0.0047 0.0046 0.0046
Trichomonas vaginalis glutamine synthetase-bacteria, putative 0.0035 0.0017 0.0033
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0083 0.0312
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0211 0.0453 0.0581
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1461 0.3554 0.3554
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0473 0.1104 0.2701
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0004 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.021 0.0452 0.058
Loa Loa (eye worm) hypothetical protein 0.053 0.1245 0.1245
Onchocerca volvulus 0.0058 0.0073 0.0154
Mycobacterium leprae PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II) 0.0089 0.015 0.1408
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0105 0.0191 0.0832
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0004 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.007 0.0991
Schistosoma mansoni nuclear receptor nhr-48 0.0473 0.1104 0.1414
Loa Loa (eye worm) Gln-2 protein 0.0089 0.015 0.015
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.0511 0.5298
Brugia malayi Nuclear hormone receptor family member nhr-41 0.1003 0.2418 0.2418
Brugia malayi ecdysone receptor 0.0473 0.1104 0.1104
Loa Loa (eye worm) MH1 domain-containing protein 0.005 0.0056 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0105 0.0191 0.1872
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0091 0.1309
Brugia malayi RNA, U transporter 1 0.0159 0.0326 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Onchocerca volvulus 0.1003 0.2418 0.595
Echinococcus multilocularis smad 0.005 0.0056 0.0056
Loa Loa (eye worm) beta-lactamase 0.006 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0408 0.0943 0.0943
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0091 0.1364
Loa Loa (eye worm) hypothetical protein 0.0061 0.0083 0.0083
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0105 0.0191 0.0832
Plasmodium falciparum cysteine proteinase falcipain 1 0.003 0.0004 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0086 0.1238
Onchocerca volvulus 0.0373 0.0857 0.2089
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0105 0.0191 0.0832
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.0511 0.5283
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0263 0.0583 0.7719
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0146 0.0351
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0296 0.0664 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0119 0.0225 0.0288
Brugia malayi Glycosyl hydrolases family 31 protein 0.0333 0.0756 0.0756
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0092 0.016 0.016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0053 0.0652
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0034 0.0034
Onchocerca volvulus 0.0417 0.0964 0.2355
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.1043 0.2518 0.2524
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0019 0.0219
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0053 0.0053
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0074 0.0114 0.1657
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0182 0.0382 0.0935
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0053 0.0068
Loa Loa (eye worm) hypothetical protein 0.0292 0.0655 0.0655
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Schistosoma mansoni gabp alpha 0.0078 0.0125 0.016
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0004 0.0005
Echinococcus granulosus tar DNA binding protein 0.0119 0.0226 0.0289
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.006 0.008 0.0675
Brugia malayi MH2 domain containing protein 0.0741 0.1769 0.1769
Echinococcus multilocularis ubiquitin specific protease 41 0.0172 0.0357 0.0357
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0053 0.0769
Onchocerca volvulus 0.0039 0.0026 0.0037
Trypanosoma brucei cytochrome P450, putative 0.0268 0.0595 0.8953
Echinococcus multilocularis glutamine synthetase 0.0138 0.0272 0.0273
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.1003 0.2418 0.3097
Echinococcus multilocularis TGF beta signal transducer SmadC 0.005 0.0056 0.0056
Echinococcus granulosus cathepsin l1 0.0058 0.0073 0.0094
Mycobacterium ulcerans aldehyde dehydrogenase 0.0305 0.0686 0.319
Echinococcus multilocularis chromobox protein 1 0.0087 0.0146 0.0146
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0105 0.0191 0.1872
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0088 0.1126
Loa Loa (eye worm) hypothetical protein 0.0468 0.1092 0.1092
Brugia malayi jmjC domain containing protein 0.0106 0.0194 0.0194
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Brugia malayi RNA recognition motif domain containing protein 0.0119 0.0226 0.0226
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.033 0.0749 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Brugia malayi tailless protein 0.0473 0.1104 0.1104
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0134 0.0262 0.2635
Loa Loa (eye worm) cytochrome P450 family protein 0.0268 0.0595 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0062 0.0879
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Plasmodium falciparum glutathione reductase 0.0036 0.0019 0.0281
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.0511 0.5298
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0172 0.0357 0.0872
Echinococcus multilocularis GPCR, family 2 0.0092 0.016 0.016
