Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.3484 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.9008 | 0.9008 |
Schistosoma mansoni | NAALADASE L peptidase (M28 family) | 0.0282 | 0.5979 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.3484 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0184 | 0.3484 | 0.5 |
Onchocerca volvulus | 0.0055 | 0.024 | 0.5 | |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.3484 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0184 | 0.3484 | 0.5 |
Echinococcus multilocularis | n acetylated alpha linked acidic dipeptidase 2 | 0.0431 | 0.9734 | 1 |
Onchocerca volvulus | 0.0055 | 0.024 | 0.5 | |
Onchocerca volvulus | Subfamily M14A unassigned peptidase homolog | 0.0055 | 0.024 | 0.5 |
Onchocerca volvulus | 0.0055 | 0.024 | 0.5 | |
Onchocerca volvulus | 0.0055 | 0.024 | 0.5 | |
Echinococcus granulosus | subfamily M14A unassigned peptidase | 0.0055 | 0.024 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0184 | 0.3484 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.6245 | 0.6245 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.