Detailed information for compound 2108011

Basic information

Technical information
  • TDR Targets ID: 2108011
  • Name: 2-[3-[(1R)-1-[(2S)-1-[(2S)-2-cyclohexyl-2-phe nylacetyl]piperidine-2-carbonyl]oxy-3-(3,4-di methoxyphenyl)propyl]phenoxy]acetic acid
  • MW: 657.792 | Formula: C39H47NO8
  • H donors: 1 H acceptors: 4 LogP: 8.24 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(CC[C@H](c2cccc(c2)OCC(=O)O)OC(=O)[C@@H]2CCCCN2C(=O)[C@H](c2ccccc2)C2CCCCC2)ccc1OC
  • InChi: 1S/C39H47NO8/c1-45-34-22-20-27(24-35(34)46-2)19-21-33(30-16-11-17-31(25-30)47-26-36(41)42)48-39(44)32-18-9-10-23-40(32)38(43)37(28-12-5-3-6-13-28)29-14-7-4-8-15-29/h3,5-6,11-13,16-17,20,22,24-25,29,32-33,37H,4,7-10,14-15,18-19,21,23,26H2,1-2H3,(H,41,42)/t32-,33+,37+/m0/s1
  • InChiKey: POAFNNRQISTGEJ-QUBOUHRKSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[3-[(1R)-1-[(2S)-1-[(2S)-2-cyclohexyl-2-phenyl-acetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
  • 2-[3-[(1R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-1-oxo-2-phenylethyl]-2-piperidinyl]-oxomethoxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
  • 2-[3-[(1R)-1-[(2S)-1-[(2S)-2-cyclohexyl-2-phenyl-ethanoyl]piperidin-2-yl]carbonyloxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]ethanoic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens FK506 binding protein 1A, 12kDa Starlite/ChEMBL References
Homo sapiens FK506 binding protein 5 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 Get druggable targets OG5_126727 All targets in OG5_126727
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma brucei gambiense peptidylprolyl isomerase-like protein, putative Get druggable targets OG5_126727 All targets in OG5_126727
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Candida albicans one of two identical potential FKBP-type peptidyl-prolyl cis-trans isomerase genes Get druggable targets OG5_126727 All targets in OG5_126727
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Trichomonas vaginalis immunophilin, putative Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 Get druggable targets OG5_126727 All targets in OG5_126727
Candida albicans one of two identical potential FKBP-type peptidyl-prolyl cis-trans isomerase genes Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma congolense FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma mansoni immunophilin Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania major peptidylprolyl isomerase-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania infantum fk506-binding protein 1-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania mexicana peptidylprolyl isomerase-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus multilocularis fk506 binding protein Get druggable targets OG5_126727 All targets in OG5_126727
Loa Loa (eye worm) FKBP5 protein Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma mansoni immunophilin Get druggable targets OG5_126727 All targets in OG5_126727
Candida albicans one of two identical potential FKBP-type peptidyl-prolyl cis-trans isomerase genes Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania donovani peptidylprolyl isomerase-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_126727 All targets in OG5_126727
Neospora caninum Peptidylprolyl isomerase D (Cyclophilin D), related Get druggable targets OG5_126727 All targets in OG5_126727
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 Get druggable targets OG5_126727 All targets in OG5_126727
Trichomonas vaginalis peptidylprolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Trichomonas vaginalis fk506-binding protein, putative Get druggable targets OG5_126727 All targets in OG5_126727
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126727 All targets in OG5_126727
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma japonicum ko:K09568 FK506-binding protein 1, putative Get druggable targets OG5_126727 All targets in OG5_126727
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 Get druggable targets OG5_126727 All targets in OG5_126727
Plasmodium berghei peptidyl-prolyl cis-trans isomerase FKBP35, putative Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 Get druggable targets OG5_126727 All targets in OG5_126727
Candida albicans hypothetical protein Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania braziliensis peptidylprolyl isomerase-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania donovani fk506-binding protein 1-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania major fk506-binding protein 1-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania mexicana fk506-binding protein 1-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma japonicum ko:K09571 FK506-binding protein 4/5, putative Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A Get druggable targets OG5_126727 All targets in OG5_126727
Candida albicans one of two identical potential FKBP-type peptidyl-prolyl cis-trans isomerase genes Get druggable targets OG5_126727 All targets in OG5_126727
Plasmodium yoelii FK506-binding protein Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania braziliensis fk506-binding protein 1-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma mansoni immunophilin Get druggable targets OG5_126727 All targets in OG5_126727
Trichomonas vaginalis peptidylprolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Schistosoma japonicum FK506-binding protein 1A, putative Get druggable targets OG5_126727 All targets in OG5_126727
Leishmania infantum peptidylprolyl isomerase-like protein Get druggable targets OG5_126727 All targets in OG5_126727
Plasmodium knowlesi peptidyl-prolyl cis-trans isomerase FKBP35, putative Get druggable targets OG5_126727 All targets in OG5_126727
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative Get druggable targets OG5_126727 All targets in OG5_126727
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 Get druggable targets OG5_126727 All targets in OG5_126727
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative FK506 binding protein 1A, 12kDa 108 aa 107 aa 48.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0146 0.017
Leishmania major pyruvate kinase 0.0037 0.0043 0.0031
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0043 0.0035
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0159 0.0388 0.0438
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0098 0.0215 0.0202
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.3059 0.8597 0.8596
Toxoplasma gondii bromodomain-containing protein 0.0035 0.0038 0.0029
Schistosoma mansoni hexokinase 0.1917 0.5366 0.6241
Entamoeba histolytica aspartyl aminopeptidase, putative 0.008 0.0165 0.0228
Onchocerca volvulus 0.0046 0.0068 0.0126
Trypanosoma brucei transcription factor BTF3, putative 0.0039 0.0048 0.0037
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0283 0.0738 0.0825
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0044 0.005
Echinococcus granulosus caspase 3 0.0081 0.0167 0.0195
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.3059 0.8597 1
Leishmania major eukaryotic translation initiation factor-like 0.0038 0.0047 0.0035
Trichomonas vaginalis diphosphomevalonate decarboxylase, putative 0.0046 0.0068 0.0051
Echinococcus multilocularis global transcription activator snf2l2 0.0035 0.0038 0.0044
Schistosoma mansoni methyl-cpg binding protein mbd 0.0091 0.0196 0.0228
Onchocerca volvulus 0.1917 0.5366 1
Chlamydia trachomatis pyruvate kinase 0.0037 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0058 0.0103 0.0119
Brugia malayi Steroid receptor seven-up type 2 0.0055 0.0095 0.0111
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0067 0.0128 0.0149
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0472 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0044 0.0025
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0098 0.0215 0.024
Echinococcus granulosus L aminoadipate semialdehyde 0.0093 0.02 0.0233
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0157 0.0383 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0061 0.0044
Plasmodium vivax phosphomannomutase, putative 0.0265 0.0687 0.0768
Loa Loa (eye worm) MH2 domain-containing protein 0.0105 0.0235 0.0274
Plasmodium vivax M18 aspartyl aminopeptidase, putative 0.008 0.0165 0.0183
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi polybromodomain protein 0.0035 0.0038 0.0044
Brugia malayi N-terminal motif family protein 0.0192 0.048 0.0559
Trichomonas vaginalis hypothetical protein 0.0035 0.0038 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.0055 0.0095 0.0111
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni Smad4 0.0047 0.0071 0.0082
Loa Loa (eye worm) 6-phosphofructokinase 0.0581 0.1583 0.1842
Loa Loa (eye worm) MH2 domain-containing protein 0.0047 0.0071 0.0083
Schistosoma mansoni immunophilin 0.0086 0.0181 0.021
Trichomonas vaginalis conserved hypothetical protein 0.2391 0.6707 0.7494
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0157 0.0383 0.0427
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0203 0.0512 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0297 0.0285
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0012 0.0023
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0035 0.0039
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0057 0.01 0.0116
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0043 0.0024
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0012 0.0014
Toxoplasma gondii calcium binding egf domain-containing protein 0.0057 0.01 0.0098
Loa Loa (eye worm) hypothetical protein 0.0111 0.0252 0.0293
Plasmodium vivax 6-phosphofructokinase, putative 0.0157 0.0383 0.0427
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0043 0.0051
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0218 0.0197
Trypanosoma brucei polo-like protein kinase 0.1688 0.4716 0.4709
Loa Loa (eye worm) hypothetical protein 0.0034 0.0035 0.004
Leishmania major hexokinase, putative 0.1917 0.5366 0.536
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus diphosphomevalonate decarboxylase 0.0046 0.0068 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0055 0.0095 0.0111
Brugia malayi Kringle domain containing protein 0.0111 0.0252 0.0293
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0283 0.0738 0.0813
Loa Loa (eye worm) PHD-finger family protein 0.0156 0.038 0.0441
Loa Loa (eye worm) hexokinase 0.1203 0.3343 0.3889
Schistosoma mansoni CREB-binding protein 2 0.0035 0.0038 0.0043
Trypanosoma brucei Putative Phosphatase/Protein of unknown function DUF89, putative 0.08 0.2204 0.2195
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.051 0.1383 0.1609
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni immunophilin 0.0099 0.0219 0.0254
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Loa Loa (eye worm) hypothetical protein 0.0052 0.0084 0.0098
Schistosoma mansoni hypothetical protein 0.0085 0.0179 0.0208
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0057 0.01 0.0116
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0215 0.0203
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0067 0.0128 0.0143
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0297 0.0332
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0052 0.0085 0.0098
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Schistosoma mansoni protein phosphatase 2C 0.005 0.0081 0.0093
Schistosoma mansoni RAR-like nuclear receptor 0.0055 0.0095 0.011
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0093 0.02 0.0232
