Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0055 | 0.0571 | 0.098 |
Echinococcus granulosus | GPCR family 2 | 0.003 | 0.0244 | 0.0381 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.034 | 0.4319 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.0116 | 0.027 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0165 | 0.2988 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0036 | 0.0328 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.034 | 0.4319 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.0045 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.03 | 0.0489 |
Schistosoma mansoni | thyroid hormone receptor | 0.034 | 0.4319 | 0.7766 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2211 | 0.5085 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.034 | 0.4319 | 0.7766 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0047 | 0.0018 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0054 | 0.0596 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0165 | 0.1873 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0045 | 0.0441 | 0.0731 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0116 | 0.2323 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.0244 | 0.0381 |
Schistosoma mansoni | coup transcription factor | 0.034 | 0.4319 | 0.7766 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0103 | 0.12 | 0.8844 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0095 | 0.1097 | 0.249 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0034 | 0.03 | 0.048 |
Trypanosoma brucei | trypanothione reductase | 0.0045 | 0.0441 | 0.627 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0036 | 0.0321 | 0.0293 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.034 | 0.4319 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0054 | 0.0186 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0036 | 0.0321 | 0.0518 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0434 | 0.5554 | 0.9798 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0031 | 0.0003 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0054 | 0.0186 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.034 | 0.4319 | 0.7609 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.034 | 0.4319 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0443 | 0.5668 | 0.5655 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2211 | 0.5085 |
Brugia malayi | hypothetical protein | 0.018 | 0.2211 | 0.5118 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0034 | 0.03 | 0.0489 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.034 | 0.4319 | 0.7766 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.034 | 0.4319 | 0.4303 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0029 | 0.000000010465 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0197 | 0.0298 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.034 | 0.4319 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.003 | 0.0244 | 0.0216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.034 | 0.4319 | 1 |
Schistosoma mansoni | multidrug resistance protein | 0.0032 | 0.0276 | 0.0447 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0031 | 0.0258 | 0.5558 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0029 | 0.0068 |
Schistosoma mansoni | nuclear hormone receptor | 0.034 | 0.4319 | 0.7766 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.034 | 0.4319 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0054 | 0.0186 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0054 | 0.025 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0036 | 0.0321 | 0.2105 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0042 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0045 | 0.0441 | 0.627 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.018 | 0.2211 | 0.5118 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.016 | 0.1958 | 0.4496 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0114 | 0.135 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0036 | 0.0321 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.034 | 0.4319 | 0.7766 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.034 | 0.4319 | 1 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0029 | 0.000000018889 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0103 | 0.12 | 0.8844 |
Brugia malayi | Nuclear hormone receptor E75 | 0.016 | 0.1958 | 0.4533 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Trypanosoma cruzi | membrane transporter protein, putative | 0.0032 | 0.0276 | 0.3648 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.034 | 0.4319 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0054 | 0.0117 |
Schistosoma mansoni | lamin | 0.0055 | 0.0571 | 0.098 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.0025 |
Echinococcus multilocularis | musashi | 0.0055 | 0.0571 | 0.0543 |
Onchocerca volvulus | 0.016 | 0.1958 | 0.4496 | |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.034 | 0.4319 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0036 | 0.0321 | 0.6958 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.016 | 0.1958 | 0.4533 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0063 | 0.0676 | 0.1507 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.016 | 0.1958 | 0.4496 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0014 | 0.0029 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0029 | 0.000000018506 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0254 | 0.3192 | 0.3172 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.0571 | 0.1321 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0165 | 0.1873 |
Brugia malayi | nuclear receptor NHR-67 | 0.016 | 0.1958 | 0.4533 |
Echinococcus granulosus | expressed protein | 0.0032 | 0.0267 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2211 | 0.5085 |
Echinococcus granulosus | multidrug and toxin extrusion protein 2 | 0.0032 | 0.0276 | 0.0438 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.018 | 0.2211 | 0.3949 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0032 | 0.0267 | 0.0619 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0114 | 0.135 | 1 |
