Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | mitochondrial DNA polymerase beta | 0.0292 | 0.1724 | 0.5664 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0052 | 0.0152 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0035 | 0.0118 | 0.0307 |
Trypanosoma cruzi | phosphatidylinositol (3,5) kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0021 | 0.0032 | 0.0062 |
Echinococcus granulosus | GPCR family 2 | 0.0069 | 0.0329 | 0.0324 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0062 | 0.0285 | 0.2456 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0035 | 0.0118 | 0.0307 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0196 | 0.1123 | 0.3231 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0026 | 0.0062 | 0.0062 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0107 | 0.0107 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.1724 | 0.5664 |
Giardia lamblia | DINP protein human, muc B family | 0.0042 | 0.016 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0054 | 0.0238 | 0.0238 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase type II beta, putative | 0.0026 | 0.0062 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0118 | 0.0307 |
Echinococcus multilocularis | geminin | 0.0164 | 0.0923 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0134 | 0.0352 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0021 | 0.0032 | 0.0062 |
Brugia malayi | Augmenter of liver regeneration | 0.0034 | 0.0114 | 0.0294 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0023 | 0.0044 | 0.0282 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0062 | 0.0285 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0238 | 0.0654 |
Echinococcus multilocularis | GPCR, family 2 | 0.0069 | 0.0329 | 0.0324 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0146 | 0.1196 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.0044 | 0.0091 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0035 | 0.0115 | 0.0297 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0052 | 0.0129 |
Loa Loa (eye worm) | FYVE finger-containing phosphoinositide kinase | 0.0026 | 0.0062 | 0.0143 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0052 | 0.0129 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Entamoeba histolytica | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0444 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0028 | 0.0074 | 0.0069 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0035 | 0.0118 | 0.0307 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0073 | 0.0352 | 0.1124 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0073 | 0.0352 | 0.3059 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.0762 | 0.2481 |
Trypanosoma cruzi | phosphatidylinositol 4-phosphate 5-kinase alpha, putative | 0.0026 | 0.0062 | 0.0163 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.083 | 0.2378 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.0114 | 0.0357 |
Brugia malayi | Pip kinase protein 1 | 0.0026 | 0.0062 | 0.0143 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0054 | 0.0238 | 0.0766 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0052 | 0.0152 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0352 | 0.0988 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0107 | 0.0275 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0175 | 0.0175 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0501 | 0.3035 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0092 | 0.0261 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.024 | 0.1403 | 0.1403 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | unspecified product | 0.0055 | 0.0244 | 0.0765 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0013 | 0.0013 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0107 | 0.0313 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0035 | 0.0118 | 0.035 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | helicase, putative | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0039 | 0.0142 | 0.0137 |
Brugia malayi | hypothetical protein | 0.0229 | 0.133 | 0.3834 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0238 | 0.0654 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0501 | 0.3035 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0669 | 0.4084 | 0.408 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0501 | 0.3035 | 0.3035 |
Brugia malayi | Pip kinase protein 2 | 0.0326 | 0.1938 | 0.5602 |
Brugia malayi | Inositol-1 | 0.004 | 0.0146 | 0.0386 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0146 | 0.014 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0052 | 0.0152 |
Mycobacterium ulcerans | pyruvate kinase | 0.0033 | 0.0107 | 0.0313 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0033 | 0.0107 | 0.0313 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0193 | 0.0618 |
Giardia lamblia | Pyruvate kinase | 0.0033 | 0.0107 | 0.6593 |
Echinococcus granulosus | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0026 | 0.0062 | 0.0056 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0196 | 0.1123 | 0.1118 |
Echinococcus granulosus | dna polymerase eta | 0.0035 | 0.0118 | 0.0113 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0052 | 0.0129 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0107 | 0.0313 |
Brugia malayi | AMP-binding enzyme family protein | 0.0073 | 0.0352 | 0.0988 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0021 | 0.0032 | 0.0086 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0054 | 0.0238 | 0.0744 |
Brugia malayi | FYVE finger-containing phosphoinositide kinase, putative | 0.0026 | 0.0062 | 0.0143 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0052 | 0.0129 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0073 | 0.0352 | 0.1124 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0114 | 0.0334 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0146 | 0.0439 |
