Detailed information for compound 210629

Basic information

Technical information
  • TDR Targets ID: 210629
  • Name: N,2-dihydroxy-N-[1-(2-phenyl-1-benzofuran-5-y l)ethyl]acetamide
  • MW: 311.332 | Formula: C18H17NO4
  • H donors: 2 H acceptors: 3 LogP: 2.54 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC(=O)N(C(c1ccc2c(c1)cc(o2)c1ccccc1)C)O
  • InChi: 1S/C18H17NO4/c1-12(19(22)18(21)11-20)14-7-8-16-15(9-14)10-17(23-16)13-5-3-2-4-6-13/h2-10,12,20,22H,11H2,1H3
  • InChiKey: RBIUAEKBDXUHDR-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • N,2-dihydroxy-N-[1-(2-phenylbenzofuran-5-yl)ethyl]acetamide
  • N,2-dihydroxy-N-[1-(2-phenyl-5-benzofuranyl)ethyl]acetamide
  • N,2-dihydroxy-N-[1-(2-phenyl-1-benzofuran-5-yl)ethyl]ethanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Arachidonate 5-lipoxygenase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus 0.003 0.0152 0.0386
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0139 0.1232 0.2017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0597 0.0764
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.009
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0062 0.0054
Schistosoma mansoni hypothetical protein 0.0073 0.0581 0.0631
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis conserved hypothetical protein 0.0037 0.022 0.0212
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0075 0.0597 0.2026
Echinococcus granulosus sodium leak channel non selective protein 0.0037 0.022 0.0212
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0387 0.0493
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.136 0.3505
Onchocerca volvulus 0.0026 0.0107 0.0194
Onchocerca volvulus 0.0066 0.0503 0.1883
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Echinococcus multilocularis thioredoxin glutathione reductase 0.0487 0.4718 0.4714
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0133 0.0217
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0256 0.2408 0.3945
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0659 0.1079
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0503 0.0496
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0547 0.054
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0046 0.0307 0.0502
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0037 0.022 0.0359
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0282 0.0307
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.062 0.0674
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0482
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0032 0.0166 0.0455
Loa Loa (eye worm) hypothetical protein 0.0452 0.4363 0.7769
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0015 0.001
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0062 0.01
Trypanosoma cruzi calmodulin, putative 0.0026 0.0107 0.0129
Schistosoma mansoni ryanodine receptor related 0.0037 0.022 0.0239
Echinococcus multilocularis dnaJ subfamily B 0.0434 0.4179 0.4174
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0239 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0261 0.0887
Echinococcus multilocularis neuropeptides capa receptor 0.0139 0.1232 0.1225
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.0364 0.0356
Echinococcus multilocularis g protein coupled receptor 0.0139 0.1232 0.1225
Echinococcus granulosus dro:myosuppressin receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0144 0.0256
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0075 0.0597 0.0977
Brugia malayi hypothetical protein 0.0017 0.002 0.0032
Schistosoma mansoni transient receptor potential channel 0.0037 0.022 0.0239
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0282 0.2669 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0139 0.1232 0.1225
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0659 0.137
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0196 0.0189
Brugia malayi GnHR receptor homolog 0.0139 0.1232 0.2017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.0109
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0074 0.0585 0.0577
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0137 0.1211 0.1316
Plasmodium vivax thioredoxin reductase, putative 0.0487 0.4718 1
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0087 0.0713 0.1511
Loa Loa (eye worm) serotonin transporter b 0.0256 0.2408 0.4287
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0046 0.0307 0.03
Schistosoma mansoni inositol monophosphatase 0.0039 0.0239 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0271 0.0295
Giardia lamblia Calmodulin 0.0026 0.0107 0.0273
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0075 0.0597 0.1061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.0054
Loa Loa (eye worm) hypothetical protein 0.0031 0.0157 0.0277
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0177 0.0169
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0037 0.022 0.0359
Schistosoma mansoni sodium/chloride dependent transporter 0.0256 0.2408 0.2617
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0062 0.01
Echinococcus granulosus insulin receptor 0.0052 0.0364 0.0356
Onchocerca volvulus 0.003 0.0144 0.0354
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0209 0.0341
Toxoplasma gondii transporter, cation channel family protein 0.0056 0.0407 0.0833
Toxoplasma gondii NADPH-glutathione reductase 0.0282 0.2669 0.5644
Schistosoma mansoni neuropeptide receptor 0.0139 0.1232 0.1338
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0239 0.0476
Onchocerca volvulus DNA topoisomerase 2 homolog 0.01 0.0848 0.3352
Leishmania major calmodulin, putative 0.0026 0.0107 0.0129
Brugia malayi Cytochrome P450 family protein 0.0021 0.0053 0.0086
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0198 0.0369
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0271 0.0295
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Brugia malayi Heterochromatin protein 1 0.0074 0.0586 0.0958
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0597 0.1237
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus granulosus RUN 0.0066 0.0503 0.0496
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.01
Echinococcus granulosus transient receptor potential gamma protein 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0251 0.2352 0.4187
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0282 0.0275
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0659 0.1615
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0293 0.0993
Trypanosoma brucei NADH dehydrogenase 0.0075 0.0597 0.0764
Echinococcus granulosus glutamate NMDA receptor subunit 0.0347 0.3316 0.3311
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0095 0.0114
Brugia malayi Thioredoxin reductase 0.0487 0.4718 0.773
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0282 0.2669 0.2664
Chlamydia trachomatis endonuclease IV 0.0081 0.0659 0.2191
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0324 0.0575
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni chromobox protein 0.0074 0.0586 0.0636
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Brugia malayi Cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0443
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0062 0.0067
Brugia malayi G protein-coupled receptor 0.0139 0.1232 0.2017
Trypanosoma cruzi extracellular receptor, putative 0.0024 0.0089 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.0212
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis serotonin transporter 0.0256 0.2408 0.2402
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0075 0.0597 0.1265
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.2352 0.2346
Trypanosoma cruzi trypanothione reductase, putative 0.0487 0.4718 0.6108
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Mycobacterium ulcerans ferredoxin reductase 0.0075 0.0597 0.2144
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0166 0.0275
Schistosoma mansoni hypothetical protein 0.0051 0.0359 0.039
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0139 0.1232 0.2192
Echinococcus multilocularis receptor type guanylyl cyclase 0.003 0.0144 0.0137
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Loa Loa (eye worm) voltage-gated calcium channel 0.0037 0.022 0.039
Brugia malayi Inositol-1 0.0039 0.0239 0.039
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0282 0.0727
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0171 0.0163
Echinococcus multilocularis g protein coupled receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0053 0.0377 0.067
Entamoeba histolytica hypothetical protein 0.0025 0.0095 0.0222
Schistosoma mansoni lipoxygenase 0.0208 0.1924 0.2091
Brugia malayi Blistered cuticle protein 3 0.0077 0.0617 0.101
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0547 0.0699
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0139 0.1232 0.2017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0788 0.7718 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0137 0.1211 0.1205
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0229 0.2134 0.8833
Echinococcus granulosus alpha 1A adrenergic receptor 0.0139 0.1232 0.1225
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0053 0.0086
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0282 0.2669 0.3452
Echinococcus multilocularis adenylate cyclase 9 0.0083 0.0673 0.0666
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Echinococcus granulosus fmrfamide receptor 0.0139 0.1232 0.1225
Trichomonas vaginalis calmodulin, putative 0.0026 0.0107 0.0362
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0073 0.0581 0.0574
Onchocerca volvulus 0.0075 0.0597 0.2281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Echinococcus multilocularis neuropeptide receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) thioredoxin reductase 0.0487 0.4718 0.84
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0062 0.01
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0037 0.022 0.0359
Plasmodium falciparum glutathione reductase 0.0487 0.4718 1
Echinococcus granulosus dnaJ subfamily B 0.0434 0.4179 0.4174
Schistosoma mansoni neuropeptide receptor 0.0139 0.1232 0.1338
Giardia lamblia NADH oxidase lateral transfer candidate 0.0282 0.2669 0.9062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0129 0.0438
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0602 0.5864 0.7595
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0252 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0037 0.022 0.0275
Echinococcus multilocularis glutamate receptor 2 0.0122 0.1071 0.1064
Toxoplasma gondii selenide, water dikinase 0.0075 0.0597 0.1237
Loa Loa (eye worm) ion channel NompC 0.0037 0.022 0.039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0062 0.01
Leishmania major trypanothione reductase 0.0487 0.4718 0.6108
Brugia malayi hypothetical protein 0.0251 0.2352 0.3853
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0239 0.0424
Brugia malayi putative neuropeptide receptor NPR1 0.0139 0.1232 0.2017
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.1642 0.6736
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0487 0.4718 1
Schistosoma mansoni rab6-interacting 0.0066 0.0503 0.0547
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.1438 0.1432
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0031 0.0024
Onchocerca volvulus 0.0256 0.2408 1
