Detailed information for compound 2078376

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 373.88 | Formula: C19H24ClN5O
  • H donors: 1 H acceptors: 3 LogP: 2.15 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CC(CN1c1ccccc1)NCc1cnc(nc1)N1CCCC1.Cl
  • InChi: 1S/C19H23N5O.ClH/c25-18-10-16(14-24(18)17-6-2-1-3-7-17)20-11-15-12-21-19(22-13-15)23-8-4-5-9-23;/h1-3,6-7,12-13,16,20H,4-5,8-11,14H2;1H
  • InChiKey: CNCDTPVVHDKFRG-UHFFFAOYSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Echinococcus multilocularis serotonin receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis histone h3 methyltransferase 0.3194 1 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi ORL1-like opioid receptor 0.0046 0.0035 0.0034
Trypanosoma brucei spermidine synthase 0.0851 0.2584 0.8659
Schistosoma mansoni neuropeptide receptor 0.0046 0.0035 0.0034
Onchocerca volvulus 0.0676 0.2031 0.3968
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Echinococcus granulosus geminin 0.0153 0.0376 0.0376
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0035 0.0035
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0046 0.0035 0.0034
Toxoplasma gondii dihydropteroate synthase 0.0136 0.0322 0.0625
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0258 0.0484
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0035 0.0035
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0202 0.0531 0.1936
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi hypothetical protein 0.0291 0.0812 0.0811
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0035 0.0035
Schistosoma mansoni opsin-like receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0072 0.0118 0.0118
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Brugia malayi SET domain containing protein 0.0696 0.2096 0.2095
Echinococcus multilocularis hepatoma derived growth factor protein 0.0202 0.0531 0.0531
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0078 0.0138 0.0137
Trypanosoma cruzi spermidine synthase, putative 0.0851 0.2584 1
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0035 0.0035
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0035 0.0034
Schistosoma mansoni hypothetical protein 0.0046 0.0037 0.0036
Echinococcus granulosus cpg binding protein 0.0641 0.1921 0.1921
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0035 0.0035
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0976 0.2979 0.2979
Schistosoma mansoni hypothetical protein 0.0046 0.0035 0.0034
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0035 0.0035
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0147 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis arginine glutamic acid dipeptide (RE) repeats 0.0078 0.0138 0.0138
Onchocerca volvulus 0.0202 0.0531 0.0985
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0107 0.0231 0.0659
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Mycobacterium ulcerans spermidine synthase 0.0671 0.2017 1
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0035 0.0034
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni suppressor of variegation 4-20-related 0.0147 0.0356 0.0355
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0046 0.0037 0.0037
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0035 0.0034
Onchocerca volvulus 0.0638 0.1912 0.3731
Onchocerca volvulus 0.1634 0.5065 1
Brugia malayi polybromodomain protein 0.0078 0.0138 0.0137
Schistosoma mansoni opsin-like receptor 0.0046 0.0035 0.0034
Brugia malayi putative neuropeptide receptor 0.0046 0.0035 0.0034
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0061 0.0085 0.0105
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0035 0.0035
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0094 0.0187 0.0353
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Toxoplasma gondii phosphorylase family protein 0.0062 0.0087 0.011
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0469 0.1377 0.4552
Loa Loa (eye worm) hypothetical protein 0.007 0.0112 0.0112
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0035 0.0035
Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 0.0136 0.0322 0.0526
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0035 0.0034
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0062 0.0087 0.0197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Giardia lamblia S-adenosylmethionine synthetase 0.0091 0.0178 1
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0087 0.01
Loa Loa (eye worm) PWWP domain-containing protein 0.0202 0.0531 0.0531
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0035 0.0034
Schistosoma mansoni myosin xvIII 0.0046 0.0035 0.0034
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0035 0.0034
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0976 0.2979 0.6421
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0046 0.0037 0.0037
Echinococcus granulosus methyltransferase protein 5 0.0046 0.0037 0.0037
Brugia malayi G-protein coupled receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0035 0.0035
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0035 0.0034
Echinococcus granulosus SET and MYND domain containing protein 3 0.0072 0.0118 0.0118
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0976 0.2979 0.2978
