Detailed information for compound 211083

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 271.232 | Formula: C12H9N5O3
  • H donors: 1 H acceptors: 6 LogP: 1.45 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1cccc(c1)Cn1cnc2c1c(O)ncn2
  • InChi: 1S/C12H9N5O3/c18-12-10-11(13-6-14-12)15-7-16(10)5-8-2-1-3-9(4-8)17(19)20/h1-4,6-7H,5H2,(H,13,14,18)
  • InChiKey: LWTMMJGKVKKLMI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ATP-binding cassette transporter 0.0194 0.0566 0.0576
Echinococcus granulosus tm gpcr rhodopsin 0.0927 0.3026 0.3044
Loa Loa (eye worm) hypothetical protein 0.0179 0.0515 0.0946
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0168 0.0478 0.1288
Brugia malayi glutamate synthase 0.0263 0.0797 0.1332
Toxoplasma gondii selenide, water dikinase 0.0263 0.0797 0.155
Echinococcus granulosus alpha 1A adrenergic receptor 0.031 0.0955 0.096
Echinococcus granulosus voltage gated potassium channel 0.006 0.0116 0.0116
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0083 0.0193 0.0194
Brugia malayi calmodulin 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.026 0.0618
Schistosoma mansoni growth hormone secretagogue receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.0042 0.0057 0.0105
Brugia malayi Bromodomain containing protein 0.0087 0.0206 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0293 0.0699
Echinococcus multilocularis lamin dm0 0.0088 0.0209 0.0211
Schistosoma mansoni neuropeptide f receptor 76f 0.031 0.0955 0.0975
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0263 0.0797 0.079
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0412 0.0685
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0084 0.0198 0.0584
Mycobacterium ulcerans hypothetical protein 0.0263 0.0797 0.2441
Trichomonas vaginalis chromobox protein, putative 0.0037 0.004 0.0077
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0125 0.0123
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0302 0.0555
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0199 0.02
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0029 0.0012 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0084 0.0085
Trichomonas vaginalis calmodulin, putative 0.0029 0.0014 0.0012
Trypanosoma cruzi cytochrome P450, putative 0.0121 0.0322 0.0315
Loa Loa (eye worm) hypothetical protein 0.0222 0.0661 0.1214
Brugia malayi Transient-receptor-potential like protein 0.006 0.0116 0.0186
Plasmodium vivax multidomain scavenger receptor, putative 0.0088 0.0209 0.0392
Trichomonas vaginalis Ferredoxin 1 0.0029 0.0012 0.0008
Onchocerca volvulus Dual oxidase homolog 0.0231 0.0692 0.1684
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0084 0.0199 0.02
Toxoplasma gondii histone lysine methyltransferase SET1 0.0131 0.0354 0.0684
Entamoeba histolytica protein kinase rad3, putative 0.0036 0.0036 0.0139
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0152 0.0153
Echinococcus granulosus voltage gated hydrogen channel 1 0.006 0.0116 0.0116
Schistosoma mansoni peptide (allatostatin)-like receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0027 0.0007 0.0012
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0063 0.0149
Schistosoma mansoni chromobox protein 0.0037 0.004 0.0035
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0989 0.3235 0.6326
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0263 0.0797 0.2163
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.006 0.0116 0.0113
Echinococcus multilocularis chromobox protein 1 0.0107 0.0273 0.0275
Echinococcus granulosus potassium voltage gated channel subfamily A 0.006 0.0116 0.0116
Echinococcus multilocularis insulin receptor 0.0059 0.0114 0.0115
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0075 0.0168 0.0161
Brugia malayi Metabotropic glutamate receptor precursor. 0.0027 0.0007 0.0002
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0078 0.0176 0.0177
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0029 0.0012 0.0009
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0012 0.0005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0118 0.031 0.0313
Brugia malayi follicle stimulating hormone receptor 0.1008 0.3297 0.5541
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0513
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0125 0.0202
Leishmania major calmodulin, putative 0.0029 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Echinococcus granulosus microtubule associated protein 2 0.2928 0.9741 0.9798
Onchocerca volvulus Glucosylceramidase homolog 0.0539 0.1725 0.4227
Trypanosoma brucei C-8 sterol isomerase, putative 0.1191 0.3912 0.3906
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0171 0.0491 0.0498
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0152 0.0153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0125 0.023
Echinococcus multilocularis calmodulin 0.0029 0.0014 0.0014
Brugia malayi hypothetical protein 0.0088 0.0209 0.0343
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus tm gpcr rhodopsin 0.031 0.0955 0.096
Toxoplasma gondii FATC domain-containing protein 0.0036 0.0036 0.006
Onchocerca volvulus 0.0062 0.0125 0.0291
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0125 0.0202
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0043 0.0066
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Loa Loa (eye worm) hypothetical protein 0.0081 0.0186 0.0342
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0187 0.0543 0.0537
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0014 0.0015
Echinococcus multilocularis chromobox protein 1 0.0107 0.0273 0.0275
Loa Loa (eye worm) hypothetical protein 0.0441 0.1396 0.2563
Brugia malayi Doublecortin family protein 0.0088 0.0209 0.0343
Schistosoma mansoni hypothetical protein 0.006 0.0116 0.0113
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0014 0.0027
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.006 0.0116 0.0113
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0097 0.0242 0.0471
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0084 0.0198 0.0191
Echinococcus multilocularis 0.0084 0.0198 0.0199
Entamoeba histolytica hypothetical protein 0.0031 0.002 0.006
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0099 0.0247 0.0249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0166 0.0472 0.0466
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0039 0.0039
Echinococcus granulosus ryanodine receptor 44f 0.006 0.0116 0.0116
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0263 0.0797 0.1557
Brugia malayi Protein kinase domain containing protein 0.0162 0.0458 0.0761
Echinococcus granulosus ATP binding cassette sub family G 0.0044 0.0063 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0037 0.004 0.006
Loa Loa (eye worm) inositol-1 0.0117 0.0308 0.0566
Chlamydia trachomatis endonuclease IV 0.0168 0.0478 0.1453
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0302 0.0722
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0005 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0126 0.0232
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0084 0.0081
Schistosoma mansoni amine GPCR 0.031 0.0955 0.0975
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Echinococcus granulosus intermediate filament protein 0.0088 0.0209 0.0211
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0166 0.0472 0.0467
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0263 0.0797 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0259 0.0617
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0084 0.0198 0.0385
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0171 0.0491 0.0493
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0121 0.0337
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0167 0.0475 0.079
Echinococcus granulosus 7tm_1 domain containing protein 0.031 0.0955 0.096
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0263 0.0797 0.1939
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0059 0.0114 0.0115
Brugia malayi FAT domain containing protein 0.0028 0.0009 0.0006
Onchocerca volvulus 0.0029 0.0014 0.0019
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0014 0.0009
Echinococcus multilocularis sex peptide receptor 0.031 0.0955 0.096
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0166 0.0472 0.0464
Plasmodium vivax DNA topoisomerase II, putative 0.0167 0.0475 0.0913
Brugia malayi Cyclic-nucleotide gated cation channel 0.0084 0.0199 0.0326
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0265 0.0806 0.2471
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0263 0.0797 0.1544
Trypanosoma cruzi trypanothione reductase, putative 0.1548 0.511 0.5106
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.031 0.0955 0.096
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0099 0.0247 0.0407
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Toxoplasma gondii Erv1 / Alr family protein 0.0075 0.0168 0.0318
Mycobacterium ulcerans electron transfer protein 0.0029 0.0012 0.0009
Onchocerca volvulus 0.0441 0.1396 0.3418
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0037 0.004 0.0068
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Schistosoma mansoni hypothetical protein 0.0048 0.0076 0.0073
Echinococcus granulosus TRP transient receptor potential channel 0.006 0.0116 0.0116
Echinococcus multilocularis thioredoxin glutathione reductase 0.1548 0.511 0.514
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0084 0.0199 0.0365
Schistosoma mansoni opsin-like receptor 0.031 0.0955 0.0975
Toxoplasma gondii non-specific serine/threonine protein kinase 0.004 0.005 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0125 0.023
Echinococcus granulosus zinc finger protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0044 0.0063 0.0057
Leishmania major C-8 sterol isomerase-like protein 0.1191 0.3912 0.3908
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0143 0.0134
Echinococcus granulosus epidermal growth factor receptor 0.0098 0.0244 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Leishmania major hypothetical protein, conserved 0.0263 0.0797 0.0792
Echinococcus granulosus potassium voltage gated channel subfamily C 0.006 0.0116 0.0116
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022 0.0655 0.0659
Toxoplasma gondii calmodulin, putative 0.0029 0.0014 0.0016
Schistosoma mansoni glutamate receptor kainate 0.0193 0.0564 0.0573
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0088 0.021 0.0211
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.004 0.0077
Echinococcus multilocularis sodium leak channel non selective protein 0.006 0.0116 0.0116
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0216 0.0639 0.1173
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Schistosoma mansoni lamin 0.0088 0.0209 0.021
Echinococcus multilocularis fmrfamide receptor 0.031 0.0955 0.096
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0117 0.0308 0.0594
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0084 0.0198 0.0584
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Echinococcus multilocularis conserved hypothetical protein 0.006 0.0116 0.0116
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0039 0.0039
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0116 0.0116
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0086 0.0204 0.0205
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.019 0.0553 0.0548
Brugia malayi hypothetical protein 0.0144 0.04 0.0664
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0095
Mycobacterium ulcerans glutamate synthase subunit beta 0.0263 0.0797 0.2441
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0084 0.0198 0.0584
Schistosoma mansoni survival motor neuron protein 0.0205 0.0602 0.0613
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.031 0.0955 0.0975
Echinococcus multilocularis voltage gated hydrogen channel 1 0.006 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0016
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0027 0.0007 0.0002
Brugia malayi protein-tyrosine kinase 0.0078 0.0176 0.0287
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.002 0.0029
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0084 0.0198 0.0189
Onchocerca volvulus 0.0029 0.0012 0.0013
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0263 0.0797 0.1462
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0125 0.0202
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0139 0.0382 0.0387
Trypanosoma brucei calmodulin 0.0029 0.0014 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0199 0.0199
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Brugia malayi Cytochrome P450 family protein 0.0084 0.0198 0.0324
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Schistosoma mansoni alpha-1 adrenergic receptor 0.031 0.0955 0.0975
Schistosoma mansoni hypothetical protein 0.031 0.0955 0.0975
Echinococcus granulosus g protein coupled receptor 0.031 0.0955 0.096
Loa Loa (eye worm) hypothetical protein 0.0086 0.0204 0.0374
Echinococcus granulosus atrial natriuretic peptide receptor 0.0027 0.0007 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.031 0.0955 0.2331
Brugia malayi Probable DNA topoisomerase II 0.0167 0.0475 0.079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.031 0.0955 0.096
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0121 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0112 0.0293 0.0699
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0166 0.0472 0.0915
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0162 0.0458 0.1109
Echinococcus multilocularis sodium channel protein 0.0674 0.2179 0.2192
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0171 0.0491 0.0493
Loa Loa (eye worm) hypothetical protein 0.0031 0.0018 0.0033
Brugia malayi Serotonin receptor 0.031 0.0955 0.1598
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0175 0.0504 0.0507
Brugia malayi SET domain containing protein 0.0044 0.0064 0.0098
Echinococcus granulosus cGMP dependent protein kinase 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0263 0.0797 0.1557
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0989 0.3235 1
Loa Loa (eye worm) calcium channel 0.0171 0.0491 0.09
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0125 0.0123
Echinococcus multilocularis glutamate receptor 2 0.022 0.0655 0.0659
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1581 0.5223 0.5254
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0658 0.2125 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0036 0.0036 0.0029
Echinococcus granulosus single minded 2 0.005 0.0082 0.0083
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0029 0.0012 0.0007
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0144 0.04 0.0393
Trichomonas vaginalis Ferredoxin 6 0.0029 0.0012 0.0008
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.0198 0.0191
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0472 0.1141
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0029 0.0014 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0553 0.134
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Brugia malayi CXXC zinc finger family protein 0.0063 0.0126 0.0204
Schistosoma mansoni hypothetical protein 0.0068 0.0144 0.0143
Loa Loa (eye worm) hypothetical protein 0.0076 0.0171 0.0315
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0086 0.0204 0.0205
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.031 0.0955 0.0975
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0088 0.0194
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0156 0.0287
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0121 0.0346
Schistosoma mansoni ap endonuclease 0.0061 0.0121 0.0118
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0125 0.0123
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0084 0.0198 0.0385
Schistosoma mansoni sodium/chloride dependent transporter 0.012 0.0317 0.032
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0078 0.0176 0.0177