Entamoeba histolytica acyl-CoA synthetase, putative 0.0127 0.0297 0.0426
Toxoplasma gondii PHD-finger domain-containing protein 0.0051 0.0083 0.0079
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0 0.0001
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0012 0.0014
Brugia malayi hypothetical protein 0.0022 0 0.0001
Trypanosoma cruzi Bromodomain, putative 0.0035 0.0038 0.0016
Echinococcus multilocularis PH interacting protein 0.0035 0.0038 0.0044
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Trypsin family protein 0.0052 0.0084 0.0098
Toxoplasma gondii bromodomain-containing protein 0.0035 0.0038 0.0029
Brugia malayi glutaminase DH11.1 0.2861 0.8038 0.9349
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0128 0.0149
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0023
Onchocerca volvulus 0.0418 0.1123 0.2092
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi polo-like protein kinase, putative 0.1688 0.4716 0.4704
Brugia malayi Smad1 0.0105 0.0235 0.0274
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0059 0.0068
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0021 0.0025
Onchocerca volvulus 0.0037 0.0044 0.0081
Mycobacterium leprae Probable 6-phosphogluconolactonase DevB (6PGL) 0.0122 0.0284 0.0881
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0098 0.0215 0.0193
Loa Loa (eye worm) hypothetical protein 0.0127 0.0297 0.0346
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0157 0.0383 0.0432
Brugia malayi Protein kinase domain containing protein 0.0111 0.0252 0.0293
Echinococcus granulosus bromodomain containing 2 0.0035 0.0038 0.0044
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0157 0.0383 0.0415
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.013 0.0118
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.3059 0.8597 1
Echinococcus multilocularis transmembrane protease serine 3 0.0052 0.0084 0.0098
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0012 0.0014
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.013 0.0132
Trypanosoma brucei metacaspase MCA2 0.003 0.0022 0.001
Echinococcus granulosus glycoprotein Antigen 5 0.0052 0.0084 0.0098
Entamoeba histolytica ankyrin repeat protein, putative 0.0035 0.0038 0.0039
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.2057 0.5761 0.6442
Echinococcus granulosus PHD finger protein rhinoceros 0.0156 0.038 0.0441
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0035 0.0027
Brugia malayi Hexokinase family protein 0.1917 0.5366 0.6241
Loa Loa (eye worm) isocitrate dehydrogenase 0.0067 0.0128 0.0149
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0035 0.0076
Toxoplasma gondii calcium binding egf domain-containing protein 0.0057 0.01 0.0098
Loa Loa (eye worm) hypothetical protein 0.1308 0.364 0.4234
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0012 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.102 0.2826 0.3287
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.0038 0.0044
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0072 0.0143 0.0167
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.2057 0.5761 0.6701
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0003 0.0004
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0043 0.0081
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0044 0.0022
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0044 0.0037
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0055 0.0095 0.0111
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0044 0.0103
Echinococcus granulosus thioredoxin glutathione reductase 0.0099 0.0218 0.0254
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0 0.0001
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0044 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Leishmania major hypothetical protein, conserved 0.0035 0.0038 0.0026
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0297 0.0285
Echinococcus granulosus CREB binding protein 0.0035 0.0038 0.0044
Toxoplasma gondii hexokinase 0.1917 0.5366 0.5995
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Brugia malayi Pre-SET motif family protein 0.0033 0.0032 0.0038
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0044 0.0103
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0095 0.0111
Schistosoma mansoni bromodomain containing 0.0035 0.0038 0.0043
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0051 0.0083 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Giardia lamblia Diphosphomevalonate decarboxylase 0.0046 0.0068 0.0036
Onchocerca volvulus Arrow homolog 0.0057 0.01 0.0186
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0293
Entamoeba histolytica hypothetical protein 0.0117 0.0269 0.0385
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.0084 0.0098
Echinococcus multilocularis hexokinase type 2 0.1917 0.5366 0.6241
Loa Loa (eye worm) hypothetical protein 0.025 0.0647 0.0753
Toxoplasma gondii NAC domain-containing protein 0.0039 0.0048 0.0041
Echinococcus multilocularis hexokinase 0.1917 0.5366 0.6241
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.005 0.0081 0.0059
Loa Loa (eye worm) ICD-1 protein 0.0039 0.0048 0.0056
Echinococcus granulosus phd:f box containing protein 0.005 0.0081 0.0094
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0023
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0098 0.0215 0.025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0472 0.055
Trypanosoma cruzi hypothetical protein, conserved 0.3554 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0055 0.0095 0.0111
Schistosoma mansoni Smad4 0.0105 0.0235 0.0273
Loa Loa (eye worm) translation initiation factor 4E 0.0038 0.0047 0.0055
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1688 0.4716 0.5485
Mycobacterium leprae PROBABLE AMINOPEPTIDASE PEPC 0.008 0.0165 0.0495
Loa Loa (eye worm) hypothetical protein 0.0127 0.0297 0.0346
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0043 0.0022
Entamoeba histolytica acyl-coA synthetase, putative 0.0127 0.0297 0.0426
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0098 0.0215 0.0193
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0095 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0035 0.0038 0.0042
Brugia malayi PHD-finger family protein 0.0061 0.0111 0.013
Loa Loa (eye worm) MH1 domain-containing protein 0.0105 0.0235 0.0274
Schistosoma mansoni glutaminase 0.2861 0.8038 0.9349
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0055 0.0095 0.0111
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0146 0.017
Schistosoma mansoni transcription factor LCR-F1 0.0117 0.0269 0.0313
Loa Loa (eye worm) hypothetical protein 0.0057 0.01 0.0116
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0146 0.0134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0043 0.0031
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Loa Loa (eye worm) steroid hormone receptor 0.0055 0.0095 0.0111
Echinococcus granulosus Niemann Pick C1 protein 0.0294 0.0771 0.0897
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0158 0.0152
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Bm-MIF-1, identical 0.2391 0.6707 0.7802
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0406
Schistosoma mansoni caspase-3 (C14 family) 0.011 0.0251 0.0292
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0055 0.0095 0.0111
Loa Loa (eye worm) CBP-B 0.0035 0.0038 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0472 0.0549
Onchocerca volvulus 0.1203 0.3343 0.6231
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0283 0.0738 0.0803
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0 0.0001
Brugia malayi Niemann-Pick C1 protein precursor 0.0206 0.0521 0.0606
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0055 0.0095 0.011
Schistosoma mansoni hypothetical protein 0.0555 0.151 0.1756
Echinococcus granulosus Bromodomain containing protein 0.0035 0.0038 0.0044
Entamoeba histolytica phosphofructokinase, putative 0.0581 0.1583 0.2347
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0055 0.0095 0.011
Brugia malayi Hexokinase family protein 0.1203 0.3343 0.3889
Entamoeba histolytica phosphomannomutase, putative 0.0265 0.0687 0.1009
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0297 0.0346
Schistosoma mansoni bromodomain containing protein 0.0361 0.096 0.1116
Trypanosoma cruzi mevalonate-diphosphate decarboxylase, putative 0.0046 0.0068 0.0046
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0259 0.067 0.0767
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi PHD-finger family protein 0.0156 0.038 0.0441
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Onchocerca volvulus Cell death protein 3 homolog 0.003 0.0022 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0086 0.0181 0.021
Brugia malayi hypothetical protein 0.1435 0.4001 0.4653
Mycobacterium tuberculosis Conserved protein 0.0409 0.1097 0.3519
Echinococcus multilocularis phosphomannomutase 0.0265 0.0687 0.0799
Toxoplasma gondii phosphomannose isomerase type I protein 0.2057 0.5761 0.6437
Brugia malayi Trypsin-like protease protein 5 0.0052 0.0084 0.0098
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0192 0.0583
Plasmodium vivax basic transcription factor 3b, putative 0.0039 0.0048 0.0054
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0409 0.1097 0.1264
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0097
Onchocerca volvulus 0.0037 0.0044 0.0081
Brugia malayi diphosphomevalonate decarboxylase family protein 0.0046 0.0068 0.0079
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.013 0.0151
Loa Loa (eye worm) glutaminase 0.2861 0.8038 0.9349
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0044 0.0103
Treponema pallidum hexokinase (hxk) 0.1917 0.5366 0.6236
Brugia malayi hypothetical protein 0.0026 0.0012 0.0014
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.003 0.0022 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.064 0.175 0.2036
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0044 0.0032
Trypanosoma brucei PAB1-binding protein , putative 0.0162 0.0396 0.0384
Giardia lamblia Hypothetical protein 0.0035 0.0038 0.0003
Echinococcus multilocularis hexokinase 0.1917 0.5366 0.6241
Brugia malayi CHD4 protein 0.0023 0.0003 0.0004
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0035 0.0038 0.0018
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0581 0.1583 0.1573
Leishmania major hypothetical protein, conserved 0.08 0.2204 0.2195
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0146 0.017
Echinococcus multilocularis protein kinase C binding protein 1 0.0035 0.0038 0.0044
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0043 0.0024
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0035 0.0038 0.0044
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.3181 0.8943 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0012 0.0014
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0122 0.0284 0.0316
Onchocerca volvulus Protein ultraspiracle homolog 0.0055 0.0095 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi hypothetical protein 0.0026 0.0012 0.0014
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0012 0.0014
Trypanosoma cruzi polo-like protein kinase, putative 0.1688 0.4716 0.4704
Onchocerca volvulus 0.0127 0.0297 0.0554
Leishmania major basic transcription factor 3a, putative 0.0039 0.0048 0.0037
Mycobacterium ulcerans 6-phosphogluconolactonase 0.0122 0.0284 0.0316
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0409 0.1097 0.1077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0044 0.0103
