Detailed information for compound 2076367

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 386.398 | Formula: C20H22N2O6
  • H donors: 2 H acceptors: 5 LogP: 0.21 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: n1ccc(cc1)CN1CCC(CC1)c1ccc2c(c1)OCO2.OC(=O)C(=O)O
  • InChi: 1S/C18H20N2O2.C2H2O4/c1-2-17-18(22-13-21-17)11-16(1)15-5-9-20(10-6-15)12-14-3-7-19-8-4-14;3-1(4)2(5)6/h1-4,7-8,11,15H,5-6,9-10,12-13H2;(H,3,4)(H,5,6)
  • InChiKey: XAHMADRTUWGYBJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ap endonuclease, putative 0.0096 0.098 0.1135
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0741 0.1055
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.0995 0.1416
Trichomonas vaginalis alpha-glucosidase, putative 0.0119 0.1272 0.1476
Echinococcus granulosus lamin 0.0032 0.0163 0.0163
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0046 0.034 0.034
Onchocerca volvulus 0.0243 0.2835 0.6094
Schistosoma mansoni aldo-keto reductase 0.0236 0.2747 0.2747
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0203 0.2326 0.2708
Echinococcus multilocularis muscleblind protein 1 0.0493 0.5998 0.5998
Echinococcus granulosus alkaline phosphatase 0.068 0.8368 0.8368
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0062 0.0551 0.0551
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Brugia malayi Cadherin domain containing protein 0.0019 0.0007 0.001
Mycobacterium leprae Conserved hypothetical protein 0.0167 0.1882 0.3653
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Echinococcus multilocularis intestinal type alkaline phosphatase 0.068 0.8368 0.8368
Echinococcus granulosus dna polymerase kappa 0.021 0.2414 0.2414
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0887 0.1134
Trypanosoma cruzi aldo-keto reductase 0.0236 0.2747 0.3535
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0696 0.8565 1
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0068 0.0627 0.0723
Trichomonas vaginalis alpha-glucosidase, putative 0.0119 0.1272 0.1476
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.0378 0.0538
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0145 0.0177
Entamoeba histolytica alcohol dehydrogenase, putative 0.0068 0.0627 0.0723
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0149 0.0182
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.015 0.0214
Echinococcus granulosus protein jagged 1 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Schistosoma mansoni alpha-glucosidase 0.0463 0.5616 0.5616
Trichomonas vaginalis protein disulfide isomerase, putative 0.0031 0.0152 0.0168
Loa Loa (eye worm) hypothetical protein 0.0077 0.0741 0.1055
Schistosoma mansoni microtubule-associated protein tau 0.0809 1 1
Mycobacterium ulcerans epoxide hydrolase EphA 0.034 0.4059 0.5688
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0163 0.0232
Loa Loa (eye worm) animal heme peroxidase 0.006 0.0518 0.0737
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0068 0.0627 0.2264
Trypanosoma brucei DNA polymerase eta, putative 0.0145 0.1602 0.2058
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0203 0.2326 0.8464
Brugia malayi Protein kinase domain containing protein 0.035 0.4191 0.5965
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0074 0.0704 0.0897
Schistosoma mansoni hypothetical protein 0.0033 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0033 0.0181 0.0202
Echinococcus multilocularis notch 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0049 0.0379 0.0801
Echinococcus multilocularis fibropellin Ia 0.0019 0.0007 0.0007
Leishmania major hypothetical protein, conserved 0.0077 0.0741 0.0946
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0741 0.0741
Loa Loa (eye worm) Pdia4 protein 0.0031 0.0152 0.0216
Loa Loa (eye worm) glutaminase 2 0.0574 0.7027 1
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0627 0.0723
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0995 0.2434
Trichomonas vaginalis chaperonin, putative 0.0046 0.034 0.0387
Loa Loa (eye worm) hypothetical protein 0.0493 0.5998 0.8536
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.2414 0.3106
Brugia malayi probable protein disulfide-isomerase 0.0031 0.0152 0.0216
Brugia malayi Blistered cuticle protein 3 0.006 0.0518 0.0737
Brugia malayi Animal haem peroxidase family protein 0.006 0.0518 0.0737
Echinococcus granulosus hypothetical protein 0.0236 0.2747 0.2747
Brugia malayi jmjC domain containing protein 0.029 0.3431 0.4882
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Brugia malayi jmjC domain containing protein 0.029 0.3431 0.4882
Onchocerca volvulus 0.0236 0.2747 0.5904
Echinococcus multilocularis dna polymerase eta 0.0145 0.1602 0.1602
Loa Loa (eye worm) hypothetical protein 0.0142 0.1564 0.2226
Plasmodium vivax JmjC domain containing protein 0.0077 0.0741 0.3161
Schistosoma mansoni septate junction protein 0.0019 0.0007 0.0007
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0089 0.0887 0.1134
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0149 0.0182
Schistosoma mansoni ap endonuclease 0.0096 0.098 0.098
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0325 0.037
Schistosoma mansoni protein phosphatase 2C 0.0077 0.0741 0.0741
Echinococcus granulosus neurogenic locus notch protein 0.0019 0.0007 0.0007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0077 0.0741 0.0741
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0378 0.0378
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0378 0.0477
Echinococcus granulosus synaptojanin 1 0.0019 0.0009 0.0009
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0125 0.1347 0.1728
Entamoeba histolytica phosphofructokinase, putative 0.0231 0.2687 0.3131
Trypanosoma brucei glycosyl hydrolase-like protein 0.0044 0.0325 0.0409
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0379 0.0379
Loa Loa (eye worm) hypothetical protein 0.0031 0.0156 0.0222
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0046 0.034 0.0387
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0379 0.0379
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0378 0.0432
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0019 0.0007 0.001
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0046 0.034 0.0428
Toxoplasma gondii protein disulfide isomerase 0.0031 0.0152 0.053
