Detailed information for compound 2075861

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 468.43 | Formula: C20H23F3N6O4
  • H donors: 3 H acceptors: 6 LogP: -1.48 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.O=C1NCCN(C1)C(=O)c1n[nH]c2c1CN(CC2)Cc1cccc(n1)C
  • InChi: 1S/C18H22N6O2.C2HF3O2/c1-12-3-2-4-13(20-12)9-23-7-5-15-14(10-23)17(22-21-15)18(26)24-8-6-19-16(25)11-24;3-2(4,5)1(6)7/h2-4H,5-11H2,1H3,(H,19,25)(H,21,22);(H,6,7)
  • InChiKey: HXQMHVXSDRUVFS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0366 0.0488
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0688 0.7006 0.7006
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0037 0.0293 0.0391
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.012 0.1147 0.153
Onchocerca volvulus 0.0013 0.0049 0.0046
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Plasmodium vivax replication factor C subunit 1, putative 0.0012 0.0039 0.0519
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0012 0.0039 0.00000049621
Echinococcus multilocularis thioredoxin glutathione reductase 0.0023 0.0158 0.0158
Brugia malayi Cytochrome P450 family protein 0.0037 0.0295 0.0394
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Brugia malayi Dopamine receptor protein 1 0.0013 0.0049 0.0066
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0037 0.0293 0.085
Trichomonas vaginalis adenosine diphosphatase, putative 0.0022 0.0139 0.0198
Brugia malayi Serotonin receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0032 0.0246 0.0307
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.1066
Onchocerca volvulus 0.0013 0.0049 0.0046
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.012 0.1147 0.153
Brugia malayi Inositol-1 0.0045 0.0376 0.0501
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0033 0.0254 0.2904
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0013 0.0049 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0046 0.0061
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0049 0.0049
Echinococcus multilocularis geminin 0.0205 0.2023 0.2023
Trypanosoma brucei unspecified product 0.012 0.1147 0.153
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0059 0.0529 0.6607
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0254 0.0339
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0037 0.0293 0.0391
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Onchocerca volvulus 0.0033 0.0252 0.0336
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0046 0.0061
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.058 0.0754
Loa Loa (eye worm) Smad1 0.0027 0.0199 0.0245
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0049 0.0066
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0364 0.0485
Leishmania major trypanothione reductase 0.0023 0.0158 0.021
Loa Loa (eye worm) hypothetical protein 0.0058 0.0518 0.0671
Trypanosoma brucei nucleoside transporter 1, putative 0.012 0.1147 0.153
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0112 0.015
Giardia lamblia Replication factor C, subunit 1 0.0012 0.0039 0.0055
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 1
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0081 0.0747 0.0747
Trypanosoma brucei adenosine transporter 2, putative 0.012 0.1147 0.153
Toxoplasma gondii nucleoside transporter protein 0.012 0.1147 0.153
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.2857 0.2857
Onchocerca volvulus Putative pyridoxal kinase 0.0084 0.078 0.1092
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Mycobacterium tuberculosis Probable reductase 0.0053 0.0467 0.1354
Brugia malayi TAR-binding protein 0.0064 0.058 0.0774
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0688 0.7006 0.7006
Brugia malayi Dopamine receptor protein 2 0.0013 0.0049 0.0066
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0022 0.0139 0.0198
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 1
Trichomonas vaginalis DNA helicase recq, putative 0.001 0.0016 0.0023
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0096 0.0107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Toxoplasma gondii Nucleoside-diphosphatase 0.0022 0.0139 0.0185
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0081 0.0747 0.0996
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0039 0.0055
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni hypothetical protein 0.0205 0.2023 0.2699
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Schistosoma mansoni intermediate filament proteins 0.0033 0.0252 0.0336
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0017 0.0087 0.0117
Brugia malayi topoisomerase 0.0012 0.0039 0.0052
Schistosoma mansoni lamin 0.0033 0.0252 0.0336
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0049 0.0049
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0663 0.674 0.8991
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0663 0.674 0.9622
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0084 0.078 0.1041
Brugia malayi mothers against decapentaplegic homolog 3 0.0012 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus granulosus lamin dm0 0.0033 0.0252 0.0336
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0169
Echinococcus granulosus neuropeptide s receptor 0.0013 0.0049 0.0066
Schistosoma mansoni alpha-glucosidase 0.0169 0.166 0.2214
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0169
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0013 0.0046 0.0061
Trichomonas vaginalis ribokinase, putative 0.0084 0.078 0.1114
Plasmodium falciparum apyrase, putative 0.0022 0.0139 0.186
Loa Loa (eye worm) inositol-1 0.0045 0.0376 0.0481
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0013 0.0049 0.0066
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0084 0.012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0169
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0049 0.0049
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0688 0.7006 1
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0039 0.0052
Onchocerca volvulus 0.0012 0.0039 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0252 0.0315
Leishmania major hypothetical protein, conserved 0.0081 0.0747 0.0996
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0663 0.674 0.8991
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0081 0.0747 0.0977
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0084 0.0096
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0049 0.0049
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0084 0.0065
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0013 0.0049 0.0044
Trypanosoma brucei adenosine transporter 2, putative 0.012 0.1147 0.153
Trypanosoma brucei purine nucleoside transporter 0.012 0.1147 0.153
Trypanosoma brucei adenosine transporter, putative 0.012 0.1147 0.153
Plasmodium falciparum replication factor C subunit 1, putative 0.0012 0.0039 0.0519
Schistosoma mansoni adenosine diphosphatase 0.0033 0.0254 0.0339
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0013 0.0049 0.0066
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0017 0.0087 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0033 0.0254 0.0309
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0037 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Brugia malayi ORL1-like opioid receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0049 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0117
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.2857 0.3811
