Detailed information for compound 2075943

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 417.403 | Formula: C17H18F3N3O4S
  • H donors: 1 H acceptors: 5 LogP: 2.13 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(F)(F)F.CCOCc1cncc2c1CCN(C2)C(=O)c1cscn1
  • InChi: 1S/C15H17N3O2S.C2HF3O2/c1-2-20-8-12-6-16-5-11-7-18(4-3-13(11)12)15(19)14-9-21-10-17-14;3-2(4,5)1(6)7/h5-6,9-10H,2-4,7-8H2,1H3;(H,6,7)
  • InChiKey: FDRFYLMFIRNBDX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis pikachurin 0.0111 0.103 0.103
Brugia malayi hypothetical protein 0.0385 0.4014 0.4739
Schistosoma mansoni nuclear hormone receptor 0.0212 0.2122 0.2195
Echinococcus multilocularis ecdysone induced protein 78C 0.0212 0.2122 0.2122
Echinococcus granulosus geminin 0.0596 0.6302 0.6518
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0024 0.0083 0.0098
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Loa Loa (eye worm) hypothetical protein 0.0112 0.1036 0.1223
Echinococcus granulosus survival motor neuron protein 1 0.0273 0.2788 0.2884
Brugia malayi Fli-1 protein 0.0519 0.547 0.6458
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0087 0.0363
Brugia malayi nuclear receptor RXR 0.0112 0.1036 0.1223
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Loa Loa (eye worm) hypothetical protein 0.0112 0.1036 0.1223
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0087 0.0363
Brugia malayi ShTK domain containing protein 0.0207 0.2074 0.2448
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0087 0.0992
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0212 0.2122 0.2505
Echinococcus granulosus ecdysone induced protein 78C 0.0212 0.2122 0.2195
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0744 0.0744
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0212 0.2122 0.2505
Loa Loa (eye worm) acetyltransferase 0.0167 0.1639 0.1935
Brugia malayi ecdysone receptor 0.01 0.0906 0.1069
Echinococcus multilocularis protein C ets 2 0.0025 0.0089 0.0089
Onchocerca volvulus 0.0212 0.2122 0.7552
Echinococcus multilocularis ETS transcription factor Elf 1 0.0025 0.0089 0.0089
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0024 0.0083 0.0086
Entamoeba histolytica hypothetical protein 0.0041 0.0271 0.8435
Echinococcus multilocularis dnaJ subfamily B 0.0905 0.9667 0.9667
Brugia malayi Cytochrome P450 family protein 0.0112 0.1036 0.1224
Echinococcus multilocularis sodium and chloride dependent glycine 0.0024 0.0083 0.0083
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0024 0.0083 0.0083
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0112 0.1036 0.1036
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0087 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0394 0.0407
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0111 0.103 0.1066
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0005 0.0005
Echinococcus granulosus jun protein 0.0186 0.1841 0.1905
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0024 0.0083 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0212 0.2122 0.2505
Loa Loa (eye worm) hypothetical protein 0.0111 0.103 0.1216
Brugia malayi Nuclear hormone receptor E75 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.0093 0.0832 0.0983
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0087 0.0363
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.2447 0.289
Onchocerca volvulus 0.0095 0.0851 0.3029
Echinococcus granulosus neurogenic locus notch protein 0.0111 0.103 0.1066
Onchocerca volvulus 0.0146 0.1407 0.5007
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0087 0.0363
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0212 0.2122 0.2122
Echinococcus multilocularis aryl hydrocarbon receptor 0.003 0.0144 0.0144
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0207 0.2074 0.2448
Loa Loa (eye worm) D-ets-2 protein 0.0025 0.0089 0.0106
Loa Loa (eye worm) nuclear receptor NHR-67 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0209 0.0247
Brugia malayi steroid hormone receptor 0.0212 0.2122 0.2505
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0024 0.0083 0.0086
Echinococcus granulosus protein C ets 2 0.0025 0.0089 0.0093
Loa Loa (eye worm) hypothetical protein 0.0181 0.1786 0.2108
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0207 0.2074 0.2448
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0394 0.0407
Echinococcus multilocularis ETS transcription factor Elf 5 0.0025 0.0089 0.0089
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0271 0.0281
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Schistosoma mansoni hypothetical protein 0.0905 0.9667 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0186 0.1841 0.1905