Brugia malayi | nuclear hormone receptor | 0.016 | 0.1958 | 0.4533 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.0116 | 0.0087 |
Leishmania major | cytochrome p450-like protein | 0.0015 | 0.0048 | 0.0008 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.034 | 0.4319 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Schistosoma mansoni | nuclear hormone receptor | 0.016 | 0.1958 | 0.3491 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0048 | 0.0043 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0103 | 0.12 | 0.8844 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0236 | 0.0481 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.0116 | 0.0203 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.016 | 0.1958 | 0.3421 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.034 | 0.4319 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.0571 | 0.096 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0165 | 0.328 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0063 | 0.0676 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0054 | 0.0117 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0585 | 0.1006 |
Onchocerca volvulus | 0.0055 | 0.0571 | 0.1262 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0443 | 0.5668 | 0.5655 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0045 | 0.0441 | 0.096 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.016 | 0.1958 | 0.3421 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.034 | 0.4319 | 0.4303 |
Brugia malayi | nuclear receptor RXR | 0.018 | 0.2211 | 0.5118 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0032 |
Echinococcus multilocularis | Multi antimicrobial extrusion protein MatE | 0.003 | 0.0239 | 0.021 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0018 |
Brugia malayi | hypothetical protein | 0.016 | 0.1958 | 0.4533 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0018 |
Schistosoma mansoni | zinc finger protein | 0.016 | 0.1958 | 0.3491 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0267 | 0.798 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.034 | 0.4319 | 0.4303 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.018 | 0.2211 | 0.5085 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.0116 | 0.2323 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0063 | 0.0676 | 0.117 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0048 | 0.011 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0165 | 0.2988 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.382 | 0.8837 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.018 | 0.2211 | 0.3869 |
Trypanosoma brucei | cytochrome P450, putative | 0.0015 | 0.0048 | 0.0008 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0267 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0062 | 0.0077 |
Loa Loa (eye worm) | steroid hormone receptor | 0.034 | 0.4319 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0031 | 0.0258 | 0.3349 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1097 | 0.249 |
Echinococcus multilocularis | expressed protein | 0.0032 | 0.0267 | 0.0239 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.034 | 0.4319 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0184 | 0.0361 |
Schistosoma mansoni | nuclear receptor | 0.016 | 0.1958 | 0.3491 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.016 | 0.1958 | 0.3421 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0236 | 0.0546 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.003 | 0.0244 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2211 | 0.5085 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.197 | 0.3514 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.016 | 0.1958 | 0.3421 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0114 | 0.135 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.034 | 0.4319 | 0.4303 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0065 | 0.0702 | 0.1626 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.003 | 0.0244 | 0.0565 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.034 | 0.4319 | 0.7609 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0244 | 0.0389 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0045 | 0.0441 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.0244 | 0.0381 |
Brugia malayi | ecdysteroid receptor | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0165 | 0.0316 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.0571 | 0.0543 |
Brugia malayi | hypothetical protein | 0.0116 | 0.1373 | 0.3179 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.018 | 0.2211 | 0.3949 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.0244 | 0.0216 |
Onchocerca volvulus | 0.034 | 0.4319 | 1 | |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0036 | 0.0321 | 0.1525 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.03 | 0.1007 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.016 | 0.1958 | 0.3421 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.016 | 0.1958 | 0.4533 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.0244 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0702 | 0.1219 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0034 | 0.03 | 0.0271 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.0046 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0036 | 0.0321 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0114 | 0.135 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0063 | 0.0676 | 0.1146 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0054 | 0.0644 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.034 | 0.4319 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.034 | 0.4319 | 0.7609 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0063 | 0.0676 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.2211 | 0.5085 |
Schistosoma mansoni | thyroid hormone receptor | 0.034 | 0.4319 | 0.7766 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0063 | 0.0676 | 1 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0032 | 0.0276 | 0.3648 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0036 | 0.0321 | 0.4363 |
