Detailed information for compound 209998

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 689.634 | Formula: C26H34Cl2N8O6S2--
  • H donors: 2 H acceptors: 6 LogP: 3.68 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)N1CCN(CC1)CC(=O)Nc1sc2c(n1)cc1c(c2)sc(n1)NC(=O)CN1CCN(CC1)C(=O)OCC.[Cl-].[Cl-]
  • InChi: 1S/C26H34N8O6S2.2ClH/c1-3-39-25(37)33-9-5-31(6-10-33)15-21(35)29-23-27-17-13-18-20(14-19(17)41-23)42-24(28-18)30-22(36)16-32-7-11-34(12-8-32)26(38)40-4-2;;/h13-14H,3-12,15-16H2,1-2H3,(H,27,29,35)(H,28,30,36);2*1H/p-2
  • InChiKey: VIGBBBFBHBABAK-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis protein dispatched 1 0.0055 0.0029 0.0029
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.0023 0.0567
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0248 0.017 0.0228
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0014 0.0371
Echinococcus granulosus smad 0.0042 0.002 0.002
Brugia malayi Pre-SET motif family protein 0.0436 0.0306 0.0306
Echinococcus multilocularis cysteine protease 0.0034 0.0014 0.0014
Loa Loa (eye worm) nuclear receptor NHR-67 0.0079 0.0046 0.0046
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0002 0.0043
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Entamoeba histolytica acetyltransferase, GNAT family 0.0163 0.0108 0.522
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0002 0.0043
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0082 0.0049 0.0049
Echinococcus granulosus orexin receptor type 2 0.0027 0.0009 0.0009
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0023
Echinococcus multilocularis Niemann Pick C1 protein 0.016 0.0105 0.0105
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0004 0.0003
Brugia malayi Cytochrome P450 family protein 0.0046 0.0022 0.0022
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Plasmodium falciparum metacaspase 1 0.0093 0.0056 0.0056
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0002 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0002 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0016 0.0389
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0167 0.011 0.011
Brugia malayi hypothetical protein 0.0375 0.0262 0.0261
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0006 0.0119
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0167 0.011 0.011
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0082 0.0049 0.0049
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0066 0.0037 0.005
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0127 0.3045
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0048 0.0047
Onchocerca volvulus 0.0016 0.0001 0.0004
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0082 0.0049 0.0065
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0065 0.0037 0.0037
Echinococcus granulosus allatostatin A receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0079 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0155 0.0102 0.0102
Brugia malayi hypothetical protein 0.002 0.0004 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.0023 0.0567
Echinococcus multilocularis nibrin 0.0021 0.0005 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0066 0.0066
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0023 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0042 0.002 0.002
Leishmania major cysteine peptidase A (CPA) 0.0034 0.0014 0.0018
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0009 0.0009
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0298 0.0206 0.0206
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.0095 0.2262
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi DNA topoisomerase III 0.0255 0.0175 0.0175
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0001 0.0001
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0066 0.0066
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0047 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0008 0.0221
Echinococcus multilocularis isocitrate dehydrogenase 0.0082 0.0049 0.0049
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0042 0.002 0.002
Brugia malayi neuropeptide F receptor 0.0027 0.0009 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0167 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0027 0.0009 0.0231
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) transcription factor SMAD2 0.0617 0.0438 0.0438
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0043 0.0043
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0002 0.0043
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0003 0.0054
Onchocerca volvulus Bile acid receptor homolog 0.0167 0.011 0.3142
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0043 0.0057
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) DNA topoisomerase III 0.0255 0.0175 0.0175
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0167 0.011 0.011
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0002 0.0043
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.0205 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.03 0.0208 0.0279
Brugia malayi G-protein coupled receptor 0.0027 0.0009 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0167 0.011 0.011
Brugia malayi Glycosyl hydrolases family 31 protein 0.0047 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0052 0.0027 0.0027
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0008 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0102 0.0101
Schistosoma mansoni importin beta-1 0.0059 0.0032 0.0032
Leishmania major GTP-binding protein, putative 0.0043 0.0021 0.0027
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.0072 0.0072
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0001 0.0006
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0495 0.035 0.8704
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Echinococcus granulosus neuropeptide receptor A26 0.0923 0.0661 0.0661
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0004 0.0004
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0018 0.0018
Brugia malayi jmjC domain containing protein 0.0042 0.002 0.0019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0023 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0014 0.0328
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.002 0.002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0223 0.0152 0.0152
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0172
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0005 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Mycobacterium ulcerans putative regulatory protein 0.0186 0.0125 0.2978
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0587 0.0416 0.0416
Leishmania major DNA polymerase eta, putative 0.0076 0.0044 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0049 0.0025 0.1167
Loa Loa (eye worm) hypothetical protein 0.0372 0.026 0.026
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.008 0.1899
Mycobacterium ulcerans hypothetical protein 0.0023 0.0006 0.0127
Schistosoma mansoni tyrosine kinase 0.0247 0.0169 0.0169
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0002 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Echinococcus granulosus tar DNA binding protein 0.0064 0.0036 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0065 0.0037 0.0902
Brugia malayi latrophilin 2 splice variant baaae 0.0112 0.0071 0.007
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0024 0.0031
Schistosoma mansoni DNA topoisomerase type I 1.0224 0.7431 0.7431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0043 0.1063
Mycobacterium ulcerans DNA topoisomerase I 0.0248 0.017 0.407
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0002 0.0043
Loa Loa (eye worm) pax transcription factor protein 2 0.0493 0.0348 0.0348
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0009 0.0009
Trypanosoma brucei polo-like protein kinase 0.0198 0.0133 0.0179
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Leishmania major DNA topoisomerase type IB small subunit 0.4961 0.36 0.4845
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0043 0.1063
Onchocerca volvulus 0.0495 0.035 1
Trichomonas vaginalis guanylate cyclase, putative 0.0065 0.0037 0.0902
Brugia malayi Serotonin receptor 0.0027 0.0009 0.0008
Brugia malayi serine/threonine-protein kinase plk-2 0.0198 0.0133 0.0133
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0436 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Schistosoma mansoni neuropeptide receptor 0.0027 0.0009 0.0009
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0154 0.0206
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0016 0.0001 0.0004
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0009 0.0009
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.019 0.0127 0.0127
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0082 0.0049 0.0049
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0025 0.0025
Echinococcus granulosus GPCR family 2 0.0052 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0083 0.005 0.005
Onchocerca volvulus 0.0027 0.0009 0.0231
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0026 0.0026
Echinococcus granulosus cathepsin L 0.0017 0.0002 0.0002
Onchocerca volvulus Huntingtin homolog 0.0375 0.0262 0.7483
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0004 0.0004
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0041 0.0041
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Schistosoma mansoni flap endonuclease-1 0.0024 0.0006 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0005 0.0004
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0198 0.0133 0.0179
Loa Loa (eye worm) hypothetical protein 0.0088 0.0053 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0051 0.0026 0.0738
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0036 0.0036
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0002
Schistosoma mansoni DNA ligase IV 0.0021 0.0005 0.0005
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0005 0.0006
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0006 0.0248
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 1.0224 0.7431 1
Trypanosoma cruzi metacaspase, putative 0.0093 0.0056 0.0075
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0002 0.0043
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0023 0.0023
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0079 0.0046 0.0046
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0297 0.0205 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0005 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0037 0.0902
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0023 0.0563
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0009 0.0009
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0128 0.0082 0.0082
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.007 0.004 0.004
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0173
Trypanosoma brucei metacaspase 0.0093 0.0056 0.0075
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0152 0.01 0.4951
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Mycobacterium ulcerans short-chain type oxidoreductase 0.0016 0.0001 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0167 0.011 0.011
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0036 0.0036
Echinococcus granulosus jun protein 0.0087 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0002 0.0043
Echinococcus multilocularis cysteine protease 0.0034 0.0014 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.015 0.0098 0.0098
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0023 0.003
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis 0.0399 0.028 0.028
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0018 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0009 0.0193
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus ferritin 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0002 0.0043
Brugia malayi hypothetical protein 0.0088 0.0053 0.0053
Brugia malayi GnHR receptor homolog 0.0027 0.0009 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.0023 0.0567
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Trypanosoma brucei PAB1-binding protein , putative 0.0155 0.0102 0.0136
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.002 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Brugia malayi hypoxia-induced factor 1 0.0778 0.0556 0.0555
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis JmjC domain containing protein 4 0.0042 0.002 0.002
Trypanosoma brucei MATE efflux family protein, putative 0.007 0.004 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Onchocerca volvulus 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Leishmania major alpha glucosidase II subunit, putative 0.0047 0.0023 0.0031
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.019 0.0127 0.0171
Echinococcus granulosus Smad4 0.0042 0.002 0.002
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0008 0.0177
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0003
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0024 0.0024
Echinococcus granulosus hypothetical protein 0.0743 0.053 0.053
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0245 0.0167 0.0167
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0021 0.0027
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0043 0.0043
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0009 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0009 0.0009
Trichomonas vaginalis glutaminase, putative 0.0311 0.0215 0.5354
Echinococcus granulosus lysine specific demethylase 6a 0.0042 0.002 0.002
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0036 0.0036
Echinococcus granulosus Nuclear hormone receptor HR96 0.0079 0.0046 0.0046
Entamoeba histolytica DNA topoisomerase III, putative 0.0248 0.017 0.8267
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0198 0.0133 0.0133
Onchocerca volvulus 0.0027 0.0009 0.0231
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0056 0.003 0.003
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0024 0.0024