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0312 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0394 0.0465
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0312 0.0368
Echinococcus granulosus slit 2 protein 0.0111 0.103 0.1066
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0394 0.0407
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.0143 0.1373 0.1621
Brugia malayi nuclear hormone receptor 0.01 0.0906 0.1069
Loa Loa (eye worm) cytochrome P450 family protein 0.0112 0.1036 0.1224
Schistosoma mansoni hypothetical protein 0.0056 0.0425 0.044
Loa Loa (eye worm) steroid hormone receptor 0.0212 0.2122 0.2505
Echinococcus multilocularis serotonin transporter 0.0143 0.1373 0.1373
Mycobacterium ulcerans putative regulatory protein 0.0085 0.0745 1
Brugia malayi Ets-domain containing protein 0.0025 0.0089 0.0106
Echinococcus multilocularis geminin 0.0596 0.6302 0.6302
Echinococcus granulosus Nuclear hormone receptor HR96 0.01 0.0906 0.0937
Leishmania major cytochrome p450-like protein 0.0025 0.0087 0.0992
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0212 0.2122 0.2505
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0025 0.0089 0.0106
Schistosoma mansoni cpg binding protein 0.0067 0.055 0.0569
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.003 0.0144 0.0301
Schistosoma mansoni sodium-dependent amino acid transporter 0.0024 0.0083 0.0086
Schistosoma mansoni hypothetical protein 0.0145 0.14 0.1448
Onchocerca volvulus 0.0207 0.2074 0.7379
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0087 0.0992
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0374 0.3889 0.4022
Brugia malayi nuclear receptor NHR-67 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Echinococcus granulosus sodium and chloride dependent glycine 0.0024 0.0083 0.0086
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0095 0.0851 0.1005
Echinococcus multilocularis jun protein 0.0186 0.1841 0.1841
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0212 0.2122 0.2195
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0209 0.0217
Echinococcus multilocularis survival motor neuron protein 1 0.0273 0.2788 0.2788
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0087 0.0363
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.000000026163 0.000000027064
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Schistosoma mansoni laminin gamma-3 chain 0.0111 0.103 0.1066
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0209 0.0217
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0212 0.2122 0.2122
Schistosoma mansoni single-minded 0.0115 0.107 0.1107
Echinococcus multilocularis ets variant gene 4 0.0025 0.0089 0.0089
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0087 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.01 0.0906 0.0906
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.031 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0212 0.2122 0.7552
Brugia malayi nuclear receptor NHR-88 0.01 0.0906 0.1069
Brugia malayi Intermediate filament tail domain containing protein 0.0095 0.0851 0.1005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0212 0.2122 0.2505
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0025 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0212 0.2122 0.2195
Brugia malayi nuclear hormone receptor 0.0212 0.2122 0.2505
Loa Loa (eye worm) hypothetical protein 0.0095 0.0851 0.1005
Echinococcus granulosus ETS transcription factor Elf 2 0.0025 0.0089 0.0093
Onchocerca volvulus 0.0095 0.0851 0.3029
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0044 0.0053
Brugia malayi Ets-domain containing protein 0.0171 0.1681 0.1984
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.003 0.0144 0.0301
Entamoeba histolytica hypothetical protein 0.0041 0.0271 0.8435
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0352
Schistosoma mansoni elf1 0.0025 0.0089 0.0093
Brugia malayi CXXC zinc finger family protein 0.0064 0.0511 0.0603
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0062 0.0062
Entamoeba histolytica hypothetical protein 0.0041 0.0271 0.8435
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0212 0.2122 0.2195
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0025 0.0089 0.0093
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Onchocerca volvulus 0.0143 0.1373 0.4886
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0062 0.0064
Echinococcus granulosus nuclear receptor nhr 48 0.01 0.0906 0.0937
Schistosoma mansoni ets-related 0.0025 0.0089 0.0093
Brugia malayi cytoplasmic intermediate filament protein 0.0051 0.0372 0.0439
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0212 0.2122 0.2122
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Loa Loa (eye worm) hypothetical protein 0.0046 0.0317 0.0375
