Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CYP4Cod1 | 0.0009 | 0.0017 | 0.0045 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0063 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0009 | 0.0017 | 0.0416 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Mycobacterium tuberculosis | Probable reductase | 0.0064 | 0.1173 | 0.6268 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0072 | 0.1324 | 0.7076 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0124 | 0.2431 | 0.6374 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.019 | 0.3815 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0025 | 0.0353 | 0.8491 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0022 | 0.027 | 0.0708 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0013 | 0.0083 | 0.0443 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0009 | 0.0017 | 0.0045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.019 | 0.3815 | 0.3815 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0583 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0193 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.3815 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.019 | 0.3815 | 1 |
Brugia malayi | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0193 | 0.0506 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.019 | 0.3815 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0101 | 0.193 | 0.5058 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.019 | 0.3815 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0018 | 0.0193 | 0.0193 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0101 | 0.193 | 0.5058 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.009 | 0.1704 | 0.4465 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.0026 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.019 | 0.3815 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.001 | 0.0024 | 0.0037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0209 | 0.5062 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0101 | 0.193 | 0.5058 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0087 | 0.1638 | 0.4294 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0012 | 0.0066 | 0.1078 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.019 | 0.3815 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.027 | 0.8742 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0064 | 0.1173 | 0.6268 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.019 | 0.3815 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0083 | 0.2011 |
Brugia malayi | nuclear receptor NHR-88 | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0012 | 0.0066 | 0.0173 |
Plasmodium vivax | SET domain protein, putative | 0.0018 | 0.0193 | 0.4358 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0012 | 0.0066 | 0.0066 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0101 | 0.193 | 0.5058 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | ecdysone receptor | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0012 | 0.0066 | 0.0173 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0028 | 0.0412 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.019 | 0.3815 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0012 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3802 | 0.9965 |
Schistosoma mansoni | rab6-interacting | 0.0012 | 0.0066 | 0.0173 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0025 | 0.0334 | 0.8104 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Brugia malayi | Pre-SET motif family protein | 0.0018 | 0.0193 | 0.0506 |
Trichomonas vaginalis | set domain proteins, putative | 0.0142 | 0.2792 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | nuclear hormone receptor | 0.019 | 0.3815 | 1 |
Brugia malayi | nuclear hormone receptor | 0.009 | 0.1704 | 0.4465 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0028 | 0.0412 | 0.2202 |
Schistosoma mansoni | nuclear hormone receptor | 0.009 | 0.1704 | 0.4465 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0064 | 0.1173 | 0.6268 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.001 | 0.0024 | 0.0063 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0009 | 0.0017 | 0.0416 |
Leishmania major | cytochrome p450-like protein | 0.0009 | 0.0017 | 0.0416 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.019 | 0.3815 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | Doublecortin family protein | 0.0012 | 0.0066 | 0.0173 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0009 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | DR-78 | 0.009 | 0.1704 | 0.4465 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0072 | 0.1324 | 0.7076 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | zinc finger protein | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | loxhd1 | 0.0012 | 0.0066 | 0.0173 |
Plasmodium vivax | glutathione reductase, putative | 0.0028 | 0.0412 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Brugia malayi | Pre-SET motif family protein | 0.0124 | 0.2431 | 0.6374 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.001 | 0.0024 | 0.0037 |
Trypanosoma brucei | trypanothione reductase | 0.0028 | 0.0412 | 1 |
Leishmania major | trypanothione reductase | 0.0028 | 0.0412 | 1 |
Brugia malayi | conserved hypotetical protein | 0.009 | 0.1704 | 0.4465 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0023 | 0.0309 | 0.7342 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0025 | 0.0353 | 0.8491 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.019 | 0.3815 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.001 | 0.0024 | 0.0128 |
Echinococcus multilocularis | FTZ F1 alpha | 0.019 | 0.3815 | 0.3815 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0037 |
