Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0023 | 0.01 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0226 | 0.2018 | 1 |
Chlamydia trachomatis | dihydrofolate reductase | 0.1068 | 1 | 0.5 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0041 | 0.0269 | 0.0305 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, beta subunit | 0.0216 | 0.1927 | 0.9472 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0059 | 0.0067 |
Brugia malayi | CXXC zinc finger family protein | 0.0035 | 0.0207 | 0.0207 |
Echinococcus multilocularis | transcription factor btf3 | 0.0042 | 0.0279 | 0.0279 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0207 | 0.0207 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0058 | 0.043 | 0.043 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.003 | 0.0167 | 0.0123 |
Brugia malayi | nuclear hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0016 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0226 | 0.2018 | 0.5655 | |
Schistosoma mansoni | hypothetical protein | 0.0494 | 0.4558 | 0.4558 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0494 | 0.4558 | 0.4558 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0019 | 0.0059 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.047 | 0.047 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.01 | 0.01 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.029 | 0.029 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.029 | 0.0067 |
Toxoplasma gondii | NAC domain-containing protein | 0.0042 | 0.0279 | 0.0315 |
Onchocerca volvulus | 0.0058 | 0.043 | 0.1198 | |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.005 | 0.0354 | 0.0354 |
Brugia malayi | hypothetical protein | 0.0185 | 0.1633 | 0.1633 |
Onchocerca volvulus | 0.006 | 0.0444 | 0.1237 | |
Loa Loa (eye worm) | ICD-1 protein | 0.0042 | 0.0279 | 0.0279 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0016 | 0.0035 | 0.0087 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0041 | 0.0269 | 0.0305 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0226 | 0.2018 | 0.2018 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.1068 | 1 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0538 | 0.061 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.007 | 0.0538 | 0.061 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.029 | 0.0067 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0226 | 0.2018 | 1 |
Trypanosoma brucei | pteridine reductase 1 | 0.0235 | 0.2102 | 0.238 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0008 | 0.0008 |
Onchocerca volvulus | 0.0035 | 0.0207 | 0.0571 | |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.01 | 0.01 |
Onchocerca volvulus | 0.0016 | 0.0035 | 0.0087 | |
Loa Loa (eye worm) | hypothetical protein | 0.0286 | 0.2584 | 0.2584 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0167 | 0.0189 |
Trypanosoma cruzi | membrane transporter protein, putative | 0.0041 | 0.0269 | 0.0305 |
Brugia malayi | hypothetical protein | 0.002 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.1158 | 0.5055 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0042 | 0.0279 | 0.0315 |
Echinococcus granulosus | tumor protein p63 | 0.0408 | 0.3744 | 0.3744 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | cpg binding protein | 0.0037 | 0.0226 | 0.0226 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.1068 | 1 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.1068 | 1 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0014 | 0.0008 | 0.0008 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0016 | 0.0035 | 0.0087 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.005 | 0.0354 | 0.0433 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0013 | 0.0004 | 0.0004 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.007 | 0.0538 | 0.1492 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.0538 | 0.061 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0013 | 0.0004 | 0.0004 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.029 | 0.0067 |
Leishmania major | oxidoreductase-like protein | 0.0013 | 0.0004 | 0.0004 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0167 | 0.0123 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0016 | 0.0035 | 0.0035 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0945 | 0.8829 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0226 | 0.2018 | 0.2018 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.1158 | 0.5055 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | cpg binding protein | 0.0037 | 0.0226 | 0.0226 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0059 | 0.0067 |
Brugia malayi | thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Brugia malayi | hypothetical protein | 0.0286 | 0.2584 | 0.2584 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0066 | 0.0501 | 0.0567 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0016 | 0.0035 | 0.0035 |
Leishmania major | cytochrome p450-like protein | 0.0023 | 0.01 | 0.0114 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0013 | 0.0004 | 0.0004 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0042 | 0.0279 | 0.025 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.1068 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0226 | 0.2018 | 1 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.1927 | 0.1927 |
Echinococcus multilocularis | multidrug and toxin extrusion protein 2 | 0.0041 | 0.0269 | 0.0269 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | dnaJ subfamily B | 0.0494 | 0.4558 | 0.4558 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0156 | 0.1359 | 0.1359 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0945 | 0.8829 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0945 | 0.8829 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Schistosoma mansoni | survival motor neuron protein | 0.0058 | 0.043 | 0.043 |
Echinococcus granulosus | dihydrofolate reductase | 0.1068 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0945 | 0.8829 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.006 | 0.0444 | 0.0444 |
Brugia malayi | beta-NAC-like protein | 0.0042 | 0.0279 | 0.0279 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.1158 | 0.5055 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0226 | 0.2018 | 0.2018 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0185 | 0.1633 | 0.1633 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0016 | 0.0035 | 0.0035 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0226 | 0.2018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.01 | 0.0114 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0226 | 0.2018 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.0538 | 0.061 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0945 | 0.8829 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0016 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0016 | 0.0035 | 0.0087 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0019 | 0.0059 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0042 | 0.0279 | 0.0315 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0035 | 0.0035 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0042 | 0.0279 | 0.025 |
Onchocerca volvulus | Hexosaminidase D homolog | 0.005 | 0.0354 | 0.0983 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0286 | 0.2584 | 0.2584 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0043 | 0.029 | 0.029 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0016 | 0.0035 | 0.0035 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.1927 | 0.9472 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0185 | 0.1633 | 0.1849 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0059 | 0.0067 |