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0144 0.3305
Onchocerca volvulus Protein ultraspiracle homolog 0.0212 0.2122 0.7552
Echinococcus multilocularis lamin 0.0095 0.0851 0.0851
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0087 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.01 0.0906 0.0906
Brugia malayi hypothetical protein 0.0041 0.0271 0.032
Brugia malayi Uncoordinated protein 44 0.0017 0.000000026163 0.000000030889
Mycobacterium leprae Possible regulatory protein 0.003 0.0144 1
Schistosoma mansoni lamin 0.0095 0.0851 0.088
Schistosoma mansoni intermediate filament proteins 0.0095 0.0851 0.088
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0143 0.1373 0.1621
Echinococcus granulosus ETS transcription factor Elf 2 0.0025 0.0089 0.0093
Brugia malayi nuclear hormone receptor family member nhr-6 0.01 0.0906 0.1069
Echinococcus multilocularis thyroid hormone receptor alpha 0.0357 0.3702 0.3702
Loa Loa (eye worm) fli-1 protein 0.0519 0.547 0.6458
Brugia malayi DNA-binding protein D-ETS-3 0.0025 0.0089 0.0106
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.003 0.0144 0.017
Schistosoma mansoni tyrosinase precursor 0.0207 0.2074 0.2145
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0087 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0062 0.0073
Echinococcus multilocularis FTZ F1 alpha 0.0212 0.2122 0.2122
Brugia malayi PAS domain containing protein 0.0115 0.107 0.1263
Schistosoma mansoni zinc finger protein 0.01 0.0906 0.0937
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0212 0.2122 0.2505
Leishmania major cytochrome p450-like protein 0.0025 0.0087 0.0992
Schistosoma mansoni thyroid hormone receptor 0.0357 0.3702 0.383
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0112 0.1036 0.1223
Echinococcus granulosus sodium and chloride dependent glycine 0.0024 0.0083 0.0086
Leishmania major protein kinase, putative 0.003 0.0144 0.3305
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0355 0.1066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0212 0.2122 0.2122
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0047 0.0049
Brugia malayi nuclear receptor NHR-88 0.0212 0.2122 0.2505
Brugia malayi Pre-SET motif family protein 0.0036 0.0209 0.0247
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0062 0.0062
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0025 0.0089 0.0106
Onchocerca volvulus 0.01 0.0906 0.3223
Echinococcus multilocularis ETS transcription factor Elf 2 0.0025 0.0089 0.0089
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0212 0.2122 0.2505
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0053
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0186 0.1841 0.1841
Treponema pallidum sodium- and chloride- dependent transporter 0.0143 0.1373 0.5
Brugia malayi Nuclear hormone receptor E75 0.01 0.0906 0.1069
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0312 0.366
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0024 0.0083 0.0098
Brugia malayi laminin alpha chain 0.0111 0.103 0.1216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0212 0.2122 0.2505
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.01 0.0906 0.3223
Brugia malayi Cytochrome P450 family protein 0.0045 0.0312 0.0368
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0212 0.2122 0.2505
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Loa Loa (eye worm) hypothetical protein 0.003 0.0144 0.017
Trichomonas vaginalis guanylate cyclase, putative 0.003 0.0144 0.0301
Brugia malayi bZIP transcription factor family protein 0.0186 0.1841 0.2174
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0087 0.0363
Plasmodium vivax SET domain protein, putative 0.0036 0.0209 0.4649
Echinococcus granulosus dnaJ subfamily B 0.0905 0.9667 1
Echinococcus granulosus thyroid hormone receptor alpha 0.01 0.0906 0.0937
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0212 0.2122 0.2122
Onchocerca volvulus 0.0024 0.0083 0.0296
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0087 0.0992
Trichomonas vaginalis guanylate cyclase, putative 0.003 0.0144 0.0301
Brugia malayi transcription factor E74 isoform 0.0025 0.0089 0.0106
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.000000026163 0.000000027064
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0087 0.0992
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0087 0.009
Schistosoma mansoni thyroid hormone receptor 0.0357 0.3702 0.383
Onchocerca volvulus 0.003 0.0144 0.0514
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.003 0.0144 0.3305
Brugia malayi ecdysteroid receptor 0.0212 0.2122 0.2505
Schistosoma mansoni retinoic acid receptor RXR 0.0212 0.2122 0.2195
