Detailed information for compound 2078383

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 342.263 | Formula: C16H21Cl2N3O
  • H donors: 1 H acceptors: 1 LogP: 3.66 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1n(C)nc(c1CNC1CCc2c1cccc2Cl)C.Cl
  • InChi: 1S/C16H20ClN3O.ClH/c1-10-13(16(21-3)20(2)19-10)9-18-15-8-7-11-12(15)5-4-6-14(11)17;/h4-6,15,18H,7-9H2,1-3H3;1H
  • InChiKey: UTEYGPOVDQQCMJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.3504
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0195 0.0877 0.121
Echinococcus multilocularis polybromo 1 0.0068 0.0195 0.0269
Echinococcus granulosus histone lysine N methyltransferase Ez 0.024 0.1118 0.1543
Mycobacterium ulcerans S-adenosylmethionine synthetase 0.0107 0.0408 0.5
Echinococcus multilocularis bromo adjacent y domain containing 1 0.0068 0.0195 0.0269
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1727 0.9097 1
Echinococcus granulosus polybromo 1 0.0068 0.0195 0.0269
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.022 0.1012 0.1396
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0937 0.4859 0.6704
Echinococcus granulosus histone h3 methyltransferase 0.1383 0.7248 1
Echinococcus granulosus peregrin 0.0236 0.1098 0.1514
Echinococcus multilocularis PWWP domain containing protein 2A 0.0205 0.0931 0.1284
Schistosoma mansoni protein arginine n-methyltransferase 0.0195 0.0877 0.121
Brugia malayi polybromodomain protein 0.0068 0.0195 0.0215
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0937 0.4859 0.6704
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.038 0.0524
Loa Loa (eye worm) hypothetical protein 0.0053 0.0119 0.0131
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Echinococcus granulosus SET and MYND domain containing protein 3 0.0085 0.0288 0.0397
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0937 0.4859 1
Echinococcus granulosus geminin 0.0181 0.0803 0.1108
Toxoplasma gondii histone lysine methyltransferase SET1 0.008 0.0263 0.039
Loa Loa (eye worm) hypothetical protein 0.0068 0.0195 0.0215
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0065 0.009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0255 0.1201 0.1657
Echinococcus granulosus hepatoma derived growth factor protein 0.0205 0.0931 0.1284
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0068 0.0195 0.0269
Echinococcus granulosus arginine glutamic acid dipeptide RE repeats 0.0068 0.0195 0.0269
Echinococcus granulosus histone lysine methyltransferase setb 0.0255 0.1201 0.1657
Schistosoma mansoni suppressor of variegation 4-20-related 0.0163 0.0708 0.0976
Leishmania major S-adenosylmethionine synthetase 0.0107 0.0408 0.0596
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0009 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0178 0.0195
Schistosoma mansoni enhancer of zeste ezh 0.024 0.1118 0.1543
Trichomonas vaginalis origin recognition complex subunit, putative 0.0068 0.0195 0.007
Toxoplasma gondii DNA methyltransferase 2, putative 0.0937 0.4859 0.7223
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.4302 0.5936
Schistosoma mansoni hypothetical protein 0.0055 0.0126 0.0174
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.038 0.0524
Toxoplasma gondii hypothetical protein 0.0205 0.0931 0.1383
Toxoplasma gondii hypothetical protein 0.1286 0.6728 1
Brugia malayi SET domain containing protein 0.0085 0.0287 0.0316
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0205 0.0931 1
Echinococcus granulosus bromo adjacent y domain containing 1 0.0068 0.0195 0.0269
Loa Loa (eye worm) CXXC zinc finger family protein 0.0544 0.2749 0.3022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0209 0.0954 0.1316
Schistosoma mansoni S-adenosylmethionine synthetase 0.0107 0.0408 0.0563
Brugia malayi NNMT/PNMT/TEMT family protein 0.1067 0.5558 0.611
Echinococcus multilocularis protein arginine methyltransferase 0.0072 0.0221 0.0305
Toxoplasma gondii S-adenosyl methionine synthetase 0.0107 0.0408 0.0606
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0046 0.0063
Leishmania major hypothetical protein, conserved 0.0176 0.0774 0.137
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0937 0.4859 1
Onchocerca volvulus 0.014 0.0584 0.0584
Brugia malayi PWWP domain containing protein 0.0205 0.0931 0.1023
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0055 0.0126 0.0174