Echinococcus granulosus | lamin | 0.0055 | 0.0571 | 0.096 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.007 | 0.0771 | 0.1316 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0048 | 0.0043 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.034 | 0.4319 | 0.7766 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.016 | 0.1958 | 0.4533 |
Brugia malayi | nuclear receptor NHR-88 | 0.016 | 0.1958 | 0.4533 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.018 | 0.2211 | 0.2188 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0103 | 0.12 | 0.8844 |
Schistosoma mansoni | ap endonuclease | 0.0036 | 0.0321 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0244 | 0.0501 |
Brugia malayi | steroid hormone receptor | 0.034 | 0.4319 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.003 | 0.0244 | 0.0565 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0467 |
Echinococcus granulosus | FTZ F1 alpha | 0.034 | 0.4319 | 0.7609 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0032 | 0.0276 | 0.3648 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.0117 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.034 | 0.4319 | 0.7609 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0103 | 0.12 | 0.8844 |
Trichomonas vaginalis | rotamase, putative | 0.0031 | 0.0258 | 0.7611 |
Brugia malayi | ecdysone receptor | 0.016 | 0.1958 | 0.4533 |
Brugia malayi | nuclear receptor NHR-88 | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0036 | 0.0321 | 0.7085 |
Brugia malayi | hypothetical protein | 0.016 | 0.1958 | 0.4533 |
Brugia malayi | hypothetical protein | 0.0034 | 0.03 | 0.0694 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0031 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.016 | 0.1958 | 0.1934 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.016 | 0.1958 | 0.4496 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.016 | 0.1958 | 0.3491 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0031 | 0.0258 | 0.3349 |
Brugia malayi | Thioredoxin reductase | 0.0045 | 0.0441 | 0.1021 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0048 | 0.011 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0054 | 0.0186 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.034 | 0.4319 | 0.4303 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.0267 | 0.798 |
Trypanosoma brucei | MATE efflux family protein, putative | 0.0032 | 0.0276 | 0.3648 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.016 | 0.1958 | 0.4533 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.034 | 0.4319 | 0.7766 |
Schistosoma mansoni | nuclear receptor | 0.016 | 0.1958 | 0.3491 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.0571 | 0.1321 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0109 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0053 | 0.0123 |
Plasmodium vivax | glutathione reductase, putative | 0.0045 | 0.0441 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0095 | 0.1097 | 0.2541 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0054 | 0.0117 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0045 | 0.0441 | 0.3025 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0036 | 0.0328 | 0.0299 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0165 | 0.1873 |
Plasmodium falciparum | thioredoxin reductase | 0.0045 | 0.0441 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0443 | 0.5668 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0434 | 0.5554 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0036 | 0.0321 | 0.4363 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0109 |
Echinococcus granulosus | geminin | 0.0161 | 0.197 | 0.3443 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0032 | 0.0276 | 0.3648 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0031 | 0.0258 | 0.3349 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0016 | 0.006 | 0.0056 |
Brugia malayi | tailless protein | 0.016 | 0.1958 | 0.4533 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0015 | 0.0048 | 0.0008 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.016 | 0.1958 | 0.1934 |
Echinococcus multilocularis | lamin | 0.0055 | 0.0571 | 0.0543 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0015 | 0.0047 | 0.0417 |
Echinococcus multilocularis | multidrug and toxin extrusion protein 2 | 0.0032 | 0.0276 | 0.0248 |
Toxoplasma gondii | exonuclease III APE | 0.0036 | 0.0321 | 0.71 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0197 | 0.0392 |
Echinococcus multilocularis | FTZ F1 alpha | 0.034 | 0.4319 | 0.4303 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Toxoplasma gondii | thioredoxin reductase | 0.0045 | 0.0441 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.034 | 0.4319 | 0.4303 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.0116 | 0.0155 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0054 | 0.025 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0054 | 0.0117 |
Mycobacterium tuberculosis | Probable reductase | 0.0103 | 0.12 | 0.8844 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0063 | 0.0676 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.0571 | 0.1262 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0031 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.034 | 0.4319 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.03 | 0.1007 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0244 | 0.0389 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0045 | 0.0441 | 0.0413 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0015 | 0.0048 | 0.0043 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.016 | 0.1958 | 0.1934 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Brugia malayi | conserved hypotetical protein | 0.016 | 0.1958 | 0.4533 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.0571 | 0.098 |
Brugia malayi | hypothetical protein | 0.018 | 0.2211 | 0.5118 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0031 | 0.0004 |
