Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0063 | 0.1954 | 0.2205 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0063 | 0.1954 | 0.1954 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0063 | 0.1954 | 0.2205 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0099 | 0.3981 | 0.4492 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0099 | 0.3981 | 0.4492 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0185 | 0.8863 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0099 | 0.3981 | 0.3981 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0185 | 0.8863 | 0.8863 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0099 | 0.3981 | 0.3981 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0099 | 0.3981 | 0.4492 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0063 | 0.1954 | 0.2205 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0185 | 0.8863 | 1 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0099 | 0.3981 | 0.4492 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0099 | 0.3981 | 0.4492 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0099 | 0.3981 | 0.3981 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0063 | 0.1954 | 0.1954 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Onchocerca volvulus | Notchless protein homolog | 0.0029 | 0 | 0.5 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0063 | 0.1954 | 0.2205 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Mycobacterium ulcerans | proteasome PrcB | 0.0185 | 0.8863 | 1 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0185 | 0.8863 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0185 | 0.8863 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0185 | 0.8863 | 0.8863 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0185 | 0.8863 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0029 | 0 | 0.5 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0185 | 0.8863 | 1 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0063 | 0.1954 | 0.2205 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0063 | 0.1954 | 0.1954 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0063 | 0.1954 | 0.1954 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0185 | 0.8863 | 0.8863 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.1926 | 0.1926 |
Brugia malayi | proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0063 | 0.1954 | 0.2205 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0185 | 0.8863 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0185 | 0.8863 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0099 | 0.3981 | 0.4492 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.