Echinococcus multilocularis glycoprotein Antigen 5 0.0052 0.0084 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Echinococcus granulosus caspase 2 0.003 0.0022 0.0026
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0035 0.0015
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0021 0.0025
Entamoeba histolytica hypothetical protein 0.0026 0.0012 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi MH2 domain containing protein 0.0105 0.0235 0.0274
Echinococcus granulosus mothers against decapentaplegic 6 0.0047 0.0071 0.0083
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0043 0.0102
Trypanosoma cruzi hexokinase, putative 0.1917 0.5366 0.5355
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0038 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0047 0.0071 0.0083
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0044 0.0035
Trichomonas vaginalis fk506-binding protein, putative 0.0098 0.0215 0.0216
Trypanosoma cruzi bromodomain factor 2 protein 0.0035 0.0038 0.0016
Loa Loa (eye worm) hypothetical protein 0.0438 0.1177 0.1369
Onchocerca volvulus 0.1917 0.5366 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0035 0.0038 0.0018
Plasmodium falciparum thioredoxin reductase 0.0099 0.0218 0.0244
Schistosoma mansoni thyroid hormone receptor 0.0055 0.0095 0.011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.029 0.0337
Onchocerca volvulus 0.0367 0.0977 0.182
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0203 0.0512 0.0595
Entamoeba histolytica serine/threonine protein kinase, putative 0.1688 0.4716 0.7025
Loa Loa (eye worm) Smad1 0.0105 0.0235 0.0274
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0035 0.0038 0.0018
Entamoeba histolytica transcription factor BTF3, putative 0.0039 0.0048 0.0055
Toxoplasma gondii hypothetical protein 0.0035 0.0038 0.0029
Trypanosoma brucei glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0272
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni hypothetical protein 0.0156 0.038 0.0441
Echinococcus granulosus global transcription activator snf2l2 0.0035 0.0038 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0081 0.0094
Giardia lamblia Kinase, PLK 0.1688 0.4716 0.5255
Echinococcus granulosus slit 2 protein 0.0022 0.0001 0.0001
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.011 0.0128
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Giardia lamblia Hypothetical protein 0.0035 0.0038 0.0003
Chlamydia trachomatis 6-phosphogluconolactonase 0.0122 0.0284 0.0316
Trypanosoma cruzi Bromodomain, putative 0.0035 0.0038 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium ulcerans hypothetical protein 0.0127 0.0297 0.0332
Trypanosoma cruzi aspartyl aminopeptidase, putative 0.008 0.0165 0.0143
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0984 0.2724 0.2708
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi bromodomain-containing protein 3 0.0035 0.0038 0.0016
Schistosoma mansoni hypothetical protein 0.0052 0.0084 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Schistosoma mansoni hypothetical protein 0.0085 0.0179 0.0208
Echinococcus granulosus Smad4 0.0105 0.0235 0.0274
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0032 0.0023
Loa Loa (eye worm) hypothetical protein 0.0057 0.01 0.0116
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0035 0.0038 0.007
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0259 0.067 0.2136
Leishmania major 4-coumarate:coa ligase-like protein 0.0127 0.0297 0.0285
Schistosoma mansoni hypothetical protein 0.0051 0.0083 0.0095
Leishmania major metacaspase, putative 0.003 0.0022 0.001
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0409 0.1097 0.1264
Echinococcus granulosus GPCR family 2 0.0203 0.0512 0.0595
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Plasmodium vivax acyl-CoA synthetase, putative 0.0095 0.0206 0.023
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.3181 0.8943 1
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.008 0.0165 0.0191
Trypanosoma cruzi phosphomannose isomerase, putative 0.2057 0.5761 0.5752
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0146 0.017
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0043
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.1998 0.5594 0.625
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi metallo-peptidase, Clan MH, Family M20 0.008 0.0165 0.0143
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0044 0.0024
Brugia malayi Bromodomain containing protein 0.0227 0.0582 0.0676
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0098 0.0215 0.025
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0112 0.0131
Echinococcus granulosus methyl CpG binding domain protein 2 0.0091 0.0196 0.0228
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0098 0.0215 0.025
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0409 0.1097 0.1264
Trypanosoma cruzi mevalonate-diphosphate decarboxylase, putative 0.0046 0.0068 0.0046
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0067 0.0128 0.0149
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.013 0.0382
Trypanosoma cruzi Putative Phosphatase/Protein of unknown function DUF89, putative 0.08 0.2204 0.2187
Plasmodium vivax 6-phosphofructokinase, putative 0.0157 0.0383 0.0427
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0098 0.0215 0.0236
Loa Loa (eye worm) glutaminase 2 0.2861 0.8038 0.9349
Brugia malayi latrophilin 2 splice variant baaae 0.0438 0.1177 0.1369
Schistosoma mansoni 6-phosphogluconolactonase 0.0122 0.0284 0.0329
Toxoplasma gondii histone lysine demethylase JMJD6a 0.005 0.0081 0.0077
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0035 0.0026
Onchocerca volvulus 0.0055 0.0095 0.0177
Schistosoma mansoni nuclear receptor 0.0026 0.0012 0.0014
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0052 0.0084 0.0098
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Schistosoma mansoni caspase-7 (C14 family) 0.003 0.0022 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0035 0.0023
Plasmodium vivax ataxin-2 like protein, putative 0.0162 0.0396 0.0442
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0003 0.0003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0251 0.0648 0.2063
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0095 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0037 0.0044 0.0037
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma brucei beta lactamase 0.0124 0.029 0.0278
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0035 1
Echinococcus multilocularis caspase 3 0.0081 0.0167 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0025 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Echinococcus granulosus JmjC domain containing protein 4 0.005 0.0081 0.0094
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0012 0.0014
Echinococcus granulosus Niemann Pick C1 protein 0.0206 0.0521 0.0606
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0146 0.0134
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Brugia malayi jmjC domain containing protein 0.005 0.0081 0.0094
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi beta-NAC-like protein 0.0039 0.0048 0.0056
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0044 0.0024
Loa Loa (eye worm) diphosphomevalonate decarboxylase 0.0037 0.0043 0.005
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0043
Giardia lamblia Glucosamine-6-phosphate deaminase 0.0122 0.0284 0.0279
Trichomonas vaginalis CAMK family protein kinase 0.0835 0.2303 0.2557
Trichomonas vaginalis lymphoid specific helicase, putative 0.0035 0.0038 0.0018
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0044 0.0051
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Onchocerca volvulus 0.0052 0.0084 0.0157
Echinococcus multilocularis thyroid hormone receptor alpha 0.0055 0.0095 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0188 0.0187
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0083 0.0092
Brugia malayi hypothetical protein 0.0052 0.0084 0.0098
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0472 0.055
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0035 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.0162 0.0396 0.0375
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0086 0.0181 0.021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0055 0.0095 0.0111
Schistosoma mansoni hypothetical protein 0.0203 0.0512 0.0595
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.001 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus multilocularis isocitrate dehydrogenase 0.0067 0.0128 0.0149
Plasmodium falciparum cysteine repeat modular protein 1 0.0111 0.0252 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0044 0.0035
Echinococcus granulosus pyruvate kinase 0.0037 0.0043 0.0051
Brugia malayi RNA recognition motif domain containing protein 0.0814 0.2243 0.2609
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0124 0.029 0.0901
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Plasmodium falciparum thioredoxin reductase 0.0034 0.0035 0.0039
Onchocerca volvulus Serine\/threonine kinase homolog 0.1688 0.4716 0.8789
Loa Loa (eye worm) hypothetical protein 0.0108 0.0245 0.0285
Plasmodium vivax SET domain containing protein 0.0036 0.0041 0.0046
Schistosoma mansoni methyl-cpg binding protein mbd 0.0091 0.0196 0.0228
Leishmania major aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 0.008 0.0165 0.0153
Brugia malayi CHE-14 protein 0.0088 0.0188 0.0219
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0097
Echinococcus multilocularis mothers against decapentaplegic 2 0.0047 0.0071 0.0083
Onchocerca volvulus 0.0052 0.0084 0.0157
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0035 1
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Plasmodium falciparum hexokinase 0.1917 0.5366 0.6
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0378 0.1009 0.1173
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0038 0.0047 0.0055
Plasmodium falciparum phd finger protein, putative 0.0156 0.038 0.0424
Loa Loa (eye worm) TK/ROR protein kinase 0.0111 0.0252 0.0293
Loa Loa (eye worm) latrophilin receptor protein 2 0.0203 0.0512 0.0595
Brugia malayi jmjC domain containing protein 0.005 0.0081 0.0094
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0055 0.0095 0.0111
Loa Loa (eye worm) jmjC domain-containing protein 0.0322 0.0849 0.0988
Trypanosoma brucei metacaspase MCA3 0.003 0.0022 0.001
Brugia malayi polybromodomain protein 0.0035 0.0038 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0053
Mycobacterium ulcerans hypothetical protein 0.0052 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0555 0.151 0.1756
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0105 0.0235 0.0273
Loa Loa (eye worm) hypothetical protein 0.0418 0.1123 0.1306
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0127 0.0297 0.0332
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0038 0.0047 0.0025
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.005 0.0081 0.0094
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0043 0.0051
Echinococcus multilocularis phd:f box containing protein 0.005 0.0081 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0262
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0044 0.0025
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0028
Onchocerca volvulus 0.0037 0.0044 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Schistosoma mansoni tar DNA-binding protein 0.0814 0.2243 0.2609
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0032 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0048 0.003