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0364 0.0485
Entamoeba histolytica hypothetical protein 0.0043 0.0364 0.0466
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0013 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0169
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0037 0.0293 0.3927
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0366 0.0488
Onchocerca volvulus 0.0013 0.0049 0.0046
Schistosoma mansoni guanosine-diphosphatase 0.0022 0.0139 0.0185
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0013 0.0046 0.0133
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0143 0.0413
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0017 0.0087 0.0117
Echinococcus granulosus serotonin receptor 0.0013 0.0049 0.0066
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.0017 0.0023
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0199 0.0245
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.001 0.0019 0.0026
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0017 0.0017
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0033 0.0254 0.0318
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Schistosoma mansoni Smad4 0.0012 0.0043 0.0057
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0046 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus granulosus sex peptide receptor 0.0013 0.0049 0.0066
Schistosoma mansoni biogenic amine receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0084 0.0112
Schistosoma mansoni Smad4 0.0027 0.0199 0.0266
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0366 0.0522
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0049 0.0044
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0081 0.0747 0.0996
Plasmodium falciparum phosphodiesterase delta, putative 0.0081 0.0747 1
Mycobacterium ulcerans acetyl-CoA synthetase 0.0013 0.0046 0.0133
Echinococcus granulosus nibrin 0.0012 0.0039 0.0052
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0125 0.0361
Toxoplasma gondii thioredoxin reductase 0.0023 0.0158 0.021
Loa Loa (eye worm) TYRA-2 protein 0.0013 0.0049 0.0044
Echinococcus granulosus geminin 0.0205 0.2023 0.2699
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Plasmodium vivax glutathione reductase, putative 0.0023 0.0158 0.2112
Echinococcus multilocularis musashi 0.0033 0.0252 0.0252
Toxoplasma gondii isocitrate dehydrogenase 0.0037 0.0293 0.0391
Trypanosoma brucei endonuclease G, putative 0.001 0.0019 0.0026
Schistosoma mansoni growth hormone secretagogue receptor 0.0013 0.0049 0.0066
Leishmania major putative PfkB family sugar kinase 0.0084 0.078 0.1041
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.012 0.1147 0.1638
Echinococcus granulosus somatostatin receptor 0.0013 0.0049 0.0066
Onchocerca volvulus 0.0013 0.0049 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0049 0.0066
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Plasmodium vivax acetyl-CoA synthetase, putative 0.0013 0.0046 0.0613
Echinococcus multilocularis allatostatin A receptor 0.0013 0.0049 0.0049
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0081 0.0747 0.0996
Schistosoma mansoni amine GPCR 0.0013 0.0049 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0022 0.0139 0.0185
Brugia malayi Thioredoxin reductase 0.0023 0.0158 0.021
Echinococcus multilocularis orexin receptor type 2 0.0013 0.0049 0.0049
Trichomonas vaginalis ribokinase, putative 0.0084 0.078 0.1114
Onchocerca volvulus Neuropeptide F receptor homolog 0.0013 0.0049 0.0046
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0366 0.0522
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0049 0.0049
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 1
Onchocerca volvulus 0.0017 0.0087 0.0101
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0582 0.591 0.7878
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Entamoeba histolytica hypothetical protein 0.0043 0.0364 0.0466
Schistosoma mansoni tar DNA-binding protein 0.0064 0.058 0.0774
Plasmodium vivax acyl-CoA synthetase, putative 0.0022 0.0143 0.1909
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Onchocerca volvulus 0.0013 0.0049 0.0046
Schistosoma mansoni neuropeptide f receptor 76f 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0095
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0081 0.0747 0.0996
Trypanosoma brucei endonuclease G, putative 0.001 0.0019 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0049 0.0066
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0043 0.0036
Onchocerca volvulus 0.0013 0.0049 0.0046
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0049 0.0066
Schistosoma mansoni hypothetical protein 0.0013 0.0049 0.0066
Echinococcus granulosus hypothetical protein 0.0013 0.0049 0.0066
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0081 0.0747 0.0996
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0199 0.0199
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0016 0.0083 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0254 0.0339
Onchocerca volvulus 0.0013 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0075
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0254 0.0339
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0046 0.0133
Leishmania major tagatose-6-phosphate kinase-like protein 0.0084 0.078 0.1041
Leishmania major acetyl-CoA synthetase, putative 0.0013 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Brugia malayi RE15519p 0.0013 0.0049 0.0066
Onchocerca volvulus 0.0013 0.0046 0.0041
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Trypanosoma brucei nucleoside diphosphatase, putative 0.0033 0.0254 0.0339
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.012 0.1147 0.1638
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0139
Trypanosoma cruzi adenosine kinase, putative 0.0736 0.7497 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0087 0.0124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0056 0.0494 0.0639
Trypanosoma brucei ribokinase, putative 0.0084 0.078 0.1041
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0076
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0013 0.0049 0.0049
Brugia malayi hypothetical protein 0.0688 0.7006 0.9344
Toxoplasma gondii ATPase, AAA family protein 0.0012 0.0039 0.0052
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0022 0.0143 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0046 0.0133
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis ectonucleotide 0.0014 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0688 0.7006 0.9343
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Echinococcus multilocularis ribokinase 0.0084 0.078 0.078
Echinococcus multilocularis lamin 0.0033 0.0252 0.0252
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0376 1
Brugia malayi G-protein coupled receptor 0.0013 0.0049 0.0066
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0013 0.0046 0.0133
Toxoplasma gondii propionate-CoA ligase 0.0013 0.0046 0.0061
Schistosoma mansoni hypothetical protein 0.0026 0.0186 0.0248
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus multilocularis GPCR, family 2 0.0019 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0112 0.0129
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0376 0.0536
Echinococcus granulosus neuropeptide receptor A26 0.0013 0.0049 0.0066
Schistosoma mansoni endonuclease related 0.001 0.0019 0.0026
Echinococcus granulosus Endonuclease G 0.001 0.0019 0.0026
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0013 0.0049 0.0066