Schistosoma mansoni glutamate synthase 0.0075 0.0597 0.0648
Schistosoma mansoni tyrosine kinase 0.0086 0.0708 0.0769
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0037 0.022 0.0359
Echinococcus granulosus shaker cognate 0.0037 0.022 0.0212
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0222 0.0215
Toxoplasma gondii endonuclease IV APN 0.0081 0.0659 0.137
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0376 0.0614
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0035 0.0198 0.042
Loa Loa (eye worm) hypothetical protein 0.0577 0.5616 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0282 0.2669 0.5644
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0075 0.0597 0.059
Echinococcus multilocularis transient receptor potential gamma protein 0.0037 0.022 0.0212
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0047 0.0158
Leishmania major mitochondrial DNA topoisomerase II 0.0166 0.1509 0.1947
Brugia malayi ORL1-like opioid receptor 0.0139 0.1232 0.2017
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0137 0.1211 0.1205
Trichomonas vaginalis glutamate synthase, putative 0.0075 0.0597 0.2026
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0255 0.0248
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0728 0.0721
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0586 0.1989
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0007
Brugia malayi glutathione reductase 0.0487 0.4718 0.773
Schistosoma mansoni tyrosine kinase 0.0084 0.0687 0.0747
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Trypanosoma brucei calmodulin 0.0026 0.0107 0.0129
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0018 0.0031 0.0031
Plasmodium falciparum glutathione reductase 0.0282 0.2669 0.5644
Schistosoma mansoni tyrosine kinase 0.0041 0.0255 0.0278
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.022 0.0435
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0139 0.1232 0.2017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0392 0.3765 1
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0015 0.0023
Brugia malayi neuropeptide F receptor 0.0139 0.1232 0.2017
Brugia malayi steroid hormone receptor 0.0021 0.0062 0.01
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0597 0.0764
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0047 0.004
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0086 0.0711 0.2293
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0047 0.004
Giardia lamblia Thioredoxin reductase 0.0075 0.0597 0.1952
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Brugia malayi hypothetical protein 0.0024 0.0089 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0677 0.6608 0.8559
Echinococcus multilocularis neuropeptide receptor 0.0139 0.1232 0.1225
Brugia malayi SRC-1 0.0041 0.0255 0.0417
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0037 0.022 0.0359
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0095 0.0171
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0089 0.0737 0.073
Echinococcus granulosus calmodulin 0.0026 0.0107 0.01
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0271 0.0264
Leishmania major hypothetical protein, conserved 0.0075 0.0597 0.0764
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.022 0.0212
Trypanosoma brucei C-8 sterol isomerase, putative 0.039 0.3747 0.4849
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0139 0.1232 0.1225
Chlamydia trachomatis thioredoxin reductase 0.0075 0.0597 0.1948
Loa Loa (eye worm) hypothetical protein 0.0066 0.0503 0.0895
Schistosoma mansoni voltage-dependent calcium channel 0.0037 0.022 0.0239
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0095 0.0167
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0211 0.0264
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.0054
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.0212
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0042 0.0271 0.0482
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0047 0.0068
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0007 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Loa Loa (eye worm) glutathione reductase 0.0487 0.4718 0.84
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0047 0.01
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0073 0.0581 0.0574
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Trypanosoma cruzi NADH dehydrogenase, putative 0.0075 0.0597 0.0764
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0198 0.042
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Mycobacterium tuberculosis Probable oxidoreductase 0.0392 0.3765 0.7981
Schistosoma mansoni calmodulin 0.0026 0.0107 0.0116
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0006 0.0017
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.0387 0.038
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Loa Loa (eye worm) hypothetical protein 0.0032 0.0172 0.0305
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.1112 0.1979
Echinococcus multilocularis sodium leak channel non selective protein 0.0037 0.022 0.0212
Schistosoma mansoni survival motor neuron protein 0.0051 0.0359 0.039
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0073 0.0581 0.0574
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Echinococcus granulosus voltage gated hydrogen channel 1 0.0037 0.022 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.01
Echinococcus multilocularis g protein coupled receptor 0.0139 0.1232 0.1225
Brugia malayi CXXC zinc finger family protein 0.003 0.0152 0.0248
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0157 0.0149
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.022 0.0359
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0139 0.1232 0.1225
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0021 0.007
Schistosoma mansoni hypothetical protein 0.0036 0.0209 0.0227
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0677 0.6608 0.8559
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0062 0.0067
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0042 0.0271 0.0264
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0075 0.0597 0.2144
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0089 0.0737 0.073
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0126
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0062 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.0212
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.0212
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0042 0.0271 0.0295
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0075 0.0597 0.059
Chlamydia trachomatis DNA gyrase subunit B 0.0086 0.0711 0.2391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0185
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0075 0.0597 0.0977
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0017
Schistosoma mansoni lipoxygenase 0.0326 0.3104 0.3373
Echinococcus granulosus lipoxygenase domain containing protein 0.0066 0.0503 0.0496
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0139 0.1232 0.1338
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0139 0.1232 0.1338
Leishmania major hypothetical protein, conserved 0.0027 0.0115 0.0139
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0261
Leishmania major hypothetical protein, conserved 0.0036 0.0211 0.0264
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0359 0.0586
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0018 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0139 0.1232 0.1225
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0089 0.0097
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0097 0.0813 0.1045
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Schistosoma mansoni biogenic amine receptor 0.0139 0.1232 0.1338
Leishmania major extracellular receptor, putative 0.0024 0.0089 0.0106
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0547 0.0699
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.004 0.0248 0.0696
Loa Loa (eye worm) hypothetical protein 0.0225 0.2099 0.3737
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0061
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0062 0.0054
Loa Loa (eye worm) hypothetical protein 0.039 0.3747 0.6671
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0196 0.0189
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0053 0.0093
Plasmodium vivax ABC transporter G family member 2, putative 0.0018 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0133 0.0236
Mycobacterium tuberculosis Probable dehydrogenase 0.0185 0.1693 0.3588
Brugia malayi Serotonin receptor 0.0626 0.6103 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0144 0.0256
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0095 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0372 0.0404
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0326 0.3104 0.3099
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0031 0.0024
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.022 0.0239
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.001
Mycobacterium ulcerans hypothetical protein 0.0021 0.0061 0.0115
Onchocerca volvulus 0.0044 0.0291 0.098
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.0387 0.0493
Echinococcus multilocularis GPCR, family 2 0.0017 0.0015 0.0007
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0139 0.1232 0.1225
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.022 0.0675
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0062 0.0467 0.1654
Schistosoma mansoni neuropeptide f receptor 76f 0.0139 0.1232 0.1338
Leishmania major calmodulin, putative 0.0026 0.0107 0.0129
Toxoplasma gondii thioredoxin reductase 0.0487 0.4718 1
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.0109
Onchocerca volvulus 0.0139 0.1232 0.4988
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0075 0.0597 0.1237
Loa Loa (eye worm) glutamate receptor 0.0024 0.0089 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0602 0.5864 0.7595
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0307 0.0334
Brugia malayi Glutamate receptor 2 precursor 0.0172 0.1563 0.2559
Brugia malayi cation channel family protein 0.0037 0.022 0.0359
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0255 0.0248
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0024 0.0089 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0677 0.6608 0.8559
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0073 0.0581 0.0574
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.0109
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0436 0.0894
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0492 0.4762 0.4758
Schistosoma mansoni tyrosine kinase 0.0159 0.1438 0.1563
Treponema pallidum thioredoxin reductase (trxB) 0.0075 0.0597 0.1898
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0271 0.092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0547 0.0895
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0047 0.0051
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0075 0.0597 0.1237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0157 0.0531
Echinococcus multilocularis orexin receptor type 2 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0083 0.0673 0.2606
Trichomonas vaginalis DNA topoisomerase II, putative 0.0148 0.1328 0.4512
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0139 0.1232 0.2192
Onchocerca volvulus 0.0029 0.0133 0.0307