Echinococcus multilocularis ATP binding cassette sub family G 0.0044 0.0063 0.0064
Schistosoma mansoni glutamate synthase 0.0263 0.0797 0.0813
Brugia malayi SRC-1 0.0086 0.0204 0.0334
Echinococcus granulosus lysine specific demethylase 5A 0.0048 0.0076 0.0076
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0161 0.0162
Plasmodium falciparum phd finger protein, putative 0.0035 0.0032 0.0053
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0043 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Loa Loa (eye worm) glutamate receptor 1 0.0193 0.0564 0.1035
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0263 0.0797 0.1557
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0068 0.0068
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0044 0.0063 0.0058
Loa Loa (eye worm) SRC-1 0.0086 0.0204 0.0374
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0263 0.0797 0.155
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.002 0.0029
Schistosoma mansoni hypothetical protein 0.0102 0.0258 0.026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0117 0.0308 0.1424
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0263 0.0797 0.079
Echinococcus multilocularis transfer RNA-Gly 0.006 0.0116 0.0116
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.2561 0.8512 0.8511
Loa Loa (eye worm) hypothetical protein 0.0693 0.2241 0.4114
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0029 0.0012 0.0009
Schistosoma mansoni hypothetical protein 0.031 0.0955 0.0975
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0822 0.2674 0.4908
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0302 0.0722
Mycobacterium ulcerans dehydrogenase 0.0263 0.0797 0.2441
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0263 0.0797 0.155
Brugia malayi hypothetical protein 0.0441 0.1396 0.2341
Schistosoma mansoni calcium-activated potassium channel 0.006 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.0263 0.0797 0.1462
Brugia malayi hypothetical protein 0.0107 0.0273 0.0451
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0121 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Toxoplasma gondii DNA topoisomerase 2, putative 0.0167 0.0475 0.092
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0125 0.0123
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.031 0.0955 0.096
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0674 0.2179 0.2192
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0063 0.0122
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0014 0.0019
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Brugia malayi cation channel family protein 0.006 0.0116 0.0186
Echinococcus granulosus voltage dependent calcium channel 0.0081 0.0186 0.0188
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0212 0.0627 0.1526
Plasmodium falciparum calmodulin 0.0029 0.0014 0.0016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0045 0.0089
Brugia malayi jmjC domain containing protein 0.0114 0.0298 0.0492
Echinococcus multilocularis transient receptor potential gamma protein 0.006 0.0116 0.0116
Onchocerca volvulus 0.0209 0.0617 0.1502
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0014 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Brugia malayi hypothetical protein 0.0118 0.031 0.0513
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0084 0.0198 0.0385
Echinococcus multilocularis Polycystic kidney disease protein 0.0088 0.0209 0.0211
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0263 0.0797 0.0801
Loa Loa (eye worm) transcription factor SMAD2 0.0261 0.0791 0.1453
Brugia malayi Guanylyl cyclase protein 23 0.0035 0.0031 0.0044
Schistosoma mansoni hypothetical protein 0.0084 0.0198 0.0197
Brugia malayi hypothetical protein 0.0027 0.0007 0.0002
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0118 0.031 0.0312
Trypanosoma brucei calmodulin 0.0029 0.0014 0.0004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0084 0.0085
Mycobacterium tuberculosis Probable oxidoreductase 0.1112 0.3649 0.714
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.006 0.0116 0.0186
Echinococcus granulosus neuropeptide receptor 0.031 0.0955 0.096
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0084 0.0198 0.0584
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0099 0.0248 0.0409
Echinococcus multilocularis potassium voltage gated channel protein 0.006 0.0116 0.0116
Echinococcus granulosus cytochrome P450 2K1 0.0084 0.0198 0.0199
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0008 0.0002
Schistosoma mansoni tyrosine kinase 0.0086 0.0204 0.0204
Schistosoma mansoni hypothetical protein 0.0263 0.0797 0.0813
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0084 0.0198 0.0584
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0302 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0458 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0125 0.0202
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0121 0.0322 0.097
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0045 0.0067 0.0179
Echinococcus multilocularis G protein coupled receptor 139 0.031 0.0955 0.096
Schistosoma mansoni transient receptor potential channel 0.006 0.0116 0.0113
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.006 0.0116 0.0186
Brugia malayi hypothetical protein 0.0091 0.0222 0.0365
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0036 0.0036 0.0139
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.006 0.0116 0.0113
Loa Loa (eye worm) runx1 0.0055 0.0101 0.0186
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0989 0.3235 0.3254
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0121 0.0114
Echinococcus multilocularis L aminoadipate semialdehyde 0.0099 0.0248 0.025
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0064 0.0129 0.013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022 0.0655 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Schistosoma mansoni hypothetical protein 0.1403 0.4623 0.4743
Echinococcus granulosus calcium activated potassium channel 0.0062 0.0122 0.0123
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0038 0.0043 0.0063
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0118 0.031 0.0313
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.015 0.0419 0.0422
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0029 0.0012 0.0022
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0263 0.0797 0.0788
Echinococcus multilocularis isocitrate dehydrogenase 0.0068 0.0143 0.0144
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0144 0.0234
Echinococcus granulosus sodium leak channel non selective protein 0.006 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0031 0.0018 0.0013
Leishmania major cytochrome p450-like protein 0.0084 0.0198 0.0192
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0084 0.0198 0.0385
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0088 0.0194
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0726 0.2354 0.3952
Loa Loa (eye worm) hypothetical protein 0.0093 0.0227 0.0417
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0037 0.004 0.0068
Echinococcus multilocularis Chromo domain 0.0037 0.004 0.004
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0043 0.0061 0.0142
Echinococcus granulosus g-protein coupled receptor 0.031 0.0955 0.096
Treponema pallidum thioredoxin reductase (trxB) 0.0263 0.0797 0.2441
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Loa Loa (eye worm) glutathione reductase 0.1548 0.511 0.9379
Brugia malayi Pre-SET motif family protein 0.1088 0.3567 0.5994
Echinococcus granulosus neuropeptides capa receptor 0.031 0.0955 0.096
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0125 0.0123
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0199 0.02
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.019 0.0553 0.0547
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.0063 0.0168
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0199 0.02
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0084 0.0199 0.02
Entamoeba histolytica ABC transporter, putative 0.0044 0.0063 0.0267
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.019 0.0553 0.0563
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0038 0.0043 0.0073
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.031 0.0955 0.096
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.031 0.0955 0.096
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0989 0.3235 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0036 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0308 0.0738
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0012 0.0005
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0989 0.3235 0.3317
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Trichomonas vaginalis Ferredoxin 7 0.0029 0.0012 0.0008
Echinococcus multilocularis glutamate receptor 2 0.0193 0.0564 0.0567
Loa Loa (eye worm) hypothetical protein 0.006 0.0117 0.0215
Echinococcus granulosus potassium voltage gated channel protein 0.006 0.0116 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Onchocerca volvulus 0.031 0.0955 0.2331
Loa Loa (eye worm) hypothetical protein 0.0209 0.0617 0.1133
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0302 0.0805
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0263 0.0797 0.1332
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0039 0.0039
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Echinococcus granulosus epidermal growth factor receptor 0.018 0.052 0.0523
Echinococcus multilocularis dro:myosuppressin receptor 0.031 0.0955 0.096
Schistosoma mansoni transient receptor potential channel 0.006 0.0117 0.0115
Echinococcus granulosus ATP binding cassette sub family G 0.0044 0.0063 0.0064
Brugia malayi Protein kinase domain containing protein 0.0059 0.0114 0.0183
Onchocerca volvulus Calmodulin homolog 0.0029 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0151 0.0423 0.0414
Leishmania major hypothetical protein, unknown function 0.006 0.0116 0.011
Echinococcus granulosus adenylate cyclase 9 0.0093 0.0227 0.0229
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0109 0.028 0.0271
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0116 0.0116
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0164 0.0466 0.1126
Loa Loa (eye worm) TK protein kinase 0.0078 0.0176 0.0323
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3005 1 1
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0118 0.031 0.0312
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0158 0.0445 0.0436
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0263 0.0797 0.1939
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0263 0.0797 0.2441
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0166 0.0472 0.0467
Trichomonas vaginalis aldehyde oxidase, putative 0.0895 0.2921 0.7168
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2265 0.7516 0.7514
Entamoeba histolytica DNA topoisomerase II, putative 0.0167 0.0475 0.221
Chlamydia trachomatis glutamine binding protein 0.0045 0.0067 0.0179
Schistosoma mansoni hypothetical protein 0.031 0.0955 0.0975
Echinococcus granulosus Rac GTPase activating protein 1 0.0076 0.0171 0.0173
Onchocerca volvulus 0.0222 0.066 0.1607
Loa Loa (eye worm) G-protein coupled receptor 0.031 0.0955 0.1752
Loa Loa (eye worm) hypothetical protein 0.0803 0.2612 0.4794
Schistosoma mansoni lozenge 0.0055 0.0101 0.0099
Schistosoma mansoni hypothetical protein 0.0088 0.021 0.021
Schistosoma mansoni microtubule-associated protein tau 0.2928 0.9741 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0068 0.0143 0.0269
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.006 0.0116 0.0186
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.031 0.0955 0.096
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0116
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0171 0.0491 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0125 0.0202
Echinococcus multilocularis lysine specific demethylase 5A 0.0042 0.0057 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0205 0.0602 0.1005
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.0129 0.0123
Loa Loa (eye worm) TK/INSR protein kinase 0.0059 0.0114 0.021
Mycobacterium ulcerans DNA gyrase subunit A 0.0036 0.0036 0.0083
Echinococcus granulosus neuropeptide receptor A26 0.1774 0.5868 0.5903
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0043 0.0036
Echinococcus multilocularis serotonin receptor 0.0849 0.2763 0.278
Schistosoma mansoni hypothetical protein 0.0147 0.041 0.0416
Brugia malayi N-terminal motif family protein 0.0212 0.0627 0.1046
Echinococcus multilocularis NMDA receptor 0.0083 0.0193 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Schistosoma mansoni apoptosis regulator bax 0.0088 0.021 0.021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3005 1 1
Echinococcus multilocularis GPCR, family 2 0.0068 0.0144 0.0145
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0162 0.0458 0.084
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis short transient receptor potential channel 6 0.006 0.0117 0.0118
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0037 0.004 0.004
Echinococcus granulosus chromobox protein 1 0.0107 0.0273 0.0275
Onchocerca volvulus 0.031 0.0955 0.2331
Schistosoma mansoni intermediate filament proteins 0.0088 0.0209 0.021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2265 0.7516 0.7513
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0263 0.0797 0.0788
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Trypanosoma cruzi calmodulin, putative 0.0029 0.0014 0.0007
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0083 0.0193 0.0194
Loa Loa (eye worm) hypothetical protein 0.0123 0.0327 0.0601
Onchocerca volvulus 0.0263 0.0797 0.1943
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0086 0.0204 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0084 0.0198 0.0385
Schistosoma mansoni hypothetical protein 0.0035 0.0032 0.0028
Plasmodium falciparum DNA gyrase subunit B 0.0097 0.0242 0.0463
Plasmodium vivax ferrodoxin reductase, putative 0.0263 0.0797 0.1544
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.031 0.0955 0.0975
Schistosoma mansoni hypothetical protein 0.0083 0.0193 0.0192
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.019 0.0553 0.0548
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0086 0.0204 0.0205
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus sodium channel protein 0.0629 0.2026 0.2038
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0143 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0423 0.1019
Schistosoma mansoni hypothetical protein 0.0205 0.0602 0.0613
Brugia malayi Bromodomain containing protein 0.0044 0.0064 0.0098
Echinococcus multilocularis orexin receptor type 2 0.031 0.0955 0.096
Schistosoma mansoni jumonji domain containing protein 0.009 0.0219 0.022
Schistosoma mansoni neuropeptide receptor 0.031 0.0955 0.0975
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0199 0.0468
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0263 0.0797 0.2441
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0125 0.0202
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0113 0.0294 0.0705
Brugia malayi nuclear receptor NHR-88 0.0062 0.0125 0.0202
Loa Loa (eye worm) voltage-gated potassium channel 0.006 0.0116 0.0212
Brugia malayi Tachykinin-like peptides receptor 99D 0.031 0.0955 0.1598
Echinococcus granulosus potassium large conductance calcium activated 0.006 0.0116 0.0116
Schistosoma mansoni biogenic amine receptor 0.031 0.0955 0.0975
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0014 0.0015
Entamoeba histolytica hypothetical protein 0.0037 0.004 0.0156
Loa Loa (eye worm) hypothetical protein 0.0976 0.319 0.5856
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0014 0.0027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0125 0.0202
Echinococcus granulosus short transient receptor potential channel 6 0.006 0.0116 0.0116