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.008 0.0188
Echinococcus multilocularis dna polymerase eta 0.0061 0.0083 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0152 0.0308 0.0309
Brugia malayi Nuclear hormone receptor-like 1 0.1003 0.2418 0.2418
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0119 0.0225 0.0879
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0105 0.0191 0.2364
Brugia malayi serine/threonine-protein kinase plk-2 0.008 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Schistosoma mansoni Smad4 0.005 0.0056 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.008 0.0188
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0376 0.0864 0.0864
Brugia malayi 6-phosphofructokinase 0.0239 0.0523 0.0523
Toxoplasma gondii 6-phosphofructokinase 0.0065 0.0091 0.132
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0119 0.0225 0.3348
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0033 0.0042
Plasmodium vivax vivapain-2 0.0058 0.0073 0.105
Echinococcus multilocularis beta LACTamase domain containing family member 0.006 0.008 0.008
Echinococcus multilocularis 6 phosphofructokinase 0.0239 0.0523 0.0524
Loa Loa (eye worm) hypothetical protein 0.053 0.1245 0.1245
Plasmodium falciparum histone acetyltransferase GCN5 0.0164 0.0338 0.5092
Echinococcus granulosus Nuclear hormone receptor HR96 0.0473 0.1104 0.1414
Schistosoma mansoni hypothetical protein 0.02 0.0426 0.0546
Entamoeba histolytica phosphofructokinase, putative 0.0239 0.0523 0.2064
Plasmodium falciparum thioredoxin reductase 0.0103 0.0185 0.2782
Trypanosoma cruzi trypanothione reductase, putative 0.0103 0.0185 0.2424
Loa Loa (eye worm) hypothetical protein 0.0373 0.0857 0.0857
Brugia malayi ecdysteroid receptor 0.1003 0.2418 0.2418
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.053 0.1245 0.1594
Trypanosoma cruzi cysteine peptidase, putative 0.022 0.0475 0.6322
Loa Loa (eye worm) hypothetical protein 0.0063 0.0086 0.0086
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0036 0.002 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Plasmodium falciparum cysteine proteinase falcipain 3 0.0058 0.0073 0.1106
Schistosoma mansoni ran 0.0041 0.0033 0.0042
Entamoeba histolytica acetyltransferase, GNAT family 0.0164 0.0338 0.1329
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0103 0.0185 0.1802
Echinococcus granulosus zinc finger protein 0.004 0.0031 0.0039
Plasmodium falciparum thioredoxin reductase 0.0036 0.0019 0.0281
Echinococcus multilocularis cysteine protease 0.0058 0.0073 0.0074
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0039 0.0027 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0058 0.0877
Loa Loa (eye worm) hypoxia-induced factor 1 0.3684 0.9067 0.9067
Schistosoma mansoni 6-phosphofructokinase 0.0239 0.0523 0.067
Brugia malayi hypothetical protein 0.0125 0.0241 0.0241
Echinococcus multilocularis Ankyrin 0.0091 0.0157 0.0157
Brugia malayi Bromodomain containing protein 0.0042 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1003 0.2418 0.2418
Trichomonas vaginalis chromobox protein, putative 0.0087 0.0146 0.0351
Brugia malayi hypothetical protein 0.0134 0.0264 0.0264
Echinococcus granulosus beta LACTamase domain containing family member 0.006 0.008 0.0102
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0019 0.0037
Trypanosoma brucei trypanothione reductase 0.0103 0.0185 0.2736
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0058 0.0073 0.0074
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0058 0.0849
Schistosoma mansoni alpha-glucosidase 0.0286 0.0641 0.0821
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.1003 0.2418 0.2418
Loa Loa (eye worm) CYP4Cod1 0.0268 0.0595 0.0595
Entamoeba histolytica hypothetical protein 0.1043 0.2518 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0305 0.0686 0.319
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0002 0.0002
Schistosoma mansoni microtubule-associated protein tau 0.0664 0.1577 0.202
Echinococcus granulosus smad 0.005 0.0056 0.0071
Brugia malayi hypothetical protein 0.0473 0.1104 0.1104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0473 0.1104 0.1414
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Echinococcus multilocularis peregrin 0.0042 0.0036 0.0036
Echinococcus multilocularis netrin receptor unc 5 0.009 0.0155 0.0155
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0053 0.148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0092 0.016 0.0205
Schistosoma mansoni isocitrate dehydrogenase 0.0036 0.002 0.0025
Toxoplasma gondii cathepsin CPL 0.0058 0.0073 0.1071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Mycobacterium leprae putative cytochrome p450 0.0105 0.0191 0.1848
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0046
Schistosoma mansoni thyroid hormone receptor 0.1143 0.2765 0.3541
Brugia malayi Bromodomain containing protein 0.0059 0.0078 0.0078
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.053 0.1245 0.1594
Plasmodium vivax 6-phosphofructokinase, putative 0.0065 0.0091 0.1309
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0473 0.1104 0.1107
Echinococcus multilocularis zinc finger protein 0.004 0.0031 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0296 0.0664 0.9679
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.006 0.008 0.0675
Trichomonas vaginalis adenylate cyclase, putative 0.0329 0.0747 0.1836