Schistosoma mansoni | nuclear receptor | 0.009 | 0.1704 | 0.4465 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0098 | 0.1871 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.009 | 0.1704 | 0.4465 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0101 | 0.193 | 0.193 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0024 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0084 | 0.1587 | 0.416 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0066 | 0.0173 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.019 | 0.3815 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0013 | 0.0083 | 0.2011 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.019 | 0.3815 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0012 | 0.0066 | 0.1078 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0064 | 0.1173 | 0.6268 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0101 | 0.193 | 0.5058 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.009 | 0.1704 | 0.1704 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0016 | 0.0147 | 0.0385 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0022 | 0.027 | 0.0708 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.001 | 0.0024 | 0.0583 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.019 | 0.3815 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0028 | 0.0412 | 0.108 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.009 | 0.1704 | 0.1704 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.001 | 0.0024 | 0.0583 |
Leishmania major | DNA polymerase kappa, putative | 0.0013 | 0.0083 | 0.2011 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.3815 | 1 |
Brugia malayi | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0063 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.019 | 0.3815 | 0.3815 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0468 | 0.1226 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.001 | 0.0024 | 0.0583 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Echinococcus granulosus | dna polymerase kappa | 0.0025 | 0.0334 | 0.0875 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0087 | 0.1638 | 0.1638 |
Brugia malayi | Cytochrome P450 family protein | 0.0009 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0209 | 0.5062 |
Echinococcus multilocularis | RUN | 0.0012 | 0.0066 | 0.0066 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0033 | 0.0511 | 0.1341 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0098 | 0.1871 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.009 | 0.1704 | 0.1704 |
Brugia malayi | tailless protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0209 | 0.0547 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0072 | 0.1324 | 0.7076 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0028 | 0.0412 | 1 |
Brugia malayi | hypothetical protein | 0.0073 | 0.1347 | 0.353 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0018 | 0.0193 | 0.4358 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.019 | 0.3815 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0101 | 0.193 | 0.5058 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.019 | 0.3815 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0028 | 0.0412 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0028 | 0.0412 | 1 |
Onchocerca volvulus | 0.019 | 0.3815 | 1 | |
Loa Loa (eye worm) | acetyltransferase | 0.0087 | 0.1638 | 0.4294 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.019 | 0.3815 | 0.3815 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.019 | 0.3815 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.0147 | 0.0385 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.009 | 0.1704 | 0.1704 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0251 | 0.6094 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0066 | 0.0173 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.019 | 0.3815 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Treponema pallidum | NADH oxidase | 0.001 | 0.0024 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.019 | 0.3815 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0064 | 0.1173 | 0.6268 |
Schistosoma mansoni | polycystin 1-related | 0.0012 | 0.0066 | 0.0173 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0025 | 0.0353 | 0.119 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0025 | 0.0334 | 0.1709 |
Schistosoma mansoni | lipoxygenase | 0.0033 | 0.0511 | 0.1341 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.027 | 0.0708 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0066 | 0.0173 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0025 | 0.0353 | 0.0926 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | RUN | 0.0012 | 0.0066 | 0.0173 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.009 | 0.1704 | 0.4465 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.019 | 0.3815 | 0.3815 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0087 | 0.1638 | 0.4294 |
Loa Loa (eye worm) | doublecortin family protein | 0.0012 | 0.0066 | 0.0173 |
Brugia malayi | Nuclear hormone receptor E75 | 0.009 | 0.1704 | 0.4465 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Onchocerca volvulus | 0.0018 | 0.0193 | 0.0339 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.019 | 0.3815 | 0.3815 |
Schistosoma mansoni | lipoxygenase | 0.0012 | 0.0066 | 0.0173 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.019 | 0.3815 | 0.3815 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0023 | 0.0309 | 1 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0066 | 0.0173 |
Toxoplasma gondii | thioredoxin reductase | 0.0028 | 0.0412 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0072 | 0.1324 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.019 | 0.3815 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.019 | 0.3815 | 1 |