Leishmania major mitochondrial DNA polymerase beta 0.0631 0.7754 1
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0149 0.0166
Brugia malayi acetyltransferase, GNAT family protein 0.0109 0.1148 0.1634
Schistosoma mansoni slit 0.0019 0.0007 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0442 0.0442
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Echinococcus multilocularis protein jagged 2 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Echinococcus multilocularis dnaJ subfamily C 6 0.0146 0.1608 0.1608
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0379 0.0379
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0145 0.1602 0.228
Brugia malayi CCR4 0.0019 0.0009 0.0012
Echinococcus multilocularis phosphoglycerate kinase 1 0.0203 0.2326 0.2326
Onchocerca volvulus Peroxidase homolog 0.006 0.0518 0.1101
Entamoeba histolytica phosphofructokinase, putative 0.0231 0.2687 0.3131
Echinococcus multilocularis carboxylesterase 5A 0.0062 0.0551 0.0551
Echinococcus granulosus slit 2 protein 0.0019 0.0007 0.0007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Leishmania major DNA damage repair protein, putative 0.003 0.0145 0.0177
Brugia malayi T-complex protein 1, beta subunit 0.0046 0.034 0.0484
Mycobacterium ulcerans DNA polymerase IV 0.021 0.2414 0.3297
Echinococcus multilocularis JmjC domain containing protein 4 0.0077 0.0741 0.0741
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0236 0.2747 0.32
Brugia malayi jmjC domain containing protein 0.0077 0.0741 0.1055
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0019 0.0007 0.00000005556
Trypanosoma brucei DNA polymerase IV, putative 0.021 0.2414 0.3106
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Loa Loa (eye worm) transcription factor SMAD2 0.011 0.1151 0.1638
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Leishmania major DNA polymerase eta, putative 0.0145 0.1602 0.2058
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0236 0.2747 0.3909
Plasmodium falciparum phosphoglycerate kinase 0.0203 0.2326 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0044 0.0325 0.0409
Loa Loa (eye worm) blistered cuticle protein 3 0.006 0.0518 0.0737
Schistosoma mansoni alkaline phosphatase 0.068 0.8368 0.8368
Echinococcus multilocularis muscleblind protein 0.0493 0.5998 0.5998
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0077 0.0741 0.0946
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0046 0.034 0.143
Brugia malayi intermediate filament protein 0.0032 0.0163 0.0232
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Trypanosoma brucei phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Plasmodium falciparum T-complex protein 1 subunit beta 0.0046 0.034 0.143
Echinococcus multilocularis microtubule associated protein 2 0.0809 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Brugia malayi Pre-SET motif family protein 0.0339 0.4055 0.5771
Onchocerca volvulus Dual oxidase homolog 0.006 0.0518 0.1101
Trypanosoma cruzi aldo/keto reductase, putative 0.0236 0.2747 0.3535
Plasmodium falciparum protein disulfide isomerase 0.0031 0.0152 0.0619
Trichomonas vaginalis aldo-keto reductase, putative 0.0068 0.0627 0.0723
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Echinococcus multilocularis lysosomal alpha glucosidase 0.0537 0.6563 0.6563
Loa Loa (eye worm) oxidoreductase 0.0236 0.2747 0.3909
Echinococcus multilocularis jumonji domain containing 1A 0.0077 0.0741 0.0741
Brugia malayi exodeoxyribonuclease III family protein 0.0096 0.098 0.1394
Onchocerca volvulus 0.0236 0.2747 0.5904
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0046 0.034 0.034
Plasmodium falciparum histone acetyltransferase GCN5 0.003 0.0136 0.0551
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.021 0.2414 0.2812
Plasmodium vivax phosphoglycerate kinase, putative 0.0203 0.2326 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0119 0.1272 0.1476
Schistosoma mansoni hypothetical protein 0.0508 0.6191 0.6191
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0125 0.1347 0.3302
Loa Loa (eye worm) animal heme peroxidase 0.006 0.0518 0.0737
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0236 0.2747 0.3535
Giardia lamblia Inositol 5-phosphatase 4 0.0019 0.0009 0.0002
Mycobacterium ulcerans hypothetical protein 0.0333 0.3972 0.5561
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0325 0.037
Giardia lamblia Aldose reductase 0.0236 0.2747 0.3201
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0062 0.0553 0.0636
Loa Loa (eye worm) hypothetical protein 0.0286 0.3377 0.4805
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0149 0.0149
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Echinococcus multilocularis alkaline phosphatase 0.068 0.8368 0.8368
Schistosoma mansoni jumonji/arid domain-containing protein 0.029 0.3431 0.3431
Schistosoma mansoni alpha glucosidase 0.0119 0.1272 0.1272
Trichomonas vaginalis aldo/keto reductase, putative 0.0236 0.2747 0.32
Schistosoma mansoni serine/threonine protein kinase 0.035 0.4191 0.4191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Leishmania major phosphoglycerate kinase C, glycosomal 0.0203 0.2326 0.2992
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Echinococcus granulosus twitchin 0.0021 0.0028 0.0028
Echinococcus granulosus geminin 0.0508 0.6191 0.6191
Schistosoma mansoni synaptojanin 0.0019 0.0009 0.0009
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.034 0.4063 1
Echinococcus multilocularis aldo keto reductase 0.0236 0.2747 0.2747
Brugia malayi Pre-SET motif family protein 0.0049 0.0379 0.0539
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0236 0.2747 0.3909
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0203 0.2326 0.2992
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0741 0.1055
Onchocerca volvulus 0.006 0.0518 0.1101
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0325 0.037
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0149 0.0607
Echinococcus granulosus aldehyde reductase 0.0167 0.1882 0.1882
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.3545 0.4566
Entamoeba histolytica aldose reductase, putative 0.0236 0.2747 0.32
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Onchocerca volvulus Neurogenic locus notch homolog 0.0019 0.0007 0.00000005556