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.0015 0.0015
Brugia malayi CXXC zinc finger family protein 0.0047 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0026
Echinococcus multilocularis transfer RNA-Lys 0.0881 0.2115 0.212
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0296 0.0666 0.0666
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0114 0.0272
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Mycobacterium ulcerans esterase/lipase LipP 0.006 0.008 0.03
Brugia malayi Hemopexin family protein 0.0478 0.1116 0.1116
Schistosoma mansoni smad1 5 8 and 0.005 0.0056 0.0071
Brugia malayi cytoplasmic intermediate filament protein 0.0223 0.0484 0.0484
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0201 0.0428 0.5687
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.0191 0.2826
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0182 0.0382 0.5568
Schistosoma mansoni lozenge 0.0047 0.0047 0.006
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0172 0.0357 0.0872
Echinococcus granulosus cpg binding protein 0.0052 0.006 0.0077
Brugia malayi RNA binding protein 0.0119 0.0226 0.0226
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0002 0.0003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0053 0.0652
Brugia malayi beta-lactamase family protein 0.006 0.008 0.008
Schistosoma mansoni intermediate filament proteins 0.0417 0.0964 0.1235
Mycobacterium ulcerans glutamine synthetase 0.0089 0.015 0.0637
Brugia malayi polk-prov protein 0.0063 0.0086 0.0086
Onchocerca volvulus Bile acid receptor homolog 0.1003 0.2418 0.595
Onchocerca volvulus 0.0192 0.0408 0.0981
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0019 0.0281
Echinococcus granulosus histone acetyltransferase KAT2B 0.0593 0.1401 0.1794
Schistosoma mansoni hypothetical protein 0.0092 0.016 0.0205
Onchocerca volvulus 0.0058 0.0073 0.0154
Schistosoma mansoni cytochrome P450 0.0105 0.0191 0.0245
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.008 0.013 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0119 0.0225 0.0547
Brugia malayi Matrixin family protein 0.0337 0.0767 0.0767
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0239 0.0523 0.6964
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Loa Loa (eye worm) hypothetical protein 0.0054 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0065 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.008 0.013 0.0312
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0114 0.0272
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.0015 0.0015
Loa Loa (eye worm) runx1 0.0047 0.0047 0.0047
Trypanosoma brucei unspecified product 0.0042 0.0035 0.0472
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.021 0.0452 0.0454
Schistosoma mansoni nuclear receptor 0.0473 0.1104 0.1414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Schistosoma mansoni hypothetical protein 0.0034 0.0015 0.0019
Brugia malayi Matrixin family protein 0.0337 0.0767 0.0767
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0305 0.0686 0.9139
Plasmodium vivax glutathione reductase, putative 0.0103 0.0185 0.2736
Onchocerca volvulus 0.0058 0.0073 0.0154
Entamoeba histolytica serine/threonine protein kinase, putative 0.008 0.013 0.05
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Onchocerca volvulus 0.0124 0.0239 0.0563
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0152 0.0308 0.0395
Mycobacterium leprae PROBABLE HYDROLASE 0.0411 0.0949 1
Leishmania major cytochrome p450-like protein 0.0268 0.0595 0.7892
Entamoeba histolytica heat shock transcription factor, putative 0.0073 0.0111 0.0427
Loa Loa (eye worm) hypothetical protein 0.0062 0.0085 0.0085
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0292 0.0655 0.0655
Brugia malayi Probable isocitrate dehydrogenase 0.0036 0.002 0.002
Brugia malayi Nuclear hormone receptor-like 1 0.053 0.1245 0.1245
Schistosoma mansoni TGF-beta signal transducer Smad2 0.005 0.0056 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Brugia malayi chromobox protein homolog 3 0.0054 0.0065 0.0065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0057 0.0073 0.0152
Echinococcus multilocularis tar DNA binding protein 0.0119 0.0226 0.0226
Leishmania major cytochrome p450-like protein 0.0105 0.0191 0.2364
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0053 0.0068
Onchocerca volvulus 0.0174 0.0362 0.0866
Onchocerca volvulus Protein ultraspiracle homolog 0.1003 0.2418 0.595
Mycobacterium ulcerans aldehyde dehydrogenase 0.0305 0.0686 0.319
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0105 0.0191 0.1872
Schistosoma mansoni serine/threonine protein kinase 0.008 0.013 0.0166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Echinococcus multilocularis thioredoxin glutathione reductase 0.0103 0.0185 0.0185
Trypanosoma cruzi tyrosine aminotransferase 0.019 0.0401 0.533
Brugia malayi CHD4 protein 0.003 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Trichomonas vaginalis importin beta-1, putative 0.0045 0.0043 0.0098
Trypanosoma cruzi tyrosine aminotransferase, putative 0.019 0.0401 0.533
Onchocerca volvulus 0.0242 0.0531 0.1284
Trichomonas vaginalis esterase, putative 0.006 0.008 0.0188
Loa Loa (eye worm) jmjC domain-containing protein 0.0106 0.0194 0.0194
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0065 0.0091 0.1364
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0036 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.1003 0.2418 0.2418
