Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0021 | 0.0019 | 0.0013 |
Brugia malayi | Cytochrome P450 family protein | 0.0041 | 0.0119 | 0.0119 |
Trypanosoma brucei | cytochrome P450, putative | 0.0041 | 0.0119 | 0.0202 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0021 | 0.0019 | 0.0007 |
Leishmania major | cytochrome p450-like protein | 0.0024 | 0.0037 | 0.0046 |
Brugia malayi | thymidylate synthase | 0.022 | 0.0986 | 0.0986 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0021 | 0.0019 | 0.0007 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0021 | 0.0019 | 0.0013 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0097 | 0.0085 |
Schistosoma mansoni | cytochrome P450 | 0.0024 | 0.0037 | 0.0024 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.002 | 0.0018 | 0.0006 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0024 | 0.0037 | 0.0046 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0021 | 0.0019 | 0.0007 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0021 | 0.0019 | 0.0792 |
Chlamydia trachomatis | dihydrofolate reductase | 0.2076 | 1 | 1 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0021 | 0.0019 | 0.0792 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0041 | 0.0119 | 0.0202 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.022 | 0.0986 | 0.0974 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0104 | 0.0427 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0016 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0024 | 0.0037 | 0.0024 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0041 | 0.0119 | 0.0117 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.0021 | 0.0019 | 0.0007 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0024 | 0.0037 | 0.0046 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Entamoeba histolytica | P-glycoprotein-5 | 0.0021 | 0.0019 | 0.0792 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0007 |
Schistosoma mansoni | smdr2 | 0.0021 | 0.0019 | 0.0007 |
Plasmodium vivax | multidrug resistance protein 1, putative | 0.0021 | 0.0019 | 0.0013 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0024 | 0.0037 | 0.0024 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0024 | 0.0037 | 0.0046 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.022 | 0.0986 | 0.0974 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0041 | 0.0119 | 0.0117 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.2076 | 1 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0007 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0041 | 0.0119 | 0.0107 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.1108 | 0.5301 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0097 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0024 | 0.0037 | 0.0024 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0021 | 0.0019 | 0.0792 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0044 | 0.0044 |
Brugia malayi | multidrug resistance protein 3 | 0.0021 | 0.0019 | 0.0019 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0007 |
Brugia malayi | ABC transporter family protein | 0.0021 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.008 | 0.0307 | 0.0305 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0097 | 0.0085 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0013 | 0.001 |
Echinococcus multilocularis | thymidylate synthase | 0.022 | 0.0986 | 0.0974 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0021 | 0.0019 | 0.0017 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0024 | 0.0037 | 0.0046 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0024 | 0.0037 | 0.0024 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0044 | 0.006 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0024 | 0.0037 | 0.0024 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0021 | 0.0019 | 0.0792 |
Schistosoma mansoni | dihydrofolate reductase | 0.2076 | 1 | 1 |
Leishmania major | p-glycoprotein | 0.0021 | 0.0019 | 0.0013 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0021 | 0.0019 | 0.0792 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0104 | 0.0427 | 0.0783 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.022 | 0.0986 | 0.0953 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0104 | 0.0427 | 0.0415 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.1108 | 0.5301 | 1 |
Trichomonas vaginalis | taga, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus multilocularis | 0.0024 | 0.0037 | 0.0024 | |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0024 | 0.0037 | 0.0024 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0013 | 0.5 |
Trichomonas vaginalis | abcb9, putative | 0.0021 | 0.0019 | 0.0162 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1108 | 0.5301 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0044 | 0.006 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0044 | 0.006 |
Loa Loa (eye worm) | cytochrome P450 | 0.0024 | 0.0037 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0024 | 0.0037 | 0.0024 |
Echinococcus multilocularis | dihydrofolate reductase | 0.2076 | 1 | 1 |
Schistosoma mansoni | multidrug resistance protein | 0.0021 | 0.0019 | 0.0007 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0024 | 0.0037 | 0.0024 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0013 | 0.0013 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0041 | 0.0119 | 0.0117 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0024 | 0.0037 | 0.0046 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0021 | 0.0019 | 0.0007 |
Trichomonas vaginalis | abcb9, putative | 0.0021 | 0.0019 | 0.0162 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0024 | 0.0037 | 0.0024 |
Plasmodium falciparum | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0013 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0007 |