Brugia malayi Carm1-pending protein 0.0195 0.0877 0.0964
Echinococcus granulosus metastasis associated protein 1 mta1 0.0068 0.0195 0.0269
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.1286 0.6728 1
Loa Loa (eye worm) hypothetical protein 0.1383 0.7248 0.7968
Loa Loa (eye worm) hypothetical protein 0.0255 0.1201 0.132
Schistosoma mansoni hypothetical protein 0.006 0.0156 0.0216
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0313 0.1511 0.2085
Echinococcus granulosus PWWP domain containing protein 2A 0.0205 0.0931 0.1284
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0184 0.0817 0.1215
Echinococcus granulosus histone lysine n methyltransferase setb1 0.0041 0.0051 0.007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0255 0.1201 0.1657
Schistosoma mansoni hypothetical protein 0.0205 0.0931 0.1284
Loa Loa (eye worm) hypothetical protein 0.0068 0.0195 0.0215
Plasmodium vivax SET domain protein, putative 0.0184 0.0817 0.1682
Echinococcus multilocularis PWWP domain containing protein 2A 0.0205 0.0931 0.1284
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0205 0.0931 1
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Echinococcus granulosus protein arginine N methyltransferase 8 0.0072 0.0221 0.0305
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0085 0.0288 0.0397
Brugia malayi SET domain containing protein 0.024 0.1118 0.1229
Echinococcus multilocularis arginine glutamic acid dipeptide (RE) repeats 0.0068 0.0195 0.0269
Plasmodium vivax S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0839
Brugia malayi S-adenosylmethionine synthetase 0.0107 0.0408 0.0448
Entamoeba histolytica hypothetical protein 0.0127 0.0514 0.082
Echinococcus granulosus disco interacting protein 2 0.0585 0.2972 0.41
Loa Loa (eye worm) Carm1-pending protein 0.0195 0.0877 0.0964
Echinococcus multilocularis histone h3 methyltransferase 0.1383 0.7248 1
Brugia malayi hypothetical protein 0.0205 0.0931 0.1023
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0089 0.0308 0.2269
Leishmania major hypothetical protein, conserved 0.0205 0.0931 0.17
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0011 0.0015
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0046 0.0063
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0176 0.0774 0.8059
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Schistosoma mansoni hepatoma derived growth factor 0.0205 0.0931 0.1284
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0068 0.0195 0.0269
Schistosoma mansoni hypothetical protein 0.0181 0.0803 0.1108
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Echinococcus granulosus metastasis associated protein MTA1 0.0068 0.0195 0.0269
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0176 0.0774 0.8059
Loa Loa (eye worm) hypothetical protein 0.0129 0.0527 0.0579
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0089 0.0308 0.0386
Schistosoma mansoni SET domain protein 0.0222 0.1022 0.1411
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0089 0.0308 0.0339
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0072 0.0221 0.0305
Loa Loa (eye worm) SET domain-containing protein 0.024 0.1118 0.1229
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.0022 0.0024
Echinococcus multilocularis geminin 0.0181 0.0803 0.1108
Loa Loa (eye worm) PWWP domain-containing protein 0.0205 0.0931 0.1023
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Echinococcus granulosus cpg binding protein 0.0546 0.276 0.3807
Brugia malayi GATA zinc finger family protein 0.0068 0.0195 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0184 0.0817 0.1128
Trypanosoma brucei transcription elongation factor s-II, putative 0.0205 0.0931 0.17
Schistosoma mansoni cpg binding protein 0.0544 0.2749 0.3793
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0127 0.0514 0.082
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0046 0.0063
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Schistosoma mansoni polybromo-1 0.0068 0.0195 0.0269
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.024 0.1118 0.1543
Echinococcus multilocularis peregrin 0.0236 0.1098 0.1514
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0072 0.0221 0.0305
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.1383 0.7248 0.7968
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0068 0.0195 0.0269
Loa Loa (eye worm) hypothetical protein 0.0205 0.0931 0.1023