Echinococcus granulosus hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi hypothetical protein 0.0202 0.0531 0.053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0246 0.0669 0.0669
Echinococcus granulosus somatostatin receptor 0.0046 0.0035 0.0035
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0061 0.0085 0.0085
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0085 0.0095
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0086 0.0164 0.0164
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0202 0.0531 0.1936
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0078 0.0138 0.0138
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0035 0.0035
Trypanosoma cruzi spermidine synthase, putative 0.0851 0.2584 1
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Loa Loa (eye worm) hypothetical protein 0.0188 0.0485 0.0485
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0051 0.0053 0.0051
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0229 0.0615 0.183
Brugia malayi MTAP 0.0335 0.0952 0.0951
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0035 0.0035
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0062 0.0087 0.0104
Echinococcus granulosus neuropeptide receptor A26 0.0046 0.0035 0.0035
Schistosoma mansoni purine nucleoside phosphorylase 0.0062 0.0087 0.0086
Schistosoma mansoni hypothetical protein 0.0202 0.0531 0.053
Echinococcus granulosus jumonji domain containing protein 0.0037 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0202 0.0531 0.0531
Brugia malayi G protein-coupled receptor 0.0046 0.0035 0.0034
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0062 0.0087 0.0197
Leishmania major spermidine synthase 0.0851 0.2584 0.8659
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0246 0.0669 0.0668
Echinococcus granulosus metastasis associated protein MTA1 0.0078 0.0138 0.0138
Echinococcus granulosus spermidine synthase 0.0851 0.2584 0.2584
Echinococcus granulosus PWWP domain containing protein 2A 0.0202 0.0531 0.0531
Trypanosoma cruzi spermidine synthase, putative 0.0851 0.2584 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0035 0.0035
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0405 0.1174 0.3865
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni amine GPCR 0.0046 0.0035 0.0034
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0035 0.0035
Schistosoma mansoni phd finger protein 0.0202 0.0531 0.053
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0469 0.1377 0.4552
Loa Loa (eye worm) hypothetical protein 0.0107 0.0231 0.0231
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0035 0.0034
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0553
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0107 0.0231 0.0761
Loa Loa (eye worm) SET domain-containing protein 0.0147 0.0356 0.0356
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0676 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0081 0.0147 0.0147
Schistosoma mansoni enhancer of zeste ezh 0.0696 0.2096 0.2095
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0291 0.0812 0.0812
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0405 0.1174 0.4464
Loa Loa (eye worm) hypothetical protein 0.0078 0.0138 0.0138
Schistosoma mansoni polybromo-1 0.0078 0.0138 0.0137
Echinococcus multilocularis protein arginine methyltransferase 0.0061 0.0085 0.0085
Brugia malayi hypothetical protein 0.0107 0.0231 0.023
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0035 0.0035
Brugia malayi hypothetical protein 0.0202 0.0531 0.053
Schistosoma mansoni protein arginine n-methyltransferase 0.0165 0.0413 0.0411
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0185 0.0477 0.0476
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0335 0.0952 0.3589
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1737 0.5389 0.5389
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0085 0.0095
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0078 0.0138 0.0137
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0035 0.0035
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0035 0.0035
Onchocerca volvulus 0.0291 0.0812 0.1544
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0202 0.0531 0.1936
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0035 0.0035
Schistosoma mansoni opsin-like receptor 0.0046 0.0035 0.0034
Schistosoma mansoni cpg binding protein 0.0638 0.1912 0.1911
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Loa Loa (eye worm) CXXC zinc finger family protein 0.0638 0.1912 0.1912
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0006 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0035 0.0035
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0035 0.0034
Echinococcus granulosus metastasis associated protein 1 mta1 0.0078 0.0138 0.0138
Trypanosoma brucei uridine phosphorylase 0.0062 0.0087 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Trypanosoma brucei transcription elongation factor s-II, putative 0.0202 0.0531 0.1677
Echinococcus granulosus serotonin receptor 0.0046 0.0035 0.0035
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0035 0.0035
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0062 0.0087 0.017
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0185 0.0477 0.0966
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) methionine adenosyltransferase 0.0091 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0035 0.0035
