Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.022 | 0.1301 | 0.206 | |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0024 | 0.0057 | 0.0085 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0235 | 0.1399 | 0.6458 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0065 | 0.0098 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0059 | 0.0281 | 0.3905 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0335 | 0.2031 | 0.949 |
Plasmodium vivax | hypothetical protein, conserved | 0.0143 | 0.0815 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0336 | 0.0505 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0336 | 0.0505 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0024 | 0.0057 | 0.0694 |
Loa Loa (eye worm) | hypothetical protein | 0.0395 | 0.2414 | 0.3625 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0059 | 0.0281 | 0.344 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0124 | 0.0124 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0316 | 0.144 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0024 | 0.0057 | 0.0694 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0143 | 0.0815 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0336 | 0.0336 |
Mycobacterium tuberculosis | Conserved protein | 0.0143 | 0.0815 | 0.1347 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0143 | 0.0815 | 0.1347 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.022 | 0.1301 | 0.1953 |
Plasmodium vivax | acyl carrier protein, putative | 0.0024 | 0.0057 | 0.0694 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.0496 | 0.0745 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0235 | 0.1399 | 0.2377 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0147 | 0.0214 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0024 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0297 | 0.0447 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.025 | 0.1492 | 0.6903 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0134 | 0.076 | 0.3461 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0059 | 0.0281 | 0.0421 |
Mycobacterium ulcerans | acyl carrier protein | 0.0024 | 0.0057 | 0.0265 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0297 | 0.1355 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0057 | 0.0486 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0134 | 0.0755 | 0.124 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0024 | 0.0057 | 0.0265 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0096 | 0.0437 |
Echinococcus multilocularis | peregrin | 0.0028 | 0.0086 | 0.0086 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0351 | 0.2137 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0086 | 0.0129 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0065 | 0.0799 |
Mycobacterium tuberculosis | Meromycolate extension acyl carrier protein AcpM | 0.0024 | 0.0057 | 0.0008 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0071 | 0.0356 | 0.0557 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0322 | 0.0322 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0134 | 0.0201 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0074 | 0.0375 | 0.1753 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0059 | 0.0281 | 0.344 |
Toxoplasma gondii | ABC1 family protein | 0.0143 | 0.0815 | 0.5466 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0052 | 0.035 |
Brugia malayi | AMP-binding enzyme family protein | 0.022 | 0.1301 | 0.1953 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0143 | 0.0815 | 0.1313 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0297 | 0.0447 |
Schistosoma mansoni | acyl carrier protein | 0.0024 | 0.0057 | 0.0258 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0141 | 0.0141 |
Echinococcus granulosus | expressed protein | 0.0033 | 0.0112 | 0.0169 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0335 | 0.2031 | 0.9503 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0086 | 0.0577 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0143 | 0.0815 | 0.1347 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0032 | 0.0107 | 0.6244 |
Onchocerca volvulus | 0.0143 | 0.0815 | 0.1257 | |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0235 | 0.1399 | 0.2101 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0207 | 0.1221 | 0.1833 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0052 | 0.0728 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0196 | 0.115 | 0.5265 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0074 | 0.0375 | 0.0569 |
Mycobacterium ulcerans | beta-lactamase | 0.0143 | 0.0815 | 0.3815 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.0356 | 0.4361 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0169 | 0.0978 | 0.1635 |
Brugia malayi | Muscleblind-like protein | 0.1063 | 0.6659 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0143 | 0.0815 | 0.1224 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0059 | 0.0281 | 0.1278 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0235 | 0.1399 | 0.6545 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.025 | 0.1492 | 0.2541 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0742 | 0.1115 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0143 | 0.0815 | 0.1313 |
Onchocerca volvulus | 0.0134 | 0.076 | 0.1164 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0297 | 0.0297 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0052 | 0.0245 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0081 | 0.0419 | 0.0647 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0028 | 0.0086 | 0.0129 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0059 | 0.0281 | 0.1312 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0143 | 0.0815 | 0.1347 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0143 | 0.0815 | 0.1224 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0297 | 0.1355 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0112 | 0.0157 |
Schistosoma mansoni | methyltransferase-related | 0.0071 | 0.0356 | 0.162 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0322 | 0.0322 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.0427 | 0.0641 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0071 | 0.0356 | 0.0534 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0297 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Loa Loa (eye worm) | acyl carrier protein | 0.0108 | 0.0592 | 0.0889 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0024 | 0.0057 | 0.0008 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0107 | 0.1317 |
Echinococcus granulosus | dihydrofolate reductase | 0.0335 | 0.2031 | 0.305 |
Mycobacterium tuberculosis | Conserved protein | 0.0143 | 0.0815 | 0.1347 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0143 | 0.0815 | 0.1347 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0.0086 | 0.0577 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0032 | 0.0107 | 0.072 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0322 | 0.1466 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.0336 | 0.0505 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0057 | 0.0271 | 0.0385 |