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0087 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0212 0.2122 0.2195
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0087 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0087 1
Echinococcus multilocularis nuclear receptor nhr 48 0.01 0.0906 0.0906
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0046 0.0317 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0087 1
Brugia malayi Death domain containing protein 0.0017 0.000000026163 0.000000030889
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.003 0.0144 0.3305
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0212 0.2122 0.2122
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0355 0.0367
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0087 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0005 0.0005
Onchocerca volvulus 0.0275 0.281 1
Echinococcus granulosus GA binding protein alpha chain 0.0171 0.1681 0.1738
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0087 1
Schistosoma mansoni ets-related 0.0519 0.547 0.5658
Schistosoma mansoni steroid hormone receptor ad4bp 0.0212 0.2122 0.2195
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.003 0.0144 0.0301
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0087 0.0363
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0394 0.0407
Loa Loa (eye worm) cytochrome P450 0.0025 0.0087 0.0102
Schistosoma mansoni hypothetical protein 0.0057 0.0445 0.046
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0111 0.103 0.1216
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0087 0.0363
Brugia malayi nuclear receptor RXR 0.01 0.0906 0.1069
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0207 0.2074 0.2448
Onchocerca volvulus Bile acid receptor homolog 0.0212 0.2122 0.7552
Onchocerca volvulus 0.0064 0.0511 0.1818
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0087 0.0031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.01 0.0906 0.0937
Onchocerca volvulus 0.0207 0.2074 0.7379
Brugia malayi Ets-domain containing protein 0.0171 0.1681 0.1984
Brugia malayi hypothetical protein 0.01 0.0906 0.1069
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0112 0.1036 0.1072
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0212 0.2122 0.2195
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0212 0.2122 0.2505
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0394 0.0394
Echinococcus granulosus dna polymerase eta 0.0022 0.0062 0.0064
Loa Loa (eye worm) ets-domain-containing protein 0.0025 0.0089 0.0106
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0047 0.0047
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0167 0.1639 0.1696
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0312 1
Echinococcus multilocularis ewsr:fli fusion protein type 0.0025 0.0089 0.0089
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.031 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.01 0.0906 0.0937
Loa Loa (eye worm) DR-78 0.01 0.0906 0.1069
Loa Loa (eye worm) hypothetical protein 0.0143 0.1373 0.1621
Schistosoma mansoni ets 0.0025 0.0089 0.0093
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.01 0.0906 0.0906
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0087 1
Brugia malayi Pre-SET motif family protein 0.0241 0.2447 0.289
Loa Loa (eye worm) nuclear hormone receptor 0.01 0.0906 0.1069
Schistosoma mansoni sodium/chloride dependent transporter 0.0143 0.1373 0.142
Loa Loa (eye worm) intermediate filament protein 0.0095 0.0851 0.1005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0298 0.0352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0212 0.2122 0.2505
Loa Loa (eye worm) tyrosinase 1 0.0207 0.2074 0.2448
Schistosoma mansoni survival motor neuron protein 0.0056 0.0425 0.044
Brugia malayi Cytochrome P450 family protein 0.0025 0.0087 0.0102
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0087 0.0363
Echinococcus multilocularis cpg binding protein 0.0067 0.055 0.055
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0167 0.1639 0.1639
Schistosoma mansoni gabp alpha 0.0171 0.1681 0.1738
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0209 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0212 0.2122 0.2505
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0355 1
Loa Loa (eye worm) ShTK domain-containing protein 0.0207 0.2074 0.2448
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.01 0.0906 0.3223
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0212 0.2122 0.2505
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0171 0.1681 0.1984
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Schistosoma mansoni cpg binding protein 0.0067 0.055 0.0569