Schistosoma mansoni aldo-keto reductase 0.0236 0.2747 0.2747
Toxoplasma gondii hypothetical protein 0.0102 0.1052 0.3814
Echinococcus multilocularis neurogenic locus notch protein 0.0019 0.0007 0.0007
Echinococcus multilocularis protein jagged 1 0.0019 0.0007 0.0007
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Loa Loa (eye worm) MH2 domain-containing protein 0.011 0.1151 0.1638
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Trypanosoma brucei protein disulfide isomerase 0.0031 0.0152 0.0185
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0019 0.0009 0.0009
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.0378 0.0477
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0203 0.2326 0.2708
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0203 0.2326 0.2992
Brugia malayi transglutaminase 0.0031 0.0152 0.0216
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Leishmania major aldo-keto reductase-like protein 0.0236 0.2747 0.3535
Loa Loa (eye worm) T-complex protein 1 0.0046 0.034 0.0484
Echinococcus granulosus aldo keto reductase 0.0236 0.2747 0.2747
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0119 0.1272 0.1476
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0236 0.2747 0.3909
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0145 0.0177
Schistosoma mansoni jumonji/arid domain-containing protein 0.029 0.3431 0.3431
Trichomonas vaginalis aldo/keto reductase, putative 0.0236 0.2747 0.32
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0553 0.235
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Mycobacterium tuberculosis Probable oxidoreductase 0.0236 0.2747 0.6754
Chlamydia trachomatis phosphoglycerate kinase 0.0203 0.2326 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Leishmania major alpha glucosidase II subunit, putative 0.0119 0.1272 0.1631
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Trichomonas vaginalis phosphofructokinase, putative 0.0231 0.2687 0.3131
Loa Loa (eye worm) jmjC domain-containing protein 0.0077 0.0741 0.1055
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0097 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Echinococcus multilocularis geminin 0.0508 0.6191 0.6191
Schistosoma mansoni jumonji domain containing protein 0.029 0.3431 0.3431
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0299 0.3545 0.4566
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.068 0.8368 0.8368
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.034 0.4063 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0119 0.1272 0.4618
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0965 0.1235
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0339 0.4055 0.5771
Loa Loa (eye worm) notch protein 0.0019 0.0007 0.001
Trichomonas vaginalis ap endonuclease, putative 0.0096 0.098 0.1135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Trichomonas vaginalis protein kinase inhibitor, putative 0.0146 0.1608 0.1869
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.0378 0.0477
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0077 0.0741 0.0741
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0442 0.0442
Giardia lamblia Aldose reductase 0.0236 0.2747 0.3201
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0077 0.0741 0.0946
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.0009 0.0009
Trichomonas vaginalis aldo-keto reductase, putative 0.0068 0.0627 0.0723
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0145 0.0145
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0109 0.1148 0.1148
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0054 0.0442 0.0628
Entamoeba histolytica aldose reductase, putative 0.0236 0.2747 0.32
Loa Loa (eye worm) oxidoreductase 0.0236 0.2747 0.3909
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.035 0.4191 0.54
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.035 0.4191 0.54
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.0378 0.0477
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Brugia malayi T-complex protein 1, beta subunit 0.0046 0.034 0.0484
Trichomonas vaginalis protein disulfide isomerase, putative 0.0031 0.0152 0.0168
Loa Loa (eye worm) oxidoreductase 0.0236 0.2747 0.3909
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.05 0.0712
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0379 0.0379
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Echinococcus granulosus protein jagged 2 0.0019 0.0007 0.0007
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) 0.0028 0.0115 0.0262
Schistosoma mansoni cell polarity protein 0.0019 0.0007 0.0007
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.0378 0.0378
Brugia malayi hypothetical protein 0.006 0.0518 0.0737
Brugia malayi MAP kinase sur-1 0.0049 0.0378 0.0538
Echinococcus multilocularis neural cadherin 0.0019 0.0007 0.0007
Brugia malayi Carboxylesterase family protein 0.0062 0.0551 0.0784
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.3545 0.4566
Treponema pallidum fructose-bisphosphate aldolase 0.0696 0.8565 1
Leishmania major phosphoglycerate kinase B, cytosolic 0.0203 0.2326 0.2992
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0077 0.0741 0.268
Loa Loa (eye worm) hypothetical protein 0.0044 0.0325 0.0463
Toxoplasma gondii 6-phosphofructokinase 0.0062 0.0553 0.1994
Echinococcus multilocularis dna polymerase kappa 0.021 0.2414 0.2414
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Schistosoma mansoni protein disulfide-isomerase 0.0031 0.0152 0.0152
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.0378 0.0477
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0062 0.0553 0.0638
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0119 0.1272 0.1476
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0325 0.0463
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0887 0.1134
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0032 0.017 0.0698
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0096 0.098 0.4191
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.035 0.4191 0.5965
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.068 0.8368 0.8368
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0236 0.2747 0.3909