Loa Loa (eye worm) intermediate filament protein 0.0417 0.0964 0.0964
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0026 0.0056
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0063 0.0088 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Onchocerca volvulus Cathepsin L homolog 0.0058 0.0073 0.0154
Echinococcus multilocularis Protein lozenge 0.0047 0.0047 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0073 0.0276
Echinococcus granulosus histone lysine methyltransferase setb 0.023 0.0502 0.0643
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0172 0.0357 0.0457
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0473 0.1104 0.1107
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0296 0.0664 0.6948
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0384 0.0884 0.9302
Giardia lamblia Kinase, PLK 0.008 0.013 0.364
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0083 0.0106
Brugia malayi Nuclear hormone receptor-like 1 0.053 0.1245 0.1245
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.1003 0.2418 0.2424
Brugia malayi glutamine synthetase 0.0049 0.0053 0.0053
Plasmodium vivax vivapain-2 0.0058 0.0073 0.105
Brugia malayi beta-lactamase 0.006 0.008 0.008
Mycobacterium tuberculosis Probable conserved lipoprotein 0.006 0.008 0.0675
Brugia malayi MH2 domain containing protein 0.005 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Leishmania major cathepsin L-like protease 0.022 0.0475 0.6249
Loa Loa (eye worm) hypothetical protein 0.0054 0.0065 0.0065
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.003 0.0004 0.0005
Echinococcus multilocularis importin subunit beta 1 0.0056 0.007 0.007
Leishmania major cysteine peptidase A (CPA) 0.0058 0.0073 0.0751
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0058 0.0819
Trypanosoma brucei glutamine synthetase, putative 0.0138 0.0272 0.4064
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0019 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.008 0.1014
Echinococcus granulosus ecdysone induced protein 78C 0.1003 0.2418 0.3097
Brugia malayi Nuclear hormone receptor family member nhr-3 0.1003 0.2418 0.2418
Echinococcus multilocularis musashi 0.0417 0.0964 0.0966
Toxoplasma gondii phosphofructokinase PFKII 0.0065 0.0091 0.132
Brugia malayi photoreceptor-specific nuclear receptor 0.1003 0.2418 0.2418
Schistosoma mansoni blooms syndrome DNA helicase 0.0054 0.0063 0.0081
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0063 0.0088 0.0088
Plasmodium vivax importin-beta 2, putative 0.0056 0.007 0.0991
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0083 0.0083
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.033 0.0748 0.0958
Loa Loa (eye worm) tyrosine aminotransferase 0.019 0.0401 0.0401
Toxoplasma gondii isocitrate dehydrogenase 0.0296 0.0664 0.9679
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0119 0.0225 0.2236
Echinococcus multilocularis geminin 0.3176 0.7808 0.7826
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0191 0.0829
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0219
Brugia malayi nuclear receptor NHR-88 0.0473 0.1104 0.1104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0296 0.0664 0.8861
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0053 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0226 0.0289
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0296 0.0664 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.005 0.0056 0.0056
Echinococcus granulosus lamin 0.0417 0.0964 0.1235
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0083 0.1187
Trichomonas vaginalis phosphofructokinase, putative 0.0239 0.0523 0.1282
Brugia malayi Nuclear hormone receptor family member nhr-25 0.1003 0.2418 0.2418
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0105 0.0192 0.0245
Schistosoma mansoni hypothetical protein 0.3176 0.7808 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0105 0.0191 0.1872
Loa Loa (eye worm) hypothetical protein 0.0033 0.0011 0.0011
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0172 0.0357 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0046
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0333 0.0756 0.0756
Brugia malayi Immunoglobulin I-set domain containing protein 0.009 0.0155 0.0155
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0119 0.0225 0.2827
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0105 0.0191 0.2512
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0062 0.0879
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0329 0.0747 0.9977
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0216 0.3148
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.01 0.0178 0.0178
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0105 0.0191 0.0832
Trichomonas vaginalis DNA helicase recq, putative 0.0036 0.002 0.0042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.026 0.0575 0.5992
Brugia malayi Nuclear hormone receptor family member nhr-19 0.1003 0.2418 0.2418
Schistosoma mansoni kinase 0.0041 0.0032 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0119 0.0226 0.0289
Loa Loa (eye worm) cytochrome P450 family protein 0.0263 0.0582 0.0582
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0083 0.0083
Trypanosoma cruzi cysteine peptidase, putative 0.022 0.0475 0.6322
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Echinococcus granulosus survival motor neuron protein 1 0.1187 0.2874 0.3681