Onchocerca volvulus | Bile acid receptor homolog | 0.034 | 0.4319 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.034 | 0.4319 | 0.7609 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0015 | 0.0048 | 0.0008 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.034 | 0.4319 | 0.7609 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0054 | 0.0117 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0036 | 0.0321 | 0.4363 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0557 | 0.1231 |
Echinococcus multilocularis | geminin | 0.0161 | 0.197 | 0.1947 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.034 | 0.4319 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0032 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0036 | 0.0321 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0054 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0165 | 0.0382 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.4319 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0165 | 0.1873 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.007 | 0.0771 | 0.0744 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.034 | 0.4319 | 1 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0029 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Schistosoma mansoni | ap endonuclease | 0.0036 | 0.0321 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.034 | 0.4319 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0036 | 0.0321 | 0.0744 |
Brugia malayi | nuclear receptor RXR | 0.016 | 0.1958 | 0.4533 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0036 | 0.0321 | 0.4363 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0063 | 0.0676 | 0.0648 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.016 | 0.1958 | 0.1934 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.034 | 0.4319 | 0.7766 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0018 | 0.0084 | 0.0936 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0054 | 0.0117 |
Onchocerca volvulus | 0.0055 | 0.0571 | 0.1262 | |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.025 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0031 | 0.0258 | 0.3349 |
Leishmania major | trypanothione reductase | 0.0045 | 0.0441 | 0.627 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0197 | 0.0169 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.016 | 0.1958 | 0.1934 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.034 | 0.4319 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0036 | 0.0321 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0054 | 0.0596 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0244 | 0.0389 |
Schistosoma mansoni | rotamase | 0.0032 | 0.0267 | 0.0431 |
Brugia malayi | nuclear hormone receptor | 0.034 | 0.4319 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.016 | 0.1958 | 0.4533 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0054 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.0571 | 0.1262 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.034 | 0.4319 | 0.4303 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1958 | 0.4496 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0443 | 0.5668 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.016 | 0.1958 | 0.3421 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.03 | 0.1007 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.034 | 0.4319 | 0.7766 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.034 | 0.4319 | 1 |
Onchocerca volvulus | 0.016 | 0.1958 | 0.4496 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.034 | 0.4319 | 0.7766 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0029 | 0.0068 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.034 | 0.4319 | 0.4303 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0063 | 0.0676 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0063 | 0.0676 | 0.1564 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0054 | 0.0056 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.03 | 0.1007 |
Schistosoma mansoni | nuclear hormone receptor | 0.016 | 0.1958 | 0.3491 |
Schistosoma mansoni | hypothetical protein | 0.0161 | 0.197 | 0.3514 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0036 | 0.0321 | 1 |
Loa Loa (eye worm) | DR-78 | 0.016 | 0.1958 | 0.4496 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.016 | 0.1958 | 0.4496 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0036 | 0.0321 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0036 | 0.0321 | 0.0681 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.016 | 0.1958 | 0.3491 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0095 | 0.1097 | 0.2541 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0054 | 0.0644 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0244 | 0.0389 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.0571 | 0.096 |
Loa Loa (eye worm) | glutathione reductase | 0.0045 | 0.0441 | 0.096 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0702 | 0.1569 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0571 | 0.1262 |
Brugia malayi | glutathione reductase | 0.0045 | 0.0441 | 0.1021 |
Leishmania major | hypothetical protein, conserved | 0.0032 | 0.0276 | 0.3648 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0165 | 0.3315 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.016 | 0.1958 | 0.4496 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0177 | 0.0409 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0047 | 0.0018 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.034 | 0.4319 | 0.7609 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.034 | 0.4319 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0184 | 0.0361 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.018 | 0.2211 | 0.5118 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.016 | 0.1958 | 0.3491 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0177 | 0.0344 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0054 | 0.0117 |
Plasmodium falciparum | glutathione reductase | 0.0045 | 0.0441 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.