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0263 0.0797 0.3728
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0989 0.3235 0.6326
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0032 0.0059
Toxoplasma gondii endonuclease IV APN 0.0168 0.0478 0.0926
Echinococcus multilocularis glutamate receptor NMDA 0.0094 0.0231 0.0233
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0308 0.0302
Schistosoma mansoni transient receptor potential channel 0.006 0.0116 0.0113
Schistosoma mansoni inositol monophosphatase 0.0117 0.0308 0.0311
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1088 0.3567 0.6547
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.031 0.0313
Giardia lamblia DNA repair protein RAD52 0.0345 0.1075 0.3298
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0116
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0171 0.0491 0.0493
Trypanosoma cruzi NADH dehydrogenase, putative 0.0263 0.0797 0.079
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0086 0.0204 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Echinococcus granulosus insulin receptor 0.0059 0.0114 0.0115
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0199 0.0365
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.031 0.0955 0.096
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0043 0.0073
Loa Loa (eye worm) hypothetical protein 0.0088 0.0209 0.0384
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0989 0.3235 1
Schistosoma mansoni hypothetical protein 0.0073 0.0161 0.016
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0144 0.04 0.0393
Schistosoma mansoni retinoic acid receptor RXR 0.0062 0.0125 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0125 0.023
Echinococcus granulosus neuropeptide s receptor 0.1774 0.5868 0.5903
Echinococcus multilocularis calmodulin 0.0029 0.0014 0.0014
Brugia malayi ion channel NompC 0.006 0.0116 0.0186
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0068 0.0143 0.0144
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0157 0.0443 0.0858
Schistosoma mansoni jun-related protein 0.0149 0.0417 0.0423
Treponema pallidum hypothetical protein 0.012 0.0318 0.0957
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0386 0.1211 0.2368
Leishmania major extracellular receptor, putative 0.0027 0.0007 0.0001
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0014 0.0015
Echinococcus multilocularis adenylate cyclase 9 0.0093 0.0227 0.0229
Brugia malayi Pre-SET motif family protein 0.0157 0.0443 0.0737
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0472 0.1141
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0339
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0171 0.0489 0.0956
Loa Loa (eye worm) hypothetical protein 0.007 0.0151 0.0276
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Leishmania major hypothetical protein, conserved 0.0107 0.0273 0.0268
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0035 0.0031 0.0061
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Echinococcus multilocularis nmda type glutamate receptor 0.0121 0.0322 0.0324
Echinococcus granulosus tyrosine kinase 0.0031 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0175 0.0504 0.0925
Schistosoma mansoni amine GPCR 0.031 0.0955 0.0975
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0036 0.0036 0.0032
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Schistosoma mansoni amine GPCR 0.031 0.0955 0.0975
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0162 0.0458 0.046
Plasmodium vivax DNA gyrase subunit B, putative 0.0097 0.0242 0.0456
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0263 0.0797 0.1332
Toxoplasma gondii cytochrome p450 superfamily protein 0.0084 0.0198 0.0377
Trichomonas vaginalis glutamate synthase, putative 0.0263 0.0797 0.1939
Loa Loa (eye worm) neuropeptide F receptor 0.031 0.0955 0.1752
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0039 0.003
Leishmania major hypothetical protein, conserved 0.0029 0.0012 0.0007
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0047 0.0109
Giardia lamblia Rho GAP, putative 0.0066 0.0136 0.0386
Giardia lamblia Kinase, CMGC MAPK 0.0166 0.0472 0.1428
Leishmania major hypothetical protein, conserved 0.0075 0.0168 0.0162
Trichomonas vaginalis glucosylceramidase, putative 0.0568 0.1823 0.4466
Plasmodium vivax hypothetical protein, conserved 0.0118 0.031 0.059
Plasmodium vivax ABC transporter G family member 2, putative 0.0044 0.0063 0.0106
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0302 0.093 0.2855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0067
Schistosoma mansoni hypothetical protein 0.0088 0.021 0.021
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Schistosoma mansoni lamin 0.0088 0.0209 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.026 0.0618
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0029 0.0012 0.0011
Brugia malayi G-protein coupled receptor 0.031 0.0955 0.1598
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0391 0.1226 0.1234
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0084 0.0198 0.0385
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Trichomonas vaginalis chromobox protein, putative 0.0107 0.0273 0.0651
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.004 0.0156
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0989 0.3235 0.633
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0075 0.0168 0.0311
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0185 0.0536 0.0545
Brugia malayi Dopamine receptor protein 1 0.0803 0.2612 0.4386
Brugia malayi intermediate filament protein 0.0088 0.0209 0.0343
Onchocerca volvulus 0.0035 0.0034 0.0067
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0158 0.0445 0.0436
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus RUN 0.0088 0.0209 0.0211
Mycobacterium tuberculosis Possible oxygenase 0.0029 0.0012 0.0022
Echinococcus multilocularis neuropeptides capa receptor 0.031 0.0955 0.096
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0044 0.0063 0.0114
Brugia malayi GnHR receptor homolog 0.031 0.0955 0.1598
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0199 0.0199
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0125 0.0126
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Schistosoma mansoni chromobox protein 0.0107 0.0273 0.0275
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0171 0.0491 0.0498
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0097 0.0242 0.0721
Treponema pallidum fructose-bisphosphate aldolase 0.0658 0.2125 0.656
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0064 0.0129 0.0127
Plasmodium falciparum amino acid transporter, putative 0.0118 0.031 0.0597
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0038 0.0043 0.0034
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.031 0.0955 0.1752
Toxoplasma gondii Erv1 / Alr family protein 0.0075 0.0168 0.0318
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Loa Loa (eye worm) hypothetical protein 0.0099 0.0247 0.0454
Brugia malayi olfactory channel protein osm-9 0.006 0.0117 0.0188
Loa Loa (eye worm) hypothetical protein 0.0047 0.0072 0.0133
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0084 0.0198 0.0385
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Echinococcus multilocularis voltage dependent calcium channel 0.0171 0.0491 0.0493
Plasmodium vivax ataxin-2 like protein, putative 0.0107 0.0273 0.0518
Entamoeba histolytica hypothetical protein 0.0073 0.0161 0.0727
Onchocerca volvulus Heterochromatin protein 1 homolog 0.007 0.0151 0.0354
Brugia malayi Serotonin receptor 0.1797 0.5947 1
Schistosoma mansoni single-minded 0.0048 0.0076 0.0072
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0144 0.04 0.1856
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0039 0.0074
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.006 0.0116 0.0107
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0121 0.0121
Echinococcus granulosus potassium voltage gated channel protein 0.006 0.0116 0.0116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0084 0.0081
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.031 0.0955 0.096
Echinococcus granulosus biogenic amine 5HT receptor 0.1581 0.5223 0.5254
Trichomonas vaginalis chromobox protein, putative 0.0107 0.0273 0.0651
Brugia malayi Protein cec-1. 0.0037 0.004 0.0058
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0064 0.0129 0.013
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0593 0.1906 0.5881
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.031 0.0313
Echinococcus multilocularis G-protein coupled receptor, putative 0.031 0.0955 0.096
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0125 0.0202
Schistosoma mansoni zinc finger protein 0.0029 0.0014 0.0009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Mycobacterium ulcerans hypothetical protein 0.0146 0.0404 0.1224
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0989 0.3235 0.6324
Brugia malayi cytoplasmic intermediate filament protein 0.0047 0.0073 0.0114
Leishmania major mitochondrial DNA topoisomerase II 0.0187 0.0543 0.0538
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis neuropeptides capa receptor 0.031 0.0955 0.096
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0263 0.0797 0.2441
Schistosoma mansoni inositol 145-trisphosphate receptor 0.006 0.0116 0.0113
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Brugia malayi hypothetical protein 0.0222 0.0661 0.1104
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0164 0.0466 0.1126
Brugia malayi Calcitonin receptor-like protein seb-1 0.0216 0.0639 0.1067
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0097 0.0242 0.0463
Schistosoma mansoni voltage-gated ion channel 0.006 0.0116 0.0113
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Loa Loa (eye worm) hypothetical protein 0.0147 0.041 0.0753
Schistosoma mansoni cytochrome P450 0.0084 0.0198 0.0197
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0199 0.0199
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0422 0.1332 0.4102
Echinococcus granulosus lipoxygenase domain containing protein 0.0088 0.0209 0.0211
Schistosoma mansoni myosin xvIII 0.031 0.0955 0.0975
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0263 0.0797 0.0801
Onchocerca volvulus 0.0088 0.0209 0.0498
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0168 0.0478 0.0934
Brugia malayi hypothetical protein 0.1003 0.3282 0.5515
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Brugia malayi RhoGAP domain containing protein 0.0066 0.0136 0.0221
Schistosoma mansoni glutamate receptor NMDA 0.0391 0.1226 0.1254
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0797 0.079
Echinococcus multilocularis inositol monophosphatase 1 0.0117 0.0308 0.031
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0043 0.0084
Treponema pallidum hypothetical protein 0.0031 0.002 0.0032
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0171 0.0489 0.1489
Echinococcus granulosus calmodulin 0.0029 0.0013 0.0014
Leishmania major NADH dehydrogenase, putative 0.0263 0.0797 0.0792
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0026 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0099 0.0247 0.0248
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.006 0.0116 0.0116
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0143 0.0137
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0084 0.0198 0.0584
Echinococcus granulosus Polycystic kidney disease protein 0.0088 0.0209 0.0211
Brugia malayi voltage-dependent calcium channel 0.006 0.0116 0.0186
Leishmania major calmodulin, putative 0.0029 0.0014 0.0008
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0263 0.0797 0.1544
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.031 0.0955 0.0975
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0125 0.0202
Schistosoma mansoni hypothetical protein 0.1403 0.4623 0.4743
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0308 0.0302
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.031 0.0955 0.0975
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0084 0.0198 0.0191
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.0129 0.0237
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0084 0.0198 0.0385
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0084 0.0198 0.0385
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.006 0.0116 0.0109
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0263 0.0797 0.2163
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0308 0.0738
Loa Loa (eye worm) hypothetical protein 0.016 0.0453 0.0831
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.031 0.0313
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022 0.0655 0.0659
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.004 0.0156
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0302 0.0305
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2265 0.7516 0.7514
Mycobacterium leprae Conserved hypothetical protein 0.0084 0.0198 0.0518
Plasmodium vivax ferredoxin, putative 0.0029 0.0012 0.0006
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.002 0.0029
Echinococcus multilocularis Chromobox protein 3 0.0037 0.004 0.004
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0039 0.0039
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0068 0.0143 0.0144
Brugia malayi hypothetical protein 0.0029 0.0014 0.0015
Plasmodium vivax heterochromatin protein 1, putative 0.0037 0.004 0.006
Plasmodium vivax SET domain protein, putative 0.0157 0.0443 0.0851
Trichomonas vaginalis DNA topoisomerase II, putative 0.0167 0.0475 0.1148
Onchocerca volvulus 0.0194 0.0568 0.1379
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0084 0.0198 0.0385
Brugia malayi MAP kinase sur-1 0.0166 0.0472 0.0786
Loa Loa (eye worm) hypothetical protein 0.0849 0.2763 0.5073
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.006 0.0116 0.0186
Echinococcus granulosus cGMP dependent protein kinase 1 0.0027 0.0005 0.0005
Schistosoma mansoni adrenodoxin 0.0029 0.0012 0.0007
Onchocerca volvulus 0.006 0.0116 0.0268
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0099 0.0247 0.0249
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Echinococcus granulosus geminin 0.1403 0.4623 0.465
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1191 0.3912 0.6574
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0339
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0175 0.0504 0.0512
Echinococcus multilocularis conserved hypothetical protein 0.2231 0.7404 0.7448
Echinococcus granulosus sodium and chloride dependent glycine 0.0118 0.031 0.0312
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.031 0.0955 0.096
Schistosoma mansoni cpg binding protein 0.0068 0.0145 0.0144
Leishmania major trypanothione reductase 0.1548 0.511 0.5107
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0184 0.0532 0.0536
Loa Loa (eye worm) blistered cuticle protein 3 0.0231 0.0692 0.1269
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0273 0.0525
Onchocerca volvulus 0.0118 0.031 0.0747
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0386 0.1211 0.2368
Schistosoma mansoni hypothetical protein 0.0037 0.004 0.0035
Schistosoma mansoni hypothetical protein 0.0068 0.0144 0.0143
Entamoeba histolytica hypothetical protein 0.0073 0.0161 0.0727
Brugia malayi putative neuropeptide receptor NPR1 0.031 0.0955 0.1598
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0144 0.04 0.0391
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.031 0.0955 0.0975
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0472 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0259 0.0617
Loa Loa (eye worm) hypothetical protein 0.0039 0.0045 0.0084
Loa Loa (eye worm) norepinephrine transporter 0.0693 0.2241 0.4114
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Brugia malayi nuclear receptor RXR 0.0033 0.0026 0.0035
Echinococcus granulosus chromobox protein 1 0.0107 0.0273 0.0275
Loa Loa (eye worm) hypothetical protein 0.0693 0.2241 0.4114