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0037 0.0293 0.0391
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0582 0.591 0.7883
Trypanosoma cruzi endonuclease G, putative 0.001 0.0019 0.0026
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.0996
Trypanosoma brucei PAB1-binding protein , putative 0.0058 0.0518 0.0691
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0049 0.0049
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0688 0.7006 1
Schistosoma mansoni hypothetical protein 0.001 0.0017 0.0023
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0112 0.0129
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0117
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0081 0.0747 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0013 0.0049 0.0044
Schistosoma mansoni amine GPCR 0.0013 0.0049 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Loa Loa (eye worm) oxidoreductase 0.0013 0.0046 0.004
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.012 0.1147 0.1638
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0017 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0064 0.058 0.0774
Leishmania major hypothetical protein, conserved 0.0081 0.0747 0.0996
Trichomonas vaginalis adenosine diphosphatase, putative 0.0022 0.0139 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0747 0.1066
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0046 0.0061
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0013 0.0046 0.0133
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0081 0.0747 0.0996
Brugia malayi MH2 domain containing protein 0.0404 0.4072 0.5432
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0013 0.0046 0.0133
Trypanosoma brucei adenosine transporter, putative 0.012 0.1147 0.153
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0376 0.0536
Schistosoma mansoni opsin-like receptor 0.0013 0.0049 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.0254 0.0318
Schistosoma mansoni inositol monophosphatase 0.0045 0.0376 0.0501
Schistosoma mansoni acetyl-CoA synthetase 0.0013 0.0046 0.0061
Brugia malayi Adenosine kinase-like 0.0736 0.7497 1
Schistosoma mansoni polycystin 1-related 0.001 0.0017 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.0747 0.0996
Brugia malayi Thrombospondin type 1 domain containing protein 0.0036 0.0286 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0139 0.0198
Loa Loa (eye worm) hypothetical protein 0.0148 0.144 0.1903
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni smad1 5 8 and 0.0027 0.0199 0.0266
Echinococcus granulosus expressed protein 0.0017 0.0087 0.0116
Echinococcus multilocularis somatostatin receptor 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0081 0.0747 0.0977
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.012 0.1147 0.1638
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0039 0.0055
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.012 0.1147 0.153
Trypanosoma brucei nucleoside transporter 1, putative 0.012 0.1147 0.153
Brugia malayi Dopamine receptor 0.0013 0.0049 0.0066
Echinococcus granulosus G protein coupled receptor 139 0.0013 0.0049 0.0066
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0056 0.0494 0.0659
Trypanosoma brucei glucosidase, putative 0.0044 0.0366 0.0488
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0013 0.0049 0.0049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Loa Loa (eye worm) hypothetical protein 0.0041 0.034 0.0433
Trypanosoma cruzi FHA domain containing protein, putative 0.0012 0.0039 0.0052
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0049 0.0066
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Plasmodium vivax thioredoxin reductase, putative 0.0023 0.0158 0.2112
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0084 0.078 0.2262
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0049 0.0066
Trypanosoma cruzi ribokinase, putative 0.0084 0.078 0.1041
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.0022 0.0139 0.0198
Brugia malayi Melatonin receptor type 1A 0.0013 0.0049 0.0066
Echinococcus granulosus g protein coupled receptor 0.0013 0.0049 0.0066
Leishmania major endonuclease G, putative 0.001 0.0019 0.0026
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0049 0.0049
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0037 0.0293 0.0391
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0117
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0112 0.015
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0013 0.0046 0.0133
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0013 0.0046 0.0133
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0039 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0084 0.012
Schistosoma mansoni rotamase 0.0017 0.0087 0.0116
Brugia malayi hypothetical protein 0.001 0.0017 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0254 0.0737
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0081 0.0747 0.0996
Entamoeba histolytica acyl-coA synthetase, putative 0.0033 0.0254 0.0309
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0013 0.0046 0.0613
Trypanosoma cruzi nucleobase transporter, putative 0.012 0.1147 0.153
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Trypanosoma cruzi nucleoside transporter-like, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0185
Brugia malayi Ribokinase 0.0084 0.078 0.1041
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0053 0.0467 0.5778
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.0017 0.0228
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0012 0.0039 0.1032
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0017 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0536 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus multilocularis adenosine kinase 0.0736 0.7497 0.7497
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0112 0.015
Loa Loa (eye worm) nuclear factor I 0.0015 0.0073 0.0076
Brugia malayi Smad1 0.0027 0.0199 0.0266
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus multilocularis Smad4 0.0027 0.0199 0.0199
Echinococcus multilocularis nibrin 0.0012 0.0039 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Schistosoma mansoni survival motor neuron protein 0.0058 0.0516 0.0688
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0081 0.0747 0.0747
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0013 0.0049 0.0049
Onchocerca volvulus 0.0013 0.0049 0.0046
Loa Loa (eye worm) isocitrate dehydrogenase 0.0037 0.0293 0.0371
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0327 0.095
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0366 0.0522
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0013 0.0046 0.0095
Schistosoma mansoni adenoreceptor 0.0013 0.0049 0.0066
Echinococcus granulosus mothers against decapentaplegic 6 0.0012 0.0043 0.0057
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.001 0.0019 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0366 0.0522
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni biogenic amine receptor 0.0013 0.0049 0.0066
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0286 0.2857 0.3797
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0095
Giardia lamblia Hypothetical protein 0.0081 0.0747 0.1066
Schistosoma mansoni alpha-1 adrenergic receptor 0.0013 0.0049 0.0066
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0046 0.0061
Schistosoma mansoni tar DNA-binding protein 0.0064 0.058 0.0774
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0059 0.0529 0.1533