Echinococcus granulosus hypothetical protein 0.0037 0.022 0.0212
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0095 0.0171
Echinococcus multilocularis jun protein 0.0089 0.0737 0.073
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0097 0.0813 0.1045
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0137 0.1211 0.1205
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0226 0.0768
Echinococcus granulosus neuropeptide receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Echinococcus granulosus Polycystic kidney disease protein 0.0066 0.0503 0.0496
Echinococcus granulosus metabotropic glutamate receptor 5 0.0024 0.0089 0.0082
Echinococcus multilocularis fmrfamide receptor 0.0139 0.1232 0.1225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0185 0.1693 0.3588
Trypanosoma cruzi calmodulin 0.0026 0.0107 0.0129
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0139 0.1232 0.4988
Leishmania major cytochrome p450-like protein 0.0021 0.0053 0.0059
Brugia malayi olfactory channel protein osm-9 0.0037 0.0222 0.0363
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0324 0.0529
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0062 0.0054
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Giardia lamblia GTOR 0.0048 0.0324 0.1016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0139 0.1232 0.1225
Trypanosoma brucei calmodulin 0.0026 0.0107 0.0129
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0062 0.0109
Echinococcus granulosus calmodulin 0.0026 0.0107 0.01
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0282 0.2669 0.3452
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.0387 0.0493
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus voltage gated potassium channel 0.0037 0.022 0.0212
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0196 0.1804 0.1798
Echinococcus granulosus biogenic amine 5HT receptor 0.0937 0.9203 0.9202
Echinococcus granulosus voltage dependent calcium channel 0.0137 0.1211 0.1205
Echinococcus granulosus g protein coupled receptor 0.0139 0.1232 0.1225
Plasmodium vivax amine transporter, putative 0.0044 0.0282 0.0568
Schistosoma mansoni ATP-binding cassette transporter 0.0172 0.1566 0.1702
Loa Loa (eye worm) hypothetical protein 0.0199 0.1841 0.3277
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0139 0.1232 0.1225
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0547 0.0699
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0095 0.0244
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.009
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.026 0.0253
Schistosoma mansoni tyrosine kinase 0.0086 0.0708 0.0769
Giardia lamblia Glutamate synthase 0.0075 0.0597 0.1952
Schistosoma mansoni hypothetical protein 0.0139 0.1232 0.1338
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0062 0.01
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0282 0.2669 0.5644
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0015 0.0025
Echinococcus multilocularis voltage gated potassium channel 0.0046 0.0307 0.03
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0037 0.022 0.0359
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1016 1 1
Echinococcus multilocularis transfer RNA-Gly 0.0037 0.022 0.0212
Schistosoma mansoni ap endonuclease 0.002 0.0047 0.0051
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.0387 0.0493
Echinococcus multilocularis glutamate receptor NMDA 0.0084 0.0683 0.0676
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0062 0.0067
Echinococcus multilocularis epidermal growth factor receptor 0.0086 0.0708 0.0701
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0095 0.0202
Echinococcus multilocularis glutamate synthase 0.0075 0.0597 0.059
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0062 0.0067
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0171 0.0331
Schistosoma mansoni 60S ribosomal protein L21 0.0041 0.0256 0.0278
Brugia malayi hypothetical protein 0.0066 0.0503 0.0823
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0075 0.0597 0.2096
Onchocerca volvulus 0.0032 0.0172 0.0472
Loa Loa (eye worm) TK protein kinase 0.0033 0.0177 0.0313
Onchocerca volvulus 0.0037 0.022 0.0675
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0324 0.0316
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0037 0.022 0.0239
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.0212
Echinococcus granulosus tyrosine kinase 0.0026 0.0109 0.0102
Schistosoma mansoni transient receptor potential channel 0.0037 0.022 0.0239
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0031 0.0024
Echinococcus multilocularis cpg binding protein 0.0032 0.0169 0.0162
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0274 0.2582 0.4231
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0282 0.0275
Brugia malayi ecdysteroid receptor 0.0021 0.0062 0.01
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0062 0.0067
Schistosoma mansoni protein kinase 0.003 0.0144 0.0157
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0274 0.2582 0.4598
Brugia malayi Dopamine receptor protein 2 0.0139 0.1232 0.2017
Schistosoma mansoni tyrosine kinase 0.0026 0.0109 0.0119
Loa Loa (eye worm) hypothetical protein 0.0041 0.0256 0.0455
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0074 0.0585 0.1039
Entamoeba histolytica disulphide oxidoreductase, putative 0.0075 0.0597 0.1943
Echinococcus granulosus epidermal growth factor receptor 0.0086 0.0708 0.0701
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0282 0.0568
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.022 0.0239
Plasmodium vivax calmodulin, putative 0.0026 0.0107 0.0196
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0075 0.0597 0.1265
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.01
Echinococcus granulosus neuropeptides capa receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) hypothetical protein 0.0056 0.0407 0.0723
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0075 0.0597 0.2096
Brugia malayi RE15519p 0.0139 0.1232 0.2017
Echinococcus granulosus receptor type guanylyl cyclase 0.003 0.0144 0.0137
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0075 0.0597 0.1446
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0255 0.0248
Brugia malayi larval opioid receptor 0.0139 0.1232 0.2017
Onchocerca volvulus 0.0139 0.1232 0.4988
Toxoplasma gondii hypothetical protein 0.0037 0.022 0.0435
Echinococcus multilocularis lamin 0.0029 0.0133 0.0126
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.0212
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0239 0.0732
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0062 0.0054
Trypanosoma brucei DNA topoisomerase II beta, putative 0.014 0.1248 0.1609
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.03
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0171 0.0163
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0687 0.6712 0.6709
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Loa Loa (eye worm) hypothetical protein 0.0032 0.0171 0.0302
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.0387 0.038
Echinococcus granulosus somatostatin receptor 0.0139 0.1232 0.1225
Trichomonas vaginalis glutathione reductase, putative 0.0282 0.2669 0.907
Echinococcus granulosus neuropeptide FF receptor 2 0.0139 0.1232 0.1225
Trypanosoma cruzi ABC transporter, putative 0.0018 0.0031 0.0031
Brugia malayi neuropeptide F receptor 0.0139 0.1232 0.2017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.0054
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0547 0.054
Schistosoma mansoni tyrosine kinase 0.0084 0.0687 0.0747
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0132 0.0448
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0387 0.1315
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0037 0.022 0.0359
Loa Loa (eye worm) hypothetical protein 0.0137 0.1211 0.2156
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0282 0.0275
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0324 0.041
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0075 0.0597 0.1446
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.0054
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0062 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0115 0.0212
Echinococcus granulosus ryanodine receptor 44f 0.0037 0.022 0.0213
Schistosoma mansoni neuropeptide receptor 0.0139 0.1232 0.1338
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0075 0.0597 0.0764
Echinococcus granulosus neuropeptide receptor A26 0.0626 0.6103 0.61
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0376 0.0668
Schistosoma mansoni jun-related protein 0.0072 0.057 0.062
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Schistosoma mansoni glutamate receptor NMDA 0.0279 0.2639 0.2868
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0067
Loa Loa (eye worm) hypothetical protein 0.0075 0.0597 0.1061
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0073 0.0085
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0239 0.0232
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0062 0.0067
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.062 0.0674
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0485 0.0863
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0282 0.0275
Onchocerca volvulus 0.0044 0.0282 0.0942
Echinococcus granulosus g protein coupled receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0222 0.0215
Brugia malayi Doublecortin family protein 0.0066 0.0503 0.0823
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0139 0.1232 0.1225
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0115 0.0212
Onchocerca volvulus 0.0066 0.0503 0.1883
Schistosoma mansoni histamine h1 receptor 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0053 0.0376 0.0668
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0282 0.0275
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0139 0.1232 0.2192
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0015 0.0008
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0075 0.0597 0.2026
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Plasmodium vivax multidomain scavenger receptor, putative 0.0066 0.0503 0.1038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Onchocerca volvulus Calmodulin homolog 0.0026 0.0107 0.0195
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0095 0.0171
Loa Loa (eye worm) hypothetical protein 0.0041 0.0261 0.0464
Loa Loa (eye worm) blistered cuticle protein 3 0.0077 0.0617 0.1098
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.0109
Trypanosoma cruzi NADH dehydrogenase, putative 0.0075 0.0597 0.0764
Echinococcus granulosus nmda type glutamate receptor 0.0197 0.1817 0.181
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0547 0.0699
Trypanosoma brucei calmodulin 0.0026 0.0107 0.0129
Plasmodium falciparum DNA gyrase subunit A 0.0032 0.0166 0.0321
Schistosoma mansoni neuropeptide F-like receptor 0.0139 0.1232 0.1338
Toxoplasma gondii hypothetical protein 0.0044 0.0282 0.0568
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0015 0.0023
Schistosoma mansoni amine GPCR 0.0139 0.1232 0.1338
Echinococcus granulosus voltage gated potassium channel 0.0046 0.0307 0.03
Echinococcus multilocularis neuropeptide FF receptor 2 0.0139 0.1232 0.1225
Schistosoma mansoni sulfide quinone reductase 0.0075 0.0597 0.0648
Loa Loa (eye worm) hypothetical protein 0.0256 0.2408 0.4287