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0004 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0005 0.0006
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0071 0.1681
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0016 0.0001 0.0003
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0016 0.0001 0.0003
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Echinococcus multilocularis caspase 8 0.0093 0.0056 0.0056
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0005 0.0095
Toxoplasma gondii DNA topoisomerase 2, putative 0.0056 0.003 0.003
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0007
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0001
Brugia malayi RNA binding protein 0.0064 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0116 0.0116
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0103
Brugia malayi Nuclear hormone receptor E75 0.0079 0.0046 0.0046
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0027 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0081 0.0048 0.0048
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis serotonin receptor 0.015 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.0923 0.0661 0.0661
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0002 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0004
Echinococcus granulosus dna polymerase kappa 0.0102 0.0064 0.0064
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0002 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0167 0.011 0.011
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0039 0.0052
Schistosoma mansoni adenoreceptor 0.0027 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0064 0.0036 0.1006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Echinococcus granulosus cysteine protease 0.0017 0.0002 0.0002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0043 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0226 0.0154 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0217
Onchocerca volvulus 0.0129 0.0083 0.2368
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0079 0.0046 0.1307
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0066 0.0066
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0002 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0167 0.011 0.011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0043 0.0043
Onchocerca volvulus 0.0082 0.0049 0.1378
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0014 0.0014
Brugia malayi jmjC domain containing protein 0.0042 0.002 0.0019
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0001
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0004 0.0004
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0082 0.0049 0.0065
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus g protein coupled receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0002 0.0031
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0001
Loa Loa (eye worm) isocitrate dehydrogenase 0.0082 0.0049 0.0049
Onchocerca volvulus 0.0027 0.0009 0.0231
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0071 0.0041 0.1003
Brugia malayi nuclear hormone receptor 0.0167 0.011 0.011
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0001 0.0003
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0128 0.0082 0.0082
Leishmania major DNA topoisomerase IB, large subunit 1.0224 0.7431 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0079 0.0046 0.1307
Mycobacterium tuberculosis Probable monooxygenase 0.0027 0.0008 0.0186
Brugia malayi Inositol-1 0.0152 0.01 0.0099
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0073 0.0042 0.1043
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.061 0.0433 0.0433
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0075 0.0043 0.0043
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0052 0.0027 0.0027
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0056 0.003 0.003
Schistosoma mansoni globin X 0.0027 0.0008 0.0008
Brugia malayi Protein kinase domain containing protein 0.025 0.0171 0.017
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0065 0.0037 0.0902
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0049 0.0049
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0016 0.0001 0.0004
Brugia malayi hypothetical protein 0.0021 0.0005 0.0004
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0102 0.0064 0.1573
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0002 0.0043
Giardia lamblia DNA topoisomerase III 0.0129 0.0083 0.4036
Plasmodium vivax metacaspase 1, putative 0.0093 0.0056 0.0056
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Schistosoma mansoni microtubule-associated protein tau 0.1375 0.099 0.099
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) cytochrome P450 0.0018 0.0002 0.0002
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0079
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0021 0.002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0002 0.0043
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0002 0.0043
Schistosoma mansoni hypothetical protein 0.0112 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0059 0.0032 0.0032
Trichomonas vaginalis DNA polymerase eta, putative 0.0102 0.0064 0.1573
Entamoeba histolytica hypothetical protein 0.0016 0.0001 0.0006
Giardia lamblia DNA damage repair protein 0.0023 0.0006 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.0006
Onchocerca volvulus 0.0027 0.0009 0.0231
Loa Loa (eye worm) hypothetical protein 0.1466 0.1056 0.1056
Brugia malayi nuclear receptor RXR 0.0088 0.0053 0.0053
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0008 0.0008
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0072 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Echinococcus multilocularis musashi 0.0082 0.0049 0.0049
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0036 0.0036
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0064 0.0036 0.0036
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0009 0.0009
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Brugia malayi Cytochrome P450 family protein 0.0018 0.0002 0.0002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0167 0.011 0.011
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0056 0.003 0.1466
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0567 0.0402 0.0401
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0014 0.0014
Toxoplasma gondii thioredoxin reductase 0.0049 0.0025 0.0025
Onchocerca volvulus 0.0027 0.0008 0.0221
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0002 0.0002
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.015 0.0098 0.0098
Leishmania major mitochondrial DNA polymerase beta 0.03 0.0208 0.0279
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0174 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus neuropeptide s receptor 0.0923 0.0661 0.0661
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0167 0.011 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0009 0.0193
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0167 0.011 0.011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Schistosoma mansoni nuclear hormone receptor 0.0079 0.0046 0.0046
Brugia malayi Bromodomain containing protein 0.0044 0.0021 0.0021
Loa Loa (eye worm) glutathione reductase 0.0049 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.1039 0.0746 0.0746
Schistosoma mansoni hypothetical protein 0.007 0.004 0.004
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0001 0.0025
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Echinococcus granulosus JmjC domain containing protein 4 0.0042 0.002 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0007
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0009 0.0009
Brugia malayi jmjC domain containing protein 0.0042 0.002 0.0019
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0005 0.0095
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0006 0.0006
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Brugia malayi Thioredoxin reductase 0.0049 0.0025 0.0024
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0082 0.0048 0.0065
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0198 0.0133 0.0133
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0042 0.002 0.002
Entamoeba histolytica cysteine proteinase 1, putative 0.0017 0.0002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0023 0.1092
Echinococcus multilocularis phd:f box containing protein 0.0042 0.002 0.002
Schistosoma mansoni caspase-7 (C14 family) 0.0179 0.0119 0.0119
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0011
Mycobacterium ulcerans DNA gyrase subunit B 0.0056 0.003 0.0708
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0079 0.0046 0.0046
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0025 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0036 0.0036
Schistosoma mansoni ferritin 0.0026 0.0008 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0604 0.0429 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0009 0.0009
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0088 0.0053 0.0053
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0136 0.0088 0.2103
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0017 0.0002 0.0002
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Plasmodium falciparum histone acetyltransferase GCN5 0.0163 0.0108 0.0107
Plasmodium falciparum cysteine proteinase falcipain 1 0.0017 0.0002 0.0001
Mycobacterium ulcerans hypothetical protein 0.0026 0.0008 0.0177
Schistosoma mansoni axis inhibition protein axin 0.002 0.0004 0.0004
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0167 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Brugia malayi isocitrate dehydrogenase 0.0082 0.0049 0.0048
Trichomonas vaginalis inositol monophosphatase, putative 0.0152 0.01 0.2475
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0248 0.017 0.0228
Echinococcus multilocularis lysine specific demethylase 5A 0.0158 0.0104 0.0104
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0002 0.0043
Mycobacterium leprae Probable oxidoreductase 0.0016 0.0001 0.0003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0037 0.0049
Schistosoma mansoni single-minded 0.0251 0.0172 0.0172
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Onchocerca volvulus Glucosylceramidase homolog 0.0372 0.026 0.7423
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.002
Echinococcus granulosus cathepsin l1 0.0034 0.0014 0.0014
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.002 0.002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0002 0.0083
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0079 0.0046 0.0046
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0023 0.003
Onchocerca volvulus 0.0027 0.0008 0.0221
Echinococcus granulosus nuclear receptor nhr 48 0.0079 0.0046 0.0046
Echinococcus multilocularis cathepsin L 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0079 0.0046 0.0046
Giardia lamblia Histone acetyltransferase GCN5 0.0163 0.0108 0.522
Loa Loa (eye worm) hypothetical protein 0.0844 0.0603 0.0603
Brugia malayi Flap endonuclease-1 0.0026 0.0008 0.0008
Schistosoma mansoni DNA topoisomerase II 0.0056 0.003 0.003
Leishmania major DNA topoisomerase III, putative 0.0129 0.0083 0.0111
Schistosoma mansoni hypothetical protein 0.1311 0.0944 0.0944
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0061 0.0061
Brugia malayi steroid hormone receptor 0.0167 0.011 0.011
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.0127 0.0127
Loa Loa (eye worm) DR-78 0.0079 0.0046 0.0046
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0004 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0003 0.0054
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0022 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0009 0.0009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0026
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.007 0.004 0.004
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Echinococcus granulosus flap endonuclease 1 0.0026 0.0008 0.0008
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi Serotonin receptor 0.0027 0.0009 0.0008
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0004 0.0004
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0006
Echinococcus granulosus axis inhibition protein axin 0.002 0.0004 0.0004
Plasmodium vivax JmjC domain containing protein 0.0042 0.002 0.0019
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0617 0.0438 0.0438
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0299 0.0207 0.0206
Leishmania major trypanothione reductase 0.0049 0.0025 0.0033
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0001 0.0005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Plasmodium falciparum importin beta, putative 0.0059 0.0032 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0082 0.0049 0.0049
Giardia lamblia DNA topoisomerase III 0.0248 0.017 0.8267
Brugia malayi MH2 domain containing protein 0.0042 0.002 0.0019
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0043 0.0057
Schistosoma mansoni terminal deoxycytidyl transferase 0.0075 0.0043 0.0043
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0001
Trichomonas vaginalis ferritin, putative 0.0026 0.0008 0.0196
Loa Loa (eye worm) hypothetical protein 0.0084 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Schistosoma mansoni tsg101-related 0.006 0.0033 0.0033
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0079
Schistosoma mansoni nuclear receptor 0.0079 0.0046 0.0046
Giardia lamblia DINP protein human, muc B family 0.0082 0.0048 0.2331
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0002 0.005
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0009 0.0009
Schistosoma mansoni opsin-like receptor 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0034 0.0014 0.0371
Trypanosoma cruzi DNA topoisomerase III, putative 0.0255 0.0175 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Leishmania major cytochrome p450-like protein 0.0046 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0032 0.0012 0.0012