Onchocerca volvulus 0.0017 0.0087 0.0101
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.058 0.0774
Leishmania major cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0033 0.0254 0.0339
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0081 0.0747 0.0747
Trypanosoma cruzi adenosine kinase, putative 0.0084 0.078 0.1041
Trichomonas vaginalis DNA helicase recq1, putative 0.001 0.0016 0.0023
Brugia malayi RNA binding protein 0.0064 0.058 0.0774
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0016 0.0083 0.0111
Plasmodium falciparum thioredoxin reductase 0.0023 0.0158 0.2112
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0049 0.0066
Onchocerca volvulus 0.0033 0.0252 0.0336
Brugia malayi MH1 domain containing protein 0.0015 0.0073 0.0097
Schistosoma mansoni smad 0.0027 0.0199 0.0266
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0013 0.0046 0.0133
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Loa Loa (eye worm) doublecortin family protein 0.001 0.0017 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0084 0.012
Echinococcus multilocularis lamin dm0 0.0033 0.0252 0.0252
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trypanosoma brucei endonuclease G, putative 0.001 0.0019 0.0026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0199 0.0266
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Schistosoma mansoni myosin xvIII 0.0013 0.0049 0.0066
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0013 0.0049 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0197 0.1942 0.2575
Giardia lamblia Ribokinase 0.0084 0.078 0.1114
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0053 0.0467 0.1354
Schistosoma mansoni opsin-like receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0084 0.078 0.1021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0049 0.0049
Brugia malayi intermediate filament protein 0.0033 0.0252 0.0336
Onchocerca volvulus 0.0013 0.0049 0.0046
Echinococcus granulosus intermediate filament protein 0.0033 0.0252 0.0336
Schistosoma mansoni hypothetical protein 0.0043 0.0364 0.0485
Entamoeba histolytica ribokinase, putative 0.0084 0.078 0.1064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0095
Schistosoma mansoni hypothetical protein 0.0205 0.2023 0.2699
Trichomonas vaginalis adenosine diphosphatase, putative 0.0022 0.0139 0.0198
Entamoeba histolytica hypothetical protein 0.0043 0.0364 0.0466
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0013 0.0049 0.0066
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0081 0.0747 0.0996
Trichomonas vaginalis rotamase, putative 0.0017 0.0087 0.0124
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0366 0.0366
Schistosoma mansoni hypothetical protein 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0081 0.0747 0.0747
Schistosoma mansoni tar DNA-binding protein 0.0064 0.058 0.0774
Echinococcus granulosus fmrfamide receptor 0.0013 0.0049 0.0066
Schistosoma mansoni opsin-like receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.012 0.1147 0.153
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0688 0.7006 1
Echinococcus granulosus adenosine kinase 0.0736 0.7497 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Onchocerca volvulus 0.0033 0.0254 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0125 0.0361
Toxoplasma gondii NTPase II 0.0022 0.0139 0.0185
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.0017 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0049 0.0066
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0013 0.0049 0.0066
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Schistosoma mansoni rab6-interacting 0.001 0.0017 0.0023
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Schistosoma mansoni Smad4 0.0012 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.012 0.1147 0.1638
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0023 0.0158 0.0457
Brugia malayi MH1 domain containing protein 0.0027 0.0199 0.0266
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0022 0.0139 0.0198
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0056 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Schistosoma mansoni alpha-glucosidase 0.0169 0.166 0.2214
Echinococcus granulosus mothers against decapentaplegic 2 0.0012 0.0043 0.0057
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.001 0.0019 0.0026
Mycobacterium ulcerans fructokinase, PfkB 0.0084 0.078 0.2262
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0046 0.0065
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0013 0.0046 0.0095
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0084 0.0112
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0014 0.0061 0.0059
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0013 0.0049 0.0066
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0012 0.0039 0.0055
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0084 0.078 0.1064
Leishmania major nucleobase transporter 0.012 0.1147 0.153
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0049 0.0066
Brugia malayi hypothetical protein 0.0286 0.2857 0.3811
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni alpha glucosidase 0.0044 0.0366 0.0488
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0049 0.0066
Plasmodium vivax ataxin-2 like protein, putative 0.0058 0.0518 0.6932
Onchocerca volvulus Huntingtin homolog 0.0148 0.144 0.2036
Entamoeba histolytica nucleoside transporter, putative 0.012 0.1147 0.1591
Trypanosoma cruzi nucleobase transporter, putative 0.012 0.1147 0.153
Schistosoma mansoni guanosine-diphosphatase 0.0022 0.0139 0.0185
Schistosoma mansoni ATP-diphosphohydrolase 1 0.0022 0.0139 0.0185
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0011 0.0028 0.0081
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0197 0.1942 0.2591
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.0158 0.021
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0081 0.0747 0.0747
Trypanosoma brucei purine nucleoside transporter 0.012 0.1147 0.153
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 1
Schistosoma mansoni protein kinase 0.012 0.1147 0.153
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus granulosus peptide allatostatin:somatostatin 0.0013 0.0049 0.0066
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0017 0.0087 0.0117
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Schistosoma mansoni amine GPCR 0.0013 0.0049 0.0066
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0013 0.0049 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Brugia malayi G protein-coupled receptor F59B2.13 0.0013 0.0049 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0056 0.0494 0.0659
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0536 0.0695
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0084 0.012
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0376 0.0484
Trypanosoma brucei ribokinase, putative 0.0084 0.078 0.1041
Loa Loa (eye worm) MH2 domain-containing protein 0.0404 0.4072 0.5422
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0014 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.012 0.1147 0.1512
Schistosoma mansoni hypothetical protein 0.0036 0.0286 0.0381
Trypanosoma cruzi nucleoside transporter 1, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0039 0.0055
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0046 0.0061
Trypanosoma brucei adenosine transporter 2 0.012 0.1147 0.153
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0081 0.0747 1