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.004 0.0248 0.0696
Loa Loa (eye worm) G-protein coupled receptor 0.0139 0.1232 0.2192
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0728 0.0791
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.022 0.0212
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0075 0.0597 0.0764
Echinococcus granulosus neuropeptide receptor 0.0139 0.1232 0.1225
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0037 0.022 0.0275
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0152 0.0145
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0075 0.0597 0.059
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus multilocularis nmda type glutamate receptor 0.0108 0.0924 0.0918
Echinococcus granulosus jun protein 0.0089 0.0737 0.073
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Echinococcus granulosus nmda type glutamate receptor 0.0108 0.0924 0.0918
Onchocerca volvulus 0.0139 0.1232 0.4988
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Loa Loa (eye worm) TOPoisomerase family member 0.0148 0.1328 0.2363
Schistosoma mansoni ap endonuclease 0.002 0.0047 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0788 0.7718 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0062 0.0109
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1804 0.1798
Schistosoma mansoni myosin xvIII 0.0139 0.1232 0.1338
Treponema pallidum hypothetical protein 0.0025 0.0093 0.0161
Leishmania major ferric reductase, putative 0.0036 0.0209 0.0261
Onchocerca volvulus 0.007 0.0546 0.2066
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0255 0.0248
Brugia malayi Protein kinase domain containing protein 0.0052 0.0364 0.0595
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0324 0.041
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0074 0.0585 0.0956
Brugia malayi Metabotropic glutamate receptor precursor. 0.0024 0.0089 0.0145
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0042 0.0271 0.0264
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0062 0.0054
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0015 0.001
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.022 0.0675
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) solute carrier family 6 member 4 0.0256 0.2408 0.4287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0132 0.0448
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0239 0.0788
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0157 0.0277
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0086 0.0711 0.1507
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0324 0.041
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0157 0.0301
Brugia malayi hypothetical protein 0.007 0.0546 0.0894
Trypanosoma cruzi trypanothione reductase, putative 0.0282 0.2669 0.3452
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0032 0.0166 0.0321
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0222 0.0214
Echinococcus multilocularis conserved hypothetical protein 0.0731 0.7155 0.7153
Brugia malayi Transient-receptor-potential like protein 0.0037 0.022 0.0359
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0282 0.2669 0.3452
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Brugia malayi Serotonin receptor 0.0139 0.1232 0.2017
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0113 0.0981 0.0975
Brugia malayi hypothetical protein 0.0027 0.0115 0.0187
Echinococcus granulosus peptide allatostatin:somatostatin 0.0139 0.1232 0.1225
Trypanosoma brucei ATP-binding cassette protein, putative 0.0018 0.0031 0.0031
Echinococcus multilocularis G-protein coupled receptor, putative 0.0139 0.1232 0.1225
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0198 0.0634
Schistosoma mansoni amine GPCR 0.0139 0.1232 0.1338
Toxoplasma gondii exonuclease III APE 0.002 0.0047 0.0068
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.0212
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0053 0.0084
Loa Loa (eye worm) hypothetical protein 0.0577 0.5616 1
Schistosoma mansoni opsin-like receptor 0.0139 0.1232 0.1338
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Plasmodium vivax ferrodoxin reductase, putative 0.0075 0.0597 0.1237
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0859 0.0852
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.2058 0.3664
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0256 0.0278
Echinococcus granulosus tm gpcr rhodopsin 0.0687 0.6712 0.6709
Trypanosoma brucei DNA topoisomerase ii 0.0166 0.1509 0.1947
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0062 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0788 0.7718 1
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Toxoplasma gondii calmodulin, putative 0.0026 0.0107 0.0196
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0291 0.0317
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0115 0.0212
Onchocerca volvulus Alhambra homolog 0.0031 0.0157 0.0406
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0042 0.0271 0.0482
Brugia malayi PHD-finger family protein 0.0031 0.0157 0.0255
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0036 0.0211 0.0264
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0282 0.0275
Schistosoma mansoni inositol monophosphatase 0.0039 0.0239 0.026
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0075 0.0597 0.1237
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0277 0.027
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0035 0.0198 0.0634
Brugia malayi jmjC domain containing protein 0.0101 0.0859 0.1406
Brugia malayi Melatonin receptor type 1A 0.0139 0.1232 0.2017
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.0212
Brugia malayi chromobox protein homolog 3 0.0041 0.0261 0.0427
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0133 0.0236
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0139 0.1232 0.1225
Trichomonas vaginalis aldehyde oxidase, putative 0.0184 0.1683 0.5717
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Echinococcus multilocularis voltage dependent calcium channel 0.0137 0.1211 0.1205
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) TK/EGFR protein kinase 0.0159 0.1438 0.256
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Leishmania major hypothetical protein, conserved 0.0037 0.022 0.0275
Schistosoma mansoni DNA topoisomerase II 0.0148 0.1328 0.1443
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0036 0.0209 0.0261
Echinococcus multilocularis tumor protein p63 0.0358 0.3426 0.3421
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0597 0.0764
Onchocerca volvulus DNA topoisomerase 2 homolog 0.01 0.0848 0.3352
Echinococcus granulosus hypothetical protein 0.087 0.8539 0.8538
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0047 0.0066
Brugia malayi cation channel family protein 0.0037 0.022 0.0359
Mycobacterium tuberculosis Probable reductase 0.0185 0.1693 0.3588
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0255 0.0248
Plasmodium falciparum LCCL domain-containing protein 0.0066 0.0503 0.1038
Echinococcus multilocularis chromobox protein 1 0.0074 0.0586 0.0579
Brugia malayi Tachykinin-like peptides receptor 99D 0.0139 0.1232 0.2017
Schistosoma mansoni hypothetical protein 0.0066 0.0503 0.0547
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.0387 0.038
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.0212
Brugia malayi AKH receptor 0.0139 0.1232 0.2017
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0075 0.0597 0.1265
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) melatonin receptor type 1A 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0087 0.0713 0.2585
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0282 0.0275
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0047 0.0051
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0036 0.0039
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus granulosus two pore calcium channel protein 1 0.0037 0.022 0.0212
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0075 0.0597 0.1237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0023
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.0387 0.038
Brugia malayi MH2 domain containing protein 0.0127 0.1112 0.1821
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.01
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.014 0.1248 0.1609
Plasmodium vivax DNA gyrase subunit B, putative 0.0086 0.0711 0.148
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0451 0.4356 0.5639
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0677 0.6608 0.8559
Trichomonas vaginalis glutamate synthase, putative 0.0075 0.0597 0.2026
Plasmodium vivax glutathione reductase, putative 0.0487 0.4718 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0185
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0185 0.1693 0.4405
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0075 0.0597 0.0764
Brugia malayi hypothetical protein 0.0066 0.0503 0.0823
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0095 0.0244
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0062 0.0003
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0061 0.0115
Entamoeba histolytica calmodulin, putative 0.0026 0.0107 0.0262
Brugia malayi ion channel NompC 0.0037 0.022 0.0359
Brugia malayi Dopamine receptor 0.0139 0.1232 0.2017
Echinococcus multilocularis serotonin receptor 0.0397 0.3811 0.3806
Loa Loa (eye worm) hypothetical protein 0.0052 0.0372 0.066
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0047 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0108
Trypanosoma brucei calmodulin 0.0026 0.0107 0.0129
Chlamydia trachomatis DNA gyrase subunit B 0.0068 0.053 0.1687
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0261 0.0853
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0075 0.0597 0.059
Schistosoma mansoni sulfide quinone reductase 0.0075 0.0597 0.0648
Brugia malayi ABC transporter family protein 0.0016 0.0003 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0207 0.192 0.3145
Schistosoma mansoni tyrosine kinase 0.0084 0.0687 0.0747
Onchocerca volvulus 0.0139 0.1232 0.4988
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Echinococcus multilocularis sex peptide receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.0212
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0157 0.017
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0095 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0139 0.1232 0.1338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0104 0.0353
Plasmodium falciparum ferrodoxin reductase-like protein 0.0075 0.0597 0.1237
Mycobacterium ulcerans dehydrogenase 0.0075 0.0597 0.2144
Loa Loa (eye worm) heterochromatin protein 1 0.0074 0.0586 0.1041
Schistosoma mansoni amine GPCR 0.0139 0.1232 0.1338
Toxoplasma gondii hypothetical protein 0.0037 0.022 0.0435
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1739 0.5908
Schistosoma mansoni ABC transporter 0.0016 0.0003 0.0004
Echinococcus granulosus cpg binding protein 0.0032 0.0169 0.0162
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0075 0.0597 0.059
Brugia malayi ERG2 and Sigma1 receptor like protein 0.039 0.3747 0.6139
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Echinococcus multilocularis ATP binding cassette sub family G 0.0018 0.0031 0.0024