Echinococcus multilocularis inositol monophosphatase 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0086 0.0052 0.0052
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0167 0.011 0.011
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0016 0.0001 0.0008
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0008 0.0376
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0045 0.0045
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0043 0.0043
Brugia malayi Dopamine receptor protein 1 0.0027 0.0009 0.0008
Leishmania major hypothetical protein, conserved 0.007 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0023 0.0563
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0604 0.0429 0.0429
Schistosoma mansoni hypothetical protein 0.0052 0.0027 0.0027
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0017 0.0017
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Leishmania major cathepsin L-like protease 0.0034 0.0014 0.0018
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0001 0.0006
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0066 0.0066
Trypanosoma cruzi polo-like protein kinase, putative 0.0198 0.0133 0.0179
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0005 0.0192
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0048 0.0048
Trypanosoma cruzi polo-like protein kinase, putative 0.0198 0.0133 0.0179
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0002 0.0043
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0016 0.0021
Echinococcus multilocularis geminin 0.1039 0.0746 0.0746
Schistosoma mansoni tsg101-related 0.006 0.0033 0.0033
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0002 0.0033
Loa Loa (eye worm) glutaminase 2 0.0311 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0002 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.0053 0.0053
Echinococcus multilocularis muscleblind protein 0.061 0.0433 0.0433
Schistosoma mansoni hypothetical protein 0.0098 0.006 0.006
Onchocerca volvulus 0.0186 0.0125 0.3549
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.0083 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0016 0.0001 0.0004
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0052 0.0027 0.0027
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0052 0.0027 0.0027
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0587 0.0417 1
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0082 0.0049 0.0049
Onchocerca volvulus Alhambra homolog 0.0029 0.0011 0.0282
Leishmania major cathepsin L-like protease 0.0128 0.0083 0.0111
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Onchocerca volvulus 0.0027 0.0009 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0037 0.0902
Echinococcus multilocularis nuclear receptor nhr 48 0.0079 0.0046 0.0046
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0005 0.0006
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0004 0.0005
Entamoeba histolytica hypothetical protein 0.0048 0.0024 0.1129
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0001 0.0033
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0102 0.0136
Onchocerca volvulus Globin homolog 0.0027 0.0008 0.0221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Plasmodium vivax DNA topoisomerase 3, putative 0.0248 0.017 0.0169
Giardia lamblia Short-chain dehydrogenase, putative 0.0016 0.0001 0.0006
Brugia malayi Pax transcription factor protein 2 0.0493 0.0348 0.0347
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0002 0.0051
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Schistosoma mansoni zinc finger protein 0.0079 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0026 0.0026
Echinococcus multilocularis dnaJ subfamily B 0.1311 0.0944 0.0944
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0002 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis snurportin 1 0.0628 0.0446 0.0446
Echinococcus granulosus neuropeptide receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0009 0.0231
Toxoplasma gondii aldehyde dehydrogenase 0.019 0.0127 0.0127
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.0023 0.0567
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Echinococcus multilocularis 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0005 0.0126
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Brugia malayi nuclear hormone receptor 0.0079 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0011 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0009 0.0009
Mycobacterium tuberculosis Conserved hypothetical protein 0.0158 0.0104 0.249
Leishmania major DNA topoisomerase III, putative 0.0298 0.0206 0.0276
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0002 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0217
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0064 0.0085
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0065 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0081 0.0048 0.0048
Schistosoma mansoni dep domain containing protein 0.0018 0.0002 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0009 0.0009
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0026 0.0035
Brugia malayi putative neuropeptide receptor 0.0027 0.0009 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.0167 0.011 0.011
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Leishmania major hypothetical protein, conserved 0.007 0.004 0.0053
Schistosoma mansoni survival motor neuron protein 0.0299 0.0207 0.0207
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Plasmodium vivax vivapain-2 0.0034 0.0014 0.0013
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0002 0.0002
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0022 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0093 0.0056 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Echinococcus granulosus lamin dm0 0.0082 0.0049 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Mycobacterium ulcerans hypothetical protein 0.0158 0.0104 0.249
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0066 0.0037 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0002 0.0043
Schistosoma mansoni myoglobin 1 0.0027 0.0008 0.0008
Brugia malayi Cathepsin L-like precursor 0.0023 0.0005 0.0005
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0008 0.0011
Echinococcus granulosus expressed protein 0.0387 0.0271 0.0271
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0024 0.0024
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0036 0.0036
Onchocerca volvulus 0.0068 0.0039 0.1086
Brugia malayi Nuclear hormone receptor E75 0.0079 0.0046 0.0046
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0042 0.002 0.0026
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0141
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0043 0.1027
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0071 0.1681
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0072 0.0041 0.0041
Brugia malayi hypothetical protein 0.01 0.0062 0.0061
Echinococcus multilocularis microtubule associated protein 2 0.1375 0.099 0.099
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0001 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0069 0.004 0.004
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0009 0.0011
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0009 0.0008
Trypanosoma brucei metacaspase 5, putative 0.0093 0.0056 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Plasmodium vivax SET domain protein, putative 0.0065 0.0036 0.0035
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.002 0.002
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0022 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0019 0.0019
Brugia malayi hypothetical protein 0.0079 0.0046 0.0046
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Onchocerca volvulus 0.0034 0.0014 0.0371
Schistosoma mansoni hypothetical protein 0.0299 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Plasmodium vivax vivapain-1 0.0017 0.0002 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0043 0.0043
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0043 0.0043
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0008 0.0008
Echinococcus multilocularis inositol monophosphatase 1 0.0152 0.01 0.01
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0006 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0014 0.0632
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Brugia malayi DNA topoisomerase III beta-1 0.0129 0.0083 0.0083
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.0014 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0009 0.0011
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0004 0.0004
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0172
Echinococcus granulosus microtubule associated protein 2 0.1375 0.099 0.099
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0009 0.0009
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0002 0.0043
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0001
Plasmodium falciparum phd finger protein, putative 0.0029 0.0011 0.001
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0017 0.0017
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0001 0.0039
Schistosoma mansoni pap-inositol-14-phosphatase 0.0016 0.0001 0.0001
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0009 0.0193
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0009 0.0009
Echinococcus granulosus inositol monophosphatase 0.0016 0.0001 0.0001
Plasmodium vivax DNA topoisomerase II, putative 0.0056 0.003 0.0029
Trypanosoma brucei membrane transporter protein, putative 0.007 0.004 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Onchocerca volvulus 0.0065 0.0036 0.1017
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0082 0.0049 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0004 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0036 0.0036
Brugia malayi MH2 domain containing protein 0.0617 0.0438 0.0438
Echinococcus granulosus fmrfamide receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Brugia malayi hypothetical protein 0.1466 0.1056 0.1056
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0033 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Giardia lamblia Hypothetical protein 0.0016 0.0001 0.0006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0093 0.0056 0.0056
Loa Loa (eye worm) Smad1 0.0042 0.002 0.002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0002 0.0003
Schistosoma mansoni smad1 5 8 and 0.0042 0.002 0.002
Echinococcus multilocularis ferritin 0.0026 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0103
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0002 0.0043
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0198 0.0133 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0075 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Brugia malayi hypothetical protein 0.0844 0.0603 0.0603
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0009 0.0011
Mycobacterium ulcerans hypothetical protein 0.0026 0.0008 0.0177
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0152 0.01 0.2475
Schistosoma mansoni hypothetical protein 0.0052 0.0027 0.0027
Entamoeba histolytica hypothetical protein 0.0223 0.0152 0.7374
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0052 0.0027 0.0027
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0082 0.0049 0.0048
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0002 0.005
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0017 0.0017
Echinococcus granulosus intermediate filament protein 0.0082 0.0049 0.0049
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0002 0.0043
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0009 0.0008
Trypanosoma brucei unspecified product 0.0095 0.0059 0.0078
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.0014 0.0013
Onchocerca volvulus 0.0299 0.0207 0.5904
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0003 0.0003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0069 0.004 0.004
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0071 0.1681
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0093 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0587 0.0417 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Plasmodium falciparum glutathione reductase 0.0049 0.0025 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0004
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0046 0.0023 0.0023
Plasmodium falciparum JmjC domain-containing protein, putative 0.0042 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0027 0.0008 0.0008
Echinococcus multilocularis protein patched 0.0048 0.0024 0.0024
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0049 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0002 0.0033
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0025 0.0025
Brugia malayi glutathione reductase 0.0049 0.0025 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Schistosoma mansoni DNA topoisomerase type I 1.0224 0.7431 0.7431
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0001 0.0001
Echinococcus granulosus axis inhibition protein axin 0.002 0.0004 0.0004
Echinococcus granulosus peregrin 0.0044 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0173
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0088 0.0053 0.0053
Echinococcus granulosus inositol monophosphatase 1 0.0152 0.01 0.01
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0001 0.0019
Echinococcus granulosus Niemann Pick C1 protein 0.016 0.0105 0.0105
Entamoeba histolytica ABC transporter, putative 0.002 0.0004 0.016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0041 0.0041
Brugia malayi nuclear receptor NHR-88 0.0167 0.011 0.011
Brugia malayi PAS domain containing protein 0.0251 0.0172 0.0172
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypoxia-induced factor 1 0.0778 0.0556 0.0556
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Leishmania major cathepsin L-like protease 0.0034 0.0014 0.0018