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0117 0.0118
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis g-protein coupled receptor 0.031 0.0955 0.096
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0086 0.0204 0.0205
Brugia malayi G protein-coupled receptor F59B2.13 0.031 0.0955 0.1598
Schistosoma mansoni glutamate receptor AMPA 0.0193 0.0564 0.0573
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0039 0.0039
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0083 0.0193 0.0194
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0076 0.0072
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0119 0.0119
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0263 0.0797 0.1557
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0125 0.0202
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0037 0.004 0.0035
Trypanosoma brucei calmodulin 0.0029 0.0014 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0989 0.3235 1
Loa Loa (eye worm) serotonin transporter b 0.0693 0.2241 0.4114
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0302 0.0293
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Schistosoma mansoni tyrosine kinase 0.0059 0.0114 0.0112
Onchocerca volvulus 0.0035 0.0031 0.0061
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Schistosoma mansoni biogenic amine (5HT) receptor 0.1581 0.5223 0.5359
Brugia malayi RhoGAP domain containing protein 0.0076 0.0171 0.028
Echinococcus multilocularis calcium activated potassium channel 0.0062 0.0122 0.0123
Trypanosoma brucei PAB1-binding protein , putative 0.0107 0.0273 0.0264
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Loa Loa (eye worm) hypothetical protein 0.1648 0.5448 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0423 0.1019
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Trypanosoma cruzi calmodulin, putative 0.0029 0.0014 0.0007
Schistosoma mansoni rab6-interacting 0.0088 0.0209 0.0209
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0386 0.1211 0.3302
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.006 0.0116 0.0216
Echinococcus granulosus neuropeptide FF receptor 2 0.031 0.0955 0.096
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0129 0.0297
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0084 0.0133
Echinococcus multilocularis neuropeptide receptor 0.031 0.0955 0.096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0175 0.0504 0.0512
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0014 0.0015
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0075 0.0168 0.0161
Mycobacterium ulcerans epimerase 0.0044 0.0063 0.0168
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0161 0.0162
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0263 0.0797 0.1939
Echinococcus granulosus potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Echinococcus granulosus histone lysine methyltransferase setb 0.0175 0.0504 0.0507
Toxoplasma gondii transporter, cation channel family protein 0.0081 0.0186 0.0355
Echinococcus granulosus mitogen activated protein kinase 3 0.0166 0.0472 0.0475
Brugia malayi neuropeptide F receptor 0.031 0.0955 0.1598
Echinococcus multilocularis ATP binding cassette sub family G 0.0044 0.0063 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.0088 0.0209 0.0211
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0125 0.0126
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0039 0.0039
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022 0.0655 0.0659
Schistosoma mansoni neuropeptide F-like receptor 0.031 0.0955 0.0975
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.031 0.0955 0.096
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0302 0.0909
Echinococcus granulosus neuropeptides capa receptor 0.031 0.0955 0.096
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0118 0.031 0.0934
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Trypanosoma cruzi calmodulin 0.0029 0.0014 0.0007
Schistosoma mansoni zinc finger protein 0.0028 0.0009 0.0004
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0037 0.004 0.0068
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0125 0.0126
Echinococcus multilocularis potassium voltage gated channel protein 0.006 0.0116 0.0116
Trichomonas vaginalis Ferredoxin 3 0.0029 0.0012 0.0008
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0084 0.0199 0.02
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Brugia malayi Blistered cuticle protein 3 0.0231 0.0692 0.1155
Echinococcus granulosus somatostatin receptor 0.031 0.0955 0.096
Echinococcus granulosus neuropeptide receptor 0.031 0.0955 0.096
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0084 0.0198 0.0584
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0032 0.0045
Echinococcus multilocularis Rac GTPase activating protein 1 0.0076 0.0171 0.0173
Echinococcus multilocularis mitogen activated protein kinase 0.0166 0.0472 0.0475
Echinococcus multilocularis epidermal growth factor receptor 0.0098 0.0244 0.0246
Echinococcus multilocularis mitogen activated protein kinase 3 0.0166 0.0472 0.0475
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0039 0.0056
Entamoeba histolytica protein kinase, putative 0.0069 0.0147 0.0664
Echinococcus multilocularis lipoxygenase domain containing protein 0.0088 0.0209 0.0211
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0009 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0014 0.0015
Loa Loa (eye worm) melatonin receptor type 1A 0.031 0.0955 0.1752
Loa Loa (eye worm) phosphatidylinositol 3 0.019 0.0553 0.1015
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Echinococcus granulosus sodium and chloride dependent glycine 0.0118 0.031 0.0312
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0088 0.0209 0.0384
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0185 0.0536 0.0545
Trypanosoma cruzi NADH dehydrogenase, putative 0.0263 0.0797 0.079
Loa Loa (eye worm) programmed cell death 8 0.0263 0.0797 0.1462
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0116
Schistosoma mansoni chromobox protein 0.0107 0.0273 0.0275
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0273 0.0267
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0171 0.0491 0.0493
Schistosoma mansoni ABC transporter 0.0037 0.0041 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0216 0.0639 0.1067
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0084 0.0198 0.0385
Loa Loa (eye worm) voltage-dependent calcium channel 0.0081 0.0186 0.0342
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0014 0.0009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0989 0.3235 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Echinococcus granulosus transcription factor Dp 1 0.0084 0.0196 0.0197
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Chlamydia trachomatis ferredoxin 0.0029 0.0012 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0107 0.0273 0.0525
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0066 0.014
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0009 0.0007
Schistosoma mansoni ryanodine receptor related 0.006 0.0116 0.0113
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.031 0.0313
Schistosoma mansoni hypothetical protein 0.0068 0.0144 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0423 0.1019
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0027 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0084 0.0198 0.0584
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.057
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0263 0.0797 0.2434
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0144 0.0145
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0097 0.0242 0.0721
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0086 0.0204 0.0205
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Schistosoma mansoni biogenic amine (5HT) receptor 0.0849 0.2763 0.2833
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0038 0.0043 0.0037
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0076 0.0076
Echinococcus multilocularis glutamate synthase 0.0263 0.0797 0.0801
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0117 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0151 0.0349
Echinococcus granulosus tachykinin peptides receptor 99D 0.031 0.0955 0.096
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0027 0.0007 0.0007
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0263 0.0797 0.1332
Echinococcus multilocularis g protein coupled receptor 0.031 0.0955 0.096
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0597
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0037 0.0039 0.0074
Echinococcus granulosus nmda type glutamate receptor 0.0121 0.0322 0.0324
Echinococcus granulosus serine protein kinase ATM 0.0036 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0088 0.0209 0.0209
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0161 0.0162
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0088 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0036 0.0036 0.0036
Brugia malayi conserved hypotetical protein 0.0029 0.0014 0.0015
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0121 0.0234
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0014 0.0015
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0263 0.0797 0.0801
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0088 0.021 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0553 0.134
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162 0.046 0.1111
Echinococcus granulosus tyrosine protein kinase Src42A 0.0086 0.0204 0.0205
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0036 0.0036 0.006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0128 0.0344 0.0346
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0014 0.0009
Mycobacterium ulcerans oxygenase 0.0029 0.0012 0.0009
Echinococcus multilocularis g protein coupled receptor 0.031 0.0955 0.096
Echinococcus multilocularis two pore calcium channel protein 1 0.006 0.0116 0.0116
Echinococcus multilocularis voltage gated potassium channel 0.006 0.0116 0.0116
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.006 0.0116 0.0186
Echinococcus multilocularis serine protein kinase ATM 0.0036 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.004 0.005 0.0092
Loa Loa (eye worm) hypothetical protein 0.0976 0.319 0.5856
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0989 0.3235 0.6326
Brugia malayi Adenylyl cyclase protein 0.0093 0.0227 0.0374
Mycobacterium leprae putative cytochrome p450 0.0084 0.0198 0.0518
Echinococcus granulosus nmda type glutamate receptor 0.0222 0.066 0.0664
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0822 0.2674 0.4491
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0084 0.0198 0.0584
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0989 0.3235 0.6324
Schistosoma mansoni sodium/chloride dependent transporter 0.0118 0.031 0.0313
Trichomonas vaginalis chromobox protein, putative 0.0037 0.004 0.0077
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0895 0.2921 0.7168
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0263 0.0797 0.2441
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0125 0.0202
Onchocerca volvulus Alhambra homolog 0.0035 0.0032 0.0063
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0032 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.006 0.0116 0.0116
Echinococcus multilocularis calmodulin 0.0029 0.0013 0.0014
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0412 0.0418
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0045 0.0067 0.0179
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.006 0.0116 0.0113
Leishmania major hypothetical protein, conserved 0.0263 0.0797 0.0792
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0989 0.3235 1
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Loa Loa (eye worm) ABC transporter 0.0037 0.0041 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Onchocerca volvulus 0.031 0.0955 0.2331
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0125 0.0126
Schistosoma mansoni neuropeptide F-like receptor 0.031 0.0955 0.0975
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0084 0.0198 0.0584
Echinococcus granulosus 7TM GPCR rhodopsin 0.031 0.0955 0.096
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0044 0.0063 0.0139
Brugia malayi nuclear hormone receptor 0.0062 0.0125 0.0202
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0044 0.0065
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0322 0.0995 0.2708
Schistosoma mansoni metabotropic glutamate receptor 0.0027 0.0007 0.0001
Brugia malayi Dopamine receptor protein 2 0.031 0.0955 0.1598
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0043 0.0059 0.0059
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0012 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0105 0.0267 0.0709
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0032 0.0032
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0386 0.1211 0.2368
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Brugia malayi PHD-finger family protein 0.0035 0.0032 0.0045
Schistosoma mansoni neuropeptide receptor 0.031 0.0955 0.0975
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0166 0.0472 0.0466
Onchocerca volvulus 0.0093 0.0227 0.0543
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0026 0.0022
Brugia malayi nuclear receptor NHR-67 0.0029 0.0014 0.0015
Onchocerca volvulus 0.0037 0.0038 0.0077
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0263 0.0797 0.079
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2987 0.9941 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0297 0.0708
Onchocerca volvulus 0.031 0.0955 0.2331
Brugia malayi metabotropic glutamate receptor type 2 0.0027 0.0007 0.0002
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0117 0.0118
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0084 0.0199 0.0199
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0118 0.031 0.0312
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.031 0.0313
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis shaker cognate 0.006 0.0116 0.0116
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0068 0.0122
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.006 0.0116 0.0186
Echinococcus granulosus jumonji domain containing protein 0.0048 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Brugia malayi hypothetical protein 0.0033 0.0026 0.0035
Loa Loa (eye worm) isocitrate dehydrogenase 0.0068 0.0143 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Onchocerca volvulus 0.031 0.0955 0.2331
Schistosoma mansoni glutamate synthase 0.0263 0.0797 0.0813
Loa Loa (eye worm) TOPoisomerase family member 0.0167 0.0475 0.0872
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0144 0.0234
Schistosoma mansoni glutamate receptor kainate 0.0193 0.0564 0.0573
Schistosoma mansoni calmodulin 0.0029 0.0014 0.0008
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0014 0.0015
Echinococcus granulosus inositol monophosphatase 1 0.0117 0.0308 0.031
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0044 0.0063 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0339
Trypanosoma cruzi calmodulin 0.0029 0.0014 0.0007
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0199 0.0468
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.002 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2265 0.7516 0.7514
Echinococcus granulosus hyperpolarization activated cyclic 0.0084 0.0199 0.02
Giardia lamblia Calmodulin 0.0029 0.0014 0.0004
Brugia malayi chromobox protein homolog 3 0.007 0.0151 0.0244
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Schistosoma mansoni sodium-dependent amino acid transporter 0.0118 0.031 0.0313
Schistosoma mansoni glutamate receptor kainate 0.0193 0.0564 0.0573
Trypanosoma cruzi DNA topoisomerase II, putative 0.0158 0.0445 0.0438
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0144 0.0145
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0263 0.0797 0.079