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0271 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0062 0.01
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0062 0.0054
Leishmania major DNA topoisomerase ii 0.014 0.1248 0.1609
Loa Loa (eye worm) TK protein kinase 0.0037 0.0217 0.0384
Echinococcus granulosus metabotropic glutamate receptor 2 0.0024 0.0089 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0115 0.0139
Giardia lamblia Fructose-bisphosphate aldolase 0.031 0.2943 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0062 0.0054
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0024 0.0089 0.0157
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0597 0.1237
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0061 0.013
Schistosoma mansoni hypothetical protein 0.0434 0.4179 0.4541
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.031 0.2943 1
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Echinococcus multilocularis tyrosine kinase 0.0026 0.0109 0.0102
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0282 0.0275
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0075 0.0597 0.059
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0282 0.2669 0.5658
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0075 0.0597 0.1446
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0239 0.081
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0392 0.3765 0.7981
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0042 0.0271 0.0264
Onchocerca volvulus 0.0139 0.1232 0.4988
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0086 0.0711 0.148
Schistosoma mansoni glutamate synthase 0.0075 0.0597 0.0648
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0075 0.0597 0.1265
Loa Loa (eye worm) norepinephrine transporter 0.0256 0.2408 0.4287
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0503 0.0496
Loa Loa (eye worm) hypothetical protein 0.0256 0.2408 0.4287
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Onchocerca volvulus 0.0139 0.1232 0.4988
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0062 0.0003
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0047 0.0051
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0568
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0239 0.081
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0075 0.0597 0.2026
Echinococcus granulosus sodium channel protein 0.0451 0.4356 0.4352
Echinococcus granulosus potassium large conductance calcium activated 0.0037 0.022 0.0212
Echinococcus granulosus G protein coupled receptor 139 0.0139 0.1232 0.1225
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.0387 0.1234
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0452 0.4363 0.7149
Echinococcus granulosus glutamate receptor 2 0.0196 0.1804 0.1798
Echinococcus granulosus allatostatin A receptor 0.0139 0.1232 0.1225
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Schistosoma mansoni glutamate synthase 0.0075 0.0597 0.0648
Echinococcus granulosus calcium activated potassium channel 0.0038 0.0225 0.0217
Trichomonas vaginalis set domain proteins, putative 0.0252 0.2363 0.8029
Schistosoma mansoni hypothetical protein 0.018 0.1642 0.1784
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0139 0.1232 0.1338
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0018 0.0031 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0047 0.0158
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0026 0.0107 0.01
Loa Loa (eye worm) hypothetical protein 0.006 0.045 0.08
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Echinococcus multilocularis shaker cognate 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0062 0.0067
Schistosoma mansoni lamin 0.0029 0.0133 0.0145
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0047 0.0076
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Schistosoma mansoni rab6-interacting 0.0066 0.0503 0.0547
Entamoeba histolytica hypothetical protein 0.0024 0.0089 0.02
Toxoplasma gondii hypothetical protein 0.0044 0.0282 0.0568
Giardia lamblia DNA topoisomerase II 0.014 0.1251 0.4196
Brugia malayi G-protein coupled receptor 0.0139 0.1232 0.2017
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0659 0.1398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Echinococcus multilocularis musashi 0.0029 0.0133 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Schistosoma mansoni neuropeptide F-like receptor 0.0139 0.1232 0.1338
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0075 0.0597 0.0977
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0008
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.0364 0.0356
Loa Loa (eye worm) glutamate receptor 2 0.0172 0.1563 0.2781
Trypanosoma cruzi DNA topoisomerase II, putative 0.014 0.1248 0.1609
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0287 0.0312
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0139 0.1232 0.1225
Echinococcus multilocularis dro:myosuppressin receptor 0.0139 0.1232 0.1225
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0042 0.0271 0.0295
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0024 0.0089 0.0157
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0115 0.0212
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Onchocerca volvulus 0.0079 0.0638 0.2457
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0239 0.081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0261 0.0887
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.01 0.0849 0.1511
Loa Loa (eye worm) doublecortin family protein 0.0066 0.0503 0.0895
Schistosoma mansoni alpha-1 adrenergic receptor 0.0139 0.1232 0.1338
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0062 0.0067
Treponema pallidum oxidoreductase 0.0075 0.0597 0.1898
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0547 0.0972
Echinococcus multilocularis allatostatin A receptor 0.0139 0.1232 0.1225
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0075 0.0597 0.2144
Schistosoma mansoni chromobox protein 0.0074 0.0586 0.0636
Onchocerca volvulus Neuropeptide F receptor homolog 0.0139 0.1232 0.4988
Schistosoma mansoni tyrosine kinase 0.0052 0.0364 0.0395
Loa Loa (eye worm) hypothetical protein 0.0081 0.0659 0.1173
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0659 0.137
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0075 0.0597 0.2144
Schistosoma mansoni microtubule-associated protein tau 0.0731 0.7155 0.7774
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0211 0.0264
Echinococcus granulosus serotonin receptor 0.0139 0.1232 0.1225
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0062 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0282 0.0275
Schistosoma mansoni hypothetical protein 0.0072 0.057 0.062
Plasmodium falciparum calmodulin 0.0026 0.0107 0.0196
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0282 0.2669 0.29
Treponema pallidum hypothetical protein 0.003 0.0146 0.0342
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0324 0.041
Leishmania major calmodulin, putative 0.0026 0.0107 0.0129
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0211 0.0417
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0075 0.0597 0.2026
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0602 0.5864 0.7595
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0324 0.1005
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Brugia malayi voltage-dependent calcium channel 0.0037 0.022 0.0359
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0282 0.0307
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0073 0.0581 0.0574
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0326 0.3104 0.3099
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0075 0.0597 0.2144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Onchocerca volvulus 0.0139 0.1232 0.4988
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0254 0.0862
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0062 0.0003
Schistosoma mansoni intermediate filament proteins 0.0029 0.0133 0.0145
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0075 0.0597 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0132 0.0448
Brugia malayi Adenylyl cyclase protein 0.0083 0.0673 0.1101
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0139 0.1232 0.1225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0226 0.0768
Schistosoma mansoni hypothetical protein 0.0139 0.1232 0.1338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0023
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0255 0.0248
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0282 0.2669 0.2664
Schistosoma mansoni neuropeptide receptor 0.0139 0.1232 0.1338
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0075 0.0597 0.059
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Loa Loa (eye worm) hypothetical protein 0.0083 0.0673 0.1197
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0597 0.0764
Echinococcus multilocularis potassium large conductance calcium activated 0.0037 0.022 0.0212
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.022 0.039
Brugia malayi MAP kinase sur-1 0.0054 0.0387 0.0633
Mycobacterium ulcerans endonuclease IV 0.0081 0.0659 0.2382
Brugia malayi metabotropic glutamate receptor type 2 0.0024 0.0089 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0139 0.1232 0.4988
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0087 0.0713 0.2585
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0211 0.0417
Plasmodium vivax DNA topoisomerase II, putative 0.0148 0.1328 0.2792
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0139 0.1232 0.1225
Brugia malayi isocitrate dehydrogenase 0.0017 0.0015 0.0023
Echinococcus granulosus glutamate receptor NMDA 0.0084 0.0683 0.0676
Leishmania major hypothetical protein, unknown function 0.0037 0.022 0.0275
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Brugia malayi Receptor family ligand binding region containing protein 0.003 0.0144 0.0235
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0347 0.3316 0.3311
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0141 0.0476
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0075 0.0597 0.1943
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0324 0.1005
Leishmania major hypothetical protein, conserved 0.0075 0.0597 0.0764
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0141 0.0476
Loa Loa (eye worm) hypothetical protein 0.0397 0.3811 0.6785
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0547 0.1772
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0062 0.0054
Onchocerca volvulus 0.0252 0.2365 0.9817
Schistosoma mansoni biogenic amine (5HT) receptor 0.0397 0.3811 0.4141
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0324 0.0316
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0282 0.0275
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0335 0.1135
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0226 0.0768
Schistosoma mansoni two-pore calcium channel 0.0037 0.022 0.0239
Echinococcus granulosus chromobox protein 1 0.0074 0.0586 0.0579
Chlamydia trachomatis DNA gyrase subunit A 0.0032 0.0166 0.0275
Brugia malayi Augmenter of liver regeneration 0.0036 0.0211 0.0345
Brugia malayi Guanylyl cyclase protein 23 0.003 0.0144 0.0235
Trypanosoma cruzi calmodulin, putative 0.0026 0.0107 0.0129
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0222 0.0215
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0239 0.026