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.1564 0.2009
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0145 0.0177
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0325 0.037
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.7754 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0077 0.0741 0.0741
Trypanosoma cruzi DNA polymerase eta, putative 0.0078 0.0753 0.0961
Echinococcus granulosus dual specificity 0.035 0.4191 0.4191
Echinococcus granulosus peroxidasin 0.006 0.0518 0.0518
Trypanosoma cruzi hypothetical protein, conserved 0.0119 0.1272 0.1631
Loa Loa (eye worm) hypothetical protein 0.026 0.3049 0.4339
Entamoeba histolytica protein kinase, putative 0.035 0.4191 0.4888
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0096 0.098 0.4191
Onchocerca volvulus 0.0236 0.2747 0.5904
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0078 0.0753 0.2722
Onchocerca volvulus 0.0032 0.0163 0.0337
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0068 0.0627 0.2264
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0019 0.0009 0.0009
Plasmodium vivax protein disulfide isomerase, putative 0.0031 0.0152 0.0619
Giardia lamblia Protein disulfide isomerase PDI2 0.0031 0.0152 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Mycobacterium ulcerans glutaminase 0.0574 0.7027 1
Echinococcus multilocularis deoxyribonuclease 1 2 0.0019 0.0009 0.0009
Brugia malayi Animal haem peroxidase family protein 0.006 0.0518 0.0737
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0145 0.0506
Plasmodium falciparum aldo-keto reductase, putative 0.0068 0.0627 0.267
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0329 0.0469
Giardia lamblia Fructose-bisphosphate aldolase 0.0696 0.8565 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.021 0.2414 0.3106
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0696 0.8565 1
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Echinococcus multilocularis peroxidasin 0.006 0.0518 0.0518
Schistosoma mansoni nocturnin 0.0019 0.0009 0.0009
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0068 0.0627 0.0627
Echinococcus granulosus carboxylesterase 5A 0.0062 0.0551 0.0551
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.029 0.3431 0.3431
Mycobacterium ulcerans 6-phosphofructokinase 0.0231 0.2687 0.3694
Echinococcus granulosus aldo keto reductase 0.0236 0.2747 0.2747
Loa Loa (eye worm) hypothetical protein 0.0077 0.0741 0.1055
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0231 0.2687 0.6608
Onchocerca volvulus Peroxidasin homolog 0.006 0.0518 0.1101
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0096 0.098 0.1212
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0163 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Echinococcus granulosus delta-like protein 1 0.0019 0.0007 0.0007
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0019 0.0009 0.0009
Entamoeba histolytica thioredoxin, putative 0.0031 0.0152 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Schistosoma mansoni peroxidasin 0.006 0.0518 0.0518
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0046 0.034 0.034
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0553 0.235
Echinococcus multilocularis neuropeptides capa receptor 0.0196 0.2242 0.2242
Trichomonas vaginalis glutaminase, putative 0.0574 0.7027 0.8202
Loa Loa (eye worm) hypothetical protein 0.0045 0.0329 0.0469
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0019 0.0009 0.0009
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0019 0.0009 0.0012
Schistosoma mansoni alpha-glucosidase 0.0463 0.5616 0.5616
Echinococcus granulosus neutral sphingomyelinase 0.0019 0.0009 0.0009
Echinococcus granulosus phd:f box containing protein 0.0077 0.0741 0.0741
Echinococcus granulosus lamin dm0 0.0032 0.0163 0.0163
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Leishmania major protein disulfide isomerase 0.0031 0.0152 0.0185
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0379 0.0379
Mycobacterium tuberculosis Conserved protein 0.0068 0.0627 0.1526
Schistosoma mansoni hypothetical protein 0.0058 0.05 0.05
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.034 0.4063 0.5693
Brugia malayi Muscle positioning protein 4 0.0019 0.0007 0.001
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.7754 1
Plasmodium falciparum flap endonuclease 1 0.0031 0.0149 0.0607
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.1347 0.1728
Brugia malayi polk-prov protein 0.0142 0.1564 0.2226
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0054 0.0442 0.0442
Echinococcus granulosus 6 phosphofructokinase 0.0231 0.2687 0.2687
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.0378 0.0477
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0022 0.0031
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.068 0.8368 0.8368
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0149 0.0164
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Giardia lamblia hypothetical protein 0.0019 0.0009 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.003 0.0136 0.0151
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0044 0.0325 0.0686
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0145 0.0177
Echinococcus multilocularis aldo keto reductase 0.0236 0.2747 0.2747
Echinococcus multilocularis fat cadherin tumor suppressor 0.0019 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Entamoeba histolytica protein kinase, putative 0.035 0.4191 0.4888
Loa Loa (eye worm) hypothetical protein 0.0062 0.0551 0.0784
Trypanosoma brucei protein kinase, putative 0.0049 0.0378 0.0477
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Schistosoma mansoni synaptojanin 0.0019 0.0009 0.0009
Onchocerca volvulus 0.026 0.3049 0.6555
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Echinococcus granulosus neutral alpha glucosidase AB 0.0119 0.1272 0.1272
Echinococcus multilocularis protein jagged 1 0.0019 0.0007 0.0007
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0236 0.2747 0.32
Schistosoma mansoni lamin 0.0032 0.0163 0.0163
Echinococcus granulosus lysine specific demethylase 6a 0.0077 0.0741 0.0741
Echinococcus granulosus fibropellin Ia 0.0019 0.0007 0.0007
Loa Loa (eye worm) phosphofructokinase 0.0231 0.2687 0.3825