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0039 0.0032
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0034 0.0034
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0162 0.0458 0.084
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Leishmania major ferric reductase, putative 0.0109 0.028 0.0275
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0125 0.0202
Echinococcus multilocularis lamin 0.0088 0.0209 0.0211
Trypanosoma brucei hypothetical protein, conserved 0.0263 0.0797 0.0788
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0125 0.0202
Plasmodium falciparum ABC transporter G family member 2 0.0044 0.0063 0.0114
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0302 0.093 0.2855
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0084 0.0199 0.02
Toxoplasma gondii hypothetical protein 0.0118 0.031 0.0597
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0084 0.0198 0.0584
Echinococcus granulosus sex peptide receptor 0.031 0.0955 0.096
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0039 0.0074
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0068 0.0143 0.0134
Mycobacterium ulcerans oxidoreductase 0.0029 0.0012 0.0009
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0263 0.0797 0.0801
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0125 0.0126
Schistosoma mansoni glutamate receptor NMDA 0.0314 0.097 0.0991
Echinococcus multilocularis chromobox protein 2 0.0037 0.004 0.004
Schistosoma mansoni opsin-like receptor 0.031 0.0955 0.0975
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0302 0.0296
Brugia malayi Inositol-1 0.0117 0.0308 0.051
Schistosoma mansoni nuclear receptor 0.0029 0.0014 0.0009
Echinococcus multilocularis TRP (transient receptor potential) channel 0.006 0.0116 0.0116
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0068 0.0122
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0068 0.0143 0.0136
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0109 0.028 0.0273
Brugia malayi Glutamate receptor 2 precursor 0.0193 0.0564 0.094
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.022 0.0655 0.0659
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0126 0.034 0.0333
Echinococcus multilocularis hyperpolarization activated cyclic 0.0084 0.0199 0.02
Schistosoma mansoni hypothetical protein 0.0149 0.0417 0.0423
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0263 0.0797 0.3728
Brugia malayi hypothetical protein 0.016 0.0453 0.0753
Loa Loa (eye worm) hypothetical protein 0.0037 0.0038 0.007
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0043 0.0079
Mycobacterium ulcerans NADH dehydrogenase 0.0263 0.0797 0.2441
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0302 0.0304
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0171 0.0491 0.0493
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0084 0.0198 0.0584
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.031 0.0955 0.096
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0322 0.0995 0.1945
Chlamydia trachomatis DNA gyrase subunit B 0.0077 0.0173 0.0509
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0263 0.0797 0.155
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Entamoeba histolytica hypothetical protein 0.0028 0.0009 0.0011
Echinococcus multilocularis two pore calcium channel protein 2 0.006 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0098 0.0244 0.0245
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0121 0.0219
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0039 0.0083
Loa Loa (eye worm) hypothetical protein 0.0222 0.066 0.1212
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.002 0.0024
Schistosoma mansoni disulfide oxidoreductase 0.0263 0.0797 0.0813
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0245 0.1127
Echinococcus granulosus neuropeptide Y receptor 0.031 0.0955 0.096
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0116 0.0116
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0597
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0125 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Giardia lamblia PHD finger protein 15 0.0035 0.0032 0.0062
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0029 0.0012 0.0009
Echinococcus multilocularis g protein coupled receptor 0.031 0.0955 0.096
Brugia malayi hypoxia-induced factor 1 0.0148 0.0411 0.0683
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Treponema pallidum NADH oxidase 0.0989 0.3235 1
Schistosoma mansoni sulfide quinone reductase 0.0263 0.0797 0.0813
Schistosoma mansoni voltage-gated potassium channel 0.0224 0.0668 0.0681
Schistosoma mansoni nuclear receptor 0.0029 0.0014 0.0009
Brugia malayi glutathione reductase 0.1548 0.511 0.8591
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0038 0.0043 0.0063
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0989 0.3235 0.323
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0161 0.0162
Giardia lamblia ABC transporter 0.0043 0.0061 0.0152
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.002 0.0021
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0037 0.004 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.019 0.0553 0.134
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0045 0.0067 0.0179
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0263 0.0797 0.2163
Echinococcus multilocularis jun protein 0.0184 0.0532 0.0536
Echinococcus granulosus transient receptor potential gamma protein 0.006 0.0116 0.0116
Loa Loa (eye worm) TYRA-2 protein 0.031 0.0955 0.1752
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Mycobacterium ulcerans endonuclease IV 0.0168 0.0478 0.1453
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Echinococcus granulosus potassium voltage gated channel subfamily H 0.021 0.062 0.0624
Echinococcus granulosus glutamate receptor NMDA 0.0094 0.0231 0.0233
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0263 0.0797 0.3728
Echinococcus multilocularis calmodulin 0.0029 0.0014 0.0014
Mycobacterium tuberculosis Probable dehydrogenase 0.0386 0.1211 0.2368
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0125 0.0126
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0125 0.0291
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0263 0.0797 0.079
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0185 0.0537 0.0986
Schistosoma mansoni hypothetical protein 0.0068 0.0144 0.0143
Schistosoma mansoni hypothetical protein 0.0088 0.021 0.021
Echinococcus multilocularis tyrosine protein kinase HCK 0.0069 0.0147 0.0148
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.0129 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0066 0.014
Echinococcus granulosus Chromobox protein 3 0.0037 0.004 0.004
Schistosoma mansoni ap endonuclease 0.0061 0.0121 0.0118
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.0129 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Trichomonas vaginalis mercuric reductase, putative 0.0989 0.3235 0.7942
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0121 0.0275
Loa Loa (eye worm) cytochrome P450 family protein 0.0121 0.0322 0.0591
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.019 0.0553 0.0922
Loa Loa (eye worm) intermediate filament protein 0.0088 0.0209 0.0384
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.031 0.0955 0.0975
Schistosoma mansoni amine GPCR 0.031 0.0955 0.0975
Brugia malayi PHD-finger family protein 0.0034 0.0028 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.021 0.062 0.1138
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0084 0.0198 0.0385
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.039 0.0392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0129 0.0297
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.031 0.0955 0.1752
Echinococcus granulosus glutamate receptor 2 0.0138 0.0378 0.038
Trypanosoma cruzi PAB1-binding protein , putative 0.0107 0.0273 0.0267
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0125 0.0126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.006 0.0116 0.0216
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0125 0.0126
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0084 0.0198 0.0192
Schistosoma mansoni cpg binding protein 0.0068 0.0145 0.0144
Echinococcus granulosus dnaJ subfamily B 0.0894 0.2917 0.2934
Onchocerca volvulus 0.0144 0.04 0.0967
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0263 0.0797 0.155
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.002 0.0034
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0084 0.0198 0.0385
Brugia malayi Cytochrome P450 family protein 0.0121 0.0322 0.0533
Brugia malayi G protein-coupled receptor 0.031 0.0955 0.1598
Loa Loa (eye worm) hypothetical protein 0.1003 0.3282 0.6025
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0083 0.0193 0.0194
Echinococcus granulosus potassium voltage gated channel protein 0.006 0.0116 0.0116
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0263 0.0797 0.0801
Loa Loa (eye worm) hypothetical protein 0.0216 0.0639 0.1173
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0171 0.0491 0.0817
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0302 0.0555
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0039 0.0071
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0084 0.0198 0.0584
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.006 0.0116 0.0116
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0119 0.0113
Leishmania major DNA topoisomerase ii 0.0158 0.0445 0.044
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0144 0.04 0.0664
Schistosoma mansoni tyrosine kinase 0.0059 0.0114 0.0112
Loa Loa (eye worm) hypothetical protein 0.0441 0.1396 0.2563
Schistosoma mansoni hypothetical protein 0.031 0.0955 0.0975
Trichomonas vaginalis Ferredoxin 2 0.0029 0.0012 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0048
Mycobacterium tuberculosis Probable reductase 0.0386 0.1211 0.2368
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0014 0.0027
Brugia malayi M-phase phosphoprotein, mpp8 0.0222 0.066 0.1102
Onchocerca volvulus 0.0088 0.0209 0.0498
Brugia malayi 6-phosphofructokinase 0.0115 0.0302 0.05
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0009 0.0007
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0075 0.0168 0.0169
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0048
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0086 0.0204 0.0205
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0029 0.0012 0.0013
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0726 0.2354 0.3952
Echinococcus multilocularis expressed conserved protein 0.0027 0.0005 0.0005
Schistosoma mansoni protein kinase 0.0035 0.0031 0.0027
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.031 0.0955 0.096
Entamoeba histolytica hypothetical protein 0.0037 0.004 0.0156
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0039 0.0034
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0093 0.0227 0.0543
Brugia malayi nuclear receptor RXR 0.0029 0.0014 0.0015
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0263 0.0797 0.155
Onchocerca volvulus 0.0118 0.031 0.0747
Echinococcus multilocularis neuropeptide Y receptor 0.031 0.0955 0.096
Echinococcus granulosus mitogen activated protein kinase 0.0166 0.0472 0.0475
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0012 0.0005
Trypanosoma brucei NADH dehydrogenase 0.0263 0.0797 0.0788
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0039 0.0152
Trypanosoma cruzi hypothetical protein, conserved 0.0263 0.0797 0.079
Echinococcus multilocularis neuropeptide FF receptor 2 0.031 0.0955 0.096
Loa Loa (eye worm) voltage-gated calcium channel 0.006 0.0116 0.0212
Loa Loa (eye worm) AGC/PKG protein kinase 0.0027 0.0005 0.001
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0084 0.0198 0.0584
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0079 0.018 0.0171
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.006 0.0116 0.0113
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Toxoplasma gondii ferodoxin FD 0.0029 0.0012 0.0013
Echinococcus multilocularis somatostatin receptor 0.031 0.0955 0.096
Echinococcus granulosus lipoxygenase domain containing protein 0.0088 0.0209 0.0211
Loa Loa (eye worm) apoptosis regulator protein 0.0088 0.021 0.0386
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0258 0.078 0.1901
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.021 0.062 0.1035
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0989 0.3235 0.3228
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0302 0.1395
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Onchocerca volvulus 0.0063 0.0126 0.0294
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0125 0.023
Brugia malayi Dopamine receptor 0.031 0.0955 0.1598
Loa Loa (eye worm) hypothetical protein 0.0609 0.1958 0.3594
Echinococcus granulosus cpg binding protein 0.0068 0.0145 0.0146
Brugia malayi tailless protein 0.0029 0.0014 0.0015
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.004 0.0035
Loa Loa (eye worm) hypothetical protein 0.0849 0.2763 0.5073
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0117 0.0308 0.0928
Echinococcus granulosus glutamate receptor subunit protein glur 0.0083 0.0193 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0067
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0119 0.023
Loa Loa (eye worm) doublecortin family protein 0.0088 0.0209 0.0384
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0263 0.0797 0.0801
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.009 0.0217 0.0208
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Onchocerca volvulus 0.031 0.0955 0.2331
Echinococcus multilocularis potassium voltage gated channel protein 0.006 0.0116 0.0116
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.002 0.0021
Echinococcus multilocularis nmda type glutamate receptor 0.0222 0.066 0.0664
Trypanosoma brucei ABC transporter, putative 0.0044 0.0063 0.0054
Brugia malayi Furin-like cysteine rich region family protein 0.018 0.052 0.0867
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0029 0.0012 0.0009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1112 0.3649 0.714
Loa Loa (eye worm) cytochrome P450 0.0084 0.0198 0.0363
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0057 0.0058
Echinococcus granulosus g protein coupled receptor 0.031 0.0955 0.096
Echinococcus granulosus biogenic amine 5HT receptor 0.0849 0.2763 0.278
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0125 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.2987 0.9941 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0084 0.0198 0.0584
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0031 0.0058
Brugia malayi Thioredoxin reductase 0.1548 0.511 0.8591
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0014 0.0015
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0084 0.0198 0.0584
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Echinococcus multilocularis neuropeptide Y receptor 0.031 0.0955 0.096
Loa Loa (eye worm) hypoxia-induced factor 1 0.0148 0.0411 0.0755
Echinococcus multilocularis 0.0055 0.01 0.0101
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0989 0.3235 0.5435
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0057 0.0058
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0263 0.0797 0.2441
Echinococcus multilocularis jumonji domain containing protein 0.0048 0.0078 0.0078
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Schistosoma mansoni neuropeptide receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.0693 0.2241 0.4114
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0014 0.0009
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0144 0.04 0.0395
Echinococcus multilocularis dnaJ subfamily B 0.0894 0.2917 0.2934
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.0091 0.0222 0.0408
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.004 0.0077
Onchocerca volvulus 0.0222 0.066 0.1607