Mycobacterium ulcerans glutamate synthase subunit beta 0.0075 0.0597 0.2144
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0728 0.1192
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0502
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0137 0.1211 0.1205
Plasmodium vivax SET domain protein, putative 0.0032 0.0171 0.0331
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0031 0.0024
Onchocerca volvulus 0.0139 0.1232 0.4988
Plasmodium falciparum ABC transporter G family member 2 0.0018 0.0031 0.0034
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.136 0.2882
Loa Loa (eye worm) hypothetical protein 0.0036 0.0209 0.037
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0036 0.0211 0.0204
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0075 0.0597 0.1446
Schistosoma mansoni voltage-gated ion channel 0.0037 0.022 0.0239
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0324 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0104 0.0353
Brugia malayi hypothetical protein 0.0037 0.022 0.0359
Schistosoma mansoni hypothetical protein 0.0139 0.1232 0.1338
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0062 0.01
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0023
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.022 0.0212
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0271 0.0264
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0139 0.1232 0.1338
Schistosoma mansoni opsin-like receptor 0.0139 0.1232 0.1338
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.03
Echinococcus granulosus calmodulin 0.0026 0.0107 0.01
Mycobacterium ulcerans NADH dehydrogenase 0.0075 0.0597 0.2144
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0053 0.0059
Echinococcus multilocularis geminin 0.018 0.1642 0.1636
Toxoplasma gondii Erv1 / Alr family protein 0.0036 0.0211 0.0417
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0139 0.1232 0.2192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.022 0.0359
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0282 0.0307
Schistosoma mansoni growth hormone secretagogue receptor 0.0139 0.1232 0.1338
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Plasmodium falciparum DNA topoisomerase 2 0.0148 0.1328 0.2792
Loa Loa (eye worm) adenylyl cyclase 3 0.0083 0.0673 0.1197
Trypanosoma cruzi C-8 sterol isomerase, putative 0.039 0.3747 0.4849
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0016
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0137 0.1211 0.1205
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0364 0.0646
Schistosoma mansoni hypothetical protein 0.0037 0.022 0.0239
Echinococcus multilocularis neuropeptide Y receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1804 0.1798
Trypanosoma cruzi calmodulin 0.0026 0.0107 0.0129
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0597 0.0764
Echinococcus granulosus glutamate synthase 0.0075 0.0597 0.059
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0042 0.0271 0.0264
Schistosoma mansoni opsin-like receptor 0.0139 0.1232 0.1338
Brugia malayi bZIP transcription factor family protein 0.0089 0.0737 0.1206
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni biogenic amine (5HT) receptor 0.0937 0.9203 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0227 0.0284
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0062 0.01
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0307 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0075 0.0597 0.059
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0075 0.0597 0.2026
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0037 0.022 0.0359
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0036 0.0211 0.0417
Treponema pallidum sodium- and chloride- dependent transporter 0.0256 0.2408 0.8154
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Leishmania major C-8 sterol isomerase-like protein 0.039 0.3747 0.4849
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0075 0.0597 0.059
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0282 0.0307
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0024 0.0089 0.0082
Trypanosoma brucei protein kinase, putative 0.0054 0.0387 0.0493
Plasmodium vivax DNA gyrase subunit A, putative 0.0032 0.0166 0.0321
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0217 0.0209
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0222 0.0215
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.031 0.2943 1
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0075 0.0597 0.059
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0148 0.1328 0.2175
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0015 0.0032
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.004 0.0248 0.0824
Echinococcus granulosus ATP binding cassette sub family G 0.0018 0.0031 0.0024
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0282 0.2669 0.5644
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0047 0.0082
Onchocerca volvulus 0.0088 0.0728 0.2842
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0282 0.2669 0.3452
Echinococcus granulosus tumor protein p63 0.0358 0.3426 0.3421
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0046 0.0049
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0018 0.0031 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0115 0.0139
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0324 0.0352
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0024 0.0089 0.0157
Leishmania major NADH dehydrogenase, putative 0.0075 0.0597 0.0764
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0037 0.022 0.0212
Onchocerca volvulus 0.0044 0.0282 0.0942
Loa Loa (eye worm) calcium channel 0.0137 0.1211 0.2156
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0061 0.0099
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Treponema pallidum NADH oxidase 0.0282 0.2669 0.9056
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0046 0.0307 0.03
Echinococcus granulosus peregrin 0.0031 0.0157 0.0149
Schistosoma mansoni polycystin 1-related 0.0066 0.0503 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0104 0.0353
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.001
Toxoplasma gondii DNA topoisomerase 2, putative 0.0148 0.1328 0.2792
Brugia malayi follicle stimulating hormone receptor 0.0139 0.1232 0.2017
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0021 0.007
Mycobacterium ulcerans hypothetical protein 0.0075 0.0597 0.2144
Schistosoma mansoni hypothetical protein 0.0075 0.0597 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Echinococcus granulosus intermediate filament protein 0.0029 0.0133 0.0126
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0207 0.192 0.3145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0105 0.0354
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0137 0.1211 0.1984
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.022 0.0212
Onchocerca volvulus 0.0051 0.0359 0.1267
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0137 0.1211 0.1316
Loa Loa (eye worm) hypothetical protein 0.0026 0.0109 0.0193
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0015 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Echinococcus granulosus g protein coupled receptor 0.0139 0.1232 0.1225
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.022 0.0212
Leishmania major hypothetical protein, conserved 0.0075 0.0597 0.0764
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0075 0.0597 0.1265
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0157 0.0149
Echinococcus granulosus 7TM GPCR rhodopsin 0.0139 0.1232 0.1225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0505 0.0548
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.03
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0075 0.0597 0.1943
Plasmodium falciparum thioredoxin reductase 0.0282 0.2669 0.5644
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0239 0.0232
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0166 0.1509 0.1947
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.01 0.0848 0.3352
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0859 0.0852
Brugia malayi Dopamine receptor protein 1 0.0577 0.5616 0.9202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0139 0.1232 0.1338
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0053 0.0093
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0032 0.0166 0.0352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0047 0.0051
Schistosoma mansoni voltage-gated cation channel 0.0137 0.1211 0.1316
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0282 0.0275
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0015 0.0016
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0075 0.0597 0.1943
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.004 0.0248 0.0527
Echinococcus multilocularis hyperpolarization activated cyclic 0.0042 0.0271 0.0264
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0075 0.0597 0.0764
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1804 0.1798
Brugia malayi G protein-coupled receptor F59B2.13 0.0139 0.1232 0.2017
Schistosoma mansoni vesicular amine transporter 0.0037 0.022 0.0239
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0282 0.2669 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0226 0.0768
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.022 0.0212
Loa Loa (eye worm) TYRA-2 protein 0.0139 0.1232 0.2192
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0047 0.0061
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1804 0.1798
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.0387 0.0493
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.1563 0.1698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0167 0.0566
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0062 0.0109
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0036 0.0211 0.0264
Loa Loa (eye worm) hypothetical protein 0.0397 0.3811 0.6785
Echinococcus multilocularis sodium channel protein 0.0492 0.4762 0.4758
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0185 0.1693 0.3588
Loa Loa (eye worm) ABC transporter 0.0016 0.0003 0.0004
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0177 0.0169
Brugia malayi putative neuropeptide receptor 0.0139 0.1232 0.2017
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0196 0.1804 0.1798
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Echinococcus granulosus thioredoxin glutathione reductase 0.0487 0.4718 0.4714
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0129 0.0438
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0452 0.4363 0.4741
Trichomonas vaginalis apoptosis inducing factor, putative 0.0075 0.0597 0.2026
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0038 0.0126
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0602 0.5864 0.7595
Entamoeba histolytica protein kinase, putative 0.0033 0.0177 0.0501
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0171 0.0163
Echinococcus multilocularis ryanodine receptor 44f 0.0037 0.022 0.0213
Loa Loa (eye worm) hypothetical protein 0.0087 0.0713 0.1268
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0137 0.1211 0.1205
Loa Loa (eye worm) neuropeptide F receptor 0.0139 0.1232 0.2192
Plasmodium falciparum transporter, putative 0.0044 0.0282 0.0568
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.022 0.0435
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0255 0.0248
