Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | farnesyltransferase, CAAX box, alpha | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0193 | 0.5868 | 1 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0193 | 0.5868 | 0.558 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Animal haem peroxidase family protein | 0.0177 | 0.4988 | 0.8314 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0135 | 0.2543 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0143 | 0.3017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Animal haem peroxidase family protein | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5868 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0265 | 1 | 1 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0193 | 0.5868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Onchocerca volvulus | Peroxidase homolog | 0.0177 | 0.4988 | 1 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0135 | 0.2543 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0265 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 0.4988 | 1 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0193 | 0.5868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Onchocerca volvulus | Peroxidase homolog | 0.0177 | 0.4988 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.0135 | 0.2543 | 0.2023 |
Echinococcus granulosus | peroxidasin | 0.0177 | 0.4988 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0177 | 0.4988 | 0.8314 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.5868 | 1 |
Brugia malayi | Peroxidasin | 0.0177 | 0.4988 | 0.8314 |
Schistosoma mansoni | lipoxygenase | 0.0185 | 0.5448 | 0.5131 |
Echinococcus multilocularis | peroxidasin | 0.0177 | 0.4988 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Onchocerca volvulus | Peroxidasin homolog | 0.0177 | 0.4988 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.0177 | 0.4988 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0177 | 0.4988 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.5868 | 1 |
Onchocerca volvulus | 0.0101 | 0.0651 | 0.1305 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0135 | 0.2543 | 0.3626 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0143 | 0.3017 | 0.1427 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0193 | 0.5868 | 0.4459 |
Schistosoma mansoni | peroxidasin | 0.0177 | 0.4988 | 0.4639 |
Brugia malayi | Animal haem peroxidase family protein | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0135 | 0.2543 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0193 | 0.5868 | 1 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0193 | 0.5868 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Onchocerca volvulus | 0.0177 | 0.4988 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Schistosoma mansoni | peroxidasin | 0.0177 | 0.4988 | 0.4639 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Leishmania major | farnesyltransferase beta subunit | 0.0135 | 0.2543 | 0.5 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0177 | 0.4988 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0193 | 0.5868 | 1 |
Brugia malayi | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Animal haem peroxidase family protein | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0193 | 0.5868 | 1 |
Onchocerca volvulus | 0.0177 | 0.4988 | 1 | |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0135 | 0.2543 | 0.3849 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0193 | 0.5868 | 0.4459 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0177 | 0.4988 | 0.8314 |
Brugia malayi | Blistered cuticle protein 3 | 0.0177 | 0.4988 | 0.8314 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0135 | 0.2543 | 0.3626 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.