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.003 0.0144 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0212 0.2122 0.2505
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0209 0.0209
Echinococcus granulosus ewsr:fli fusion protein type 0.0025 0.0089 0.0093
Schistosoma mansoni hypothetical protein 0.0025 0.0087 0.009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.1588 0.1643
Schistosoma mansoni slit 0.0111 0.103 0.1066
Brugia malayi photoreceptor-specific nuclear receptor 0.0212 0.2122 0.2505
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0144 0.0301
Brugia malayi EGF-like domain containing protein 0.0111 0.103 0.1216
Echinococcus granulosus pikachurin 0.0111 0.103 0.1066
Brugia malayi hypothetical protein 0.0112 0.1036 0.1223
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0312 0.0368
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0062 0.0073
Loa Loa (eye worm) abnormal epIthelia family member 0.0111 0.103 0.1216
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0087 0.0363
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0062 0.0064
Echinococcus granulosus Ankyrin 0.0017 0.0002 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0394 0.0465
Echinococcus granulosus FTZ F1 alpha 0.0212 0.2122 0.2195
Brugia malayi intermediate filament protein 0.0095 0.0851 0.1005
Brugia malayi cytochrome P450 0.0025 0.0087 0.0102
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0112 0.1036 0.1223
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0355 0.2457
Echinococcus granulosus ETS domain containing protein Elk 1 0.0025 0.0089 0.0093
Brugia malayi tailless protein 0.01 0.0906 0.1069
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0425 0.0502
Schistosoma mansoni jun-related protein 0.0151 0.1462 0.1513
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Brugia malayi hypoxia-induced factor 1 0.0355 0.3689 0.4355
Schistosoma mansoni sodium/chloride dependent transporter 0.0024 0.0083 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0087 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0087 0.0363
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0087 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.003 0.0144 1
Echinococcus granulosus intermediate filament protein 0.0095 0.0851 0.088
Loa Loa (eye worm) hypoxia-induced factor 1 0.0355 0.3689 0.4355
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0087 1
Schistosoma mansoni hypothetical protein 0.0151 0.1462 0.1513
Loa Loa (eye worm) ShTK domain-containing protein 0.0207 0.2074 0.2448
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0087 0.0363
Schistosoma mansoni sodium/chloride dependent transporter 0.0024 0.0083 0.0086
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0209 0.1142
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0024 0.0083 0.0098
Schistosoma mansoni coup transcription factor 0.0212 0.2122 0.2195
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0024 0.0083 0.0086
Echinococcus multilocularis dna polymerase eta 0.0022 0.0062 0.0062
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.000000026163 0.000000026163
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0087 0.0363
Trichomonas vaginalis set domain proteins, putative 0.0275 0.2808 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0106
Loa Loa (eye worm) hypothetical protein 0.0112 0.1036 0.1223
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0062 0.0064
Echinococcus granulosus aryl hydrocarbon receptor 0.003 0.0144 0.0149
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0143 0.1373 0.142
Schistosoma mansoni cell polarity protein 0.0111 0.103 0.1066
Trichomonas vaginalis adenylate cyclase, putative 0.003 0.0144 0.0301
Schistosoma mansoni RAR-like nuclear receptor 0.0212 0.2122 0.2195
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.018 0.0187
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0002 0.0002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0112 0.1036 0.1223
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0744 0.077
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.003 0.0144 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0087 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0212 0.2122 0.2195
Schistosoma mansoni hypothetical protein 0.0596 0.6302 0.6518
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.01 0.0906 0.0937
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0024 0.0083 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0087 1
Brugia malayi Protein kinase domain containing protein 0.0017 0.000000026163 0.000000030889
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0087 1
Brugia malayi follicle stimulating hormone receptor 0.0795 0.847 1
Schistosoma mansoni DNA polymerase eta 0.0022 0.0062 0.0064