Echinococcus granulosus neuropeptide receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0039 0.0052
Onchocerca volvulus 0.0013 0.0049 0.0046
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Schistosoma mansoni topbp1 0.0012 0.0039 0.0052
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0516 0.0688
Schistosoma mansoni chromosome transmission fidelity factor 0.0012 0.0039 0.0052
Schistosoma mansoni hypothetical protein 0.0041 0.034 0.0454
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0081 0.0747 0.0996
Echinococcus multilocularis serotonin receptor 0.0013 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0039 0.0055
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0049 0.0049
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0013 0.0049 0.0044
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0112 0.015
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0013 0.0049 0.0066
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0012 0.0039 0.0052
Echinococcus granulosus g-protein coupled receptor 0.0013 0.0049 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0747 0.1066
Trypanosoma brucei adenosine transporter 2, putative 0.012 0.1147 0.153
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0081 0.0747 0.0996
Schistosoma mansoni inositol monophosphatase 0.0045 0.0376 0.0501
Mycobacterium leprae Probable adenosine kinase adk 0.0084 0.078 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma brucei trypanothione reductase 0.0023 0.0158 0.021
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0046 0.0133
Schistosoma mansoni tar DNA-binding protein 0.0064 0.058 0.0774
Trypanosoma cruzi nucleobase transporter, putative 0.012 0.1147 0.153
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus multilocularis g-protein coupled receptor 0.0013 0.0049 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Entamoeba histolytica nucleoside transporter, putative 0.0688 0.7006 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0366 0.0488
Brugia malayi MH2 domain containing protein 0.0012 0.0043 0.0057
Brugia malayi GnHR receptor homolog 0.0013 0.0049 0.0066
Loa Loa (eye worm) MH2 domain-containing protein 0.0012 0.0043 0.0036
Echinococcus multilocularis isocitrate dehydrogenase 0.0037 0.0293 0.0293
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0056 0.0494 0.0659
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.1942 0.1942
Loa Loa (eye worm) TAR-binding protein 0.0064 0.058 0.0754
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0688 0.7006 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0059 0.0529 0.1533
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Echinococcus granulosus equilibrative nucleoside transporter 0.0688 0.7006 0.9344
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0343 0.3449 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0033 0.0254 0.0309
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0049 0.0066
Echinococcus granulosus g protein coupled receptor 0.0013 0.0049 0.0066
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Echinococcus granulosus allatostatin A receptor 0.0013 0.0049 0.0066
Trypanosoma cruzi nucleoside transporter 1, putative 0.012 0.1147 0.153
Onchocerca volvulus 0.0013 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0747 0.1066
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0017 0.0087 0.0116
Onchocerca volvulus 0.0013 0.0049 0.0046
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0376 0.0501
Loa Loa (eye worm) hypothetical protein 0.006 0.0536 0.0695
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0518 0.6932
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0013 0.0046 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0039 0.0055
Brugia malayi hypothetical protein 0.0012 0.0039 0.0052
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0049 0.0044
Brugia malayi MH1 domain containing protein 0.0027 0.0199 0.0266
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0254 0.0737
Loa Loa (eye worm) PDE1B protein 0.0081 0.0747 0.0977
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0252 0.0315
Echinococcus multilocularis G-protein coupled receptor, putative 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Leishmania major ATP diphosphohydrolase 0.0033 0.0254 0.0339
Brugia malayi hypothetical protein 0.0084 0.078 0.1041
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0688 0.7006 0.9344
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0013 0.0049 0.0049
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0013 0.0046 0.0133
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0366 0.0468
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0036 0.0286 0.036
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0053 0.0467 0.1354
Mycobacterium ulcerans hypothetical protein 0.0033 0.0254 0.0737
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0013 0.0049 0.0066
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0081 0.0747 0.0996
Trichomonas vaginalis rotamase, putative 0.0016 0.0083 0.0118
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0117
Trypanosoma brucei adenosine kinase, putative 0.0736 0.7497 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0013 0.0049 0.0066
Brugia malayi glutathione reductase 0.0023 0.0158 0.021
Brugia malayi follicle stimulating hormone receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0013 0.0049 0.0049
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0081 0.0747 0.0996
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0366 0.0488
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0033 0.0254 0.0737
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0037 0.0293 0.0391
Brugia malayi Bloom's syndrome protein homolog 0.001 0.0016 0.0022
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0017 0.0087 0.0117
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0663 0.674 0.8991
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0084 0.078 0.2262
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Trypanosoma cruzi nucleoside transporter 1, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Plasmodium vivax phosphodiesterase gamma, putative 0.0081 0.0747 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.144 0.1903
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0056 0.0494 0.0659
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni hypothetical protein 0.0019 0.0112 0.015
Brugia malayi larval opioid receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.034 0.0454
Echinococcus multilocularis replication factor c subunit 1 0.0012 0.0039 0.0039
Echinococcus granulosus Smad4 0.0027 0.0199 0.0266
Brugia malayi neuropeptide F receptor 0.0013 0.0049 0.0066
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0012 0.0039 0.0052
Trypanosoma brucei nucleoside phosphatase, putative 0.0033 0.0254 0.0339
Schistosoma mansoni neuropeptide receptor 0.0013 0.0049 0.0066
Onchocerca volvulus 0.0114 0.1088 0.1533
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0027 0.0198 0.0198
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0084 0.012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0078 0.0078
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0013 0.0046 0.0095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0376 0.0501
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0013 0.0049 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Schistosoma mansoni biogenic amine receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0139