Mycobacterium tuberculosis | Conserved protein | 0.0143 | 0.0815 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0095 | 0.0143 |
Trichomonas vaginalis | rotamase, putative | 0.0032 | 0.0107 | 0.0149 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0024 | 0.0057 | 0.0085 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0235 | 0.1399 | 0.2377 |
Echinococcus granulosus | geminin | 0.036 | 0.2195 | 0.3296 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0155 | 0.0893 | 0.4179 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0074 | 0.0375 | 0.1547 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0228 | 0.1353 | 0.2296 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0189 | 0.1107 | 0.518 |
Brugia malayi | AMP-binding enzyme family protein | 0.0072 | 0.0365 | 0.0548 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0059 | 0.0281 | 0.1881 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0123 | 0.0689 | 0.4621 |
Onchocerca volvulus | 0.0082 | 0.0427 | 0.0613 | |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0057 | 0.0258 |
Brugia malayi | dihydrofolate reductase family protein | 0.0335 | 0.2031 | 0.305 |
Leishmania major | hypothetical protein, conserved | 0.0143 | 0.0815 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0128 | 0.0718 | 0.881 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0123 | 0.0689 | 0.314 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0297 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0147 | 0.0221 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0059 | 0.0281 | 0.344 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.0496 | 0.0745 |
Giardia lamblia | Methyltransferase like 2 | 0.0071 | 0.0356 | 1 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0235 | 0.1399 | 0.6458 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0024 | 0.0057 | 0.0021 |
Toxoplasma gondii | type I fatty acid synthase | 0.0036 | 0.0135 | 0.0904 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0052 | 0.1864 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.025 | 0.1492 | 0.2541 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0036 | 0.0135 | 0.0146 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0134 | 0.0201 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0024 | 0.0057 | 0.0265 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0147 | 0.015 |
Loa Loa (eye worm) | fatty acid synthase | 0.0232 | 0.1379 | 0.2071 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0086 | 0.0391 |
Brugia malayi | Pre-SET motif family protein | 0.0123 | 0.0689 | 0.1035 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0235 | 0.1399 | 0.2377 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0297 | 0.1355 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0128 | 0.0718 | 0.881 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0059 | 0.0281 | 0.344 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0052 | 0.035 |
Trichomonas vaginalis | esterase, putative | 0.0143 | 0.0815 | 0.1313 |
Brugia malayi | beta-lactamase family protein | 0.0143 | 0.0815 | 0.1224 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0128 | 0.0718 | 0.881 |
Brugia malayi | Dihydrofolate reductase | 0.0335 | 0.2031 | 0.305 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.022 | 0.1301 | 0.2204 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0065 | 0.0907 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0351 | 0.2137 | 0.3681 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0141 | 0.064 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0141 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0136 | 0.0771 | 0.1158 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0128 | 0.0718 | 0.881 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0207 | 0.1221 | 0.1833 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0143 | 0.0815 | 0.3715 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0166 | 0.0244 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0143 | 0.0815 | 0.3815 |
Mycobacterium leprae | conserved hypothetical protein | 0.0143 | 0.0815 | 0.366 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0135 | 0.0202 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0022 | 0.0048 | 0.0073 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0322 | 0.0483 |
Loa Loa (eye worm) | acyl carrier protein | 0.0024 | 0.0057 | 0.0085 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0077 | 0.0098 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0095 | 0.051 | 0.0807 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0065 | 0.0098 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0322 | 0.0483 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0297 | 0.1355 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0096 | 0.0096 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0322 | 0.1466 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0071 | 0.0356 | 0.0535 |
Mycobacterium ulcerans | acyl carrier protein | 0.0024 | 0.0057 | 0.0265 |
Mycobacterium leprae | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0057 | 0.0021 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0322 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0141 | 1 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0036 | 0.0135 | 0.0146 |
Mycobacterium tuberculosis | Probable acyl carrier protein AcpA (ACP) | 0.0024 | 0.0057 | 0.0008 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0143 | 0.0815 | 0.0815 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0024 | 0.0057 | 0.0265 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0143 | 0.0815 | 0.1313 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0336 | 0.1533 |
Echinococcus multilocularis | muscleblind protein | 0.1063 | 0.6659 | 0.6659 |
Echinococcus granulosus | muscleblind protein | 0.1063 | 0.6659 | 1 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0297 | 0.0447 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0024 | 0.0057 | 0.0008 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0024 | 0.0057 | 0.0008 |
Echinococcus granulosus | NADH dehydrogenase | 0.0024 | 0.0057 | 0.0085 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0123 | 0.0689 | 0.314 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.0427 | 0.1944 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0024 | 0.0057 | 0.0265 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0141 | 0.0211 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0032 | 0.0107 | 0.1317 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0189 | 0.1107 | 0.518 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0059 | 0.0281 | 0.0421 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0322 | 0.0322 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0166 | 0.018 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0207 | 0.1221 | 0.1833 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0086 | 0.1055 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0024 | 0.0057 | 0.0008 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.025 | 0.1492 | 0.6903 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0065 | 0.0799 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0028 | 0.0086 | 0.0392 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0024 | 0.0057 | 0.0008 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0143 | 0.0815 | 0.1224 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.0157 | 0.0157 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0123 | 0.0689 | 0.0689 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.0805 | 0.1208 |