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0044 0.0048
Plasmodium falciparum basic transcription factor 3b, putative 0.0039 0.0048 0.0054
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0035 0.0038 0.0026
Plasmodium vivax glutathione reductase, putative 0.0099 0.0218 0.0244
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Echinococcus granulosus pyruvate kinase 0.0037 0.0043 0.0051
Onchocerca volvulus 0.0052 0.0084 0.0157
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0044 0.0051
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0041
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.2057 0.5761 0.6701
Giardia lamblia Histone acetyltransferase GCN5 0.0247 0.0639 0.0677
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.005 0.0081 0.0069
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0043 0.0048
Echinococcus multilocularis JmjC domain containing protein 4 0.005 0.0081 0.0094
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0012 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Leishmania major mevalonate-diphosphate decarboxylase, putative 0.0046 0.0068 0.0056
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0052 0.0084 0.0097
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0342 0.0905 0.1053
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.2057 0.5761 0.6701
Entamoeba histolytica hexokinase 1 0.1917 0.5366 0.7996
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0028
Echinococcus multilocularis Bromodomain containing protein 0.0035 0.0038 0.0044
Trypanosoma brucei Bromodomain, putative 0.0035 0.0038 0.0026
Loa Loa (eye worm) 6-phosphofructokinase 0.0581 0.1583 0.1842
Echinococcus multilocularis GPCR, family 2 0.0203 0.0512 0.0595
Trypanosoma brucei 6-phosphogluconolactonase 0.0122 0.0284 0.0272
Echinococcus granulosus expressed conserved protein 0.0193 0.0486 0.0565
Onchocerca volvulus 0.0111 0.0252 0.047
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0035 0.0015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.064 0.175 0.2036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0072 0.0143 0.0167
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0035 0.0023
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.3181 0.8943 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0098 0.0215 0.025
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.102 0.2826 0.3287
Loa Loa (eye worm) BRM protein 0.0035 0.0038 0.0044
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0203 0.0512 0.0595
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0159 0.0388 0.122
Loa Loa (eye worm) hexokinase 0.1917 0.5366 0.6241
Plasmodium falciparum ataxin-2 like protein, putative 0.0162 0.0396 0.0442
Trichomonas vaginalis macrophage migration inhibitory factor, mif, putative 0.2391 0.6707 0.7494
Plasmodium falciparum bromodomain protein 1 0.0035 0.0038 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0055 0.0095 0.0111
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0038 0.0042
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0012 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0048 0.003
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Calcium binding EGF domain containing protein 0.0057 0.01 0.0116
Plasmodium falciparum pyruvate kinase 0.0037 0.0043 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0581 0.1583 0.175
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0581 0.1583 0.1565
Echinococcus granulosus geminin 0.0555 0.151 0.1756
Brugia malayi Trypsin family protein 0.0418 0.1123 0.1306
Echinococcus granulosus Mastin 0.0052 0.0084 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0814 0.2243 0.2609
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0025
Echinococcus granulosus jumonji domain containing 1A 0.005 0.0081 0.0094
Loa Loa (eye worm) jmjC domain-containing protein 0.0199 0.0501 0.0583
Echinococcus granulosus PH interacting protein 0.0035 0.0038 0.0044
Plasmodium falciparum macrophage migration inhibitory factor 0.2391 0.6707 0.75
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.008 0.0165 0.016
Brugia malayi ATPase, AAA family protein 0.0035 0.0038 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0061 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0068 0.0079
Trypanosoma brucei mevalonate-diphosphate decarboxylase 0.0046 0.0068 0.0056
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0055 0.0095 0.0177
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0044 0.0037
Trypanosoma cruzi Putative Phosphatase/Protein of unknown function DUF89, putative 0.08 0.2204 0.2187
Entamoeba histolytica hypothetical protein 0.0035 0.0038 0.0039
Trypanosoma brucei Bromodomain, putative 0.0035 0.0038 0.0026
Mycobacterium tuberculosis Probable dehydrogenase 0.0226 0.0577 0.1832
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Brugia malayi Bromodomain containing protein 0.0191 0.0479 0.0557
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Brugia malayi serine/threonine-protein kinase plk-2 0.1688 0.4716 0.5485
Loa Loa (eye worm) hypothetical protein 0.1435 0.4001 0.4653
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0044 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium ulcerans hypothetical protein 0.0409 0.1097 0.1264
Brugia malayi steroid hormone receptor 0.0055 0.0095 0.0111
Brugia malayi mothers against decapentaplegic homolog 3 0.0047 0.0071 0.0083
Brugia malayi jmjC domain containing protein 0.051 0.1383 0.1609
Trypanosoma brucei ISWI complex protein 0.0082 0.017 0.0158
Schistosoma mansoni hypothetical protein 0.011 0.0251 0.0291
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.029 0.0337
Schistosoma mansoni hypothetical protein 0.0117 0.0269 0.0313
Trypanosoma cruzi Bromodomain, putative 0.0035 0.0038 0.0016
Onchocerca volvulus 0.0035 0.0038 0.007
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0098 0.0215 0.0202
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0012 0.0014
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0037 0.0044 0.0025
Echinococcus granulosus smad 0.0105 0.0235 0.0274
Loa Loa (eye worm) aspartyl aminopeptidase 0.008 0.0165 0.0191
Brugia malayi MH1 domain containing protein 0.0058 0.0103 0.0119
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.0044 0.0051
Toxoplasma gondii PHD-finger domain-containing protein 0.0156 0.038 0.0412
Trypanosoma cruzi phosphomannomutase, putative 0.0265 0.0687 0.0667
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0095 0.0206 0.0226
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Onchocerca volvulus 0.0052 0.0084 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0835 0.2303 0.2557
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0252 0.0231
Brugia malayi MH2 domain containing protein 0.154 0.4296 0.4997
Echinococcus multilocularis CREB binding protein 0.0035 0.0038 0.0044
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0012 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0055 0.0095 0.0111
Onchocerca volvulus 0.0022 0 0.0001
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0037 0.0044 0.0025
Echinococcus multilocularis 6 phosphofructokinase 0.0581 0.1583 0.1842
Onchocerca volvulus 0.0035 0.0038 0.007
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0044 0.0048
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0027
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0021 0.0025
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0043 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0055 0.0095 0.0111
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0067 0.0128 0.0149
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0012 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0205 0.0519 0.0604
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0099 0.0218 0.0669
Brugia malayi conserved hypotetical protein 0.0026 0.0012 0.0014
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0215 0.0193
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0581 0.1583 0.1841
Brugia malayi hypothetical protein 0.0117 0.0269 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0052 0.0084 0.0098
Trypanosoma cruzi Bromodomain, putative 0.0035 0.0038 0.0016
Toxoplasma gondii bromodomain-containing protein 0.0035 0.0038 0.0029
Toxoplasma gondii phosphomannomutase 0.0265 0.0687 0.0756
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0035 0.0041
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.0044 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus caspase 8 0.003 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0162 0.0396 0.046
Schistosoma mansoni hypothetical protein 0.0085 0.0179 0.0208
Brugia malayi nuclear hormone receptor 0.0026 0.0012 0.0014
Trichomonas vaginalis hypothetical protein 0.0037 0.0044 0.0025
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0038 0.0047 0.0028
Entamoeba histolytica acetyltransferase, GNAT family 0.0247 0.0639 0.0937
Loa Loa (eye worm) glutathione reductase 0.0099 0.0218 0.0254
Brugia malayi phosphofructokinase 0.0581 0.1583 0.1842
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0025 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0047 0.0071 0.0083
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0035 0.0023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0021 0.0025
Echinococcus granulosus mothers against decapentaplegic 5 0.0105 0.0235 0.0274
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0127 0.0297 0.0332
Loa Loa (eye worm) hypothetical protein 0.003 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus Tolloid protein 1 0.0057 0.01 0.0116
Echinococcus granulosus transcription factor btf3 0.0039 0.0048 0.0056
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni phd/f-box containing protein 0.005 0.0081 0.0093
Loa Loa (eye worm) hypothetical protein 0.0095 0.0206 0.024
Echinococcus multilocularis mannose 6 phosphate isomerase 0.2057 0.5761 0.6701
Trypanosoma brucei trypanothione reductase 0.0099 0.0218 0.0207
Schistosoma mansoni bromodomain containing protein 0.0035 0.0038 0.0043
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0098 0.0215 0.024
Schistosoma mansoni zinc finger protein 0.0127 0.0298 0.0346
Mycobacterium ulcerans diphosphomevalonate decarboxylase 0.0046 0.0068 0.0065
Onchocerca volvulus Brd8 homolog 0.0035 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0048 0.003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0037 0.0044 0.0037
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0035 0.0039
Brugia malayi nuclear receptor RXR 0.0029 0.0021 0.0025
Trypanosoma brucei aspartyl aminopeptidase, putative 0.008 0.0165 0.0153
Loa Loa (eye worm) phosphofructokinase 0.0581 0.1583 0.1842
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0055 0.0095 0.0111
Echinococcus granulosus transmembrane protease serine 3 0.0052 0.0084 0.0098
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0156 0.038 0.0441
Echinococcus multilocularis Niemann Pick C1 protein 0.0294 0.0771 0.0897
Echinococcus multilocularis mothers against decapentaplegic 6 0.0047 0.0071 0.0083
Entamoeba histolytica hypothetical protein 0.0117 0.0269 0.0385
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0025
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0012 0.0014
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0067 0.0128 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0127 0.0297 0.0925
Toxoplasma gondii isocitrate dehydrogenase 0.0067 0.0128 0.013
Echinococcus multilocularis mothers against decapentaplegic 5 0.0105 0.0235 0.0274
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0814 0.2243 0.2609