Leishmania major DNA polymerase kappa, putative 0.003 0.0145 0.0177
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.035 0.4191 0.54
Schistosoma mansoni hypothetical protein 0.0353 0.4234 0.4234
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0032 0.017 0.0597
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Leishmania major DNA polymerase kappa, putative 0.0125 0.1347 0.1728
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Echinococcus multilocularis neurogenic locus protein delta 0.0019 0.0007 0.0007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0032 0.017 0.0189
Schistosoma mansoni lamin 0.0032 0.0163 0.0163
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0049 0.0379 0.0379
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0378 0.0432
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.0378 0.0434
Echinococcus multilocularis lysine specific demethylase 5A 0.029 0.3431 0.3431
Trichomonas vaginalis DNA polymerase eta, putative 0.021 0.2414 0.2812
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Plasmodium falciparum aldehyde reductase, putative 0.0068 0.0627 0.267
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0145 0.0177
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0096 0.098 0.1135
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.0378 0.0477
Entamoeba histolytica deoxycytidyl transferase, putative 0.0097 0.0995 0.1153
Echinococcus granulosus histone acetyltransferase KAT2B 0.0032 0.017 0.017
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0145 0.0591
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0145 0.0177
Trichomonas vaginalis phosphofructokinase, putative 0.0231 0.2687 0.3131
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0231 0.2687 0.3131
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.034 0.4059 0.9991
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0009 0.0012
Echinococcus multilocularis neutral alpha glucosidase AB 0.0119 0.1272 0.1272
Loa Loa (eye worm) animal heme peroxidase 0.006 0.0518 0.0737
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0009 0.0012
Treponema pallidum exodeoxyribonuclease (exoA) 0.0096 0.098 0.1135
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Echinococcus granulosus acetylcholinesterase 0.0062 0.0551 0.0551
Plasmodium vivax aldehyde reductase, putative 0.0068 0.0627 0.267
Brugia malayi phosphofructokinase 0.0231 0.2687 0.3825
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.3377 0.3377
Brugia malayi Delta serrate ligand family protein 0.0019 0.0007 0.001
Brugia malayi Animal haem peroxidase family protein 0.006 0.0518 0.0737
Brugia malayi jmjC domain containing protein 0.0077 0.0741 0.1055
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0068 0.0627 0.0627
Toxoplasma gondii exonuclease III APE 0.0096 0.098 0.3551
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.035 0.4191 0.54
Echinococcus multilocularis lamin dm0 0.0032 0.0163 0.0163
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0054 0.0442 0.0628
Echinococcus granulosus neurogenic locus protein delta 0.0019 0.0007 0.0007
Brugia malayi Peroxidasin 0.006 0.0518 0.0737
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Echinococcus multilocularis neurogenic locus notch protein 0.0019 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.035 0.4191 0.4888
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Echinococcus granulosus dna polymerase eta 0.0145 0.1602 0.1602
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0007 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0032 0.017 0.0597
Schistosoma mansoni glutaminase 0.0574 0.7027 0.7027
Loa Loa (eye worm) 6-phosphofructokinase 0.0231 0.2687 0.3825
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.2414 0.3106
Brugia malayi Glycosyl hydrolases family 31 protein 0.0119 0.1272 0.181
Echinococcus granulosus dnaJ subfamily C 6 0.0146 0.1608 0.1608
Loa Loa (eye worm) hypothetical protein 0.0493 0.5998 0.8536
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.1564 0.2009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0537 0.6563 0.9341
Trichomonas vaginalis aldo-keto reductase, putative 0.0068 0.0627 0.0723
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0163 0.0232
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.029 0.3431 0.3431
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0089 0.0887 0.1134
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0106 0.1109 0.1109
Giardia lamblia TCP-1 chaperonin subunit beta 0.0046 0.034 0.0389
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0058 0.0498 0.1791
Echinococcus multilocularis neutral sphingomyelinase 0.0019 0.0009 0.0009
Onchocerca volvulus Chorion peroxidase homolog 0.006 0.0518 0.1101
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0046 0.034 0.0428
Brugia malayi hypothetical protein 0.0286 0.3377 0.4805
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0068 0.0627 0.0893
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.0378 0.0378
Trichomonas vaginalis sucrase-isomaltase, putative 0.0119 0.1272 0.1476
Loa Loa (eye worm) oxidoreductase 0.0236 0.2747 0.3909
Schistosoma mansoni peroxidasin 0.006 0.0518 0.0518
Schistosoma mansoni hypothetical protein 0.0508 0.6191 0.6191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0019 0.0009 0.0007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0096 0.098 0.1137
Loa Loa (eye worm) hypothetical protein 0.0049 0.0379 0.0539
Schistosoma mansoni protein disulfide-isomerase er-60 precursor (erp60) 0.0031 0.0152 0.0152
Echinococcus granulosus lysine specific demethylase 5A 0.029 0.3431 0.3431
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0145 0.0177
Schistosoma mansoni hypothetical protein 0.0146 0.1608 0.1608
Echinococcus granulosus protein disulfide isomerase 0.0031 0.0152 0.0152
Entamoeba histolytica phosphofructokinase, putative 0.0231 0.2687 0.3131
Loa Loa (eye worm) hypothetical protein 0.0031 0.015 0.0214
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0108 0.1132 0.1451
Loa Loa (eye worm) Notch2 0.0019 0.0007 0.001
Giardia lamblia DINP protein human, muc B family 0.0125 0.1347 0.1566
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0236 0.2747 0.6169
Echinococcus multilocularis musashi 0.0032 0.0163 0.0163