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.0182 0.0182
Brugia malayi Probable isocitrate dehydrogenase 0.0036 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0119 0.0225 0.2967
Schistosoma mansoni lamin 0.0417 0.0964 0.1235
Schistosoma mansoni hypothetical protein 0.0478 0.1116 0.1429
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.0191 0.0829
Loa Loa (eye worm) jmjC domain-containing protein 0.0051 0.0057 0.0057
Brugia malayi Cytochrome P450 family protein 0.0268 0.0595 0.0595
Entamoeba histolytica recQ family helicase, putative 0.0036 0.002 0.0065
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0065 0.0091 0.132
Trichomonas vaginalis alpha-glucosidase, putative 0.0074 0.0114 0.0272
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0065 0.0091 0.1427
Brugia malayi Heterochromatin protein 1 0.0087 0.0146 0.0146
Echinococcus granulosus TGF beta signal transducer SmadC 0.005 0.0056 0.0071
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0011 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0019 0.0009
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0002 0.0003
Leishmania major protein kinase, putative 0.033 0.0749 1
Echinococcus multilocularis adam 17 protease 0.0223 0.0483 0.0485
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0036 0.002 0.0025
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0411 0.0949 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0411 0.0949 0.0949
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0125 0.0125
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.003 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0114 0.147
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0083 0.0106
Mycobacterium ulcerans hydrolase 0.0411 0.0949 0.4441
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0105 0.0191 0.0832
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.0747 0.1836
Echinococcus granulosus cathepsin L cysteine protease 0.003 0.0004 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.006 0.008 0.0675
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.0015 0.0015
Onchocerca volvulus 0.0058 0.0073 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0105 0.0191 0.1872
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0114 0.0436
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0063 0.0088 0.0334
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0046
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0033 0.0479
Brugia malayi MH1 domain containing protein 0.005 0.0056 0.0056
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.0065 0.0133
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0579 0.1367 0.175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0211 0.0453 0.0581
Loa Loa (eye worm) hypothetical protein 0.1187 0.2874 0.2874
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0105 0.0191 0.1872
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.006 0.008 0.008
Echinococcus granulosus bloom syndrome protein 0.0068 0.0099 0.0127
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0053 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Brugia malayi nuclear hormone receptor 0.1003 0.2418 0.2418
Brugia malayi HSF-type DNA-binding domain containing protein 0.0073 0.0111 0.0111
Onchocerca volvulus 0.0337 0.0767 0.1867
Onchocerca volvulus 0.0473 0.1104 0.2701
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Echinococcus granulosus lysine specific demethylase 5A 0.0106 0.0194 0.0248
Echinococcus granulosus lamin dm0 0.0417 0.0964 0.1235
Loa Loa (eye worm) cysteine protease 0.0058 0.0073 0.0073
Brugia malayi nuclear receptor NHR-67 0.0473 0.1104 0.1104
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0026
Brugia malayi follicle stimulating hormone receptor 0.0282 0.063 0.063
Echinococcus granulosus FTZ F1 alpha 0.1003 0.2418 0.3097
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0019 0.0037
Echinococcus granulosus geminin 0.3176 0.7808 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0211 0.0453 0.0581
Trichomonas vaginalis CAMK family protein kinase 0.004 0.003 0.0065
Echinococcus multilocularis cpg binding protein 0.0052 0.006 0.006
Trichomonas vaginalis maltase-glucoamylase, putative 0.0074 0.0114 0.0272
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.002 0.0024
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.053 0.1245 0.1248
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0022 0.0022
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0473 0.1104 0.1104
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0105 0.0191 0.0832
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.1003 0.2418 0.2424
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0172 0.0357 0.4731
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0019 0.0219
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0211 0.0453 0.0454
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.023 0.0502 0.0503
Leishmania major cathepsin L-like protease 0.0058 0.0073 0.0751
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0063 0.0088 0.127
Echinococcus granulosus nuclear factor of activated T cells 5 0.0463 0.108 0.1383
Brugia malayi exodeoxyribonuclease III family protein 0.0119 0.0225 0.0225
Brugia malayi Importin beta-1 subunit 0.0056 0.007 0.007
Trichomonas vaginalis D-aminoacylase, putative 0.006 0.008 0.0188
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0047 0.0047 0.0047