Schistosoma mansoni lipoxygenase 0.0027 0.0198 0.0264
Onchocerca volvulus 0.0013 0.0049 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Schistosoma mansoni hypothetical protein 0.0013 0.0049 0.0066
Trichomonas vaginalis adenosine diphosphatase, putative 0.0022 0.0139 0.0198
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0254 0.0339
Echinococcus granulosus tar DNA binding protein 0.0064 0.058 0.0774
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0199 0.0266
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0663 0.674 0.674
Echinococcus granulosus replication factor c subunit 1 0.0012 0.0039 0.0052
Schistosoma mansoni smad1 5 8 and 0.0027 0.0199 0.0266
Loa Loa (eye worm) hypothetical protein 0.0081 0.0747 0.0977
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0081 0.0747 0.0996
Leishmania major adenosine kinase-like protein 0.0084 0.078 0.1041
Brugia malayi MH2 domain containing protein 0.0027 0.0199 0.0266
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0376 0.0536
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0081 0.0747 0.0996
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0012 0.0043 0.0037
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0037 0.0293 0.0391
Schistosoma mansoni adenosine kinase 0.0736 0.7497 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0254 0.0737
Giardia lamblia Hypothetical protein 0.0688 0.7006 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0582 0.591 0.591
Schistosoma mansoni smad 0.0012 0.0043 0.0057
Trypanosoma brucei adenosine kinase, putative 0.0736 0.7497 1
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0081 0.0747 0.0977
Brugia malayi hypothetical protein 0.0012 0.0039 0.0052
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0252 0.0315
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0037 0.0293 0.0293
Leishmania major ribokinase, putative 0.0084 0.078 0.1041
Brugia malayi DKFZp564C0469 protein 0.0012 0.0039 0.0052
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0199 0.0245
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0081 0.0747 0.0996
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0013 0.0046 0.0133
Schistosoma mansoni neuropeptide receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Echinococcus granulosus alpha 1A adrenergic receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0295 0.0373
Loa Loa (eye worm) hypothetical protein 0.0736 0.7497 1
Schistosoma mansoni neuropeptide receptor 0.0013 0.0049 0.0066
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0033 0.0254 0.2904
Onchocerca volvulus 0.0013 0.0049 0.0046
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0014 0.0061 0.0081
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0343 0.3449 1
Trypanosoma cruzi nucleoside phosphatase, putative 0.0022 0.0139 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0747 0.0996
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0033 0.0254 0.0737
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0037 0.0293 0.0293
Onchocerca volvulus 0.0013 0.0049 0.0046
Schistosoma mansoni loxhd1 0.001 0.0017 0.0023
Toxoplasma gondii kinase, pfkB family protein 0.0084 0.078 0.1041
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0013 0.0046 0.004
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0049 0.0049
Brugia malayi neuropeptide F receptor 0.0013 0.0049 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0033 0.0254 0.0737
Treponema pallidum DNA ligase (lig) 0.0012 0.0039 1
Schistosoma mansoni DNA ligase IV 0.0012 0.0039 0.0052
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0081 0.0747 0.0996
Schistosoma mansoni histamine h1 receptor 0.0013 0.0049 0.0066
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0049 0.0066
Leishmania major adenosine kinase, putative 0.0736 0.7497 1
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0582 0.591 0.7883
Brugia malayi MH1 domain containing protein 0.0015 0.0073 0.0097
Echinococcus multilocularis neuropeptide s receptor 0.0013 0.0049 0.0049
Echinococcus granulosus dro:myosuppressin receptor 0.0013 0.0049 0.0066
Brugia malayi hypothetical protein 0.012 0.1147 0.153
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0013 0.0046 0.0061
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0083 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0518 0.6932
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Plasmodium falciparum glutathione reductase 0.0023 0.0158 0.2112
Leishmania major adenosine kinase-like protein 0.0084 0.078 0.1041
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.1066
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0013 0.0046 0.0133
Trypanosoma brucei adenosine transporter 2 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0366 0.047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0139
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0033 0.0254 0.0737
Schistosoma mansoni hypothetical protein 0.0019 0.0112 0.015
Entamoeba histolytica hypothetical protein 0.0043 0.0364 0.0466
Echinococcus granulosus neuropeptide FF receptor 2 0.0013 0.0049 0.0066
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0033 0.0254 0.0737
Schistosoma mansoni amine GPCR 0.0013 0.0049 0.0066
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0096 0.0128
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0013 0.0046 0.0133
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0049 0.0044
Echinococcus granulosus RUN 0.001 0.0017 0.0023
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0013 0.0046 0.0046
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0376 0.0501
Echinococcus multilocularis RUN 0.001 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0019 0.0112 0.015
Plasmodium falciparum acyl-CoA synthetase 0.0022 0.0143 0.1909
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0366 0.0488
Leishmania major nucleobase transporter 0.012 0.1147 0.153
Echinococcus granulosus thioredoxin glutathione reductase 0.0023 0.0158 0.021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0053 0.0467 0.1354
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0688 0.7006 1
Brugia malayi hypothetical protein 0.0058 0.0518 0.0691
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0016 0.0083 0.0111
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0049 0.0066
Brugia malayi isocitrate dehydrogenase 0.0037 0.0293 0.0391
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0081 0.0747 0.0996
Loa Loa (eye worm) RNA binding protein 0.0064 0.058 0.0754
Trypanosoma cruzi nucleoside transporter-like, putative 0.012 0.1147 0.153
Leishmania major nucleoside transporter 1, putative 0.012 0.1147 0.153
Onchocerca volvulus 0.0013 0.0049 0.0046
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0084 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0376 0.0376
Brugia malayi AKH receptor 0.0013 0.0049 0.0066
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0139 0.0164
Brugia malayi endonuclease G, mitochondrial precursor 0.001 0.0019 0.0026
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus granulosus g protein coupled receptor 0.0013 0.0049 0.0066
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0049 0.0066
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0022 0.0139 0.0185
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0022 0.0143 0.0413
Loa Loa (eye worm) hypothetical protein 0.0084 0.078 0.1021
Brugia malayi hypothetical protein 0.0013 0.0049 0.0066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0056 0.0494 0.0659