Schistosoma mansoni smad 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0034 0.0014 0.0371
Brugia malayi hypothetical protein 0.0223 0.0152 0.0151
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0061 0.0061
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0008 0.0184
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Schistosoma mansoni topbp1 0.0021 0.0005 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.007 0.007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Leishmania major DNA damage repair protein, putative 0.0023 0.0006 0.0007
Trypanosoma brucei membrane transporter protein, putative 0.007 0.004 0.0053
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0006 0.0005
Brugia malayi Smad1 0.0042 0.002 0.0019
Echinococcus multilocularis neutral alpha glucosidase AB 0.0047 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0004 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0016 0.0001 0.0005
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0022 0.003
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0016 0.0389
Trypanosoma cruzi metacaspase, putative 0.0093 0.0056 0.0075
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.0093 0.0124
Brugia malayi ImpB/MucB/SamB family protein 0.0075 0.0043 0.0043
Brugia malayi PHD-finger family protein 0.0029 0.0011 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0009 0.0009
Schistosoma mansoni caspase-3 (C14 family) 0.0245 0.0167 0.0167
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0008 0.0184
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0005 0.0103
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0082 0.0049 0.0065
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0021 0.0021
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0153 0.0101 0.0101
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.0095 0.2262
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0008 0.0197
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0052 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.004 0.0053
Entamoeba histolytica hypothetical protein 0.0223 0.0152 0.7374
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0128 0.0082 0.1956
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0024 0.0581
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0016 0.0001 0.0003
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0093 0.0056 0.0056
Brugia malayi hypothetical protein 0.0088 0.0053 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0061 0.1502
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Mycobacterium ulcerans glutaminase 0.0311 0.0215 0.5159
Brugia malayi Importin beta-1 subunit 0.0059 0.0032 0.0031
Echinococcus multilocularis serotonin receptor 0.015 0.0098 0.0098
Trypanosoma brucei ABC transporter, putative 0.002 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0069 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0046 0.0023 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Brugia malayi cytochrome P450 0.0018 0.0002 0.0002
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0002 0.0002
Schistosoma mansoni kinase 0.0101 0.0063 0.0063
Leishmania major hypothetical protein, conserved 0.0042 0.002 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0006
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0002 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0127 0.3045
Brugia malayi hypothetical protein 0.0072 0.0041 0.0041
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0002 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0001 0.0001
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0017 0.0002 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.002 0.002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0009 0.0193
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0016 0.0001 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0023 0.0563
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0008 0.0177
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0071 0.1681
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0065 0.0037 0.0037
Trichomonas vaginalis hypothetical protein 0.0035 0.0014 0.035
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Schistosoma mansoni ferritin 0.0026 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0022 0.0022
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0023 0.0006 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0167 0.011 0.011
Schistosoma mansoni ran 0.0043 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Entamoeba histolytica Ran family GTPase 0.0043 0.0021 0.0972
Brugia malayi jmjC domain containing protein 0.0219 0.0149 0.0148
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0009 0.0231
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0001 0.0001
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0001 0.0038
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0004 0.0004
Schistosoma mansoni jumonji domain containing protein 0.0199 0.0134 0.0134
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0016 0.0001 0.0001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0001 0.0001
Onchocerca volvulus Cathepsin F homolog 0.0034 0.0014 0.0371
Onchocerca volvulus 0.0079 0.0046 0.1307
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0047 0.0023 0.1101
Echinococcus multilocularis smad 0.0042 0.002 0.002
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0003
Echinococcus multilocularis neuropeptide receptor A26 0.0923 0.0661 0.0661
Echinococcus multilocularis lysosomal alpha glucosidase 0.0153 0.0101 0.0101
Schistosoma mansoni phd/f-box containing protein 0.0042 0.002 0.002
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0005 0.0103
Echinococcus multilocularis expressed protein 0.0026 0.0008 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Echinococcus granulosus transcription factor Dp 1 0.004 0.0018 0.0018
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0167 0.011 0.011
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0003 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0002 0.005
Schistosoma mansoni smad1 5 8 and 0.0042 0.002 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0016 0.0001 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0222
Plasmodium vivax vivapain-2 0.0034 0.0014 0.0013
Brugia malayi jmjC domain containing protein 0.0165 0.0109 0.0109
Plasmodium falciparum thioredoxin reductase 0.0017 0.0001 0.0001
Echinococcus multilocularis rho GTPase activating protein 20 0.0255 0.0175 0.0175
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0021 0.0021
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.002 0.002
Echinococcus multilocularis kelch ECH associated protein 1 0.0097 0.006 0.006
Brugia malayi MH1 domain containing protein 0.0042 0.002 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0004 0.0004
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0255 0.0175 0.0175
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0009 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0009 0.0008
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0047 0.0023 0.0023
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0017 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0004 0.0004
Toxoplasma gondii SWI2/SNF2-containing protein 0.0042 0.002 0.002
Chlamydia trachomatis DNA gyrase subunit B 0.0056 0.003 0.1472
Toxoplasma gondii DNA topoisomerase family protein 0.0248 0.017 0.017
Schistosoma mansoni amine GPCR 0.0027 0.0009 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0056 0.0056
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Echinococcus granulosus expressed conserved protein 0.0105 0.0066 0.0066
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0167 0.011 0.011
Leishmania major DNA polymerase eta, putative 0.0127 0.0082 0.011
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0023 0.0023
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0002 0.0043
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0009
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0001 0.0001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0493 0.0348 0.9947
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0014 0.0014
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0056 0.003 0.0843
Trypanosoma brucei unspecified product 0.0051 0.0027 0.0035
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0032 0.0032
Schistosoma mansoni ran 0.0043 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) glutaminase 0.0311 0.0215 0.0215
Echinococcus multilocularis Smad4 0.0042 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0088 0.0053 0.0053
Schistosoma mansoni lamin 0.0082 0.0049 0.0049
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0021 0.002
Trypanosoma brucei DNA polymerase eta, putative 0.0127 0.0082 0.011
Schistosoma mansoni smad1 5 8 and 0.0042 0.002 0.002
Mycobacterium tuberculosis Conserved protein 0.0026 0.0008 0.0177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.0011
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0066 0.0066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0009 0.0009
Trypanosoma cruzi membrane transporter protein, putative 0.007 0.004 0.0053
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0082 0.0048 0.1148
Treponema pallidum DNA ligase (lig) 0.0021 0.0005 0.0155
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0007
Schistosoma mansoni amine GPCR 0.0027 0.0009 0.0009
Echinococcus multilocularis sex peptide receptor 0.0027 0.0009 0.0009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0178 0.0118 0.0118
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0002 0.0002
Echinococcus multilocularis oxidoreductase 0.0016 0.0001 0.0001
Mycobacterium ulcerans dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0219 0.0149 0.0149
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0064 0.1512
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Leishmania major cathepsin L-like protease 0.0128 0.0083 0.0111
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0046 0.0023 0.0023
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0056 0.003 0.004
Schistosoma mansoni jun-related protein 0.007 0.004 0.004
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0066 0.0066
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0016 0.0389
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0023 0.0031
Plasmodium vivax importin-beta 2, putative 0.0059 0.0032 0.0031
Schistosoma mansoni opsin-like receptor 0.0027 0.0009 0.0009
Brugia malayi hypothetical protein 0.002 0.0004 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus multilocularis transfer RNA-Lys 0.0186 0.0125 0.0125
Onchocerca volvulus 0.0065 0.0037 0.1031
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0052 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0002 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0009 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0178 0.0118 0.0118
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0128 0.0082 0.0082
Brugia malayi Dopamine receptor 0.0027 0.0009 0.0008
Brugia malayi hypothetical protein 0.0068 0.0039 0.0038
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0178 0.0118 0.0118
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0004 0.0004
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0009 0.0193
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0009 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0086 0.0052 0.0052
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0001 0.0001
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0046 0.0023 0.0023
Schistosoma mansoni ferritin 0.0026 0.0008 0.0008
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0002 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0003 0.0054
Brugia malayi CXXC zinc finger family protein 0.012 0.0076 0.0076
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0257 0.0176 0.0176
Brugia malayi CHE-14 protein 0.0048 0.0024 0.0024
Brugia malayi jmjC domain containing protein 0.0042 0.002 0.0019
Leishmania major cathepsin L-like protease 0.0034 0.0014 0.0018
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0009 0.0009
Brugia malayi AKH receptor 0.0027 0.0009 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0056 0.003 0.003
Brugia malayi Cathepsin L-like precursor 0.0023 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0056 0.003 0.1404
Loa Loa (eye worm) hypothetical protein 0.0088 0.0053 0.0053
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0021 0.0021
Schistosoma mansoni lamin 0.0082 0.0049 0.0049
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.0241
Echinococcus granulosus caspase 8 0.0093 0.0056 0.0056
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0152 0.01 0.2475
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0002 0.0043
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0011 0.0011
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0005 0.0005
Brugia malayi nuclear receptor RXR 0.0079 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus multilocularis lamin 0.0082 0.0049 0.0049
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0129 0.0083 0.0083
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.019 0.0127 0.0127
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0167 0.011 0.011
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.002 0.002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0043 0.0057
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0167 0.011 0.011
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0017 0.0016
Trichomonas vaginalis adenylate cyclase, putative 0.0065 0.0037 0.0902
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0002 0.0002
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0082 0.0049 0.0065
Echinococcus multilocularis dna polymerase kappa 0.0102 0.0064 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Echinococcus granulosus serotonin receptor 0.0027 0.0009 0.0009
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0011 0.0011