Brugia malayi | Bromodomain containing protein | 0.0028 | 0.0086 | 0.0129 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0.0086 | 0.0049 |
Echinococcus multilocularis | expressed protein | 0.0033 | 0.0112 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0086 | 0.0129 |
Schistosoma mansoni | dihydrofolate reductase | 0.0335 | 0.2031 | 0.9253 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0136 | 0.0771 | 0.1158 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.0336 | 0.0505 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0086 | 0.0129 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0123 | 0.0689 | 0.314 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0143 | 0.0815 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0065 | 0.0799 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0149 | 0.0855 | 0.0855 |
Mycobacterium ulcerans | thioesterase | 0.0196 | 0.115 | 0.538 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0057 | 0.0008 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.012 | 0.1469 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0024 | 0.0057 | 0.0265 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0057 | 0.0265 |
Onchocerca volvulus | 0.0143 | 0.0815 | 0.1257 | |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0427 | 0.0641 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0028 | 0.0086 | 0.0129 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0072 | 0.0365 | 0.0552 |
Loa Loa (eye worm) | hypothetical protein | 0.1063 | 0.6659 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.0356 | 0.0535 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0322 | 0.0483 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0235 | 0.1399 | 0.6545 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0143 | 0.0815 | 0.3815 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0152 | 0.0874 | 0.5862 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0086 | 0.0129 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.0427 | 0.0641 |
Leishmania major | acyl carrier protein, putative | 0.0024 | 0.0057 | 0.0694 |
Onchocerca volvulus | 0.003 | 0.0095 | 0.0064 | |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0155 | 0.0893 | 0.4179 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0143 | 0.0815 | 0.1347 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0052 | 0.0245 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.025 | 0.1492 | 0.6979 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0141 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0215 | 0.0322 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.2195 | 1 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0024 | 0.0057 | 0.2016 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0036 | 0.0135 | 0.0146 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0119 | 0.066 | 0.4427 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0141 | 1 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.2195 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0149 | 0.0855 | 0.1284 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0141 | 0.064 |
Chlamydia trachomatis | acyl carrier protein | 0.0024 | 0.0057 | 0.0279 |
Plasmodium vivax | SET domain protein, putative | 0.0123 | 0.0689 | 0.8453 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0024 | 0.0057 | 0.0085 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0032 | 0.0107 | 0.1317 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0143 | 0.0815 | 0.1347 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0143 | 0.0815 | 0.1313 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0112 | 0.0157 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0036 | 0.0135 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0143 | 0.0815 | 0.1347 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0149 | 0.0855 | 0.1284 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0322 | 0.0483 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0112 | 0.0169 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0036 | 0.0135 | 0.0146 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.025 | 0.1492 | 0.6903 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0028 | 0.0086 | 0.0086 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0336 | 0.0526 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0128 | 0.0718 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0143 | 0.0815 | 0.3815 |
Onchocerca volvulus | 0.0974 | 0.6095 | 1 | |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.0496 | 0.0496 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0228 | 0.1353 | 0.2296 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0134 | 0.0201 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0134 | 0.0611 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0142 | 0.0805 | 0.1208 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.0052 | 0.0257 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0143 | 0.0815 | 0.1224 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.0427 | 0.0427 |
Mycobacterium leprae | conserved hypothetical protein | 0.0024 | 0.0057 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.0805 | 0.3666 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0278 | 0.0417 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0065 | 0.0437 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0149 | 0.0855 | 0.1284 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0134 | 0.0611 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0235 | 0.1399 | 0.6545 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0297 | 0.0447 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0059 | 0.0281 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0136 | 0.0771 | 0.1158 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0335 | 0.2031 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0143 | 0.0815 | 0.1224 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0059 | 0.0281 | 0.1312 |
Mycobacterium ulcerans | polyketide synthase | 0.0235 | 0.1399 | 0.6545 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.0855 | 0.3896 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0192 | 0.1127 | 0.1897 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0033 | 0.0112 | 0.0169 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0336 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1221 | 0.1833 |