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0442 0.0442
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0096 0.098 0.1254
Echinococcus granulosus phosphoglycerate kinase 1 0.0203 0.2326 0.2326
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Schistosoma mansoni hypothetical protein 0.0031 0.015 0.015
Onchocerca volvulus Putative neutral sphingomyelinase 0.0019 0.0009 0.0004
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0236 0.2747 0.32
Schistosoma mansoni phosphoglycerate kinase 0.0203 0.2326 0.2326
Echinococcus multilocularis lamin 0.0032 0.0163 0.0163
Echinococcus multilocularis 6 phosphofructokinase 0.0231 0.2687 0.2687
Echinococcus granulosus traf and tnf receptor associated protein 0.0019 0.0009 0.0009
Toxoplasma gondii aldose reductase, putative 0.0236 0.2747 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0054 0.0442 0.0442
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Echinococcus granulosus neuropeptides capa receptor 0.0196 0.2242 0.2242
Brugia malayi notch-like transmembrane receptor 0.0019 0.0007 0.001
Brugia malayi Flap endonuclease-1 0.0031 0.0149 0.0213
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0068 0.0627 0.267
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0046 0.034 0.0387
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.0181 0.0181
Echinococcus granulosus muscleblind protein 0.0493 0.5998 0.5998
Mycobacterium ulcerans DNA polymerase IV 0.021 0.2414 0.3297
Echinococcus granulosus aldo keto reductase 0.0236 0.2747 0.2747
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0325 0.037
Schistosoma mansoni pol-related 0.0236 0.2747 0.2747
Brugia malayi Phosphoglycerate kinase 0.0074 0.0704 0.1002
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0231 0.2687 0.5997
Loa Loa (eye worm) oxidoreductase 0.0236 0.2747 0.3909
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0378 0.0432
Onchocerca volvulus 0.0058 0.05 0.1063
Echinococcus granulosus intestinal type alkaline phosphatase 0.068 0.8368 0.8368
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0062 0.0553 0.0636
Loa Loa (eye worm) hypothetical protein 0.0077 0.0741 0.1055
Echinococcus granulosus JmjC domain containing protein 4 0.0077 0.0741 0.0741
Entamoeba histolytica alcohol dehydrogenase, putative 0.0068 0.0627 0.0723
Leishmania major prostaglandin f synthase, putative 0.0236 0.2747 0.3535
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0231 0.2687 0.3459
Entamoeba histolytica hypothetical protein 0.0033 0.0181 0.0202
Schistosoma mansoni terminal deoxycytidyl transferase 0.0097 0.0995 0.0995
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0149 0.0213
Schistosoma mansoni flap endonuclease-1 0.0028 0.0112 0.0112
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0077 0.0741 0.268
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Echinococcus multilocularis protein disulfide isomerase 0.0031 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Loa Loa (eye worm) carboxylesterase 0.0062 0.0551 0.0784
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0231 0.2687 0.3459
Loa Loa (eye worm) hypothetical protein 0.026 0.3049 0.4339
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0236 0.2747 0.3535
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0378 0.0432
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Loa Loa (eye worm) protein disulfide isomerase 0.0031 0.0152 0.0216
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Entamoeba histolytica phosphoglycerate kinase, putative 0.0203 0.2326 0.2708
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0032 0.017 0.0189
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0096 0.098 0.098
Mycobacterium ulcerans phosphoglycerate kinase 0.0203 0.2326 0.3168
Giardia lamblia DNA damage repair protein 0.003 0.0145 0.0162
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.2414 0.3106
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.3377 0.3377
Onchocerca volvulus 0.0019 0.0009 0.0004
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0077 0.0741 0.0741
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Echinococcus granulosus neurogenic locus notch protein 0.0019 0.0007 0.0007
Schistosoma mansoni alkaline phosphatase 0.068 0.8368 0.8368
Loa Loa (eye worm) acetylcholinesterase 1 0.0062 0.0551 0.0784
Schistosoma mansoni 6-phosphofructokinase 0.0231 0.2687 0.2687
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Loa Loa (eye worm) hypothetical protein 0.0348 0.4163 0.5925
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Schistosoma mansoni phosphoglycerate kinase 0.0203 0.2326 0.2326
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Schistosoma mansoni potassium channel beta 0.0068 0.0627 0.0627
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Giardia lamblia Phosphoglycerate kinase 0.0203 0.2326 0.271
Brugia malayi Animal haem peroxidase family protein 0.006 0.0518 0.0737
Onchocerca volvulus 0.006 0.0518 0.1101
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.0378 0.1355
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0379 0.0379
Echinococcus multilocularis neurogenic locus protein delta 0.0019 0.0007 0.0007
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Brugia malayi Phosphoglycerate kinase 0.0203 0.2326 0.331
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0097 0.0995 0.1416
Schistosoma mansoni 6-phosphofructokinase 0.0231 0.2687 0.2687
Trypanosoma brucei unspecified product 0.0067 0.0613 0.078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Leishmania major ATP-dependent phosphofructokinase 0.0231 0.2687 0.3459
Echinococcus multilocularis acetylcholinesterase 0.0062 0.0551 0.0551
Trypanosoma brucei phosphoglycerate kinase 0.0203 0.2326 0.2992
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0096 0.098 0.1254
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0062 0.0553 0.0636
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0325 0.037
Trypanosoma cruzi aldo/keto reductase, putative 0.0068 0.0627 0.0799
Trypanosoma brucei phosphoglycerate kinase 0.0074 0.0704 0.0897
Onchocerca volvulus 0.006 0.0518 0.1101
Trypanosoma brucei DNA polymerase IV, putative 0.0182 0.2062 0.2651
Brugia malayi NADH-dependent xylose reductase 0.0068 0.0627 0.0893
Schistosoma mansoni phd/f-box containing protein 0.0077 0.0741 0.0741