Schistosoma mansoni biogenic amine receptor 0.0027 0.0009 0.0009
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0009 0.0193
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0002 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0036 0.0036
Plasmodium falciparum glutathione reductase 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0036 0.0036
Schistosoma mansoni histamine h1 receptor 0.0027 0.0009 0.0009
Echinococcus granulosus oxidoreductase 0.0016 0.0001 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0003 0.0003
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0008 0.0375
Schistosoma mansoni inositol monophosphatase 0.0152 0.01 0.01
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Onchocerca volvulus Sepiapterin reductase homolog 0.0016 0.0001 0.0004
Brugia malayi tailless protein 0.0079 0.0046 0.0046
Leishmania major DNA topoisomerase 1A 0.0248 0.017 0.0228
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0016 0.0001 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0082 0.0049 0.0049
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0005 0.0005
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0006 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0002 0.0043
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0023 0.0006 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0002 0.0001
Onchocerca volvulus 0.0034 0.0014 0.0371
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.0119
Trypanosoma brucei DNA topoisomerase III, putative 0.0129 0.0083 0.0111
Echinococcus granulosus ecdysone induced protein 78C 0.0167 0.011 0.011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0061 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0002 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0152 0.01 0.2382
Schistosoma mansoni phosphatidylserine receptor 0.0042 0.002 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0164 0.0108 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0167 0.011 0.011
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0006 0.0119
Echinococcus multilocularis apoptotic protease activating factor 1 0.0086 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0032 0.0032
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.004 0.0053
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0065 0.0037 0.0902
Schistosoma mansoni hypothetical protein 0.0628 0.0446 0.0446
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0128 0.0082 0.0082
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Loa Loa (eye worm) globin family protein 0.0027 0.0008 0.0008
Brugia malayi Protein kinase domain containing protein 0.0174 0.0116 0.0116
Onchocerca volvulus 0.0167 0.011 0.3142
Brugia malayi N-terminal motif family protein 0.0372 0.026 0.026
Plasmodium falciparum DNA gyrase subunit B 0.0056 0.003 0.0029
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0009 0.0231
Schistosoma mansoni hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0088 0.0053 0.0053
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0056 0.003 0.0843
Schistosoma mansoni bromodomain containing protein 0.0022 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0009 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.0127 0.0127
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0005 0.0006
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0129 0.0083 0.0083
Trypanosoma cruzi metacaspase 5, putative 0.0093 0.0056 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0223 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0005
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0001
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0079 0.0046 0.0046
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Onchocerca volvulus 0.0027 0.0008 0.0221
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0009 0.021
Onchocerca volvulus 0.0082 0.0049 0.1378
Onchocerca volvulus 0.0081 0.0048 0.1354
Echinococcus granulosus phd:f box containing protein 0.0042 0.002 0.002
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.4961 0.36 0.4845
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0004 0.0004
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Leishmania major cytochrome p450-like protein 0.0018 0.0002 0.0003
Schistosoma mansoni coup transcription factor 0.0167 0.011 0.011
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0016 0.0001 0.0003
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0082 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0002 0.0031
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.0014 0.0014
Onchocerca volvulus Serine\/threonine kinase homolog 0.0198 0.0133 0.3804
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Mycobacterium ulcerans monooxygenase 0.0027 0.0008 0.0186
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0002 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0167 0.011 0.011
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0128 0.0083 0.0111
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0009 0.0231
Loa Loa (eye worm) hypothetical protein 0.0169 0.0112 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Plasmodium falciparum topoisomerase I 1.3753 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0002 0.0033
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.002 0.0026
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0039 0.0052
Brugia malayi Calcitonin receptor-like protein seb-1 0.0164 0.0108 0.0108
Echinococcus granulosus neutral alpha glucosidase AB 0.0047 0.0023 0.0023
Brugia malayi hypothetical protein 0.0086 0.0052 0.0051
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0002 0.0043
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0048 0.0048
Brugia malayi nuclear hormone receptor family member odr-7 0.0079 0.0046 0.0046
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Trichomonas vaginalis inositol monophosphatase, putative 0.0016 0.0001 0.0005
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0001 0.0003
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Brugia malayi Cytochrome P450 family protein 0.0046 0.0022 0.0022
Trypanosoma brucei DNA topoisomerase III, putative 0.0255 0.0175 0.0235
Schistosoma mansoni nuclear receptor nhr-48 0.0079 0.0046 0.0046
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0129 0.0083 0.0083
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0001 0.0006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0014 0.0632
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0005 0.0103
Brugia malayi photoreceptor-specific nuclear receptor 0.1144 0.0822 0.0821
Entamoeba histolytica hypothetical protein 0.0223 0.0152 0.7374
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0079 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0066 0.0066
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0167 0.011 0.011
Mycobacterium ulcerans carveol-like dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium ulcerans DNA polymerase IV 0.0102 0.0064 0.1512
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0002 0.0043
Leishmania major hypothetical protein, conserved 0.0226 0.0154 0.0206
Echinococcus multilocularis caspase 0.0245 0.0167 0.0167
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0128 0.0082 0.1956
Brugia malayi intermediate filament protein 0.0082 0.0049 0.0048
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.0017 0.0002 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Trypanosoma brucei DNA topoisomerase ii 0.0056 0.003 0.004
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0001 0.0001
Schistosoma mansoni apoferritin-2 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0009 0.0009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Brugia malayi PXA domain containing protein 0.002 0.0004 0.0003
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0001 0.0001
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0009 0.0193
Echinococcus granulosus nibrin 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0004 0.0074
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0003 0.0054
Echinococcus multilocularis zinc finger protein 0.0022 0.0005 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.0014 0.0013
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0248 0.017 0.4225
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0002 0.0043
Echinococcus granulosus muscleblind protein 0.061 0.0433 0.0433
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0001
Leishmania major glycosyl hydrolase-like protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) DNA topoisomerase I 1.3753 1 1
Echinococcus granulosus kelch ECH associated protein 1 like 0.0097 0.006 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0167 0.011 0.011
Onchocerca volvulus 0.012 0.0076 0.217
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus granulosus somatostatin receptor 0.0027 0.0009 0.0009
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.0014 0.0013
Schistosoma mansoni cytochrome P450 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni zinc finger protein 0.0022 0.0005 0.0005
Echinococcus granulosus cathepsin l1 0.0023 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0088 0.0053 0.0053
Schistosoma mansoni glutaminase 0.0311 0.0215 0.0215
Echinococcus granulosus single minded 2 0.0186 0.0125 0.0125
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0008 0.0221
Loa Loa (eye worm) hypothetical protein 0.0127 0.0082 0.0082
Echinococcus granulosus FTZ F1 alpha 0.0167 0.011 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Brugia malayi PHD-finger family protein 0.0016 0.0001 0.0001
Brugia malayi nuclear hormone receptor family member nhr-6 0.0079 0.0046 0.0046
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0141
Loa Loa (eye worm) steroid hormone receptor 0.0167 0.011 0.011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0018 0.0018
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0004 0.0003
Echinococcus granulosus thyroid hormone receptor alpha 0.0079 0.0046 0.0046
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0167 0.011 0.011
Loa Loa (eye worm) RNA binding protein 0.0064 0.0036 0.0036
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0039 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0039 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0002 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.0083 0.0111
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0009 0.0009
Toxoplasma gondii hypothetical protein 0.0016 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0079
Brugia malayi Melatonin receptor type 1A 0.0027 0.0009 0.0008
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0006 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0167 0.011 0.011
Echinococcus granulosus sex peptide receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0022 0.0022
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0043 0.2072
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0103
Onchocerca volvulus Cell death protein 3 homolog 0.0179 0.0119 0.3399
Trypanosoma brucei glycosyl hydrolase-like protein 0.0017 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Brugia malayi Isocitrate dehydrogenase 0.0082 0.0049 0.0048
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.0014 0.0014
Trypanosoma cruzi metacaspase, putative 0.0093 0.0056 0.0075
Schistosoma mansoni cpg binding protein 0.0127 0.0081 0.0081
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0001 0.0001
Mycobacterium ulcerans ketoacyl reductase 0.0016 0.0001 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0043 0.0043
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0009 0.0009
Toxoplasma gondii DNA topoisomerase I, putative 1.3753 1 1
Treponema pallidum fructose-bisphosphate aldolase 0.0297 0.0205 1
Entamoeba histolytica DNA topoisomerase II, putative 0.0056 0.003 0.1437
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0009 0.0009
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0061 0.0061
Echinococcus multilocularis caspase 2 0.0179 0.0119 0.0119
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0016 0.0001 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0019 0.0019
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0066 0.0037 0.005
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0014 0.0371
Trypanosoma cruzi ABC transporter, putative 0.002 0.0004 0.0005
Brugia malayi bZIP transcription factor family protein 0.0087 0.0052 0.0052
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0079 0.0046 0.0046
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0033 0.0033
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0567 0.0402 0.0402
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0004 0.0004
Trypanosoma brucei Metacaspase-4 0.0093 0.0056 0.0075
Toxoplasma gondii LsmAD domain-containing protein 0.0155 0.0102 0.0102
Onchocerca volvulus 0.0016 0.0001 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Brugia malayi nuclear receptor NHR-88 0.0079 0.0046 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0027 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.0127 0.0082 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0061 0.0061
Schistosoma mansoni jumonji domain containing protein 0.0042 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus survival motor neuron protein 1 0.1466 0.1056 0.1056
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0017 0.0002 0.0055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.008 0.1899
Brugia malayi G-protein coupled receptor 0.0027 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0074 0.0043 0.0043
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0022 0.0022
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0251 0.0172 0.0172
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0002 0.0043
Leishmania major protein kinase, putative 0.0075 0.0043 0.0058
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0167 0.011 0.011
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0004 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis thyroid hormone receptor alpha 0.0167 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0041 0.0041