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0976 0.2979 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Trichomonas vaginalis origin recognition complex subunit, putative 0.0078 0.0138 0.02
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni microtubule-associated protein tau 0.0705 0.2124 0.2123
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0035 0.0035
Toxoplasma gondii phosphorylase family protein 0.0062 0.0087 0.011
Loa Loa (eye worm) hypothetical protein 0.0246 0.0669 0.0669
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0035 0.0034
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni methylthioadenosine phosphorylase 0.0062 0.0087 0.0086
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1471 0.4547 0.4547
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis PWWP domain containing protein 2A 0.0202 0.0531 0.0531
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus granulosus protein arginine methyltransferase 0.0061 0.0085 0.0085
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0291 0.0812 0.0812
Trichomonas vaginalis CDC6, putative 0.0078 0.0138 0.02
Leishmania major hypothetical protein, conserved 0.0202 0.0531 0.1677
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0035 0.0034
Onchocerca volvulus 0.0202 0.0531 0.0985
Brugia malayi Dopamine receptor protein 2 0.0046 0.0035 0.0034
Echinococcus granulosus arginine glutamic acid dipeptide RE repeats 0.0078 0.0138 0.0138
Brugia malayi neuropeptide F receptor 0.0046 0.0035 0.0034
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0061 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0062 0.0087 0.01
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0165 0.0413 0.0413
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0085 0.0084
Echinococcus granulosus PWWP domain containing protein 2A 0.0202 0.0531 0.0531
Echinococcus granulosus polybromo 1 0.0078 0.0138 0.0138
Echinococcus multilocularis disco interacting protein 2 0.0676 0.2031 0.2031
Echinococcus multilocularis metastasis associated protein MTA1 0.0078 0.0138 0.0138
Echinococcus granulosus peregrin 0.0228 0.0614 0.0614
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0185 0.0477 0.0477
Wolbachia endosymbiont of Brugia malayi S-adenosylmethionine synthetase 0.0091 0.0178 0.5
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0035 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Schistosoma mansoni cpg binding protein 0.0641 0.1921 0.192
Brugia malayi Serotonin receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis spermidine synthase 0.0851 0.2584 0.2584
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0035 0.0035
Brugia malayi larval opioid receptor 0.0046 0.0035 0.0034
Schistosoma mansoni hypothetical protein 0.0046 0.0035 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0246 0.0669 0.0668
Leishmania major S-adenosylmethionine synthetase 0.0091 0.0178 0.0479
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Plasmodium falciparum spermidine synthase 0.0851 0.2584 0.5546
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0035 0.0035
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0147 0.0356 0.0356
Brugia malayi CXXC zinc finger family protein 0.0638 0.1912 0.1911
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Schistosoma mansoni hepatoma derived growth factor 0.0202 0.0531 0.053
Schistosoma mansoni neuropeptide receptor 0.0046 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.1737 0.5389 0.5389
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0165 0.0413 0.0824
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0696 0.2096 0.2096
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Leishmania major S-adenosylmethionine synthetase 0.0091 0.0178 0.0479
Leishmania major nucleoside phosphorylase-like protein 0.0062 0.0087 0.017
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0035 0.0035
Schistosoma mansoni cpg binding protein 0.0641 0.1921 0.192
Brugia malayi Serotonin receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis uridine phosphorylase 1 0.0062 0.0087 0.0087
Brugia malayi F/Y-rich N-terminus family protein 0.0045 0.0032 0.0031
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0035 0.0035
Schistosoma mansoni uridine phosphorylase 0.0062 0.0087 0.0086
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0087 0.01
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0035 0.0034
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Echinococcus multilocularis neuropeptide s receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis bromo adjacent y domain containing 1 0.0078 0.0138 0.0138
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0085 0.0084
Leishmania major methylthioadenosine phosphorylase, putative 0.0335 0.0952 0.3108
Treponema pallidum S-adenosylmethionine synthetase 0.0091 0.0178 1
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Leishmania major hypothetical protein, conserved 0.0405 0.1174 0.3865
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0696 0.2096 0.2096
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0469 0.1377 0.5258
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0335 0.0952 0.3589
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Echinococcus granulosus allatostatin A receptor 0.0046 0.0035 0.0035
