Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0267 | 0.2946 | 0.2946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0267 | 0.2946 | 0.2946 |
Entamoeba histolytica | cysteine protease, putative | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0267 | 0.2946 | 0.2946 |
Brugia malayi | Cathepsin L-like precursor | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0502 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0502 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0334 | 0.4957 | 0.2851 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.4957 | 0.2851 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0267 | 0.2946 | 0.1053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0334 | 0.4957 | 0.4957 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0267 | 0.2946 | 0.2946 |
Toxoplasma gondii | cathepsin CPL | 0.0502 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0502 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.2115 | 0.2115 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.4957 | 0.4957 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.4957 | 0.2851 |
Brugia malayi | Cathepsin L-like precursor | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Loa Loa (eye worm) | ctsf protein | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.4957 | 0.4957 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0502 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0334 | 0.4957 | 0.4957 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0239 | 0.2115 | 0.2115 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.4957 | 0.4957 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0502 | 1 | 1 |
Echinococcus granulosus | cysteine protease | 0.0267 | 0.2946 | 0.1053 |
Onchocerca volvulus | Cathepsin L homolog | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0502 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0239 | 0.2115 | 0.2115 |
Echinococcus multilocularis | cysteine protease | 0.0502 | 1 | 1 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0239 | 0.2115 | 0.2115 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0239 | 0.2115 | 0.2115 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0239 | 0.2115 | 0.2115 |
Trypanosoma cruzi | cysteine protease, putative | 0.0267 | 0.2946 | 0.2946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0502 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.4957 | 0.4957 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0334 | 0.4957 | 0.4957 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0502 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0502 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0334 | 0.4957 | 0.4957 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0502 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0502 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0502 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0502 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.4957 | 0.4957 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0267 | 0.2946 | 0.2946 |
Brugia malayi | Cathepsin L-like precursor | 0.0502 | 1 | 1 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0502 | 1 | 1 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0267 | 0.2946 | 0.2946 |
Plasmodium vivax | vivapain-3 | 0.0267 | 0.2946 | 0.2946 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0267 | 0.2946 | 0.2946 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0502 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0267 | 0.2946 | 0.1053 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0267 | 0.2946 | 0.2946 |
Plasmodium vivax | vivapain-1 | 0.0267 | 0.2946 | 0.2946 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0239 | 0.2115 | 0.2115 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0502 | 1 | 1 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0502 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0502 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0502 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0502 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0334 | 0.4957 | 0.3604 |
Echinococcus multilocularis | cathepsin L | 0.0267 | 0.2946 | 0.1053 |
Onchocerca volvulus | 0.0502 | 1 | 1 | |
Plasmodium vivax | unspecified product | 0.0267 | 0.2946 | 0.2946 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0267 | 0.2946 | 0.2946 |
Leishmania major | cathepsin L-like protease | 0.0502 | 1 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0502 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0502 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.