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0325 0.037
Entamoeba histolytica acetyltransferase, GNAT family 0.003 0.0136 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.0119 0.1272 0.1631
Schistosoma mansoni survival motor neuron protein 0.0058 0.05 0.05
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Schistosoma mansoni neutral sphingomyelinase 0.0019 0.0009 0.0009
Trypanosoma brucei phosphoglycerate kinase 0.0203 0.2326 0.2992
Toxoplasma gondii t-complex protein beta subunit 0.0046 0.034 0.1216
Brugia malayi Animal haem peroxidase family protein 0.006 0.0518 0.0737
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0097 0.0995 0.0995
Trichomonas vaginalis set domain proteins, putative 0.0386 0.4648 0.5422
Schistosoma mansoni carbon catabolite repressor protein 0.0019 0.0009 0.0009
Echinococcus multilocularis phd:f box containing protein 0.0077 0.0741 0.0741
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Trichomonas vaginalis alpha-glucosidase, putative 0.0119 0.1272 0.1476
Onchocerca volvulus Peroxidase homolog 0.006 0.0518 0.1101
Loa Loa (eye worm) jmjC domain-containing protein 0.029 0.3431 0.4882
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0119 0.1272 0.181
Loa Loa (eye worm) hypothetical protein 0.0203 0.2326 0.331
Trichomonas vaginalis alpha-glucosidase, putative 0.0119 0.1272 0.1476
Echinococcus multilocularis synaptojanin 1 0.0019 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0329 0.0469
Echinococcus multilocularis lysosomal alpha glucosidase 0.0537 0.6563 0.6563
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.026 0.3049 0.3049
Onchocerca volvulus 0.0236 0.2747 0.5904
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Mycobacterium tuberculosis Conserved hypothetical protein 0.0333 0.3972 0.9776
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0145 0.0177
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.0152
Echinococcus granulosus protein jagged 1 0.0019 0.0007 0.0007
Trypanosoma cruzi bloodstream- specific protein 2 precursor 0.0031 0.0152 0.0185
Schistosoma mansoni DNA polymerase eta 0.0145 0.1602 0.1602
Loa Loa (eye worm) animal heme peroxidase 0.006 0.0518 0.0737
Brugia malayi Glycosyl hydrolases family 31 protein 0.0537 0.6563 0.9341
Onchocerca volvulus 0.0386 0.4648 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Schistosoma mansoni intermediate filament proteins 0.0032 0.0163 0.0163
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0047 0.0356 0.0356
Trypanosoma brucei glucosidase, putative 0.0119 0.1272 0.1631
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0553 0.235
Onchocerca volvulus 0.0236 0.2747 0.5904
Echinococcus multilocularis aldo keto reductase 0.0236 0.2747 0.2747
Entamoeba histolytica hypothetical protein 0.0033 0.0181 0.0202
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0007
Loa Loa (eye worm) glutaminase 0.0574 0.7027 1
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0019 0.0007 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0231 0.2687 0.3131
Brugia malayi Trypsin family protein 0.026 0.3049 0.4339
Schistosoma mansoni laminin gamma-3 chain 0.0019 0.0007 0.0007
Loa Loa (eye worm) TK/KIN16 protein kinase 0.002 0.0022 0.0031
Loa Loa (eye worm) hypothetical protein 0.0236 0.2747 0.3909
Brugia malayi protein disulphide isomerase 0.0031 0.0152 0.0216
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0068 0.0627 0.0893
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0096 0.098 0.1254
Brugia malayi Cadherin domain containing protein 0.0019 0.0007 0.001
Onchocerca volvulus 0.0068 0.0627 0.1337
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0019 0.0009 0.0012
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0068 0.0627 0.0799
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0149 0.0182
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.026 0.3049 0.3049
Plasmodium falciparum JmjC domain-containing protein, putative 0.0077 0.0741 0.3161
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Echinococcus multilocularis protein disulfide isomerase A3 0.0031 0.0152 0.0152
Onchocerca volvulus 0.0019 0.0009 0.0004
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0077 0.0741 0.0946
Schistosoma mansoni phosphatidylserine receptor 0.0077 0.0741 0.0741
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0109 0.1148 0.1148
Echinococcus granulosus flap endonuclease 1 0.0031 0.0149 0.0149
Leishmania major DNA polymerase eta, putative 0.0078 0.0753 0.0961
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0145 0.0177
Trichomonas vaginalis maltase-glucoamylase, putative 0.0119 0.1272 0.1476
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0325 0.037
Trichomonas vaginalis protein disulfide isomerase, putative 0.0031 0.0152 0.0168
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0097 0.0995 0.0995
Mycobacterium ulcerans hypothetical protein 0.0068 0.0627 0.07
Brugia malayi 6-phosphofructokinase 0.0231 0.2687 0.3825
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0203 0.2326 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0231 0.2687 0.3825
Leishmania major glycosyl hydrolase-like protein 0.0044 0.0325 0.0409
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0096 0.098 0.098
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0325 0.037
Echinococcus multilocularis voltage gated potassium channel subunit 0.0068 0.0627 0.0627
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Echinococcus multilocularis aldehyde reductase 0.0167 0.1882 0.1882
Schistosoma mansoni ap endonuclease 0.0096 0.098 0.098
Trypanosoma brucei aldo-keto reductase, putative 0.0236 0.2747 0.3535
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0046 0.034 0.034
Brugia malayi glutaminase DH11.1 0.0574 0.7027 1
Trypanosoma brucei aldo/keto reductase, putative 0.0068 0.0627 0.0799
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0019 0.0009 0.0009
Onchocerca volvulus Peroxidasin homolog 0.006 0.0518 0.1101
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0236 0.2747 0.2747
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0007 0.001
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Echinococcus granulosus lysosomal alpha glucosidase 0.0537 0.6563 0.6563