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Schistosoma mansoni hepatoma derived growth factor 0.0202 0.0531 0.053
Brugia malayi Dopamine receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0054 0.0063 0.0063
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0035 0.0034
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Echinococcus granulosus neuropeptide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0469 0.1377 0.1376
Leishmania major hypothetical protein, conserved 0.0405 0.1174 0.3865
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0035 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0373 0.1071 0.107
Plasmodium vivax SET domain protein, putative 0.0185 0.0477 0.1355
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Schistosoma mansoni amine GPCR 0.0046 0.0035 0.0034
Echinococcus multilocularis serotonin receptor 0.0046 0.0035 0.0035
Brugia malayi jmjC domain containing protein 0.0086 0.0164 0.0163
Echinococcus granulosus methylthioadenosine phosphorylase 0.0335 0.0952 0.0952
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0035 0.0035
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0062 0.0087 0.0008
Schistosoma mansoni S-adenosylmethionine synthetase 0.0091 0.0178 0.0177
Schistosoma mansoni hypothetical protein 0.0153 0.0376 0.0375
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0062 0.0087 0.017
Echinococcus granulosus disco interacting protein 2 0.0676 0.2031 0.2031
Loa Loa (eye worm) hypothetical protein 0.0194 0.0506 0.0506
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0062 0.0087 0.017
Brugia malayi NNMT/PNMT/TEMT family protein 0.1737 0.5389 0.5389
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0035 0.0035
Mycobacterium ulcerans S-adenosylmethionine synthetase 0.0091 0.0178 0.0471
Brugia malayi Protein arginine N-methyltransferase 0.0046 0.0037 0.0036
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0335 0.0952 0.0952
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0035 0.0035
Schistosoma mansoni histamine h1 receptor 0.0046 0.0035 0.0034
Brugia malayi PWWP domain containing protein 0.0202 0.0531 0.053
Loa Loa (eye worm) hypothetical protein 0.0291 0.0812 0.0812
Echinococcus granulosus g protein coupled receptor 0.0046 0.0035 0.0035
Leishmania major modification methylase-like protein 0.0976 0.2979 1
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0006 0.0006
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Echinococcus multilocularis S adenosylmethionine synthase type 1 0.0091 0.0178 0.0178
Schistosoma mansoni biogenic amine receptor 0.0046 0.0035 0.0034
Echinococcus granulosus uridine phosphorylase 1 0.0062 0.0087 0.0087
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0676 0.2031 0.203
Brugia malayi Pre-SET motif family protein 0.022 0.0586 0.0585
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Trypanosoma cruzi spermidine synthase, putative 0.0851 0.2584 1
Toxoplasma gondii S-adenosyl methionine synthetase 0.0091 0.0178 0.0309
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0405 0.1174 0.4464
Brugia malayi SET domain containing protein 0.0103 0.0216 0.0215
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0405 0.1174 0.4464
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) Carm1-pending protein 0.0165 0.0413 0.0413
Schistosoma mansoni SET domain protein 0.0227 0.0608 0.0607
Schistosoma mansoni biogenic amine receptor 0.0046 0.0035 0.0034
Plasmodium vivax spermidine synthase, putative 0.0851 0.2584 0.8636
Echinococcus granulosus neuropeptide receptor 0.0046 0.0035 0.0035
Onchocerca volvulus 0.0119 0.0266 0.0459
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0086 0.0164 0.0164
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0035 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0035 0.0034
Loa Loa (eye worm) spermidine synthase 0.0851 0.2584 0.2584
Echinococcus multilocularis purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Brugia malayi G-protein coupled receptor 0.0046 0.0035 0.0034
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0107 0.0231 0.0659
Trypanosoma cruzi hypothetical protein, conserved 0.0202 0.0531 0.1936
Echinococcus multilocularis neuropeptide receptor A26 0.0046 0.0035 0.0035
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0469 0.1377 0.5258
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0229 0.0615 0.1175
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0035 0.0035
Echinococcus granulosus bromo adjacent y domain containing 1 0.0078 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi Spermidine synthase 0.0851 0.2584 0.2584
Echinococcus granulosus sex peptide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0202 0.0531 0.053
Echinococcus granulosus histone lysine methyltransferase setb 0.0246 0.0669 0.0669
Schistosoma mansoni uridine phosphorylase 0.0062 0.0087 0.0086
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0035 0.0035
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0078 0.0138 0.0138
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi S-adenosylmethionine synthetase 0.0091 0.0178 0.0177
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0224 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.3194 1 1
Schistosoma mansoni bromo adjacent homology domain containing 0.0078 0.0138 0.0137