Onchocerca volvulus | 0.0429 | 0.2585 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0175 | 0.0169 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0196 | 0.1123 | 0.1118 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0032 | 0.0055 |
Schistosoma mansoni | cpg binding protein | 0.0113 | 0.0608 | 0.0608 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0028 | 0.0074 | 0.0074 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0052 | 0.0113 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0073 | 0.0352 | 0.3059 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0092 | 0.0261 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0032 | 0.017 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0107 | 0.0102 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0069 | 0.0329 | 0.0324 |
Schistosoma mansoni | DNA polymerase eta | 0.0035 | 0.0118 | 0.0118 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0073 | 0.0352 | 0.1124 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0073 | 0.0352 | 0.1124 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0044 | 0.0091 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0.012 | 0.0293 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0062 | 0.0285 | 0.2456 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0146 | 0.0439 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0029 | 0.0079 | 0.0074 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0028 | 0.0074 | 0.0069 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0021 | 0.0032 | 0.0062 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate-5-kinaseputativ e | 0.0026 | 0.0062 | 0.0062 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0155 | 0.0471 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0013 | 0.0013 |
Echinococcus multilocularis | pyruvate kinase | 0.0026 | 0.0063 | 0.0058 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0146 | 0.014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Schistosoma mansoni | lozenge | 0.0054 | 0.0235 | 0.0235 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0054 | 0.0238 | 0.0766 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0501 | 0.3035 | 0.8794 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-kinase | 0.0026 | 0.0062 | 0.0186 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0352 | 0.1124 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0218 | 0.1261 | 0.3633 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0501 | 0.3035 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0107 | 0.0102 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0107 | 0.0296 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0086 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0035 | 0.0118 | 0.035 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.0114 | 0.0108 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0052 | 0.0113 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0024 | 0.005 | 0.005 |
Leishmania major | DNA polymerase eta, putative | 0.0035 | 0.0118 | 0.035 |
Brugia malayi | sulfakinin receptor protein | 0.0229 | 0.133 | 0.3834 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.083 | 0.083 |
Echinococcus multilocularis | cpg binding protein | 0.012 | 0.0648 | 0.0643 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0073 | 0.0352 | 0.1124 |
Leishmania major | phosphatidylinositol (3,5) kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Echinococcus granulosus | phosphatidylinositol phosphate 5 kinase type III | 0.0026 | 0.0062 | 0.0056 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0138 | 0.0762 | 0.2481 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0292 | 0.1724 | 0.5664 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0032 | 0.0055 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0146 | 0.0146 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0501 | 0.3035 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0069 | 0.0329 | 0.0922 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0026 | 0.0062 | 0.0163 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0018 | 0.0008 | 0.0008 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0501 | 0.3035 | 1 |
Loa Loa (eye worm) | FYVE zinc finger family protein | 0.0026 | 0.0062 | 0.0143 |
Brugia malayi | polk-prov protein | 0.0038 | 0.0134 | 0.0352 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Loa Loa (eye worm) | histone methyltransferase | 0.0035 | 0.0118 | 0.0306 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Echinococcus multilocularis | Protein lozenge | 0.0054 | 0.0235 | 0.023 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0033 | 0.0107 | 0.0336 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0107 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.2585 | 0.7484 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0021 | 0.0032 | 0.0062 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0035 | 0.0118 | 0.0118 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0021 | 0.0032 | 0.017 |
Giardia lamblia | Phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.3657 |
Onchocerca volvulus | 0.0113 | 0.0608 | 0.2256 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0026 | 0.0062 | 0.0163 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0024 | 0.005 | 0.0045 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0501 | 0.3035 | 1 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.0114 | 0.0357 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0039 | 0.0142 | 0.0137 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0146 | 0.0439 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0154 | 0.086 | 0.2804 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0024 | 0.005 | 0.0045 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0021 | 0.0032 | 0.0062 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0215 | 0.1242 | 0.4082 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0073 | 0.0352 | 0.1068 |
