Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.0644 | 0.2638 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | glutaminase | 0.0264 | 0.6372 | 0.6372 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | Serotonin receptor | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.0656 | 0.0656 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.0644 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | G-protein coupled receptor | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0718 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.5488 | 0.5488 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0718 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0578 | 0.0578 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0034 | 0.0656 | 0.2707 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | fmrfamide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0718 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | g-protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | TAR-binding protein | 0.0127 | 0.2975 | 0.4632 |
Brugia malayi | neuropeptide F receptor | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | myosin xvIII | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | dnaJ subfamily B | 0.041 | 1 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0127 | 0.2975 | 0.4634 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.2975 | 0.2975 |
Echinococcus multilocularis | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | adenoreceptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | histamine h1 receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0537 | 0.078 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0968 | 0.1461 |
Loa Loa (eye worm) | RNA binding protein | 0.0127 | 0.2975 | 0.4632 |
Brugia malayi | Dopamine receptor protein 1 | 0.0034 | 0.0656 | 0.0972 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0033 | 0.0644 | 0.2638 |
Brugia malayi | AKH receptor | 0.0034 | 0.0656 | 0.0972 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0106 | 0.0106 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | GnHR receptor homolog | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0033 | 0.0644 | 0.0949 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0034 | 0.0656 | 0.0972 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Brugia malayi | Dopamine receptor | 0.0034 | 0.0656 | 0.0972 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0033 | 0.0644 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Echinococcus multilocularis | serotonin receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0718 | 0.1069 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0968 | 0.0968 |
Brugia malayi | G protein-coupled receptor | 0.0034 | 0.0656 | 0.0972 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.0644 | 1 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0968 | 0.0968 |
Brugia malayi | follicle stimulating hormone receptor | 0.0034 | 0.0656 | 0.0972 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.0644 | 0.0644 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.0644 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | hypothetical protein | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0968 | 0.0968 |
Brugia malayi | Serotonin receptor | 0.0034 | 0.0656 | 0.0972 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0537 | 0.0537 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.2975 | 0.2975 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | neuropeptide F receptor | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.2975 | 0.2975 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | orexin receptor type 2 | 0.0034 | 0.0656 | 0.0656 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0718 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | sulfakinin receptor protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | glutaminase | 0.0264 | 0.6372 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0127 | 0.2975 | 0.2975 |
Echinococcus multilocularis | somatostatin receptor | 0.0034 | 0.0656 | 0.0656 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0718 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.5488 | 0.8603 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0578 | 0.0578 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0978 | 0.0978 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0454 | 0.0653 |
Echinococcus granulosus | neuropeptide s receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0718 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0034 | 0.0656 | 0.0968 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0033 | 0.0644 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0034 | 0.0656 | 0.0972 |
Mycobacterium ulcerans | glutaminase | 0.0264 | 0.6372 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0968 | 0.0968 |
Brugia malayi | G-protein coupled receptor | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0968 | 0.0968 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | serotonin receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0537 | 0.0784 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.2975 | 0.2975 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | allatostatin A receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | allatostatin A receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0127 | 0.2975 | 0.4632 |
Loa Loa (eye worm) | glutaminase 2 | 0.0264 | 0.6372 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0718 | 0.0718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | serotonin receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0034 | 0.0656 | 0.0968 |
Brugia malayi | hypothetical protein | 0.0228 | 0.5488 | 0.8604 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | Melatonin receptor type 1A | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.1338 | 0.1338 |
Echinococcus granulosus | somatostatin receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0718 | 0.0718 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0034 | 0.0656 | 0.0656 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.1176 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | ORL1-like opioid receptor | 0.0034 | 0.0656 | 0.0972 |
Echinococcus granulosus | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0644 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0968 | 0.0968 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0034 | 0.0656 | 0.2707 |
Brugia malayi | Augmenter of liver regeneration | 0.0033 | 0.0644 | 0.0953 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | opsin-like receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0578 | 0.0578 |
Brugia malayi | RNA binding protein | 0.0127 | 0.2975 | 0.4634 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0454 | 0.0648 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | fmrfamide receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | hypothetical protein | 0.041 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0127 | 0.2975 | 0.2975 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0047 | 0.0978 | 1 | |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | larval opioid receptor | 0.0034 | 0.0656 | 0.0972 |
Brugia malayi | RE15519p | 0.0034 | 0.0656 | 0.0972 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | sex peptide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | fmrfamide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | sex peptide receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0978 | 0.1481 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.5488 | 0.5488 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | TAR-binding protein | 0.0127 | 0.2975 | 0.4634 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0034 | 0.0656 | 0.0972 |
Brugia malayi | glutaminase DH11.1 | 0.0264 | 0.6372 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | g protein coupled receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | amine GPCR | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0033 | 0.0644 | 0.0644 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0033 | 0.0644 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0127 | 0.2975 | 0.2975 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | biogenic amine receptor | 0.0034 | 0.0656 | 0.0656 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0016 | 0.023 | 0.0299 |
Trichomonas vaginalis | glutaminase, putative | 0.0264 | 0.6372 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0034 | 0.0656 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0656 | 0.0972 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0034 | 0.0656 | 0.0656 |
Brugia malayi | Dopamine receptor protein 2 | 0.0034 | 0.0656 | 0.0972 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0968 | 0.0968 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0968 | 0.1465 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 | |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0978 | 0.0978 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | neuropeptide receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0034 | 0.0656 | 0.0656 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0656 | 0.0968 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0034 | 0.0656 | 0.0656 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0034 | 0.0656 | 0.0656 |
Onchocerca volvulus | 0.0034 | 0.0656 | 0.2707 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 5 mg kg-1 | Beta-adrenergic blocking potency of the compound to inhibit tachycardia in anesthetized cats | ChEMBL. | 6131134 |
ED50 (functional) | = 5 mg kg-1 | Beta-adrenergic blocking potency of the compound to inhibit tachycardia in anesthetized cats | ChEMBL. | 6131134 |
Inhibition (functional) | = 33 % | In vivo beta-adrenergic blocking potency to inhibit vasodepressor response in anesthetized cats | ChEMBL. | 6131134 |
Inhibition (functional) | = 33 % | In vivo beta-adrenergic blocking potency to inhibit vasodepressor response in anesthetized cats | ChEMBL. | 6131134 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.