Entamoeba histolytica phosphofructokinase, putative 0.0581 0.1583 0.2347
Schistosoma mansoni 6-phosphogluconolactonase 0.0122 0.0284 0.0329
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0051 0.0083 0.0079
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus Bromodomain containing protein 0.0035 0.0038 0.0044
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0128 0.0106
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0105 0.0235 0.0274
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.029 0.0338
Loa Loa (eye worm) hypothetical protein 0.0043 0.0061 0.0071
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0043
Onchocerca volvulus 0.0035 0.0038 0.007
Schistosoma mansoni tar DNA-binding protein 0.0814 0.2243 0.2609
Plasmodium falciparum phosphomannomutase, putative 0.0265 0.0687 0.0768
Trypanosoma brucei phosphomannose isomerase 0.2057 0.5761 0.5756
Leishmania major fk506-binding protein 1-like protein 0.0098 0.0215 0.0203
Giardia lamblia PHD finger protein 15 0.0156 0.038 0.0386
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0035 0.0013
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.3181 0.8943 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0012 0.0014
Toxoplasma gondii bromodomain-containing protein 0.0035 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.01 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0032 0.0037
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0044 0.0022
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0044 0.0025
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0071 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Loa Loa (eye worm) thioredoxin reductase 0.0099 0.0218 0.0254
Loa Loa (eye worm) hypothetical protein 0.0037 0.0043 0.0051
Brugia malayi isocitrate dehydrogenase 0.0067 0.0128 0.0149
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0044 0.0022
Entamoeba histolytica phosphomannose isomerase, putative 0.2057 0.5761 0.8586
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0055 0.0095 0.011
Loa Loa (eye worm) RNA binding protein 0.0814 0.2243 0.2609
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0121 0.0279 0.0325
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni transcription factor btf3 0.0039 0.0048 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0095 0.0111
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.0044 0.0103
Giardia lamblia Glucosamine-6-phosphate deaminase 0.0122 0.0284 0.0279
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0021 0.0024
Brugia malayi jmjC domain containing protein 0.005 0.0081 0.0094
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0418 0.1123 0.1306
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.3059 0.8597 1
Brugia malayi hexokinase type II 0.061 0.1664 0.1935
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0044 0.0037
Brugia malayi nuclear receptor NHR-67 0.0026 0.0012 0.0014
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1688 0.4716 0.5485
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0047 0.0071 0.0132
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0044 0.0037
Leishmania major glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0272
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0052 0.0084 0.0098
Plasmodium falciparum glutathione reductase 0.0099 0.0218 0.0244
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0067 0.0128 0.0143
Schistosoma mansoni pyruvate kinase 0.0037 0.0043 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0095 0.0111
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0581 0.1583 0.5096
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0146 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0029 0.0055
Leishmania major phosphomannose isomerase 0.2057 0.5761 0.5756
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0127 0.0297 0.0332
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0012 0.0014
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0146 0.017
Trypanosoma brucei phosphomannomutase 0.0265 0.0687 0.0676
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0127 0.0297 0.0332
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0158 0.0184
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0051 0.0083 0.0092
Loa Loa (eye worm) hypothetical protein 0.0203 0.0512 0.0595
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0095 0.011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0157 0.0383 0.0427
Schistosoma mansoni hypothetical protein 0.0052 0.0084 0.0097
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.005 0.0081 0.0077
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0012 0.0014
Plasmodium vivax bromodomain protein, putative 0.0035 0.0038 0.0042
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0043 0.0081
Trichomonas vaginalis set domain proteins, putative 0.0264 0.0685 0.0743
Loa Loa (eye worm) hypothetical protein 0.0095 0.0206 0.024
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0057 0.01 0.0116
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Loa Loa (eye worm) PHD-finger family protein 0.011 0.0251 0.0291
Trypanosoma brucei Bromodomain, putative 0.0035 0.0038 0.0026
Echinococcus multilocularis ecdysone induced protein 78C 0.0055 0.0095 0.0111
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0036 0.0041 0.0033
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.2057 0.5761 0.6442
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0325 0.0859 0.1266
Echinococcus multilocularis RUN 0.0022 0 0.0001
Echinococcus multilocularis Smad4 0.0105 0.0235 0.0274
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0043 0.0081
Giardia lamblia Kinase, putative 0.0035 0.0038 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0055 0.0095 0.0111
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0044 0.0103
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.0472 0.055
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.1115 0.3095 1
Echinococcus granulosus lysine specific demethylase 6a 0.005 0.0081 0.0094
Loa Loa (eye worm) hypothetical protein 0.0095 0.0206 0.024
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0038 0.0047 0.0035
Schistosoma mansoni hypothetical protein 0.0203 0.0512 0.0595
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0099 0.0219 0.031
Echinococcus granulosus hexokinase type 2 0.1917 0.5366 0.6241
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0044 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0162 0.0396 0.0375
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0098 0.0215 0.0216
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0038 0.0047 0.0039
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0409 0.1097 0.1086
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0192 0.0583
Echinococcus multilocularis enteropeptidase 0.0052 0.0084 0.0098
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0128 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0055 0.0095 0.011
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0203 0.0512 0.0595
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0297 0.0332
Echinococcus multilocularis Bromodomain containing protein 0.0035 0.0038 0.0044
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0325 0.0859 0.1266
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0099 0.0219 0.031
Brugia malayi photoreceptor-specific nuclear receptor 0.0055 0.0095 0.0111
Toxoplasma gondii phosphofructokinase PFKII 0.0157 0.0383 0.0415
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0035 0.0023
Treponema pallidum NADH oxidase 0.0034 0.0035 0.0027
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0055 0.0095 0.0111
Echinococcus multilocularis fk506 binding protein 0.0098 0.0215 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Schistosoma mansoni hypothetical protein 0.0203 0.0512 0.0595
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.029 0.0338
Echinococcus granulosus hexokinase 0.1917 0.5366 0.6241
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0044 0.0032
Onchocerca volvulus 0.0022 0 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Bromodomain containing protein 0.0423 0.1137 0.1322
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0097
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.0219 0.0255
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0044 0.0032
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.1061 0.2942 0.9504
Loa Loa (eye worm) hypothetical protein 0.0061 0.0111 0.013
Trypanosoma cruzi hypothetical protein, conserved 0.3554 1 1
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0122 0.0284 0.0262
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0095 0.0111
Brugia malayi hypothetical protein 0.0022 0 0.0001
Schistosoma mansoni zinc finger protein 0.0082 0.017 0.0197
Echinococcus granulosus protein kinase C binding protein 1 0.0035 0.0038 0.0044
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0098 0.0215 0.0203
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Loa Loa (eye worm) hexokinase type II 0.1917 0.5366 0.6241
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0035 0.0038 0.0026
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0157 0.0383 0.0432
Leishmania major eukaryotic translation initiation factor-like protein 0.0038 0.0047 0.0035
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0192 0.0583
Echinococcus multilocularis caspase 2 0.003 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) trypsin family protein 0.0052 0.0084 0.0098
Onchocerca volvulus 0.1917 0.5366 1
Schistosoma mansoni nuclear hormone receptor 0.0055 0.0095 0.011
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0226 0.0577 0.1832
Brugia malayi 6-phosphogluconolactonase family protein 0.0122 0.0284 0.033
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0012 0.0023
Trypanosoma brucei mevalonate diphosphate decarboxylase 0.0046 0.0068 0.0056
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0059 0.0068
Echinococcus multilocularis citrate lyase subunit beta protein 0.0409 0.1097 0.1276
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0071 0.0055
Echinococcus multilocularis protein patched 0.0088 0.0188 0.0219
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0409 0.1097 0.1205
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.001 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Onchocerca volvulus 0.0093 0.02 0.0373
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.008 0.0165 0.0191
Entamoeba histolytica phosphofructokinase, putative 0.0581 0.1583 0.2347
Echinococcus multilocularis bromodomain containing 2 0.0035 0.0038 0.0044
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0035 0.0038 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Echinococcus multilocularis jumonji domain containing protein 0.0217 0.0552 0.0642
Loa Loa (eye worm) hexokinase 0.1917 0.5366 0.6241
Brugia malayi Thioredoxin reductase 0.0099 0.0218 0.0254
Trypanosoma brucei Metacaspase-4 0.003 0.0022 0.001
Loa Loa (eye worm) 6-phosphogluconolactonase 0.0122 0.0284 0.033
Brugia malayi acetyltransferase, GNAT family protein 0.0931 0.2572 0.2992
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0035 0.0038 0.0043
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.3181 0.8943 1
Loa Loa (eye worm) FKBP5 protein 0.0098 0.0215 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0055 0.0095 0.0111
Echinococcus multilocularis zinc finger protein 0.0127 0.0298 0.0347
Schistosoma mansoni diphosphomevalonate decarboxylase 0.0046 0.0068 0.0078
Brugia malayi Trypsin family protein 0.0052 0.0084 0.0098