Echinococcus multilocularis | NMDA receptor | 0.0039 | 0.0142 | 0.0137 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.012 | 0.0354 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1614 | 1 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0021 | 0.0032 | 0.0062 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0024 | 0.005 | 0.011 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0024 | 0.005 | 0.011 |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0026 | 0.0062 | 0.0163 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.0114 | 0.0334 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0501 | 0.3035 | 1 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0062 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0024 | 0.005 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.1614 | 1 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0146 | 0.1196 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0033 | 0.0107 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0329 | 0.0922 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.0114 | 0.0334 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.0114 | 0.0357 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0013 | 0.0024 |
Plasmodium vivax | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0186 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Echinococcus multilocularis | dna polymerase kappa | 0.0062 | 0.0285 | 0.028 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0028 | 0.0074 | 0.0069 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0155 | 0.0471 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.0062 | 0.0186 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0069 | 0.0329 | 0.0922 |
Trypanosoma brucei | phosphatidylinositol phosphate kinase alpha | 0.0026 | 0.0062 | 0.0163 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0029 | 0.0079 | 0.0079 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0035 | 0.0118 | 0.0113 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.0114 | 0.0334 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0501 | 0.3035 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0146 | 0.0462 |
Echinococcus multilocularis | phosphatidylinositol phosphate 5 kinase type III | 0.0026 | 0.0062 | 0.0056 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0013 | 0.0465 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0021 | 0.0032 | 0.0062 |
Loa Loa (eye worm) | oxidoreductase | 0.0021 | 0.0032 | 0.0055 |
Loa Loa (eye worm) | pip kinase 2 | 0.0326 | 0.1938 | 0.5602 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0329 | 0.0329 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0138 | 0.0762 | 0.2481 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0032 | 0.017 |
Schistosoma mansoni | glutamate receptor kainate | 0.0024 | 0.005 | 0.005 |
Echinococcus granulosus | geminin | 0.0164 | 0.0923 | 0.0918 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Trypanosoma brucei | phosphatidylinositol (3,5) kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0175 | 0.0175 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0013 | 0.0024 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0013 | 0.5 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0013 | 0.0007 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0033 | 0.0107 | 0.0275 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0069 | 0.0329 | 0.0324 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0175 | 0.0169 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0326 | 0.1938 | 0.1938 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0069 | 0.0329 | 0.0922 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0419 | 0.2517 | 0.2513 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0021 | 0.0032 | 0.0026 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0155 | 0.0471 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0107 | 0.0296 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0042 | 0.016 | 0.0487 |
Schistosoma mansoni | pyruvate kinase | 0.0017 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0107 | 0.0275 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0035 | 0.0118 | 0.0113 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Echinococcus granulosus | dna polymerase kappa | 0.0062 | 0.0285 | 0.028 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0669 | 0.4084 | 0.4084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0175 | 0.0175 |
Leishmania major | phosphatidylinositol-4-phosphate-5-kinase-likep ro tein | 0.0026 | 0.0062 | 0.0163 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0024 | 0.005 | 0.0045 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0175 | 0.0472 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0149 | 0.083 | 0.2378 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0175 | 0.0169 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0073 | 0.0352 | 0.1124 |
Echinococcus granulosus | glutamate receptor 2 | 0.002 | 0.0023 | 0.0017 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0042 | 0.016 | 0.0487 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.016 | 0.0487 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0219 | 0.0683 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0028 | 0.0074 | 0.0069 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0146 | 0.1196 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Onchocerca volvulus | 0.0326 | 0.1938 | 0.7466 | |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like protein | 0.0026 | 0.0062 | 0.0163 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0352 | 0.0988 |
Plasmodium vivax | pyruvate kinase, putative | 0.0033 | 0.0107 | 0.0336 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0923 | 0.0923 |
Brugia malayi | AMP-binding enzyme family protein | 0.0073 | 0.0352 | 0.0988 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0062 | 0.0285 | 0.0902 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0107 | 0.0275 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0026 | 0.0062 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0107 | 0.0275 |
Echinococcus multilocularis | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0026 | 0.0062 | 0.0056 |
