Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.001 | 0.0162 | 0.0162 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0044 | 0.4746 | 0.4746 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0044 | 0.4746 | 0.4746 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | coup transcription factor | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0083 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.4746 | 0.4746 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | c src tyrosine kinase | 0.001 | 0.0162 | 0.0162 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0162 | 0.0162 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0083 | 1 | 1 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | tailless protein | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | nuclear hormone receptor | 0.0083 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0083 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0038 | 0.3899 | 0.3899 |
Onchocerca volvulus | 0.0083 | 1 | 1 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0083 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0039 | 0.4061 | 0.4061 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0083 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0083 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0083 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | SRC-1 | 0.0043 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | zinc finger protein | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0034 | 0.3485 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0083 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | TK protein kinase | 0.0034 | 0.3485 | 0.3485 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0034 | 0.3485 | 0.3485 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0083 | 1 | 1 |
Brugia malayi | ecdysone receptor | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0043 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.001 | 0.0162 | 0.0162 |
Schistosoma mansoni | tyrosine kinase | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0039 | 0.4061 | 0.4061 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | SRC-1 | 0.0043 | 0.4622 | 0.4622 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0083 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.001 | 0.0162 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0044 | 0.4746 | 0.4746 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0083 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | nuclear hormone receptor | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0083 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0083 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0043 | 0.4622 | 0.4622 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0083 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0039 | 0.4061 | 0.4061 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Echinococcus granulosus | tyrosine kinase | 0.0039 | 0.4061 | 0.4061 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0039 | 0.4061 | 0.4061 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0038 | 0.3899 | 0.3899 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0083 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0083 | 1 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.001 | 0.0162 | 0.0162 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0044 | 0.4746 | 0.4746 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0083 | 1 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0044 | 0.4746 | 0.4746 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.001 | 0.0162 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0083 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0034 | 0.3485 | 0.3485 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0083 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0083 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0043 | 0.4622 | 0.4622 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.4746 | 0.4746 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.001 | 0.0162 | 0.0162 |
Loa Loa (eye worm) | TK protein kinase | 0.0039 | 0.4061 | 0.4061 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0043 | 0.4622 | 0.4622 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0044 | 0.4746 | 0.4746 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Schistosoma mansoni | nuclear hormone receptor | 0.0083 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0043 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0039 | 0.4061 | 0.4061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0083 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0039 | 0.4116 | 0.4116 |
Schistosoma mansoni | tyrosine kinase | 0.001 | 0.0162 | 0.0162 |
Brugia malayi | protein-tyrosine kinase | 0.0039 | 0.4061 | 0.4061 |
Schistosoma mansoni | nuclear hormone receptor | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0083 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0083 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0039 | 0.4116 | 0.4116 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0083 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0083 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | conserved hypotetical protein | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | hypothetical protein | 0.0044 | 0.4746 | 0.4746 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0039 | 0.4116 | 0.4116 |
Echinococcus granulosus | FTZ F1 alpha | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0039 | 0.4116 | 0.4116 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0083 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0039 | 0.4116 | 0.4116 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0083 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0039 | 0.4116 | 0.4116 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.