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0086 0.0711 0.2532
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.0212
Onchocerca volvulus 0.0021 0.0062 0.0003
Schistosoma mansoni biogenic amine receptor 0.0139 0.1232 0.1338
Brugia malayi sulfakinin receptor protein 0.0139 0.1232 0.2017
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0277 0.027
Schistosoma mansoni cpg binding protein 0.003 0.0152 0.0165
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.2352 0.2346
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0095 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1739 0.5908
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.0139 0.1232 0.1225
Plasmodium falciparum thioredoxin reductase 0.0487 0.4718 1
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.022 0.0435
Schistosoma mansoni tyrosine kinase 0.0052 0.0364 0.0395
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0547 0.0594
Schistosoma mansoni cpg binding protein 0.0032 0.0169 0.0184
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0024 0.0089 0.0082
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0037 0.022 0.0239
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0202 0.0397
Echinococcus granulosus rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus granulosus calmodulin 0.0026 0.0107 0.01
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0227 0.0284
Mycobacterium ulcerans DNA gyrase subunit B 0.0086 0.0711 0.2577
Entamoeba histolytica thioredoxin reductase, putative 0.0075 0.0597 0.1943
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0282 0.2669 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0139 0.1232 0.4988
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0152 0.0269
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Echinococcus granulosus neuropeptide Y receptor 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.01 0.0849 0.1511
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0462
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0217 0.0209
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Schistosoma mansoni amine GPCR 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.0189
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0255 0.0248
Trypanosoma brucei ABC transporter, putative 0.0018 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0293 0.0993
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0255 0.0248
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.022 0.039
Echinococcus multilocularis serotonin receptor 0.0397 0.3811 0.3806
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.0225 0.0217
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0062 0.01
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Loa Loa (eye worm) inositol-1 0.0039 0.0239 0.0424
Schistosoma mansoni disulfide oxidoreductase 0.0075 0.0597 0.0648
Echinococcus multilocularis Polycystic kidney disease protein 0.0066 0.0503 0.0496
Echinococcus granulosus tm gpcr rhodopsin 0.0139 0.1232 0.1225
Schistosoma mansoni adenoreceptor 0.0139 0.1232 0.1338
Echinococcus multilocularis g-protein coupled receptor 0.0139 0.1232 0.1225
Schistosoma mansoni glutamate receptor NMDA 0.0347 0.3316 0.3603
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0196 0.1804 0.1798
Onchocerca volvulus 0.0052 0.0372 0.1322
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0282 0.2669 0.5644
Echinococcus granulosus CalModulin family member cmd 1 0.0026 0.0107 0.01
Echinococcus multilocularis chromobox protein 1 0.0074 0.0586 0.0579
Mycobacterium ulcerans monoxygenase 0.0075 0.0597 0.2144
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0038 0.0232 0.0462
Echinococcus multilocularis lipoxygenase domain containing protein 0.0066 0.0503 0.0496
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0568
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.003 0.0144 0.0354
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.0387 0.0688
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0133 0.0236
Onchocerca volvulus 0.0024 0.0089 0.0119
Brugia malayi G-protein coupled receptor 0.0139 0.1232 0.2017
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0788 0.7718 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0089 0.0157
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus multilocularis fmrfamide receptor 0.0139 0.1232 0.1225
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0075 0.0597 0.0764
Toxoplasma gondii hypothetical protein 0.0019 0.0035 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0115 0.0203
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0282 0.2669 0.4373
Echinococcus multilocularis two pore calcium channel protein 2 0.0037 0.022 0.0212
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0007
Echinococcus multilocularis RUN 0.0066 0.0503 0.0496
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus multilocularis glutamate receptor 2 0.0196 0.1804 0.1798
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0037 0.022 0.0212
Loa Loa (eye worm) voltage-dependent calcium channel 0.0056 0.0407 0.0723
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0139 0.1232 0.1225
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0597 0.0764
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0074 0.0585 0.0577
Brugia malayi Probable DNA topoisomerase II 0.0148 0.1328 0.2175
Loa Loa (eye worm) G-protein coupled receptor 0.0139 0.1232 0.2192
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Echinococcus granulosus GPCR family 2 0.0017 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0452 0.4363 0.7769
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.2582 0.8776
Schistosoma mansoni loxhd1 0.0066 0.0503 0.0547
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0075 0.0597 0.0764
Loa Loa (eye worm) programmed cell death 8 0.0075 0.0597 0.1061
Brugia malayi Receptor family ligand binding region containing protein 0.0024 0.0089 0.0145
Loa Loa (eye worm) hypothetical protein 0.0577 0.5616 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.003 0.0144 0.0256
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1642 0.558
Echinococcus granulosus g-protein coupled receptor 0.0139 0.1232 0.1225
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0075 0.0597 0.1237
Onchocerca volvulus Dual oxidase homolog 0.0077 0.0617 0.2369
Echinococcus granulosus neuropeptide s receptor 0.0626 0.6103 0.61
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0122 0.1063 0.3913
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0007 0.0008
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0157 0.0301
Echinococcus granulosus lamin 0.0029 0.0133 0.0126
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0042 0.0271 0.0264
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0196 0.1804 0.1798
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0227 0.0284
Schistosoma mansoni lamin 0.0029 0.0133 0.0145
Schistosoma mansoni tyrosine kinase 0.0026 0.0109 0.0119
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0282 0.2669 0.5644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0462
Trypanosoma cruzi DNA topoisomerase II, putative 0.014 0.1248 0.1609
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0015 0.0008
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0075 0.0597 0.1237
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0062 0.01
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0139 0.1232 0.1225
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0148 0.1328 0.1321
Treponema pallidum fructose-bisphosphate aldolase 0.031 0.2943 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0139 0.1232 0.1338
Echinococcus granulosus tyrosine kinase 0.0037 0.0217 0.0209
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0376 0.0614
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0166 0.1509 0.1947
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0053 0.0093
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0024 0.0089 0.0145
Brugia malayi Furin-like cysteine rich region family protein 0.0159 0.1438 0.2356
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Mycobacterium ulcerans hypothetical protein 0.003 0.0146 0.0436
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0075 0.0597 0.1952
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0036 0.0211 0.0204
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1563 0.1698
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0282 0.0462
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0032 0.0166 0.0412
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0139 0.1232 0.2192
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0282 0.0568
Echinococcus multilocularis lamin dm0 0.0029 0.0133 0.0126
Echinococcus granulosus lamin dm0 0.0029 0.0133 0.0126
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0139 0.1232 0.1338
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0148 0.1328 0.2175
Schistosoma mansoni transient receptor potential channel 4 0.0037 0.022 0.0239
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0037 0.022 0.0359
Echinococcus granulosus 7tm_1 domain containing protein 0.0139 0.1232 0.1225
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0062 0.0467 0.1654
Brugia malayi Pre-SET motif family protein 0.0032 0.0171 0.0278
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0115 0.0139
Loa Loa (eye worm) neuropeptide F receptor 0.0139 0.1232 0.2192
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0255 0.0248
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.0387 0.0792
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0062 0.0067
Loa Loa (eye worm) hypothetical protein 0.0037 0.0222 0.0394
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0037 0.022 0.0212
Echinococcus granulosus serotonin transporter 0.0256 0.2408 0.2402
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0728 0.0721
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Schistosoma mansoni metabotropic glutamate receptor 0.0024 0.0089 0.0097
Echinococcus multilocularis nmda type glutamate receptor 0.0197 0.1817 0.181
Echinococcus granulosus microtubule associated protein 2 0.0731 0.7155 0.7153
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Schistosoma mansoni coup transcription factor 0.0021 0.0062 0.0067
Trypanosoma brucei trypanothione reductase 0.0487 0.4718 0.6108
Plasmodium falciparum DNA gyrase subunit B 0.0086 0.0711 0.148
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0282 0.2669 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0008
Brugia malayi intermediate filament protein 0.0029 0.0133 0.0217
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.022 0.0239
Echinococcus granulosus biogenic amine 5HT receptor 0.0397 0.3811 0.3806
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0037 0.022 0.0239
Echinococcus multilocularis NMDA receptor 0.0073 0.0581 0.0574
Trichomonas vaginalis mercuric reductase, putative 0.0282 0.2669 0.907
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0171 0.0185
Echinococcus granulosus orexin receptor type 2 0.0139 0.1232 0.1225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0226 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus multilocularis somatostatin receptor 0.0139 0.1232 0.1225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Schistosoma mansoni jumonji domain containing protein 0.008 0.0651 0.0708