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0931 1
Brugia malayi jmjC domain containing protein 0.004 0.0046 0.005
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0072 0.0221 0.0455
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0072 0.0221 0.0305
Loa Loa (eye worm) hypothetical protein 0.1067 0.5558 0.611
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Brugia malayi Disco-interacting protein 2 homolog 0.0585 0.2972 0.3267
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1067 0.5558 0.611
Plasmodium falciparum S-adenosylmethionine synthetase 0.0107 0.0408 0.0606
Toxoplasma gondii hypothetical protein 0.0176 0.0774 0.1151
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0055 0.0126 0.0187
Echinococcus granulosus protein arginine methyltransferase 0.0072 0.0221 0.0305
Schistosoma mansoni hypothetical protein 0.0205 0.0931 0.1284
Echinococcus granulosus microtubule associated protein 2 0.0833 0.4302 0.5936
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0072 0.0221 0.0097
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0068 0.0195 0.0269
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0937 0.4859 0.7223
Echinococcus multilocularis S adenosylmethionine synthase type 1 0.0107 0.0408 0.0563
Onchocerca volvulus 0.0585 0.2972 0.2972
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0072 0.0221 0.0329
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Leishmania major arginine N-methyltransferase-like protein 0.0072 0.0221 0.0201
Brugia malayi jmjC domain containing protein 0.0102 0.038 0.0417
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0184 0.0817 0.1128
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0195 0.0877 0.121
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0176 0.0774 0.8059
Brugia malayi Bromodomain containing protein 0.0033 0.0009 0.001
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0127 0.0514 0.082
Loa Loa (eye worm) hypothetical protein 0.0134 0.0553 0.0608
Brugia malayi hypothetical protein 0.0127 0.0514 0.0565
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0585 0.2972 0.41
Onchocerca volvulus 0.0205 0.0931 0.0931
Entamoeba histolytica hypothetical protein 0.0205 0.0931 0.17
Echinococcus multilocularis hepatoma derived growth factor protein 0.0205 0.0931 0.1284
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0127 0.0514 0.4823
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.022 0.1012 0.1396
Schistosoma mansoni hypothetical protein 0.0068 0.0195 0.0269
Brugia malayi hypothetical protein 0.0205 0.0931 0.1023
Trichomonas vaginalis CDC6, putative 0.0068 0.0195 0.007
Leishmania major hypothetical protein, conserved 0.0176 0.0774 0.137
Brugia malayi ELM2 domain containing protein 0.0068 0.0195 0.0215
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0055 0.0126 0.0138
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0937 0.4859 1
Schistosoma mansoni histone J3 methyltransferase 0.1383 0.7248 1
Schistosoma mansoni cpg binding protein 0.0546 0.276 0.3807
Loa Loa (eye worm) hypothetical protein 0.1067 0.5558 0.611
Echinococcus multilocularis disco interacting protein 2 0.0585 0.2972 0.41
Onchocerca volvulus 0.0313 0.1511 0.1511
Loa Loa (eye worm) hypothetical protein 0.0127 0.0514 0.0565
Leishmania major S-adenosylmethionine synthetase 0.0107 0.0408 0.0596
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0072 0.0221 0.0097
Schistosoma mansoni hepatoma derived growth factor 0.0205 0.0931 0.1284
Leishmania major S-adenosylmethionine decarboxylase 0.0089 0.0308 0.0386
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Brugia malayi Pre-SET motif family protein 0.1727 0.9097 1
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0205 0.0931 1
Echinococcus granulosus S adenosylmethionine synthase type 1 0.0107 0.0408 0.0563
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0089 0.0308 0.0386
Echinococcus multilocularis histone lysine n methyltransferase setb1 0.0041 0.0051 0.007
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.01 0.0369 0.0549
Trypanosoma brucei histone-lysine n-methyltransferase 0.0176 0.0774 0.137
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0195 0.0877 0.1303
Brugia malayi Pre-SET motif family protein 0.0224 0.1035 0.1138
Leishmania major modification methylase-like protein 0.0937 0.4859 1
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.01 0.0369 0.076