Brugia malayi | CXXC zinc finger family protein | 0.0113 | 0.0608 | 0.1731 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0021 | 0.0032 | 0.0062 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.0114 | 0.0108 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0035 | 0.0118 | 0.0112 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0329 | 0.0329 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0062 | 0.0285 | 0.0902 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0326 | 0.1938 | 0.1933 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0326 | 0.1938 | 0.1938 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0033 | 0.0107 | 0.0252 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0013 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0238 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0238 | 0.0654 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0021 | 0.0032 | 0.0055 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0029 | 0.0079 | 0.0074 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0021 | 0.0032 | 0.0055 |
Giardia lamblia | Hypothetical protein | 0.0026 | 0.0062 | 0.3657 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0329 | 0.0329 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0073 | 0.0352 | 0.1124 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0073 | 0.0352 | 0.1124 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0146 | 0.0439 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0196 | 0.1123 | 0.1118 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0146 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0567 | 0.3449 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0035 | 0.0118 | 0.0112 |
Echinococcus granulosus | cpg binding protein | 0.012 | 0.0648 | 0.0643 |
Loa Loa (eye worm) | pip kinase 1 | 0.0026 | 0.0062 | 0.0143 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0032 | 0.0062 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0146 | 0.1196 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0501 | 0.3035 | 1 |
Plasmodium falciparum | phosphatidylinositol-4-phosphate 5-kinase | 0.0026 | 0.0062 | 0.0186 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0018 | 0.0013 | 0.0001 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0501 | 0.3035 | 0.8794 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0419 | 0.2517 | 0.2513 |
Schistosoma mansoni | cpg binding protein | 0.012 | 0.0648 | 0.0648 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0146 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0238 | 0.0654 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0054 | 0.0238 | 0.0744 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0035 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.2585 | 0.7484 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0107 | 0.0313 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0146 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0352 | 0.0988 |
Onchocerca volvulus | 0.0073 | 0.0352 | 0.1256 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0032 | 0.0062 |
Schistosoma mansoni | glutamate receptor kainate | 0.0054 | 0.0238 | 0.0238 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0035 | 0.0118 | 0.0952 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.1938 | 0.5602 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0073 | 0.0352 | 0.1124 |
Entamoeba histolytica | phosphoinositide kinase, putative | 0.0026 | 0.0062 | 0.0444 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0024 | 0.005 | 0.005 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0107 | 0.0107 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0292 | 0.1724 | 0.5664 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0175 | 0.0472 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0013 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0923 | 0.0923 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0026 | 0.0062 | 0.0444 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0033 | 0.0107 | 0.0313 |
Toxoplasma gondii | propionate-CoA ligase | 0.0021 | 0.0032 | 0.0086 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0219 | 0.0683 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0092 | 0.0261 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0113 | 0.0608 | 0.1731 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0021 | 0.0032 | 0.0062 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0059 | 0.0267 | 0.0261 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0175 | 0.0169 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0107 | 0.0102 |
Brugia malayi | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0026 | 0.0062 | 0.0062 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Echinococcus granulosus | glutamate receptor 2 | 0.0029 | 0.0079 | 0.0074 |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0326 | 0.1938 | 0.1933 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0021 | 0.0032 | 0.0026 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0062 | 0.0285 | 0.0902 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0024 | 0.005 | 0.011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0059 | 0.0417 |
Trypanosoma brucei | unspecified product | 0.0024 | 0.005 | 0.0124 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0073 | 0.0352 | 0.3059 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0034 | 0.0114 | 0.0294 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0669 | 0.4084 | 0.408 |
Echinococcus multilocularis | dna polymerase eta | 0.0035 | 0.0118 | 0.0113 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0062 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0032 | 0.0055 |
Mycobacterium ulcerans | hypothetical protein | 0.0154 | 0.086 | 0.2804 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.133 | 0.3834 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0024 | 0.005 | 0.005 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0107 | 0.0296 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0073 | 0.0352 | 0.1124 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0073 | 0.0352 | 0.1068 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0107 | 0.0852 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0501 | 0.3035 | 1 |