Echinococcus multilocularis Ankyrin 0.0017 0.0002 0.0002
Echinococcus multilocularis ETS transcription factor Elf 2 0.0025 0.0089 0.0089
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0212 0.2122 0.2195
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0212 0.2122 0.2195
Onchocerca volvulus 0.0056 0.0425 0.1513
Echinococcus granulosus lamin dm0 0.0095 0.0851 0.088
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0087 0.0363
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0112 0.1036 0.1072
Onchocerca volvulus 0.0024 0.0083 0.0296
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0087 0.0363
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0112 0.1036 0.1072
Loa Loa (eye worm) hypothetical protein 0.0111 0.103 0.1216
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Loa Loa (eye worm) hypothetical protein 0.0143 0.1373 0.1621
Schistosoma mansoni hypothetical protein 0.0041 0.0271 0.0281
Onchocerca volvulus 0.0207 0.2074 0.7379
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0087 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0024 0.0083 0.0083
Schistosoma mansoni cytochrome P450 0.0025 0.0087 0.009
Echinococcus granulosus lamin 0.0095 0.0851 0.088
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0144 0.0301
Loa Loa (eye worm) norepinephrine transporter 0.0143 0.1373 0.1621
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0212 0.2122 0.2505
Schistosoma mansoni nuclear receptor nhr-48 0.01 0.0906 0.0937
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0212 0.2122 0.2195
Echinococcus granulosus serotonin transporter 0.0143 0.1373 0.142
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.01 0.0906 0.1069
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0212 0.2122 0.2195
Leishmania major protein kinase, putative 0.003 0.0144 0.3305
Brugia malayi hypothetical protein 0.0273 0.2788 0.3292
Brugia malayi nuclear hormone receptor family member odr-7 0.01 0.0906 0.1069
Echinococcus granulosus ETS transcription factor Elf 1 0.0025 0.0089 0.0093
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0144 0.3305
Loa Loa (eye worm) hypothetical protein 0.0207 0.2074 0.2448
Loa Loa (eye worm) hypothetical protein 0.0111 0.103 0.1216
Brugia malayi laminin-like protein K08C7.3 precursor 0.0111 0.103 0.1216
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0209 0.0217
Echinococcus granulosus single minded 2 0.0085 0.0745 0.077
Brugia malayi Nuclear hormone receptor-like 1 0.0112 0.1036 0.1223
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0212 0.2122 0.2505
Echinococcus multilocularis lamin dm0 0.0095 0.0851 0.0851
Brugia malayi acetyltransferase, GNAT family protein 0.0167 0.1639 0.1935
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0024 0.0083 0.0086
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0062 0.0073
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0795 0.847 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.1036 0.1223
Loa Loa (eye worm) hypothetical protein 0.0212 0.2122 0.2505
Brugia malayi hypothetical protein 0.01 0.0906 0.1069
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0087 0.0363
Loa Loa (eye worm) hypothetical protein 0.01 0.0906 0.1069
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0355 0.1066
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0212 0.2122 0.2195
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.003 0.0144 0.3305
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0051 0.0372 0.0439
Schistosoma mansoni cpg binding protein 0.0064 0.0511 0.0529
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.0511 0.0603
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0209 0.0209
Brugia malayi Cytochrome P450 family protein 0.0045 0.0312 0.0368
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0394 0.0394
Schistosoma mansoni tyrosinase precursor 0.0207 0.2074 0.2145
Schistosoma mansoni nuclear receptor 0.01 0.0906 0.0937
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0145 0.14 0.14
Loa Loa (eye worm) hypothetical protein 0.0025 0.0089 0.0106
Loa Loa (eye worm) hypothetical protein 0.0146 0.1411 0.1665
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.003 0.0144 0.3305
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.01 0.0906 0.0937
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0087 0.0363
Leishmania major cytochrome p450-like protein 0.0045 0.0312 1
Echinococcus multilocularis transfer RNA-Lys 0.0085 0.0745 0.0745
Brugia malayi hypothetical protein 0.0112 0.1036 0.1223
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0312 1
Echinococcus multilocularis GA binding protein alpha chain 0.0171 0.1681 0.1681
Schistosoma mansoni nuclear hormone receptor 0.01 0.0906 0.0937