Brugia malayi | polk-prov protein | 0.0019 | 0.0209 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0066 | 0.0173 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0012 | 0.0066 | 0.0173 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.009 | 0.1704 | 0.4465 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.027 | 0.8742 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0009 | 0.0017 | 0.0416 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.001 | 0.0024 | 0.0583 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.009 | 0.1704 | 0.1704 |
Schistosoma mansoni | coup transcription factor | 0.019 | 0.3815 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0012 | 0.0066 | 0.0066 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0033 | 0.0511 | 0.0511 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0018 | 0.0193 | 0.0506 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.009 | 0.1704 | 0.1704 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0251 | 0.6094 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.0026 | 0.0642 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0193 | 0.0506 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Brugia malayi | steroid hormone receptor | 0.019 | 0.3815 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0025 | 0.0334 | 0.1119 |
Onchocerca volvulus | Bile acid receptor homolog | 0.019 | 0.3815 | 1 |
Brugia malayi | nuclear receptor RXR | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | hypothetical protein | 0.0101 | 0.193 | 0.5058 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3815 | 1 |
Brugia malayi | ecdysteroid receptor | 0.019 | 0.3815 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0025 | 0.0334 | 0.8104 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0193 | 0.0506 |
Echinococcus granulosus | FTZ F1 alpha | 0.019 | 0.3815 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.009 | 0.1704 | 0.4465 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.001 | 0.0024 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.027 | 0.8742 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0012 | 0.0066 | 0.0173 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.001 | 0.0024 | 0.0583 |
Brugia malayi | glutathione reductase | 0.0028 | 0.0412 | 0.108 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0193 | 0.0193 |
Onchocerca volvulus | 0.009 | 0.1704 | 0.4368 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.019 | 0.3815 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.009 | 0.1704 | 0.4368 |
Loa Loa (eye worm) | glutathione reductase | 0.0028 | 0.0412 | 0.108 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.001 | 0.0026 | 0.0642 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0025 | 0.0353 | 0.8491 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0028 | 0.0412 | 0.0412 |
Entamoeba histolytica | hypothetical protein | 0.0022 | 0.027 | 0.8742 |
Schistosoma mansoni | nuclear hormone receptor | 0.009 | 0.1704 | 0.4465 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0017 | 0.0179 | 0.047 |
Onchocerca volvulus | 0.009 | 0.1704 | 0.4368 | |
Brugia malayi | hypothetical protein | 0.0022 | 0.027 | 0.0708 |
Brugia malayi | nuclear receptor NHR-88 | 0.009 | 0.1704 | 0.4465 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.009 | 0.1704 | 0.4465 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.019 | 0.3815 | 1 |
Onchocerca volvulus | 0.0142 | 0.2792 | 0.7273 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1704 | 0.4465 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0025 | 0.0353 | 0.119 |
Brugia malayi | nuclear receptor NHR-67 | 0.009 | 0.1704 | 0.4465 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.019 | 0.3815 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.019 | 0.3815 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0193 | 0.0506 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.009 | 0.1704 | 0.4465 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.019 | 0.3815 | 0.3815 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0028 | 0.0412 | 0.108 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.019 | 0.3815 | 0.3815 |
Brugia malayi | Cytochrome P450 family protein | 0.0009 | 0.0017 | 0.0045 |
Schistosoma mansoni | nuclear receptor | 0.009 | 0.1704 | 0.4465 |
Giardia lamblia | DINP protein human, muc B family | 0.0013 | 0.0083 | 0.2065 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0025 | 0.0334 | 0.1709 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.019 | 0.3815 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.001 | 0.0024 | 0.5 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.009 | 0.1704 | 0.4368 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0101 | 0.193 | 0.5058 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.001 | 0.0024 | 0.0583 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.019 | 0.3815 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0023 | 0.0309 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.001 | 0.0024 | 0.5 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0064 | 0.1173 | 0.6268 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.009 | 0.1704 | 0.4465 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0022 | 0.027 | 0.027 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0025 | 0.0334 | 0.1119 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.001 | 0.0024 | 0.0583 |
Echinococcus multilocularis | dna polymerase kappa | 0.0025 | 0.0334 | 0.0334 |
Brugia malayi | Thioredoxin reductase | 0.0028 | 0.0412 | 0.108 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0025 | 0.0334 | 0.8104 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.