Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 1 % | Antiinflammatory activity in D-adjuvant induced arthiritis in rat measured by the change in body weight | ChEMBL. | 1732553 |
Inhibition (functional) | = 0 % | Antiinflammatory activity against carrageenan induced rat paw edema (CPE), dosed orally | ChEMBL. | 1732553 |
Inhibition (functional) | = 6 % | Antiinflammatory activity against D-adjuvant arthiritis in injected rat paw at the dose of 50 mg/kg by oral administration | ChEMBL. | 1732553 |
Inhibition (functional) | = 59 % | Antiinflammatory activity against D-adjuvant arthiritis in uninjected rat paw at the dose of 50 mg/kg by oral administration | ChEMBL. | 1732553 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.