Leishmania major | cytochrome p450-like protein | 0.0024 | 0.0037 | 0.0046 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0024 | 0.0037 | 0.0024 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0021 | 0.0019 | 0.0013 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0024 | 0.0037 | 0.0046 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0024 | 0.0037 | 0.0024 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0021 | 0.0019 | 0.0007 |
Leishmania major | cytochrome p450-like protein | 0.0041 | 0.0119 | 0.0202 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0021 | 0.0019 | 0.0007 |
Brugia malayi | Cytochrome P450 family protein | 0.0041 | 0.0119 | 0.0119 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0024 | 0.0037 | 0.0024 |
Brugia malayi | cytochrome P450 | 0.0024 | 0.0037 | 0.0037 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | ABC transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0044 | 0.006 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0021 | 0.0019 | 0.0792 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0044 | 0.006 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0024 | 0.0037 | 0.0024 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0097 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0024 | 0.0037 | 0.0024 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0097 | 0.0085 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0024 | 0.0037 | 0.0024 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.1108 | 0.5301 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0097 | 1 |
Brugia malayi | Dihydrofolate reductase | 0.2076 | 1 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0021 | 0.0019 | 0.0007 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Brugia malayi | Cytochrome P450 family protein | 0.008 | 0.0307 | 0.0307 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.2076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0044 | 0.0042 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0021 | 0.0019 | 0.0007 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0013 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Onchocerca volvulus | 0.022 | 0.0986 | 1 | |
Brugia malayi | hypothetical protein | 0.0104 | 0.0427 | 0.0427 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0044 | 0.006 |
Schistosoma mansoni | multidrug resistance protein | 0.0021 | 0.0019 | 0.0007 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0097 | 0.0085 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | thymidylate synthase | 0.022 | 0.0986 | 0.0984 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0021 | 0.0019 | 0.0017 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.1108 | 0.5301 | 1 |
Schistosoma mansoni | multidrug resistance protein | 0.0021 | 0.0019 | 0.0007 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0024 | 0.0037 | 0.0024 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0041 | 0.0119 | 0.0202 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.2076 | 1 | 1 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.002 | 0.0018 | 0.0006 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0044 | 0.006 |
Mycobacterium ulcerans | thymidylate synthase | 0.022 | 0.0986 | 0.0974 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.2076 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0044 | 0.006 |
Echinococcus granulosus | dihydrofolate reductase | 0.2076 | 1 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0021 | 0.0019 | 0.0162 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0024 | 0.0037 | 0.0024 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0097 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0013 | 0.5 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0021 | 0.0019 | 0.0007 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0097 | 0.0097 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | abcb9, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0021 | 0.0019 | 0.0007 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1108 | 0.5301 | 1 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0024 | 0.0037 | 0.0024 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0021 | 0.0019 | 0.0162 |
Trichomonas vaginalis | ABC transporter, putative | 0.0021 | 0.0019 | 0.0162 |
Echinococcus granulosus | thymidylate synthase | 0.022 | 0.0986 | 0.0974 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0024 | 0.0037 | 0.0024 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0024 | 0.0037 | 0.0024 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | 0 mg kg-1 | Dose required to inhibit bovine nasalseptum type II collagen induced arthritis in rats after administration on day 13; Not tested | ChEMBL. | 15177483 |
ED50 (functional) | = 23 mg kg-1 | Dose required to inhibit LPS (20 mg/kg, injected i.v. 1 h before dosing) induced TNF-alpha release in mice upon oral administration | ChEMBL. | 15177483 |
ED50 (functional) | = 23 mg kg-1 | Dose required to inhibit LPS (20 mg/kg, injected i.v. 1 h before dosing) induced TNF-alpha release in mice upon oral administration | ChEMBL. | 15177483 |
IC50 (binding) | = 54 uM | Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation. | ChEMBL. | 15177483 |
IC50 (binding) | = 54 uM | Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation. | ChEMBL. | 15177483 |
Inhibition (functional) | = 88 % | Inhibition of LPS (20 mg/kg, injected i.v. 1 h before dosing) induced TNF-alpha release inmice upon oral administration | ChEMBL. | 15177483 |
Inhibition (functional) | = 88 % | Inhibition of LPS (20 mg/kg, injected i.v. 1 h before dosing) induced TNF-alpha release inmice upon oral administration | ChEMBL. | 15177483 |
Swelling (functional) | = 23 % | Percent swelling of joints in rats immunized with Mycobacterium tuberculosis was determined on day 20 after 25 mg/kg peroral administration | ChEMBL. | 15177483 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.