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.1003 0.2418 0.3097
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0053 0.0467
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.006 0.008 0.0102
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0073 0.0276
Schistosoma mansoni aldehyde dehydrogenase 0.0305 0.0686 0.0879
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.0172 0.0357 0.0357
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0223 0.0483 0.0619
Loa Loa (eye worm) hypothetical protein 0.0417 0.0964 0.0964
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.008 0.013 0.1522
Brugia malayi jmjC domain containing protein 0.0152 0.0308 0.0308
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0473 0.1104 0.1107
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0019
Brugia malayi SET domain containing protein 0.0034 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.008 0.1014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.1003 0.2418 0.2424
Schistosoma mansoni zinc finger protein 0.004 0.0031 0.0039
Echinococcus granulosus cysteine protease 0.003 0.0004 0.0005
Brugia malayi 6-phosphofructokinase 0.0239 0.0523 0.0523
Trypanosoma brucei DNA polymerase IV, putative 0.0094 0.0164 0.2419
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0045 0.0043 0.0098
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.0073 0.0073
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0036 0.002 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.022 0.0475 0.7134
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.023 0.0502 0.0643
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0191 0.2504
Brugia malayi acetyltransferase, GNAT family protein 0.0613 0.145 0.145
Loa Loa (eye worm) hypothetical protein 0.0039 0.0026 0.0026
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0072 0.0109 0.0993
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0047 0.0047 0.006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0211 0.0453 0.0453
Mycobacterium tuberculosis Conserved protein 0.006 0.008 0.0675
Schistosoma mansoni ap endonuclease 0.0119 0.0225 0.0288
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0065 0.0091 0.0215
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0006 0.0007
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.0073 0.0094
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0083 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.1003 0.2418 0.2418
Brugia malayi Cathepsin L-like precursor 0.0058 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.033 0.0749 1
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0239 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0235 0.0514 0.0658
Onchocerca volvulus 0.0058 0.0073 0.0154
Brugia malayi Smad1 0.005 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0073 0.0173
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0172 0.0357 0.0357
Brugia malayi Glycosyl hydrolases family 31 protein 0.0074 0.0114 0.0114
Brugia malayi hypoxia-induced factor 1 0.3684 0.9067 0.9067
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0296 0.0664 0.0666
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.0511 0.5298
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.0191 0.2504
Loa Loa (eye worm) hypothetical protein 0.1003 0.2418 0.2418
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.01 0.0178 0.0228
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0172 0.0357 0.0872
Schistosoma mansoni aryl hydrocarbon receptor 0.121 0.2933 0.3756
Schistosoma mansoni chromodomain helicase DNA binding protein 0.003 0.0004 0.0005
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0036 0.002 0.002
Onchocerca volvulus Serine\/threonine kinase homolog 0.008 0.013 0.0293
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0022 0.0028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0074 0.0114 0.0436
Brugia malayi Uncoordinated protein 44 0.009 0.0155 0.0155
Brugia malayi Ets-domain containing protein 0.0078 0.0125 0.0125
Trypanosoma brucei glucosidase, putative 0.0074 0.0114 0.1659
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0058 0.0819
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0105 0.0191 0.0832
Echinococcus granulosus mothers against decapentaplegic 5 0.005 0.0056 0.0071
Schistosoma mansoni chromobox protein 0.0087 0.0146 0.0187
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0202 0.0431 0.0552
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0105 0.0191 0.0832
Leishmania major alpha glucosidase II subunit, putative 0.0074 0.0114 0.1301
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0182 0.0382 0.5725
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0211 0.0453 0.0581
Brugia malayi Bloom's syndrome protein homolog 0.0068 0.0099 0.0099
Brugia malayi hypothetical protein 0.1043 0.2518 0.2518
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0019 0.0009
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0105 0.0191 0.0832
Trichomonas vaginalis DNA helicase recq, putative 0.0068 0.0099 0.0235
Echinococcus granulosus aryl hydrocarbon receptor 0.0376 0.0864 0.1106
Brugia malayi hypothetical protein 0.0373 0.0857 0.0857
Loa Loa (eye worm) hypothetical protein 0.0473 0.1104 0.1104
Trypanosoma brucei polo-like protein kinase 0.008 0.013 0.1903
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0019 0.0037
Trichomonas vaginalis guanylate cyclase, putative 0.0329 0.0747 0.1836