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0045 0.0089
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0302 0.1395
Loa Loa (eye worm) ryanodine receptor 0.006 0.0116 0.0212
Loa Loa (eye worm) hypothetical protein 0.0113 0.0294 0.054
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0027 0.0007 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0162 0.0378
Plasmodium falciparum DNA gyrase subunit A 0.0036 0.0036 0.006
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.031 0.0955 0.1752
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0263 0.0797 0.155
Schistosoma mansoni histamine h1 receptor 0.031 0.0955 0.0975
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.002 0.0029
Trichomonas vaginalis glutathione reductase, putative 0.0989 0.3235 0.7942
Mycobacterium ulcerans hypothetical protein 0.0044 0.0063 0.0168
Brugia malayi Isocitrate dehydrogenase 0.0068 0.0143 0.0231
Echinococcus granulosus metabotropic glutamate receptor 5 0.0027 0.0007 0.0007
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0037 0.004 0.0035
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Brugia malayi G-protein coupled receptor 0.031 0.0955 0.1598
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0068 0.0115
Mycobacterium ulcerans monoxygenase 0.0263 0.0797 0.2441
Schistosoma mansoni DNA topoisomerase II 0.0167 0.0475 0.0482
Schistosoma mansoni neuropeptide receptor 0.031 0.0955 0.0975
Brugia malayi ABC transporter family protein 0.0037 0.0041 0.006
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0125 0.0291
Loa Loa (eye worm) hypothetical protein 0.0068 0.0144 0.0265
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0014 0.0015
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0185 0.0536 0.0539
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0029 0.0012 0.0011
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0088 0.021 0.0345
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0076 0.0072
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Brugia malayi Melatonin receptor type 1A 0.031 0.0955 0.1598
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.006 0.0116 0.0186
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.006 0.0116 0.0186
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0125 0.0126
Schistosoma mansoni sulfide quinone reductase 0.0263 0.0797 0.0813
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0129 0.0297
Echinococcus multilocularis cpg binding protein 0.0068 0.0145 0.0146
Schistosoma mansoni polycystin 1-related 0.0088 0.0209 0.0209
Schistosoma mansoni transient receptor potential channel 4 0.006 0.0116 0.0113
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0044 0.0063 0.0168
Onchocerca volvulus 0.0029 0.0013 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0423 0.1019
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0036 0.0036 0.0068
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0084 0.0198 0.0385
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0014 0.0015
Schistosoma mansoni inositol monophosphatase 0.0117 0.0308 0.0311
Echinococcus multilocularis tachykinin peptides receptor 99D 0.031 0.0955 0.096
Loa Loa (eye worm) hypothetical protein 0.1191 0.3912 0.718
Trypanosoma brucei cytochrome P450, putative 0.0121 0.0322 0.0313
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0047 0.0191
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.2561 0.8512 0.851
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0031 0.0058
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0125 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0087 0.0192
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0121 0.0537
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.019 0.0553 0.0556
Giardia lamblia Thioredoxin reductase 0.0263 0.0797 0.2434
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Echinococcus multilocularis receptor type guanylyl cyclase 0.0035 0.0031 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.031 0.0955 0.096
Echinococcus granulosus potassium voltage gated channel protein 0.006 0.0116 0.0116
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.0121 0.0346
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0026 0.0035
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0989 0.3235 0.3254
Leishmania major cytochrome p450-like protein 0.0084 0.0198 0.0192
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0032 0.0032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0014 0.0019
Chlamydia trachomatis DNA gyrase subunit A 0.0036 0.0036 0.0083
Schistosoma mansoni cpg binding protein 0.0063 0.0126 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0036 0.0067
Loa Loa (eye worm) hypothetical protein 0.0254 0.0766 0.1407
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0084 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0039 0.0034
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0005 0.0005
Schistosoma mansoni rac gtpase activating protein 0.0076 0.0171 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0423 0.1019
Loa Loa (eye worm) hypothetical protein 0.0068 0.0143 0.0263
Echinococcus multilocularis zinc finger protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0168 0.0478 0.0877
Schistosoma mansoni tyrosine kinase 0.0031 0.0018 0.0013
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0263 0.0797 0.155
Entamoeba histolytica calmodulin, putative 0.0029 0.0014 0.0032
Schistosoma mansoni hypothetical protein 0.0028 0.0009 0.0004
Onchocerca volvulus 0.031 0.0955 0.2331
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0449 0.1421 0.143
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0125 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0084 0.0198 0.0385
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.002 0.0028
Echinococcus granulosus calmodulin 0.0029 0.0014 0.0014
Onchocerca volvulus 0.0205 0.0602 0.1465
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0125 0.0126
Toxoplasma gondii LsmAD domain-containing protein 0.0107 0.0273 0.0525
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0302 0.0909
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0084 0.0198 0.0584
Toxoplasma gondii exonuclease III APE 0.0061 0.0121 0.0226
Brugia malayi Receptor family ligand binding region containing protein 0.0035 0.0031 0.0044
Echinococcus granulosus glutamate NMDA receptor subunit 0.0391 0.1226 0.1234
Echinococcus granulosus thioredoxin glutathione reductase 0.1548 0.511 0.514
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0113 0.0294 0.0705
Brugia malayi sulfakinin receptor protein 0.031 0.0955 0.1598
Schistosoma mansoni opsin-like receptor 0.031 0.0955 0.0975
Echinococcus granulosus glutamate synthase 0.0263 0.0797 0.0801
Brugia malayi gonadotropin-releasing hormone receptor 2 0.031 0.0955 0.1598
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Onchocerca volvulus 0.0693 0.2241 0.5496
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0472 0.1141
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0302 0.0722
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0029 0.0012 0.0022
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0027 0.0007 0.0007
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0028 0.0009 0.0009
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0014 0.0015
Trichomonas vaginalis glutamate synthase, putative 0.0263 0.0797 0.1939
Brugia malayi Valyl-tRNA synthetase 0.0037 0.004 0.0058
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0168 0.0478 0.0919
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0116 0.0116
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0513
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0118 0.031 0.0312
Brugia malayi RE15519p 0.031 0.0955 0.1598
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.031 0.0955 0.096
Echinococcus granulosus L aminoadipate semialdehyde 0.0099 0.0248 0.025
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0185 0.0536 0.0539
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0044 0.0063 0.0058
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Chlamydia trachomatis DNA gyrase subunit B 0.0097 0.0242 0.0721
Loa Loa (eye worm) adenylyl cyclase 3 0.0093 0.0227 0.0417
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0107 0.0273 0.0501
Loa Loa (eye worm) thioredoxin reductase 0.1548 0.511 0.9379
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0157 0.0443 0.0446
Echinococcus multilocularis tyrosine protein kinase Blk 0.0078 0.0176 0.0177
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0166 0.0472 0.0466
Brugia malayi putative neuropeptide receptor 0.031 0.0955 0.1598
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0263 0.0797 0.0792
Brugia malayi Bromodomain containing protein 0.0041 0.0053 0.008
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0121 0.0194
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0045 0.0067 0.0179
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0084 0.0199 0.0365
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0105 0.0267 0.0521
Echinococcus granulosus peregrin 0.0041 0.0053 0.0053
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.0063 0.0168
Onchocerca volvulus 0.1239 0.4072 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0693 0.2241 0.692
Loa Loa (eye worm) hypothetical protein 0.0088 0.021 0.0386
Onchocerca volvulus 0.031 0.0955 0.2331
Onchocerca volvulus Neuropeptide F receptor homolog 0.031 0.0955 0.2331
Entamoeba histolytica hypothetical protein 0.0073 0.0161 0.0727
Schistosoma mansoni tyrosine kinase 0.0095 0.0233 0.0234
Echinococcus multilocularis microtubule associated protein 2 0.2928 0.9741 0.9798
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0125 0.023
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Onchocerca volvulus 0.0088 0.0209 0.0498
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0443 0.045
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0036 0.0036 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0084 0.0198 0.0385
Echinococcus multilocularis ferredoxin adrenodoxin 0.0029 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0062 0.0125 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0129 0.0297
Brugia malayi nuclear hormone receptor 0.0029 0.0014 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0036 0.0052
Brugia malayi ecdysteroid receptor 0.0062 0.0125 0.0202
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0064 0.0129 0.012
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0263 0.0797 0.2441
Loa Loa (eye worm) hypothetical protein 0.0212 0.0627 0.1151
Echinococcus granulosus calmodulin 0.0029 0.0014 0.0014
Echinococcus granulosus short transient receptor potential channel 6 0.006 0.0117 0.0118
Brugia malayi phosphofructokinase 0.0115 0.0302 0.05
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0171 0.0489 0.1489
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0302 0.093 0.1819
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0048
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0038 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0099 0.0248 0.0456
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0026 0.0035
Echinococcus granulosus tumor protein p63 0.1428 0.4709 0.4737
Schistosoma mansoni bromodomain containing protein 0.0074 0.0165 0.0164
Onchocerca volvulus 0.031 0.0955 0.2331
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0166 0.0472 0.0466
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1548 0.511 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0693 0.2241 0.2296
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0121 0.0112
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1112 0.3649 1
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.0088 0.0209 0.0384
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0026 0.0043
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0989 0.3235 0.323
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0263 0.0797 0.0792
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.006 0.0116 0.0186
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0068 0.0145
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0126 0.034 0.0331
Trypanosoma brucei electron transfer protein, putative 0.0029 0.0012 0.0003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0144 0.0145
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0167 0.0475 0.0478
Toxoplasma gondii transporter, cation channel family protein 0.006 0.0116 0.0216
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0118 0.031 0.0513
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0027 0.0005 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0143 0.0144
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0034 0.0077
Leishmania major ferredoxin, 2fe-2s-like protein 0.0029 0.0012 0.0007
Plasmodium falciparum glutathione reductase 0.1548 0.511 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0047 0.0073 0.0134
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0151 0.0423 0.0418
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0075 0.0168 0.0169
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0098 0.0244 0.0246
Echinococcus granulosus hypothetical protein 0.2541 0.8443 0.8493
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0084 0.0198 0.0385
Echinococcus granulosus ferredoxin 0.0029 0.0012 0.0012
Loa Loa (eye worm) voltage-gated potassium channel 0.006 0.0116 0.0212
Loa Loa (eye worm) hypothetical protein 0.0068 0.0143 0.0263
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0064 0.0129 0.012
Echinococcus multilocularis neuropeptide s receptor 0.1774 0.5868 0.5903
Plasmodium vivax hypothetical protein, conserved 0.0037 0.004 0.006
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0037 0.004 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0116 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0297 0.0708
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0038 0.0043 0.017
Toxoplasma gondii ferredoxin, putative 0.0029 0.0012 0.0013
Echinococcus multilocularis calmodulin 0.0029 0.0014 0.0014
Loa Loa (eye worm) CHromoDomain protein family member 0.0043 0.0059 0.0108
Brugia malayi hypothetical protein 0.0088 0.0209 0.0343
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0302 0.0305
Loa Loa (eye worm) glutamate receptor 2 0.0193 0.0564 0.1035
Plasmodium falciparum transporter, putative 0.0118 0.031 0.0597
Echinococcus multilocularis voltage dependent calcium channel 0.0171 0.0491 0.0493
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0068 0.0143 0.0136
Echinococcus multilocularis serotonin receptor 0.0849 0.2763 0.278
Brugia malayi AKH receptor 0.031 0.0955 0.1598
Echinococcus granulosus tyrosine protein kinase Src42A 0.0074 0.0164 0.0165
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0074 0.0164 0.0165
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Echinococcus granulosus peptide allatostatin:somatostatin 0.031 0.0955 0.096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0343 0.0823
Loa Loa (eye worm) hypothetical protein 0.0091 0.0222 0.0408
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.004 0.0077
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.006 0.0116 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.026 0.0618
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0027 0.0007 0.0012
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.019 0.0553 0.0544
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0187 0.0543 0.0537
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.031 0.0955 0.1752
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.022 0.0655 0.0659
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0068 0.0143 0.0141
Echinococcus granulosus tyrosine protein kinase Blk 0.0078 0.0176 0.0177
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0322 0.0995 0.3056
Echinococcus granulosus jun protein 0.0184 0.0532 0.0536
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0121 0.0275
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.0063 0.0168