Leishmania major arginine N-methyltransferase-like protein 0.0061 0.0085 0.0162
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0006 0.0006
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0062 0.0087 0.01
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0061 0.0085 0.0084
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0094 0.0187 0.0226
Schistosoma mansoni purine nucleoside phosphorylase 0.0062 0.0087 0.0086
Schistosoma mansoni hypothetical protein 0.0078 0.0138 0.0137
Echinococcus multilocularis PWWP domain containing protein 2A 0.0202 0.0531 0.0531
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0553
Brugia malayi Pre-SET motif family protein 0.1471 0.4547 0.4547
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0671 0.2017 1
Mycobacterium tuberculosis 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) ( 0.0457 0.1336 0.6473
Loa Loa (eye worm) hypothetical protein 0.1737 0.5389 0.5389
Echinococcus granulosus S adenosylmethionine synthase type 1 0.0091 0.0178 0.0178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0035 0.0034
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0035 0.0035
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0976 0.2979 0.6459
Brugia malayi Carm1-pending protein 0.0165 0.0413 0.0411
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0035 0.0035
Toxoplasma gondii hypothetical protein 0.1485 0.4592 1
Schistosoma mansoni hypothetical protein 0.0153 0.0376 0.0375
Leishmania major histone-lysine N-methyltransferase, putative 0.0405 0.1174 0.3865
Echinococcus multilocularis geminin 0.0153 0.0376 0.0376
Echinococcus granulosus orexin receptor type 2 0.0046 0.0035 0.0035
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0335 0.0952 0.0952
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0035 0.0034
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0062 0.0087 0.017
Mycobacterium leprae Probable2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase FolK (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokin 0.0593 0.1767 1
Trypanosoma brucei histone-lysine n-methyltransferase 0.0405 0.1174 0.3865
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0405 0.1174 0.3865
Echinococcus granulosus hepatoma derived growth factor protein 0.0202 0.0531 0.0531
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Schistosoma mansoni biogenic amine receptor 0.0046 0.0035 0.0034
Schistosoma mansoni methylthioadenosine phosphorylase 0.0335 0.0952 0.0951
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0035 0.0035
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Schistosoma mansoni histone J3 methyltransferase 0.3194 1 1
Plasmodium vivax hydroxymethylpterin pyrophosphokinase-dihydropteroate synthetase, putative 0.0136 0.0322 0.082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Chlamydia trachomatis bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase 0.0136 0.0322 1
Echinococcus granulosus g protein coupled receptor 0.0046 0.0035 0.0035
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0035 0.0034
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0107 0.0231 0.0761
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0062 0.0087 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Trichomonas vaginalis set domain proteins, putative 0.1634 0.5065 1
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0469 0.1377 0.1377
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0046 0.0035 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0062 0.0087 0.017
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Echinococcus multilocularis peregrin 0.0228 0.0614 0.0614
Schistosoma mansoni methylthioadenosine phosphorylase 0.0335 0.0952 0.0951
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.0035 0.0035
Entamoeba histolytica hypothetical protein 0.0062 0.0087 0.017
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0035 0.0035
Brugia malayi hypothetical protein 0.0291 0.0812 0.0811
Toxoplasma gondii hypothetical protein 0.0202 0.0531 0.1083
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0294 0.0293
Echinococcus multilocularis cpg binding protein 0.0641 0.1921 0.1921
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0062 0.0087 0.017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Toxoplasma gondii hypothetical protein 0.0405 0.1174 0.2497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Entamoeba histolytica hypothetical protein 0.0202 0.0531 0.1677
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus granulosus histone h3 methyltransferase 0.3194 1 1
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0335 0.0952 0.4479
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Schistosoma mansoni adenoreceptor 0.0046 0.0035 0.0034
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi GnHR receptor homolog 0.0046 0.0035 0.0034
Schistosoma mansoni neuropeptide receptor 0.0046 0.0035 0.0034
Schistosoma mansoni amine GPCR 0.0046 0.0035 0.0034
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0035 0.0035
Brugia malayi follicle stimulating hormone receptor 0.0046 0.0035 0.0034
Brugia malayi AKH receptor 0.0046 0.0035 0.0034
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0976 0.2979 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0405 0.1174 0.4464
