Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0739 | 0.9524 | 0.977 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0035 | 0 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0756 | 0.9749 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0756 | 0.9749 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0035 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | = 16 uM | Antiviral activity was determined in plaque reduction assay in vero cells against HSV-1 F strain | ChEMBL. | 3871860 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.