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Loa Loa (eye worm) hypothetical protein 0.0052 0.0084 0.0098
Loa Loa (eye worm) hypothetical protein 0.0093 0.02 0.0233
Echinococcus granulosus neuropeptide s receptor 0.0515 0.1395 0.1623
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0226 0.0577 0.1832
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0206 0.0521 0.0761
Trypanosoma cruzi Bromodomain factor 1 0.0035 0.0038 0.0016
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0128 0.0116
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0418 0.1123 0.1305
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0035 0.0027
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0146 0.0201
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Leishmania major hypothetical protein, conserved 0.005 0.0081 0.0069
Echinococcus multilocularis slit 2 protein 0.0022 0.0001 0.0001
Leishmania major hexokinase, putative 0.1917 0.5366 0.536
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0931 0.2572 0.2992
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0057 0.01 0.0116
Schistosoma mansoni hypothetical protein 0.0082 0.017 0.0197
Echinococcus multilocularis pyruvate kinase 0.0029 0.0021 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0406 0.1086 0.1263
Mycobacterium ulcerans lipoprotein LpqF 0.0124 0.029 0.0323
Echinococcus granulosus TGF beta signal transducer SmadC 0.0105 0.0235 0.0274
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0581 0.1583 0.183
Schistosoma mansoni smad 0.0105 0.0235 0.0273
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni 6-phosphofructokinase 0.0581 0.1583 0.1841
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0209 0.053 0.0616
Trichomonas vaginalis phosphofructokinase, putative 0.0581 0.1583 0.175
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.2057 0.5761 0.6433
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Echinococcus granulosus hexokinase 0.1917 0.5366 0.6241
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.3181 0.8943 1
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Echinococcus multilocularis neuropeptide receptor A26 0.0515 0.1395 0.1623
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0035 0.0039
Echinococcus multilocularis geminin 0.0555 0.151 0.1756
Brugia malayi glucose-6-phosphate dehydrogenase 0.3059 0.8597 1
Brugia malayi nuclear receptor NHR-88 0.0055 0.0095 0.0111
Echinococcus granulosus enteropeptidase 0.0052 0.0084 0.0098
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0048 0.0027
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.3059 0.8597 0.8596
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0117 0.0269 0.0313
Loa Loa (eye worm) hexokinase 0.0593 0.1618 0.1882
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0055 0.0095 0.0111
Entamoeba histolytica hexokinase 2 0.1917 0.5366 0.7996
Brugia malayi MH1 domain containing protein 0.0105 0.0235 0.0274
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.003 0.0022 0.0011
Schistosoma mansoni polybromo-1 0.0035 0.0038 0.0043
Loa Loa (eye worm) hypothetical protein 0.061 0.1664 0.1935
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0581 0.1583 0.5096
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0003 0.0004
Schistosoma mansoni glucosamine-6-phosphate isomerase 0.0122 0.0284 0.0329
Brugia malayi hypothetical protein 0.0029 0.0021 0.0025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0061 0.0114
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Brugia malayi hypothetical protein 0.0162 0.0396 0.046
Onchocerca volvulus 0.0052 0.0084 0.0157
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0038 0.0047 0.0028
Schistosoma mansoni smad 0.0047 0.0071 0.0082
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0146 0.0125
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0203 0.0512 0.0595
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.1115 0.3095 1
Loa Loa (eye worm) MH2 domain-containing protein 0.154 0.4296 0.4997
Echinococcus granulosus chromobox protein 1 0.0078 0.0158 0.0184
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0038 0.0047 0.0028
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0192 0.0482 0.0561
Echinococcus granulosus histone acetyltransferase KAT2B 0.0283 0.0738 0.0859
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0095 0.0111
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0037 0.0044 0.0025
Schistosoma mansoni patched 1 0.0088 0.0188 0.0219
Mycobacterium ulcerans acyl-CoA synthetase 0.0127 0.0297 0.0332
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0283 0.0738 0.0813
Plasmodium falciparum acyl-CoA synthetase 0.0095 0.0206 0.023
Trypanosoma brucei hypothetical protein, conserved 0.3554 1 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0418 0.1123 0.1305
Echinococcus multilocularis Niemann Pick C1 protein 0.0206 0.0521 0.0606
Echinococcus multilocularis Tolloid protein 1 0.0057 0.01 0.0116
Schistosoma mansoni tar DNA-binding protein 0.0814 0.2243 0.2609
Brugia malayi ecdysteroid receptor 0.0055 0.0095 0.0111
Echinococcus granulosus lysine specific demethylase 5A 0.0199 0.0501 0.0583
Entamoeba histolytica macrophage migration inhibitory factor-like protein 0.2391 0.6707 1
Echinococcus multilocularis tissue type plasminogen activator 0.0111 0.0252 0.0293
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0043 0.0051
Leishmania major hypothetical protein, conserved 0.0035 0.0038 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.013 0.0137
Trichomonas vaginalis immunophilin, putative 0.0098 0.0215 0.0216
Brugia malayi MH1 domain containing protein 0.0105 0.0235 0.0274
Echinococcus multilocularis caspase 0.011 0.0251 0.0292
Mycobacterium ulcerans glutaminase 0.2861 0.8038 0.9348
Trichomonas vaginalis phosphofructokinase, putative 0.0581 0.1583 0.175
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0127 0.0297 0.0925
Echinococcus granulosus hexokinase 0.1917 0.5366 0.6241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.013 0.015
Brugia malayi RNA binding protein 0.0814 0.2243 0.2609
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0035 0.0038 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Schistosoma mansoni pyruvate kinase 0.0037 0.0043 0.005
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0121 0.0279 0.0325
Schistosoma mansoni hypothetical protein 0.0111 0.0252 0.0293
Echinococcus multilocularis pyruvate kinase 0.0037 0.0043 0.0051
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0038 0.0047 0.0025
Brugia malayi nuclear receptor NHR-88 0.0026 0.0012 0.0014
Schistosoma mansoni transcription initiation factor tfiid 0.0035 0.0038 0.0043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Onchocerca volvulus Hexokinase homolog 0.1203 0.3343 0.6231
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0035 0.0038 0.0043
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0044 0.0103
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.011 0.0128
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0112 0.0131
Toxoplasma gondii LsmAD domain-containing protein 0.0162 0.0396 0.043
Leishmania major peptidylprolyl isomerase-like protein 0.0098 0.0215 0.0203
Plasmodium falciparum metacaspase-like protein 0.003 0.0022 0.0024
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0098 0.0215 0.0216
Mycobacterium ulcerans 6-phosphofructokinase 0.0581 0.1583 0.183
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0409 0.1097 0.1077
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0035 0.0038 0.0018
Leishmania major hypothetical protein, conserved 0.0082 0.017 0.0158
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0297 0.0346
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0093 0.02 0.0233
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0035 0.0026
Echinococcus multilocularis lysine specific demethylase 6a 0.005 0.0081 0.0094
Plasmodium falciparum JmjC domain-containing protein, putative 0.005 0.0081 0.009
Echinococcus granulosus chromobox protein 1 0.0078 0.0158 0.0184
Brugia malayi EGF-like domain containing protein 0.0022 0.0001 0.0001
Echinococcus granulosus jumonji domain containing protein 0.0217 0.0552 0.0642
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.003 0.0022 0.0011
Echinococcus granulosus mannose 6 phosphate isomerase 0.2057 0.5761 0.6701
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0023
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0012 0.0014
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0409 0.1097 0.3519
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0012 0.0014
Onchocerca volvulus Slit protein homolog 0.0022 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Echinococcus multilocularis aspartyl aminopeptidase 0.008 0.0165 0.0191
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Heterochromatin protein 1 0.0078 0.0158 0.0184
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0251 0.0648 0.2063
Leishmania major pyruvate kinase 0.0037 0.0043 0.0031
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.024 0.0618 0.0719
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0012 0.0014
Giardia lamblia Transcription regulatory protein SNF2 0.0035 0.0038 0.0003
Echinococcus multilocularis chromobox protein 1 0.0078 0.0158 0.0184
Schistosoma mansoni chromobox protein 0.0078 0.0158 0.0183
Schistosoma mansoni tar DNA-binding protein 0.0814 0.2243 0.2609
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.3059 0.8597 1
Toxoplasma gondii kringle domain-containing protein 0.0111 0.0252 0.0269
Echinococcus multilocularis pyruvate kinase 0.0037 0.0043 0.0051
Loa Loa (eye worm) hypothetical protein 0.003 0.0022 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0156 0.038 0.0424
Brugia malayi hypothetical protein 0.0104 0.0234 0.0272
Plasmodium falciparum metacaspase 1 0.003 0.0022 0.0024
Echinococcus multilocularis peregrin 0.0191 0.0479 0.0557
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0226 0.0577 0.1832
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trypanosoma brucei hexokinase, putative 0.1917 0.5366 0.536
Onchocerca volvulus Alhambra homolog 0.0156 0.038 0.0707
Brugia malayi Isocitrate dehydrogenase 0.0067 0.0128 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0043 0.0102
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.2185 0.2541
Brugia malayi nuclear receptor RXR 0.0026 0.0012 0.0014
Echinococcus multilocularis jumonji domain containing 1A 0.005 0.0081 0.0094
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.008 0.0165 0.016
Schistosoma mansoni helicase 0.0035 0.0038 0.0043
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0044 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0012 0.0014
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.008 0.0165 0.016
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1688 0.4716 0.4709
Brugia malayi jmjC domain containing protein 0.0199 0.0501 0.0583
Mycobacterium ulcerans hypothetical protein 0.0409 0.1097 0.1264
Loa Loa (eye worm) hypothetical protein 0.0055 0.0095 0.0111
Loa Loa (eye worm) hypothetical protein 0.0124 0.029 0.0338
Onchocerca volvulus 0.0026 0.0012 0.0023
Trypanosoma cruzi phosphomannose isomerase, putative 0.2057 0.5761 0.5752
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Brugia malayi hexokinase 0.1917 0.5366 0.6241
Plasmodium vivax SET domain protein, putative 0.0033 0.0032 0.0036
Onchocerca volvulus 0.0264 0.0685 0.1276
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0035 0.0038 0.0029
Schistosoma mansoni bromodomain containing protein 0.0045 0.0067 0.0077