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0212 0.2122 0.2195
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.01 0.0906 0.0906
Loa Loa (eye worm) hypothetical protein 0.0207 0.2074 0.2448
Schistosoma mansoni hypothetical protein 0.0025 0.0089 0.0093
Brugia malayi orphan nuclear receptor NR2E1 0.01 0.0906 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0212 0.2122 0.2505
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0144 0.0301
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0024 0.0083 0.0083
Schistosoma mansoni nuclear receptor 0.01 0.0906 0.0937
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0046 0.0317 0.0328
Echinococcus multilocularis neurogenic locus notch protein 0.0111 0.103 0.103
Loa Loa (eye worm) solute carrier family 6 member 4 0.0143 0.1373 0.1621
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0024 0.0083 0.0086
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.01 0.0906 0.0937
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0087 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0126 0.1188 1
Onchocerca volvulus 0.0085 0.0745 0.265
Schistosoma mansoni lamin 0.0095 0.0851 0.088
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0209 0.0217
Brugia malayi conserved hypotetical protein 0.01 0.0906 0.1069
Onchocerca volvulus 0.0036 0.0209 0.0745
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0087 0.0363
Loa Loa (eye worm) hypothetical protein 0.0273 0.2788 0.3292
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0024 0.0083 0.0098
Schistosoma mansoni nuclear hormone receptor 0.01 0.0906 0.0937
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0271 0.0281
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0024 0.0083 0.0086
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0212 0.2122 0.2505
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0355 0.2457
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0207 0.2074 0.2448
Brugia malayi hypothetical protein 0.0024 0.0083 0.0098
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0087 0.0363
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0394 0.0407
Loa Loa (eye worm) hypothetical protein 0.0385 0.4014 0.4739
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0087 1
Brugia malayi hypothetical protein 0.0146 0.1407 0.1661
Echinococcus granulosus cpg binding protein 0.0067 0.055 0.0569
Brugia malayi bHLH-PAS transcription factor 0.0085 0.0745 0.0879
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0212 0.2122 0.2195
Onchocerca volvulus 0.01 0.0906 0.3223
Brugia malayi Steroid receptor seven-up type 2 0.0212 0.2122 0.2505
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.003 0.0144 0.0301
Brugia malayi Common central domain of tyrosinase family protein 0.0207 0.2074 0.2448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0212 0.2122 0.2505
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.01 0.0906 0.0906
Loa Loa (eye worm) nuclear receptor nhr-7B 0.01 0.0906 0.1069
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0312 0.0368
Echinococcus multilocularis slit 2 protein 0.0111 0.103 0.103
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0087 0.0992
Loa Loa (eye worm) serotonin transporter b 0.0143 0.1373 0.1621
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0136 0.13 0.1345
Schistosoma mansoni aryl hydrocarbon receptor 0.0115 0.107 0.1107
Entamoeba histolytica hypothetical protein 0.0041 0.0271 0.8435
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0212 0.2122 0.2505
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.003 0.0144 0.3305
Schistosoma mansoni hypothetical protein 0.0596 0.6302 0.6518
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.031 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0024 0.0083 0.0098
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0062 0.0073
Echinococcus multilocularis musashi 0.0095 0.0851 0.0851
Echinococcus granulosus ETS transcription factor Elf 5 0.0025 0.0089 0.0093
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.003 0.0144 0.0301
Echinococcus multilocularis 0.0025 0.0087 0.0087
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0271 0.0271
Onchocerca volvulus 0.0207 0.2074 0.7379
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0145 0.14 0.1448
Echinococcus granulosus dna polymerase kappa 0.0022 0.0062 0.0064
Onchocerca volvulus 0.0024 0.0083 0.0296
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0005 0.0005
Brugia malayi Nuclear hormone receptor-like 1 0.0212 0.2122 0.2505
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0087 0.0363
Schistosoma mansoni hypothetical protein 0.0025 0.0089 0.0093

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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