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0096 0.098 0.2395
Echinococcus multilocularis traf and tnf receptor associated protein 0.0019 0.0009 0.0009
Echinococcus multilocularis neurogenic locus notch protein 4 0.0019 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0163 0.0232
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0119 0.1272 0.1476
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0049 0.0379 0.1357
Brugia malayi EGF-like domain containing protein 0.0019 0.0007 0.001
Entamoeba histolytica aldose reductase, putative 0.0236 0.2747 0.32
Trypanosoma brucei prostaglandin f synthase 0.0236 0.2747 0.3535
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0203 0.2326 0.5715
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0096 0.098 0.1394
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0149 0.0164
Brugia malayi MH2 domain containing protein 0.011 0.1151 0.1638
Brugia malayi jmjC domain containing protein 0.0077 0.0741 0.1055
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.0378 0.0378
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0329 0.0469
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0236 0.2747 0.2747
Trichomonas vaginalis phosphofructokinase, putative 0.0231 0.2687 0.3131
Echinococcus granulosus intermediate filament protein 0.0032 0.0163 0.0163
Echinococcus multilocularis acetylcholinesterase 0.0062 0.0551 0.0551
Brugia malayi 6-phosphofructokinase 0.0231 0.2687 0.3825
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Onchocerca volvulus 0.0032 0.0163 0.0337
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0203 0.2326 0.8464
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0145 0.0591
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.068 0.8368 0.8368
Entamoeba histolytica hypothetical protein 0.0033 0.0181 0.0202
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0553 0.235
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0019 0.0009 0.0012
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Brugia malayi ImpB/MucB/SamB family protein 0.0145 0.1602 0.228
Loa Loa (eye worm) transglutaminase 0.0031 0.0152 0.0216
Brugia malayi Calcium binding EGF domain containing protein 0.0019 0.0007 0.001
Leishmania major T-complex protein 1, beta subunit, putative 0.0046 0.034 0.0428
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0044 0.0325 0.0409
Trichomonas vaginalis alpha-glucosidase, putative 0.0119 0.1272 0.1476
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0965 0.1235
Trypanosoma brucei DNA polymerase kappa, putative 0.021 0.2414 0.3106
Brugia malayi jmjC domain containing protein 0.0077 0.0741 0.1055
Schistosoma mansoni cript-related 0.0019 0.0009 0.0009
Trypanosoma brucei unspecified product 0.0067 0.0613 0.078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0054 0.0442 0.0442
Toxoplasma gondii aldo-keto reductase 0.0068 0.0627 0.2264
Plasmodium vivax SET domain protein, putative 0.0049 0.0379 0.1597
Toxoplasma gondii phosphofructokinase PFKII 0.0062 0.0553 0.1994
Echinococcus granulosus notch 0.0019 0.0007 0.0007
Brugia malayi hypothetical protein 0.0033 0.0181 0.0258
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0696 0.8565 1
Brugia malayi GCC2 and GCC3 family protein 0.0019 0.0007 0.001
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0965 0.1235
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0096 0.098 0.1254
Trichomonas vaginalis aldo-keto reductase, putative 0.0236 0.2747 0.32
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.0181 0.0181
Echinococcus multilocularis slit 2 protein 0.0019 0.0007 0.0007
Echinococcus granulosus protein jagged 2 0.0019 0.0007 0.0007
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0062 0.0553 0.1994
Trypanosoma cruzi DNA polymerase kappa, putative 0.021 0.2414 0.3106
Echinococcus granulosus jumonji domain containing 1A 0.0077 0.0741 0.0741
Schistosoma mansoni Probable protein disulfide-isomerase ER-60 precursor (ERP60) 0.0031 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0348 0.4163 0.5925
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0149 0.052
Loa Loa (eye worm) DnaJ domain-containing protein 0.0146 0.1608 0.2288
Trypanosoma brucei unspecified product 0.0182 0.2062 0.2651
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0009
Trichomonas vaginalis protein disulfide isomerase, putative 0.0031 0.0152 0.0167
Loa Loa (eye worm) hypothetical protein 0.0062 0.0551 0.0784
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0074 0.0704 0.0897
Loa Loa (eye worm) acetyltransferase 0.0109 0.1148 0.1634
Brugia malayi Muscleblind-like protein 0.0493 0.5998 0.8536
Echinococcus granulosus acetylcholinesterase 0.0062 0.0551 0.0551
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.0378 0.0378
Onchocerca volvulus 0.0236 0.2747 0.5904
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Trichomonas vaginalis aldo/keto reductase, putative 0.0236 0.2747 0.32
Brugia malayi DnaJ domain containing protein 0.0146 0.1608 0.2288
Entamoeba histolytica hypothetical protein 0.035 0.4191 0.4888
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0553 0.0636
Echinococcus multilocularis dual specificity 0.035 0.4191 0.4191
Mycobacterium ulcerans oxidoreductase 0.0236 0.2747 0.378
Brugia malayi Carboxylesterase family protein 0.0062 0.0551 0.0784
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0046 0.034 0.034
Schistosoma mansoni notch 0.0019 0.0007 0.0007
Trypanosoma cruzi DNA polymerase eta, putative 0.0145 0.1602 0.2058
Treponema pallidum phosphoglycerate kinase 0.0203 0.2326 0.2708
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0631 0.7754 1
Echinococcus granulosus neural cadherin 0.0019 0.0007 0.0007
Echinococcus granulosus neurogenic locus notch protein 4 0.0019 0.0007 0.0007
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0203 0.2326 0.4944
Echinococcus multilocularis aldo keto reductase 0.0236 0.2747 0.2747
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.006 0.0518 0.0737
Echinococcus granulosus protein disulfide isomerase A3 0.0031 0.0152 0.0152
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0019 0.0009 0.0009
Onchocerca volvulus 0.0311 0.3696 0.795

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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