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0051 0.0083 0.0071
Loa Loa (eye worm) phosphomannomutase 2 0.0265 0.0687 0.0799
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0055 0.0095 0.011
Echinococcus multilocularis hexokinase 0.1917 0.5366 0.6241
Trichomonas vaginalis phosphomannomutase, putative 0.0265 0.0687 0.0746
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0188 0.0219
Schistosoma mansoni immunophilin 0.0099 0.0219 0.0254
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0044 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0192 0.048 0.0895
Echinococcus granulosus polybromo 1 0.0035 0.0038 0.0044
Plasmodium vivax bromodomain protein, putative 0.0035 0.0038 0.0042
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0029 0.0034
Trypanosoma brucei aspartyl aminopeptidase, putative 0.008 0.0165 0.0153
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0044 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.0472 0.0549
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Echinococcus granulosus mothers against decapentaplegic 2 0.0047 0.0071 0.0083
Loa Loa (eye worm) acetyltransferase 0.0931 0.2572 0.2992
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0038 0.0016
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0041
Brugia malayi ecdysone receptor 0.0026 0.0012 0.0014
Schistosoma mansoni hypothetical protein 0.0035 0.0038 0.0043
Brugia malayi MH2 domain containing protein 0.0047 0.0071 0.0083
Entamoeba histolytica bromodomain-containing protein 0.0035 0.0038 0.0039
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.0044 0.0103
Trypanosoma brucei hexokinase 0.1917 0.5366 0.536
Leishmania major trypanothione reductase 0.0099 0.0218 0.0207
Echinococcus multilocularis polybromo 1 0.0035 0.0038 0.0044
Brugia malayi Hexokinase family protein 0.0593 0.1618 0.1882
Schistosoma mansoni hypothetical protein 0.0438 0.1177 0.1369
Onchocerca volvulus 0.0034 0.0035 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Schistosoma mansoni retinoic acid receptor RXR 0.0055 0.0095 0.011
Schistosoma mansoni hypothetical protein 0.0203 0.0512 0.0595
Schistosoma mansoni egf-like domain protein 0.0057 0.01 0.0116
Trichomonas vaginalis bromodomain containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0055 0.0095 0.0111
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0095 0.0206 0.0631
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0188 0.0219
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0226 0.0577 0.1832
Loa Loa (eye worm) hypothetical protein 0.0095 0.0206 0.024
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.2057 0.5761 0.6696
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0157 0.0383 0.0432
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0025
Brugia malayi bromodomain containing protein 0.0035 0.0038 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0 0.0001
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1688 0.4716 0.5485
Trypanosoma brucei AAA ATPase, putative 0.0035 0.0038 0.0026
Giardia lamblia Pyruvate kinase 0.0037 0.0043 0.0009
Toxoplasma gondii macrophage migration inhibitory factor, putative 0.2391 0.6707 0.7497
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Mycobacterium tuberculosis Probable aminopeptidase PepC 0.008 0.0165 0.0495
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0052 0.0084 0.0098
Trichomonas vaginalis hypothetical protein 0.0035 0.0038 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.0515 0.1395 0.1623
Trypanosoma cruzi transcription factor btf3, putative 0.0039 0.0048 0.0027
Echinococcus multilocularis neuropeptide s receptor 0.0515 0.1395 0.1623
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0158 0.0152
Mycobacterium tuberculosis Probable oxidoreductase 0.0251 0.0648 0.2063
Echinococcus granulosus tissue type plasminogen activator 0.0111 0.0252 0.0293
Brugia malayi 6-phosphofructokinase 0.0581 0.1583 0.1842
Trypanosoma brucei metacaspase 5, putative 0.003 0.0022 0.001
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0098 0.0215 0.0236
Echinococcus multilocularis Mastin 0.0052 0.0084 0.0098
Loa Loa (eye worm) hypothetical protein 0.0088 0.0188 0.0219
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0188 0.0219
Loa Loa (eye worm) hypothetical protein 0.061 0.1664 0.1935
Plasmodium falciparum M18 aspartyl aminopeptidase 0.008 0.0165 0.0183
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0043 0.0051
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.003 0.0022 0.0026
Echinococcus granulosus laminin 0.0057 0.01 0.0116
Echinococcus multilocularis fibrillin 1 0.0057 0.01 0.0116
Loa Loa (eye worm) hypothetical protein 0.0192 0.048 0.0559
Brugia malayi TAZ zinc finger family protein 0.0035 0.0038 0.0044
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0098
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.1014 0.2808 0.2792
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0052 0.0084 0.0097
Onchocerca volvulus 0.1435 0.4001 0.7456
Echinococcus multilocularis diphosphomevalonate decarboxylase 0.0046 0.0068 0.0079
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni mannose-6-phosphate isomerase 0.2057 0.5761 0.6701
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0043 0.0022
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.005 0.0081 0.0059
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Leishmania major hypothetical protein, conserved 0.0162 0.0396 0.0384
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0057 0.01 0.0116
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0037 0.0044 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Schistosoma mansoni jumonji/arid domain-containing protein 0.0199 0.0501 0.0583
Brugia malayi hypothetical protein 0.0029 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.008 0.0165 0.0191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0035 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Brugia malayi TAR-binding protein 0.0814 0.2243 0.2609
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.013 0.015
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0081 0.0094
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0157 0.0383 0.039
Echinococcus multilocularis PHD finger protein rhinoceros 0.0156 0.038 0.0441
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0192 0.0482 0.0561
Echinococcus granulosus citrate lyase subunit beta protein 0.0409 0.1097 0.1276
Brugia malayi Calcitonin receptor-like protein seb-1 0.064 0.175 0.2036
Echinococcus granulosus phosphomannomutase 0.0265 0.0687 0.0799
Plasmodium falciparum histone acetyltransferase GCN5 0.0247 0.0639 0.0714
Trichomonas vaginalis glutaminase, putative 0.2861 0.8038 0.8986
Echinococcus multilocularis smad 0.0105 0.0235 0.0274
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0127 0.0297 0.0925
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Schistosoma mansoni jumonji domain containing protein 0.005 0.0081 0.0093
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0067 0.0128 0.0116
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.0472 0.055
Loa Loa (eye worm) macrophage migration inhibitory factor 0.2391 0.6707 0.7802
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0035 0.0038 0.0026
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0067 0.0128 0.0377
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.3059 0.8597 0.8594
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Entamoeba histolytica hypothetical protein 0.0117 0.0269 0.0385
Loa Loa (eye worm) hypothetical protein 0.0206 0.0521 0.0606
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0037 0.0044 0.0037
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0044 0.0103
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0035 0.0038 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Plasmodium vivax metacaspase 1, putative 0.003 0.0022 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0044 0.0051
Plasmodium vivax bromodomain protein, putative 0.0035 0.0038 0.0042
Echinococcus granulosus ecdysone induced protein 78C 0.0055 0.0095 0.0111
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Schistosoma mansoni phosphatidylserine receptor 0.005 0.0081 0.0093
Echinococcus granulosus RUN 0.0022 0 0.0001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0095 0.0206 0.0226
Schistosoma mansoni lipoxygenase 0.0061 0.0112 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Echinococcus granulosus tar DNA binding protein 0.0814 0.2243 0.2609
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0157 0.0383 0.0404
Trypanosoma cruzi ISWI complex protein 0.0082 0.017 0.0148
Leishmania major phosphomannomutase, putative 0.0265 0.0687 0.0676
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Echinococcus granulosus peregrin 0.0191 0.0479 0.0557
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Echinococcus multilocularis chromobox protein 1 0.0078 0.0158 0.0184
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Echinococcus multilocularis L aminoadipate semialdehyde 0.0093 0.02 0.0233
Loa Loa (eye worm) hypothetical protein 0.0156 0.038 0.0441
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0055 0.0095 0.0111
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.1998 0.5594 0.6501
Trypanosoma cruzi 6-phosphogluconolactonase, putative 0.0122 0.0284 0.0262
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.0044 0.0103
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Schistosoma mansoni cercarial elastase (S01 family) 0.0052 0.0084 0.0097
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.011 0.0251 0.0292
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0215 0.0193
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0081 0.0094
Brugia malayi F/Y-rich N-terminus family protein 0.0062 0.0115 0.0134
Onchocerca volvulus 0.0046 0.0068 0.0127
Trypanosoma cruzi glucosamine-6-phosphate isomerase, putative 0.0122 0.0284 0.0262
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.013 0.0137
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0038 0.0047 0.0054
Plasmodium falciparum bromodomain protein 2, putative 0.0035 0.0038 0.0042
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0251 0.0648 0.2063
Giardia lamblia Fructose-bisphosphate aldolase 0.0325 0.0859 0.0925
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.0044 0.0103
Echinococcus granulosus CREB binding protein 0.0035 0.0038 0.0044
Trichomonas vaginalis bromodomain-containing protein, putative 0.0283 0.0738 0.0803
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0044 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0044 0.0048
Loa Loa (eye worm) TAR-binding protein 0.0814 0.2243 0.2609
Brugia malayi Trypsin family protein 0.0052 0.0084 0.0098
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0055 0.0095 0.0111
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0041
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0035 0.0023
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0095 0.0111
Toxoplasma gondii thioredoxin reductase 0.0099 0.0218 0.0231
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.064 0.175 0.2036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.0472 0.055
Schistosoma mansoni serine/threonine protein kinase 0.1688 0.4716 0.5485
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0159 0.0388 0.122
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0931 0.2572 0.2992
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.009 0.0192 0.0583
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.013 0.0137
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0044 0.0103