Onchocerca volvulus 0.031 0.0955 0.2331
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0976 0.319 0.536
Brugia malayi Glutamate receptor 1 precursor 0.0193 0.0564 0.094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Schistosoma mansoni glutamate receptor AMPA 0.0193 0.0564 0.0573
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0036 0.0036 0.0083
Brugia malayi cation channel family protein 0.006 0.0116 0.0186
Loa Loa (eye worm) ion channel NompC 0.006 0.0116 0.0212
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0144 0.04 0.0734
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0658 0.2125 0.521
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0167 0.0475 0.0478
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.006 0.0116 0.0186
Toxoplasma gondii hypothetical protein 0.0118 0.031 0.0597
Mycobacterium ulcerans ferredoxin reductase 0.0263 0.0797 0.2441
Echinococcus multilocularis tyrosine kinase 0.0031 0.0018 0.0018
Loa Loa (eye worm) helicase 0.0037 0.004 0.0073
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0038 0.0043 0.0038
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0119 0.0222
Brugia malayi larval opioid receptor 0.031 0.0955 0.1598
Brugia malayi hypothetical protein 0.0069 0.0146 0.0237
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Echinococcus multilocularis potassium large conductance calcium activated 0.006 0.0116 0.0116
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0143 0.0144
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0032 0.0053
Schistosoma mansoni 60S ribosomal protein L21 0.0074 0.0164 0.0163
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0263 0.0797 0.0801
Schistosoma mansoni vesicular amine transporter 0.006 0.0116 0.0113
Echinococcus multilocularis peregrin 0.0041 0.0053 0.0053
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0263 0.0797 0.2163
Trypanosoma brucei ATP-binding cassette protein, putative 0.0044 0.0063 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.026 0.0618
Loa Loa (eye worm) acetyltransferase 0.0148 0.0412 0.0757
Schistosoma mansoni rab6-interacting 0.0088 0.0209 0.0209
Brugia malayi latrophilin 2 splice variant baaae 0.0147 0.041 0.0681
Toxoplasma gondii NADPH-glutathione reductase 0.0989 0.3235 0.6326
Echinococcus granulosus chromobox protein 2 0.0037 0.004 0.004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.031 0.0955 0.1598
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.031 0.0955 0.1598
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0068 0.0145
Brugia malayi neuropeptide F receptor 0.031 0.0955 0.1598
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0125 0.0126
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0036 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0039 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0412 0.0415
Plasmodium vivax calmodulin, putative 0.0029 0.0014 0.0009
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0075 0.0168 0.0161
Plasmodium falciparum DNA topoisomerase 2 0.0167 0.0475 0.092
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0028 0.0009 0.0009
Trypanosoma cruzi ABC transporter, putative 0.0044 0.0063 0.0057
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0027 0.0006 0.0001
Schistosoma mansoni coup transcription factor 0.0062 0.0125 0.0123
Plasmodium vivax amine transporter, putative 0.0118 0.031 0.059
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.006 0.0116 0.0268
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0084 0.0198 0.0385
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0038 0.0043 0.0043
Schistosoma mansoni amine GPCR 0.1741 0.5757 0.5908
Loa Loa (eye worm) TK protein kinase 0.0069 0.0147 0.027
Entamoeba histolytica hypothetical protein 0.0037 0.004 0.0156
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0162 0.0458 0.0761
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0076 0.0076
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0263 0.0797 0.1557
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0099 0.0248 0.025
Brugia malayi Associated with TFs and helicases family protein 0.0037 0.004 0.0058
Echinococcus multilocularis serotonin transporter 0.0693 0.2241 0.2254
Echinococcus multilocularis Protein lozenge 0.0055 0.0101 0.0102
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0302 0.0297
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.031 0.0313
Loa Loa (eye worm) hepatopoietin HPO2 0.0075 0.0168 0.0308
Toxoplasma gondii hypothetical protein 0.006 0.0116 0.0216
Plasmodium falciparum heterochromatin protein 1 0.0037 0.004 0.0068
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0109 0.028 0.0273
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.019 0.0553 0.0547
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0096
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0263 0.0797 0.0801
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0144 0.04 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.004 0.005 0.0101
Schistosoma mansoni adenoreceptor 0.031 0.0955 0.0975
Echinococcus multilocularis tumor protein p63 0.1428 0.4709 0.4737
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0194 0.0568 0.0577
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0302 0.059
Echinococcus granulosus allatostatin A receptor 0.031 0.0955 0.096
Trichomonas vaginalis apoptosis inducing factor, putative 0.0263 0.0797 0.1939
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0088 0.021 0.0211
Schistosoma mansoni voltage-gated potassium channel 0.0099 0.0247 0.0248
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0118 0.031 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0125 0.0202
Leishmania major hypothetical protein, conserved 0.006 0.0116 0.011
Echinococcus multilocularis transient receptor potential cation channel 0.006 0.0116 0.0116
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.031 0.0955 0.096
Chlamydia trachomatis DNA gyrase subunit A 0.0036 0.0036 0.0083
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.006 0.0116 0.0116
Chlamydia trachomatis thioredoxin reductase 0.0263 0.0797 0.2441
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0068 0.0143 0.0262
Onchocerca volvulus 0.0099 0.0248 0.0594
Trypanosoma cruzi cytochrome P450, putative 0.0121 0.0322 0.0315
Echinococcus granulosus Chromo domain 0.0037 0.004 0.004
Echinococcus granulosus tyrosine protein kinase Lyn 0.0088 0.021 0.0211
Trichomonas vaginalis glucosylceramidase, putative 0.0822 0.2674 0.6561
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0891 0.2906 0.2923
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0043 0.0059 0.0055
Schistosoma mansoni fkbp-rapamycin associated protein 0.0036 0.0036 0.0032
Loa Loa (eye worm) hypothetical protein 0.0171 0.0491 0.09
Schistosoma mansoni loxhd1 0.0088 0.0209 0.0209
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1008 0.3297 0.6053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0125 0.023
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0125 0.0126
Plasmodium vivax DNA gyrase subunit A, putative 0.0036 0.0036 0.0052
Entamoeba histolytica hypothetical protein 0.0073 0.0161 0.0727
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0125 0.0123
Schistosoma mansoni biogenic amine receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Leishmania major cytochrome p450-like protein 0.0121 0.0322 0.0317
Treponema pallidum oxidoreductase 0.0263 0.0797 0.2441
Echinococcus multilocularis RUN 0.0088 0.0209 0.0211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2561 0.8512 0.8511
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0927 0.3026 0.3044
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0084 0.0199 0.0199
Echinococcus multilocularis alpha 1A adrenergic receptor 0.031 0.0955 0.096
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0513
Loa Loa (eye worm) CYP4Cod1 0.0121 0.0322 0.0591
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0125 0.023
Brugia malayi Intermediate filament tail domain containing protein 0.0088 0.0209 0.0343
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0345 0.1075 0.5043
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0117 0.0308 0.0928
Schistosoma mansoni glutamate synthase 0.0263 0.0797 0.0813
Schistosoma mansoni biogenic amine (dopamine) receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0029 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase Src64B 0.0086 0.0204 0.0205
Loa Loa (eye worm) hypothetical protein 0.0088 0.0209 0.0384
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0014 0.0015
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0263 0.0797 0.0801
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.031 0.0955 0.0975
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0263 0.0797 0.3728
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Onchocerca volvulus 0.031 0.0955 0.2331
Schistosoma mansoni voltage-gated potassium channel 0.0084 0.0199 0.0199
Onchocerca volvulus 0.031 0.0955 0.2331
Trichomonas vaginalis Ferredoxin 4 0.0029 0.0012 0.0008
Echinococcus multilocularis ryanodine receptor 44f 0.006 0.0116 0.0116
Schistosoma mansoni voltage-gated cation channel 0.0171 0.0491 0.0498
Echinococcus multilocularis epidermal growth factor receptor 0.018 0.052 0.0523
Echinococcus granulosus calmodulin 0.0029 0.0014 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0121 0.0322 0.0591
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0036 0.0036 0.0083
Brugia malayi ORL1-like opioid receptor 0.031 0.0955 0.1598
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.021 0.062 0.0624
Plasmodium vivax thioredoxin reductase, putative 0.1548 0.511 1
Brugia malayi Augmenter of liver regeneration 0.0075 0.0168 0.0273
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0043 0.0036
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Brugia malayi CHD4 protein 0.0043 0.0059 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Loa Loa (eye worm) hypothetical protein 0.0066 0.0136 0.025
Echinococcus granulosus fmrfamide receptor 0.031 0.0955 0.096
Brugia malayi Cytochrome P450 family protein 0.0218 0.0648 0.1081
Toxoplasma gondii hypothetical protein 0.006 0.0116 0.0216
Schistosoma mansoni tyrosine kinase 0.0086 0.0204 0.0204
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0125 0.0123
Echinococcus multilocularis sodium and chloride dependent glycine 0.0118 0.031 0.0312
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0029 0.0012 0.0003
Giardia lamblia GTOR 0.019 0.0553 0.1679
Trichomonas vaginalis glucosylceramidase, putative 0.0568 0.1823 0.4466
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0034 0.0048
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0043 0.0044
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0168 0.0478 0.0795
Trypanosoma cruzi target of rapamycin kinase 3 0.0151 0.0423 0.0417
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.006 0.0116 0.0268
Toxoplasma gondii thioredoxin reductase 0.1548 0.511 1
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0125 0.0123
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0263 0.0797 0.2441
Echinococcus granulosus orexin receptor type 2 0.031 0.0955 0.096
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0059 0.0114 0.0115
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0121 0.0221
Echinococcus multilocularis glutamate receptor 2 0.0138 0.0378 0.038
Loa Loa (eye worm) G-protein coupled receptor 0.031 0.0955 0.1752
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0113 0.0294 0.0705
Brugia malayi MH2 domain containing protein 0.0261 0.0791 0.1323
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0039 0.0074
Brugia malayi hypothetical protein 0.006 0.0116 0.0186
Echinococcus granulosus hypothetical protein 0.006 0.0116 0.0116
Loa Loa (eye worm) solute carrier family 6 member 4 0.0693 0.2241 0.4114
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.006 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus ATP binding cassette sub family G 0.0044 0.0063 0.0064
Giardia lamblia Glutamate synthase 0.0263 0.0797 0.2434
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0308 0.0303
Schistosoma mansoni sodium/chloride dependent transporter 0.0693 0.2241 0.2296
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0037 0.004 0.0058
Brugia malayi hypothetical protein 0.0033 0.0026 0.0035
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0074 0.0162 0.0383
Loa Loa (eye worm) MH2 domain-containing protein 0.0261 0.0791 0.1453
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0263 0.0797 0.0788
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0161 0.016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0125 0.0202
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0036 0.0036 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0123 0.0329 0.0789
Trichomonas vaginalis set domain proteins, putative 0.1238 0.4071 1
Entamoeba histolytica hypothetical protein 0.0036 0.0036 0.0139
Onchocerca volvulus 0.0118 0.031 0.0747
Entamoeba histolytica hypothetical protein 0.0098 0.0245 0.1127
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0263 0.0797 0.1939
Trichomonas vaginalis glucosylceramidase, putative 0.0539 0.1725 0.4226
Loa Loa (eye worm) hypothetical protein 0.0118 0.031 0.057
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0144 0.0145
Schistosoma mansoni tyrosine kinase 0.0098 0.0244 0.0245
Plasmodium falciparum glutathione reductase 0.0989 0.3235 0.6326
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0116 0.0116
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0043 0.0084
Echinococcus multilocularis musashi 0.0088 0.0209 0.0211
Loa Loa (eye worm) glutamate receptor 0.0027 0.0007 0.0012
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0302 0.1395
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0144 0.0265
Leishmania major protein kinase, putative 0.0039 0.0047 0.0042
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0008 0.0008
Mycobacterium ulcerans electron transfer protein FdxB 0.0029 0.0012 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0116 0.0113
Brugia malayi hypothetical protein 0.0119 0.0316 0.0523
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0125 0.0291
Loa Loa (eye worm) hypothetical protein 0.0052 0.0091 0.0168
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0084 0.0198 0.0584
Echinococcus multilocularis sodium and chloride dependent glycine 0.0118 0.031 0.0312
Mycobacterium ulcerans oxidoreductase 0.0029 0.0012 0.0009
Brugia malayi cytochrome P450 0.0084 0.0198 0.0324
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0084 0.0085
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0029 0.0012 0.0007
Brugia malayi steroid hormone receptor 0.0062 0.0125 0.0202
Schistosoma mansoni metabotropic glutamate receptor 0.0027 0.0007 0.0001
Onchocerca volvulus 0.031 0.0955 0.2331
Schistosoma mansoni voltage-gated potassium channel 0.0074 0.0164 0.0163
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0162 0.0458 0.046
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.022 0.0655 0.0659
Loa Loa (eye worm) hypothetical protein 0.1648 0.5448 1
Brugia malayi isocitrate dehydrogenase 0.0068 0.0143 0.0231
Schistosoma mansoni biogenic amine receptor 0.031 0.0955 0.0975
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis ATP binding cassette sub family G 0.0044 0.0063 0.0064
Echinococcus granulosus glutamate receptor 2 0.022 0.0655 0.0659
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0263 0.0797 0.1557
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.023
Echinococcus multilocularis allatostatin A receptor 0.031 0.0955 0.096
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0125 0.023
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0029 0.0012 0.0022
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0075 0.0168 0.0159
Trichomonas vaginalis Heterochromatin protein, putative 0.0037 0.004 0.0077
Brugia malayi hypothetical protein 0.0073 0.0161 0.0262