Echinococcus granulosus | peregrin | 0.0028 | 0.0086 | 0.0129 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0096 | 0.0437 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0059 | 0.0281 | 0.0421 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.025 | 0.1492 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0077 | 0.0098 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0167 | 0.0969 | 0.6494 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0689 | 0.1035 |
Mycobacterium ulcerans | polyketide synthase | 0.025 | 0.1492 | 0.6979 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0118 | 0.0657 | 0.0986 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0059 | 0.0281 | 0.0281 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0322 | 0.0483 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0322 | 0.1466 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0424 | 0.2597 | 0.4207 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0057 | 0.0265 |
Plasmodium falciparum | acyl carrier protein | 0.0024 | 0.0057 | 0.0787 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0.0086 | 0.1197 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0322 | 0.1466 |
Schistosoma mansoni | rotamase | 0.0033 | 0.0112 | 0.0511 |
Onchocerca volvulus | 0.0028 | 0.0086 | 0.0048 | |
Loa Loa (eye worm) | hypothetical protein | 0.1063 | 0.6659 | 1 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0024 | 0.0057 | 0.0085 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0024 | 0.0057 | 0.0057 |
Onchocerca volvulus | 0.0143 | 0.0815 | 0.1257 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0057 | 0.0486 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0235 | 0.1399 | 0.6545 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.025 | 0.1492 | 0.6979 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0065 | 0.0907 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0297 | 0.0447 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0143 | 0.0815 | 1 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0196 | 0.115 | 0.1938 |
Echinococcus multilocularis | geminin | 0.036 | 0.2195 | 0.2195 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0032 | 0.0107 | 0.1317 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0052 | 0.0641 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0446 | 0.2736 | 0.4108 |
Onchocerca volvulus | 0.0409 | 0.2505 | 0.4054 | |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0034 | 0.012 | 0.1667 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0856 | 0.5345 | 0.8026 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0009 | 0.0013 |
Echinococcus multilocularis | muscleblind protein 1 | 0.1063 | 0.6659 | 0.6659 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.0855 | 0.3896 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0335 | 0.2031 | 0.305 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0059 | 0.0281 | 0.1381 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.0855 | 0.3896 |
Mycobacterium tuberculosis | Acyl carrier protein (ACP) MbtL | 0.0024 | 0.0057 | 0.0008 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0024 | 0.0057 | 0.0265 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0059 | 0.0281 | 0.1312 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0275 | 0.1846 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0024 | 0.0057 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0135 | 0.0202 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0351 | 0.2137 | 0.3681 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.025 | 0.1492 | 0.2541 |
Treponema pallidum | acyl carrier protein | 0.0024 | 0.0057 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0086 | 0.0392 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0297 | 0.1355 |
Mycobacterium ulcerans | thioesterase TesA | 0.0196 | 0.115 | 0.538 |
Brugia malayi | SET domain containing protein | 0.0016 | 0.0009 | 0.0013 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0052 | 0.0641 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0335 | 0.2031 | 0.3493 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0123 | 0.0689 | 0.1035 |
Mycobacterium leprae | Probable lipase LipE | 0.0143 | 0.0815 | 0.366 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0335 | 0.2031 | 0.2031 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0021 | 0.0038 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0322 | 0.0483 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0149 | 0.0855 | 0.1284 |
Mycobacterium ulcerans | lipase LipD | 0.0143 | 0.0815 | 0.3815 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0147 | 0.0221 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0123 | 0.0689 | 0.0689 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0143 | 0.0815 | 0.1313 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0059 | 0.0281 | 0.344 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0189 | 0.1107 | 0.5059 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0065 | 0.0799 |
Brugia malayi | beta-lactamase | 0.0143 | 0.0815 | 0.1224 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.0375 | 0.1707 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0351 | 0.2137 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0166 | 0.0244 |
Trichomonas vaginalis | set domain proteins, putative | 0.0974 | 0.6095 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0915 | 0.5717 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0065 | 0.0799 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0336 | 0.0526 |
Echinococcus granulosus | AMP dependent ligase | 0.0024 | 0.0057 | 0.0085 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0336 | 0.1533 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0147 | 0.0214 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0143 | 0.0815 | 0.3715 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0149 | 0.0855 | 0.0855 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0052 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0815 | 0.1224 |
Echinococcus multilocularis | AMP dependent ligase | 0.0024 | 0.0057 | 0.0057 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0024 | 0.0057 | 0.0379 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0155 | 0.0893 | 0.4033 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.0157 | 0.0235 |
Brugia malayi | Pre-SET motif family protein | 0.0856 | 0.5345 | 0.8026 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0072 | 0.0365 | 0.1707 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0096 | 0.0144 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0128 | 0.0718 | 0.4816 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0141 | 0.0211 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 3.44 uM | Binding affinity against human IMR 90 fetal lung fibroblast bradykinin receptor B2 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.