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0152 0.01 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0167 0.011 0.011
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0032 0.0042
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0008 0.0184
Loa Loa (eye worm) hypothetical protein 0.0034 0.0014 0.0014
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0001
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0011 0.001
Echinococcus multilocularis somatostatin receptor 0.0027 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0157 0.0104 0.0104
Brugia malayi glutaminase DH11.1 0.0311 0.0215 0.0215
Schistosoma mansoni myosin xvIII 0.0027 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0079 0.0046 0.0046
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0043 0.0043
Brugia malayi polk-prov protein 0.0051 0.0026 0.0026
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0167 0.011 0.011
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Echinococcus multilocularis protein tyrosine kinase 0.0247 0.0169 0.0169
Echinococcus multilocularis expressed conserved protein 0.0105 0.0066 0.0066
Schistosoma mansoni hypothetical protein 0.1039 0.0746 0.0746
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Onchocerca volvulus 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0048 0.0024 0.0024
Brugia malayi DIX domain containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0027 0.0009 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus kelch ECH associated protein 1 like 0.0097 0.006 0.006
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0009 0.0231
Echinococcus granulosus expressed protein 0.0026 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0023 0.0006 0.0007
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0005 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0016 0.0389
Schistosoma mansoni ferritin 0.0026 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0027 0.0009 0.0193
Plasmodium vivax SET domain containing protein 0.002 0.0003 0.0003
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0016 0.0021
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0587 0.0417 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0017 0.0001 0.0001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0018 0.0018
Entamoeba histolytica cysteine proteinase 2 0.0017 0.0002 0.0051
Leishmania major metacaspase, putative 0.0093 0.0056 0.0075
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0027 0.0009 0.0231
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Trichomonas vaginalis helicase, putative 0.0027 0.0009 0.021
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0009 0.0009
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0152 0.01 0.4838
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0017 0.0002 0.0033
Echinococcus granulosus apoptotic protease activating factor 1 0.0086 0.0052 0.0052
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0005 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0002 0.0051
Chlamydia trachomatis DNA gyrase subunit B 0.0056 0.003 0.1472
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Schistosoma mansoni nuclear receptor 0.0079 0.0046 0.0046
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0245 0.0167 0.0167
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0088 0.0053 0.0053
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0095 0.0059 0.0078
Trypanosoma brucei DNA polymerase IV, putative 0.0102 0.0064 0.0085
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0009 0.0231
Leishmania major hypothetical protein, conserved 0.0155 0.0102 0.0136
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Brugia malayi ABC transporter family protein 0.0017 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Mycobacterium leprae Possible regulatory protein 0.0065 0.0037 0.0865
Echinococcus multilocularis jumonji domain containing 1A 0.0042 0.002 0.002
Treponema pallidum DNA topoisomerase I (topA) 0.0291 0.0201 0.9764
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0017 0.0017
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0075 0.0043 0.0043
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.0023 0.0567
Echinococcus multilocularis survival motor neuron protein 1 0.1466 0.1056 0.1056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0167 0.011 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0071 0.1681
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Brugia malayi Melibiase family protein 0.0071 0.0041 0.004
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Plasmodium falciparum metacaspase-like protein 0.0093 0.0056 0.0056
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.00000010076 0.00000010076
Loa Loa (eye worm) RGS-3 protein 0.002 0.0004 0.0004
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0044 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0167 0.011 0.3142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0061 0.0061
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0023 0.003
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0009 0.0009
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0112 0.007 0.3412
Mycobacterium ulcerans oxidoreductase 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Leishmania major cathepsin L-like protease 0.0034 0.0014 0.0018
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0117 0.0074 0.01
Loa Loa (eye worm) hypothetical protein 0.0112 0.007 0.007
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0291 0.0201 1
Trichomonas vaginalis glucosylceramidase, putative 0.0567 0.0402 1
Schistosoma mansoni transcription factor LCR-F1 0.0223 0.0152 0.0152
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0011 0.0011
Brugia malayi cathepsin L-like precursor 0.0023 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0009 0.021
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0008 0.0177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0009 0.0008
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0052 0.0052
Echinococcus granulosus lysosomal alpha glucosidase 0.0153 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0222
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0009 0.0009
Schistosoma mansoni alpha-glucosidase 0.0124 0.0079 0.0079
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0024 0.0581
Echinococcus granulosus lamin 0.0082 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.007 0.007
Trypanosoma brucei membrane transporter protein, putative 0.007 0.004 0.0053
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0016 0.0001 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0167 0.011 0.011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0043 0.1063
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0014 0.0328
Loa Loa (eye worm) hypothetical protein 0.0179 0.0119 0.0119
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0039 0.1879
Schistosoma mansoni DNA polymerase eta 0.0127 0.0082 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.0048 0.0065
Schistosoma mansoni neuropeptide receptor 0.0027 0.0009 0.0009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0165 0.0109 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.004 0.0053
Schistosoma mansoni cpg binding protein 0.0127 0.0081 0.0081
Schistosoma mansoni neuropeptide receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0093 0.0056 0.0056
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0127 0.0082 0.0082
Trichomonas vaginalis sucrase-isomaltase, putative 0.0047 0.0023 0.0567
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0037 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0173
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0009 0.0008
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0065 0.0037 0.1799
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0005
Onchocerca volvulus 0.0021 0.0005 0.0113
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Echinococcus multilocularis lysosomal alpha glucosidase 0.0153 0.0101 0.0101
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0009 0.0009
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0004 0.0003
Echinococcus multilocularis kelch ECH associated protein 1 0.0097 0.006 0.006
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0039 0.0052
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0009 0.0231
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0006 0.0006
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0065 0.0037 0.0902
Loa Loa (eye worm) ABC transporter 0.0017 0.0002 0.0002
Loa Loa (eye worm) inositol-1 0.0152 0.01 0.01
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0021 0.0021
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0178 0.0118 0.0118
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0167 0.011 0.011
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0167 0.011 0.011
Brugia malayi Niemann-Pick C1 protein precursor 0.0112 0.007 0.007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0167 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.004 0.0018 0.0018
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.4961 0.36 0.4845
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0001 0.0001
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0032 0.0012 0.0012
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0017 0.0017
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Brugia malayi DKFZp564C0469 protein 0.0021 0.0005 0.0004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0002
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0003
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0006 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0008 0.0177
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0001 0.0001
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0167 0.011 0.011
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0248 0.017 0.407
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0017 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0093 0.0056 0.0056
Loa Loa (eye worm) cysteine protease 0.0034 0.0014 0.0014
Schistosoma mansoni ABC transporter 0.0017 0.0002 0.0002
Brugia malayi follicle stimulating hormone receptor 0.0251 0.0172 0.0171
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0014 0.0014
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0056 0.003 0.003
Plasmodium falciparum flap endonuclease 1 0.0026 0.0008 0.0008
Brugia malayi PXA domain containing protein 0.002 0.0004 0.0003
Mycobacterium ulcerans oxidoreductase 0.0016 0.0001 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0004 0.0074
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0022 0.0523
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0014 0.0014
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Echinococcus multilocularis aryl hydrocarbon receptor 0.0065 0.0037 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0016 0.0021
Echinococcus granulosus g protein coupled receptor 0.0027 0.0009 0.0009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0164 0.0108 0.0108
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Onchocerca volvulus 0.0086 0.0052 0.1467
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus granulosus caspase 3 0.0152 0.01 0.01
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0136 0.0088 0.2103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0178 0.0118 0.2938
Loa Loa (eye worm) jmjC domain-containing protein 0.0165 0.0109 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0002 0.0002
Loa Loa (eye worm) TOPoisomerase family member 0.0056 0.003 0.003
Giardia lamblia ABC transporter 0.002 0.0004 0.0148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus Protein ultraspiracle homolog 0.0167 0.011 0.3142
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0002 0.0043
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0043 0.0057
Schistosoma mansoni Smad4 0.0042 0.002 0.002
Echinococcus granulosus tumor protein p63 0.0351 0.0244 0.0244
Brugia malayi hypothetical protein 0.0155 0.0102 0.0101
Onchocerca volvulus 0.0016 0.0001 0.0004
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0056 0.003 0.004
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0023 0.0006 0.0242
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0008 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0011 0.0266
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0009 0.0009
Echinococcus multilocularis Kelch repeat type 1 0.0098 0.006 0.006
Schistosoma mansoni amine GPCR 0.0027 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0248 0.017 0.4225
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0016 0.0001 0.0008
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0052 0.0027 0.0026
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0032 0.0012 0.0012
Onchocerca volvulus 0.0016 0.0001 0.0004
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Schistosoma mansoni RAR-like nuclear receptor 0.0167 0.011 0.011
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0008 0.0375
Echinococcus granulosus caspase 0.0245 0.0167 0.0167
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0009 0.0009
Brugia malayi ORL1-like opioid receptor 0.0027 0.0009 0.0008
Leishmania major importin beta-1 subunit, putative 0.0048 0.0024 0.0031
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0008 0.0184
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0082 0.0049 0.0048
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis lysine specific demethylase 6a 0.0042 0.002 0.002
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0021 0.0021
Schistosoma mansoni inositol monophosphatase 0.0152 0.01 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0375 0.0262 0.0262
Leishmania major adenylate cyclase-like protein 0.0027 0.0008 0.0011
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0001 0.0001
Brugia malayi Bromodomain containing protein 0.0022 0.0005 0.0004