Brugia malayi Disco-interacting protein 2 homolog 0.0676 0.2031 0.203
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0469 0.1377 0.4552
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis jumonji domain containing protein 0.0037 0.0007 0.0007
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0035 0.0035
Brugia malayi sulfakinin receptor protein 0.0046 0.0035 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0035 0.0035
Echinococcus multilocularis polybromo 1 0.0078 0.0138 0.0138
Echinococcus granulosus purine nucleoside phosphorylase 0.0062 0.0087 0.0087
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0035 0.0034
Schistosoma mansoni amine GPCR 0.0046 0.0035 0.0034
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Leishmania major S-adenosylmethionine decarboxylase 0.0469 0.1377 0.4552
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0035 0.0035
Brugia malayi uridine phosphorylase family protein 0.0062 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Toxoplasma gondii DNA methyltransferase 2, putative 0.0976 0.2979 0.6459
Schistosoma mansoni hypothetical protein 0.0202 0.0531 0.053
Plasmodium falciparum S-adenosylmethionine synthetase 0.0091 0.0178 0.0207
Brugia malayi Dopamine receptor protein 1 0.0046 0.0035 0.0034
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0035 0.0035
Toxoplasma gondii Purine nucleoside phosphorylase 0.0062 0.0087 0.011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0469 0.1377 0.1377
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0335 0.0952 0.3108
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0035 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0035 0.0035
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0078 0.0138 0.0137
Mycobacterium ulcerans 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase 0.0593 0.1767 0.8708
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0035 0.0034
Plasmodium vivax S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0322
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0224 0.0599 0.0599
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0198 0.0517 0.0517
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.0479
Echinococcus granulosus protein arginine N methyltransferase 8 0.0061 0.0085 0.0085
Echinococcus granulosus fmrfamide receptor 0.0046 0.0035 0.0035
Schistosoma mansoni amine GPCR 0.0046 0.0035 0.0034
Entamoeba histolytica hypothetical protein 0.0107 0.0231 0.0659
Echinococcus multilocularis microtubule associated protein 2 0.0705 0.2124 0.2124
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0078 0.0138 0.0137
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0062 0.0087 0.0197
Echinococcus granulosus microtubule associated protein 2 0.0705 0.2124 0.2124
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Echinococcus granulosus g protein coupled receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Brugia malayi SET domain containing protein 0.0209 0.0553 0.0552
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0035 0.0034
Echinococcus multilocularis sex peptide receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0035 0.0035
Plasmodium falciparum purine nucleoside phosphorylase 0.0062 0.0087 0.0005
Brugia malayi Melatonin receptor type 1A 0.0046 0.0035 0.0034
Echinococcus multilocularis somatostatin receptor 0.0046 0.0035 0.0035
Brugia malayi ELM2 domain containing protein 0.0078 0.0138 0.0137
Onchocerca volvulus 0.0373 0.1071 0.2059
Loa Loa (eye worm) hypothetical protein 0.0078 0.0138 0.0138
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0035 0.0035
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0035 0.0035
Brugia malayi neuropeptide F receptor 0.0046 0.0035 0.0034
Schistosoma mansoni jumonji domain containing protein 0.0069 0.0108 0.0107
Loa Loa (eye worm) uridine phosphorylase 0.0062 0.0087 0.0087
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0035 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0202 0.0531 0.1936
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0035 0.0035
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0091 0.0178 0.028
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0976 0.2979 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0035 0.0034
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.1485 0.4592 1
Echinococcus granulosus protein arginine N methyltransferase 7 0.0046 0.0037 0.0037
Brugia malayi hypothetical protein 0.0046 0.0035 0.0034
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0273 0.0755 0.3461
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0035 0.0035
Echinococcus granulosus neuropeptide s receptor 0.0046 0.0035 0.0035
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0469 0.1377 0.1377
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0165 0.0413 0.0413
Brugia malayi GATA zinc finger family protein 0.0078 0.0138 0.0137
Loa Loa (eye worm) SET domain-containing protein 0.0696 0.2096 0.2096
Schistosoma mansoni neuropeptide receptor 0.0046 0.0035 0.0034
Brugia malayi RE15519p 0.0046 0.0035 0.0034
Echinococcus granulosus DNA methyltransferase 2, putative 0.0976 0.2979 0.2979
Brugia malayi SET domain containing protein 0.0147 0.0356 0.0355

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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