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0084 0.012
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0366 0.0522
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0081 0.0747 0.0747
Onchocerca volvulus 0.0652 0.6633 0.9467
Schistosoma mansoni hypothetical protein 0.0058 0.0516 0.0688
Echinococcus granulosus bloom syndrome protein 0.001 0.0016 0.0022
Brugia malayi hypothetical protein 0.0148 0.144 0.192
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0016 0.0083 0.0111
Mycobacterium tuberculosis Probable dehydrogenase 0.0053 0.0467 0.1354
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0049 0.0049
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0078 0.0104
Trypanosoma brucei adenosine transporter 2, putative 0.012 0.1147 0.153
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0081 0.0747 0.0996
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0084 0.0112
Plasmodium falciparum phosphodiesterase gamma, putative 0.0081 0.0747 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0013 0.0049 0.0066
Loa Loa (eye worm) MH1 domain-containing protein 0.0012 0.0043 0.0036
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0012 0.0039 0.0112
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0049 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0125 0.0361
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0327 0.3895
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0518 0.0691
Schistosoma mansoni adenosine kinase 0.0736 0.7497 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0139 0.0198
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0536 0.0715
Onchocerca volvulus 0.0036 0.0286 0.0385
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.012 0.1147 0.153
Schistosoma mansoni equilibrative nucleoside transporter 0.012 0.1147 0.153
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0366 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0039 0.0055
Schistosoma mansoni topbp1 0.0012 0.0039 0.0052
Loa Loa (eye worm) hypothetical protein 0.0033 0.0254 0.0318
Onchocerca volvulus 0.0058 0.0516 0.0714
Brugia malayi putative neuropeptide receptor NPR1 0.0013 0.0049 0.0066
Brugia malayi hypothetical protein 0.0038 0.0305 0.0406
Brugia malayi hypothetical protein 0.0043 0.0364 0.0485
Leishmania major nucleoside transporter 1, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0016 0.0078 0.0083
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0084 0.078 0.1064
Brugia malayi Doublecortin family protein 0.001 0.0017 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0518 0.0691
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.0033 0.0254 0.0339
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma brucei adenosine transporter 2, putative 0.012 0.1147 0.153
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Onchocerca volvulus 0.0013 0.0049 0.0046
Trypanosoma cruzi adenosine kinase, putative 0.0736 0.7497 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0012 0.0039 0.0055
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0081 0.0747 0.0996
Loa Loa (eye worm) hypothetical protein 0.0012 0.0039 0.003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0001
Schistosoma mansoni hypothetical protein 0.0019 0.0112 0.015
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0366 0.0522
Toxoplasma gondii kinase, pfkB family protein 0.0736 0.7497 1
Echinococcus multilocularis mothers against decapentaplegic 2 0.0012 0.0043 0.0043
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0199 0.0266
Brugia malayi putative neuropeptide receptor 0.0013 0.0049 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.078 0.1114
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0013 0.0046 0.0061
Leishmania major tagatose-6-phosphate kinase-like protein 0.0084 0.078 0.1041
Trypanosoma cruzi nucleoside phosphatase, putative 0.0033 0.0254 0.0339
Trypanosoma cruzi adenosine kinase, putative 0.0084 0.078 0.1041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0663 0.674 0.674
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Toxoplasma gondii nucleoside transporter protein 0.012 0.1147 0.153
Toxoplasma gondii isocitrate dehydrogenase 0.0037 0.0293 0.0391
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0013 0.0046 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0033 0.0254 0.0339
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0013 0.0049 0.0066
Onchocerca volvulus Huntingtin homolog 0.0148 0.144 0.2036
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0081 0.0747 0.0996
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0013 0.0046 0.0133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0056 0.0494 0.0659
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0084 0.012
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0013 0.0049 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.0022 0.0139 0.186
Leishmania major hypothetical protein, conserved 0.0058 0.0518 0.0691
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0033 0.0254 0.0737
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Loa Loa (eye worm) transcription factor SMAD2 0.0404 0.4072 0.5422
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0049 0.0049
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0056 0.0494 0.0494
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0049 0.0066
Brugia malayi Isocitrate dehydrogenase 0.0037 0.0293 0.0391
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.1066
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0013 0.0046 0.001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0013 0.0049 0.0066
Brugia malayi G-protein coupled receptor 0.0013 0.0049 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus multilocularis sex peptide receptor 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0016 0.0084 0.009
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0049 0.0049
Schistosoma mansoni smad1 5 8 and 0.0027 0.0199 0.0266
Brugia malayi Serotonin receptor 0.0013 0.0049 0.0066
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0026 0.0186 0.0248
Echinococcus granulosus ectonucleotide 0.0014 0.0061 0.0081
Brugia malayi Pax transcription activation domain interacting protein 0.0012 0.0039 0.0052
Echinococcus granulosus smad 0.0027 0.0199 0.0266
Trypanosoma cruzi endonuclease G, putative 0.001 0.0019 0.0026
Echinococcus multilocularis serotonin receptor 0.0013 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0169
Echinococcus granulosus neuropeptide receptor 0.0013 0.0049 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0049 0.0066
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0185
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0049 0.0066
Loa Loa (eye worm) glutathione reductase 0.0023 0.0158 0.0189
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0139
Trichomonas vaginalis ribokinase, putative 0.0084 0.078 0.1114
Mycobacterium tuberculosis Ribokinase RbsK 0.0084 0.078 0.2262
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0252 0.0336
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0053 0.0467 0.1354
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0013 0.0049 0.0049
Loa Loa (eye worm) melatonin receptor type 1A 0.0013 0.0049 0.0044
Giardia lamblia hypothetical protein 0.0081 0.0747 0.1066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0037 0.0293 0.0293
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0017 0.0087 0.0117
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0049 0.0066