Onchocerca volvulus Matrilysin homolog 0.0748 0.1785 0.4384
Echinococcus multilocularis isocitrate dehydrogenase 0.0296 0.0664 0.0666
Loa Loa (eye worm) hypothetical protein 0.0337 0.0767 0.0767
Trichomonas vaginalis phosphofructokinase, putative 0.0239 0.0523 0.1282
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.0015 0.0157
Echinococcus multilocularis lysosomal alpha glucosidase 0.0333 0.0756 0.0758
Loa Loa (eye worm) hypothetical protein 0.006 0.008 0.008
Echinococcus multilocularis lamin dm0 0.0417 0.0964 0.0966
Schistosoma mansoni zinc finger protein 0.0473 0.1104 0.1414
Trichomonas vaginalis CAMK family protein kinase 0.004 0.003 0.0065
Loa Loa (eye worm) matrixin family protein 0.0815 0.1952 0.1952
Echinococcus multilocularis chromobox protein 1 0.0087 0.0146 0.0146
Mycobacterium ulcerans putative regulatory protein 0.0881 0.2115 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0105 0.0191 0.1872
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0239 0.0523 0.7859
Echinococcus granulosus cathepsin l1 0.0039 0.0026 0.0034
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0063 0.0088 0.0088
Loa Loa (eye worm) TAR-binding protein 0.0119 0.0226 0.0226
Loa Loa (eye worm) fli-1 protein 0.0238 0.052 0.052
Loa Loa (eye worm) heterochromatin protein 1 0.0087 0.0146 0.0146
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0083 0.0083
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0105 0.0191 0.1872
Trichomonas vaginalis phosphofructokinase, putative 0.0065 0.0091 0.0215
Trichomonas vaginalis DNA helicase recq1, putative 0.0068 0.0099 0.0235
Loa Loa (eye worm) hypothetical protein 0.0034 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0067 0.0097 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.023 0.0502 0.0643
Entamoeba histolytica heat shock transcription factor, putative 0.0073 0.0111 0.0427
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0036 0.002 0.0246
Brugia malayi Thioredoxin reductase 0.0103 0.0185 0.0185
Echinococcus granulosus Ankyrin 0.0091 0.0157 0.0201
Mycobacterium tuberculosis Probable aminotransferase 0.0134 0.0262 0.2635
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0074 0.0114 0.0114
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0019 0.0523
Schistosoma mansoni single-minded 0.121 0.2932 0.3756
Loa Loa (eye worm) thioredoxin reductase 0.0103 0.0185 0.0185
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0034 0.0044
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0046
Trypanosoma cruzi cysteine peptidase, putative 0.022 0.0475 0.6322
Brugia malayi MAP kinase sur-1 0.0049 0.0053 0.0053
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0033 0.0033
Leishmania major tyrosine aminotransferase 0.019 0.0401 0.5237
Schistosoma mansoni hypothetical protein 0.0242 0.0531 0.068
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.0511 0.5298
Loa Loa (eye worm) hypothetical protein 0.0124 0.0239 0.0239
Onchocerca volvulus 0.006 0.008 0.0169
Trypanosoma cruzi major cysteine proteinase, putative 0.0173 0.0359 0.4757
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0473 0.1104 0.2701
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.1003 0.2418 0.2418
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0019 0.0037
Echinococcus granulosus Smad4 0.005 0.0056 0.0071
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0105 0.0191 0.0832
Schistosoma mansoni Tr4/Tr2 (homologue) 0.1003 0.2418 0.3097
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0239 0.0523 0.5417
Brugia malayi nuclear receptor NHR-88 0.1003 0.2418 0.2418
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0026 0.0056
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0065 0.0091 0.0344
Trichomonas vaginalis glutamine synthetase, putative 0.0035 0.0017 0.0033
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0263 0.0583 0.0583
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0105 0.0191 0.0832
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0065 0.0091 0.0987
Brugia malayi Pre-SET motif family protein 0.1461 0.3554 0.3554
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0019 0.0272
Echinococcus granulosus microtubule associated protein 2 0.0664 0.1577 0.202
Plasmodium vivax thioredoxin reductase, putative 0.0103 0.0185 0.2736
Brugia malayi Matrixin family protein 0.0815 0.1952 0.1952
Loa Loa (eye worm) latrophilin receptor protein 2 0.0092 0.016 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0058 0.0073 0.0173
Trichomonas vaginalis sucrase-isomaltase, putative 0.0074 0.0114 0.0272
Echinococcus granulosus glutamine synthetase 0.0138 0.0272 0.0349
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.1003 0.2418 0.2418
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0105 0.0191 0.0832
Schistosoma mansoni smad1 5 8 and 0.005 0.0056 0.0071
Echinococcus multilocularis cathepsin L cysteine protease 0.0058 0.0073 0.0074
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0053 0.0652
Brugia malayi Cathepsin L-like cysteine proteinase 0.0039 0.0026 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0239 0.0523 0.1282
Echinococcus granulosus adam 0.0039 0.0027 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.0073 0.0173
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0242 0.0531 0.0531
Schistosoma mansoni retinoic acid receptor RXR 0.1003 0.2418 0.3097
Echinococcus multilocularis cysteine protease 0.0058 0.0073 0.0074