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0089 0.0308 0.0386
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0089 0.0308 0.0426
Wolbachia endosymbiont of Brugia malayi S-adenosylmethionine synthetase 0.0107 0.0408 0.5
Onchocerca volvulus 0.0544 0.2749 0.2749
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0072 0.0221 0.0329
Echinococcus multilocularis cpg binding protein 0.0546 0.276 0.3807
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0089 0.0308 0.0339
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0163 0.0708 0.0976
Loa Loa (eye worm) hypothetical protein 0.0083 0.0276 0.0304
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.4302 0.5936
Schistosoma mansoni hypothetical protein 0.0181 0.0803 0.1108
Echinococcus granulosus protein arginine N methyltransferase 7 0.0055 0.0126 0.0174
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0089 0.0308 0.0426
Echinococcus granulosus PWWP domain containing protein 2A 0.0205 0.0931 0.1284
Schistosoma mansoni bromo adjacent homology domain containing 0.0068 0.0195 0.0269
Onchocerca volvulus 0.0205 0.0931 0.0931
Trypanosoma cruzi hypothetical protein, conserved 0.0205 0.0931 1
Schistosoma mansoni hypothetical protein 0.0205 0.0931 0.1284
Echinococcus multilocularis metastasis associated protein MTA1 0.0068 0.0195 0.0269
Schistosoma mansoni phd finger protein 0.0205 0.0931 0.1284
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Treponema pallidum S-adenosylmethionine synthetase 0.0107 0.0408 0.5
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0065 0.009
Loa Loa (eye worm) methionine adenosyltransferase 0.0107 0.0408 0.0448
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0163 0.0708 0.0976
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0089 0.0308 0.2269
Trypanosoma brucei S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0072 0.0221 0.0097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0009 0.0013
Echinococcus granulosus methyltransferase protein 5 0.0055 0.0126 0.0174
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0176 0.0774 0.8059
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0043 0.0065 0.0133
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0068 0.0195 0.0269
Echinococcus granulosus DNA methyltransferase 2, putative 0.0937 0.4859 0.6704
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0072 0.0221 0.0305
Giardia lamblia S-adenosylmethionine synthetase 0.0107 0.0408 1
Loa Loa (eye worm) hypothetical protein 0.0585 0.2972 0.3267
Trypanosoma cruzi S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.3504
Brugia malayi CXXC zinc finger family protein 0.0544 0.2749 0.3022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0088 0.0305 0.0421
Brugia malayi SET domain containing protein 0.0145 0.0608 0.0669
Loa Loa (eye worm) hypothetical protein 0.0068 0.0195 0.0215
Leishmania major histone-lysine N-methyltransferase, putative 0.0176 0.0774 0.137
Schistosoma mansoni cpg binding protein 0.0546 0.276 0.3807
Loa Loa (eye worm) hypothetical protein 0.0041 0.0051 0.0056
Brugia malayi Protein arginine N-methyltransferase 0.0055 0.0126 0.0138
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0937 0.4859 0.7223
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0043 0.0065 0.0096
Loa Loa (eye worm) SET domain-containing protein 0.0163 0.0708 0.0778
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0127 0.0514 0.4823
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0035 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0206 0.0226
Trichomonas vaginalis set domain proteins, putative 0.1896 1 1
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0176 0.0774 0.137
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0046 0.005
Trichomonas vaginalis S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0286
Entamoeba histolytica S-adenosylmethionine synthetase, putative 0.0107 0.0408 0.0596
Brugia malayi SET domain containing protein 0.0163 0.0708 0.0778
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0255 0.1201 0.1657
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0176 0.0774 0.137
Toxoplasma gondii bicoid-interacting protein BIN3 0.0055 0.0126 0.0187
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0267 0.0369

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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