Plasmodium falciparum ataxin-2 like protein, putative 0.0162 0.0396 0.0442
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0095 0.0111
Onchocerca volvulus 0.0042 0.0056 0.0104
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Leishmania major macrophage migration inhibitory factor-like protein 0.2391 0.6707 0.6704
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.0594 0.0691
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0021 0.0024
Brugia malayi Pre-SET motif family protein 0.0232 0.0594 0.0691
Loa Loa (eye worm) transcription factor SMAD2 0.154 0.4296 0.4997
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0325 0.0859 0.0938
Onchocerca volvulus 0.0026 0.0012 0.0023
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0942 0.2604 0.3872
Plasmodium vivax macrophage migration inhibitory factor, putative 0.2391 0.6707 0.75
Echinococcus granulosus histone acetyltransferase KAT2B 0.0892 0.2464 0.2866
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Plasmodium vivax hexokinase, putative 0.1917 0.5366 0.6
Trichomonas vaginalis phosphofructokinase, putative 0.0581 0.1583 0.175
Brugia malayi PHD-finger family protein 0.0156 0.0379 0.0441
Echinococcus multilocularis 6 phosphogluconolactonase 0.0122 0.0284 0.033
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0012 0.0014
Leishmania major hypothetical protein, conserved 0.0111 0.0252 0.024
Schistosoma mansoni nuclear receptor 0.0026 0.0012 0.0014
Schistosoma mansoni phd finger protein 0.0035 0.0038 0.0043
Brugia malayi chromobox protein homolog 3 0.0043 0.0061 0.0071
Schistosoma mansoni coup transcription factor 0.0055 0.0095 0.011
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0038 0.0047 0.0055
Plasmodium falciparum bromodomain protein, putative 0.0035 0.0038 0.0042
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0342 0.0905 0.1053
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0043 0.0037
Entamoeba histolytica acyl-CoA synthetase, putative 0.0127 0.0297 0.0426
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0035 0.0039
Echinococcus multilocularis expressed conserved protein 0.0193 0.0486 0.0565
Schistosoma mansoni hypothetical protein 0.0085 0.0179 0.0208
Loa Loa (eye worm) hypothetical protein 0.0084 0.0177 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.051 0.1383 0.1609
Toxoplasma gondii bromodomain-containing protein 0.0035 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0127 0.0297 0.0346
Brugia malayi nuclear hormone receptor 0.0055 0.0095 0.0111
Loa Loa (eye worm) hypothetical protein 0.0045 0.0067 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Treponema pallidum fructose-bisphosphate aldolase 0.0325 0.0859 0.0987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0055 0.0095 0.0111
Leishmania major 6-phosphogluconolactonase 0.0122 0.0284 0.0272
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0055 0.0095 0.011
Loa Loa (eye worm) doublecortin family protein 0.0022 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0044 0.0051
Onchocerca volvulus Putative phosphomannomutase 0.0265 0.0687 0.1281
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0044 0.0037
Echinococcus granulosus 6 phosphogluconolactonase 0.0122 0.0284 0.033
Brugia malayi Aspartyl aminopeptidase 0.008 0.0165 0.0191
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0012 0.0014
Entamoeba histolytica hypothetical protein 0.0039 0.0048 0.0055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0117 0.0269 0.0313
Plasmodium falciparum glutathione reductase 0.0034 0.0035 0.0039
Mycobacterium tuberculosis Probable reductase 0.0226 0.0577 0.1832
Onchocerca volvulus Bile acid receptor homolog 0.0055 0.0095 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.008 0.0165 0.0191
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0044 0.0032
Toxoplasma gondii isocitrate dehydrogenase 0.0067 0.0128 0.013
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.3059 0.8597 1
Echinococcus granulosus zinc finger protein 0.0127 0.0298 0.0347
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.0012 0.0013
Schistosoma mansoni kinase 0.0858 0.2366 0.2752
Loa Loa (eye worm) hypothetical protein 0.0095 0.0206 0.024
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0095 0.0111
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0057 0.01 0.0116
Trypanosoma brucei Bromodomain factor 1 0.0035 0.0038 0.0026
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.3059 0.8597 1
Brugia malayi tailless protein 0.0026 0.0012 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0055 0.0095 0.0111
Entamoeba histolytica hypothetical protein 0.0117 0.0269 0.0385
Brugia malayi AF-10 protein 0.0051 0.0083 0.0096
Schistosoma mansoni smad1 5 8 and 0.0105 0.0235 0.0273
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0035 0.0038 0.0044
Loa Loa (eye worm) DR-78 0.0026 0.0012 0.0014
Loa Loa (eye worm) bromodomain containing protein 0.0117 0.0269 0.0313
Echinococcus multilocularis protein dispatched 1 0.0101 0.0224 0.026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0199 0.0501 0.0583
Brugia malayi translation initiation factor 4E 0.0038 0.0047 0.0055
Trypanosoma cruzi hexokinase, putative 0.1917 0.5366 0.5355
Brugia malayi jmjC domain containing protein 0.005 0.0081 0.0094
Brugia malayi Fibulin-1 precursor 0.0057 0.01 0.0116
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.0219 0.0255
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0203 0.0512 0.0595
Echinococcus granulosus fetal alzheimer antigen falz 0.0121 0.0279 0.0325
Loa Loa (eye worm) hypothetical protein 0.0052 0.0084 0.0098
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0055 0.0095 0.0111
Trypanosoma brucei metacaspase 0.003 0.0022 0.001
Loa Loa (eye worm) hypothetical protein 0.0057 0.01 0.0116
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0188 0.0219
Schistosoma mansoni Smad4 0.0047 0.0071 0.0082
Plasmodium vivax JmjC domain containing protein 0.005 0.0081 0.009
Trichomonas vaginalis phosphofructokinase, putative 0.0157 0.0383 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0055 0.0095 0.0111
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.2057 0.5761 0.6701
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0128 0.0149
Echinococcus multilocularis caspase 8 0.003 0.0022 0.0026
Brugia malayi Cell death protein 3 precursor 0.003 0.0022 0.0026
Toxoplasma gondii 6-phosphofructokinase 0.0157 0.0383 0.0415
Echinococcus multilocularis thioredoxin glutathione reductase 0.0099 0.0218 0.0254
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.3181 0.8943 1
Trypanosoma cruzi Bromodomain, putative 0.0035 0.0038 0.0016
Loa Loa (eye worm) nuclear factor I 0.0058 0.0103 0.0119
Brugia malayi BRM protein 0.0035 0.0038 0.0044
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0124 0.029 0.0901
Trypanosoma brucei hexokinase 0.1917 0.5366 0.536
Brugia malayi Bromodomain containing protein 0.0035 0.0038 0.0044
Schistosoma mansoni steroid hormone receptor ad4bp 0.0055 0.0095 0.011
Loa Loa (eye worm) hypothetical protein 0.0267 0.0695 0.0808
Brugia malayi Doublecortin family protein 0.0022 0 0.0001
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0043 0.0031
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0012 0.0014
Echinococcus multilocularis lysine specific demethylase 5A 0.0189 0.0472 0.0549
Brugia malayi AMP-binding enzyme family protein 0.0127 0.0297 0.0346
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0098 0.0215 0.025
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.3059 0.8597 1
Brugia malayi MH2 domain containing protein 0.0105 0.0235 0.0274
Schistosoma mansoni smad1 5 8 and 0.0105 0.0235 0.0273
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.011 0.0251 0.0292
Plasmodium vivax thioredoxin reductase, putative 0.0099 0.0218 0.0244
Brugia malayi 6-phosphofructokinase 0.0581 0.1583 0.1842
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0091 0.0196 0.0228
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0086 0.01
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0128 0.0149
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.013 0.0151
Echinococcus granulosus aspartyl aminopeptidase 0.008 0.0165 0.0191
Plasmodium vivax hypothetical protein, conserved 0.003 0.0022 0.0024
Echinococcus multilocularis bromodomain containing protein 8 0.0035 0.0038 0.0044
Loa Loa (eye worm) hypothetical protein 0.005 0.0081 0.0094
Echinococcus multilocularis tar DNA binding protein 0.0814 0.2243 0.2609
Schistosoma mansoni caspase-7 (C14 family) 0.011 0.0251 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0095 0.0111
Echinococcus granulosus 6 phosphofructokinase 0.0581 0.1583 0.1842
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.0084 0.0098
Schistosoma mansoni phosphomannomutase 0.0265 0.0687 0.0799
Leishmania major ATP-dependent phosphofructokinase 0.0581 0.1583 0.1573
Echinococcus granulosus caspase 0.011 0.0251 0.0292
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0035 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0055 0.0095 0.0111
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0071 0.0132
Schistosoma mansoni hypothetical protein 0.0072 0.0143 0.0166
Schistosoma mansoni zinc finger protein 0.0026 0.0012 0.0014
Echinococcus multilocularis 0.0035 0.0038 0.0044
Schistosoma mansoni smad1 5 8 and 0.0105 0.0235 0.0273
Brugia malayi phosphomannomutase 2 0.0265 0.0687 0.0799
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0055 0.0095 0.0111
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.0472 0.055
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.1688 0.4716 0.5262
Giardia lamblia Macrophage migration inhibitory factor 0.2391 0.6707 0.7491
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0038 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.0156 0.038 0.0412
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.003 0.0022 0.0011
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0035 0.0038 0.0018
Entamoeba histolytica aminopeptidase, putative 0.008 0.0165 0.0228
Trypanosoma cruzi ISWI complex protein 0.0082 0.017 0.0148
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0012 0.0014
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0035 0.0027
Brugia malayi glutathione reductase 0.0099 0.0218 0.0254
Schistosoma mansoni chromobox protein 0.0078 0.0158 0.0183
Echinococcus granulosus bromodomain containing protein 8 0.0035 0.0038 0.0044
Loa Loa (eye worm) oxidoreductase 0.0037 0.0044 0.0051
Loa Loa (eye worm) hypothetical protein 0.0035 0.0038 0.0044
Brugia malayi MH1 domain containing protein 0.0058 0.0103 0.0119
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0111 0.0252 0.0281
Echinococcus multilocularis transcription factor btf3 0.0039 0.0048 0.0056
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0226 0.0577 0.1832
Echinococcus multilocularis laminin 0.0057 0.01 0.0116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0127 0.0297 0.0925
Leishmania major macrophage migration inhibitory factor-like protein 0.2391 0.6707 0.6704
Trichomonas vaginalis bromodomain-containing protein, putative 0.0035 0.0038 0.0018

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.6 uM Binding affinity to FKBP51 (unknown origin) by competitive fluorescence polarization assay ChEMBL. 26419422
Ki (binding) = 0.9 uM Binding affinity to FKBP12 (unknown origin) by competitive fluorescence polarization assay ChEMBL. 26419422
Ki (binding) > 500 uM Binding affinity to FKBP52 (unknown origin) by competitive fluorescence polarization assay ChEMBL. 26419422

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.