Brugia malayi hypothetical protein 0.0047 0.0047 0.0047
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0036 0.002 0.002
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0201 0.0429 0.043
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.001 0.0012
Leishmania major DNA polymerase eta, putative 0.0061 0.0083 0.0874
Trichomonas vaginalis ran, putative 0.0041 0.0033 0.0072
Toxoplasma gondii glutamine synthetase, type I, putative 0.0089 0.015 0.2192
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0211 0.0453 0.0581
Echinococcus granulosus netrin receptor unc 5 0.009 0.0155 0.0198
Mycobacterium ulcerans beta-lactamase 0.006 0.008 0.03
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0268 0.0595 0.2756
Plasmodium falciparum importin beta, putative 0.0056 0.007 0.1048
Echinococcus multilocularis neuropeptide receptor A26 0.2198 0.5381 0.5394
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0119 0.0225 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0073 0.0073
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0105 0.0191 0.0832
Echinococcus granulosus cathepsin l cysteine peptidase 0.0058 0.0073 0.0094
Onchocerca volvulus 0.1663 0.4056 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0119 0.0225 0.0226
Mycobacterium ulcerans hypothetical protein 0.006 0.008 0.03
Brugia malayi cytochrome P450 0.0105 0.0191 0.0191
Leishmania major cathepsin L-like protease 0.0058 0.0073 0.0751
Schistosoma mansoni hypothetical protein 0.0374 0.0857 0.1098
Mycobacterium tuberculosis Conserved protein 0.006 0.008 0.0675
Echinococcus granulosus peregrin 0.0042 0.0036 0.0046
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.1003 0.2418 0.3097
Echinococcus granulosus importin subunit beta 1 0.0056 0.007 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.0191 0.2826
Echinococcus multilocularis muscleblind protein 1 0.0296 0.0666 0.0667
Toxoplasma gondii thioredoxin reductase 0.0103 0.0185 0.2693
Schistosoma mansoni cpg binding protein 0.0052 0.006 0.0077
Loa Loa (eye worm) steroid hormone receptor 0.1003 0.2418 0.2418
Echinococcus granulosus chromobox protein 1 0.0087 0.0146 0.0187
Leishmania major hypothetical protein, conserved 0.0051 0.0058 0.0542
Schistosoma mansoni hypothetical protein 0.0092 0.016 0.0205
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0058 0.0073 0.1106
Brugia malayi Matrixin family protein 0.0337 0.0767 0.0767
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0263 0.0583 0.2696
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0119 0.0226 0.0226
Mycobacterium ulcerans hypothetical protein 0.0134 0.0262 0.117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0019 0.0194
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0105 0.0191 0.1872
Trichomonas vaginalis penicillin-binding protein, putative 0.006 0.008 0.0188
Echinococcus granulosus Nuclear hormone receptor HR96 0.0473 0.1104 0.1414
Plasmodium vivax hypothetical protein, conserved 0.006 0.008 0.1145
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0105 0.0191 0.2512
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0172 0.0357 0.0357
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0074 0.0114 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0006 0.0007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0019 0.0194
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0046 0.0044 0.0608
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0296 0.0664 0.0851
Trichomonas vaginalis phosphofructokinase, putative 0.0239 0.0523 0.1282
Loa Loa (eye worm) hypothetical protein 0.0091 0.0157 0.0157
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0263 0.0583 0.6071
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.026 0.0575 0.5992
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0036 0.002 0.0013
Entamoeba histolytica hypothetical protein 0.1043 0.2518 1
Schistosoma mansoni unc-13 (munc13) 0.0036 0.002 0.0025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0296 0.0664 0.8838
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.014 0.0277 0.0355
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.1003 0.2418 0.2418
Trypanosoma brucei DNA polymerase kappa, putative 0.0053 0.0062 0.0879
Onchocerca volvulus Cathepsin L homolog 0.0058 0.0073 0.0154
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0263 0.0583 0.0746
Loa Loa (eye worm) hypothetical protein 0.0092 0.016 0.016
Trypanosoma cruzi tyrosine aminotransferase 0.019 0.0401 0.533
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0473 0.1104 0.1104
Loa Loa (eye worm) hypothetical protein 0.053 0.1245 0.1245
Leishmania major GTP-binding protein, putative 0.0041 0.0033 0.0195
Loa Loa (eye worm) matrixin family protein 0.0748 0.1785 0.1785
Trypanosoma cruzi glutamine synthetase, putative 0.0138 0.0272 0.3601
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.003 0.0004 0.0004
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.006 0.008 0.03
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0019 0.0219
Schistosoma mansoni steroid hormone receptor ad4bp 0.1003 0.2418 0.3097
Schistosoma mansoni 6-phosphofructokinase 0.0239 0.0523 0.067
Onchocerca volvulus 0.0376 0.0863 0.2106
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0125 0.016
Trypanosoma cruzi tyrosine aminotransferase 0.019 0.0401 0.533

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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