Echinococcus multilocularis | beta hexosaminidase subunit alpha | 0.0135 | 0.1158 | 0.1158 |
Schistosoma mansoni | dihydrofolate reductase | 0.1068 | 1 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0074 | 0.0575 | 0.0575 |
Schistosoma mansoni | multidrug resistance protein | 0.0041 | 0.0269 | 0.0269 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0016 | 0.0035 | 0.0035 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0167 | 0.0189 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0226 | 0.2018 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0016 | 0.0035 | 0.0035 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0226 | 0.2018 | 1 |
Echinococcus multilocularis | Multi antimicrobial extrusion protein MatE | 0.0038 | 0.0235 | 0.0235 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0016 | 0.0035 | 0.0035 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.0167 | 0.0189 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.029 | 0.029 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0019 | 0.0059 | 0.0059 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0016 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0354 | 0.0354 |
Schistosoma mansoni | transcription factor btf3 | 0.0042 | 0.0279 | 0.0279 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | coup transcription factor | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | transcription factor btf3 | 0.0042 | 0.0279 | 0.0279 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1817 | 0.1817 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.029 | 0.029 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | cpg binding protein | 0.0037 | 0.0226 | 0.0226 |
Onchocerca volvulus | 0.0389 | 0.3566 | 1 | |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0013 | 0.0004 | 0.0004 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0226 | 0.2018 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.029 | 0.0067 |
Echinococcus multilocularis | beta hexosaminidase subunit beta | 0.0216 | 0.1927 | 0.1927 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.1927 | 0.1927 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.029 | 0.029 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0389 | 0.3566 | 0.3566 |
Brugia malayi | ecdysteroid receptor | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0016 | 0.0035 | 0.0035 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0945 | 0.8829 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | geminin | 0.0205 | 0.1817 | 0.1817 |
Trypanosoma brucei | MATE efflux family protein, putative | 0.0041 | 0.0269 | 0.0305 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.043 | 0.043 |
Echinococcus multilocularis | cpg binding protein | 0.0037 | 0.0226 | 0.0226 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Loa Loa (eye worm) | glycosyl hydrolase family 20 | 0.0216 | 0.1927 | 0.1927 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0013 | 0.0004 | 0.0004 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0167 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Leishmania major | pteridine reductase 1 | 0.0238 | 0.2131 | 0.2414 |
Schistosoma mansoni | thyroid hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0389 | 0.3566 | 0.3566 |
Brugia malayi | hypothetical protein | 0.003 | 0.0167 | 0.0167 |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.005 | 0.0354 | 0.0354 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0016 | 0.0035 | 0.0035 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0042 | 0.0279 | 0.0315 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.1068 | 1 | 1 |
Brugia malayi | Dihydrofolate reductase | 0.1068 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0067 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.01 | 0.01 |
Echinococcus granulosus | beta hexosaminidase subunit alpha | 0.0135 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1817 | 0.1817 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | FTZ F1 alpha | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Leishmania major | basic transcription factor 3a, putative | 0.0042 | 0.0279 | 0.0315 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0185 | 0.1633 | 0.7784 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0023 | 0.01 | 0.01 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0013 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0035 | 0.0207 | 0.0207 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0014 | 0.0008 | 0.0008 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0016 | 0.0035 | 0.0035 |
Echinococcus granulosus | multidrug and toxin extrusion protein 2 | 0.0041 | 0.0269 | 0.0269 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0016 | 0.0035 | 0.0035 |
Schistosoma mansoni | thyroid hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0016 | 0.0035 | 0.0035 |
Brugia malayi | steroid hormone receptor | 0.0016 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0013 | 0.0004 | 0.0004 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, alpha subunit | 0.0216 | 0.1927 | 0.9472 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0226 | 0.2018 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0023 | 0.01 | 0.0114 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.1927 | 0.9472 |
Brugia malayi | nuclear receptor NHR-88 | 0.0016 | 0.0035 | 0.0035 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.003 | 0.0167 | 0.0189 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0016 | 0.0035 | 0.0035 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0269 | 0.0305 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.0167 | 0.0189 |
Echinococcus multilocularis | geminin | 0.0205 | 0.1817 | 0.1817 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0286 | 0.2584 | 0.2584 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.007 | 0.0538 | 0.1492 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0019 | 0.0059 | 0.0067 |
Echinococcus multilocularis | tumor protein p63 | 0.0408 | 0.3744 | 0.3744 |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.0216 | 0.1927 | 0.1927 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0016 | 0.0035 | 0.0035 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0135 | 0.1158 | 0.5055 |
Brugia malayi | Isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.01 | 0.01 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0016 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | thymidylate synthase | 0.0389 | 0.3566 | 0.3566 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0167 | 0.0167 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0041 | 0.0269 | 0.0305 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0016 | 0.0035 | 0.0035 |
Trypanosoma brucei | cytochrome P450, putative | 0.0023 | 0.01 | 0.0114 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0016 | 0.0035 | 0.0035 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0013 | 0.0004 | 0.0004 |
Echinococcus granulosus | beta hexosaminidase subunit beta | 0.0216 | 0.1927 | 0.1927 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.0035 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0059 | 0.0059 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 410 uM | Inhibition of human placental HexA using pNPGlcNAc substrate | ChEMBL. | 25984755 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.