Echinococcus multilocularis insulin receptor 0.0052 0.0364 0.0356
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1563 0.1698
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0075 0.0597 0.1943
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.0387 0.0493
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0217 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0387 0.0421
Echinococcus multilocularis voltage dependent calcium channel 0.0137 0.1211 0.1205
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0185 0.1693 0.3588
Schistosoma mansoni hypothetical protein 0.0139 0.1232 0.1338
Loa Loa (eye worm) hypothetical protein 0.0069 0.0533 0.0948
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0075 0.0597 0.0764
Echinococcus multilocularis neuropeptide s receptor 0.0626 0.6103 0.61
Echinococcus granulosus glutamate receptor subunit protein glur 0.0073 0.0581 0.0574
Echinococcus granulosus geminin 0.018 0.1642 0.1636
Brugia malayi nuclear hormone receptor 0.0021 0.0062 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Brugia malayi calmodulin 0.0026 0.0107 0.0174
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0282 0.0307
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0157 0.0301
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0217 0.0209
Echinococcus granulosus two pore calcium channel protein 2 0.0037 0.022 0.0212
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0018 0.0031 0.0031
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0239 0.03
Brugia malayi nuclear receptor NHR-88 0.0021 0.0062 0.01
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0252 0.0245
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0392 0.3765 0.7981
Echinococcus granulosus voltage dependent calcium channel 0.0056 0.0407 0.04
Loa Loa (eye worm) hypothetical protein 0.0044 0.0282 0.0502
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.022 0.0212
Echinococcus multilocularis 0.0049 0.0337 0.0329
Brugia malayi Cytochrome P450 family protein 0.0021 0.0053 0.0086
Echinococcus granulosus chromobox protein 1 0.0074 0.0586 0.0579
Treponema pallidum quinoline 2-oxidoreductase 0.0029 0.0139 0.0318
Onchocerca volvulus 0.0029 0.0133 0.0307
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0037 0.022 0.0359
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0086 0.0708 0.0701
Loa Loa (eye worm) hypothetical protein 0.0256 0.2408 0.4287
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Schistosoma mansoni hypothetical protein 0.018 0.1642 0.1784
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0075 0.0597 0.059
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.022 0.0212
Chlamydia trachomatis glutamine binding protein 0.004 0.0248 0.0594
Echinococcus granulosus adenylate cyclase 9 0.0083 0.0673 0.0666
Echinococcus granulosus glutamate receptor 2 0.0122 0.1071 0.1064
Schistosoma mansoni transient receptor potential channel 0.0037 0.0222 0.0241
Echinococcus multilocularis neuropeptide receptor A26 0.0626 0.6103 0.61
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0083 0.0673 0.2606
Brugia malayi protein-tyrosine kinase 0.0037 0.0217 0.0354
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0139 0.1232 0.2017
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0937 0.9203 0.9202
Echinococcus granulosus tachykinin peptides receptor 99D 0.0139 0.1232 0.1225
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis glutamate receptor 2 0.0172 0.1563 0.1556
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0075 0.0597 0.2144
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0075 0.0597 0.059
Echinococcus granulosus atrial natriuretic peptide receptor 0.0024 0.0089 0.0082
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0462
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0293 0.0986
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.022 0.0435
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.136 0.5036
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0095 0.0185
Echinococcus granulosus sex peptide receptor 0.0139 0.1232 0.1225
Trypanosoma cruzi calmodulin, putative 0.0026 0.0107 0.0129
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0062 0.0054
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0049 0.0335 0.1135
Loa Loa (eye worm) hypothetical protein 0.006 0.045 0.08
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0139 0.1232 0.1338
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0222 0.0215
Brugia malayi Glutamate receptor 1 precursor 0.0172 0.1563 0.2559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0007 0.0023
Echinococcus multilocularis neuropeptide Y receptor 0.0139 0.1232 0.1225
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0037 0.022 0.0212
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0239 0.0232
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0075 0.0597 0.2096
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0139 0.1232 0.1338
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0073 0.0581 0.0574
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0239 0.026
Loa Loa (eye worm) glutamate receptor 1 0.0172 0.1563 0.2781
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0184 0.1683 0.5717
Loa Loa (eye worm) hepatopoietin HPO2 0.0036 0.0211 0.0374
Loa Loa (eye worm) hypothetical protein 0.0028 0.0128 0.0227
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0075 0.0597 0.2144
Schistosoma mansoni cpg binding protein 0.0032 0.0169 0.0184
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0282 0.2669 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0324 0.1098
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0217 0.0209
Schistosoma mansoni glutamate receptor kainate 0.0172 0.1563 0.1698
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0047 0.0068
Echinococcus granulosus neuropeptide Y receptor 0.0139 0.1232 0.1225
Giardia lamblia PHD finger protein 15 0.0031 0.0157 0.0442
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0007 0.0011
Onchocerca volvulus 0.0139 0.1232 0.4988
Echinococcus granulosus hyperpolarization activated cyclic 0.0042 0.0271 0.0264
Schistosoma mansoni glutamate receptor AMPA 0.0172 0.1563 0.1698
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0042 0.0271 0.0264
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0256 0.2408 0.2617
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.0387 0.0493
Loa Loa (eye worm) hypothetical protein 0.0139 0.1232 0.2192
Brugia malayi hypothetical protein 0.0044 0.0282 0.0462
Schistosoma mansoni biogenic amine receptor 0.0139 0.1232 0.1338
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0037 0.022 0.0212
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0148 0.1328 0.1321
Brugia malayi jmjC domain containing protein 0.0039 0.0239 0.039
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0062 0.0067
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0075 0.0597 0.1237
Brugia malayi glutamate synthase 0.0075 0.0597 0.0977
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0015 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0062 0.0054
Brugia malayi Pre-SET motif family protein 0.0221 0.2058 0.3372
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0075 0.0597 0.1943
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0053 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0126
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0255 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0202 0.0684
Echinococcus multilocularis two pore calcium channel protein 1 0.0037 0.022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0046 0.0307 0.0545
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.1112 0.1979
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0062 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.031 0.2943 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0728 0.1295
Schistosoma mansoni hypothetical protein 0.0031 0.0157 0.017
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0282 0.2669 1
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0075 0.0597 0.1265
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0037 0.022 0.0212
Echinococcus multilocularis peregrin 0.0031 0.0157 0.0149
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0586 0.1989
Loa Loa (eye worm) hypothetical protein 0.0066 0.0503 0.0895
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0054 0.0392 0.1367
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0062 0.0109
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.004 0.0248 0.0594
Loa Loa (eye worm) SRC-1 0.0041 0.0255 0.0453
Onchocerca volvulus 0.0044 0.0282 0.0942
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0502
Echinococcus multilocularis G protein coupled receptor 139 0.0139 0.1232 0.1225
Schistosoma mansoni tyrosine kinase 0.0041 0.0255 0.0278
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0324 0.041
Loa Loa (eye worm) hypothetical protein 0.0021 0.0062 0.0109
Plasmodium falciparum phd finger protein, putative 0.0031 0.0157 0.0301
Brugia malayi hypothetical protein 0.0139 0.1232 0.2017
Echinococcus multilocularis calmodulin 0.0026 0.0107 0.01
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0282 0.0568
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0037 0.022 0.0212
Echinococcus granulosus neuropeptides capa receptor 0.0139 0.1232 0.1225
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0137 0.1211 0.1205
Echinococcus multilocularis microtubule associated protein 2 0.0731 0.7155 0.7153
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Schistosoma mansoni amine GPCR 0.0665 0.6493 0.7055
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0184 0.1683 0.5717
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0139 0.1232 0.1338
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0008
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.1438 0.1432
Brugia malayi Bromodomain containing protein 0.0031 0.0157 0.0255
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.022 0.0239
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0062 0.0467 0.0991
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0185 0.1693 0.3588
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0042 0.0271 0.092
Loa Loa (eye worm) ryanodine receptor 0.0037 0.022 0.039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0025
Entamoeba histolytica DNA topoisomerase II, putative 0.0148 0.1328 0.4454
Mycobacterium ulcerans DNA gyrase subunit A 0.0032 0.0166 0.0513
Mycobacterium ulcerans epimerase 0.0021 0.0061 0.0115
Loa Loa (eye worm) hypothetical protein 0.0037 0.022 0.039
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0075 0.0597 0.2144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0139 0.1232 0.1225

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 27.5 mg kg-1 In vivo inhibition of 5-lipoxygenase (LTC4) in the mouse zymosan peritonitis assay at an oral dose of 30 mg/Kg ChEMBL. 7932593
ED50 (functional) = 27.5 mg kg-1 In vivo inhibition of 5-lipoxygenase (LTC4) in the mouse zymosan peritonitis assay at an oral dose of 30 mg/Kg ChEMBL. 7932593
IC50 (binding) = 0.7 uM In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay ChEMBL. 7932593
IC50 (binding) = 0.7 uM In vitro inhibition of 5-lipoxygenase (5-HETE) derived from the 9000xg supernatant of RBL broken cell assay ChEMBL. 7932593

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.