Echinococcus multilocularis peregrin 0.0044 0.0021 0.0021
Schistosoma mansoni regulator of G protein signaling 0.002 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0005 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0056 0.1397
Trypanosoma brucei glucosidase, putative 0.0047 0.0023 0.0031
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0008 0.0184
Loa Loa (eye worm) nuclear factor I 0.0023 0.0006 0.0006
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.002 0.002
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0002 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Schistosoma mansoni myo inositol monophosphatase 0.0016 0.0001 0.0001
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0002 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0076 0.0076
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0018 0.0018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0014 0.0014
Onchocerca volvulus 0.0016 0.0001 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0027 0.0009 0.0231
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.0095 0.2262
Brugia malayi G protein-coupled receptor 0.0027 0.0009 0.0008
Onchocerca volvulus 0.0027 0.0009 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0014 0.0013
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0056 0.003 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0127 0.0082 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0016 0.0389
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0016 0.0001 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0002 0.0051
Echinococcus multilocularis expressed protein 0.0387 0.0271 0.0271
Onchocerca volvulus 0.0024 0.0007 0.0169
Trichomonas vaginalis maltase-glucoamylase, putative 0.0047 0.0023 0.0567
Giardia lamblia PHD finger protein 15 0.0029 0.0011 0.0482
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0023 0.1092
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0065 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis jun protein 0.0087 0.0052 0.0052
Brugia malayi bHLH-PAS transcription factor 0.0186 0.0125 0.0124
Schistosoma mansoni patched 1 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.019 0.0127 0.3045
Plasmodium vivax vivapain-3 0.0017 0.0002 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0167 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0037 0.0902
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0009 0.0392
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0372 0.026 0.7431
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.0083 0.0111
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0049 0.0025 0.0025
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0119 0.0076 0.1804
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0001 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0026
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0005 0.0004
Toxoplasma gondii cathepsin CPL 0.0034 0.0014 0.0014
Echinococcus multilocularis DNA topoisomerase 1 1.3753 1 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.008 0.1899
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Echinococcus granulosus protein tyrosine kinase 0.0247 0.0169 0.0169
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0009 0.0193
Plasmodium falciparum DNA topoisomerase 3, putative 0.0248 0.017 0.0169
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0219 0.0149 0.0149
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.004 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0167 0.011 0.011
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0141
Echinococcus granulosus geminin 0.1039 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0065 0.0037 0.0037
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.008 0.1899
Leishmania major protein kinase, putative 0.0066 0.0037 0.005
Mycobacterium tuberculosis Probable dehydrogenase 0.0016 0.0001 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Mycobacterium ulcerans short-chain dehydrogenase 0.0016 0.0001 0.0003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0112 0.5446
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0007
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0082 0.0049 0.1151
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.0208 0.0279
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0009 0.0009
Echinococcus granulosus zinc finger protein 0.0022 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0103
Loa Loa (eye worm) hypothetical protein 0.015 0.0098 0.0098
Brugia malayi Cell death protein 3 precursor 0.0179 0.0119 0.0119
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0004 0.0077
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0167 0.011 0.011
Entamoeba histolytica DNA topoisomerase III, putative 0.0129 0.0083 0.4036
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0226 0.0154 0.0206
Brugia malayi MH2 domain containing protein 0.0042 0.002 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0001 0.0006
Chlamydia trachomatis DNA ligase 0.0021 0.0005 0.0197
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0003 0.0003
Plasmodium vivax topoisomerase I, putative 1.3753 1 1
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0023 0.0023
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0002 0.0043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0001 0.0033
Trichomonas vaginalis DNA topoisomerase II, putative 0.0056 0.003 0.0739
Schistosoma mansoni retinoic acid receptor RXR 0.0167 0.011 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0392 0.0274 0.6827
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0009 0.0009
Toxoplasma gondii hypothetical protein 0.0048 0.0024 0.0024
Leishmania major mitochondrial DNA topoisomerase II 0.0056 0.003 0.004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0002 0.0003
Brugia malayi larval opioid receptor 0.0027 0.0009 0.0008
Loa Loa (eye worm) fibroinase 0.0034 0.0014 0.0014
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0039 0.0039
Onchocerca volvulus 0.0027 0.0009 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0005 0.0126
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0006 0.0006
Brugia malayi conserved hypotetical protein 0.0079 0.0046 0.0046
Schistosoma mansoni smad 0.0042 0.002 0.002
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0001 0.0006
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0004 0.0153
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0002 0.0002
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0009 0.0009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0009 0.0009
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0065 0.0037 0.0049
Onchocerca volvulus 0.0027 0.0009 0.0231
Giardia lamblia GTOR 0.0047 0.0023 0.1092
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0009 0.0193
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0009 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0002 0.0033
Loa Loa (eye worm) hypothetical protein 0.061 0.0433 0.0433
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0297 0.0205 0.5109
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0192
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.0027 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0002 0.0043
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0076 0.0044 0.0044
Mycobacterium ulcerans dehydrogenase 0.0016 0.0001 0.0003
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0002 0.0002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0071 0.1681
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0016 0.0001 0.0008
Plasmodium falciparum thioredoxin reductase 0.0049 0.0025 0.0024
Plasmodium vivax unspecified product 0.0017 0.0002 0.0001
Schistosoma mansoni cpg binding protein 0.012 0.0076 0.0076
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0002 0.0002
Plasmodium falciparum DNA topoisomerase 2 0.0056 0.003 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0009 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.0023 0.0567
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0018 0.0439
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Echinococcus granulosus aryl hydrocarbon receptor 0.0065 0.0037 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0001 0.0001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0088 0.0053 0.0053
Entamoeba histolytica deoxycytidyl transferase, putative 0.0075 0.0043 0.2087
Trypanosoma cruzi metacaspase 5, putative 0.0093 0.0056 0.0075
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0128 0.0082 0.011
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0065 0.0037 0.0902
Brugia malayi RE15519p 0.0027 0.0009 0.0008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0036 0.0036
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0036 0.0036
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0002 0.0043
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.0093 0.0124
Loa Loa (eye worm) globin family protein 0.0027 0.0008 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0079 0.0046 0.0046
Echinococcus granulosus neuropeptide receptor 0.0027 0.0009 0.0009
Onchocerca volvulus 0.0016 0.0001 0.0004
Brugia malayi hypothetical protein 0.0079 0.0046 0.0046
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0152 0.01 0.0134
Schistosoma mansoni topbp1 0.0021 0.0005 0.0005
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0007 0.0173
Echinococcus multilocularis caspase 3 0.0152 0.01 0.01
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus multilocularis dna polymerase eta 0.0127 0.0082 0.0082
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0029 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Plasmodium vivax glutathione reductase, putative 0.0049 0.0025 0.0024
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0002 0.0003
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0016 0.0001 0.0003
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0129 0.0083 0.0083
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Echinococcus multilocularis FTZ F1 alpha 0.0167 0.011 0.011
Onchocerca volvulus 0.0034 0.0014 0.0371
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0016 0.0001 0.0003
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0152 0.01 0.0134
Trichomonas vaginalis alpha-glucosidase, putative 0.0017 0.0002 0.0033
Loa Loa (eye worm) ctsf protein 0.0034 0.0014 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus granulosus lysine specific demethylase 5A 0.0165 0.0109 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0014 0.0328
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0036 0.0036
Brugia malayi neuropeptide F receptor 0.0027 0.0009 0.0008
Schistosoma mansoni bromodomain containing protein 0.0022 0.0005 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0061 0.0061
Schistosoma mansoni ap endonuclease 0.0018 0.0002 0.0002
Loa Loa (eye worm) TK/FAK protein kinase 0.025 0.0171 0.0171
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0005 0.0004
Entamoeba histolytica serine/threonine protein kinase, putative 0.0198 0.0133 0.6484
Brugia malayi ecdysteroid receptor 0.0167 0.011 0.011
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0027 0.0009 0.0231
Onchocerca volvulus Huntingtin homolog 0.0375 0.0262 0.7483
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0009 0.0009
Echinococcus granulosus kelch ECH associated protein 1 0.0097 0.006 0.006
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0066 0.0066
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0152 0.01 0.01
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0025 0.058
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0053 0.0053
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4226 0.3065 0.3065
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0006 0.0007
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0021 0.0005 0.0191
Leishmania major DNA polymerase kappa, putative 0.0023 0.0006 0.0007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0021 0.0027
Schistosoma mansoni axis inhibition protein axin 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0014 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0167 0.011 0.011
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0049 0.0049
Brugia malayi Dopamine receptor protein 2 0.0027 0.0009 0.0008
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0152 0.01 0.0134
Brugia malayi ecdysone receptor 0.0079 0.0046 0.0046
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0016 0.0001 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.0023 0.0567
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0001 0.0001
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0167 0.011 0.011
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Schistosoma mansoni tsg101-related 0.0049 0.0025 0.0025
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0004 0.0004
Trypanosoma cruzi metacaspase, putative 0.0093 0.0056 0.0075
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0042 0.002 0.0026
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0006 0.0119
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Onchocerca volvulus 0.0079 0.0046 0.1307
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0375 0.0262 0.0262
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0009 0.0009
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0001 0.0004
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0034 0.0014 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0061 0.0061
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0049 0.0025 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0128 0.0082 0.1956
Echinococcus multilocularis cpg binding protein 0.0127 0.0081 0.0081
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0032 0.0032
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0016 0.0001 0.0003
Schistosoma mansoni aryl hydrocarbon receptor 0.0251 0.0172 0.0172
Echinococcus granulosus Nuclear hormone receptor HR96 0.0079 0.0046 0.0046
Trypanosoma cruzi DNA topoisomerase III, putative 0.0129 0.0083 0.0111