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.001 0.0019 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0059 0.0529 0.1533
Loa Loa (eye worm) hypothetical protein 0.0688 0.7006 0.9343
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0199 0.0199
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0049 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0013 0.0046 0.0061
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0022 0.0139 0.0185
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0366 0.047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0049 0.0066
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0013 0.0046 0.0133
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0017 0.0023
Schistosoma mansoni hypothetical protein 0.0013 0.0049 0.0066
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Schistosoma mansoni lamin 0.0033 0.0252 0.0336
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0376 0.1089
Echinococcus multilocularis bloom syndrome protein 0.001 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Echinococcus multilocularis Endonuclease G 0.001 0.0019 0.0019
Plasmodium falciparum LCCL domain-containing protein 0.001 0.0017 0.0228
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0013 0.0049 0.0066
Brugia malayi sulfakinin receptor protein 0.0013 0.0049 0.0066
Echinococcus multilocularis dro:myosuppressin receptor 0.0013 0.0049 0.0049
Schistosoma mansoni rab6-interacting 0.001 0.0017 0.0023
Schistosoma mansoni neuropeptide receptor 0.0013 0.0049 0.0066
Entamoeba histolytica fructokinase, putative 0.0084 0.078 0.1064
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0364 0.0364
Echinococcus granulosus lysosomal alpha glucosidase 0.0197 0.1942 0.2591
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0081 0.0747 0.0996
Loa Loa (eye worm) hypothetical protein 0.0015 0.0072 0.0075
Brugia malayi hypothetical protein 0.001 0.0017 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0013 0.0046 0.0061
Plasmodium falciparum nucleoside-diphosphatase, putative 0.0022 0.0139 0.186
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0376 0.0501
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0569 0.5774 0.5774
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0026 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Echinococcus multilocularis neuropeptide FF receptor 2 0.0013 0.0049 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0049 0.0066
Brugia malayi G protein-coupled receptor 0.0013 0.0049 0.0066
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0081 0.0747 0.0996
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0081 0.0747 0.0996
Echinococcus granulosus GPCR family 2 0.0019 0.0112 0.015
Echinococcus multilocularis mothers against decapentaplegic 6 0.0012 0.0043 0.0043
Onchocerca volvulus 0.0013 0.0049 0.0046
Trichomonas vaginalis antibiotic synthetase, putative 0.0013 0.0046 0.0065
Schistosoma mansoni ribokinase 0.0084 0.078 0.1041
Entamoeba histolytica kinase, PfkB family 0.0084 0.078 0.1064
Onchocerca volvulus 0.0013 0.0046 0.0041
Onchocerca volvulus 0.0084 0.078 0.1092
Echinococcus multilocularis lysosomal alpha glucosidase 0.0197 0.1942 0.1942
Onchocerca volvulus Ribokinase homolog 0.0084 0.078 0.1092
Brugia malayi MH2 domain containing protein 0.0027 0.0199 0.0266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0049 0.0049
Schistosoma mansoni amine GPCR 0.0013 0.0049 0.0066
Trichomonas vaginalis replication factor C large subunit, putative 0.0012 0.0039 0.0055
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0017 0.0087 0.0117
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0084 0.0112
Loa Loa (eye worm) thioredoxin reductase 0.0023 0.0158 0.0189
Loa Loa (eye worm) hypothetical protein 0.0013 0.0049 0.0044
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0376 0.0501
Brugia malayi Nucleoside-diphosphatase mig-23 0.0022 0.0139 0.0185
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0013 0.0049 0.0049
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0013 0.0046 0.0061
Leishmania major 4-coumarate:coa ligase-like protein 0.0033 0.0254 0.0339
Loa Loa (eye worm) hypothetical protein 0.0663 0.674 0.8988
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0084 0.078 0.078
Echinococcus multilocularis expressed protein 0.0017 0.0087 0.0087
Echinococcus granulosus orexin receptor type 2 0.0013 0.0049 0.0066
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0013 0.0049 0.0049
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0049 0.0066
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0037 0.0293 0.3927
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0081 0.0747 0.0996
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0039 0.0055
Entamoeba histolytica nucleoside transporter, putative 0.012 0.1147 0.1591
Toxoplasma gondii peptidylprolyl isomerase 0.0016 0.0083 0.0111
Echinococcus multilocularis neuropeptide receptor A26 0.0013 0.0049 0.0049
Chlamydia trachomatis DNA ligase 0.0012 0.0039 0.2718
Echinococcus multilocularis G protein coupled receptor 139 0.0013 0.0049 0.0049
Echinococcus multilocularis tar DNA binding protein 0.0064 0.058 0.058
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0366 0.0488
Onchocerca volvulus 0.0013 0.0046 0.0041
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0027 0.0198 0.0264
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0376 0.0501
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0022 0.0139 0.0198
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0366 0.0522
Mycobacterium ulcerans acyl-CoA synthetase 0.0013 0.0046 0.0133
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0013 0.0049 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0112 0.0112
Schistosoma mansoni lipoxygenase 0.001 0.0017 0.0023
Brugia malayi Nucleoside transporter family protein 0.0688 0.7006 0.9344
Loa Loa (eye worm) hypothetical protein 0.0688 0.7006 0.9343
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0081 0.0747 0.0996
Echinococcus granulosus ribokinase 0.0084 0.078 0.1041
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.012 0.1147 0.153
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.012 0.1147 0.153
Echinococcus granulosus 7TM GPCR rhodopsin 0.0013 0.0049 0.0066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0663 0.674 0.8991
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0037 0.0293 0.0391
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0081 0.0747 0.0996
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0013 0.0046 0.0133
Echinococcus granulosus lamin 0.0033 0.0252 0.0336
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0013 0.0049 0.0066
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0009 0.0004 0.0054
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0688 0.7006 1
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0012 0.0039 0.0052
Toxoplasma gondii nucleoside transporter protein 0.012 0.1147 0.153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0081 0.0747 0.1066
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0366 0.0522
Mycobacterium tuberculosis Adenosine kinase 0.0084 0.078 0.2262
Echinococcus multilocularis smad 0.0027 0.0199 0.0199
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0125 0.0361
Trypanosoma brucei unspecified product 0.012 0.1147 0.153
Toxoplasma gondii LsmAD domain-containing protein 0.0058 0.0518 0.0691
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0084 0.012

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.