Trichomonas vaginalis CMGC family protein kinase 0.0166 0.0472 0.1141
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0658 0.2125 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.031 0.0955 0.0975
Brugia malayi ecdysone receptor 0.0029 0.0014 0.0015
Leishmania major ferredoxin 2fe-2s-like protein 0.0029 0.0012 0.0007
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0088 0.021 0.0211
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.031 0.0597
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0144 0.04 0.0402
Echinococcus granulosus serotonin transporter 0.0693 0.2241 0.2254
Onchocerca volvulus 0.031 0.0955 0.2331
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.006 0.0116 0.0186
Trichomonas vaginalis chromobox protein, putative 0.0037 0.004 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0084 0.0198 0.0385
Brugia malayi nuclear receptor NHR-88 0.0029 0.0014 0.0015
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0118 0.031 0.0312
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0075 0.0168 0.0318
Giardia lamblia NADH oxidase lateral transfer candidate 0.0989 0.3235 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0658 0.2125 0.6557
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0263 0.0797 0.0801
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.019 0.0553 0.2579
Schistosoma mansoni lipoxygenase 0.0449 0.1421 0.1455
Plasmodium falciparum ferredoxin, putative 0.0029 0.0012 0.0013
Treponema pallidum quinoline 2-oxidoreductase 0.0142 0.0393 0.1189
Echinococcus multilocularis neuropeptide receptor A26 0.1774 0.5868 0.5903
Schistosoma mansoni tyrosine kinase 0.0095 0.0233 0.0234
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0449 0.1421 0.143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0129 0.0297
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0084 0.0199 0.02
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0048
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0014 0.0015
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0125 0.0126
Echinococcus granulosus dro:myosuppressin receptor 0.031 0.0955 0.096
Trichomonas vaginalis hypothetical protein 0.0037 0.004 0.0077
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0064 0.0129 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3005 1 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.019 0.0553 0.0544
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0895 0.2921 0.7168
Plasmodium falciparum LCCL domain-containing protein 0.0088 0.0209 0.0399
Schistosoma mansoni rhodopsin-like orphan GPCR 0.031 0.0955 0.0975
Trichomonas vaginalis PIKK family atypical protein kinase 0.0114 0.0297 0.0708
Brugia malayi jmjC domain containing protein 0.0048 0.0076 0.0118
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0118 0.031 0.0312
Echinococcus granulosus voltage gated potassium channel 0.0099 0.0247 0.0249
Schistosoma mansoni lipoxygenase 0.0291 0.0893 0.0911
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Trichomonas vaginalis inositol monophosphatase, putative 0.0117 0.0308 0.0738
Echinococcus granulosus transient receptor potential cation channel 0.006 0.0116 0.0116
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0302 0.0555
Leishmania major calmodulin, putative 0.0029 0.0014 0.0008
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0045 0.0067 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Echinococcus multilocularis voltage gated potassium channel 0.0099 0.0247 0.0249
Echinococcus granulosus voltage dependent calcium channel 0.0171 0.0491 0.0493
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0028 0.0009 0.0007
Brugia malayi hypothetical protein 0.0029 0.0014 0.0015
Echinococcus multilocularis calmodulin 0.0029 0.0014 0.0014
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0076 0.0072
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0121 0.0121
Mycobacterium ulcerans DNA gyrase subunit B 0.0097 0.0242 0.0721
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.004 0.0077
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0263 0.0797 0.2441
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0263 0.0797 0.0788
Trypanosoma cruzi calmodulin, putative 0.0029 0.0014 0.0007
Echinococcus granulosus g protein coupled receptor 0.031 0.0955 0.096
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0062 0.0131
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0029 0.0012 0.0013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0125 0.0126
Loa Loa (eye worm) RGC/RGC protein kinase 0.0035 0.0031 0.0058
Trypanosoma cruzi DNA topoisomerase II, putative 0.0158 0.0445 0.0438
Trypanosoma brucei DNA topoisomerase ii 0.0187 0.0543 0.0535
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0068 0.0143 0.0277
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0037 0.004 0.004
Schistosoma mansoni two-pore calcium channel 0.006 0.0116 0.0113
Onchocerca volvulus 0.031 0.0955 0.2331
Brugia malayi 6-phosphofructokinase 0.0116 0.0304 0.0503
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.022 0.0655 0.0659
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0025 0.002
Onchocerca volvulus 0.031 0.0955 0.2331
Echinococcus granulosus CalModulin family member cmd 1 0.0029 0.0014 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Toxoplasma gondii target of rapamycin (TOR), putative 0.0141 0.039 0.0753
Toxoplasma gondii transporter, cation channel family protein 0.006 0.0116 0.0216
Echinococcus granulosus tyrosine kinase 0.0078 0.0176 0.0177
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0976 0.319 0.3271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0141 0.039 0.0938
Echinococcus granulosus two pore calcium channel protein 1 0.006 0.0116 0.0116
Loa Loa (eye worm) cytochrome P450 family protein 0.0218 0.0648 0.1189
Loa Loa (eye worm) hypothetical protein 0.0041 0.0052 0.0095
Echinococcus granulosus shaker cognate 0.006 0.0116 0.0116
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0044 0.0063 0.0098
Toxoplasma gondii isocitrate dehydrogenase 0.0068 0.0143 0.0269
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0422 0.1332 0.2606
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0083 0.0193 0.0194
Echinococcus granulosus potassium voltage gated channel subfamily D 0.006 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase Fyn 0.0086 0.0204 0.0205
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0308 0.03
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0263 0.0797 0.2441
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Schistosoma mansoni biogenic amine (dopamine) receptor 0.031 0.0955 0.0975
Brugia malayi Heterochromatin protein 1 0.0107 0.0273 0.0451
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1191 0.3912 0.3907
Trypanosoma brucei trypanothione reductase 0.1548 0.511 0.5105
Trichomonas vaginalis chromobox protein, putative 0.0074 0.0162 0.0378
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.006 0.0116 0.0186
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.006 0.0116 0.0113
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0076 0.0139
Echinococcus granulosus G protein coupled receptor 139 0.031 0.0955 0.096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2561 0.8512 0.8511
Schistosoma mansoni eyes absent homolog 0.0091 0.0222 0.0223
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0144 0.04 0.0402
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0386 0.1211 0.2368
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Leishmania major phosphatidylinositol 3-kinase, putative 0.0064 0.0129 0.0124
Brugia malayi hypothetical protein 0.031 0.0955 0.1598
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0073
Echinococcus granulosus serotonin receptor 0.031 0.0955 0.096
Echinococcus granulosus survival motor neuron protein 1 0.1003 0.3282 0.3302
Echinococcus multilocularis short transient receptor potential channel 6 0.006 0.0116 0.0116
Onchocerca volvulus 0.0029 0.0014 0.0019
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.019 0.0553 0.0556
Echinococcus multilocularis neuropeptide receptor 0.031 0.0955 0.096
Brugia malayi PAS domain containing protein 0.0048 0.0076 0.0118
Schistosoma mansoni chromobox protein 0.0037 0.004 0.0035
Echinococcus granulosus two pore calcium channel protein 2 0.006 0.0116 0.0116
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0263 0.0797 0.3728
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0012 0.0022
Echinococcus granulosus potassium voltage gated channel protein 0.006 0.0116 0.0116
Echinococcus granulosus receptor type guanylyl cyclase 0.0035 0.0031 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0084 0.0085
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Plasmodium falciparum thioredoxin reductase 0.1548 0.511 1
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Plasmodium falciparum thioredoxin reductase 0.0989 0.3235 0.6326
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.006 0.0116 0.0113
Echinococcus granulosus GPCR family 2 0.0068 0.0144 0.0145
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0263 0.0797 0.1939
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0014 0.0015
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0028 0.0009 0.0016
Treponema pallidum hypothetical protein 0.0146 0.0404 0.1224
Schistosoma mansoni voltage-dependent calcium channel 0.006 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.006 0.0116 0.0212
Loa Loa (eye worm) neuropeptide F receptor 0.031 0.0955 0.1752
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0084 0.0198 0.0584
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0125 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0302 0.0722
Echinococcus granulosus tyrosine protein kinase HCK 0.0069 0.0147 0.0148
Echinococcus multilocularis potassium voltage gated channel protein 0.006 0.0116 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0184 0.0532 0.0536
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0114 0.0298 0.0299
Brugia malayi Cytochrome P450 family protein 0.0121 0.0322 0.0533
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0084 0.0155
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1112 0.3649 0.714
Echinococcus multilocularis transcription factor Dp 1 0.0084 0.0196 0.0197
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0043 0.0044
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus neuropeptide Y receptor 0.031 0.0955 0.096
Schistosoma mansoni tyrosine kinase 0.0095 0.0233 0.0234
Loa Loa (eye worm) DR-78 0.0029 0.0014 0.0027
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0084 0.0199 0.02
Schistosoma mansoni hypothetical protein 0.0037 0.0039 0.0034
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0088 0.0194
Schistosoma mansoni tyrosine kinase 0.018 0.052 0.0529
Trypanosoma brucei calmodulin 0.0029 0.0014 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0048
Echinococcus granulosus Adrenodoxin mitochondrial 0.0029 0.0012 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0693 0.2241 0.3763
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0989 0.3235 0.3231
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.0121 0.0346
Plasmodium falciparum ferrodoxin reductase-like protein 0.0263 0.0797 0.155
Echinococcus multilocularis geminin 0.1403 0.4623 0.465
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0121 0.0115
Schistosoma mansoni cellular tumor antigen P53 0.0209 0.0617 0.0628
Schistosoma mansoni voltage-gated potassium channel 0.0224 0.0668 0.0681
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0014 0.0015
Giardia lamblia DNA topoisomerase II 0.0158 0.0446 0.1346
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0125 0.0202
Echinococcus multilocularis tyrosine protein kinase Srms 0.0078 0.0176 0.0177
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0084 0.0198 0.0385
Loa Loa (eye worm) heterochromatin protein 1 0.0107 0.0273 0.0501
Echinococcus multilocularis survival motor neuron protein 1 0.1003 0.3282 0.3302
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Schistosoma mansoni adrenodoxin 0.0029 0.0012 0.0007
Entamoeba histolytica disulphide oxidoreductase, putative 0.0263 0.0797 0.3728
Schistosoma mansoni hypothetical protein 0.0894 0.2917 0.299
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0167 0.0475 0.079
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0014 0.0009
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0037 0.004 0.0156
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0084 0.0198 0.0584
Loa Loa (eye worm) TK/EGFR protein kinase 0.018 0.052 0.0955
Echinococcus multilocularis fmrfamide receptor 0.031 0.0955 0.096
Echinococcus granulosus lamin dm0 0.0088 0.0209 0.0211
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.002 0.0029
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0166 0.0472 0.0867
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0047 0.0082
Entamoeba histolytica thioredoxin reductase, putative 0.0263 0.0797 0.3728
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0119 0.0119
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0171 0.0491 0.0493
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0114 0.0298 0.0299
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0263 0.0797 0.0801
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.031 0.0955 0.1598
Echinococcus multilocularis rhodopsin orphan GPCR 0.031 0.0955 0.096
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0151 0.0349
Onchocerca volvulus 0.0089 0.0214 0.051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0102 0.0259 0.0617
Onchocerca volvulus 0.0088 0.0209 0.0498
Leishmania major hypothetical protein, conserved 0.0263 0.0797 0.0792
Trypanosoma cruzi trypanothione reductase, putative 0.0989 0.3235 0.323
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0168 0.0478 0.0926
Loa Loa (eye worm) hypothetical protein 0.031 0.0955 0.1752
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0083 0.0193 0.0194
Brugia malayi bZIP transcription factor family protein 0.0184 0.0532 0.0887
Loa Loa (eye worm) hypothetical protein 0.0075 0.0167 0.0307
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0125 0.0126
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0422 0.1332 0.4102
Onchocerca volvulus 0.031 0.0955 0.2331
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0007 0.0002
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0008 0.0008
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.019 0.0553 0.2579
Loa Loa (eye worm) hypothetical protein 0.0311 0.096 0.1762
Loa Loa (eye worm) hypothetical protein 0.0113 0.0294 0.054
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0068 0.0143 0.0144
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.002 0.0062
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0039 0.0034
Echinococcus granulosus metabotropic glutamate receptor 2 0.0027 0.0007 0.0007
Echinococcus granulosus lamin 0.0088 0.0209 0.0211
Echinococcus granulosus thyrotropin releasing hormone receptor 0.031 0.0955 0.096
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0629 0.2026 0.2021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0026 0.0048
Plasmodium vivax glutathione reductase, putative 0.1548 0.511 1
Trypanosoma brucei protein kinase, putative 0.0166 0.0472 0.0464
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.006 0.0116 0.0113
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0263 0.0797 0.2441

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Activity against P. berghei in mice. ChEMBL. 6991691
Activity (binding) Ability to inhibit hypoxanthine-guanine phosphoribosyltransferase in crude extracts of H.Ep.-2 cells. ChEMBL. 6991691
Activity (functional) Not significant 0 Activity against P. berghei in mice. ChEMBL. 6991691
Activity (binding) NI 0 Ability to inhibit hypoxanthine-guanine phosphoribosyltransferase in crude extracts of H.Ep.-2 cells. ChEMBL. 6991691

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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