Schistosoma mansoni | cpg binding protein | 0.012 | 0.0648 | 0.0648 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0155 | 0.0471 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0134 | 0.04 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0021 | 0.0032 | 0.0086 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0196 | 0.1123 | 0.1118 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0054 | 0.0238 | 1 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0086 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.0114 | 0.0357 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0026 | 0.0062 | 0.0444 |
Brugia malayi | AMP-binding enzyme family protein | 0.0073 | 0.0352 | 0.0988 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0039 | 0.0142 | 0.0137 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0329 | 0.0329 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0218 | 0.1261 | 0.3633 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0059 | 0.0417 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0107 | 0.0852 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0052 | 0.0152 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0035 | 0.0118 | 0.035 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0026 | 0.0062 | 0.0186 |
Brugia malayi | hypothetical protein | 0.0429 | 0.2585 | 0.7484 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0107 | 0.0313 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0219 | 0.0683 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type I | 0.0026 | 0.0062 | 0.0062 |
Echinococcus multilocularis | glutamate receptor 2 | 0.002 | 0.0023 | 0.0017 |
Plasmodium falciparum | pyruvate kinase | 0.0033 | 0.0107 | 0.0336 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0073 | 0.0352 | 0.1124 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0134 | 0.04 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0211 | 0.0657 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0032 | 0.0062 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0062 | 0.0285 | 0.0902 |
Leishmania major | dihydroorotate dehydrogenase | 0.0501 | 0.3035 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0073 | 0.0352 | 0.1124 |
Leishmania major | DNA polymerase kappa, putative | 0.0042 | 0.016 | 0.0487 |
Trypanosoma brucei | unspecified product | 0.0024 | 0.005 | 0.0124 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.0114 | 0.0334 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0024 | 0.005 | 0.011 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0055 | 0.0244 | 0.0765 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0029 | 0.0079 | 0.0074 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0219 | 0.0683 |
Loa Loa (eye worm) | runx1 | 0.0054 | 0.0235 | 0.0648 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0196 | 0.1123 | 0.3674 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0039 | 0.0142 | 0.0137 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0026 | 0.0062 | 0.0163 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0021 | 0.0032 | 0.0032 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0567 | 0.3449 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0021 | 0.0032 | 0.0062 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0501 | 0.3035 | 1 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0196 | 0.1123 | 1 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0033 | 0.0107 | 0.0313 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Survivors (functional) | = 3 | Antitumor activity was assessed against TLX5 tumors in CBA/CA mouse by inoculation of 2 x 10e5 tumor cells through sc route and number of survivors was reported at 40 mg/kg ip dose; 3/5 | ChEMBL. | 3806616 |
Survivors (functional) | = 3 | Antitumor activity was assessed against TLX5 tumors in CBA/CA mouse by inoculation of 2 x 10e5 tumor cells through sc route and number of survivors was reported at 20 mg/kg ip dose; 3/5 | ChEMBL. | 3806616 |
Survivors (functional) | = 7 | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and number of Survivors to duration was reported at 40 mg/kg po dose; 7/7 | ChEMBL. | 3806616 |
T/C (functional) | = 68 % | Antitumor activity was assessed against TLX5 tumors in CBA/CA mouse by inoculation of 2 x 10e5 tumor cells through sc route and mean death of animals (treated/control) was reported at 80 mg/kg dose | ChEMBL. | 3806616 |
T/C (functional) | = 152 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 10 mg/kg po dose | ChEMBL. | 3806616 |
T/C (functional) | = 152 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 10 mg/kg po dose | ChEMBL. | 3806616 |
T/C (functional) | = 222 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 20 mg/kg po dose | ChEMBL. | 3806616 |
T/C (functional) | = 222 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 20 mg/kg po dose | ChEMBL. | 3806616 |
T/C (functional) | > 381 % | Antitumor activity was assessed against TLX5 tumors in CBA/CA mouse by inoculation of 2 x 10e5 tumor cells through sc route and mean death of animals (treated/control) was reported at 40 mg/kg dose | ChEMBL. | 3806616 |
T/C (functional) | > 385 % | Antitumor activity was assessed against TLX5 tumors in CBA/CA mouse by inoculation of 2 x 10e5 tumor cells through sc route and mean death of animals (treated/control) was reported at 20 mg/kg dose | ChEMBL. | 3806616 |
T/C (functional) | > 750 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 40 mg/kg po dose | ChEMBL. | 3806616 |
T/C (functional) | > 750 % | Antitumor activity was assessed against L1210 tumors in B6D2F1 mouse by inoculation of 10e5 tumor cells through iv route and mean death of animals (treated/control) was reported at 40 mg/kg po dose | ChEMBL. | 3806616 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.