Onchocerca volvulus 0.0016 0.0001 0.0004
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0016 0.0001 0.0003
Brugia malayi Muscleblind-like protein 0.061 0.0433 0.0432
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0011 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0052 0.0027 0.0027
Trypanosoma brucei metacaspase MCA3 0.0093 0.0056 0.0075
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0042 0.002 0.0026
Entamoeba histolytica cysteine protease, putative 0.0034 0.0014 0.0632
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0009 0.0193
Toxoplasma gondii exonuclease III APE 0.0018 0.0002 0.0002
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0001 0.0001
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0009 0.0009
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0075 0.0043 0.0043
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0016 0.0001 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni DNA topoisomerase type I 1.3753 1 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0101 0.0063 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0083 0.0111
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0009 0.0392
Onchocerca volvulus 0.0016 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0027 0.0027
Trypanosoma brucei metacaspase MCA2 0.0093 0.0056 0.0075
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0023 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0167 0.011 0.011
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0002 0.0051
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0009 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0036 0.0036
Giardia lamblia Reductase, putative 0.0016 0.0001 0.0006
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0169 0.0112 0.5446
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0042 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0009 0.0009
Schistosoma mansoni intermediate filament proteins 0.0082 0.0049 0.0049
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0009 0.0009
Trypanosoma brucei trypanothione reductase 0.0049 0.0025 0.0033
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0001 0.0001
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0006 0.0204
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0009 0.0009
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0008 0.0337
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0014 0.0018
Echinococcus multilocularis muscleblind protein 1 0.061 0.0433 0.0433
Schistosoma mansoni alpha glucosidase 0.0047 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0012 0.0284
Plasmodium vivax DNA gyrase subunit B, putative 0.0056 0.003 0.0029
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0024 0.0024
Chlamydia trachomatis DNA topoisomerase I 0.0291 0.0201 1
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0112 0.0071 0.0071
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0004 0.0003
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0002 0.0002
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0005 0.0192
Brugia malayi PHD-finger family protein 0.0022 0.0005 0.0004
Brugia malayi RNA, U transporter 1 0.0167 0.0111 0.011
Brugia malayi Nuclear hormone receptor-like 1 0.0088 0.0053 0.0053
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0082 0.0049 0.0049
Schistosoma mansoni ferritin light chain 0.0026 0.0008 0.0008
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0079 0.0046 0.0046
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0002 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0133 0.0133
Mycobacterium tuberculosis Probable reductase 0.0112 0.0071 0.1681
Brugia malayi Cytochrome P450 family protein 0.0038 0.0017 0.0016
Leishmania major DNA polymerase kappa, putative 0.0082 0.0048 0.0065
Trypanosoma cruzi cruzipain precursor, putative 0.0128 0.0083 0.0111
Schistosoma mansoni biogenic amine receptor 0.0027 0.0009 0.0009
Brugia malayi Latrophilin receptor protein 2 0.0052 0.0027 0.0026
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0027 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0167 0.011 0.011
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0009 0.0392
Toxoplasma gondii histone lysine methyltransferase SET1 0.0244 0.0167 0.0167
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0017 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0061 0.1502
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0093 0.0056 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0009 0.021
Onchocerca volvulus 0.0023 0.0005 0.0139
Schistosoma mansoni multidrug resistance protein 0.007 0.004 0.004
Loa Loa (eye worm) nuclear hormone receptor 0.0079 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0009 0.0009
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0039 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0009 0.0009
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0009 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0223 0.0152 0.0152
Schistosoma mansoni caspase-7 (C14 family) 0.0245 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0024 0.0588
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0001
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0043 0.2072
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.0392 0.0274 0.6827
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0102 0.0136
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0001 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0297 0.0205 1
Schistosoma mansoni amine GPCR 0.0027 0.0009 0.0009
Echinococcus multilocularis ecdysone induced protein 78C 0.0167 0.011 0.011
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0039 0.0052
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0164 0.0108 0.0108
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.03 0.0208 0.0279
Trichomonas vaginalis glucosylceramidase, putative 0.0372 0.026 0.6464
Trypanosoma brucei DNA topoisomerase IA, putative 0.0248 0.017 0.0228
Loa Loa (eye worm) hypothetical protein 0.0051 0.0026 0.0026
Trypanosoma brucei unspecified product 0.0051 0.0027 0.0035
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0036 0.0036
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.1144 0.0822 0.0822
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0082 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0017 0.0017
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0002 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0009 0.021
Giardia lamblia DNA topoisomerase II 0.0056 0.003 0.1437
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.0133 0.3315
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0036 0.0036
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0001 0.0004
Brugia malayi hypothetical protein 0.0021 0.0005 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0047 0.0023 0.1101
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0016 0.0001 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0024 0.0581
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Echinococcus multilocularis tumor protein p63 0.0351 0.0244 0.0244
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.002 0.002
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0021 0.0972
Echinococcus granulosus cpg binding protein 0.0127 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0056 0.003 0.0843
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Brugia malayi orphan nuclear receptor NR2E1 0.0079 0.0046 0.0046
Schistosoma mansoni ferritin light chain 0.0026 0.0008 0.0008
Trypanosoma brucei DNA topoisomerase IB, large subunit 1.0224 0.7431 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0009 0.0009
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0003 0.006
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.0223 0.0152 0.7374
Trichomonas vaginalis steroid dehydrogenase, putative 0.0016 0.0001 0.0008
Echinococcus granulosus caspase 2 0.0179 0.0119 0.0119
Echinococcus granulosus snurportin 1 0.0628 0.0446 0.0446
Brugia malayi TAR-binding protein 0.0064 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0009 0.0222
Mycobacterium ulcerans short chain dehydrogenase 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0167 0.011 0.011
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0056 0.003 0.0708
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0021 0.0027
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0009 0.0009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0628 0.0446 0.0446
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0002 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0064 0.0085
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0021 0.0021
Trypanosoma cruzi DNA topoisomerase III, putative 0.0255 0.0175 0.0235
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0167 0.011 0.011
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0009 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0155 0.0102 0.0101
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0001 0.0019
Schistosoma mansoni apoferritin-2 0.0026 0.0008 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0014 0.0014
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0102 0.0101
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0002 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0032 0.0042
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0065 0.0037 0.0902
Brugia malayi topoisomerase 0.0021 0.0005 0.0004
Brugia malayi GRF zinc finger family protein 0.0063 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0023 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0009 0.0009
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0172 0.0114 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0167 0.011 0.011
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium leprae putative cytochrome p450 0.0018 0.0002 0.0043
Echinococcus granulosus biogenic amine 5HT receptor 0.015 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0014 0.0328
Onchocerca volvulus 0.0034 0.0014 0.0371
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0016 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.0604 0.0429 0.0429
Echinococcus multilocularis GPCR, family 2 0.0052 0.0027 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0082 0.0049 0.0049
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0032 0.0012 0.0012
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0066 0.0037 0.005
Entamoeba histolytica cysteine protease, putative 0.0017 0.0002 0.0051
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0009 0.0009
Schistosoma mansoni protein phosphatase 2C 0.0042 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0041 0.0041
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0167 0.011 0.011
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0009 0.0193
Echinococcus granulosus importin subunit beta 1 0.0059 0.0032 0.0032
Brugia malayi Pre-SET motif family protein 0.0065 0.0036 0.0036
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0005 0.0005
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0027 0.0009 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0003
Trichomonas vaginalis ran, putative 0.0043 0.0021 0.0502
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0005 0.0005
Brugia malayi nuclear receptor NHR-67 0.0079 0.0046 0.0046
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0178 0.0118 0.2938
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0079 0.0046 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0167 0.011 0.011
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0034 0.0014 0.0018
Brugia malayi acetyltransferase, GNAT family protein 0.0604 0.0429 0.0428
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0001 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0002 0.0043
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Echinococcus granulosus DNA topoisomerase 1 1.3753 1 1
Echinococcus multilocularis conserved hypothetical protein 0.0716 0.051 0.051
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0032 0.0042
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0009 0.0009
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0017 0.0002 0.0033
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0009 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0027 0.0009 0.0008
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0008
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0009 0.0009
Brugia malayi Glycosyl hydrolases family 31 protein 0.0153 0.0101 0.01
Brugia malayi MH1 domain containing protein 0.0042 0.002 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0036 0.0036
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0009 0.0009
Giardia lamblia Kinase, PLK 0.0198 0.0133 0.6484
Echinococcus granulosus dnaJ subfamily B 0.1311 0.0944 0.0944
Schistosoma mansoni alpha-glucosidase 0.0124 0.0079 0.0079
Onchocerca volvulus 0.0027 0.0009 0.0231
Brugia malayi Probable DNA topoisomerase II 0.0056 0.003 0.003
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0026 0.0035
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0127 0.3045
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0093 0.0056 0.1397
Loa Loa (eye worm) hypothetical protein 0.0079 0.0046 0.0046
Onchocerca volvulus 0.0034 0.0014 0.0371

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = -17 % Antiinflammatory activity in D-adjuvant induced arthiritis in rat measured by the change in body weight ChEMBL. 1732553
Inhibition (functional) = 17 % Antiinflammatory activity against carrageenan induced rat paw edema (CPE), dosed orally ChEMBL. 1732553
Inhibition (functional) = 26 % Antiinflammatory activity against D-adjuvant arthiritis in injected rat paw at the dose of 50 mg/kg by oral administration ChEMBL. 1732553
Inhibition (functional) = 60 % Antiinflammatory activity against D-adjuvant arthiritis in uninjected rat paw at the dose of 50 mg/kg by oral administration ChEMBL. 1732553

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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